# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF1181 PF06680.11 EGB01700.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) DUF3883 PF13020.6 EGB01704.1 - 1.8e-13 50.3 0.0 2.3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) GTP_EFTU PF00009.27 EGB01705.1 - 1.6e-42 145.3 0.1 1.9e-42 145.0 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGB01705.1 - 1.6e-06 28.2 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB01705.1 - 0.0016 17.9 0.0 0.02 14.4 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit SIS_2 PF13580.6 EGB01705.1 - 0.07 13.1 0.2 0.15 12.1 0.1 1.6 1 1 0 1 1 1 0 SIS domain HTH_47 PF16221.5 EGB01705.1 - 0.086 12.4 0.3 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 winged helix-turn-helix EGF_2 PF07974.13 EGB01706.1 - 0.015 15.7 7.4 0.015 15.7 7.4 3.2 3 0 0 3 3 3 0 EGF-like domain DSL PF01414.19 EGB01706.1 - 6.1 7.2 13.1 4.2 7.7 2.9 3.4 3 0 0 3 3 3 0 Delta serrate ligand PfkB PF00294.24 EGB01707.1 - 1.5e-27 96.7 0.3 1.7e-27 96.5 0.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CBM_6 PF03422.15 EGB01709.1 - 2.6e-05 24.5 0.2 4.5e-05 23.7 0.2 1.5 1 1 0 1 1 1 1 Carbohydrate binding module (family 6) CBM_35 PF16990.5 EGB01709.1 - 0.027 14.7 0.1 0.042 14.1 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) HD_4 PF13328.6 EGB01710.1 - 0.037 13.8 1.0 0.17 11.6 0.5 2.0 1 1 1 2 2 2 0 HD domain AMP-binding PF00501.28 EGB01711.1 - 0.069 11.7 0.2 0.088 11.4 0.2 1.1 1 0 0 1 1 1 0 AMP-binding enzyme DUF3515 PF12028.8 EGB01711.1 - 2.8 7.6 8.6 18 5.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3515) Nuf2 PF03800.14 EGB01712.1 - 0.24 11.5 0.0 0.74 9.9 0.0 1.8 1 1 1 2 2 2 0 Nuf2 family AAA PF00004.29 EGB01713.1 - 2e-09 38.0 0.0 6.1e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB01713.1 - 1.5e-06 28.7 1.7 4.4e-06 27.2 1.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGB01713.1 - 0.00038 20.4 0.0 0.0007 19.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 EGB01713.1 - 0.00076 19.1 1.3 0.0042 16.7 1.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGB01713.1 - 0.00081 19.7 0.1 0.0023 18.2 0.0 1.8 2 1 1 3 3 3 1 AAA domain Rad17 PF03215.15 EGB01713.1 - 0.0024 17.8 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 EGB01713.1 - 0.0026 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGB01713.1 - 0.0045 16.7 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGB01713.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 EGB01713.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB01713.1 - 0.017 15.5 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EGB01713.1 - 0.022 14.9 0.5 0.076 13.2 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGB01713.1 - 0.03 14.9 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB01713.1 - 0.041 13.3 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EGB01713.1 - 0.064 12.5 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 EGB01713.1 - 0.066 13.7 0.0 0.089 13.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EGB01713.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGB01713.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 EGB01713.1 - 0.12 12.2 0.3 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 AAA+ lid domain AAA_23 PF13476.6 EGB01713.1 - 0.14 12.6 0.0 0.21 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB01713.1 - 0.16 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGB01713.1 - 0.24 10.5 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) LBR_tudor PF09465.10 EGB01715.1 - 0.0013 18.4 1.2 0.0025 17.6 1.2 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Presenilin PF01080.17 EGB01716.1 - 3.2e-13 49.2 2.5 1.5e-07 30.6 0.6 2.0 1 1 1 2 2 2 2 Presenilin Adeno_PIX PF03955.14 EGB01716.1 - 0.058 13.6 0.9 0.058 13.6 0.9 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Trp_Tyr_perm PF03222.13 EGB01717.1 - 4.8e-10 39.0 2.1 6.4e-09 35.3 2.1 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Se-cys_synth_N PF12390.8 EGB01717.1 - 7.1 7.0 10.2 1.7 8.9 2.7 2.8 1 1 2 3 3 3 0 Selenocysteine synthase N terminal SAP PF02037.27 EGB01719.1 - 0.0044 16.7 0.2 0.09 12.6 0.0 2.6 1 1 1 2 2 2 2 SAP domain DUF4472 PF14739.6 EGB01719.1 - 2.4 9.0 9.0 0.23 12.2 2.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) LRR_6 PF13516.6 EGB01720.1 - 1.7e-24 83.7 13.8 2.3e-07 30.3 0.1 7.9 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EGB01720.1 - 5.1e-07 29.9 8.2 0.099 13.1 0.1 5.5 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB01720.1 - 1.9e-05 24.6 2.4 17 6.4 0.1 6.0 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 EGB01720.1 - 0.00031 20.4 17.0 0.69 9.7 0.4 5.9 3 3 0 3 3 3 3 Leucine rich repeat Beta_helix PF13229.6 EGB01721.1 - 0.00031 20.6 0.0 0.0011 18.8 0.0 1.9 1 1 0 1 1 1 1 Right handed beta helix region Mntp PF02659.15 EGB01722.1 - 0.0099 15.6 0.5 3.6 7.3 0.0 2.1 2 0 0 2 2 2 2 Putative manganese efflux pump DUF3093 PF11292.8 EGB01722.1 - 0.02 15.2 1.0 0.041 14.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) HemY_N PF07219.13 EGB01722.1 - 0.029 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Orai-1 PF07856.12 EGB01722.1 - 1.4 8.6 9.7 3.6 7.2 9.7 1.6 1 1 0 1 1 1 0 Mediator of CRAC channel activity Pkinase PF00069.25 EGB01726.1 - 2.2e-36 125.6 0.0 3.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB01726.1 - 2.7e-15 56.4 0.0 4.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB01726.1 - 0.0015 18.6 2.5 0.034 14.1 0.4 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Phage_GPA PF05840.13 EGB01726.1 - 0.099 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Kdo PF06293.14 EGB01726.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.30 EGB01727.1 - 0.011 16.1 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 0 C2 domain DUF1818 PF08848.11 EGB01728.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) CAP_N PF01213.19 EGB01728.1 - 4 6.8 4.6 3.3 7.1 2.5 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GBV-C_env PF12786.7 EGB01729.1 - 0.0063 15.2 0.3 0.0071 15.1 0.3 1.1 1 0 0 1 1 1 1 GB virus C genotype envelope IN_DBD_C PF00552.21 EGB01729.1 - 0.41 10.0 4.1 0.25 10.6 0.6 2.3 2 0 0 2 2 2 0 Integrase DNA binding domain SepF PF04472.12 EGB01730.1 - 0.059 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Cell division protein SepF RR_TM4-6 PF06459.12 EGB01730.1 - 0.24 11.2 2.4 0.27 11.0 2.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRiA4_ORF3 PF07929.11 EGB01731.1 - 0.048 13.4 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein AAA_30 PF13604.6 EGB01732.1 - 1.4e-07 31.4 4.8 2.3e-07 30.7 4.8 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGB01732.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB01732.1 - 0.0016 18.8 0.5 0.0022 18.3 0.5 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB01732.1 - 0.0023 18.3 2.7 0.015 15.7 2.7 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGB01732.1 - 0.0034 17.0 3.6 0.004 16.7 2.7 1.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EGB01732.1 - 0.0048 16.8 0.1 0.007 16.2 0.1 1.3 1 0 0 1 1 1 1 Helicase CbiA PF01656.23 EGB01732.1 - 0.01 15.9 0.4 0.017 15.2 0.4 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EGB01732.1 - 0.012 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 EGB01732.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family zf-C2H2_4 PF13894.6 EGB01732.1 - 0.046 14.6 0.1 0.25 12.3 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Mg_chelatase PF01078.21 EGB01732.1 - 0.048 13.0 0.5 0.079 12.3 0.5 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2054 PF10218.9 EGB01732.1 - 0.078 13.1 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) AAA_28 PF13521.6 EGB01732.1 - 0.083 13.1 0.2 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGB01732.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 EGB01732.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 EGB01732.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Myosin_head PF00063.21 EGB01734.1 - 1.6e-24 86.2 0.2 1.7e-24 86.1 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Herpes_Helicase PF02689.14 EGB01734.1 - 0.0042 15.1 0.3 0.0042 15.1 0.3 1.0 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 EGB01734.1 - 0.013 15.8 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGB01734.1 - 0.052 13.3 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGB01734.1 - 0.077 12.3 0.1 0.12 11.6 0.1 1.4 1 1 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EGB01734.1 - 0.13 12.3 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 EGB01734.1 - 0.13 11.3 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Hpr_kinase_C PF07475.12 EGB01734.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain HEAT PF02985.22 EGB01735.1 - 0.52 10.7 5.0 59 4.3 0.1 4.6 4 0 0 4 4 4 0 HEAT repeat DNA_pol_phi PF04931.13 EGB01738.1 - 0.07 11.2 0.0 0.088 10.9 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 EGB01739.1 - 0.0017 19.2 0.2 4.8 8.2 0.0 4.1 4 1 1 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 EGB01739.1 - 0.056 14.0 0.2 1.4 9.5 0.1 3.1 2 1 0 2 2 2 0 PQQ-like domain TT_ORF2a PF08197.11 EGB01739.1 - 0.078 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 pORF2a truncated protein Thioredoxin_7 PF13899.6 EGB01740.1 - 1.1e-10 41.6 0.7 4.1e-10 39.7 0.7 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB01740.1 - 0.0023 18.4 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 EGB01740.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Ank_2 PF12796.7 EGB01741.1 - 1.9e-18 66.8 2.3 2.7e-09 37.5 0.2 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB01741.1 - 1.2e-11 44.8 3.0 7.8e-06 26.3 0.5 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB01741.1 - 1.7e-11 44.0 1.6 1.3e-07 31.8 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGB01741.1 - 1.9e-07 30.8 0.4 1.4e-05 25.1 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGB01741.1 - 3.5e-06 27.2 2.6 1.5e-05 25.1 0.4 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Crisp PF08562.10 EGB01743.1 - 1.6 9.4 36.0 12 6.6 6.7 3.8 1 1 2 3 3 3 0 Crisp Aldo_ket_red PF00248.21 EGB01746.1 - 3.5e-17 62.5 0.0 3.8e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flavin_Reduct PF01613.18 EGB01746.1 - 0.037 14.1 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Flavin reductase like domain ERO1 PF04137.15 EGB01747.1 - 2.2e-13 50.1 0.1 5.3e-11 42.3 0.1 2.0 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) FG-GAP_2 PF14312.6 EGB01748.1 - 1.6e-17 63.5 30.7 9.4e-06 25.8 5.7 3.2 3 0 0 3 3 3 3 FG-GAP repeat Ig_mannosidase PF17753.1 EGB01748.1 - 0.004 16.9 0.0 11 5.8 0.0 3.1 3 0 0 3 3 3 1 Ig-fold domain CE2_N PF17996.1 EGB01748.1 - 0.0067 16.4 0.1 10 6.1 0.0 3.0 3 0 0 3 3 3 1 Carbohydrate esterase 2 N-terminal HTH_43 PF09904.9 EGB01748.1 - 0.018 15.0 0.6 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DUF3081 PF11280.8 EGB01748.1 - 0.02 14.7 2.0 4.3 7.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3081) Lsr2 PF11774.8 EGB01748.1 - 0.086 13.0 0.7 8.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Lsr2 LEA_2 PF03168.13 EGB01748.1 - 0.38 11.3 2.4 36 5.0 0.0 2.9 3 0 0 3 3 3 0 Late embryogenesis abundant protein Ge1_WD40 PF16529.5 EGB01748.1 - 1.1 8.1 5.0 32 3.3 0.1 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MDMPI_C PF07398.11 EGB01748.1 - 1.8 9.5 11.3 5.4 7.9 1.3 2.8 1 1 2 3 3 3 0 MDMPI C-terminal domain Cloacin PF03515.14 EGB01748.1 - 4.3 6.9 4.8 14 5.3 3.5 2.0 1 1 0 1 1 1 0 Colicin-like bacteriocin tRNase domain ketoacyl-synt PF00109.26 EGB01755.1 - 1.9e-32 112.8 8.6 2.2e-32 112.6 8.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain BACON PF13004.7 EGB01755.1 - 0.039 13.9 0.2 0.086 12.8 0.2 1.6 1 0 0 1 1 1 0 Putative binding domain, N-terminal HECT PF00632.25 EGB01758.1 - 2.4e-26 92.9 0.0 2.6e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PX PF00787.24 EGB01759.1 - 3.5e-05 23.7 0.0 8.2e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 PX domain DnaJ PF00226.31 EGB01760.1 - 3e-11 43.3 0.0 6.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Nucleotid_trans PF03407.16 EGB01761.1 - 0.00014 22.0 0.0 0.00054 20.0 0.0 1.8 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Chlam_PMP PF02415.17 EGB01762.1 - 0.26 11.8 16.6 0.41 11.2 0.5 4.8 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TruB_N PF01509.18 EGB01766.1 - 0.044 14.2 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) RimM PF01782.18 EGB01769.1 - 6.1e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 RimM N-terminal domain RINGv PF12906.7 EGB01772.1 - 2e-11 43.8 2.7 2.9e-11 43.3 2.7 1.2 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EGB01772.1 - 0.046 14.1 2.0 0.094 13.1 2.0 1.5 1 1 0 1 1 1 0 Ring finger domain DUF4611 PF15387.6 EGB01772.1 - 0.083 13.1 0.3 0.083 13.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 EGB01772.1 - 1.6 9.1 13.7 0.21 12.0 8.9 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 EGB01772.1 - 2.1 6.4 7.7 3.2 5.7 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 EGB01774.1 - 7e-11 42.6 0.1 1.2e-10 41.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB01774.1 - 2.8e-07 30.7 0.4 0.00036 20.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB01774.1 - 4.9e-07 29.6 0.6 0.21 12.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EGB01774.1 - 3.6e-06 27.4 0.5 0.034 14.7 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB01774.1 - 0.00014 22.1 0.7 0.1 13.1 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeat CASP_C PF08172.12 EGB01775.1 - 0.00074 18.9 0.8 0.0011 18.4 0.1 1.6 1 1 1 2 2 2 1 CASP C terminal BRE1 PF08647.11 EGB01775.1 - 0.1 12.7 0.3 0.1 12.7 0.3 3.4 2 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 EGB01775.1 - 0.11 13.0 9.3 0.039 14.4 4.9 1.9 2 0 0 2 2 2 0 Fez1 SlyX PF04102.12 EGB01775.1 - 0.25 12.0 14.0 5.9 7.6 1.6 3.9 3 1 0 3 3 3 0 SlyX T3SS_needle_E PF08988.10 EGB01775.1 - 0.28 11.4 0.2 0.28 11.4 0.2 4.9 4 1 1 5 5 5 0 Type III secretion system, cytoplasmic E component of needle DegS PF05384.11 EGB01775.1 - 0.31 10.5 5.3 4.5 6.7 0.7 2.3 1 1 1 2 2 2 0 Sensor protein DegS Atg14 PF10186.9 EGB01775.1 - 0.37 9.8 1.0 0.71 8.9 1.0 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EGB01775.1 - 0.4 9.5 9.4 0.41 9.5 3.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Lebercilin PF15619.6 EGB01775.1 - 2.7 7.6 8.3 0.82 9.3 1.6 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 EGB01775.1 - 3.4 7.0 7.2 3.4 7.1 4.2 2.1 2 1 0 2 2 2 0 Golgin subfamily A member 5 APG6_N PF17675.1 EGB01775.1 - 4.1 7.9 22.8 4.3 7.9 9.6 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region CS PF04969.16 EGB01776.1 - 9.2e-06 26.6 0.0 1.5e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 CS domain MoCF_biosynth PF00994.24 EGB01776.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Probable molybdopterin binding domain C2 PF00168.30 EGB01777.1 - 1.5e-12 47.7 0.0 2.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 EGB01778.1 - 2.3e-17 63.1 0.2 3.4e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB01778.1 - 5.9e-12 45.4 2.4 1e-11 44.6 2.4 1.5 1 0 0 1 1 1 1 Ion channel IRK PF01007.20 EGB01778.1 - 0.00031 20.6 0.2 0.00057 19.7 0.2 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DUF5380 PF17351.2 EGB01778.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5380) Cytochrom_B_C PF00032.17 EGB01779.1 - 2.2e-09 37.5 0.1 3.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Acyl-CoA_dh_1 PF00441.24 EGB01780.1 - 3.8e-20 72.6 2.1 1.1e-18 67.9 2.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGB01780.1 - 0.00018 21.6 0.0 0.00048 20.3 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGB01780.1 - 0.0042 17.4 0.2 0.014 15.6 0.2 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.25 EGB01782.1 - 1.5e-14 53.9 0.3 2.2e-14 53.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB01782.1 - 0.00085 19.3 0.2 0.0013 18.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Na_H_Exchanger PF00999.21 EGB01783.1 - 4.6e-16 58.6 1.5 4.6e-16 58.6 1.5 1.4 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EGB01783.1 - 0.03 14.6 0.1 0.093 13.0 0.1 2.0 1 1 0 1 1 1 0 TrkA-N domain AAA_16 PF13191.6 EGB01785.1 - 0.0011 19.4 0.0 0.0011 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGB01785.1 - 0.026 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGB01785.1 - 0.067 13.2 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 EGB01785.1 - 0.074 13.3 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB01785.1 - 0.087 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EGB01785.1 - 0.09 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EGB01785.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGB01785.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EGB01785.1 - 0.17 12.4 0.0 0.2 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EGB01785.1 - 0.2 11.0 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_30 PF13604.6 EGB01785.1 - 0.22 11.2 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain GBP PF02263.19 EGB01788.1 - 1.3e-62 211.4 0.0 1.5e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGB01788.1 - 0.077 13.1 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RHD3 PF05879.12 EGB01788.1 - 0.077 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) WW PF00397.26 EGB01789.1 - 1.7e-21 75.9 16.2 6.7e-09 35.7 0.4 3.4 3 0 0 3 3 3 3 WW domain DUF3681 PF12442.8 EGB01790.1 - 0.16 12.4 1.5 0.22 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) DUF1168 PF06658.12 EGB01791.1 - 0.064 13.1 8.0 0.11 12.3 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) OrfB_IS605 PF01385.19 EGB01791.1 - 0.12 12.6 5.8 0.19 11.9 5.8 1.2 1 0 0 1 1 1 0 Probable transposase Rrn6 PF10214.9 EGB01791.1 - 1.3 7.4 3.5 1.4 7.3 3.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Glyco_hydro_7 PF00840.20 EGB01792.1 - 1.3e-45 155.9 0.0 1.3e-45 155.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 IQ PF00612.27 EGB01793.1 - 1.3e-34 114.7 14.2 0.14 12.1 0.1 11.2 11 0 0 11 11 11 11 IQ calmodulin-binding motif DUF1069 PF06370.11 EGB01793.1 - 1.3e-06 28.2 6.6 2.3 7.7 0.0 6.3 1 1 7 8 8 8 5 Protein of unknown function (DUF1069) WHEP-TRS PF00458.20 EGB01793.1 - 4 7.7 14.8 17 5.7 3.5 3.4 2 0 0 2 2 2 0 WHEP-TRS domain DUF4160 PF13711.6 EGB01793.1 - 4.6 7.6 7.8 46 4.4 0.0 4.8 4 3 1 5 5 5 0 Domain of unknown function (DUF4160) MFS_1 PF07690.16 EGB01794.1 - 3.3e-05 23.0 13.1 3.8e-05 22.8 13.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily P2X_receptor PF00864.19 EGB01795.1 - 1.9e-08 33.8 0.1 1.1e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 ATP P2X receptor Caroten_synth PF04240.12 EGB01795.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Carotenoid biosynthesis protein EGF_CA PF07645.15 EGB01797.1 - 0.081 13.1 2.1 0.081 13.1 2.1 3.1 1 1 1 2 2 2 0 Calcium-binding EGF domain Sulfotransfer_3 PF13469.6 EGB01799.1 - 0.00012 22.6 0.0 0.0007 20.0 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family TPR_17 PF13431.6 EGB01799.1 - 0.018 15.4 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box PF00646.33 EGB01800.1 - 1.2e-06 28.2 1.0 1.9e-06 27.6 1.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGB01800.1 - 3.9e-06 26.7 0.3 8e-06 25.7 0.3 1.5 1 0 0 1 1 1 1 F-box-like bZIP_2 PF07716.15 EGB01800.1 - 0.017 15.2 0.5 0.029 14.5 0.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 EGB01800.1 - 0.029 14.5 0.1 0.048 13.8 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor Myb_DNA-binding PF00249.31 EGB01802.1 - 5.5e-18 64.9 0.2 5.9e-18 64.8 0.2 1.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB01802.1 - 5.3e-13 49.0 0.0 5.7e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyco_hydro_43 PF04616.14 EGB01803.1 - 3.8e-13 49.4 2.5 1.4e-10 41.0 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 PsbY PF06298.11 EGB01803.1 - 0.043 13.7 0.6 0.067 13.1 0.6 1.3 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) GYF PF02213.16 EGB01804.1 - 4.8e-05 22.9 0.0 9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 GYF domain AAA_5 PF07728.14 EGB01806.1 - 1.2e-18 67.5 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB01806.1 - 3.4e-11 43.1 0.0 5.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB01806.1 - 1.4e-05 25.5 0.5 2.8e-05 24.6 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EGB01806.1 - 2.4e-05 24.8 0.0 3.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 EGB01806.1 - 2.6e-05 24.3 0.0 4.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Midasin AAA lid domain IstB_IS21 PF01695.17 EGB01806.1 - 0.00084 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGB01806.1 - 0.00091 19.8 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB01806.1 - 0.0058 16.4 0.6 0.02 14.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain Dynein_heavy PF03028.15 EGB01806.1 - 0.0078 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain RsgA_GTPase PF03193.16 EGB01806.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EGB01806.1 - 0.031 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGB01806.1 - 0.038 13.2 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 EGB01806.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 EGB01806.1 - 0.043 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB01806.1 - 0.045 14.0 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB01806.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB01806.1 - 0.084 12.2 0.0 0.74 9.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EGB01806.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 EGB01806.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 EGB01806.1 - 0.13 11.2 0.0 0.28 10.1 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 EGB01806.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGB01806.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EGB01806.1 - 0.15 12.5 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 EGB01806.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGB01806.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 EGB01806.1 - 0.24 11.5 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_6 PF12774.7 EGB01806.1 - 0.27 10.1 0.0 4.4 6.2 0.0 2.0 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Trypan_PARP PF05887.11 EGB01807.1 - 5.7 6.9 37.7 0.053 13.5 12.3 2.8 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) zf-C3HC4_3 PF13920.6 EGB01808.1 - 7.7e-14 51.3 12.4 8.4e-14 51.2 12.4 1.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB01808.1 - 0.00013 21.9 12.7 0.00015 21.6 12.7 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGB01808.1 - 0.00032 21.0 12.6 0.00043 20.6 12.6 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGB01808.1 - 0.00063 19.6 11.4 0.00076 19.3 11.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGB01808.1 - 0.0007 19.4 14.9 0.00089 19.0 14.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC2 PF13490.6 EGB01808.1 - 0.056 13.7 4.9 1.3 9.4 0.7 2.4 2 0 0 2 2 2 0 Putative zinc-finger DUF1644 PF07800.12 EGB01808.1 - 1.2 9.2 10.2 1.3 9.1 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Yae1_N PF09811.9 EGB01809.1 - 5.7e-05 22.7 27.0 0.32 10.7 2.0 5.5 1 1 3 4 4 4 4 Essential protein Yae1, N terminal DUF1759 PF03564.15 EGB01811.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) PAS_9 PF13426.7 EGB01812.1 - 0.094 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 PAS domain DUF3303 PF11746.8 EGB01812.1 - 0.15 12.4 0.0 0.21 11.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3303) RAP PF08373.10 EGB01813.1 - 9.8e-20 70.4 0.0 1.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 EGB01813.1 - 6.3e-06 26.3 0.0 9.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 REase_MTES_1575 SAP PF02037.27 EGB01813.1 - 6.6e-05 22.6 0.1 0.0002 21.0 0.1 1.9 1 0 0 1 1 1 1 SAP domain V-ATPase_H_C PF11698.8 EGB01814.1 - 1e-39 135.3 0.0 1.1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.23 EGB01814.1 - 2.2e-05 24.4 0.1 0.031 14.3 0.0 2.2 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB01814.1 - 0.0018 18.6 0.0 0.005 17.2 0.0 1.7 1 1 1 2 2 2 2 HEAT repeats DRIM PF07539.12 EGB01814.1 - 0.0033 15.8 0.0 0.0048 15.3 0.0 1.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.22 EGB01814.1 - 0.013 15.7 0.0 11 6.6 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat Arm_2 PF04826.13 EGB01814.1 - 0.021 14.3 0.0 0.025 14.1 0.0 1.0 1 0 0 1 1 1 0 Armadillo-like Cyt-b5 PF00173.28 EGB01814.1 - 0.021 14.9 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Arm_3 PF16186.5 EGB01814.1 - 0.041 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 Atypical Arm repeat MFS_1_like PF12832.7 EGB01816.1 - 2.3e-13 49.8 1.6 3.1e-13 49.3 1.6 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGB01816.1 - 0.001 18.0 11.7 0.0014 17.6 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SAM_1 PF00536.30 EGB01816.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Cwf_Cwc_15 PF04889.12 EGB01816.1 - 0.15 11.7 3.6 0.21 11.3 3.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LAT PF15234.6 EGB01816.1 - 0.58 9.9 3.2 0.85 9.3 3.2 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells FYDLN_acid PF09538.10 EGB01816.1 - 1 10.0 8.6 1.7 9.4 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CAMSAP_CC1 PF17095.5 EGB01817.1 - 0.0065 16.3 0.6 0.78 9.6 0.0 2.5 2 0 0 2 2 2 2 Spectrin-binding region of Ca2+-Calmodulin Rx_N PF18052.1 EGB01817.1 - 0.036 14.3 5.3 1.5 9.1 0.5 2.2 1 1 1 2 2 2 0 Rx N-terminal domain SSrecog PF03531.14 EGB01817.1 - 0.036 14.0 2.1 1.5 8.8 0.1 2.9 2 1 1 3 3 3 0 Structure-specific recognition protein (SSRP1) Elf1 PF05129.13 EGB01817.1 - 0.062 13.4 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TLV_coat PF00429.19 EGB01817.1 - 0.18 10.5 2.9 6.8 5.2 0.1 2.7 2 1 1 3 3 3 0 ENV polyprotein (coat polyprotein) Pyrophosphatase PF00719.19 EGB01819.1 - 3.3e-31 108.2 0.2 3.9e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase SHOCT PF09851.9 EGB01820.1 - 0.037 13.8 0.4 0.082 12.7 0.4 1.7 1 0 0 1 1 1 0 Short C-terminal domain VCBS PF13517.6 EGB01821.1 - 0.00089 19.8 1.1 0.0021 18.6 1.1 1.6 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB01821.1 - 0.0011 19.0 1.3 0.0043 17.1 1.3 2.0 1 0 0 1 1 1 1 FG-GAP repeat Fibin PF15819.5 EGB01823.1 - 0.067 13.0 0.1 0.078 12.7 0.1 1.1 1 0 0 1 1 1 0 Fin bud initiation factor homologue acVLRF1 PF18859.1 EGB01824.1 - 0.023 15.0 1.8 0.11 12.9 0.1 2.2 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor DUF740 PF05340.12 EGB01825.1 - 0.049 12.4 0.2 0.058 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Mito_carr PF00153.27 EGB01826.1 - 1.2e-36 124.5 5.8 5.5e-14 51.9 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein L_biotic_typeA PF04604.13 EGB01826.1 - 0.064 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Type-A lantibiotic 2OG-FeII_Oxy_3 PF13640.6 EGB01828.1 - 5.8e-12 46.3 0.0 1.2e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB01828.1 - 0.0025 18.3 0.0 0.0093 16.4 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 EGB01828.1 - 0.031 14.1 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family PAZ PF02170.22 EGB01829.1 - 0.00037 20.3 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 PAZ domain Arm PF00514.23 EGB01831.1 - 2.5e-20 71.8 1.8 6e-09 35.6 0.6 3.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB01831.1 - 3.5e-08 33.7 13.2 7.4e-07 29.5 3.4 2.5 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EGB01831.1 - 2.6e-07 31.0 7.8 0.0091 16.5 0.1 4.2 4 0 0 4 4 4 2 HEAT-like repeat Cas_Csx9 PF09658.10 EGB01831.1 - 0.003 16.8 0.1 0.02 14.1 0.1 1.9 1 1 1 2 2 2 1 CRISPR-associated protein (Cas_Csx9) Atx10homo_assoc PF09759.9 EGB01831.1 - 0.0034 17.4 0.0 0.093 12.8 0.2 2.3 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 EGB01831.1 - 0.0036 17.4 10.1 0.036 14.3 0.1 3.9 5 1 1 6 6 6 2 HEAT repeat Arm_2 PF04826.13 EGB01831.1 - 0.013 15.0 0.0 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 Armadillo-like Thioredoxin_7 PF13899.6 EGB01831.1 - 0.037 14.2 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Cnd1 PF12717.7 EGB01831.1 - 0.18 11.8 0.0 0.84 9.7 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 VWA PF00092.28 EGB01833.1 - 6.9e-10 39.4 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGB01833.1 - 1.5e-06 28.2 0.0 4.3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGB01833.1 - 4.3e-06 27.3 0.0 2.1e-05 25.1 0.0 2.0 2 1 1 3 3 3 1 von Willebrand factor type A domain Bax1-I PF01027.20 EGB01835.1 - 1.1e-09 38.4 1.9 1.2e-09 38.3 1.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pyr_redox_2 PF07992.14 EGB01836.1 - 8.6e-13 48.2 0.8 1.1e-12 47.8 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB01836.1 - 8.1e-05 23.1 0.2 0.00014 22.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4423 PF14394.6 EGB01836.1 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) Lycopene_cycl PF05834.12 EGB01836.1 - 0.0032 16.6 0.7 0.14 11.2 0.3 2.5 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EGB01836.1 - 0.032 14.2 0.4 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 EGB01836.1 - 0.11 11.7 0.2 3.7 6.6 0.0 2.2 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGB01836.1 - 0.5 9.9 5.7 6.9 6.1 0.6 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Cpn60_TCP1 PF00118.24 EGB01837.1 - 8.1e-45 153.4 0.2 9e-45 153.2 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_1 PF00076.22 EGB01838.1 - 1.9e-08 34.0 0.0 4.3e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMP2_N PF18590.1 EGB01839.1 - 7.7e-30 103.3 0.1 1e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 EGB01839.1 - 9.1e-05 22.2 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain RNA_pol_Rpb1_5 PF04998.17 EGB01840.1 - 6.5e-09 35.6 0.1 6.8e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 TyeA PF09059.10 EGB01840.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 TyeA Ribosomal_S2 PF00318.20 EGB01841.1 - 5.4e-61 205.6 0.0 6.3e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 MCM_N PF14551.6 EGB01842.1 - 2.1e-05 25.1 0.0 2.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 MCM N-terminal domain MCM_OB PF17207.3 EGB01842.1 - 0.00029 20.7 2.0 0.0036 17.1 1.6 2.6 2 1 0 2 2 2 1 MCM OB domain TPR_12 PF13424.6 EGB01848.1 - 1.4e-12 47.7 25.3 3e-07 30.6 2.0 5.1 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGB01848.1 - 4.2e-10 39.2 31.7 3.7e-07 29.8 0.1 6.1 5 2 0 5 5 5 4 Tetratricopeptide repeat SBP_bac_3 PF00497.20 EGB01848.1 - 0.014 14.8 1.2 0.032 13.6 1.2 1.7 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 TPR_14 PF13428.6 EGB01848.1 - 0.14 13.1 0.1 0.14 13.1 0.1 6.9 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB01848.1 - 0.29 11.4 5.3 5.1 7.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB01848.1 - 0.84 9.6 5.0 5.3 7.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat KR PF08659.10 EGB01850.1 - 4.1e-16 59.4 2.6 7.2e-16 58.6 2.6 1.4 1 0 0 1 1 1 1 KR domain cobW PF02492.19 EGB01856.1 - 3.5e-25 88.6 0.2 4.6e-25 88.2 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NifU PF01106.17 EGB01856.1 - 0.086 13.0 1.1 0.15 12.2 1.1 1.5 1 0 0 1 1 1 0 NifU-like domain RCC1 PF00415.18 EGB01858.1 - 9.1e-37 125.5 21.8 3.9e-16 59.4 0.1 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB01858.1 - 1.5e-16 59.7 36.6 6.4e-08 32.2 3.1 6.3 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat PAP_fibrillin PF04755.12 EGB01859.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 PAP_fibrillin Ank_2 PF12796.7 EGB01860.1 - 2.7e-17 63.1 0.0 7.6e-10 39.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB01860.1 - 3e-13 49.7 1.2 0.00012 22.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB01860.1 - 3e-13 48.6 0.5 4.3e-05 23.6 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EGB01860.1 - 4.2e-12 46.3 0.3 3e-09 37.3 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB01860.1 - 1.2e-11 44.5 0.9 2.6e-05 24.5 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat cNMP_binding PF00027.29 EGB01861.1 - 0.0011 19.1 0.0 0.0014 18.7 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Corona_NS2 PF04753.12 EGB01861.1 - 0.039 14.5 0.0 0.056 14.0 0.0 1.3 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Sel1 PF08238.12 EGB01862.1 - 3.9e-11 43.2 3.9 1.8e-06 28.4 0.3 3.7 3 1 0 3 3 3 2 Sel1 repeat TPR_16 PF13432.6 EGB01862.1 - 0.0086 16.7 0.7 0.016 15.8 0.7 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB01862.1 - 0.031 14.1 3.5 0.3 11.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB01862.1 - 0.042 14.1 0.2 0.095 13.0 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB01862.1 - 0.046 14.4 0.7 50 4.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB01862.1 - 0.14 13.0 0.5 5 8.2 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB01862.1 - 0.31 11.2 5.2 0.67 10.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB01862.1 - 1.7 9.0 0.1 1.7 9.0 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 EGB01865.1 - 1.6e-18 67.7 0.1 1.9e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.9 EGB01865.1 - 0.0083 16.0 0.8 0.018 14.9 0.8 1.5 1 0 0 1 1 1 1 Rossmann-like domain LRV PF01816.17 EGB01865.1 - 2.4 8.7 7.4 2.3 8.8 0.2 3.4 2 1 1 3 3 3 0 Leucine rich repeat variant Pheromone PF08015.11 EGB01869.1 - 0.082 14.0 0.4 0.33 12.0 0.0 2.2 2 1 0 2 2 2 0 Fungal mating-type pheromone Arm PF00514.23 EGB01871.1 - 8.3e-25 86.0 14.4 5.2e-09 35.8 0.4 5.4 5 0 0 5 5 5 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB01871.1 - 2.2e-06 27.9 16.2 2.9e-05 24.4 4.8 3.2 1 1 2 3 3 3 2 HEAT repeats IFRD PF05004.13 EGB01871.1 - 0.0027 16.9 1.9 0.032 13.3 1.9 2.0 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Clp_N PF02861.20 EGB01871.1 - 0.0063 16.6 2.2 0.33 11.1 0.1 3.0 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component HEAT PF02985.22 EGB01871.1 - 0.0081 16.3 14.2 4 8.0 0.1 6.3 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 EGB01871.1 - 0.019 15.5 20.9 0.46 11.0 1.4 4.9 2 2 3 6 6 6 0 HEAT-like repeat Arm_2 PF04826.13 EGB01871.1 - 0.055 12.9 0.0 0.083 12.3 0.0 1.5 1 1 0 1 1 1 0 Armadillo-like HEAT_PBS PF03130.16 EGB01871.1 - 0.53 11.1 0.2 0.53 11.1 0.2 5.8 5 2 0 5 5 5 0 PBS lyase HEAT-like repeat TF_Zn_Ribbon PF08271.12 EGB01872.1 - 0.00019 20.9 0.3 0.00046 19.6 0.3 1.7 1 1 0 1 1 1 1 TFIIB zinc-binding Desulfoferrod_N PF06397.12 EGB01872.1 - 2.8 7.6 10.5 3.2 7.4 3.9 2.7 1 1 1 2 2 2 0 Desulfoferrodoxin, N-terminal domain Sel1 PF08238.12 EGB01874.1 - 1e-10 41.9 3.0 3.4e-08 33.9 0.3 2.4 2 1 0 2 2 2 2 Sel1 repeat C2-C2_1 PF11618.8 EGB01874.1 - 0.12 12.5 0.0 0.13 12.3 0.0 1.0 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 TPR_2 PF07719.17 EGB01874.1 - 0.2 11.9 5.9 0.33 11.2 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB01874.1 - 0.52 11.0 6.6 0.4 11.4 0.7 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat NADH_4Fe-4S PF10589.9 EGB01875.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PDZ PF00595.24 EGB01876.1 - 0.011 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EGB01876.1 - 0.087 12.7 0.3 0.48 10.3 0.2 2.1 2 0 0 2 2 2 0 PDZ domain DUF5545 PF17699.1 EGB01878.1 - 0.0038 17.1 2.2 0.027 14.3 0.5 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5545) Ank_3 PF13606.6 EGB01879.1 - 0.00014 22.0 0.1 0.72 10.6 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGB01879.1 - 0.0013 19.0 3.9 0.055 13.8 0.1 3.1 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB01879.1 - 0.0023 18.5 0.0 0.01 16.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB01879.1 - 0.0092 16.6 0.3 0.26 11.9 0.2 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Cupin_8 PF13621.6 EGB01879.1 - 0.028 14.2 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain HMG_box PF00505.19 EGB01880.1 - 0.023 15.1 12.1 1 9.8 3.5 3.3 1 1 1 2 2 2 0 HMG (high mobility group) box Autophagy_act_C PF03987.15 EGB01881.1 - 2.1e-19 69.9 1.1 2.5e-19 69.6 1.1 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain BUD22 PF09073.10 EGB01882.1 - 4.9e-05 22.9 23.3 6e-05 22.6 23.3 1.1 1 0 0 1 1 1 1 BUD22 ProQ PF04352.13 EGB01882.1 - 0.11 12.4 8.4 0.19 11.7 8.4 1.3 1 0 0 1 1 1 0 ProQ/FINO family Plasmodium_Vir PF05795.11 EGB01882.1 - 0.64 9.4 2.3 0.77 9.1 2.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FUSC PF04632.12 EGB01882.1 - 6.1 5.3 7.7 7.5 5.0 7.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UDG PF03167.19 EGB01883.1 - 9.4e-11 41.9 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily IMP2_N PF18590.1 EGB01884.1 - 2e-23 82.7 0.0 3.7e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 EGB01884.1 - 8.8e-08 31.9 0.0 1.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain ERM PF00769.19 EGB01884.1 - 0.12 12.2 9.0 0.15 11.9 9.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mod_r PF07200.13 EGB01884.1 - 0.58 10.2 5.0 0.91 9.6 5.0 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 EGB01884.1 - 1.5 7.7 7.5 2.1 7.2 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Mobilization_B PF17511.2 EGB01884.1 - 2.6 8.4 12.9 1.7 9.0 11.0 1.7 2 0 0 2 2 2 0 Mobilization protein B GlutR_N PF05201.15 EGB01885.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain Methyltransf_34 PF11312.8 EGB01885.1 - 1.4 8.1 5.9 2.1 7.5 5.9 1.6 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase Ank_5 PF13857.6 EGB01886.1 - 7.3e-07 29.4 0.2 1.6e-06 28.3 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB01886.1 - 7e-05 23.3 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB01886.1 - 0.011 16.3 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB01886.1 - 0.031 14.8 0.0 0.09 13.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 EGB01886.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Methyltrans_RNA PF04452.14 EGB01887.1 - 8.5e-24 84.1 0.0 1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase PIF1 PF05970.14 EGB01888.1 - 0.018 14.2 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase RsgA_GTPase PF03193.16 EGB01888.1 - 0.03 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EGB01888.1 - 0.1 13.1 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter D5_N PF08706.11 EGB01888.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 D5 N terminal like AAA_16 PF13191.6 EGB01888.1 - 0.21 11.9 0.0 0.3 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain HMG_box PF00505.19 EGB01890.1 - 6.2e-06 26.5 14.4 0.19 12.2 0.9 4.6 3 1 1 4 4 4 4 HMG (high mobility group) box LPD11 PF18824.1 EGB01890.1 - 0.00061 19.8 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 11 Hjc PF01870.18 EGB01890.1 - 0.015 15.3 0.4 0.31 11.1 0.0 2.3 1 1 1 2 2 2 0 Archaeal holliday junction resolvase (hjc) MCRS_N PF13325.6 EGB01890.1 - 0.096 12.7 0.1 16 5.4 0.0 2.3 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein zf-MYST PF17772.1 EGB01891.1 - 3.5e-16 58.6 0.2 5.5e-16 57.9 0.2 1.3 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGB01891.1 - 6.2e-12 45.2 0.1 1.1e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MOZ_SAS PF01853.18 EGB01891.1 - 0.0062 16.2 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family APA3_viroporin PF11289.8 EGB01892.1 - 0.0065 16.1 0.1 0.007 16.0 0.1 1.1 1 0 0 1 1 1 1 Coronavirus accessory protein 3a Pribosyltran_N PF13793.6 EGB01895.1 - 0.00035 20.5 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase TarH PF02203.15 EGB01895.1 - 0.04 13.9 2.3 0.06 13.3 2.3 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue VCBS PF13517.6 EGB01896.1 - 3.6e-44 149.2 82.8 7.3e-11 42.5 3.5 7.2 2 2 5 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AbfS_sensor PF18225.1 EGB01896.1 - 1.9e-05 24.5 0.0 16 5.5 0.0 5.6 6 0 0 6 6 6 0 Sensor histidine kinase (AbfS) sensor domain HTH_31 PF13560.6 EGB01896.1 - 6.2e-05 23.3 1.3 19 5.7 0.0 5.8 5 1 1 6 6 6 0 Helix-turn-helix domain BBS2_Mid PF14783.6 EGB01896.1 - 0.00082 19.4 3.8 7.4 6.7 0.0 5.5 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Dockerin_1 PF00404.18 EGB01896.1 - 0.001 19.2 38.5 0.89 9.8 0.2 7.6 8 0 0 8 8 8 3 Dockerin type I domain CbiA PF01656.23 EGB01896.1 - 0.0023 18.0 2.9 31 4.6 0.1 5.0 3 2 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Hydrolase_4 PF12146.8 EGB01896.1 - 0.0062 15.8 4.6 9 5.5 0.0 4.9 5 1 0 5 5 5 1 Serine aminopeptidase, S33 FG-GAP PF01839.23 EGB01896.1 - 0.0097 16.0 2.9 0.0097 16.0 2.9 8.2 8 0 0 8 8 8 2 FG-GAP repeat Marek_A PF02124.15 EGB01896.1 - 0.017 14.9 0.4 0.56 10.0 0.1 3.1 3 1 1 4 4 4 0 Marek's disease glycoprotein A Peptidase_S29 PF02907.15 EGB01896.1 - 0.02 14.7 1.6 22 4.7 0.0 4.7 2 2 3 5 5 5 0 Hepatitis C virus NS3 protease vWF_A PF12450.8 EGB01896.1 - 0.03 14.2 7.1 46 4.1 0.0 5.6 6 0 0 6 6 6 0 von Willebrand factor TcdB_toxin_midN PF12256.8 EGB01896.1 - 0.081 12.3 35.2 1.2 8.5 0.4 7.0 2 2 5 7 7 7 0 Insecticide toxin TcdB middle/N-terminal region IGPD PF00475.18 EGB01896.1 - 9.7 6.5 8.6 13 6.1 0.1 4.1 5 2 0 6 6 6 0 Imidazoleglycerol-phosphate dehydratase TUDOR_5 PF18359.1 EGB01897.1 - 5.1e-08 32.5 6.2 0.00084 19.0 0.3 2.5 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 EGB01897.1 - 6.5e-07 29.1 0.4 0.0085 15.9 0.0 2.9 3 0 0 3 3 3 2 DNA repair protein Crb2 Tudor domain 53-BP1_Tudor PF09038.10 EGB01897.1 - 6.1e-06 26.2 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 Tumour suppressor p53-binding protein-1 Tudor Agenet PF05641.12 EGB01897.1 - 0.00062 20.2 0.0 0.073 13.6 0.0 2.4 2 0 0 2 2 2 1 Agenet domain DUF4537 PF15057.6 EGB01897.1 - 0.13 12.3 0.1 4.5 7.3 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Chal_sti_synt_N PF00195.19 EGB01899.1 - 0.081 12.3 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Laminin_G_3 PF13385.6 EGB01900.1 - 5.6e-15 55.8 1.5 8.6e-15 55.2 1.5 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EGB01900.1 - 0.15 12.6 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Pro_isomerase PF00160.21 EGB01901.1 - 1.6e-45 155.2 0.0 1.9e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD OxoDH_E1alpha_N PF12573.8 EGB01901.1 - 0.06 13.1 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal SMG1 PF15785.5 EGB01902.1 - 4.1e-06 25.5 0.1 1.1e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Serine/threonine-protein kinase smg-1 IBR PF01485.21 EGB01903.1 - 7.4e-07 29.3 2.3 7.4e-07 29.3 2.3 3.2 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGB01903.1 - 0.00033 20.4 0.5 0.00033 20.4 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB01903.1 - 0.013 15.8 0.4 0.013 15.8 0.4 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 EGB01903.1 - 0.1 12.5 0.4 0.1 12.5 0.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Asp_Arg_Hydrox PF05118.15 EGB01904.1 - 0.0025 17.6 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase SATase_N PF06426.14 EGB01905.1 - 3.7e-19 69.1 0.2 5.2e-19 68.6 0.2 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 EGB01905.1 - 3.8e-10 39.1 7.1 2.5e-05 23.8 1.6 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB01905.1 - 3.8e-06 26.6 9.0 0.00037 20.2 3.6 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase ECH_1 PF00378.20 EGB01906.1 - 4.4e-44 150.7 1.4 6.5e-44 150.1 1.4 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB01906.1 - 1.3e-38 133.3 0.4 1.6e-38 133.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGB01906.1 - 0.077 12.9 0.2 13 5.7 0.0 2.5 2 1 0 2 2 2 0 Peptidase family S49 UT PF03253.14 EGB01907.1 - 3.8e-20 72.2 1.9 3.8e-20 72.2 1.9 1.5 2 0 0 2 2 2 1 Urea transporter PfkB PF00294.24 EGB01908.1 - 4.9e-21 75.3 0.6 6.5e-21 74.9 0.6 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Rieske_2 PF13806.6 EGB01908.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain WD40_4 PF16300.5 EGB01909.1 - 1.5e-21 76.0 0.2 2.1e-21 75.5 0.2 1.2 1 0 0 1 1 1 1 Type of WD40 repeat PI3_PI4_kinase PF00454.27 EGB01910.1 - 6.2e-25 88.4 0.0 2.8e-18 66.7 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase MAPEG PF01124.18 EGB01911.1 - 2.7e-07 30.6 2.5 5e-07 29.7 2.5 1.5 1 1 0 1 1 1 1 MAPEG family ODAM PF15424.6 EGB01912.1 - 0.23 11.0 0.0 0.31 10.6 0.0 1.1 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family UAA PF08449.11 EGB01913.1 - 2.2e-51 174.9 9.6 2.5e-51 174.7 9.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB01913.1 - 1.1e-05 25.6 14.1 0.0029 17.8 9.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EGB01913.1 - 5.3e-05 22.3 5.0 0.00047 19.2 0.1 2.0 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EGB01913.1 - 0.00067 19.1 8.2 0.0019 17.6 8.2 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family Sugar_tr PF00083.24 EGB01914.1 - 9.2e-33 113.8 7.3 1.1e-32 113.5 7.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1422 PF07226.11 EGB01914.1 - 0.046 13.7 1.2 0.046 13.7 1.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) SnoaL_2 PF12680.7 EGB01915.1 - 0.0021 18.7 0.0 0.0035 17.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain EamA PF00892.20 EGB01915.1 - 0.012 15.8 0.5 0.018 15.2 0.5 1.3 1 0 0 1 1 1 0 EamA-like transporter family DnaJ PF00226.31 EGB01916.1 - 2.8e-24 85.0 1.5 3.1e-24 84.9 1.5 1.0 1 0 0 1 1 1 1 DnaJ domain Pkinase_Tyr PF07714.17 EGB01917.1 - 2.5e-28 99.1 0.0 2.6e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB01917.1 - 1e-20 74.2 0.0 1.1e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGB01917.1 - 0.0005 20.1 0.9 0.0014 18.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB01917.1 - 0.0025 16.8 0.0 0.0032 16.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGB01917.1 - 0.0026 17.1 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB01917.1 - 0.038 13.3 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Ubiq_cyt_C_chap PF03981.12 EGB01918.1 - 5.5e-18 65.4 0.6 5.5e-18 65.4 0.6 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Sel1 PF08238.12 EGB01918.1 - 0.00039 21.0 0.6 0.0011 19.5 0.1 2.0 2 0 0 2 2 2 1 Sel1 repeat WD40 PF00400.32 EGB01919.1 - 2.3e-06 28.2 0.1 0.045 14.6 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB01919.1 - 0.03 14.6 0.0 0.48 10.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 EGB01920.1 - 2.5e-08 32.9 0.1 0.0026 17.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB01920.1 - 1.1e-07 32.1 0.1 3.4e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB01920.1 - 1.8e-06 27.4 0.1 0.063 13.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB01920.1 - 1.1e-05 25.1 0.0 0.00012 21.8 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB01920.1 - 1.3e-05 24.4 0.1 0.016 14.7 0.0 2.7 2 0 0 2 2 2 2 EF hand Peptidase_M17 PF00883.21 EGB01921.1 - 1.5e-65 221.5 1.2 1.7e-65 221.4 1.2 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Sulfotransfer_2 PF03567.14 EGB01922.1 - 0.0049 16.8 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family PhyH PF05721.13 EGB01924.1 - 5.2e-13 49.8 0.0 6.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Esterase_phd PF10503.9 EGB01925.1 - 0.0039 16.7 0.1 0.0047 16.5 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 EGB01925.1 - 0.021 14.7 0.6 0.03 14.2 0.6 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGB01925.1 - 0.035 13.9 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EGB01925.1 - 0.16 12.0 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.18 EGB01925.1 - 0.19 11.3 3.0 0.27 10.8 0.8 2.1 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGB01925.1 - 0.69 10.5 9.9 0.12 12.9 5.4 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Trypan_glycop_C PF10659.9 EGB01926.1 - 0.03 14.7 13.6 0.03 14.7 13.6 6.0 3 3 3 6 6 6 0 Trypanosome variant surface glycoprotein C-terminal domain zf-TAZ PF02135.16 EGB01927.1 - 1.3e-08 35.2 2.8 1.3e-08 35.2 2.8 1.9 2 0 0 2 2 2 1 TAZ zinc finger HypA PF01155.19 EGB01927.1 - 0.031 14.3 0.1 0.031 14.3 0.1 1.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EGB01927.1 - 0.24 11.6 4.3 0.14 12.3 0.6 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 EGB01927.1 - 7.3 6.7 8.6 0.64 10.1 0.6 2.6 2 0 0 2 2 2 0 Double zinc ribbon DcpS_C PF11969.8 EGB01928.1 - 1.1e-15 58.1 0.0 1.5e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGB01928.1 - 1.2e-09 38.8 0.0 2.5e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 HIT domain Carbam_trans_C PF16861.5 EGB01929.1 - 9.5e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus PqqD PF05402.12 EGB01929.1 - 0.083 13.2 0.5 0.13 12.6 0.5 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF2464 PF10240.9 EGB01929.1 - 0.28 10.7 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 Histone_H2A_C PF16211.5 EGB01932.1 - 4.7e-18 64.6 1.1 1.4e-17 63.2 1.1 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB01932.1 - 9.3e-12 45.4 0.0 1.1e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB01932.1 - 0.0014 18.9 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone STPPase_N PF16891.5 EGB01933.1 - 1.5e-15 57.4 0.0 3e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 EGB01933.1 - 3.8e-06 27.5 0.1 4.7e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RrnaAD PF00398.20 EGB01934.1 - 0.0041 16.2 0.0 0.0053 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF1485 PF07364.12 EGB01934.1 - 0.13 11.5 4.3 0.13 11.5 1.8 1.9 2 0 0 2 2 2 0 Metallopeptidase family M81 BAT2_N PF07001.11 EGB01936.1 - 1.7e-05 25.4 10.4 3.1e-05 24.5 10.4 1.5 1 0 0 1 1 1 1 BAT2 N-terminus UDPGP PF01704.18 EGB01938.1 - 4.8e-30 104.5 0.0 5.7e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGB01938.1 - 0.0013 19.1 0.2 0.0022 18.3 0.2 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain PD40 PF07676.12 EGB01938.1 - 0.0078 16.1 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 EGB01938.1 - 0.15 11.7 1.0 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature RskA PF10099.9 EGB01941.1 - 1.5 9.1 12.9 2.6 8.3 12.9 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Cupin_8 PF13621.6 EGB01942.1 - 2.8e-06 27.2 0.0 5.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 EGB01942.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.22 EGB01942.1 - 0.19 12.2 0.0 1.1 9.7 0.0 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase DUF5122 PF17164.4 EGB01943.1 - 0.14 12.5 0.2 0.25 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller DUF1631 PF07793.11 EGB01945.1 - 0.5 8.7 4.4 0.59 8.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF5538 PF17692.1 EGB01945.1 - 2.9 8.0 9.1 9.5 6.3 9.1 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5538) VKOR PF07884.14 EGB01947.1 - 2.2e-23 82.8 15.4 4.4e-23 81.8 15.4 1.5 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Ank_2 PF12796.7 EGB01948.1 - 1.3e-11 44.9 0.1 1.7e-07 31.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB01948.1 - 1.5e-07 31.9 0.1 0.001 19.6 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB01948.1 - 3.5e-07 30.3 2.5 0.0013 19.0 0.2 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB01948.1 - 3.5e-06 27.2 1.6 0.00035 20.9 0.1 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EGB01948.1 - 0.00025 21.3 0.3 0.068 13.8 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Pex14_N PF04695.13 EGB01949.1 - 0.019 15.6 0.5 0.019 15.6 0.5 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IBR PF01485.21 EGB01950.1 - 5.4e-12 45.8 4.5 1.8e-06 28.0 0.0 4.5 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGB01950.1 - 4.9e-05 23.3 17.8 0.00015 21.7 1.1 3.2 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 EGB01950.1 - 8.2e-05 22.5 1.9 8.2e-05 22.5 1.9 4.9 3 1 2 5 5 5 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGB01950.1 - 0.00015 22.0 1.0 0.00015 22.0 1.0 5.0 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 EGB01950.1 - 0.0002 21.1 0.7 0.0002 21.1 0.7 4.3 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB01950.1 - 0.004 17.0 1.6 0.004 17.0 1.6 4.9 5 1 0 6 6 6 2 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 EGB01950.1 - 6.3 6.7 9.1 5.4 7.0 0.4 2.5 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) PLA2_B PF01735.18 EGB01952.1 - 3.7e-06 25.6 0.5 4.8e-06 25.2 0.5 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 EGB01952.1 - 0.0056 16.9 7.1 0.0089 16.2 6.6 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3601 PF12208.8 EGB01952.1 - 0.11 12.5 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) DUF3293 PF11697.8 EGB01955.1 - 4.5 7.8 6.5 6.4 7.3 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) WD40 PF00400.32 EGB01956.1 - 2e-19 69.5 3.1 3.8e-05 24.4 0.0 3.0 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB01956.1 - 6.6e-05 23.1 0.0 0.0067 16.7 0.1 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1995 PF09353.10 EGB01961.1 - 6.6e-13 49.1 0.0 8.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) PTCB-BRCT PF12738.7 EGB01963.1 - 0.032 14.2 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Usp PF00582.26 EGB01963.1 - 6.7 7.2 9.4 1.9 9.0 5.4 2.1 2 1 0 2 2 2 0 Universal stress protein family Rad60-SLD PF11976.8 EGB01964.1 - 1.3e-16 60.2 0.5 1.4e-16 60.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGB01964.1 - 1e-11 44.4 0.2 1.1e-11 44.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Imm58 PF15581.6 EGB01965.1 - 0.013 15.6 3.1 31 4.7 0.1 3.8 1 1 2 4 4 4 0 Immunity protein 58 CSN4_RPN5_eIF3a PF18420.1 EGB01965.1 - 0.4 10.9 11.3 1.6e+02 2.6 0.1 6.1 1 1 6 7 7 7 0 CSN4/RPN5/eIF3a helix turn helix domain Asp_Arg_Hydrox PF05118.15 EGB01966.1 - 9.3e-09 35.3 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Ribosomal_L29e PF01779.17 EGB01967.1 - 1e-15 57.8 4.4 1.3e-15 57.5 4.4 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family Proteasome PF00227.26 EGB01969.1 - 6.4e-31 107.3 0.5 7.7e-31 107.1 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 EGB01970.1 - 5.6e-11 42.3 0.0 6.3e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain UvrD_C PF13361.6 EGB01971.1 - 0.0027 17.2 0.8 0.0036 16.7 0.8 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EGB01971.1 - 0.017 14.9 0.2 0.04 13.7 0.2 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SRP68 PF16969.5 EGB01971.1 - 0.12 11.3 0.2 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Ank_4 PF13637.6 EGB01972.1 - 2e-17 63.3 3.4 7.1e-10 39.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB01972.1 - 1.5e-16 60.2 3.7 1.3e-08 35.0 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB01972.1 - 2.1e-16 59.5 6.3 7.9e-09 35.6 0.4 2.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGB01972.1 - 2.1e-16 60.3 0.2 2.7e-16 59.9 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB01972.1 - 4e-15 54.4 0.2 5.8e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat PWWP PF00855.17 EGB01973.1 - 0.0064 16.9 0.7 0.013 15.9 0.7 1.7 1 1 0 1 1 1 1 PWWP domain PT PF04886.12 EGB01976.1 - 6.7e-10 38.4 58.1 5.7e-05 22.6 24.6 3.6 1 1 1 2 2 2 2 PT repeat DUF3185 PF11381.8 EGB01976.1 - 0.031 14.3 0.1 78 3.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Laminin_G_3 PF13385.6 EGB01978.1 - 1.3e-28 100.1 1.4 2.4e-15 57.0 0.6 2.8 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily PT PF04886.12 EGB01978.1 - 0.00032 20.2 47.9 0.0056 16.2 20.8 3.6 2 1 1 3 3 3 3 PT repeat Pentaxin PF00354.17 EGB01978.1 - 0.02 14.6 0.1 1.1 9.0 0.1 2.5 2 1 0 2 2 2 0 Pentaxin family Laminin_G_2 PF02210.24 EGB01978.1 - 0.11 13.0 0.0 0.54 10.8 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain DUF4756 PF15948.5 EGB01979.1 - 0.37 10.6 4.8 0.81 9.5 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) HTH_WhiA PF02650.14 EGB01979.1 - 0.68 10.3 5.0 1.4 9.3 0.8 2.2 2 0 0 2 2 2 0 WhiA C-terminal HTH domain YL1 PF05764.13 EGB01980.1 - 0.00031 20.9 4.2 0.0004 20.6 4.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SRP-alpha_N PF04086.13 EGB01980.1 - 1.2 9.0 8.1 1.6 8.6 8.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SPT6_acidic PF14632.6 EGB01980.1 - 2.2 8.9 7.3 2.5 8.7 2.1 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PhyH PF05721.13 EGB01981.1 - 6.8e-16 59.2 0.2 1.4e-09 38.5 0.1 2.1 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Ion_trans_2 PF07885.16 EGB01982.1 - 9.2e-23 80.0 6.2 2.6e-11 43.3 0.6 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 EGB01982.1 - 0.0078 15.5 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 2 Ion transport protein PepSY_2 PF13670.6 EGB01982.1 - 3.4 7.7 4.5 11 6.1 4.5 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Rad60-SLD PF11976.8 EGB01984.1 - 5.2e-12 45.4 0.0 6.1e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGB01984.1 - 5.3e-08 32.5 0.0 5.7e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family FMN_dh PF01070.18 EGB01985.1 - 2.2e-61 207.8 0.4 2.4e-61 207.7 0.4 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EGB01985.1 - 5e-12 45.6 1.0 7.1e-12 45.1 1.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGB01985.1 - 2.7e-05 23.3 0.8 4.3e-05 22.7 0.6 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EGB01985.1 - 0.0029 17.1 0.1 0.011 15.2 0.0 1.8 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 EGB01985.1 - 0.0034 16.7 0.5 1.4 8.2 0.0 2.1 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 EGB01985.1 - 0.08 12.1 2.1 1.4 8.0 0.1 2.1 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EGB01986.1 - 1.5e-93 313.6 0.6 1.9e-93 313.3 0.6 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EGB01986.1 - 9.4e-09 34.9 0.2 1.5e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGB01986.1 - 8.4e-05 21.7 0.3 0.00014 21.0 0.3 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EGB01986.1 - 0.023 14.0 1.3 4.1 6.6 0.0 2.6 2 1 0 3 3 3 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EGB01986.1 - 0.04 13.4 0.1 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 Histidine biosynthesis protein Arm PF00514.23 EGB01987.1 - 1.6e-45 151.8 8.3 1.3e-08 34.6 0.1 6.0 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat zf-C3HC4_3 PF13920.6 EGB01987.1 - 2.9e-13 49.5 10.1 4.2e-13 48.9 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB01987.1 - 7.6e-07 28.9 10.5 1.3e-06 28.2 10.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HEAT_2 PF13646.6 EGB01987.1 - 1.9e-06 28.2 32.0 0.00066 20.0 4.1 3.7 1 1 4 5 5 5 5 HEAT repeats Arm_2 PF04826.13 EGB01987.1 - 2.7e-05 23.8 0.0 0.034 13.6 0.0 3.2 1 1 3 4 4 4 2 Armadillo-like zf-RING_2 PF13639.6 EGB01987.1 - 3.4e-05 24.1 12.0 5.2e-05 23.5 12.0 1.3 1 0 0 1 1 1 1 Ring finger domain HEAT_EZ PF13513.6 EGB01987.1 - 0.00046 20.6 23.8 0.046 14.2 1.5 5.2 4 1 2 6 6 5 4 HEAT-like repeat HEAT PF02985.22 EGB01987.1 - 0.0062 16.7 11.7 8.4 7.0 0.0 5.9 7 0 0 7 7 6 1 HEAT repeat Cnd1 PF12717.7 EGB01987.1 - 0.0068 16.5 0.0 3.6 7.6 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 zf-C3HC4_2 PF13923.6 EGB01987.1 - 0.015 15.1 11.7 0.023 14.5 11.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MtrA PF04208.14 EGB01987.1 - 0.046 13.4 0.1 9 5.9 0.0 3.5 1 1 3 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit A zf-RING_5 PF14634.6 EGB01987.1 - 0.097 12.6 12.0 0.17 11.9 12.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 EGB01987.1 - 1.8 8.5 6.8 3.2 7.7 6.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HEAT_PBS PF03130.16 EGB01987.1 - 1.9 9.4 31.1 6.5 7.7 1.7 7.1 6 5 0 6 6 6 0 PBS lyase HEAT-like repeat ALF PF03752.13 EGB01987.1 - 2.5 8.1 16.0 12 5.9 1.6 5.4 6 0 0 6 6 6 0 Short repeats of unknown function zf-RING_4 PF14570.6 EGB01987.1 - 8.1 6.3 9.3 16 5.4 9.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cnd2 PF05786.14 EGB01988.1 - 1.1e-27 97.2 0.2 6.5e-27 94.6 0.2 1.9 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EGB01988.1 - 0.18 12.0 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Reovirus_cap PF00979.17 EGB01990.1 - 4.7 6.3 6.4 8.9 5.4 6.4 1.4 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Helicase_C PF00271.31 EGB01991.1 - 1.3e-06 28.7 0.1 2.2e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ZapB PF06005.12 EGB01992.1 - 0.0035 17.7 0.2 0.016 15.6 0.1 2.1 2 0 0 2 2 2 1 Cell division protein ZapB KOW PF00467.29 EGB01993.1 - 0.018 15.0 0.5 0.063 13.2 0.8 1.8 2 0 0 2 2 2 0 KOW motif TrmE_N PF10396.9 EGB01994.1 - 6.3e-35 120.0 0.0 1.5e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EGB01994.1 - 5.7e-20 72.4 0.4 7.6e-20 72.0 0.4 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EGB01994.1 - 3.5e-14 52.9 0.0 5.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGB01994.1 - 0.00043 20.4 0.0 0.00062 19.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EGB01994.1 - 0.00056 19.5 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_28 PF13521.6 EGB01994.1 - 0.0046 17.2 0.1 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain GCV_T PF01571.21 EGB01994.1 - 0.033 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Zeta_toxin PF06414.12 EGB01994.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 EGB01994.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase VCBS PF13517.6 EGB01995.1 - 9.9e-30 102.9 60.1 3.8e-10 40.2 9.1 4.3 1 1 3 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.18 EGB01995.1 - 0.0078 16.4 23.8 1.2 9.4 0.4 5.4 5 0 0 5 5 5 3 Dockerin type I domain AbfS_sensor PF18225.1 EGB01995.1 - 0.022 14.7 0.1 7.4 6.6 0.0 3.7 5 0 0 5 5 5 0 Sensor histidine kinase (AbfS) sensor domain CbiA PF01656.23 EGB01995.1 - 0.022 14.8 0.0 3.2 7.8 0.0 3.4 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain GPS PF01825.21 EGB01995.1 - 0.052 14.1 3.3 0.16 12.5 3.3 1.9 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif Hydrolase_4 PF12146.8 EGB01995.1 - 0.06 12.6 1.2 15 4.8 0.0 3.9 3 1 1 4 4 4 0 Serine aminopeptidase, S33 HTH_31 PF13560.6 EGB01995.1 - 0.16 12.3 2.5 4.7 7.6 0.0 4.2 6 0 0 6 6 6 0 Helix-turn-helix domain EF-hand_5 PF13202.6 EGB01995.1 - 3.5 7.3 37.1 3.7 7.2 1.0 5.4 5 0 0 5 5 5 0 EF hand EMP24_GP25L PF01105.24 EGB01997.1 - 1.7e-29 103.1 0.0 2e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IP_trans PF02121.18 EGB01997.1 - 0.048 13.2 0.2 0.11 12.0 0.1 1.6 1 1 1 2 2 2 0 Phosphatidylinositol transfer protein E1-E2_ATPase PF00122.20 EGB01998.1 - 8.9e-16 57.9 0.0 1e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 E1-E2 ATPase S1 PF00575.23 EGB02000.1 - 1.2e-13 51.1 0.2 1.4e-13 51.0 0.2 1.1 1 0 0 1 1 1 1 S1 RNA binding domain TRAM_2 PF18693.1 EGB02000.1 - 0.0014 18.8 0.1 0.0021 18.2 0.1 1.3 1 0 0 1 1 1 1 TRAM domain RNase_II_C_S1 PF18614.1 EGB02000.1 - 0.0081 16.1 0.2 0.013 15.5 0.2 1.4 1 0 0 1 1 1 1 RNase II-type exonuclease C-terminal S1 domain Sas6_CC PF18594.1 EGB02001.1 - 0.0028 17.4 1.9 64 3.5 0.0 4.2 4 0 0 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain Sbi-IV PF11621.8 EGB02001.1 - 0.0068 16.7 1.4 11 6.4 0.0 4.3 5 0 0 5 5 5 1 C3 binding domain 4 of IgG-bind protein SBI Unstab_antitox PF09720.10 EGB02001.1 - 0.0075 16.3 4.4 37 4.5 0.0 4.3 4 0 0 4 4 4 0 Putative addiction module component DUF3618 PF12277.8 EGB02001.1 - 0.012 15.8 12.6 3.8 7.9 0.2 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3618) DUF3106 PF11304.8 EGB02001.1 - 0.017 15.6 0.6 39 4.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3106) DUF4936 PF16290.5 EGB02001.1 - 0.055 14.2 0.1 23 5.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) DUF3545 PF12065.8 EGB02001.1 - 0.25 11.4 3.6 1.1e+02 3.0 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3545) DUF2555 PF10742.9 EGB02001.1 - 0.35 10.7 4.1 29 4.6 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2555) PNKP-ligase_C PF16536.5 EGB02001.1 - 0.68 10.2 10.5 35 4.8 0.1 4.5 4 0 0 4 4 4 0 PNKP adenylyltransferase domain, C-terminal region DUF5476 PF17570.2 EGB02001.1 - 0.68 10.4 6.1 50 4.4 0.0 4.2 4 0 0 4 4 4 0 Family of unknown function (DUF5476) EF-hand_7 PF13499.6 EGB02002.1 - 4.5e-07 30.2 0.2 5.2e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB02002.1 - 3.6e-06 26.5 0.3 7.5e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGB02002.1 - 1.6e-05 24.1 0.1 2.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EGB02002.1 - 6.9e-05 22.6 3.2 0.015 15.1 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB02002.1 - 0.0071 16.6 0.0 0.008 16.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EGB02002.1 - 0.011 15.2 0.4 0.02 14.4 0.4 1.4 1 0 0 1 1 1 0 EF hand DUF3665 PF12427.8 EGB02002.1 - 0.31 10.8 0.3 0.31 10.8 0.3 1.8 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase LRR_4 PF12799.7 EGB02003.1 - 1.1e-10 41.6 0.3 4.8e-05 23.6 0.4 2.8 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB02003.1 - 9.9e-10 38.2 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EGB02003.1 - 3.1e-05 23.6 1.8 0.0088 15.8 1.2 3.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 EGB02003.1 - 0.0023 17.8 3.9 0.016 15.2 0.0 3.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 EGB02003.1 - 0.16 12.6 3.7 23 6.1 0.0 3.8 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 EGB02005.1 - 6.8e-06 26.3 0.7 0.22 12.0 0.0 3.4 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB02005.1 - 0.0015 18.3 0.1 0.024 14.4 0.0 2.6 2 2 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 EGB02005.1 - 0.023 15.2 0.3 13 6.8 0.0 4.1 2 2 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 EGB02005.1 - 0.52 10.5 1.9 15 6.0 0.0 3.9 5 0 0 5 5 5 0 Leucine Rich repeat Amidase PF01425.21 EGB02006.1 - 2.8e-47 161.7 0.6 4.8e-47 161.0 0.6 1.3 1 1 0 1 1 1 1 Amidase HEAT PF02985.22 EGB02006.1 - 0.083 13.2 0.1 0.26 11.6 0.1 1.9 1 0 0 1 1 1 0 HEAT repeat zf-MYND PF01753.18 EGB02008.1 - 3e-09 36.8 17.8 3e-09 36.8 17.8 1.8 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EGB02008.1 - 2.8 8.3 10.4 7 7.1 10.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Gal-3-0_sulfotr PF06990.11 EGB02010.1 - 0.032 13.1 0.0 0.055 12.3 0.0 1.4 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase zf-ribbon_3 PF13248.6 EGB02011.1 - 0.00034 19.9 1.7 0.00087 18.6 1.7 1.7 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EGB02011.1 - 0.017 15.1 0.2 0.034 14.2 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon PPP4R2 PF09184.11 EGB02011.1 - 5.9 6.4 23.1 13 5.3 23.1 1.5 1 0 0 1 1 1 0 PPP4R2 Paf1 PF03985.13 EGB02011.1 - 8.1 5.3 19.2 13 4.6 19.2 1.3 1 0 0 1 1 1 0 Paf1 P2X_receptor PF00864.19 EGB02012.1 - 7.1e-09 35.2 0.1 1.3e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 ATP P2X receptor Caroten_synth PF04240.12 EGB02012.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Carotenoid biosynthesis protein PDDEXK_7 PF04411.12 EGB02015.1 - 0.022 14.7 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily CAP_N PF01213.19 EGB02015.1 - 2.2 7.7 5.5 2.7 7.4 5.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EF-hand_7 PF13499.6 EGB02016.1 - 0.095 13.2 0.5 0.29 11.6 0.5 2.0 1 1 0 1 1 1 0 EF-hand domain pair Nop25 PF09805.9 EGB02016.1 - 0.25 11.8 13.2 0.37 11.2 13.2 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4407 PF14362.6 EGB02016.1 - 0.62 9.4 11.6 0.75 9.1 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) R3H PF01424.22 EGB02017.1 - 2.4e-10 40.3 0.0 4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 R3H domain Mob1_phocein PF03637.17 EGB02018.1 - 9.1e-15 55.1 0.2 1e-14 54.9 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Peptidase_M17 PF00883.21 EGB02019.1 - 8.4e-96 320.9 0.3 9.2e-96 320.8 0.3 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3742 PF12553.8 EGB02020.1 - 0.63 10.2 0.0 0.63 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) HemY_N PF07219.13 EGB02020.1 - 1.1 9.5 7.4 0.56 10.4 0.5 2.5 2 0 0 2 2 2 0 HemY protein N-terminus KASH_CCD PF14662.6 EGB02021.1 - 0.038 13.8 10.4 0.72 9.6 1.5 2.5 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 EGB02021.1 - 0.06 12.6 21.2 0.11 11.8 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) MbeD_MobD PF04899.12 EGB02021.1 - 0.068 13.3 1.5 10 6.3 0.2 2.8 2 0 0 2 2 2 0 MbeD/MobD like zf-C4H2 PF10146.9 EGB02021.1 - 0.47 10.7 1.6 0.66 10.2 0.2 1.8 1 1 0 2 2 2 0 Zinc finger-containing protein PT PF04886.12 EGB02023.1 - 0.17 11.5 19.4 0.4 10.2 19.4 1.6 1 1 0 1 1 1 0 PT repeat AhpC-TSA PF00578.21 EGB02024.1 - 0.00022 21.1 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Hemerythrin PF01814.23 EGB02024.1 - 0.037 14.7 12.0 0.036 14.7 10.2 1.8 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Citrate_synt PF00285.21 EGB02026.1 - 1.6e-11 43.9 0.1 9.4e-09 34.8 0.1 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EGB02026.1 - 2e-09 37.4 0.0 3.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EGB02026.1 - 3.3e-05 24.5 0.0 9.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Rieske PF00355.26 EGB02027.1 - 2.6e-09 36.9 0.0 3.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Sulfotransfer_3 PF13469.6 EGB02028.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family zf-CCCH PF00642.24 EGB02028.1 - 0.096 12.6 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Aminotran_1_2 PF00155.21 EGB02029.1 - 1.4e-38 133.1 0.0 1.5e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGB02029.1 - 4.4e-05 22.2 0.0 6.2e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGB02029.1 - 0.0047 16.2 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SIP1 PF04938.12 EGB02030.1 - 2.5e-23 83.0 0.0 2.8e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF4589 PF15252.6 EGB02030.1 - 0.072 13.1 0.3 0.1 12.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) CENP-B_dimeris PF09026.10 EGB02030.1 - 0.18 12.2 6.8 0.3 11.5 6.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_transf_8 PF01501.20 EGB02031.1 - 7.5e-24 84.7 0.0 1e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Acyltransferase PF01553.21 EGB02032.1 - 0.0089 15.7 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase FG-GAP_2 PF14312.6 EGB02033.1 - 1.4e-32 111.7 95.3 8.2e-05 22.8 6.0 8.3 8 0 0 8 8 8 8 FG-GAP repeat HTH_43 PF09904.9 EGB02033.1 - 1.5e-06 28.0 18.2 1.2 9.1 0.1 6.8 7 0 0 7 7 7 4 Winged helix-turn helix Kelch_1 PF01344.25 EGB02033.1 - 0.0001 21.8 7.2 12 5.5 0.0 6.3 6 0 0 6 6 6 2 Kelch motif PD40 PF07676.12 EGB02033.1 - 0.002 18.0 2.8 1.6e+02 2.4 0.0 6.9 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat CE2_N PF17996.1 EGB02033.1 - 0.0022 18.0 9.0 4.8 7.2 0.0 6.6 7 1 1 8 8 8 1 Carbohydrate esterase 2 N-terminal PFU PF09070.11 EGB02033.1 - 0.083 13.2 16.9 69 3.7 0.1 6.8 7 0 0 7 7 7 0 PFU (PLAA family ubiquitin binding) Lsr2 PF11774.8 EGB02033.1 - 0.11 12.6 26.2 23 5.2 0.2 7.8 8 0 0 8 8 8 0 Lsr2 Ran_BP1 PF00638.18 EGB02033.1 - 0.65 10.3 4.8 31 4.9 0.0 5.0 7 0 0 7 7 7 0 RanBP1 domain F-box-like PF12937.7 EGB02034.1 - 4e-06 26.6 0.1 2.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGB02034.1 - 0.00089 19.1 0.2 0.0023 17.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGB02034.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 F-box TUDOR_5 PF18359.1 EGB02035.1 - 6.3e-40 134.7 59.5 0.0001 21.9 0.4 10.6 10 0 0 10 10 10 9 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 EGB02035.1 - 2.8e-37 126.3 22.9 0.0038 17.0 0.1 10.0 10 0 0 10 10 10 9 DNA repair protein Crb2 Tudor domain 53-BP1_Tudor PF09038.10 EGB02035.1 - 1.2e-34 118.9 33.6 0.0049 16.8 0.1 10.1 10 0 0 10 10 10 9 Tumour suppressor p53-binding protein-1 Tudor Agenet PF05641.12 EGB02035.1 - 3.7e-25 88.1 48.5 0.041 14.3 0.9 10.0 11 0 0 11 11 11 9 Agenet domain DUF4537 PF15057.6 EGB02035.1 - 2.7e-24 85.5 16.9 9.3e-05 22.4 0.2 6.3 2 1 4 7 7 7 7 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 EGB02035.1 - 1.9e-18 66.0 47.2 0.033 14.0 0.4 9.7 10 0 0 10 10 10 9 Lamin-B receptor of TUDOR domain LPD30 PF18850.1 EGB02035.1 - 2.6e-10 40.1 0.0 19 5.0 0.0 8.4 10 0 0 10 10 10 0 Large polyvalent protein associated domain 30 Tcp10_C PF07202.13 EGB02035.1 - 0.002 18.1 105.0 0.94 9.4 2.8 10.1 10 0 0 10 10 10 8 T-complex protein 10 C-terminus DUF4772 PF15997.5 EGB02035.1 - 0.0037 17.8 9.4 64 4.2 0.0 7.7 4 2 6 10 10 10 0 Domain of unknown function (DUF4772) 4_1_CTD PF05902.13 EGB02035.1 - 0.015 15.4 17.8 1.2e+02 2.8 0.1 8.1 8 0 0 8 8 8 0 4.1 protein C-terminal domain (CTD) EFP_N PF08207.12 EGB02035.1 - 0.22 11.6 15.2 1.2e+02 2.8 0.0 8.5 10 0 0 10 10 10 0 Elongation factor P (EF-P) KOW-like domain DIOX_N PF14226.6 EGB02036.1 - 2.3e-08 34.8 0.0 3.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGB02036.1 - 1.6e-07 31.7 0.0 2.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Latarcin PF10279.9 EGB02037.1 - 0.059 13.8 0.5 0.084 13.3 0.5 1.3 1 0 0 1 1 1 0 Latarcin precursor zf-RING_4 PF14570.6 EGB02040.1 - 3.8e-09 36.2 7.7 5.3e-09 35.7 7.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGB02040.1 - 6.2e-07 29.2 5.3 8.5e-07 28.7 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB02040.1 - 1.3e-06 28.6 6.8 1.8e-06 28.2 6.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB02040.1 - 0.0028 17.5 6.9 0.0059 16.4 6.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB02040.1 - 0.016 15.1 5.1 0.025 14.5 5.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGB02040.1 - 0.022 14.6 5.2 0.032 14.1 5.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB02040.1 - 0.031 14.3 2.0 0.053 13.6 2.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EGB02040.1 - 0.062 13.2 3.9 0.13 12.1 3.9 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGB02040.1 - 0.14 12.0 2.6 0.25 11.1 2.6 1.4 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_1 PF14446.6 EGB02040.1 - 2.5 8.1 9.3 0.59 10.1 3.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF285 PF03382.14 EGB02042.1 - 0.0045 16.7 0.3 0.015 15.0 0.3 1.8 1 1 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 UCH PF00443.29 EGB02043.1 - 3.5e-22 79.2 0.0 4.2e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB02043.1 - 0.00018 21.2 0.0 0.00026 20.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGB02043.1 - 0.066 12.7 0.3 5.2 6.5 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ank_2 PF12796.7 EGB02044.1 - 8.9e-21 74.3 0.1 2.1e-14 53.9 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB02044.1 - 1.3e-18 65.1 0.8 7.5e-05 22.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGB02044.1 - 4e-17 62.1 4.1 9.4e-06 25.8 0.3 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB02044.1 - 4.4e-15 55.8 0.4 1.1e-07 32.3 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB02044.1 - 1.3e-14 53.9 7.6 0.00055 20.3 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Arylsulfotrans PF05935.11 EGB02045.1 - 0.0025 16.8 0.0 0.0035 16.3 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB02045.1 - 0.0025 17.2 0.1 0.0033 16.8 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Ank_2 PF12796.7 EGB02046.1 - 7e-20 71.4 0.0 8.3e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB02046.1 - 2.9e-17 62.5 0.1 2.4e-09 37.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB02046.1 - 2.6e-15 56.6 0.0 6.8e-06 26.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB02046.1 - 1.8e-14 52.4 0.3 0.00036 20.7 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGB02046.1 - 5e-13 48.9 0.1 2e-06 28.0 0.0 3.9 4 1 0 4 4 4 2 Ankyrin repeat OTU PF02338.19 EGB02047.1 - 5.6e-07 30.1 0.0 7.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease SH3_3 PF08239.11 EGB02049.1 - 0.0004 20.6 0.0 0.00094 19.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 EGB02049.1 - 0.049 13.5 0.3 0.089 12.6 0.3 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_3 PF08239.11 EGB02050.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Hydrolase_like PF13242.6 EGB02052.1 - 0.00023 21.2 0.9 0.00028 20.9 0.9 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGB02052.1 - 0.0052 16.9 0.1 0.0063 16.6 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3377 PF11857.8 EGB02053.1 - 0.011 15.7 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3357 PF11837.8 EGB02053.1 - 0.19 12.2 0.5 0.26 11.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) SNF5 PF04855.12 EGB02054.1 - 0.0011 18.8 0.0 0.0014 18.5 0.0 1.3 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Mpp10 PF04006.12 EGB02054.1 - 0.0031 16.0 6.5 0.083 11.3 0.0 2.7 3 0 0 3 3 3 2 Mpp10 protein cNMP_binding PF00027.29 EGB02055.1 - 0.0011 19.0 0.1 0.0017 18.4 0.1 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SERTA PF06031.13 EGB02055.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 SERTA motif DUF4846 PF16138.5 EGB02055.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (4846) TPH PF13868.6 EGB02060.1 - 2.7e-10 39.3 68.8 2.7e-10 39.3 68.8 1.7 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain VCBS PF13517.6 EGB02061.1 - 1.5e-14 54.3 20.3 0.087 13.4 0.3 6.6 1 1 5 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella KOW PF00467.29 EGB02061.1 - 0.0025 17.7 0.2 0.006 16.5 0.2 1.6 1 0 0 1 1 1 1 KOW motif SNAP PF14938.6 EGB02061.1 - 0.58 9.5 8.0 8.7 5.7 0.0 4.1 3 3 1 4 4 4 0 Soluble NSF attachment protein, SNAP PmoA PF14100.6 EGB02061.1 - 1.7 8.1 9.4 13 5.2 0.1 3.8 2 2 2 4 4 4 0 Methane oxygenase PmoA TPR_11 PF13414.6 EGB02061.1 - 9.3 6.0 18.7 88 2.9 0.1 6.1 6 0 0 6 6 6 0 TPR repeat TRAPP PF04051.16 EGB02063.1 - 5.5e-35 120.2 0.1 6.6e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Mpv17_PMP22 PF04117.12 EGB02066.1 - 2.8e-12 46.7 0.1 5e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Sulf_transp PF04143.14 EGB02066.1 - 0.0055 16.3 0.6 0.0092 15.6 0.5 1.5 1 1 1 2 2 2 1 Sulphur transport AIM5 PF17050.5 EGB02068.1 - 0.04 14.7 0.0 0.076 13.8 0.0 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 EGF_2 PF07974.13 EGB02070.1 - 0.00025 21.4 8.9 0.00049 20.4 8.9 1.5 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 EGB02070.1 - 0.018 15.2 4.4 0.037 14.2 4.4 1.4 1 0 0 1 1 1 0 Laminin EGF domain S_locus_glycop PF00954.20 EGB02070.1 - 0.089 13.3 3.2 0.2 12.2 3.2 1.6 1 0 0 1 1 1 0 S-locus glycoprotein domain T2SSM PF04612.12 EGB02071.1 - 0.042 13.9 3.9 0.66 10.0 0.5 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Cep57_CLD_2 PF14197.6 EGB02071.1 - 0.25 11.5 3.1 3.8 7.7 0.8 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF3618 PF12277.8 EGB02071.1 - 7.5 6.9 10.4 1.9 8.8 4.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) TTL PF03133.15 EGB02074.1 - 3.1e-20 72.5 0.0 3.5e-19 69.0 0.0 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Hexapep PF00132.24 EGB02074.1 - 1.4e-05 24.6 9.2 2.1e-05 24.0 2.5 3.1 4 0 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB02074.1 - 0.00012 21.8 8.0 0.24 11.2 0.1 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Methyltransf_23 PF13489.6 EGB02075.1 - 0.0015 18.4 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02075.1 - 0.002 18.8 0.4 0.0044 17.7 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB02075.1 - 0.064 14.0 0.1 0.22 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGB02075.1 - 0.074 13.7 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rad51 PF08423.11 EGB02076.1 - 5.9e-05 22.4 0.0 7.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Rad51 Sel1 PF08238.12 EGB02077.1 - 7.5e-19 67.8 1.9 3.6e-07 30.6 0.1 4.3 4 0 0 4 4 4 4 Sel1 repeat ANTAR PF03861.14 EGB02077.1 - 0.0072 16.1 0.4 0.11 12.4 0.1 2.3 2 0 0 2 2 2 1 ANTAR domain TPR_14 PF13428.6 EGB02077.1 - 0.014 16.2 1.8 0.66 11.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 EGB02077.1 - 0.032 14.1 2.8 0.06 13.2 2.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGB02077.1 - 0.08 12.8 2.9 0.15 11.9 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EGB02077.1 - 0.1 12.7 1.1 0.18 11.9 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon AAA_5 PF07728.14 EGB02078.1 - 1e-25 90.4 0.0 5.1e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EGB02078.1 - 5.8e-05 23.3 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_22 PF13401.6 EGB02078.1 - 0.00014 22.2 0.1 0.0011 19.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGB02078.1 - 0.00036 20.1 0.0 0.0015 18.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 EGB02078.1 - 0.0011 18.9 0.0 0.083 12.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGB02078.1 - 0.0099 15.6 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGB02078.1 - 0.014 15.8 6.2 0.054 13.9 0.1 3.7 3 1 1 4 4 4 0 AAA ATPase domain AAA PF00004.29 EGB02078.1 - 0.017 15.5 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EGB02078.1 - 0.029 14.5 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGB02078.1 - 0.05 13.6 0.0 20 5.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_6 PF12774.7 EGB02078.1 - 0.077 11.9 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region CbbQ_C PF08406.10 EGB02078.1 - 0.11 12.8 2.1 0.11 12.7 0.3 2.1 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal PAS_8 PF13188.7 EGB02079.1 - 0.087 12.9 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 PAS domain ABC_membrane PF00664.23 EGB02081.1 - 0.071 12.7 0.1 0.086 12.5 0.1 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region Sel1 PF08238.12 EGB02082.1 - 2e-24 85.5 10.9 4.1e-10 40.0 0.1 4.6 4 1 0 4 4 4 3 Sel1 repeat TPR_12 PF13424.6 EGB02082.1 - 0.00072 19.8 5.2 0.073 13.4 0.3 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02082.1 - 0.0049 16.7 4.2 1.5 8.8 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02082.1 - 0.034 14.0 0.4 0.034 14.0 0.4 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02082.1 - 0.055 13.6 15.9 0.18 12.0 0.8 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02082.1 - 0.3 11.2 6.5 10 6.4 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02082.1 - 0.87 10.0 7.7 2.3 8.6 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat His_Phos_1 PF00300.22 EGB02083.1 - 2.5e-11 43.7 1.6 1.5e-06 28.1 0.8 3.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) HD PF01966.22 EGB02086.1 - 7.3e-10 39.1 0.1 1.3e-09 38.3 0.1 1.5 1 1 0 1 1 1 1 HD domain PDEase_I PF00233.19 EGB02086.1 - 0.004 16.9 0.3 0.006 16.3 0.3 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TRP PF06011.12 EGB02087.1 - 2.4e-08 33.2 4.1 3.6e-08 32.6 4.1 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Stc1 PF12898.7 EGB02088.1 - 0.0009 19.8 0.1 0.0012 19.3 0.1 1.2 1 0 0 1 1 1 1 Stc1 domain Zn_Tnp_IS1595 PF12760.7 EGB02088.1 - 0.2 11.7 1.0 0.33 11.0 1.0 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DEAD PF00270.29 EGB02089.1 - 4.2e-34 117.8 0.0 6.1e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB02089.1 - 2.4e-25 89.0 0.0 3.8e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB02089.1 - 0.0074 16.3 0.0 0.0098 15.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGB02089.1 - 0.2 11.9 0.1 2.4 8.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain Glyoxalase PF00903.25 EGB02090.1 - 3.7e-21 75.6 0.0 4.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGB02090.1 - 5e-08 33.7 0.0 1.7e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EGB02090.1 - 2.3e-05 24.6 0.0 0.0017 18.6 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGB02090.1 - 0.15 12.1 0.0 5.5 7.1 0.0 2.6 2 1 1 3 3 3 0 Glyoxalase-like domain Aldedh PF00171.22 EGB02091.1 - 6.6e-18 64.5 0.0 7.7e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Nuc_sug_transp PF04142.15 EGB02094.1 - 5.6e-17 61.9 8.2 6.1e-17 61.8 8.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB02094.1 - 0.0046 17.1 5.5 0.0052 17.0 5.5 1.0 1 0 0 1 1 1 1 EamA-like transporter family LRR_6 PF13516.6 EGB02095.1 - 9.9e-11 40.8 8.8 0.013 15.5 0.0 6.4 6 0 0 6 6 6 4 Leucine Rich repeat LRR_8 PF13855.6 EGB02095.1 - 0.00015 21.5 0.2 0.75 9.6 0.0 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EGB02095.1 - 0.00068 19.8 0.0 14 6.7 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 EGB02095.1 - 0.027 14.9 3.7 3.9 8.0 0.0 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF21 PF01595.20 EGB02095.1 - 0.038 13.7 1.3 0.065 12.9 1.3 1.3 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Gly-zipper_YMGG PF13441.6 EGB02096.1 - 4.1 7.2 5.2 30 4.4 0.4 2.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper PLAC8 PF04749.17 EGB02097.1 - 9.4e-11 42.6 8.1 1.4e-10 42.1 8.1 1.2 1 0 0 1 1 1 1 PLAC8 family DAGAT PF03982.13 EGB02098.1 - 2.8e-22 79.0 0.0 3.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase ApoO PF09769.9 EGB02099.1 - 0.042 13.8 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O Sel1 PF08238.12 EGB02100.1 - 4.3e-19 68.5 9.3 7.2e-10 39.2 0.2 4.6 4 1 0 4 4 4 4 Sel1 repeat TPR_2 PF07719.17 EGB02100.1 - 0.0015 18.5 7.2 1.6 9.1 2.9 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02100.1 - 0.0039 17.9 2.5 0.79 10.7 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02100.1 - 0.036 13.9 7.5 0.93 9.4 2.3 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3598 PF12204.8 EGB02101.1 - 0.00015 21.3 4.5 0.13 11.7 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3598) RimM PF01782.18 EGB02102.1 - 0.0073 16.5 0.0 6.2 7.1 0.0 2.3 2 0 0 2 2 2 2 RimM N-terminal domain Acetyltransf_6 PF13480.7 EGB02102.1 - 0.17 12.1 4.7 1.4 9.1 0.1 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Laminin_G_3 PF13385.6 EGB02103.1 - 1.3e-92 307.9 42.3 2.1e-23 83.1 4.7 5.3 5 0 0 5 5 5 5 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EGB02103.1 - 4.5e-11 43.4 3.7 0.37 11.4 0.0 5.4 5 0 0 5 5 5 4 Laminin G domain Pentaxin PF00354.17 EGB02103.1 - 4.6e-10 39.5 1.2 0.017 14.9 0.0 6.2 6 2 0 6 6 6 3 Pentaxin family Chlorovi_GP_rpt PF06598.11 EGB02103.1 - 1.2e-05 25.3 0.0 10 6.2 0.0 4.7 4 0 0 4 4 4 2 Chlorovirus glycoprotein repeat SGT1 PF07093.11 EGB02104.1 - 0.0055 15.2 2.3 0.0059 15.1 2.3 1.0 1 0 0 1 1 1 1 SGT1 protein GCIP PF13324.6 EGB02104.1 - 0.02 14.5 2.6 0.029 14.0 2.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4407 PF14362.6 EGB02104.1 - 0.33 10.2 9.6 0.43 9.9 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIF4G_like_2 PF09090.11 EGB02104.1 - 0.55 9.6 2.5 0.6 9.5 2.5 1.2 1 0 0 1 1 1 0 MIF4G like RRN3 PF05327.11 EGB02104.1 - 1.2 7.6 4.7 1.4 7.4 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_2 PF07719.17 EGB02106.1 - 5.8e-18 63.5 3.6 0.00017 21.4 0.0 4.5 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGB02106.1 - 1.9e-17 62.3 0.4 1.2e-05 25.3 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02106.1 - 2.2e-16 60.2 9.5 5.2e-07 30.2 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB02106.1 - 1.1e-15 57.0 3.2 4.9e-07 29.3 0.0 4.6 3 1 2 5 5 5 2 TPR repeat TPR_1 PF00515.28 EGB02106.1 - 4.4e-15 54.8 2.2 0.032 14.0 0.0 4.7 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02106.1 - 5.7e-12 45.4 1.9 0.004 17.8 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB02106.1 - 7.3e-11 42.4 2.7 9.7e-05 22.8 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB02106.1 - 8.5e-10 38.8 5.3 0.0019 18.4 0.9 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02106.1 - 1.4e-08 34.2 2.8 2.8 8.4 0.1 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 EGB02106.1 - 5.3e-07 29.6 1.7 0.48 11.2 0.5 4.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02106.1 - 8.7e-07 28.6 1.3 5.3 7.3 0.0 4.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB02106.1 - 1.9e-05 24.7 0.5 0.0049 17.0 0.0 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02106.1 - 4.2e-05 23.9 0.6 9.4 7.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02106.1 - 0.00057 19.7 5.8 1.4 8.9 0.0 4.6 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB02106.1 - 0.0098 16.1 0.2 2.7 8.3 0.0 2.8 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGB02106.1 - 0.023 14.1 0.1 0.087 12.2 0.0 1.8 1 1 1 2 2 2 0 MalT-like TPR region BTAD PF03704.17 EGB02106.1 - 0.069 13.6 0.6 0.14 12.6 0.3 1.5 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_15 PF13429.6 EGB02106.1 - 0.07 12.3 0.1 3.6 6.7 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGB02106.1 - 0.3 11.1 2.5 5.8 7.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Voltage_CLC PF00654.20 EGB02107.1 - 2e-31 109.5 14.1 2.7e-31 109.1 14.1 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EGB02107.1 - 0.0053 17.2 0.1 0.99 9.9 0.0 2.6 2 0 0 2 2 2 1 CBS domain YabA PF06156.13 EGB02107.1 - 0.012 16.2 4.8 3 8.6 0.2 3.0 2 1 1 3 3 3 0 Initiation control protein YabA DUF4407 PF14362.6 EGB02107.1 - 0.33 10.2 9.3 0.89 8.9 9.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2353 PF09789.9 EGB02107.1 - 1.4 8.2 6.3 2.3 7.5 6.3 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) bZIP_1 PF00170.21 EGB02107.1 - 3.6 7.8 6.2 6 7.0 0.2 2.8 3 0 0 3 3 3 0 bZIP transcription factor HALZ PF02183.18 EGB02107.1 - 5.2 7.4 11.7 0.14 12.4 0.7 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 EGB02107.1 - 7.9 6.7 10.0 9.3 6.4 0.7 3.0 3 0 0 3 3 3 0 Basic region leucine zipper Abhydrolase_6 PF12697.7 EGB02108.1 - 4e-11 43.9 19.2 5.7e-11 43.4 19.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB02108.1 - 9.4e-08 32.0 0.7 1.2e-07 31.7 0.7 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB02108.1 - 4e-06 26.3 3.6 7.1e-06 25.5 3.6 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGB02108.1 - 0.014 15.0 0.1 0.02 14.5 0.1 1.4 1 1 0 1 1 1 0 Putative esterase Trehalose_PPase PF02358.16 EGB02109.1 - 2.5e-34 118.4 0.0 3.4e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase S6PP PF05116.13 EGB02109.1 - 2.1e-05 24.2 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 EGB02109.1 - 2.2e-05 24.4 0.0 5.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 EGB02111.1 - 2.2e-20 73.1 0.0 2.4e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB02111.1 - 7.9e-19 68.0 0.0 8.4e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGB02111.1 - 0.17 11.2 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGB02111.1 - 0.19 11.3 0.0 8.3 6.0 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glyco_transf_8 PF01501.20 EGB02112.1 - 7.2e-18 65.1 0.0 9e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Lyase_1 PF00206.20 EGB02113.1 - 6.2e-45 153.9 0.0 7.7e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Lyase Methyltransf_23 PF13489.6 EGB02114.1 - 5.5e-08 32.8 0.0 7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02114.1 - 7.6e-08 33.0 0.1 1.8e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB02114.1 - 1.3e-06 28.9 0.2 3.4e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB02114.1 - 3.7e-05 24.4 0.0 6.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02114.1 - 0.019 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EGB02114.1 - 0.079 12.4 0.0 0.34 10.3 0.0 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB Gtr1_RagA PF04670.12 EGB02118.1 - 9e-21 74.3 0.0 1e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB02118.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB02118.1 - 0.0029 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGB02118.1 - 0.028 14.6 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EGB02118.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 EGB02118.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain BCAS2 PF05700.11 EGB02119.1 - 2.8e-33 115.4 0.1 3.6e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) EF-hand_1 PF00036.32 EGB02121.1 - 9.7e-09 34.2 0.0 0.0046 16.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB02121.1 - 1.3e-08 34.1 0.2 0.0011 18.7 0.0 3.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EGB02121.1 - 8.5e-08 31.4 0.2 0.0025 17.2 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB02121.1 - 1.6e-05 25.2 0.0 0.00043 20.7 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB02121.1 - 0.0037 17.1 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair Drf_FH3 PF06367.16 EGB02122.1 - 8.5e-08 32.0 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Diaphanous FH3 Domain TTL PF03133.15 EGB02123.1 - 5.4e-26 91.4 0.0 7.4e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB02123.1 - 7.7e-06 25.3 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGB02123.1 - 0.0047 16.2 0.0 0.0066 15.7 0.0 1.1 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HIP1_clath_bdg PF16515.5 EGB02128.1 - 0.045 14.4 0.0 3 8.5 0.0 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Plasmid_RAQPRD PF09686.10 EGB02128.1 - 0.13 12.5 1.2 0.63 10.3 0.0 2.5 2 1 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TPR_2 PF07719.17 EGB02129.1 - 0.00052 19.9 1.7 0.16 12.1 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02129.1 - 0.0021 18.7 3.8 0.14 13.1 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 EGB02129.1 - 0.056 13.9 2.7 1 9.8 2.7 2.1 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 EGB02129.1 - 0.12 12.2 0.2 1.9 8.4 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB02129.1 - 0.23 11.8 5.9 0.58 10.5 0.8 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02129.1 - 0.67 10.7 6.3 15 6.3 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3523 PF12037.8 EGB02130.1 - 2.4e-06 27.1 18.6 2.9e-06 26.9 18.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) DUF778 PF05608.12 EGB02130.1 - 0.018 15.4 1.4 0.018 15.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Methyltransf_23 PF13489.6 EGB02131.1 - 1.1e-15 57.8 0.0 2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB02131.1 - 1.8e-12 47.8 0.0 8.3e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB02131.1 - 4.1e-12 46.7 0.0 5.3e-11 43.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02131.1 - 7.6e-11 42.6 0.0 6.3e-09 36.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02131.1 - 6.9e-08 32.4 0.0 0.00098 18.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain NodS PF05401.11 EGB02131.1 - 0.0097 15.5 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) CheR PF01739.18 EGB02131.1 - 0.024 14.1 0.0 0.097 12.1 0.0 1.9 2 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 EGB02131.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family NAD_binding_10 PF13460.6 EGB02133.1 - 3.1e-10 40.3 0.7 5.7e-10 39.4 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGB02133.1 - 1e-09 37.8 0.0 1.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGB02133.1 - 1.5e-08 34.4 0.1 2.4e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-MYND PF01753.18 EGB02133.1 - 7.4e-07 29.1 7.3 7.4e-07 29.1 7.3 1.9 2 0 0 2 2 2 1 MYND finger NAD_binding_4 PF07993.12 EGB02133.1 - 4.2e-06 26.1 0.1 5.2e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGB02133.1 - 2.2e-05 24.0 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGB02133.1 - 0.00011 21.9 0.4 0.00019 21.0 0.4 1.4 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EGB02133.1 - 0.022 13.9 0.1 0.035 13.2 0.1 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PAC2 PF09754.9 EGB02133.1 - 0.031 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 PAC2 family Ecl1 PF12855.7 EGB02133.1 - 0.26 12.4 1.4 0.37 11.9 1.4 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins FTHFS PF01268.19 EGB02135.1 - 6.5e-39 133.6 0.0 7.1e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Gly_rich_SFCGS PF14272.6 EGB02135.1 - 0.067 13.2 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Glycine-rich SFCGS Arm PF00514.23 EGB02136.1 - 4.7e-42 140.8 9.1 5.5e-10 38.9 0.0 5.0 5 0 0 5 5 5 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB02136.1 - 7.2e-09 35.9 15.2 8.7e-05 22.8 2.7 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 EGB02136.1 - 8.8e-08 32.5 14.5 0.00012 22.5 1.7 4.3 3 1 2 5 5 5 3 HEAT-like repeat Arm_2 PF04826.13 EGB02136.1 - 4.7e-07 29.5 0.0 0.027 14.0 0.0 2.9 1 1 2 3 3 3 3 Armadillo-like HEAT PF02985.22 EGB02136.1 - 1.3e-06 28.2 8.1 1.2 9.6 0.1 4.7 5 0 0 5 5 4 3 HEAT repeat Cnd1 PF12717.7 EGB02136.1 - 6e-05 23.1 0.1 0.084 12.9 0.0 2.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 EGB02136.1 - 0.00044 20.2 0.2 0.016 15.2 0.0 2.5 2 1 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain RICTOR_N PF14664.6 EGB02136.1 - 0.0037 16.3 0.1 9.6 5.1 0.0 3.4 1 1 3 4 4 4 1 Rapamycin-insensitive companion of mTOR, N-term PUL PF08324.11 EGB02136.1 - 0.015 14.6 2.5 0.021 14.1 2.5 1.4 1 1 0 1 1 1 0 PUL domain IPT PF01745.16 EGB02136.1 - 0.018 14.5 0.0 5.1 6.4 0.0 2.4 1 1 0 2 2 2 0 Isopentenyl transferase Aconitase_B_N PF11791.8 EGB02136.1 - 0.045 13.8 1.7 54 3.8 0.0 3.9 1 1 2 4 4 4 0 Aconitate B N-terminal domain Tetradecapep PF08187.11 EGB02136.1 - 0.083 13.0 1.6 25 5.2 0.3 3.6 3 0 0 3 3 3 0 Myoactive tetradecapeptides family ALF PF03752.13 EGB02136.1 - 0.085 12.8 14.5 2 8.5 0.3 4.5 4 0 0 4 4 4 0 Short repeats of unknown function HEAT_PBS PF03130.16 EGB02136.1 - 0.09 13.5 13.1 1.2 10.0 0.7 5.0 4 3 0 4 4 4 0 PBS lyase HEAT-like repeat V-ATPase_H_N PF03224.14 EGB02136.1 - 0.15 11.3 0.0 0.74 9.0 0.0 2.0 1 1 0 1 1 1 0 V-ATPase subunit H IFRD PF05004.13 EGB02136.1 - 0.16 11.0 1.1 0.8 8.8 1.1 2.2 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Rsa3 PF14615.6 EGB02136.1 - 0.21 11.2 1.5 49 3.6 0.0 3.9 5 0 0 5 5 5 0 Ribosome-assembly protein 3 Proteasome_A_N PF10584.9 EGB02137.1 - 8.6e-15 54.1 0.0 1.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Proteasome PF00227.26 EGB02137.1 - 0.0024 17.4 0.3 0.0033 17.0 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit C2 PF00168.30 EGB02139.1 - 3.9e-05 23.9 0.0 0.00013 22.2 0.0 1.9 2 0 0 2 2 2 1 C2 domain Ion_trans_2 PF07885.16 EGB02143.1 - 1.9e-10 40.5 1.4 3e-10 39.9 1.4 1.2 1 0 0 1 1 1 1 Ion channel DUF1515 PF07439.11 EGB02143.1 - 0.22 11.5 1.1 0.46 10.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) RSB_motif PF16294.5 EGB02143.1 - 3.4 8.0 5.8 0.98 9.7 0.2 2.1 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif TPR_14 PF13428.6 EGB02143.1 - 7.6 7.7 12.0 5 8.2 1.0 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat Asp_Arg_Hydrox PF05118.15 EGB02144.1 - 3.8e-40 137.3 0.1 4.3e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 EGB02144.1 - 0.038 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Cupin domain DEP PF00610.21 EGB02146.1 - 0.02 14.9 0.0 0.073 13.1 0.0 1.9 1 1 1 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) UCR_UQCRX_QCR9 PF05365.12 EGB02146.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like EAP30 PF04157.16 EGB02146.1 - 0.032 13.5 0.1 0.038 13.3 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family MBD PF01429.19 EGB02147.1 - 5.6e-06 26.0 0.0 8.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyl-CpG binding domain DDT PF02791.17 EGB02147.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 DDT domain RsgA_GTPase PF03193.16 EGB02148.1 - 1.5e-05 25.0 0.0 0.001 19.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGB02148.1 - 2.8e-05 24.6 0.0 4.2e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGB02148.1 - 6.4e-05 23.0 0.0 9.1e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 EGB02148.1 - 0.0002 20.6 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EGB02148.1 - 0.00031 20.1 0.2 0.0012 18.1 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin IIGP PF05049.13 EGB02148.1 - 0.0043 16.2 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 EGB02148.1 - 0.0069 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EGB02148.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_33 PF13671.6 EGB02148.1 - 0.01 16.0 0.0 0.042 14.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB02148.1 - 0.012 16.1 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EGB02148.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EGB02148.1 - 0.016 15.6 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGB02148.1 - 0.024 14.7 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AIG1 PF04548.16 EGB02148.1 - 0.024 13.9 0.0 0.082 12.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family AAA_19 PF13245.6 EGB02148.1 - 0.028 14.8 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB02148.1 - 0.03 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB02148.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGB02148.1 - 0.041 14.3 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EGB02148.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PPV_E1_C PF00519.17 EGB02148.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_23 PF13476.6 EGB02148.1 - 0.29 11.6 0.0 0.29 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 EGB02150.1 - 0.001 19.7 8.3 0.001 19.7 8.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EGB02150.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.8 EGB02150.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB02150.1 - 0.03 14.0 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SET PF00856.28 EGB02151.1 - 0.018 15.4 0.0 0.62 10.4 0.0 2.1 1 1 0 1 1 1 0 SET domain LSM PF01423.22 EGB02152.1 - 9.7e-17 60.4 0.0 1.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGB02152.1 - 2.8e-06 27.4 0.0 3.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain FtsJ PF01728.19 EGB02153.1 - 5.4e-49 166.7 0.0 6.6e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase E1-N PF14463.6 EGB02153.1 - 0.0025 17.7 2.1 0.0034 17.2 2.1 1.2 1 0 0 1 1 1 1 E1 N-terminal domain Methyltr_RsmB-F PF01189.17 EGB02153.1 - 0.036 13.7 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F NAD_binding_8 PF13450.6 EGB02154.1 - 4.2e-10 39.7 0.2 7.4e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGB02154.1 - 0.054 12.5 0.1 0.069 12.2 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 EGB02154.1 - 0.063 12.6 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGB02154.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF4824 PF16106.5 EGB02155.1 - 0.11 11.8 3.9 0.15 11.3 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) SNF2_N PF00176.23 EGB02156.1 - 8.4e-29 100.4 0.0 2.3e-28 98.9 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Fringe PF02434.16 EGB02156.1 - 2e-07 30.7 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DEAD PF00270.29 EGB02156.1 - 0.24 11.1 0.0 5.2 6.8 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Histone PF00125.24 EGB02157.1 - 3.9e-16 59.6 0.5 4.8e-16 59.3 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB02157.1 - 0.0038 17.5 0.1 0.0098 16.2 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB02157.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A EMP70 PF02990.16 EGB02161.1 - 1.4e-34 119.7 0.1 1.7e-34 119.4 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 fn3 PF00041.21 EGB02162.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain DUF883 PF05957.13 EGB02164.1 - 0.051 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3730 PF12530.8 EGB02164.1 - 0.14 11.7 0.1 0.59 9.7 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3730) VCBS PF13517.6 EGB02166.1 - 0.00099 19.7 10.8 0.0067 17.0 2.4 2.5 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RRM_1 PF00076.22 EGB02167.1 - 1.9e-12 46.8 0.0 2.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 EGB02167.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF1690 PF07956.11 EGB02169.1 - 0.0012 19.3 0.1 0.0024 18.3 0.1 1.5 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) zf-MYND PF01753.18 EGB02170.1 - 1.7 8.8 24.5 0.056 13.5 18.1 1.9 2 0 0 2 2 2 0 MYND finger GSHPx PF00255.19 EGB02172.1 - 1.5e-17 63.1 0.0 2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 EGB02172.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 Redoxin PCRF PF03462.18 EGB02173.1 - 1.5e-32 113.0 0.0 2.5e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EGB02173.1 - 2.6e-28 98.3 0.0 4e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 RF-1 domain dsDNA_bind PF01984.20 EGB02175.1 - 2.7e-22 79.2 5.5 3e-22 79.0 5.5 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain L_lactis_RepB_C PF06430.12 EGB02175.1 - 1.2 9.2 5.1 1.3 9.1 0.3 2.0 1 1 1 2 2 2 0 Lactococcus lactis RepB C-terminus AFG1_ATPase PF03969.16 EGB02176.1 - 2.5e-53 181.3 0.0 3.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase AAA_14 PF13173.6 EGB02176.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGB02176.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EGB02176.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 EGB02176.1 - 0.063 13.7 1.8 0.39 11.1 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain EF-hand_6 PF13405.6 EGB02177.1 - 6.1e-08 32.0 2.7 0.0011 18.7 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB02177.1 - 1.2e-06 28.9 2.9 1.8e-06 28.3 2.9 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB02177.1 - 6.9e-06 25.3 4.3 8e-05 21.9 0.2 2.4 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB02177.1 - 0.0012 18.2 3.4 0.061 12.9 0.2 2.7 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB02177.1 - 0.094 12.6 3.4 0.26 11.2 0.2 2.0 2 0 0 2 2 2 0 EF-hand domain pair TPR_16 PF13432.6 EGB02179.1 - 3.5e-19 69.2 75.6 2.4e-07 31.3 9.3 5.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02179.1 - 2.9e-18 64.4 33.5 1e-05 25.2 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02179.1 - 1.4e-16 59.8 57.2 0.00011 22.7 0.5 8.5 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGB02179.1 - 4.7e-14 51.8 17.6 0.002 17.8 0.2 6.6 5 2 2 7 7 7 3 TPR repeat TPR_19 PF14559.6 EGB02179.1 - 3.5e-13 49.8 40.6 1.1e-05 25.8 0.4 5.6 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02179.1 - 5.6e-13 48.1 8.0 8.1e-06 25.4 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02179.1 - 2.4e-11 42.9 3.3 0.042 14.1 0.0 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB02179.1 - 5.8e-11 42.0 11.7 0.025 14.9 0.0 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB02179.1 - 1.7e-10 40.9 38.1 0.008 16.3 4.3 5.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGB02179.1 - 7.8e-08 32.5 40.0 0.00014 22.1 0.6 5.8 3 1 3 6 6 6 3 Tetratricopeptide repeat BTAD PF03704.17 EGB02179.1 - 1.4e-06 28.8 29.9 0.00065 20.2 0.2 4.6 3 1 1 4 4 4 2 Bacterial transcriptional activator domain TPR_6 PF13174.6 EGB02179.1 - 3.4e-05 24.2 23.7 0.026 15.2 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02179.1 - 0.0001 22.1 18.2 0.023 14.7 0.1 6.9 6 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB02179.1 - 0.0022 18.2 3.1 0.73 10.1 0.1 2.9 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EGB02179.1 - 0.0048 17.2 19.3 0.037 14.4 0.3 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02179.1 - 0.0068 16.2 42.0 0.1 12.5 0.4 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 EGB02179.1 - 0.045 14.4 96.1 0.09 13.4 5.0 9.4 10 0 0 10 10 8 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGB02179.1 - 1 9.5 7.4 4.6 7.3 0.7 3.1 2 2 0 2 2 2 0 Domain of Unknown Function (DUF3856) Mito_carr PF00153.27 EGB02181.1 - 3.6e-22 78.1 0.0 2.7e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein IQ PF00612.27 EGB02182.1 - 4.4e-05 22.9 7.0 0.46 10.4 0.0 3.6 3 0 0 3 3 3 3 IQ calmodulin-binding motif EF-hand_6 PF13405.6 EGB02182.1 - 5e-05 22.9 0.0 0.087 12.8 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EGB02182.1 - 0.0099 15.4 0.1 0.86 9.3 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EGB02183.1 - 1.5e-13 51.0 0.8 5.1e-11 42.9 0.5 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB02183.1 - 2e-09 36.3 4.7 5.7e-07 28.6 0.5 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB02183.1 - 6.7e-09 35.0 1.8 0.0025 17.6 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EGB02183.1 - 7.7e-08 32.1 5.5 3.1e-06 26.9 2.3 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 EGB02183.1 - 5.1e-07 29.9 0.5 1.8e-06 28.1 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EGB02183.1 - 0.00095 18.6 6.3 0.0013 18.1 0.9 3.7 4 1 1 5 5 5 1 EF hand EF-hand_10 PF14788.6 EGB02183.1 - 0.0099 15.7 0.6 0.018 14.9 0.2 1.7 2 0 0 2 2 2 1 EF hand Lip_prot_lig_C PF10437.9 EGB02183.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus HECT PF00632.25 EGB02184.1 - 2.5e-18 66.6 0.1 2.7e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SNF2_N PF00176.23 EGB02185.1 - 2.9e-07 29.5 0.0 4.9e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGB02185.1 - 0.0066 16.5 0.0 0.0077 16.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGB02185.1 - 0.018 15.3 0.3 0.021 15.1 0.3 1.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGB02185.1 - 0.03 13.9 0.6 0.033 13.7 0.6 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EGB02185.1 - 0.2 11.4 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase S1 PF00575.23 EGB02186.1 - 6.2e-15 55.3 0.1 1e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RF-1 PF00472.20 EGB02186.1 - 1.3e-07 31.5 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 RF-1 domain Peptidase_M23 PF01551.22 EGB02186.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 Semialdhyde_dhC PF02774.18 EGB02186.1 - 0.091 12.8 0.0 5 7.1 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain ABC_trans_N PF14510.6 EGB02187.1 - 0.051 14.2 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal Avl9 PF09794.9 EGB02188.1 - 0.0058 15.4 0.0 0.0079 14.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 YjbE PF11106.8 EGB02188.1 - 0.11 12.8 2.7 0.28 11.4 2.7 1.7 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE ketoacyl-synt PF00109.26 EGB02189.1 - 0.0022 17.6 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DMT_YdcZ PF04657.13 EGB02191.1 - 3e-08 34.0 10.9 3.7e-08 33.8 10.9 1.1 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ VWA PF00092.28 EGB02192.1 - 0.0011 19.2 0.0 0.0016 18.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGB02192.1 - 0.12 13.0 0.0 0.49 11.1 0.0 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Lipase_GDSL_2 PF13472.6 EGB02193.1 - 6.7e-06 26.6 1.0 9.8e-06 26.1 1.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Kinesin PF00225.23 EGB02194.1 - 2.6e-76 256.7 0.0 3e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB02194.1 - 1.5e-10 41.2 0.0 2.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 EGB02194.1 - 0.0028 17.9 0.2 0.033 14.4 0.1 2.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB02194.1 - 0.013 15.9 0.2 0.025 14.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 EGB02194.1 - 0.019 14.8 0.1 0.13 12.0 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase Arm PF00514.23 EGB02195.1 - 8.2e-65 213.0 25.1 1.4e-09 37.7 0.1 7.0 7 0 0 7 7 7 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGB02195.1 - 7.5e-18 64.7 24.3 0.014 15.8 0.2 7.8 3 2 4 7 7 7 7 HEAT-like repeat Arm_2 PF04826.13 EGB02195.1 - 1.5e-13 50.8 1.0 0.00036 20.1 0.0 4.6 1 1 1 4 4 4 3 Armadillo-like HEAT_2 PF13646.6 EGB02195.1 - 1.4e-12 47.8 34.7 9.7e-06 25.9 2.4 4.6 1 1 4 5 5 5 5 HEAT repeats Cnd1 PF12717.7 EGB02195.1 - 2.3e-06 27.7 0.0 0.092 12.8 0.0 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RICTOR_N PF14664.6 EGB02195.1 - 1.7e-05 24.0 0.2 0.003 16.6 0.1 3.1 1 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Phage-A118_gp45 PF10653.9 EGB02195.1 - 3.1e-05 23.9 0.2 5.4 7.1 0.0 5.5 5 1 1 6 6 6 1 Protein gp45 of Bacteriophage A118 Aconitase_B_N PF11791.8 EGB02195.1 - 6.7e-05 23.0 12.0 18 5.4 0.0 6.4 3 3 4 7 7 7 0 Aconitate B N-terminal domain V-ATPase_H_C PF11698.8 EGB02195.1 - 6.7e-05 23.0 0.1 4 7.6 0.0 4.4 2 1 1 4 4 4 1 V-ATPase subunit H GerPB PF10803.8 EGB02195.1 - 7.9e-05 22.7 0.3 43 4.3 0.0 6.0 7 0 0 7 7 7 0 Spore germination GerPB DUF5578 PF17741.1 EGB02195.1 - 8.4e-05 22.1 0.2 0.043 13.2 0.0 3.1 1 1 2 3 3 3 1 Family of unknown function (DUF5578) KAP PF05804.12 EGB02195.1 - 0.00057 18.2 0.0 0.00093 17.5 0.0 1.4 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) ALF PF03752.13 EGB02195.1 - 0.0021 18.0 11.6 1.5 8.9 0.3 5.0 4 0 0 4 4 4 1 Short repeats of unknown function V-ATPase_H_N PF03224.14 EGB02195.1 - 0.0036 16.6 0.0 0.15 11.3 0.0 2.7 1 1 1 2 2 2 1 V-ATPase subunit H Adaptin_N PF01602.20 EGB02195.1 - 0.0086 14.7 0.5 0.088 11.3 0.1 2.6 1 1 2 3 3 3 1 Adaptin N terminal region HEAT PF02985.22 EGB02195.1 - 0.02 15.1 16.2 6.6 7.3 0.1 6.6 6 2 2 8 8 8 0 HEAT repeat SBP_bac_8 PF13416.6 EGB02195.1 - 0.26 11.0 2.0 18 5.0 0.1 3.0 2 1 0 3 3 3 0 Bacterial extracellular solute-binding protein UNC45-central PF11701.8 EGB02195.1 - 0.55 10.2 5.6 0.75 9.8 0.3 3.3 2 2 1 4 4 4 0 Myosin-binding striated muscle assembly central IFRD PF05004.13 EGB02195.1 - 3.1 6.8 11.1 21 4.1 6.3 3.7 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Ion_trans_2 PF07885.16 EGB02196.1 - 4.1e-08 33.1 4.9 6.9e-08 32.3 4.9 1.3 1 0 0 1 1 1 1 Ion channel Trypan_PARP PF05887.11 EGB02196.1 - 0.027 14.5 9.0 0.05 13.6 9.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_5 PF07728.14 EGB02198.1 - 4.1e-09 36.6 0.0 9.9e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EGB02198.1 - 0.032 14.3 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain Clat_adaptor_s PF01217.20 EGB02199.1 - 9.7e-49 165.0 3.5 2.4e-26 92.4 0.8 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Sulfotransfer_4 PF17784.1 EGB02200.1 - 4.1e-18 66.0 0.5 3.2e-09 36.9 0.6 3.2 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB02200.1 - 0.036 14.4 0.3 0.26 11.6 0.0 2.0 1 1 1 2 2 2 0 Sulfotransferase family NAD_binding_10 PF13460.6 EGB02201.1 - 4.3e-11 43.0 0.9 7.6e-11 42.2 0.6 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EGB02201.1 - 0.00024 20.6 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB02201.1 - 0.00037 19.6 0.0 0.00052 19.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thr_dehydrat_C PF00585.18 EGB02202.1 - 1.1e-35 121.2 0.0 2e-19 69.2 0.1 2.0 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF4250 PF14056.6 EGB02202.1 - 0.021 14.8 0.0 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) CPSase_C PF18302.1 EGB02202.1 - 0.26 11.8 0.3 0.26 11.8 0.3 2.1 2 0 0 2 2 2 0 Carbamoyl phosphate synthetase C-terminal domain GST_C_3 PF14497.6 EGB02203.1 - 1.1e-11 44.8 0.0 1.7e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB02203.1 - 0.0001 22.4 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB02203.1 - 0.00096 19.1 1.3 0.0026 17.8 1.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGB02203.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB02203.1 - 0.0091 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Fn3-like PF14310.6 EGB02204.1 - 0.069 13.3 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Fibronectin type III-like domain Phage-tail_3 PF13550.6 EGB02204.1 - 0.092 12.6 1.4 0.13 12.1 0.5 1.9 2 1 0 2 2 2 0 Putative phage tail protein WD40 PF00400.32 EGB02205.1 - 6.2e-43 144.0 36.8 2.2e-08 34.6 1.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB02205.1 - 1.3e-12 47.9 0.6 0.18 12.1 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB02205.1 - 3e-06 26.2 11.1 0.3 9.7 0.5 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 EGB02205.1 - 1.2e-05 25.3 3.0 0.00071 19.5 0.1 3.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGB02205.1 - 0.17 10.8 9.5 19 4.1 0.1 4.3 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Methyltransf_5 PF01795.19 EGB02206.1 - 3.4e-48 164.8 0.0 3.9e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family RRM_1 PF00076.22 EGB02206.1 - 1.1e-07 31.6 0.0 2.4e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.6 EGB02206.1 - 0.0029 17.4 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02206.1 - 0.051 14.3 0.0 0.2 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain VCBS PF13517.6 EGB02208.1 - 1.5e-51 172.8 115.4 9.6e-10 38.9 8.8 7.9 1 1 7 8 8 8 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AbfS_sensor PF18225.1 EGB02208.1 - 5.4e-08 32.6 0.0 4.2 7.4 0.0 6.6 8 0 0 8 8 8 1 Sensor histidine kinase (AbfS) sensor domain Dockerin_1 PF00404.18 EGB02208.1 - 1.8e-07 31.2 45.1 1.3 9.3 7.9 8.1 7 1 1 8 8 8 7 Dockerin type I domain CbiA PF01656.23 EGB02208.1 - 3.6e-05 23.8 12.4 28 4.8 0.0 7.2 5 1 0 5 5 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain HTH_31 PF13560.6 EGB02208.1 - 5.3e-05 23.5 3.0 46 4.5 0.0 6.8 7 0 0 7 7 7 0 Helix-turn-helix domain Hydrolase_4 PF12146.8 EGB02208.1 - 6.8e-05 22.2 6.5 8 5.6 0.0 6.7 6 1 0 7 7 7 1 Serine aminopeptidase, S33 EF-hand_5 PF13202.6 EGB02208.1 - 0.0057 16.1 55.0 1.4 8.6 0.2 8.6 8 0 0 8 8 8 7 EF hand LcrR PF09621.10 EGB02208.1 - 0.059 12.8 1.5 26 4.3 0.0 5.1 6 2 1 8 8 8 0 Type III secretion system regulator (LcrR) vWF_A PF12450.8 EGB02208.1 - 0.35 10.8 11.1 6.2 6.8 0.0 6.3 8 0 0 8 8 8 0 von Willebrand factor PH_8 PF15409.6 EGB02208.1 - 0.87 9.9 5.1 11 6.4 0.1 4.1 4 1 1 5 5 5 0 Pleckstrin homology domain DUF3927 PF13064.6 EGB02208.1 - 3.9 7.5 10.7 7.6 6.6 0.2 5.4 6 0 0 6 6 6 0 Protein of unknown function (DUF3927) RRM_1 PF00076.22 EGB02209.1 - 7e-11 41.8 1.1 1.7e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EGB02210.1 - 4.3e-61 206.6 0.0 5.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02210.1 - 2.7e-28 99.0 0.0 3.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB02210.1 - 4.5e-05 22.6 0.7 7e-05 21.9 0.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB02210.1 - 0.00098 18.5 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB02210.1 - 0.071 11.9 0.0 0.45 9.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EGB02210.1 - 0.098 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3275 PF11679.8 EGB02210.1 - 1.8 8.5 5.3 3.8 7.4 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) 5_nucleotid_C PF02872.18 EGB02211.1 - 2.7e-10 40.7 0.0 4.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain SART-1 PF03343.13 EGB02212.1 - 7.5e-25 87.6 18.6 1.4e-18 66.8 2.9 2.8 2 1 1 3 3 3 2 SART-1 family DEAD PF00270.29 EGB02213.1 - 2.3e-34 118.7 0.0 2.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB02213.1 - 0.0044 17.0 0.0 0.0054 16.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGB02213.1 - 0.16 12.3 0.1 1.3 9.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF2465 PF10239.9 EGB02214.1 - 0.0027 17.0 3.6 0.01 15.1 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2465) ULD PF16534.5 EGB02215.1 - 0.031 14.3 0.2 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-like oligomerisation domain of SATB TT_ORF2a PF08197.11 EGB02215.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 pORF2a truncated protein BLOC1_2 PF10046.9 EGB02215.1 - 0.26 11.6 14.7 1.2 9.5 0.1 4.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 EGB02215.1 - 2.7 7.8 23.2 0.91 9.3 5.0 4.0 1 1 1 3 3 3 0 Phage minor structural protein GP20 DUF5344 PF17279.2 EGB02215.1 - 3.6 8.2 9.4 0.34 11.5 0.5 3.3 2 1 2 4 4 4 0 Family of unknown function (DUF5344) ParE_toxin PF05016.15 EGB02215.1 - 7 7.3 9.2 18 6.0 0.3 3.7 3 2 1 4 4 4 0 ParE toxin of type II toxin-antitoxin system, parDE LRR_8 PF13855.6 EGB02216.1 - 2.7e-13 49.5 0.8 9.1e-07 28.6 0.1 3.7 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGB02216.1 - 8.4e-11 41.9 0.0 0.00022 21.6 0.0 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB02216.1 - 0.0001 22.1 0.1 39 4.7 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 EGB02216.1 - 0.0054 17.1 0.7 29 5.7 0.0 4.9 5 2 0 5 5 5 1 Leucine Rich Repeat RVT_2 PF07727.14 EGB02217.1 - 1.4e-06 28.1 0.0 1.5e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_4 PF13637.6 EGB02218.1 - 1.4e-11 44.6 0.1 2.6e-10 40.6 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB02218.1 - 1.5e-09 38.3 0.4 0.00034 21.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB02218.1 - 1.5e-08 34.7 3.1 0.00031 21.0 0.1 3.2 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB02218.1 - 1.6e-07 31.1 0.3 0.0079 16.6 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGB02218.1 - 0.00089 19.6 1.6 4 8.0 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat ELFV_dehydrog_N PF02812.18 EGB02220.1 - 1.4e-33 115.5 0.0 1.8e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Complex1_LYR PF05347.15 EGB02221.1 - 0.0008 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) p450 PF00067.22 EGB02222.1 - 2.5e-14 52.9 0.0 2.7e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 G-patch_2 PF12656.7 EGB02223.1 - 0.13 12.4 0.2 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 G-patch domain DUF2656 PF10847.8 EGB02223.1 - 0.19 11.8 0.1 0.31 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) JmjC PF02373.22 EGB02224.1 - 0.00015 22.2 0.0 0.00036 20.9 0.0 1.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGB02224.1 - 0.056 13.1 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain Ion_trans PF00520.31 EGB02225.1 - 7.3e-09 35.2 1.5 1.2e-08 34.5 1.5 1.3 1 0 0 1 1 1 1 Ion transport protein Mannosyl_trans3 PF11051.8 EGB02225.1 - 1.5e-07 31.1 0.0 4.7e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative Acyl_transf_3 PF01757.22 EGB02226.1 - 5.7e-29 101.2 0.0 3.3e-28 98.7 0.0 1.9 1 1 1 2 2 2 1 Acyltransferase family Innate_immun PF12782.7 EGB02226.1 - 0.19 11.2 0.9 0.36 10.3 0.9 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DEAD PF00270.29 EGB02228.1 - 8.3e-33 113.6 0.0 9.3e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB02228.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGB02228.1 - 0.044 14.1 0.2 0.39 11.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain RrnaAD PF00398.20 EGB02231.1 - 1e-46 159.2 0.0 1.2e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGB02231.1 - 2.5e-09 37.7 0.0 4.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB02231.1 - 1.3e-06 29.0 0.0 2.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB02231.1 - 8.8e-06 25.6 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGB02231.1 - 4.3e-05 24.2 0.0 9.4e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGB02231.1 - 5.6e-05 22.5 0.0 8.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EGB02231.1 - 0.00012 21.9 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB02231.1 - 0.00025 20.7 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EGB02231.1 - 0.00086 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_31 PF13847.6 EGB02231.1 - 0.0011 18.8 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EGB02231.1 - 0.0013 18.4 0.0 0.0057 16.4 0.0 1.8 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 EGB02231.1 - 0.0029 17.0 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGB02231.1 - 0.005 16.3 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EGB02231.1 - 0.031 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGB02231.1 - 0.054 12.9 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGB02231.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain BLUF PF04940.12 EGB02231.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Sensors of blue-light using FAD PhzC-PhzF PF02567.16 EGB02232.1 - 6.4e-31 107.9 0.1 7.2e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 EGB02232.1 - 0.0036 16.4 0.0 0.0046 16.0 0.0 1.1 1 0 0 1 1 1 1 Proline racemase zf-RING_2 PF13639.6 EGB02233.1 - 2e-12 47.2 5.0 3.4e-12 46.5 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGB02233.1 - 7.8e-10 38.9 4.0 1.7e-09 37.8 4.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGB02233.1 - 1.7e-09 37.5 1.9 6.2e-09 35.7 0.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGB02233.1 - 5e-09 35.9 6.8 8e-09 35.2 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB02233.1 - 2e-08 34.0 4.1 3.2e-08 33.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGB02233.1 - 4.7e-07 29.4 1.0 8.6e-07 28.6 1.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EGB02233.1 - 1.4e-06 28.3 2.8 2.4e-06 27.5 2.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGB02233.1 - 1.4e-06 28.1 1.9 2.3e-06 27.4 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB02233.1 - 4.3e-06 26.6 2.7 7.4e-06 25.8 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGB02233.1 - 0.00021 21.1 1.0 0.00021 21.1 1.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGB02233.1 - 0.00069 19.2 3.0 0.0011 18.5 3.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EGB02233.1 - 0.00078 19.5 3.7 0.0015 18.6 3.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Sbi-IV PF11621.8 EGB02233.1 - 0.00079 19.7 0.5 1.9 8.9 0.0 2.6 3 0 0 3 3 2 2 C3 binding domain 4 of IgG-bind protein SBI zf-Nse PF11789.8 EGB02233.1 - 0.03 14.2 3.0 0.052 13.4 3.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TerY_C PF15616.6 EGB02233.1 - 0.034 14.3 2.4 0.059 13.5 2.4 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zinc_ribbon_16 PF17034.5 EGB02233.1 - 0.053 13.7 0.6 0.1 12.8 0.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family Phage-MuB_C PF09077.11 EGB02233.1 - 0.14 12.0 2.0 21 5.1 0.0 3.3 3 0 0 3 3 3 0 Mu B transposition protein, C terminal zinc-ribbons_6 PF07191.12 EGB02233.1 - 0.22 11.5 2.3 0.41 10.6 2.3 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 EGB02233.1 - 0.22 11.3 3.2 0.53 10.1 3.1 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EGB02233.1 - 1.9 8.7 6.4 21 5.4 6.4 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EGB02233.1 - 2.1 8.4 9.7 0.082 13.0 1.3 2.3 2 0 0 2 2 2 0 Zinc-finger Prok-RING_1 PF14446.6 EGB02233.1 - 2.6 8.0 5.3 4 7.5 1.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PDZ PF00595.24 EGB02234.1 - 0.00014 22.2 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Methyltransf_16 PF10294.9 EGB02235.1 - 7.8e-11 42.0 0.0 9.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGB02235.1 - 5.1e-06 26.1 0.0 6.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB02235.1 - 5.2e-06 27.1 0.1 7.9e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGB02235.1 - 0.00042 19.8 0.0 0.00051 19.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EGB02235.1 - 0.0035 17.1 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGB02235.1 - 0.0038 18.0 0.1 0.0064 17.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02235.1 - 0.0077 16.0 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB02235.1 - 0.017 14.4 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGB02235.1 - 0.099 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Mem_trans PF03547.18 EGB02236.1 - 0.00077 18.0 0.2 0.00078 17.9 0.2 1.1 1 0 0 1 1 1 1 Membrane transport protein VEGFR-2_TMD PF17988.1 EGB02236.1 - 0.092 12.2 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain PhyH PF05721.13 EGB02237.1 - 4.7e-08 33.6 0.3 3.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DnaJ PF00226.31 EGB02238.1 - 0.0024 18.0 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain PT-VENN PF04829.13 EGB02238.1 - 0.48 10.5 11.0 0.63 10.2 0.3 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Gly-zipper_Omp PF13488.6 EGB02238.1 - 0.51 10.4 20.3 2 8.5 5.7 2.4 2 0 0 2 2 2 0 Glycine zipper Glug PF07581.12 EGB02238.1 - 1.3 9.5 13.0 6.6 7.4 1.9 2.7 2 0 0 2 2 2 0 The GLUG motif Rick_17kDa_Anti PF05433.15 EGB02238.1 - 3.9 7.4 23.9 5.1 7.0 7.6 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Helo_like_N PF17111.5 EGB02239.1 - 0.081 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins UVR PF02151.19 EGB02241.1 - 1.9e-05 24.3 7.7 0.0097 15.6 3.4 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif DUF2007 PF09413.10 EGB02241.1 - 0.13 12.4 1.2 0.72 10.1 0.1 2.3 1 1 1 2 2 2 0 Putative prokaryotic signal transducing protein TPR_11 PF13414.6 EGB02242.1 - 2.4e-22 78.4 3.9 2.3e-05 24.0 0.1 4.6 1 1 4 5 5 5 4 TPR repeat TPR_1 PF00515.28 EGB02242.1 - 2.8e-18 64.9 0.9 6.7e-05 22.5 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02242.1 - 1.1e-16 59.5 10.4 0.0014 18.6 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02242.1 - 8.5e-15 55.1 42.8 2.2e-07 31.4 10.6 4.8 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02242.1 - 2.1e-13 49.9 27.4 1e-05 25.9 0.9 5.9 2 1 5 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGB02242.1 - 1.1e-11 44.3 0.7 0.081 13.3 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB02242.1 - 4.9e-10 39.5 17.7 0.00034 20.8 1.2 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGB02242.1 - 1.5e-09 37.9 18.4 1.5e-05 25.0 1.9 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02242.1 - 3.2e-09 36.3 0.0 0.14 12.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB02242.1 - 2.1e-08 34.5 17.9 0.00046 20.6 0.6 4.1 2 1 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02242.1 - 8e-07 28.7 7.9 2.4 8.4 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02242.1 - 2.8e-06 27.6 5.5 0.099 13.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Methyltransf_25 PF13649.6 EGB02242.1 - 6e-05 23.7 0.0 0.00019 22.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain BTAD PF03704.17 EGB02242.1 - 6.1e-05 23.5 1.0 6.1e-05 23.5 1.0 2.8 1 1 3 4 4 4 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 EGB02242.1 - 0.00015 21.5 21.2 3 7.8 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB02242.1 - 0.0002 21.5 0.2 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGB02242.1 - 0.00025 20.4 2.6 0.0008 18.7 1.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat Methyltransf_12 PF08242.12 EGB02242.1 - 0.0023 18.6 0.0 0.0074 17.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02242.1 - 0.0063 16.3 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPR_20 PF14561.6 EGB02242.1 - 0.009 16.3 9.2 3.7 7.9 0.1 4.0 1 1 4 5 5 5 3 Tetratricopeptide repeat Methyltransf_11 PF08241.12 EGB02242.1 - 0.009 16.6 0.0 0.021 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPR_4 PF07721.14 EGB02242.1 - 0.014 16.0 33.4 2.3 9.1 0.0 6.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EGB02242.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGB02242.1 - 0.024 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGB02242.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SAC3_GANP PF03399.16 EGB02243.1 - 1.5e-12 47.5 0.0 1.6e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGB02243.1 - 5.5e-10 39.4 0.0 6.2e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family AAA_5 PF07728.14 EGB02244.1 - 1.1e-23 83.7 0.0 1.4e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB02244.1 - 3.1e-05 23.8 0.0 5.7e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGB02244.1 - 0.00037 20.5 0.0 0.0038 17.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGB02244.1 - 0.0036 16.7 0.0 0.54 9.6 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGB02244.1 - 0.0037 17.6 1.4 0.24 11.8 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 EGB02244.1 - 0.0038 17.7 0.0 0.0046 17.4 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGB02244.1 - 0.0046 17.1 0.0 0.0068 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB02244.1 - 0.0075 16.8 0.0 0.011 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EGB02244.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGB02244.1 - 0.011 16.0 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGB02244.1 - 0.053 13.3 0.0 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Dynein_heavy PF03028.15 EGB02244.1 - 0.071 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 EGB02244.1 - 0.17 10.8 0.0 0.37 9.7 0.0 1.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_2 PF07724.14 EGB02244.1 - 0.17 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGB02244.1 - 0.24 11.6 0.3 1.9 8.8 0.3 2.1 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EGB02245.1 - 0.0017 17.4 0.2 0.0024 16.9 0.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DivIC PF04977.15 EGB02245.1 - 0.049 13.4 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Cytomega_UL20A PF05984.12 EGB02246.1 - 1.6 9.1 4.3 0.84 10.0 2.3 1.5 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein PsbQ PF05757.11 EGB02247.1 - 0.037 13.8 5.5 0.21 11.3 0.5 2.9 3 0 0 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) PI-PLC-X PF00388.19 EGB02248.1 - 2.1e-28 98.8 0.1 2.3e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Nop14 PF04147.12 EGB02251.1 - 0.16 10.1 10.1 0.25 9.5 10.1 1.3 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 EGB02251.1 - 1.1 8.5 12.0 0.04 13.3 5.2 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RRN3 PF05327.11 EGB02251.1 - 2.5 6.5 5.0 3.8 5.9 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 EGB02252.1 - 1.8e-70 237.4 0.2 2.6e-70 236.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02252.1 - 1.8e-34 119.2 0.1 2.8e-34 118.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB02252.1 - 0.00069 19.0 0.1 0.0017 17.7 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC4_D PF16856.5 EGB02252.1 - 0.017 15.0 0.1 0.056 13.3 0.1 1.9 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain APH PF01636.23 EGB02252.1 - 0.047 13.6 0.1 0.46 10.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family EMP70 PF02990.16 EGB02253.1 - 2.9e-113 379.3 17.6 3.6e-113 379.0 17.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 COPIIcoated_ERV PF07970.12 EGB02255.1 - 6.7e-15 55.5 0.0 7.9e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter PhoLip_ATPase_N PF16209.5 EGB02256.1 - 1.7e-15 56.5 0.6 2.4e-15 56.0 0.6 1.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal RimM PF01782.18 EGB02257.1 - 0.004 17.3 0.0 4.6 7.5 0.0 2.3 2 0 0 2 2 2 2 RimM N-terminal domain IR1-M PF12185.8 EGB02257.1 - 0.055 13.4 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DUF732 PF05305.14 EGB02257.1 - 0.06 13.7 1.2 12 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Acetyltransf_6 PF13480.7 EGB02257.1 - 0.22 11.7 1.9 13 6.0 0.1 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy_3 PF13640.6 EGB02258.1 - 5.9e-16 59.1 0.0 1.1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB02258.1 - 1.2e-05 25.9 0.0 0.00025 21.7 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EGB02258.1 - 0.0007 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase PhyH PF05721.13 EGB02258.1 - 0.0084 16.4 0.2 0.025 14.8 0.2 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cu-oxidase_3 PF07732.15 EGB02260.1 - 2e-13 50.4 0.1 2e-11 43.9 0.3 2.6 2 1 0 2 2 2 1 Multicopper oxidase Beta-lactamase PF00144.24 EGB02261.1 - 1.2e-18 67.5 0.6 1.6e-18 67.1 0.6 1.1 1 0 0 1 1 1 1 Beta-lactamase MtN3_slv PF03083.16 EGB02261.1 - 0.00013 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange LRR_4 PF12799.7 EGB02262.1 - 1.7e-29 101.4 8.6 1.1e-05 25.7 0.0 6.8 6 1 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB02262.1 - 4.4e-29 100.0 11.7 3.5e-10 39.5 1.2 5.9 4 3 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 EGB02262.1 - 4.1e-09 35.7 17.1 2.5 9.0 0.1 9.8 11 1 0 11 11 11 3 Leucine Rich Repeat LRR_9 PF14580.6 EGB02262.1 - 1.2e-05 24.9 1.4 0.0077 15.8 0.1 3.4 3 1 1 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 EGB02262.1 - 8.8e-05 22.3 22.9 0.28 11.3 0.1 7.9 9 0 0 9 9 9 3 Leucine Rich repeat CREPT PF16566.5 EGB02262.1 - 0.022 15.0 0.4 23 5.1 0.0 4.2 2 1 2 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour LRR_5 PF13306.6 EGB02262.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DUF3127 PF11325.8 EGB02263.1 - 1.8e-20 72.9 0.0 2.3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3127) zf-CCCH_2 PF14608.6 EGB02264.1 - 0.0047 17.4 4.0 0.01 16.3 4.0 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCHH PF10283.9 EGB02264.1 - 2.5 8.2 10.5 4.1 7.5 10.5 1.3 1 0 0 1 1 1 0 PBZ domain ETF_QO PF05187.13 EGB02266.1 - 2.4e-32 111.1 0.0 2.8e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_7 PF12838.7 EGB02266.1 - 0.0046 17.5 2.1 0.0072 16.9 2.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Ras PF00071.22 EGB02268.1 - 1.7e-60 203.3 0.1 2.2e-60 203.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB02268.1 - 6.3e-33 113.5 0.1 1.2e-32 112.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB02268.1 - 3.5e-13 49.4 0.0 4.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB02268.1 - 7.1e-06 26.1 0.0 1.7e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB02268.1 - 9.5e-05 22.4 0.0 0.12 12.2 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGB02268.1 - 0.00014 21.3 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGB02268.1 - 0.0014 18.2 0.1 0.0084 15.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGB02268.1 - 0.014 15.7 0.1 0.046 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 EGB02268.1 - 0.068 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MutL_C PF08676.11 EGB02269.1 - 2.4e-13 50.1 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 MutL C terminal dimerisation domain PseudoU_synth_2 PF00849.22 EGB02271.1 - 7.4e-16 58.6 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF1336 PF07059.12 EGB02271.1 - 1.1e-06 28.9 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) ABC_membrane PF00664.23 EGB02272.1 - 1.3e-14 54.5 0.1 1.4e-14 54.4 0.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DnaJ PF00226.31 EGB02273.1 - 2.6e-21 75.5 0.2 4.4e-21 74.8 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EGB02273.1 - 5.3e-20 72.0 0.0 8.4e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGB02273.1 - 1e-13 51.4 14.6 2e-13 50.5 14.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGB02273.1 - 0.014 15.3 16.9 0.45 10.5 4.2 3.2 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 EGB02273.1 - 0.54 10.3 10.1 1.1 9.3 9.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 EGB02273.1 - 0.58 9.8 7.3 0.51 10.0 1.6 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 EGB02273.1 - 0.66 10.0 7.3 2.1 8.4 7.3 1.8 1 1 0 1 1 1 0 zinc-ribbons zf-CHY PF05495.12 EGB02273.1 - 4.5 7.8 7.2 1.1 9.7 2.5 2.0 1 1 1 2 2 2 0 CHY zinc finger RseC_MucC PF04246.12 EGB02273.1 - 6.4 6.7 10.0 0.94 9.4 2.1 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ERGIC_N PF13850.6 EGB02274.1 - 1.6e-23 82.8 0.0 3.1e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 EGB02274.1 - 2.7e-20 72.3 0.0 4.5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin COPIIcoated_ERV PF07970.12 EGB02274.1 - 8.9e-08 32.2 0.1 2.1e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin_2 PF13098.6 EGB02274.1 - 2.6e-06 27.8 0.0 5.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGB02274.1 - 5.8e-05 22.6 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGB02274.1 - 0.0042 17.2 0.2 0.023 14.9 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EGB02274.1 - 0.025 14.5 0.1 0.081 12.8 0.1 1.8 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EGB02274.1 - 0.058 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Hint PF01079.20 EGB02277.1 - 2.8e-10 40.1 0.0 5.8e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 Hint module Peptidase_S8 PF00082.22 EGB02278.1 - 2.1e-23 83.1 5.5 2.4e-23 82.8 5.5 1.0 1 0 0 1 1 1 1 Subtilase family Sulfotransfer_2 PF03567.14 EGB02279.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase family Ank_2 PF12796.7 EGB02280.1 - 3.2e-16 59.7 0.1 9.7e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB02280.1 - 9.2e-08 32.5 1.9 0.00044 20.7 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB02280.1 - 1.4e-07 31.6 0.1 2.4e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB02280.1 - 2.7e-07 30.7 1.4 1.4e-05 25.3 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EGB02280.1 - 1.5e-06 28.1 1.1 0.0018 18.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat DUF883 PF05957.13 EGB02284.1 - 0.094 13.3 1.3 0.33 11.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGB02284.1 - 0.19 12.3 0.9 0.79 10.3 0.9 2.1 1 1 0 1 1 1 0 YtxH-like protein adh_short PF00106.25 EGB02286.1 - 3.8e-33 114.6 1.8 4.4e-33 114.4 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB02286.1 - 3.2e-26 92.3 2.5 3.7e-26 92.1 2.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB02286.1 - 7.6e-11 42.2 3.2 1e-10 41.8 3.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB02286.1 - 0.027 13.9 1.3 0.043 13.3 1.3 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 EGB02288.1 - 6.2e-12 46.0 0.0 9.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02288.1 - 3.3e-10 39.9 0.0 4.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02288.1 - 3.4e-10 40.5 0.0 6.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB02288.1 - 3.1e-06 26.7 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGB02288.1 - 0.00016 22.4 0.0 0.00024 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EGB02288.1 - 0.0034 16.0 0.0 0.0046 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 EGB02288.1 - 0.0039 16.7 0.0 0.0071 15.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EGB02288.1 - 0.026 14.4 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase PI3_PI4_kinase PF00454.27 EGB02289.1 - 2.8e-33 115.8 0.0 6.3e-32 111.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EGB02289.1 - 0.0025 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) NADH5_C PF06455.11 EGB02289.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus PQQ_2 PF13360.6 EGB02292.1 - 0.19 11.3 2.1 2.1 7.9 2.1 2.3 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.6 EGB02292.1 - 0.68 10.5 13.8 1.4 9.5 0.1 5.4 4 2 0 4 4 4 0 PQQ-like domain SPESP1 PF15754.5 EGB02293.1 - 0.013 14.7 0.5 0.041 13.0 0.5 1.7 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 GRP PF07172.11 EGB02295.1 - 1.3 9.8 16.2 2.1 9.1 16.2 1.4 1 0 0 1 1 1 0 Glycine rich protein family Pinin_SDK_N PF04697.13 EGB02295.1 - 2.6 8.7 8.2 1.9 9.2 6.5 1.6 2 0 0 2 2 2 0 pinin/SDK conserved region CDPS PF16715.5 EGB02296.1 - 0.022 14.4 0.1 0.047 13.3 0.0 1.5 2 0 0 2 2 2 0 Cyclodipeptide synthase zf-ACC PF17848.1 EGB02296.1 - 0.069 13.2 3.8 25 5.0 0.1 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Daxx PF03344.15 EGB02296.1 - 0.072 13.2 0.0 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain Pkinase PF00069.25 EGB02297.1 - 1.1e-49 169.3 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02297.1 - 1.6e-20 73.5 0.0 1.9e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB02297.1 - 3e-06 26.8 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB02297.1 - 5.8e-05 22.0 0.0 8.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB02297.1 - 8.2e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB02297.1 - 0.0073 16.3 0.2 0.016 15.2 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family ACCA PF03255.14 EGB02300.1 - 0.00037 20.4 0.3 4.5 7.1 0.0 3.8 2 2 2 4 4 4 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fip1 PF05182.13 EGB02300.1 - 0.039 13.5 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Fip1 motif Hum_adeno_E3A PF05393.11 EGB02300.1 - 0.065 13.2 0.0 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein C1_1 PF00130.22 EGB02301.1 - 0.2 11.6 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_12 PF13424.6 EGB02302.1 - 2.6e-58 194.3 31.0 9.8e-18 64.2 1.5 4.3 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02302.1 - 1.3e-51 171.1 24.9 4.9e-12 45.3 0.8 6.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02302.1 - 2.4e-23 80.9 15.3 6.7e-05 22.5 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02302.1 - 4.7e-23 79.4 20.8 0.00037 20.4 0.5 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02302.1 - 1.1e-19 69.0 19.0 6.1e-05 22.8 0.1 6.4 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02302.1 - 1.7e-15 55.9 13.1 0.00043 20.3 0.3 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02302.1 - 5e-15 55.9 21.1 1.1e-06 29.2 4.4 5.7 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGB02302.1 - 1.4e-09 37.7 12.9 0.096 13.1 0.2 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB02302.1 - 2.1e-09 37.8 13.4 0.013 16.0 1.0 4.9 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB02302.1 - 1.9e-08 34.1 7.7 0.0014 18.1 0.1 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 EGB02302.1 - 6e-08 32.9 22.6 0.42 11.6 0.5 6.5 2 1 4 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB02302.1 - 5.5e-06 26.5 7.0 0.5 10.6 1.5 5.2 1 1 5 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 EGB02302.1 - 2.8e-05 23.7 0.7 2.8e-05 23.7 0.7 1.7 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 EGB02302.1 - 6.7e-05 23.1 7.0 4.3 8.2 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB02302.1 - 9.2e-05 22.0 13.3 0.46 10.2 0.3 6.1 6 1 1 7 7 7 2 TPR repeat DUF4404 PF14357.6 EGB02302.1 - 0.00026 21.6 1.3 6.3 7.5 0.1 4.1 3 2 2 5 5 5 1 Domain of unknown function (DUF4404) SHNi-TPR PF10516.9 EGB02302.1 - 0.00027 20.3 0.1 0.29 10.6 0.0 3.9 5 0 0 5 5 5 1 SHNi-TPR TAtT PF16811.5 EGB02302.1 - 0.016 14.5 3.1 0.67 9.2 0.1 2.7 1 1 2 3 3 3 0 TRAP transporter T-component TPR_9 PF13371.6 EGB02302.1 - 0.016 15.3 7.9 0.16 12.2 1.7 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGB02302.1 - 0.052 13.6 8.6 14 5.8 0.0 4.7 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGB02302.1 - 0.069 13.8 19.5 9.8 7.1 0.6 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat PI3K_P85_iSH2 PF16454.5 EGB02302.1 - 0.086 12.4 0.1 0.55 9.8 0.0 2.2 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_5 PF12688.7 EGB02302.1 - 0.1 12.9 7.2 12 6.2 2.9 4.6 3 2 0 3 3 3 0 Tetratrico peptide repeat Coatomer_E PF04733.14 EGB02302.1 - 0.1 12.0 0.6 3.7 6.9 0.0 2.8 2 1 1 3 3 3 0 Coatomer epsilon subunit CMV_1a_C PF12503.8 EGB02302.1 - 0.2 11.7 0.0 16 5.6 0.0 2.3 1 1 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal TPR_3 PF07720.12 EGB02302.1 - 0.34 11.0 9.7 1.7 8.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 EGB02303.1 - 6.6e-14 52.6 0.0 1e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB02303.1 - 0.077 13.5 0.0 0.31 11.5 0.0 1.9 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily Ferrochelatase PF00762.19 EGB02304.1 - 4.6e-51 173.8 0.0 5.3e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Beta-lactamase PF00144.24 EGB02305.1 - 1.7e-13 50.5 13.1 9.2e-12 44.8 1.9 2.1 1 1 1 2 2 2 2 Beta-lactamase Sulfatase PF00884.23 EGB02306.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Sulfatase Ku PF02735.16 EGB02307.1 - 3.7e-15 56.2 0.0 6.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain SAP PF02037.27 EGB02307.1 - 9.2e-05 22.1 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ku_N PF03731.15 EGB02307.1 - 0.11 12.2 0.0 1.1 8.9 0.0 2.0 1 1 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain EF-hand_1 PF00036.32 EGB02309.1 - 1.2e-16 58.9 1.7 7.9e-09 34.5 1.4 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB02309.1 - 2.9e-14 53.3 0.2 3.1e-14 53.2 0.2 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB02309.1 - 7.6e-14 50.4 1.0 9.6e-06 25.1 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB02309.1 - 6.1e-11 41.3 1.7 1.2e-05 24.6 1.8 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB02309.1 - 7.7e-10 38.5 0.9 2.6e-09 36.8 0.4 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 EGB02309.1 - 1.3e-06 28.3 0.5 7.6e-06 25.8 0.2 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGB02309.1 - 0.0016 18.7 0.1 0.0021 18.4 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB02309.1 - 0.025 14.9 0.0 0.03 14.7 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PITH PF06201.13 EGB02310.1 - 2.4e-23 83.0 0.0 3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain EF-hand_6 PF13405.6 EGB02311.1 - 2.3e-08 33.3 7.7 0.0011 18.7 0.3 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGB02311.1 - 4.5e-08 32.1 5.8 0.00012 21.4 0.3 3.6 3 1 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EGB02311.1 - 8.4e-06 25.1 1.7 0.043 13.3 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB02311.1 - 0.001 19.5 6.3 0.0042 17.5 1.9 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB02311.1 - 0.015 15.2 0.5 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_14 PF17959.1 EGB02311.1 - 0.15 12.4 0.2 13 6.2 0.2 2.2 1 1 1 2 2 2 0 EF-hand domain Endothelin PF00322.17 EGB02312.1 - 0.17 11.5 4.2 10 5.8 0.3 3.0 2 0 0 2 2 2 0 Endothelin family GAF PF01590.26 EGB02314.1 - 7.7e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain OmpA PF00691.20 EGB02315.1 - 8.2e-19 67.8 0.0 2.7e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 OmpA family Tyrosinase PF00264.20 EGB02315.1 - 3.1e-07 30.9 0.0 3.4e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Common central domain of tyrosinase Ribosomal_S11 PF00411.19 EGB02316.1 - 7.2e-47 158.3 1.3 9.5e-47 158.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 EGB02316.1 - 0.026 13.6 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Ribosomal_L18p PF00861.22 EGB02316.1 - 0.049 14.0 0.1 0.076 13.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Pilus_CpaD PF09476.10 EGB02316.1 - 0.056 13.2 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) CBM_25 PF03423.13 EGB02316.1 - 0.058 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) FA_hydroxylase PF04116.13 EGB02317.1 - 7e-14 52.3 12.9 1.6e-13 51.2 12.9 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Shikimate_dh_N PF08501.11 EGB02319.1 - 1e-10 41.7 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EGB02319.1 - 4.9e-10 39.0 1.2 9.1e-10 38.1 1.2 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EGB02319.1 - 0.017 15.2 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FA_desaturase PF00487.24 EGB02321.1 - 8e-28 97.9 17.7 1.1e-27 97.5 17.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Aldo_ket_red PF00248.21 EGB02323.1 - 4.4e-42 144.3 0.0 5.5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family 7TMR-DISM_7TM PF07695.11 EGB02325.1 - 0.0015 18.5 3.9 0.0022 18.0 3.9 1.3 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF3112 PF11309.8 EGB02325.1 - 0.77 9.2 5.7 1.8 8.0 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) FHA PF00498.26 EGB02327.1 - 0.0018 18.6 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGB02327.1 - 0.11 12.8 0.0 0.44 10.9 0.0 2.0 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Pup PF05639.11 EGB02327.1 - 0.13 13.2 0.2 0.13 13.2 0.2 2.1 2 0 0 2 2 2 0 Pup-like protein Dicty_REP PF05086.12 EGB02327.1 - 0.13 10.3 6.0 0.17 9.8 6.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_lambd_f PF10391.9 EGB02327.1 - 0.83 9.5 2.5 8.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda DUF4407 PF14362.6 EGB02327.1 - 1.2 8.4 6.8 1.8 7.8 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mur_ligase_M PF08245.12 EGB02328.1 - 0.015 15.3 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Mur ligase middle domain ABC_tran PF00005.27 EGB02329.1 - 1.5e-07 32.0 0.3 7.6e-07 29.7 0.0 2.1 2 1 0 2 2 2 1 ABC transporter RasGAP_C PF03836.15 EGB02329.1 - 2.4 8.3 11.2 2.7 8.1 9.8 1.8 2 0 0 2 2 2 0 RasGAP C-terminus AAA_23 PF13476.6 EGB02329.1 - 2.8 8.4 11.5 4.8 7.6 11.5 1.4 1 0 0 1 1 1 0 AAA domain ISG65-75 PF11727.8 EGB02329.1 - 3.3 6.9 18.6 4.8 6.3 18.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein P5CR_dimer PF14748.6 EGB02330.1 - 5.6e-36 122.9 0.2 1.2e-35 121.9 0.1 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGB02330.1 - 5.2e-10 39.8 0.0 2e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGB02330.1 - 0.00066 19.9 0.0 0.0022 18.2 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGB02330.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Trypan_glycop_C PF10659.9 EGB02331.1 - 4.9e-06 26.9 77.4 0.025 14.9 11.4 4.4 1 1 3 4 4 4 4 Trypanosome variant surface glycoprotein C-terminal domain LRR_4 PF12799.7 EGB02331.1 - 0.0026 18.1 0.0 0.26 11.8 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Paramecium_SA PF01508.16 EGB02331.1 - 0.073 13.5 59.0 1.6 9.2 8.4 4.3 2 1 2 4 4 4 0 Paramecium surface antigen domain HEAT PF02985.22 EGB02332.1 - 0.0045 17.1 9.2 0.0095 16.1 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EGB02332.1 - 0.051 14.1 2.2 0.051 14.1 2.2 3.4 4 1 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 EGB02332.1 - 1.2 9.6 7.2 1.9 8.9 1.8 3.3 3 1 1 4 4 4 0 HEAT repeats NTP_transf_2 PF01909.23 EGB02334.1 - 1.8e-09 37.7 0.0 3.8e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGB02334.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Myosin_head PF00063.21 EGB02335.1 - 0.27 9.4 0.0 0.31 9.2 0.0 1.0 1 0 0 1 1 1 0 Myosin head (motor domain) Ank_2 PF12796.7 EGB02336.1 - 2.3e-16 60.1 1.0 5.3e-10 39.8 0.3 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB02336.1 - 2.8e-12 46.6 7.3 2.4e-07 30.9 0.3 4.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB02336.1 - 3.3e-07 30.1 3.7 0.023 15.2 0.1 4.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EGB02336.1 - 1.1e-06 29.1 1.7 0.0015 19.1 0.5 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB02336.1 - 2.7e-05 24.4 9.4 0.027 14.9 0.4 4.2 3 0 0 3 3 3 2 Ankyrin repeat Dynamin_N PF00350.23 EGB02336.1 - 7.9e-05 22.8 0.0 0.00023 21.2 0.0 1.6 1 1 1 2 2 2 1 Dynamin family Peptidase_M13_N PF05649.13 EGB02337.1 - 5.7e-15 55.9 0.0 1.2e-14 54.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M13 Fibrillarin PF01269.17 EGB02337.1 - 4.9e-14 52.0 0.0 8.5e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin zf-MYND PF01753.18 EGB02337.1 - 3e-08 33.6 11.6 3e-08 33.6 11.6 3.3 3 1 0 3 3 3 1 MYND finger DnaJ PF00226.31 EGB02339.1 - 1.9e-21 75.9 0.1 2.2e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGB02339.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 A repeated domain in UCH-protein Hexapep PF00132.24 EGB02340.1 - 0.0012 18.5 4.7 0.0021 17.7 4.7 1.5 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) DnaJ PF00226.31 EGB02341.1 - 1.8e-17 63.2 0.3 2e-17 63.1 0.3 1.0 1 0 0 1 1 1 1 DnaJ domain SBDS_C PF09377.10 EGB02341.1 - 0.0041 17.1 0.1 0.0046 17.0 0.1 1.0 1 0 0 1 1 1 1 SBDS protein C-terminal domain RsbRD_N PF14361.6 EGB02341.1 - 0.077 13.7 0.0 0.083 13.6 0.0 1.0 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Ank_2 PF12796.7 EGB02342.1 - 1.2e-32 112.3 0.2 2.3e-11 44.1 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB02342.1 - 2.3e-21 75.9 0.4 9.3e-05 22.9 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB02342.1 - 3.1e-20 70.1 2.5 0.0011 19.3 0.1 6.2 4 2 2 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EGB02342.1 - 7.2e-18 64.4 0.3 0.004 17.4 0.0 5.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EGB02342.1 - 2.2e-11 43.7 1.2 0.21 12.1 0.1 5.4 5 1 0 5 5 5 3 Ankyrin repeat Clp_N PF02861.20 EGB02343.1 - 0.03 14.5 1.7 0.035 14.2 0.3 1.9 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component ERM PF00769.19 EGB02343.1 - 0.19 11.5 4.1 0.31 10.8 4.1 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family HAD PF12710.7 EGB02344.1 - 4.9e-11 43.4 0.4 1.2e-10 42.1 0.4 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EGB02344.1 - 1.3e-07 31.4 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EGB02344.1 - 4.9e-05 23.7 0.1 0.0048 17.2 0.1 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Acetyltransf_9 PF13527.7 EGB02345.1 - 5.8e-05 23.2 0.0 7.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB02345.1 - 0.0016 18.8 0.1 0.0023 18.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGB02345.1 - 0.0031 17.8 0.1 0.0042 17.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EGB02345.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Lactonase PF10282.9 EGB02346.1 - 4.3e-19 69.0 0.0 7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PH PF00169.29 EGB02346.1 - 5.6e-11 42.9 0.0 9.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGB02346.1 - 4.5e-05 23.6 0.1 0.00011 22.4 0.1 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGB02346.1 - 0.0048 17.3 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 EGB02346.1 - 0.056 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2148 PF09918.9 EGB02347.1 - 0.19 11.8 3.7 0.55 10.3 3.7 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) PT PF04886.12 EGB02349.1 - 5.2e-34 115.5 120.5 4.5e-06 26.1 3.0 8.2 2 1 2 4 4 4 3 PT repeat FG-GAP_2 PF14312.6 EGB02349.1 - 4.3e-29 100.5 64.9 6.4e-06 26.3 3.2 6.4 6 0 0 6 6 6 6 FG-GAP repeat HTH_43 PF09904.9 EGB02349.1 - 2.8e-07 30.4 16.1 0.29 11.1 0.1 6.0 6 0 0 6 6 6 4 Winged helix-turn helix Kelch_1 PF01344.25 EGB02349.1 - 2.6e-06 26.9 2.3 46 3.7 0.1 6.1 6 0 0 6 6 6 0 Kelch motif Kelch_6 PF13964.6 EGB02349.1 - 7.1e-05 22.9 9.1 3.2 8.2 0.1 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 EGB02349.1 - 0.01 15.8 12.8 7.1 6.7 0.1 5.6 6 0 0 6 6 6 0 Galactose oxidase, central domain CE2_N PF17996.1 EGB02349.1 - 0.026 14.5 5.3 5.6 7.0 0.0 5.0 5 1 1 6 6 6 0 Carbohydrate esterase 2 N-terminal Ran_BP1 PF00638.18 EGB02349.1 - 0.1 12.8 2.8 90 3.3 0.0 4.5 6 0 0 6 6 6 0 RanBP1 domain DUF3081 PF11280.8 EGB02349.1 - 0.3 10.9 3.0 39 4.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3081) DnaJ PF00226.31 EGB02350.1 - 4.7e-08 33.0 0.0 7.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DNA_binding_1 PF01035.20 EGB02350.1 - 0.083 13.0 0.8 0.39 10.9 0.1 2.1 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain LysM PF01476.20 EGB02351.1 - 2.1e-07 30.9 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 LysM domain UPF0176_N PF17773.1 EGB02352.1 - 1.3e-13 51.1 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain PhyH PF05721.13 EGB02353.1 - 2.6e-05 24.6 0.1 4.1e-05 23.9 0.0 1.4 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) AAA_5 PF07728.14 EGB02355.1 - 1.2e-29 103.0 0.0 2.8e-10 40.3 0.0 4.0 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_lid_5 PF17865.1 EGB02355.1 - 5.1e-10 39.4 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Midasin AAA lid domain AAA PF00004.29 EGB02355.1 - 1.1e-09 38.9 0.0 0.0017 18.8 0.0 3.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB02355.1 - 3.9e-06 27.4 9.1 0.0001 22.8 6.2 4.7 5 3 0 6 6 4 2 AAA ATPase domain Sigma54_activ_2 PF14532.6 EGB02355.1 - 4.2e-06 26.9 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 EGB02355.1 - 6e-06 26.3 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGB02355.1 - 6e-06 26.6 0.0 0.072 13.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EGB02355.1 - 6.1e-06 26.4 0.0 0.09 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGB02355.1 - 7.9e-06 25.9 0.1 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EGB02355.1 - 2.7e-05 24.5 0.0 0.0072 16.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGB02355.1 - 3.8e-05 24.2 0.0 0.5 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EGB02355.1 - 4.1e-05 23.4 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGB02355.1 - 5.7e-05 22.5 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.6 EGB02355.1 - 0.00032 21.1 0.2 0.086 13.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EGB02355.1 - 0.00032 20.2 0.0 0.019 14.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 EGB02355.1 - 0.00034 20.5 0.0 2 8.3 0.0 3.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGB02355.1 - 0.00039 19.7 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_25 PF13481.6 EGB02355.1 - 0.00049 19.7 4.3 0.11 12.1 0.0 4.6 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.21 EGB02355.1 - 0.00095 18.6 0.5 0.026 13.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Dynein_heavy PF03028.15 EGB02355.1 - 0.0024 17.9 0.0 0.048 13.7 0.0 2.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_30 PF13604.6 EGB02355.1 - 0.0066 16.2 2.0 0.33 10.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGB02355.1 - 0.0074 16.7 0.0 0.28 11.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 EGB02355.1 - 0.0098 15.9 0.0 5.9 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EGB02355.1 - 0.013 15.4 0.0 7.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein RuvB_N PF05496.12 EGB02355.1 - 0.013 15.2 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EGB02355.1 - 0.028 14.2 0.0 0.32 10.7 0.1 2.5 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EGB02355.1 - 0.028 14.8 0.0 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGB02355.1 - 0.035 14.6 0.0 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 EGB02355.1 - 0.041 13.6 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EGB02355.1 - 0.056 13.2 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EGB02355.1 - 0.071 12.1 0.0 12 4.8 0.0 3.2 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region Rad17 PF03215.15 EGB02355.1 - 0.073 13.0 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EGB02355.1 - 0.085 12.5 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EGB02355.1 - 0.094 12.5 0.0 2.1 8.1 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EGB02355.1 - 0.16 11.8 0.0 0.55 10.1 0.0 1.7 2 0 0 2 2 2 0 NTPase MobB PF03205.14 EGB02355.1 - 0.21 11.5 0.0 0.53 10.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TniB PF05621.11 EGB02355.1 - 0.24 10.8 0.0 0.67 9.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Cpn60_TCP1 PF00118.24 EGB02356.1 - 3.8e-78 263.3 1.8 4.2e-78 263.1 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HEAT_2 PF13646.6 EGB02357.1 - 5.2e-07 30.0 35.7 0.0095 16.3 9.4 5.3 2 1 4 6 6 6 6 HEAT repeats HEAT PF02985.22 EGB02357.1 - 0.0028 17.8 4.5 0.065 13.5 0.4 6.6 7 0 0 7 7 7 4 HEAT repeat Peptidase_C1 PF00112.23 EGB02359.1 - 3.1e-16 60.1 0.7 3.3e-16 60.1 0.7 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB02359.1 - 0.00092 18.1 0.8 0.00099 18.0 0.8 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Rad60-SLD PF11976.8 EGB02360.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sulfotransfer_1 PF00685.27 EGB02362.1 - 1.1e-14 54.5 0.0 1.5e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB02362.1 - 1.3e-05 25.7 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family TsaE PF02367.17 EGB02363.1 - 1.5e-25 89.6 0.0 1.7e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGB02363.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 EGB02363.1 - 0.21 10.9 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 KaiC Peptidase_S10 PF00450.22 EGB02364.1 - 1.4e-37 130.1 0.0 1.7e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Tubulin PF00091.25 EGB02366.1 - 1.8e-63 214.3 0.0 2.4e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB02366.1 - 1.1e-11 45.0 0.1 1.7e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain VCBS PF13517.6 EGB02367.1 - 7.2e-27 93.8 50.5 2.3e-09 37.7 5.3 3.8 1 1 3 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB02367.1 - 5e-18 64.9 33.7 0.00012 22.1 3.4 4.7 4 0 0 4 4 4 4 FG-GAP repeat BBS2_Mid PF14783.6 EGB02367.1 - 4.9e-06 26.5 0.0 0.91 9.6 0.0 4.0 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 EGB02367.1 - 0.0001 21.5 1.1 0.37 9.8 0.0 3.9 4 0 0 4 4 4 1 Integrin-alpha FG-GAP repeat-containing protein 2 BBS1 PF14779.6 EGB02367.1 - 0.013 15.0 0.8 44 3.4 0.0 3.9 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 1 TcdB_toxin_midN PF12256.8 EGB02367.1 - 0.36 10.2 12.9 2.9 7.2 0.0 3.7 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region Sel1 PF08238.12 EGB02368.1 - 1.5e-21 76.3 10.6 4.9e-08 33.4 0.2 4.4 4 1 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB02368.1 - 0.00025 21.6 7.5 0.013 16.2 1.1 3.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02368.1 - 0.0021 18.7 2.0 3.2 8.8 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02368.1 - 0.0053 17.3 6.2 3.1 8.6 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF977 PF06163.11 EGB02368.1 - 0.022 14.7 0.2 0.16 11.9 0.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF977) TPR_12 PF13424.6 EGB02368.1 - 0.061 13.6 0.2 0.061 13.6 0.2 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGB02368.1 - 0.07 13.2 2.1 2.3 8.4 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EGB02368.1 - 0.097 12.9 8.6 1.2 9.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02368.1 - 0.18 11.7 12.7 0.21 11.5 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02368.1 - 0.45 10.8 0.1 0.45 10.8 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02368.1 - 1.7 8.9 8.2 3.4 7.9 0.1 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 EGB02369.1 - 2.7e-08 33.9 0.1 6.1e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain AMP-binding PF00501.28 EGB02370.1 - 1e-20 73.7 0.1 1.7e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB02370.1 - 1.5e-18 67.5 0.3 2.1e-18 67.0 0.3 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Marek_SORF3 PF07153.11 EGB02370.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Na_H_Exchanger PF00999.21 EGB02371.1 - 2.1e-19 69.6 8.8 2.5e-19 69.3 8.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TPR_2 PF07719.17 EGB02371.1 - 0.016 15.3 0.1 0.049 13.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4010 PF13194.6 EGB02371.1 - 0.32 10.6 6.0 0.21 11.3 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) 4HFCP_synth PF04476.13 EGB02372.1 - 0.017 14.8 2.0 0.026 14.2 1.3 1.7 1 1 0 1 1 1 0 4-HFC-P synthase BAF250_C PF12031.8 EGB02372.1 - 0.028 13.7 0.3 0.063 12.6 0.3 1.6 1 1 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa DUF2207 PF09972.9 EGB02373.1 - 0.85 8.3 2.3 6.4 5.4 0.0 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) RskA PF10099.9 EGB02374.1 - 0.017 15.4 6.2 0.024 15.0 6.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Pkinase PF00069.25 EGB02375.1 - 2.3e-21 76.4 0.0 2.4e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02375.1 - 3.3e-12 46.2 0.0 4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB02375.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGB02375.1 - 0.15 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like SRP-alpha_N PF04086.13 EGB02376.1 - 9.3 6.1 10.3 12 5.8 10.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ketoacyl-synt PF00109.26 EGB02377.1 - 3e-12 46.7 3.3 3.3e-12 46.5 3.3 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF5455 PF17537.2 EGB02377.1 - 0.027 14.9 1.1 0.031 14.7 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5455) CD20 PF04103.15 EGB02377.1 - 0.028 14.5 4.5 0.031 14.4 4.5 1.0 1 0 0 1 1 1 0 CD20-like family SLATT_6 PF18169.1 EGB02377.1 - 0.055 13.1 1.4 0.06 12.9 1.4 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 SLATT_5 PF18160.1 EGB02377.1 - 0.95 8.7 4.1 1.1 8.6 4.1 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 HMG_CoA_synt_N PF01154.17 EGB02378.1 - 6.9e-22 78.1 0.1 7.5e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Ribonuc_red_lgC PF02867.15 EGB02379.1 - 6.6e-97 325.2 0.0 7.5e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGB02379.1 - 1.4e-17 63.5 0.1 3.7e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain DUF4116 PF13475.6 EGB02380.1 - 8.9e-13 47.8 0.0 1.5e-11 43.8 0.0 2.5 2 1 0 3 3 3 1 Domain of unknown function (DUF4116) ATP-synt_B PF00430.18 EGB02380.1 - 0.074 13.1 2.9 5.1 7.2 0.6 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Gal-3-0_sulfotr PF06990.11 EGB02381.1 - 0.055 12.3 0.4 0.083 11.8 0.4 1.3 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase PT PF04886.12 EGB02383.1 - 0.0088 15.6 4.0 0.0088 15.6 4.0 2.7 2 1 0 2 2 2 1 PT repeat FH2 PF02181.23 EGB02384.1 - 1.8e-22 80.0 0.0 2.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain LexA_DNA_bind PF01726.16 EGB02384.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HEAT_2 PF13646.6 EGB02385.1 - 1.3e-22 80.0 13.5 1.8e-09 37.9 0.3 3.2 2 1 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EGB02385.1 - 4.1e-15 54.9 20.2 0.012 16.2 0.7 5.7 5 0 0 5 5 5 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EGB02385.1 - 0.0013 18.8 1.4 7.7 7.1 0.0 4.8 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EGB02385.1 - 2.2 8.9 12.6 2.3 8.8 2.5 4.3 2 2 2 4 4 4 0 HEAT-like repeat RCC1 PF00415.18 EGB02386.1 - 4.7e-22 78.4 11.0 1.1e-05 26.0 0.0 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB02386.1 - 5.3e-10 38.8 23.3 0.00015 21.4 1.5 5.5 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Glyco_trans_1_2 PF13524.6 EGB02386.1 - 4.3e-05 23.8 0.0 0.00014 22.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 CDRN PF05174.12 EGB02386.1 - 0.13 12.0 0.1 0.52 10.0 0.1 2.1 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus DUF3089 PF11288.8 EGB02387.1 - 2.2e-53 180.8 0.0 2.9e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.8 EGB02387.1 - 0.00098 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Phage_holin_2_4 PF16082.5 EGB02387.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Abhydrolase_6 PF12697.7 EGB02387.1 - 5.5 7.5 22.5 0.35 11.5 13.9 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Glyco_hydro_28 PF00295.17 EGB02390.1 - 4.7e-06 25.9 1.3 1.1e-05 24.7 1.3 1.5 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EGB02390.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Right handed beta helix region Pkinase PF00069.25 EGB02391.1 - 1.1e-42 146.3 0.0 1.5e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02391.1 - 1.5e-24 86.7 0.0 1.9e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB02391.1 - 0.0055 15.7 0.2 0.0074 15.3 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB02391.1 - 0.0086 16.0 0.6 0.026 14.5 0.5 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB02391.1 - 0.016 14.5 0.4 0.028 13.8 0.3 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGB02391.1 - 0.13 11.9 0.0 0.43 10.2 0.0 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 cNMP_binding PF00027.29 EGB02393.1 - 0.00049 20.1 0.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain TPR_2 PF07719.17 EGB02393.1 - 0.0095 16.0 3.3 0.54 10.5 1.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Atrophin-1 PF03154.15 EGB02393.1 - 0.017 13.5 0.2 0.023 13.0 0.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Peptidase_S64 PF08192.11 EGB02393.1 - 0.1 11.1 0.1 0.15 10.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Sel1 PF08238.12 EGB02394.1 - 5.8e-37 125.3 20.9 5.8e-08 33.2 0.1 7.8 8 1 0 8 8 8 6 Sel1 repeat TPR_1 PF00515.28 EGB02394.1 - 0.00012 21.8 0.4 0.014 15.2 0.0 5.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB02394.1 - 0.0007 19.8 0.2 0.037 14.3 0.0 5.3 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGB02394.1 - 0.011 16.1 0.0 42 4.8 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF410 PF04190.13 EGB02394.1 - 0.036 13.9 0.8 1.9 8.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF410) TPR_10 PF13374.6 EGB02394.1 - 0.085 12.8 0.0 0.085 12.8 0.0 6.0 7 1 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02394.1 - 0.45 10.7 10.3 0.84 9.8 0.0 5.1 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02394.1 - 1.7 9.0 0.1 1.7 9.0 0.1 7.4 10 0 0 10 10 10 0 Tetratricopeptide repeat MIT PF04212.18 EGB02394.1 - 3.5 7.8 11.4 0.39 10.8 0.5 4.0 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EGB02394.1 - 3.7 8.0 16.6 1.5 9.3 0.1 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Nod1 PF17114.5 EGB02395.1 - 0.035 14.3 0.2 7.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 MitoNEET_N PF10660.9 EGB02395.1 - 0.039 14.0 0.2 25 5.0 0.0 3.2 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus Luteo_PO PF04662.13 EGB02395.1 - 0.21 11.2 0.1 78 2.8 0.0 3.3 2 2 2 4 4 4 0 Luteovirus P0 protein Na_Ca_ex PF01699.24 EGB02397.1 - 2.2e-26 92.6 7.5 2.6e-26 92.4 7.5 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Neurensin PF14927.6 EGB02397.1 - 0.15 11.8 2.6 0.92 9.2 0.3 2.1 2 0 0 2 2 2 0 Neurensin DUF3040 PF11239.8 EGB02397.1 - 1.9 8.8 4.9 6 7.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SUKH-3 PF14433.6 EGB02398.1 - 0.022 15.3 0.2 0.043 14.3 0.2 1.4 1 0 0 1 1 1 0 SUKH-3 immunity protein Wtap PF17098.5 EGB02400.1 - 0.0001 22.2 0.5 0.0002 21.3 0.0 1.7 3 0 0 3 3 3 1 WTAP/Mum2p family FUSC PF04632.12 EGB02400.1 - 2.4 6.6 5.9 2.9 6.3 5.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Kinesin PF00225.23 EGB02401.1 - 6.5e-120 400.0 0.0 7.4e-120 399.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB02401.1 - 9.6e-28 97.0 0.0 1.9e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 EGB02401.1 - 0.0002 21.5 0.5 0.0006 20.0 0.1 1.9 2 0 0 2 2 2 1 Kinesin-associated PIF1 PF05970.14 EGB02401.1 - 0.02 14.0 0.1 0.039 13.1 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase ketoacyl-synt PF00109.26 EGB02402.1 - 2e-45 155.4 2.8 2e-45 155.4 2.8 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB02402.1 - 5.6e-26 90.9 1.7 1e-25 90.1 1.7 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB02402.1 - 0.018 14.4 0.3 0.018 14.4 0.3 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGB02402.1 - 0.75 9.7 4.2 0.37 10.7 0.3 2.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 EGB02403.1 - 3.5e-49 167.0 0.0 4.2e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal FG-GAP_2 PF14312.6 EGB02404.1 - 2.9e-30 104.2 61.7 4.1e-06 26.9 3.7 6.2 6 0 0 6 6 6 6 FG-GAP repeat Kelch_6 PF13964.6 EGB02404.1 - 9.1e-11 41.6 7.8 0.91 9.9 0.1 5.2 5 0 0 5 5 5 4 Kelch motif HTH_43 PF09904.9 EGB02404.1 - 4.7e-09 36.1 11.1 0.16 11.9 0.1 5.1 5 0 0 5 5 5 3 Winged helix-turn helix Kelch_1 PF01344.25 EGB02404.1 - 1.4e-06 27.7 0.4 27 4.4 0.0 5.3 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 EGB02404.1 - 9.8e-05 22.3 9.5 7.4 6.7 0.1 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain CE2_N PF17996.1 EGB02404.1 - 0.00052 20.0 4.9 13 5.9 0.0 5.2 5 1 1 6 6 6 1 Carbohydrate esterase 2 N-terminal T3SS_ExsE PF18286.1 EGB02404.1 - 0.0096 15.8 0.0 36 4.4 0.0 4.7 5 0 0 5 5 5 0 Type III secretion system ExsE DUF3081 PF11280.8 EGB02404.1 - 0.06 13.2 6.1 57 3.7 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3081) HalOD1 PF18545.1 EGB02404.1 - 0.076 13.3 0.1 45 4.4 0.0 4.0 5 0 0 5 5 5 0 Halobacterial output domain 1 Ran_BP1 PF00638.18 EGB02404.1 - 0.093 13.0 0.8 2.4e+02 2.0 0.0 4.2 5 0 0 5 5 5 0 RanBP1 domain LEA_2 PF03168.13 EGB02404.1 - 1.2 9.7 9.1 68 4.1 0.1 4.7 5 0 0 5 5 5 0 Late embryogenesis abundant protein PD40 PF07676.12 EGB02404.1 - 2.4 8.2 10.8 88 3.2 0.0 6.2 7 1 0 7 7 7 0 WD40-like Beta Propeller Repeat Lsr2 PF11774.8 EGB02404.1 - 2.5 8.3 13.3 27 5.0 0.2 5.5 6 0 0 6 6 6 0 Lsr2 DUF3833 PF12915.7 EGB02404.1 - 4.8 6.8 11.0 22 4.6 0.1 4.5 3 1 2 5 5 5 0 Protein of unknown function (DUF3833) Ribosomal_S19e PF01090.19 EGB02405.1 - 1.5e-49 167.2 0.2 1.6e-49 167.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 EGB02405.1 - 0.053 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain MFS_1 PF07690.16 EGB02406.1 - 9.6e-05 21.5 11.3 0.00012 21.1 11.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Imp-YgjV PF10688.9 EGB02406.1 - 0.094 12.5 0.2 0.094 12.5 0.2 1.6 2 0 0 2 2 2 0 Bacterial inner membrane protein DNA_pol_B_thumb PF14791.6 EGB02408.1 - 1.9e-12 47.1 1.0 6.9e-06 26.1 0.1 2.4 2 0 0 2 2 2 2 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EGB02408.1 - 0.00063 19.9 0.0 0.0011 19.1 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase beta palm NTP_transf_2 PF01909.23 EGB02408.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain Tachystatin_B PF11478.8 EGB02409.1 - 6.7 6.7 12.0 3.8 7.5 4.8 2.5 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B Ank_2 PF12796.7 EGB02410.1 - 1.5e-12 47.9 0.0 6.6e-09 36.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB02410.1 - 3.4e-12 45.4 0.9 3.7e-05 23.8 0.0 4.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGB02410.1 - 6.6e-07 29.5 2.1 0.054 13.8 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB02410.1 - 6.5e-06 26.6 0.9 0.03 14.9 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB02410.1 - 0.00015 22.1 0.7 0.61 10.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat F-box PF00646.33 EGB02412.1 - 1.6e-06 27.8 0.9 2.4e-06 27.3 0.9 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGB02412.1 - 5.2e-06 26.3 0.3 1e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 F-box-like bZIP_2 PF07716.15 EGB02412.1 - 0.021 14.9 0.5 0.035 14.2 0.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 EGB02412.1 - 0.035 14.2 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor KR PF08659.10 EGB02414.1 - 1.1e-16 61.2 8.9 2.7e-11 43.7 1.8 3.1 2 1 1 3 3 3 2 KR domain PP-binding PF00550.25 EGB02414.1 - 1.1e-05 25.7 0.2 7.2e-05 23.1 0.5 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.25 EGB02414.1 - 0.0066 15.9 0.5 0.019 14.4 0.5 1.8 1 0 0 1 1 1 1 short chain dehydrogenase DNA_methylase PF00145.17 EGB02416.1 - 4.5e-10 39.4 0.0 6.5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase His_Phos_1 PF00300.22 EGB02418.1 - 5.9e-11 42.4 0.3 9.4e-11 41.8 0.3 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RimK PF08443.11 EGB02420.1 - 6.2e-06 25.9 0.0 8.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp PF02222.22 EGB02420.1 - 0.018 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 EGB02420.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Ras PF00071.22 EGB02421.1 - 7.9e-56 188.1 0.1 9.7e-56 187.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB02421.1 - 2.4e-36 124.6 0.1 3.2e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB02421.1 - 1.1e-13 51.0 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB02421.1 - 0.00011 21.6 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGB02421.1 - 0.00011 22.1 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGB02421.1 - 0.00028 20.5 0.0 0.0015 18.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGB02421.1 - 0.00036 20.0 0.0 0.00071 19.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGB02421.1 - 0.00085 19.4 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EGB02421.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EGB02421.1 - 0.011 15.6 0.0 0.046 13.5 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TIR_2 PF13676.6 EGB02421.1 - 0.016 15.8 0.1 0.025 15.2 0.1 1.2 1 0 0 1 1 1 0 TIR domain DUF1863 PF08937.11 EGB02421.1 - 0.03 14.7 0.1 0.66 10.3 0.1 2.1 1 1 1 2 2 2 0 MTH538 TIR-like domain (DUF1863) AAA_22 PF13401.6 EGB02421.1 - 0.045 14.0 0.0 0.71 10.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 EGB02421.1 - 0.12 11.9 0.1 3 7.4 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B SH3_9 PF14604.6 EGB02422.1 - 1e-06 28.5 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGB02422.1 - 6.4e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB02422.1 - 0.00011 21.7 0.4 0.0011 18.6 0.4 2.1 1 1 0 1 1 1 1 SH3 domain bZIP_2 PF07716.15 EGB02423.1 - 8.4e-06 25.8 7.3 1.8e-05 24.7 7.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGB02423.1 - 4.9e-05 23.3 6.9 0.0001 22.3 6.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF3395 PF11875.8 EGB02423.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) DUF3410 PF11890.8 EGB02424.1 - 0.0069 16.2 0.6 0.012 15.4 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3410) TIL PF01826.17 EGB02427.1 - 3.3 8.0 14.5 0.32 11.3 9.5 2.0 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Glyco_transf_25 PF01755.17 EGB02429.1 - 0.0011 18.8 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Acetyltransf_1 PF00583.25 EGB02431.1 - 4.5e-10 39.8 0.0 5.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGB02431.1 - 2.1e-08 34.5 0.0 3.1e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGB02431.1 - 3.5e-07 30.2 0.0 5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB02431.1 - 4.9e-06 26.4 0.0 7.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGB02431.1 - 0.00021 22.0 0.0 0.00031 21.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGB02431.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EGB02431.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Thymidylate_kin PF02223.17 EGB02432.1 - 3.4e-44 150.7 0.0 4e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CobU PF02283.16 EGB02432.1 - 0.045 13.3 0.2 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Helicase_C PF00271.31 EGB02434.1 - 1.3e-17 64.1 0.0 2.4e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGB02434.1 - 7.4e-05 22.1 0.0 0.00016 21.0 0.0 1.5 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase EII-Sor PF03609.14 EGB02434.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 PTS system sorbose-specific iic component MAGUK_N_PEST PF10608.9 EGB02435.1 - 8.7 6.8 8.5 0.85 10.1 2.3 2.2 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Rrn6 PF10214.9 EGB02435.1 - 9.4 4.6 11.5 11 4.3 11.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor adh_short PF00106.25 EGB02436.1 - 1.5e-05 24.6 0.3 2e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB02436.1 - 0.049 13.6 0.2 0.088 12.7 0.2 1.4 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 EGB02436.1 - 0.13 12.1 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aminotran_1_2 PF00155.21 EGB02437.1 - 6.4e-18 65.1 0.4 2.5e-16 59.8 0.4 2.7 1 1 0 1 1 1 1 Aminotransferase class I and II Complex1_LYR PF05347.15 EGB02439.1 - 1.8e-11 43.9 0.6 3.3e-11 43.0 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Lig_chan PF00060.26 EGB02439.1 - 7.2e-09 35.7 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Complex1_LYR_2 PF13233.6 EGB02439.1 - 0.024 15.4 0.0 0.045 14.5 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Mannosyl_trans3 PF11051.8 EGB02441.1 - 0.00036 20.0 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative RBM1CTR PF08081.11 EGB02442.1 - 4.1 7.5 7.4 0.48 10.5 1.4 2.2 2 0 0 2 2 2 0 RBM1CTR (NUC064) family ABC1 PF03109.16 EGB02444.1 - 2.3e-15 56.8 0.0 4.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Helicase_C PF00271.31 EGB02445.1 - 5.2e-25 88.0 0.0 6.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PC_rep PF01851.22 EGB02446.1 - 3.9e-34 115.4 11.3 4.5e-09 36.3 0.0 6.7 6 0 0 6 6 6 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGB02446.1 - 1.5e-16 60.6 2.7 1.9e-12 47.4 0.0 4.4 2 1 3 5 5 5 2 HEAT repeats HEAT PF02985.22 EGB02446.1 - 1.7e-07 30.9 3.1 0.67 10.4 0.2 6.0 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 EGB02446.1 - 0.0019 18.7 6.2 0.33 11.5 0.1 5.2 2 2 3 5 5 5 2 HEAT-like repeat IBN_N PF03810.19 EGB02446.1 - 0.0043 16.9 0.0 1.3 9.0 0.0 3.6 3 1 0 3 3 3 1 Importin-beta N-terminal domain TPR_16 PF13432.6 EGB02446.1 - 2.1 9.1 4.5 4.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Tctex-1 PF03645.13 EGB02447.1 - 4.1e-17 62.3 0.0 4.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family 2OG-FeII_Oxy_3 PF13640.6 EGB02448.1 - 2.7e-15 57.0 0.0 4.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB02448.1 - 1.2e-08 35.5 0.0 1.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EGB02448.1 - 0.014 15.6 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) SelK_SelG PF10961.8 EGB02449.1 - 3.3e-21 75.7 5.1 5e-21 75.1 5.1 1.3 1 1 0 1 1 1 1 Selenoprotein SelK_SelG FoP_duplication PF13865.6 EGB02449.1 - 0.13 12.8 5.6 0.17 12.4 5.6 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DEAD PF00270.29 EGB02451.1 - 5.2e-21 75.2 0.1 6.4e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB02451.1 - 0.0029 17.6 0.0 0.0043 17.1 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EGB02451.1 - 0.048 13.2 1.5 0.098 12.2 1.5 1.7 1 1 0 1 1 1 0 AAA domain CCER1 PF15482.6 EGB02452.1 - 0.21 11.5 0.1 0.41 10.5 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 LRR_6 PF13516.6 EGB02454.1 - 3.2e-10 39.2 0.2 0.02 14.9 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 EGB02454.1 - 2.3e-08 34.2 0.0 0.052 14.0 0.0 3.3 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB02454.1 - 0.009 16.4 2.1 1.6e+02 3.5 0.0 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat FG-GAP_2 PF14312.6 EGB02457.1 - 4.3e-26 90.9 50.6 1e-05 25.7 3.3 5.3 5 0 0 5 5 5 5 FG-GAP repeat HTH_43 PF09904.9 EGB02457.1 - 7.2e-07 29.1 5.5 4.1 7.4 0.1 4.4 4 0 0 4 4 4 4 Winged helix-turn helix Lsr2 PF11774.8 EGB02457.1 - 0.0011 19.1 9.0 20 5.4 0.1 5.2 5 0 0 5 5 5 1 Lsr2 Kelch_1 PF01344.25 EGB02457.1 - 0.0013 18.3 1.8 21 4.8 0.1 4.1 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 EGB02457.1 - 0.026 14.8 7.4 3.7 8.0 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 EGB02457.1 - 0.47 10.5 3.3 15 5.7 0.0 3.3 4 0 0 4 4 4 0 Galactose oxidase, central domain PFU PF09070.11 EGB02457.1 - 0.81 10.0 5.8 1e+02 3.2 0.0 4.0 4 0 0 4 4 4 0 PFU (PLAA family ubiquitin binding) FG-GAP PF01839.23 EGB02457.1 - 5.1 7.3 24.9 2.4 8.4 0.3 5.7 5 0 0 5 5 5 0 FG-GAP repeat LEA_2 PF03168.13 EGB02457.1 - 6.1 7.5 5.6 92 3.7 0.0 4.0 5 0 0 5 5 5 0 Late embryogenesis abundant protein PQQ_2 PF13360.6 EGB02458.1 - 1.7e-33 116.2 7.5 5.6e-20 71.9 2.8 2.0 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 EGB02458.1 - 4.3e-31 106.6 34.2 3.1e-10 40.2 0.4 6.4 6 1 0 6 6 6 5 PQQ-like domain PQQ PF01011.21 EGB02458.1 - 5.3e-28 95.6 8.4 2.5e-06 27.1 0.0 6.1 6 0 0 6 6 6 4 PQQ enzyme repeat CRM1_C PF08767.11 EGB02459.1 - 1.1e-67 228.5 0.0 1.6e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 CRM1 C terminal DUF4346 PF14251.6 EGB02461.1 - 0.076 13.1 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) DEAD PF00270.29 EGB02463.1 - 2.7e-40 138.0 0.0 3.8e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB02463.1 - 2.9e-28 98.4 0.7 1.2e-27 96.5 0.6 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB02463.1 - 8.7e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGB02463.1 - 0.0019 17.4 0.1 0.0026 17.0 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EGB02463.1 - 0.017 14.5 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EGB02463.1 - 0.16 12.3 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DS PF01916.17 EGB02463.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase JAB PF01398.21 EGB02464.1 - 9.1e-17 61.1 0.0 1.9e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGB02464.1 - 9.9e-10 38.8 0.3 1.5e-09 38.2 0.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JLPA PF16668.5 EGB02464.1 - 0.038 13.0 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Adhesin from Campylobacter Prok-JAB PF14464.6 EGB02464.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain WRNPLPNID PF15017.6 EGB02465.1 - 2.1 9.3 8.8 13 6.8 0.9 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Hydrolase_3 PF08282.12 EGB02466.1 - 1.1e-31 110.6 0.0 1.3e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGB02466.1 - 8.4e-09 35.3 0.0 5e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EGB02466.1 - 1.5e-08 35.2 5.0 2.8e-08 34.3 5.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ArabFuran-catal PF09206.11 EGB02467.1 - 1.3e-114 382.7 7.4 2.2e-114 382.0 7.4 1.3 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic bPH_2 PF03703.14 EGB02468.1 - 8e-13 48.4 0.1 9.9e-13 48.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial PH domain Lectin_legB PF00139.19 EGB02468.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Legume lectin domain DUF1778 PF08681.11 EGB02469.1 - 0.14 12.1 1.6 1 9.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1778) TPR_12 PF13424.6 EGB02470.1 - 1.3e-39 134.3 20.2 2e-15 56.8 2.8 4.0 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02470.1 - 8.6e-31 104.9 23.4 3e-09 36.5 0.5 5.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02470.1 - 9.6e-12 44.1 12.0 2e-05 24.3 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02470.1 - 1.5e-11 43.5 6.1 0.001 19.1 0.0 4.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02470.1 - 4.2e-11 42.2 10.7 0.00067 19.4 0.1 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02470.1 - 1.2e-09 37.5 9.9 0.00033 20.5 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 EGB02470.1 - 7.6e-05 23.0 2.6 2.3 9.1 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02470.1 - 0.00046 20.8 7.9 0.21 12.3 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.7 EGB02470.1 - 0.0019 18.5 3.6 1.2 9.4 0.1 3.7 1 1 3 4 4 4 1 Tetratrico peptide repeat TPR_14 PF13428.6 EGB02470.1 - 0.0027 18.4 4.2 0.72 10.8 0.0 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02470.1 - 0.0048 17.5 1.2 9.4 7.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB02470.1 - 0.0099 16.2 6.5 17 6.1 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF4807 PF16065.5 EGB02470.1 - 0.012 15.3 0.4 16 5.2 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4807) DUF1955 PF09205.10 EGB02470.1 - 0.078 12.7 0.0 20 4.9 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1955) Fis1_TPR_C PF14853.6 EGB02470.1 - 0.097 12.8 0.2 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CARDB PF07705.11 EGB02470.1 - 0.14 12.4 0.0 8 6.8 0.0 3.1 4 0 0 4 4 4 0 CARDB TPR_11 PF13414.6 EGB02470.1 - 0.15 11.8 12.6 0.56 9.9 0.1 4.8 4 1 1 5 5 5 0 TPR repeat DUF5471 PF17565.2 EGB02470.1 - 0.58 10.5 2.1 18 5.7 0.2 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5471) PH PF00169.29 EGB02472.1 - 8.4e-08 32.7 0.0 1.1e-06 29.1 0.0 2.6 3 0 0 3 3 3 1 PH domain PDZ_6 PF17820.1 EGB02472.1 - 0.0002 21.2 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 EGB02472.1 - 0.0036 17.7 0.0 1.2 9.6 0.0 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain Ribosomal_L7Ae PF01248.26 EGB02473.1 - 1.7e-23 82.2 0.6 2e-23 81.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MAPEG PF01124.18 EGB02474.1 - 3.6e-06 26.9 1.3 7.4e-06 25.9 1.3 1.5 1 0 0 1 1 1 1 MAPEG family MBD PF01429.19 EGB02474.1 - 0.0006 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain zf-CXXC PF02008.20 EGB02474.1 - 0.21 11.6 14.5 0.69 10.0 14.5 1.8 1 1 0 1 1 1 0 CXXC zinc finger domain WD40 PF00400.32 EGB02475.1 - 7.9e-33 112.0 10.6 6e-08 33.2 0.2 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB02475.1 - 7.2e-05 23.0 0.2 2.2 8.7 0.0 3.7 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB02475.1 - 0.00038 19.2 3.9 4.3 5.8 0.0 4.2 3 1 2 5 5 5 3 Nucleoporin Nup120/160 A_deamin PF02137.18 EGB02476.1 - 1.5e-25 90.3 0.0 5.2e-21 75.4 0.0 2.2 1 1 1 2 2 2 2 Adenosine-deaminase (editase) domain dCMP_cyt_deam_1 PF00383.23 EGB02476.1 - 0.0012 18.7 0.1 0.0022 17.8 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGB02476.1 - 0.059 13.1 0.1 0.096 12.4 0.1 1.3 1 0 0 1 1 1 0 MafB19-like deaminase FKBP_C PF00254.28 EGB02477.1 - 1.7e-28 98.8 0.0 1.9e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FAA_hydrolase PF01557.18 EGB02478.1 - 0.0039 16.9 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DAP10 PF07213.11 EGB02480.1 - 0.4 10.7 4.1 0.37 10.8 2.6 1.8 1 1 0 1 1 1 0 DAP10 membrane protein Pkinase PF00069.25 EGB02481.1 - 1.3e-75 254.2 0.0 1.5e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02481.1 - 4e-31 108.3 0.0 4.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB02481.1 - 0.00054 19.4 0.0 0.0014 18.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB02481.1 - 0.0025 17.2 0.2 0.0035 16.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB02481.1 - 0.0071 15.2 0.0 0.0098 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGB02481.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EGB02481.1 - 0.086 12.8 0.2 2.6 7.9 0.1 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGB02481.1 - 0.095 12.3 0.0 0.13 11.8 0.0 1.3 1 1 0 1 1 1 0 RIO1 family CsgA PF17334.2 EGB02481.1 - 0.099 13.4 0.0 1.8 9.4 0.0 2.4 2 0 0 2 2 2 0 Minor curli fiber component A RRM_1 PF00076.22 EGB02482.1 - 3.1e-10 39.7 0.0 5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB02482.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif eIF3g PF12353.8 EGB02482.1 - 0.19 12.1 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G CAP_N PF01213.19 EGB02482.1 - 2.4 7.5 8.5 3.8 6.9 8.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Herpes_UL52 PF03121.15 EGB02483.1 - 0.07 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase TALPID3 PF15324.6 EGB02483.1 - 7.7 4.0 6.2 11 3.6 6.2 1.1 1 0 0 1 1 1 0 Hedgehog signalling target SR-25 PF10500.9 EGB02484.1 - 0.025 14.2 2.7 0.042 13.5 2.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mito_fiss_reg PF05308.11 EGB02484.1 - 2.7 8.0 9.4 13 5.8 9.5 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator MFS_1 PF07690.16 EGB02486.1 - 1.6e-25 89.8 15.3 1.6e-25 89.8 15.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB02486.1 - 5.5e-08 32.1 5.5 8.6e-08 31.5 5.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EGB02486.1 - 0.00013 20.4 0.3 0.0002 19.8 0.3 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SLIDE PF09111.10 EGB02487.1 - 5e-34 116.7 0.0 4.5e-32 110.4 0.0 2.1 2 0 0 2 2 2 2 SLIDE Myb_DNA-binding PF00249.31 EGB02487.1 - 3.1e-06 27.3 0.0 0.036 14.3 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB02487.1 - 0.0024 18.1 0.0 0.25 11.6 0.0 2.9 3 1 0 3 3 3 1 Myb-like DNA-binding domain APG6_N PF17675.1 EGB02487.1 - 0.33 11.5 3.9 21 5.6 1.1 2.6 2 1 1 3 3 3 0 Apg6 coiled-coil region Aldo_ket_red PF00248.21 EGB02488.1 - 1.8e-09 37.3 0.0 2.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family TTL PF03133.15 EGB02489.1 - 5.7e-20 71.6 0.0 7.4e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Ferric_reduct PF01794.19 EGB02489.1 - 0.015 15.4 7.9 0.028 14.5 7.9 1.5 1 0 0 1 1 1 0 Ferric reductase like transmembrane component WCOR413 PF05562.11 EGB02489.1 - 0.12 12.4 1.3 0.18 11.7 0.9 1.5 1 1 0 1 1 1 0 Cold acclimation protein WCOR413 SAP PF02037.27 EGB02490.1 - 4.4e-09 35.9 0.6 8.5e-09 35.0 0.6 1.5 1 0 0 1 1 1 1 SAP domain Na_H_Exchanger PF00999.21 EGB02491.1 - 1.1e-13 50.8 1.5 1.2e-13 50.7 1.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3653 PF12375.8 EGB02493.1 - 0.021 14.9 0.0 31 4.8 0.0 3.4 3 1 0 3 3 3 0 Phage protein Methyltransf_25 PF13649.6 EGB02494.1 - 2e-11 44.4 0.1 7.7e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGB02494.1 - 2.5e-11 44.1 0.4 0.00012 22.7 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGB02494.1 - 2.9e-07 30.5 0.0 0.012 15.4 0.0 3.4 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_24 PF13578.6 EGB02494.1 - 3.8e-05 24.6 0.0 0.13 13.2 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02494.1 - 0.0094 15.7 0.0 0.05 13.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EGB02494.1 - 0.019 14.7 0.4 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGB02494.1 - 0.032 15.0 0.0 7.4 7.4 0.0 2.8 2 2 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 EGB02494.1 - 0.099 11.7 0.0 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase VKG_Carbox PF05090.14 EGB02495.1 - 0.00019 20.4 0.0 0.00027 19.9 0.0 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Methyltransf_11 PF08241.12 EGB02495.1 - 0.0026 18.4 0.0 0.0058 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGB02495.1 - 0.073 14.1 0.1 0.65 11.0 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02495.1 - 0.084 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_32N PF00251.20 EGB02496.1 - 0.0029 17.2 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Ras PF00071.22 EGB02498.1 - 1.5e-36 125.4 0.0 1.8e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB02498.1 - 9e-21 74.3 0.0 1.2e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB02498.1 - 4.1e-12 45.9 0.0 5.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB02498.1 - 5.5e-07 29.2 0.0 6.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB02498.1 - 0.00036 20.6 0.0 0.00047 20.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB02498.1 - 0.00067 19.3 0.0 0.0016 18.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EGB02498.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit JmjC PF02373.22 EGB02501.1 - 5.7e-05 23.5 0.0 0.00016 22.1 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGB02501.1 - 0.085 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein RmlD_sub_bind PF04321.17 EGB02502.1 - 1.8e-21 76.5 0.0 8.5e-20 71.0 0.0 2.3 1 1 1 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 EGB02502.1 - 1.2e-19 70.8 0.0 2.2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGB02502.1 - 0.00019 21.7 0.2 0.0012 19.1 0.0 2.4 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGB02502.1 - 0.00055 19.9 0.4 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGB02502.1 - 0.047 12.8 0.0 4.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Glutaredoxin2_C PF04399.13 EGB02503.1 - 1.1e-37 128.7 0.0 9.6e-36 122.5 0.0 2.0 1 1 0 1 1 1 1 Glutaredoxin 2, C terminal domain NinF PF05810.12 EGB02503.1 - 0.0024 17.7 0.2 0.004 17.0 0.2 1.3 1 0 0 1 1 1 1 NinF protein N6_Mtase PF02384.16 EGB02503.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Myosin_head PF00063.21 EGB02504.1 - 3.2e-19 68.6 0.0 3.4e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) FtsJ PF01728.19 EGB02505.1 - 3e-36 125.2 0.0 3.4e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase E1-N PF14463.6 EGB02505.1 - 0.0014 18.5 2.2 0.0018 18.1 2.2 1.2 1 0 0 1 1 1 1 E1 N-terminal domain Methyltransf_23 PF13489.6 EGB02505.1 - 0.0047 16.8 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EGB02505.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 EGB02505.1 - 0.1 13.3 0.0 0.35 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain tRNA-synt_2b PF00587.25 EGB02506.1 - 4.1e-42 144.2 0.0 6.1e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGB02506.1 - 2.3e-15 56.5 0.0 4.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain DNA_pol_A_exo1 PF01612.20 EGB02507.1 - 4.6e-07 29.7 0.0 7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Heme_oxygenase PF01126.20 EGB02509.1 - 6.4e-28 97.9 0.0 8.4e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase 2-oxoacid_dh PF00198.23 EGB02510.1 - 1.9e-63 214.1 0.0 2.9e-63 213.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EGB02510.1 - 2.8e-15 56.4 2.4 7.9e-15 54.9 2.4 1.9 1 0 0 1 1 1 1 e3 binding domain GATase_6 PF13522.6 EGB02511.1 - 4.7e-06 26.8 0.2 9.3e-06 25.9 0.2 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain Peptidase_C48 PF02902.19 EGB02512.1 - 6e-19 68.7 0.0 7.1e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DnaJ PF00226.31 EGB02513.1 - 9.6e-22 76.9 0.0 1.1e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain HEAT_EZ PF13513.6 EGB02515.1 - 0.03 14.8 0.3 24 5.6 0.0 3.1 2 1 1 3 3 3 0 HEAT-like repeat CLASP_N PF12348.8 EGB02516.1 - 6.5e-08 32.4 0.0 4e-06 26.6 0.0 2.3 1 1 1 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.6 EGB02516.1 - 0.00019 21.9 1.8 0.31 11.6 0.0 4.1 2 2 3 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EGB02516.1 - 0.00059 19.9 0.2 0.22 11.9 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EGB02516.1 - 0.0026 18.1 0.8 0.36 11.3 0.0 3.1 1 1 0 2 2 2 1 HEAT repeats DUF3437 PF11919.8 EGB02516.1 - 0.0041 17.0 0.3 0.069 13.1 0.0 2.4 1 1 2 3 3 3 1 Domain of unknown function (DUF3437) NUC173 PF08161.12 EGB02516.1 - 0.095 12.3 0.3 4 7.0 0.0 2.7 1 1 2 3 3 3 0 NUC173 domain FAM176 PF14851.6 EGB02517.1 - 0.28 10.8 0.0 0.28 10.8 0.0 3.4 3 1 0 3 3 3 0 FAM176 family ATP-synt_B PF00430.18 EGB02519.1 - 0.57 10.3 6.5 1.1 9.3 6.5 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CLU PF13236.6 EGB02520.1 - 1.8e-33 116.3 0.0 2.4e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Clustered mitochondria Vac14_Fig4_bd PF11916.8 EGB02522.1 - 4.4e-71 238.2 9.2 4.4e-71 238.2 9.2 1.6 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding CLASP_N PF12348.8 EGB02522.1 - 1.9e-06 27.6 0.0 4.6e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 EGB02522.1 - 2.4e-06 27.3 0.2 0.46 10.9 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGB02522.1 - 2.3e-05 24.9 0.2 3.1 8.5 0.1 3.5 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGB02522.1 - 0.00013 22.4 0.3 0.21 12.1 0.1 3.0 2 1 0 2 2 2 2 HEAT-like repeat Cnd1 PF12717.7 EGB02522.1 - 0.00025 21.1 0.9 1.1 9.3 0.0 3.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGB02522.1 - 0.05 14.0 0.3 11 6.5 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats Med16 PF11635.8 EGB02522.1 - 0.083 10.8 0.3 0.56 8.0 0.6 1.9 2 0 0 2 2 2 0 Mediator complex subunit 16 FTHFS PF01268.19 EGB02523.1 - 8.1e-44 149.8 0.0 8.9e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Gly_rich_SFCGS PF14272.6 EGB02523.1 - 0.063 13.3 0.1 0.083 12.9 0.1 1.2 1 0 0 1 1 1 0 Glycine-rich SFCGS PDZ PF00595.24 EGB02524.1 - 0.00025 21.3 0.0 0.0004 20.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.25 EGB02525.1 - 4.8e-69 232.6 0.0 5.4e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02525.1 - 9.6e-37 126.7 0.0 1.1e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB02525.1 - 7.7e-06 25.4 0.0 8.9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB02525.1 - 0.15 11.4 0.3 0.22 10.8 0.3 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop PF01798.18 EGB02526.1 - 5.9e-64 215.7 0.0 8.5e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Lysine_decarbox PF03641.14 EGB02527.1 - 2.7e-23 82.5 0.0 3.4e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EGB02527.1 - 1.1e-15 57.6 0.5 1.4e-15 57.3 0.5 1.2 1 0 0 1 1 1 1 SLOG cluster4 family Big_10 PF17964.1 EGB02529.1 - 0.14 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial Ig domain Nup88 PF10168.9 EGB02529.1 - 0.35 8.6 2.5 0.55 8.0 2.5 1.2 1 0 0 1 1 1 0 Nuclear pore component SYCE1 PF15233.6 EGB02529.1 - 5 7.2 6.5 2.2 8.3 3.5 1.9 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 SBF_like PF13593.6 EGB02530.1 - 2.6e-09 36.8 0.4 2.9e-09 36.7 0.4 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) YrhC PF14143.6 EGB02530.1 - 0.072 13.2 0.3 0.45 10.6 0.0 2.0 1 1 1 2 2 2 0 YrhC-like protein YHYH PF14240.6 EGB02531.1 - 1.9e-10 41.0 0.2 2.3e-06 27.7 0.1 2.3 1 1 1 2 2 2 2 YHYH protein HET PF06985.11 EGB02531.1 - 0.046 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) MIF4G PF02854.19 EGB02533.1 - 4.8e-30 104.8 0.0 1.3e-29 103.3 0.0 1.7 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EGB02533.1 - 0.0013 18.7 0.0 0.0052 16.8 0.0 2.0 2 0 0 2 2 2 1 MA3 domain TPR_12 PF13424.6 EGB02534.1 - 2.2e-33 114.4 23.4 3.1e-10 40.2 0.6 3.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02534.1 - 2.1e-27 94.1 17.2 8.4e-07 28.7 0.3 5.9 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02534.1 - 5.2e-11 41.8 11.6 0.034 14.2 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02534.1 - 4.5e-10 38.9 7.4 0.31 11.3 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02534.1 - 2.6e-07 30.2 8.8 0.21 11.4 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02534.1 - 6.2e-05 22.8 10.0 0.99 9.7 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02534.1 - 0.00027 21.5 8.5 2.1 9.4 0.3 4.5 3 2 2 5 5 4 2 Tetratricopeptide repeat DUF4807 PF16065.5 EGB02534.1 - 0.001 18.7 2.3 4.6 6.9 0.0 3.6 1 1 3 4 4 4 1 Domain of unknown function (DUF4807) Mob_Pre PF01076.19 EGB02534.1 - 0.0061 16.4 0.0 0.28 11.0 0.0 2.2 2 0 0 2 2 2 1 Plasmid recombination enzyme XdhC_CoxI PF02625.16 EGB02534.1 - 0.014 15.6 0.4 52 4.1 0.0 3.5 2 1 1 3 3 3 0 XdhC and CoxI family TPR_6 PF13174.6 EGB02534.1 - 0.074 13.7 5.1 3 8.7 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat NuA4 PF09340.10 EGB02534.1 - 0.15 12.0 0.4 3.1 7.7 0.1 2.5 2 1 1 3 3 3 0 Histone acetyltransferase subunit NuA4 TPR_9 PF13371.6 EGB02534.1 - 0.25 11.5 4.5 0.9 9.7 1.2 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB02534.1 - 2.5 8.7 4.6 29 5.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGB02534.1 - 3 8.7 10.1 19 6.3 0.4 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat FG-GAP_2 PF14312.6 EGB02535.1 - 2.8e-27 94.7 64.1 3e-06 27.4 3.1 6.6 6 0 0 6 6 6 6 FG-GAP repeat HTH_43 PF09904.9 EGB02535.1 - 1.6e-05 24.7 9.7 4 7.5 0.1 5.1 5 0 0 5 5 5 2 Winged helix-turn helix CE2_N PF17996.1 EGB02535.1 - 0.13 12.3 0.5 26 4.9 0.0 3.2 3 0 0 3 3 3 0 Carbohydrate esterase 2 N-terminal Kelch_6 PF13964.6 EGB02535.1 - 0.21 12.0 6.4 4.4 7.7 0.0 4.3 5 0 0 5 5 5 0 Kelch motif DUF3833 PF12915.7 EGB02535.1 - 0.22 11.1 20.9 1.7 8.2 0.4 4.8 2 1 4 6 6 6 0 Protein of unknown function (DUF3833) Lsr2 PF11774.8 EGB02535.1 - 0.41 10.8 16.0 50 4.1 0.0 6.0 6 0 0 6 6 6 0 Lsr2 Ran_BP1 PF00638.18 EGB02535.1 - 0.57 10.5 1.0 3.7e+02 1.4 0.0 4.1 5 0 0 5 5 5 0 RanBP1 domain PT PF04886.12 EGB02535.1 - 1 8.9 56.0 1.4e+03 -1.1 50.9 2.7 2 1 0 2 2 2 0 PT repeat adh_short_C2 PF13561.6 EGB02536.1 - 1.4e-13 50.9 0.1 1.5e-13 50.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB02536.1 - 6.1e-13 48.7 0.0 7e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB02536.1 - 0.012 15.5 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 KR domain AMP-binding PF00501.28 EGB02537.1 - 4.7e-41 140.8 2.0 7e-39 133.6 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme PSII_Pbs31 PF18240.1 EGB02537.1 - 0.075 13.5 0.0 0.27 11.7 0.0 2.0 1 0 0 1 1 1 0 Photosystem II Psb31 protein DUF4121 PF13497.6 EGB02538.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Glyco_hydro_47 PF01532.20 EGB02540.1 - 1.7e-14 53.6 0.0 2.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Lig_chan PF00060.26 EGB02540.1 - 2.7e-06 27.3 0.0 4.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel DUF3377 PF11857.8 EGB02540.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cupin_8 PF13621.6 EGB02541.1 - 1.4e-05 24.9 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 Cupin-like domain BCDHK_Adom3 PF10436.9 EGB02542.1 - 4.6e-42 143.6 0.0 5.9e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGB02542.1 - 7e-10 39.4 0.0 1.3e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGB02542.1 - 7.3e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pirin_C PF05726.13 EGB02545.1 - 2.5e-16 59.9 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Pirin C-terminal cupin domain PCMT PF01135.19 EGB02546.1 - 2.5e-49 167.9 0.0 2.8e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGB02546.1 - 5.9e-07 29.4 0.1 6.6e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02546.1 - 2e-06 28.4 0.1 2.8e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB02546.1 - 0.0001 21.9 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGB02546.1 - 0.00014 21.3 0.2 0.00019 20.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGB02546.1 - 0.00077 20.1 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB02546.1 - 0.0088 15.9 0.0 0.0093 15.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGB02546.1 - 0.0094 16.0 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGB02546.1 - 0.017 14.7 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 EGB02546.1 - 0.12 13.2 0.0 0.17 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Patched PF02460.18 EGB02548.1 - 1.8e-32 112.3 9.0 3.3e-17 61.9 0.1 2.4 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 EGB02548.1 - 5.2e-10 39.4 9.3 8.4e-10 38.7 1.5 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EGB02548.1 - 0.081 11.8 23.4 0.21 10.5 10.2 3.1 2 1 0 2 2 2 0 MMPL family Trypsin_2 PF13365.6 EGB02549.1 - 5.7e-33 114.9 3.0 9.7e-33 114.2 3.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGB02549.1 - 5.4e-16 59.1 0.2 7.8e-16 58.6 0.2 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EGB02549.1 - 5.6e-11 42.6 0.3 1.8e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGB02549.1 - 8.8e-06 25.5 2.1 0.00018 21.3 0.1 3.2 3 0 0 3 3 3 1 PDZ domain Peptidase_S32 PF05579.13 EGB02549.1 - 0.00023 20.5 1.9 0.028 13.6 0.2 2.2 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Tricorn_PDZ PF14685.6 EGB02549.1 - 0.003 17.5 1.4 0.007 16.3 0.1 2.2 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 EGB02549.1 - 0.0085 14.8 1.1 0.016 13.9 0.2 1.7 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S29 PF02907.15 EGB02549.1 - 0.018 14.8 0.6 0.12 12.1 0.2 2.5 3 0 0 3 3 3 0 Hepatitis C virus NS3 protease PDZ PF00595.24 EGB02549.1 - 0.045 14.1 0.0 0.2 12.1 0.0 2.2 1 1 0 1 1 1 0 PDZ domain DOMON PF03351.17 EGB02549.1 - 0.097 12.9 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 DOMON domain PfkB PF00294.24 EGB02550.1 - 4.7e-31 108.2 2.6 8e-31 107.5 2.6 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase AhpC-TSA_2 PF13911.6 EGB02551.1 - 9e-07 29.0 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ank_5 PF13857.6 EGB02553.1 - 6.7e-06 26.3 0.2 1.5e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB02553.1 - 0.0013 19.3 0.1 0.0037 17.8 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB02553.1 - 0.0016 19.0 0.7 0.0076 16.8 0.1 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DTHCT PF08070.11 EGB02553.1 - 0.016 16.0 8.5 0.016 16.0 8.5 2.9 1 1 0 2 2 2 0 DTHCT (NUC029) region Ank_3 PF13606.6 EGB02553.1 - 0.044 14.3 0.4 1.5 9.6 0.2 2.9 2 1 0 2 2 2 0 Ankyrin repeat FAD_binding_3 PF01494.19 EGB02554.1 - 0.0062 15.8 0.1 0.0073 15.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Gly-zipper_Omp PF13488.6 EGB02556.1 - 4.8e-07 29.7 74.0 0.0005 20.0 17.5 5.3 1 1 3 4 4 4 3 Glycine zipper Gly-zipper_YMGG PF13441.6 EGB02556.1 - 1.9e-06 27.5 68.6 0.0054 16.5 5.4 5.4 2 1 2 4 4 4 3 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 EGB02556.1 - 0.005 16.6 5.1 0.005 16.6 5.1 5.7 2 1 2 4 4 4 2 Glycine-zipper domain DUF347 PF03988.12 EGB02556.1 - 1.1 9.5 36.4 0.17 12.1 9.2 5.2 1 1 3 4 4 4 0 Repeat of Unknown Function (DUF347) Romo1 PF10247.9 EGB02556.1 - 4.2 7.8 46.2 1.8 9.0 3.0 6.4 2 2 2 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 Peptidase_S28 PF05577.12 EGB02557.1 - 7.9e-44 150.1 0.2 8.7e-44 150.0 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EGB02557.1 - 1.5e-05 24.6 0.0 0.00023 20.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGB02557.1 - 0.0026 17.5 0.1 0.0053 16.4 0.1 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 EGB02557.1 - 0.0069 15.6 0.0 0.009 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) LIP PF03583.14 EGB02557.1 - 0.0081 15.5 0.1 2.7 7.3 0.0 2.0 1 1 1 2 2 2 2 Secretory lipase Hydrolase_4 PF12146.8 EGB02557.1 - 0.013 14.8 0.0 0.079 12.2 0.0 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 EGB02557.1 - 0.059 13.0 0.1 0.091 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 EGB02557.1 - 0.11 13.1 2.1 0.16 12.6 2.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family FG-GAP PF01839.23 EGB02558.1 - 8.2e-16 57.8 27.9 4.3e-07 29.9 6.3 3.6 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 EGB02558.1 - 1.1e-07 32.3 14.4 1.4e-06 28.8 9.3 2.6 2 1 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 EGB02558.1 - 1.2e-07 31.9 21.2 0.0015 18.8 0.6 4.1 3 1 0 3 3 3 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 EGB02558.1 - 0.036 13.4 3.3 0.74 9.2 0.1 2.6 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region NAPRTase PF04095.16 EGB02559.1 - 3.9e-61 206.7 0.0 5.1e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 EGB02559.1 - 2.1e-39 133.9 0.2 4.5e-39 132.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) CTP_transf_1 PF01148.20 EGB02561.1 - 6.1e-05 22.9 0.8 6.1e-05 22.9 0.8 1.5 2 0 0 2 2 2 1 Cytidylyltransferase family Snf7 PF03357.21 EGB02562.1 - 8.4e-42 142.7 13.5 1.1e-41 142.3 13.5 1.1 1 0 0 1 1 1 1 Snf7 Ax_dynein_light PF10211.9 EGB02562.1 - 0.0059 16.6 0.9 0.0059 16.6 0.9 2.2 1 1 1 2 2 2 1 Axonemal dynein light chain Cwf_Cwc_15 PF04889.12 EGB02562.1 - 0.44 10.2 7.6 0.74 9.5 7.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein E2F_CC-MB PF16421.5 EGB02562.1 - 4.2 7.8 8.7 0.93 9.9 2.0 2.4 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain FAD_binding_2 PF00890.24 EGB02563.1 - 5.5e-08 32.3 2.3 0.00037 19.7 0.2 3.4 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EGB02563.1 - 4.2e-06 26.2 1.0 3.8e-05 23.1 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB02563.1 - 9.6e-06 25.4 1.6 0.00034 20.3 0.2 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGB02563.1 - 6.7e-05 23.0 0.2 0.00037 20.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGB02563.1 - 0.00012 21.0 0.1 0.00026 19.8 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGB02563.1 - 0.00041 19.7 0.0 0.0025 17.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB02563.1 - 0.001 18.4 0.2 0.0015 17.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EGB02563.1 - 0.004 16.5 2.9 0.18 11.1 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EGB02563.1 - 0.046 12.8 1.2 0.09 11.8 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Glu_dehyd_C PF16912.5 EGB02563.1 - 0.086 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 EGB02563.1 - 0.16 12.5 0.1 0.35 11.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGB02563.1 - 0.31 11.0 1.5 9.5 6.2 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AAA_12 PF13087.6 EGB02564.1 - 1.3e-23 83.6 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGB02564.1 - 4.5e-12 46.3 0.0 5.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB02564.1 - 0.00057 19.7 1.2 0.0024 17.6 0.1 2.6 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGB02564.1 - 0.0014 18.4 0.0 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EGB02564.1 - 0.0069 16.1 0.1 0.017 14.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain KH_1 PF00013.29 EGB02566.1 - 3.6e-18 65.2 0.0 1.2e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 EGB02566.1 - 6.7e-05 22.7 0.0 0.046 13.6 0.0 2.6 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 EGB02566.1 - 0.002 17.9 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 2 KH domain SLS PF14611.6 EGB02566.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator G6PD_C PF02781.16 EGB02567.1 - 1.3e-49 169.0 0.0 1.6e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain DUF390 PF04094.14 EGB02567.1 - 0.23 9.7 26.2 0.32 9.3 26.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF1118 PF06549.12 EGB02568.1 - 0.00065 20.0 3.7 0.00065 20.0 3.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1118) GST_C_3 PF14497.6 EGB02569.1 - 2.2e-16 59.9 0.1 3.9e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB02569.1 - 2.3e-07 31.1 0.0 6.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB02569.1 - 0.00055 19.9 0.6 0.0016 18.4 0.6 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGB02569.1 - 0.0016 19.0 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB02569.1 - 0.029 14.6 0.1 0.054 13.7 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UDG PF03167.19 EGB02570.1 - 1.3e-19 70.7 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Actin PF00022.19 EGB02573.1 - 2.8e-67 227.1 0.0 1.5e-66 224.7 0.0 1.8 1 1 0 1 1 1 1 Actin Peptidase_C48 PF02902.19 EGB02574.1 - 4.2e-13 49.6 0.0 5e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain EF-hand_6 PF13405.6 EGB02575.1 - 5.8e-12 44.5 0.2 0.00016 21.3 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB02575.1 - 5e-11 42.9 0.2 7.9e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB02575.1 - 3.8e-09 35.4 0.1 0.0035 16.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.10 EGB02575.1 - 4.3e-05 23.5 0.8 0.0025 17.9 0.0 2.5 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_8 PF13833.6 EGB02575.1 - 7.6e-05 22.5 0.3 1.6 8.6 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB02575.1 - 0.00015 21.1 0.3 0.26 10.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGB02575.1 - 0.0054 17.0 0.0 0.82 10.0 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain ABC_tran PF00005.27 EGB02576.1 - 6.5e-05 23.5 0.0 9.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Radical_SAM PF04055.21 EGB02577.1 - 2.4e-12 47.5 0.0 4.1e-12 46.8 0.0 1.4 1 1 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 EGB02577.1 - 2.6e-09 37.5 0.1 4.9e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Asn_synthase PF00733.21 EGB02578.1 - 6.3e-94 315.6 1.2 7.2e-55 187.1 0.5 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGB02578.1 - 8.8e-33 112.8 0.0 1.9e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGB02578.1 - 2.4e-21 76.3 0.0 5.5e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGB02578.1 - 2.7e-05 23.8 0.0 4.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EGB02578.1 - 0.0026 16.9 0.1 0.0053 15.9 0.1 1.6 1 1 0 1 1 1 1 NAD synthase VCBS PF13517.6 EGB02580.1 - 7.3e-68 225.1 164.1 2.7e-10 40.7 8.2 11.3 2 1 10 12 12 12 11 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Laminin_G_3 PF13385.6 EGB02580.1 - 4.1e-11 43.2 0.0 4.1e-11 43.2 0.0 4.5 5 1 2 7 7 7 1 Concanavalin A-like lectin/glucanases superfamily AbfS_sensor PF18225.1 EGB02580.1 - 0.0057 16.5 0.0 67 3.5 0.0 6.0 8 0 0 8 8 8 0 Sensor histidine kinase (AbfS) sensor domain TetR_C_24 PF17932.1 EGB02580.1 - 0.029 14.6 0.3 21 5.4 0.0 4.6 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain CbiA PF01656.23 EGB02580.1 - 0.039 14.0 0.7 8.4 6.5 0.1 4.6 4 2 0 5 5 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain FG-GAP PF01839.23 EGB02580.1 - 0.15 12.2 106.9 0.2 11.8 4.5 12.4 12 0 0 12 12 12 0 FG-GAP repeat Dockerin_1 PF00404.18 EGB02580.1 - 0.37 11.0 78.4 1.4 9.1 0.1 11.1 8 4 1 9 9 9 0 Dockerin type I domain LcrR PF09621.10 EGB02580.1 - 0.83 9.1 2.4 69 2.9 0.0 4.8 5 1 1 6 6 6 0 Type III secretion system regulator (LcrR) Pollen_allerg_1 PF01357.21 EGB02580.1 - 1.7 8.7 15.1 11 6.1 0.1 7.5 7 2 1 9 9 9 0 Pollen allergen Es2 PF09751.9 EGB02581.1 - 2.4e-22 80.3 0.0 2.6e-12 47.2 0.0 2.2 1 1 1 2 2 2 2 Nuclear protein Es2 Laminin_G_3 PF13385.6 EGB02582.1 - 8e-93 308.5 61.0 8.9e-23 81.1 2.7 7.2 5 2 2 8 8 8 5 Concanavalin A-like lectin/glucanases superfamily VCBS PF13517.6 EGB02582.1 - 3.2e-22 78.9 67.9 5.9e-09 36.4 10.4 8.7 7 3 4 11 11 11 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Pentaxin PF00354.17 EGB02582.1 - 4.3e-18 65.7 0.7 0.00068 19.4 0.2 5.4 4 1 1 5 5 5 5 Pentaxin family Laminin_G_2 PF02210.24 EGB02582.1 - 8.5e-07 29.6 4.8 0.12 13.0 0.0 5.2 5 0 0 5 5 5 2 Laminin G domain Terminase_5 PF06056.12 EGB02582.1 - 0.0027 17.6 0.0 0.095 12.6 0.0 3.0 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) Chlorovi_GP_rpt PF06598.11 EGB02582.1 - 0.0072 16.4 0.0 1.4e+02 2.7 0.0 5.2 5 0 0 5 5 5 0 Chlorovirus glycoprotein repeat Glyco_hydro_16 PF00722.21 EGB02582.1 - 0.044 13.2 12.3 2.1 7.8 0.1 4.5 5 0 0 5 5 5 0 Glycosyl hydrolases family 16 Phage_terminase PF10668.9 EGB02582.1 - 0.048 13.7 0.1 80 3.4 0.0 4.1 5 0 0 5 5 5 0 Phage terminase small subunit Dockerin_1 PF00404.18 EGB02582.1 - 0.47 10.7 39.4 8 6.7 0.3 6.8 4 2 1 5 5 5 0 Dockerin type I domain DUF5605 PF18310.1 EGB02582.1 - 0.81 9.6 3.9 80 3.2 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5605) DUF702 PF05142.12 EGB02583.1 - 0.12 12.8 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Caskin-Pro-rich PF16907.5 EGB02583.1 - 0.83 10.2 5.8 1.7 9.2 5.8 1.6 1 0 0 1 1 1 0 Proline rich region of Caskin proteins HemolysinCabind PF00353.19 EGB02584.1 - 2.7 8.1 79.0 0.78 9.8 1.6 12.4 10 1 2 12 12 12 0 RTX calcium-binding nonapeptide repeat (4 copies) Peptidase_S9 PF00326.21 EGB02585.1 - 7.1e-06 25.6 0.1 1.7e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGB02585.1 - 0.00022 20.6 1.0 0.24 10.6 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EGB02585.1 - 0.00062 19.5 0.0 0.00067 19.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EGB02585.1 - 0.0045 16.7 0.0 0.0071 16.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGB02585.1 - 0.061 12.9 0.0 0.084 12.4 0.0 1.2 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 EGB02585.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 EGB02585.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family STELLO PF03385.17 EGB02587.1 - 3e-15 55.9 0.0 3.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases SURNod19 PF07712.12 EGB02589.1 - 2e-07 30.1 0.2 0.0041 15.9 0.1 3.1 2 1 0 2 2 2 2 Stress up-regulated Nod 19 AhpC-TSA_2 PF13911.6 EGB02590.1 - 3.9e-15 55.9 0.0 8.7e-15 54.8 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 EGB02590.1 - 5e-05 23.0 0.0 7.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGB02590.1 - 9.9e-05 22.3 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF4726 PF15855.5 EGB02590.1 - 0.067 13.4 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) GT87 PF09594.10 EGB02591.1 - 0.0015 18.3 4.4 0.0029 17.4 4.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 87 Sel1 PF08238.12 EGB02592.1 - 1.2e-39 133.9 24.2 6.9e-09 36.1 0.2 7.7 7 2 0 7 7 7 7 Sel1 repeat TPR_12 PF13424.6 EGB02592.1 - 0.0007 19.8 14.4 0.043 14.1 0.8 5.2 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02592.1 - 0.0013 18.5 12.5 0.12 12.3 0.6 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02592.1 - 0.0015 18.2 0.7 0.058 13.2 0.4 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGB02592.1 - 0.012 15.6 0.5 2.3 8.3 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF410 PF04190.13 EGB02592.1 - 0.021 14.7 0.3 5.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF410) DUF977 PF06163.11 EGB02592.1 - 0.037 14.0 1.1 1.2 9.1 0.1 3.0 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF977) TPR_8 PF13181.6 EGB02592.1 - 0.059 13.6 4.2 9.2 6.8 0.2 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02592.1 - 0.18 12.0 25.6 0.25 11.6 1.4 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02592.1 - 0.3 11.2 8.6 3 8.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02592.1 - 0.36 11.5 20.7 0.36 11.5 0.5 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB02592.1 - 0.78 10.2 3.0 37 4.8 0.0 3.7 4 2 1 5 5 5 0 B12 binding domain Redoxin PF08534.10 EGB02593.1 - 0.031 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 EGB02593.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family EamA PF00892.20 EGB02594.1 - 6.9e-14 52.2 13.9 3.6e-09 36.9 3.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family DUF543 PF04418.12 EGB02594.1 - 0.59 10.2 6.1 3 7.9 6.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Nucleotid_trans PF03407.16 EGB02595.1 - 2.6e-26 92.9 0.2 3.4e-26 92.6 0.2 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase MutS_V PF00488.21 EGB02596.1 - 4.8e-15 56.1 0.0 7.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V SET PF00856.28 EGB02596.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 SET domain DEAD PF00270.29 EGB02597.1 - 6.4e-44 149.8 0.0 1e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB02597.1 - 7.6e-18 64.9 0.0 5.6e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB02597.1 - 2.2e-06 27.8 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGB02597.1 - 0.00016 21.0 0.0 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 EGB02597.1 - 0.19 11.0 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain EII-Sor PF03609.14 EGB02597.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 PTS system sorbose-specific iic component ADSL_C PF10397.9 EGB02602.1 - 0.049 14.2 0.1 0.049 14.2 0.1 2.3 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus XhlA PF10779.9 EGB02602.1 - 2.8 8.2 4.8 6.9 7.0 4.8 1.7 1 0 0 1 1 1 0 Haemolysin XhlA PT PF04886.12 EGB02604.1 - 0.0018 17.8 19.8 0.0018 17.8 19.8 3.3 3 1 0 3 3 3 2 PT repeat TENA_THI-4 PF03070.16 EGB02605.1 - 4.5e-34 118.1 0.0 5.1e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family CN_hydrolase PF00795.22 EGB02606.1 - 1.2e-47 162.4 0.1 1.6e-47 162.0 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pro_Al_protease PF02983.14 EGB02606.1 - 2 8.5 8.5 0.15 12.2 0.5 3.0 3 0 0 3 3 3 0 Alpha-lytic protease prodomain Methyltransf_3 PF01596.17 EGB02607.1 - 7e-34 116.9 0.0 7.8e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGB02607.1 - 3.4e-07 31.2 0.0 5.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.19 EGB02608.1 - 2e-05 24.0 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB02608.1 - 8.8e-05 21.9 0.0 9.1e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB02608.1 - 0.00039 20.6 0.0 0.00059 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGB02608.1 - 0.022 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGB02608.1 - 0.057 13.4 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGB02608.1 - 0.14 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein His_Phos_1 PF00300.22 EGB02609.1 - 2.9e-16 59.7 4.4 5e-15 55.7 4.4 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Reprolysin_5 PF13688.6 EGB02609.1 - 0.00074 19.7 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EGB02609.1 - 0.047 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Cofac_haem_bdg PF04187.13 EGB02610.1 - 2.9e-06 27.5 0.0 4.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN YpmT PF17431.2 EGB02610.1 - 0.075 13.1 0.6 7.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized YmpT-like PSK_trans_fac PF07704.11 EGB02611.1 - 0.069 13.9 1.2 0.069 13.9 1.2 1.6 2 0 0 2 2 2 0 Rv0623-like transcription factor 2OG-FeII_Oxy_3 PF13640.6 EGB02612.1 - 1.2e-05 26.1 0.0 2.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSF_DNA-bind PF00447.17 EGB02613.1 - 8.9e-25 87.1 0.0 1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Ank_2 PF12796.7 EGB02614.1 - 4e-28 97.8 1.4 2.8e-18 66.3 0.4 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB02614.1 - 1e-22 77.7 2.1 3.8e-05 23.7 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EGB02614.1 - 2.1e-21 75.3 8.9 1.5e-06 28.3 0.4 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EGB02614.1 - 6.3e-20 71.3 3.6 4.4e-08 33.5 0.0 4.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB02614.1 - 1.6e-17 63.3 3.6 3.1e-05 24.2 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) ketoacyl-synt PF00109.26 EGB02616.1 - 3.8e-17 62.7 1.6 4.2e-17 62.6 1.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain N6-adenineMlase PF10237.9 EGB02617.1 - 7.5e-12 45.3 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase OB_NTP_bind PF07717.16 EGB02617.1 - 2.6e-09 37.3 0.0 4.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGB02617.1 - 0.13 12.6 0.1 4 7.8 0.0 2.5 2 0 0 2 2 2 0 Helicase associated domain (HA2) His_Phos_1 PF00300.22 EGB02618.1 - 0.0053 16.5 0.0 0.43 10.2 0.2 2.8 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) malic PF00390.19 EGB02619.1 - 5.7e-70 234.8 0.0 7.4e-70 234.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 EGB02619.1 - 4e-23 82.0 0.1 5.7e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain HD_assoc PF13286.6 EGB02619.1 - 0.082 13.5 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphohydrolase-associated domain DUF4603 PF15376.6 EGB02621.1 - 0.027 11.9 0.1 0.032 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF4346 PF14251.6 EGB02623.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) DUF945 PF06097.11 EGB02624.1 - 0.47 9.5 3.9 0.14 11.3 0.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF945) SecA_SW PF07516.13 EGB02624.1 - 0.89 9.6 5.7 0.73 9.9 0.1 2.5 2 1 0 2 2 2 0 SecA Wing and Scaffold domain DUF445 PF04286.12 EGB02624.1 - 8.5 6.1 10.9 11 5.6 5.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF445) HAD_2 PF13419.6 EGB02625.1 - 4.2e-24 85.6 0.0 4.9e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB02625.1 - 1.4e-15 58.2 0.1 1.8e-14 54.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB02625.1 - 1.1e-06 29.2 0.0 1.6e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB02625.1 - 0.0009 19.3 0.3 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Par3_HAL_N_term PF12053.8 EGB02626.1 - 0.00053 20.1 0.2 0.00068 19.8 0.2 1.1 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Cytokin_check_N PF10407.9 EGB02626.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus EMG1 PF03587.14 EGB02628.1 - 9.8e-70 234.2 0.0 1.2e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Methyltransf_11 PF08241.12 EGB02629.1 - 2.5e-24 85.7 0.0 3.5e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02629.1 - 6.5e-21 74.9 0.0 9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB02629.1 - 2e-20 73.3 0.0 2.6e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB02629.1 - 1.1e-16 61.4 0.0 1.7e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02629.1 - 8.7e-14 51.6 0.0 1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB02629.1 - 3.8e-11 42.8 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EGB02629.1 - 7.4e-07 29.0 0.0 1.7e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 EGB02629.1 - 0.0002 20.8 0.0 0.00027 20.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGB02629.1 - 0.0002 20.9 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain AdoMet_MTase PF07757.13 EGB02629.1 - 0.00032 21.0 0.0 0.00055 20.2 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_24 PF13578.6 EGB02629.1 - 0.0023 18.9 0.0 0.0034 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGB02629.1 - 0.0052 16.2 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 EGB02629.1 - 0.028 14.3 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase PrmA PF06325.13 EGB02629.1 - 0.071 12.5 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 EGB02629.1 - 0.071 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EGB02629.1 - 0.077 13.0 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EGB02629.1 - 0.097 12.8 0.0 0.16 12.0 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ephrin_rec_like PF07699.13 EGB02630.1 - 1e-18 66.8 234.4 0.00049 19.8 4.9 24.5 17 5 6 25 25 25 18 Putative ephrin-receptor like Invasin_D3 PF09134.10 EGB02630.1 - 1.1 9.6 8.5 0.16 12.3 1.6 3.2 3 1 1 4 4 4 0 Invasin, domain 3 Big_2 PF02368.18 EGB02630.1 - 1.5 8.8 7.3 3.1 7.7 7.3 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) NifU PF01106.17 EGB02630.1 - 2.3 8.4 5.9 52 4.1 0.0 4.0 2 1 0 2 2 2 0 NifU-like domain Armet PF10208.9 EGB02631.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Spermine_synth PF01564.17 EGB02632.1 - 7.9e-25 87.4 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain EF-hand_5 PF13202.6 EGB02632.1 - 9e-06 25.0 0.1 2.7e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 EF hand Spermine_synt_N PF17284.2 EGB02632.1 - 5.3e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain EF-hand_6 PF13405.6 EGB02632.1 - 6.6e-05 22.5 0.0 0.00021 21.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EGB02632.1 - 0.0002 20.7 0.3 0.00063 19.1 0.0 2.0 2 0 0 2 2 2 1 EF hand Ion_trans_2 PF07885.16 EGB02632.1 - 0.0005 20.0 6.6 0.0011 18.9 6.6 1.5 1 0 0 1 1 1 1 Ion channel EF-hand_7 PF13499.6 EGB02632.1 - 0.00077 19.9 0.1 0.0024 18.3 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair Methyltransf_24 PF13578.6 EGB02632.1 - 0.0095 16.9 0.7 0.83 10.7 0.1 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02632.1 - 0.13 13.0 0.2 0.38 11.5 0.2 1.8 1 0 0 1 1 1 0 Methyltransferase domain Arm PF00514.23 EGB02633.1 - 3.5e-30 103.1 14.7 3.8e-06 26.7 0.1 8.6 8 1 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB02633.1 - 2e-14 53.7 2.9 0.00052 20.3 0.2 5.1 3 2 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EGB02633.1 - 4.6e-11 43.0 7.9 0.041 14.4 0.1 6.5 5 1 1 6 6 6 5 HEAT-like repeat HEAT PF02985.22 EGB02633.1 - 2.1e-09 36.8 5.8 0.068 13.5 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat Proteasom_PSMB PF10508.9 EGB02633.1 - 9.5e-06 24.4 0.0 0.00039 19.0 0.0 2.3 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 EGB02633.1 - 0.011 14.3 0.0 0.021 13.4 0.0 1.6 1 1 0 1 1 1 0 Adaptin N terminal region Cnd1 PF12717.7 EGB02633.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 EGB02634.1 - 7.7e-09 35.3 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02634.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Vps35 PF03635.17 EGB02635.1 - 1.5e-86 291.6 0.0 1.6e-86 291.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 HD_4 PF13328.6 EGB02636.1 - 1.4e-48 164.6 0.4 1.7e-48 164.3 0.4 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.22 EGB02636.1 - 2.1e-08 34.4 0.3 7.9e-08 32.6 0.2 2.0 2 0 0 2 2 2 1 HD domain DNA_pol3_gamma3 PF12169.8 EGB02636.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Phasin_2 PF09361.10 EGB02636.1 - 0.12 12.7 0.1 0.69 10.2 0.0 2.1 2 0 0 2 2 2 0 Phasin protein DUF4079 PF13301.6 EGB02637.1 - 0.13 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) WW PF00397.26 EGB02638.1 - 6e-08 32.6 0.3 1.9e-07 31.0 0.3 1.9 1 0 0 1 1 1 1 WW domain APG6 PF04111.12 EGB02640.1 - 1.8e-13 50.9 0.1 1.8e-13 50.8 0.1 1.0 1 0 0 1 1 1 1 Apg6 BARA domain Myosin_head PF00063.21 EGB02641.1 - 3.8e-159 531.1 0.0 1.6e-124 416.6 0.0 2.3 1 1 1 2 2 2 2 Myosin head (motor domain) Myosin_N PF02736.19 EGB02641.1 - 0.0013 18.6 1.2 0.0065 16.3 0.7 2.2 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_6 PF12774.7 EGB02641.1 - 0.0047 15.9 1.4 1.6 7.6 0.1 2.2 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 EGB02641.1 - 0.054 13.9 0.1 0.054 13.9 0.1 3.6 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EGB02641.1 - 0.093 13.0 0.2 0.44 10.8 0.2 2.1 1 0 0 1 1 1 0 AAA domain Cytochrom_B561 PF03188.16 EGB02642.1 - 4.1e-08 33.5 0.7 7.9e-08 32.5 0.7 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EGB02642.1 - 0.00091 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Polyketide_cyc PF03364.20 EGB02644.1 - 1.3e-15 57.7 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EGB02644.1 - 5.9e-09 36.3 0.1 7.2e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 EGB02644.1 - 0.01 15.6 0.0 0.081 12.7 0.0 2.1 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) PhyH PF05721.13 EGB02645.1 - 1.9e-30 106.7 0.0 2.3e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) KAR9 PF08580.10 EGB02646.1 - 4 5.9 6.4 4.3 5.8 6.4 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CH PF00307.31 EGB02647.1 - 3.7e-15 56.1 0.0 3.9e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EGB02647.1 - 0.023 14.9 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 CDC24 Calponin Img2 PF05046.14 EGB02648.1 - 7e-12 45.5 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) RdRP PF05183.12 EGB02649.1 - 6.9e-33 114.1 0.0 9.8e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sulfatase PF00884.23 EGB02649.1 - 3.1e-31 108.9 0.0 5.5e-31 108.1 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB02649.1 - 3.7e-05 23.5 0.0 0.068 12.7 0.0 2.6 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_transf_34 PF05637.12 EGB02649.1 - 0.00063 19.5 0.1 0.0016 18.2 0.1 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Scramblase PF03803.15 EGB02650.1 - 3.3e-09 36.4 0.0 1.7e-05 24.2 0.0 4.0 3 1 0 3 3 3 3 Scramblase PA PF02225.22 EGB02650.1 - 1.8e-06 27.8 0.0 5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 PA domain His_Phos_1 PF00300.22 EGB02652.1 - 2.5e-30 105.6 0.1 2.9e-22 79.3 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Sulfatase PF00884.23 EGB02654.1 - 4.7e-33 114.9 0.0 5.3e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Sulfatase HMG_box PF00505.19 EGB02655.1 - 0.13 12.6 8.7 12 6.4 3.0 3.6 2 1 1 3 3 3 0 HMG (high mobility group) box RGS12_us1 PF16613.5 EGB02655.1 - 0.19 12.0 0.7 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Unstructured region of RGS12 DnaJ PF00226.31 EGB02656.1 - 3.4e-13 49.5 0.2 6.2e-13 48.7 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 EGB02656.1 - 0.00014 22.3 3.2 0.00014 22.3 3.2 1.8 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02656.1 - 0.00062 20.4 4.5 0.00062 20.4 4.5 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02656.1 - 0.00099 19.1 0.4 0.46 10.8 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02656.1 - 0.0045 16.7 2.1 0.46 10.4 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02656.1 - 0.011 16.5 10.9 0.025 15.4 0.5 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat SIMPL PF04402.14 EGB02656.1 - 0.014 15.9 3.0 0.015 15.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) ImpA_N PF06812.12 EGB02656.1 - 0.038 14.1 0.5 0.5 10.5 0.1 2.0 1 1 1 2 2 2 0 ImpA, N-terminal, type VI secretion system Sialidase PF02973.16 EGB02656.1 - 0.054 13.0 0.0 0.082 12.4 0.0 1.3 1 1 0 1 1 1 0 Sialidase, N-terminal domain TPR_2 PF07719.17 EGB02656.1 - 0.057 13.6 7.1 0.65 10.3 0.4 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB02656.1 - 0.058 13.5 0.1 0.61 10.2 0.1 2.6 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EGB02656.1 - 2.4 8.4 7.4 6.2 7.1 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat ADH_N PF08240.12 EGB02657.1 - 4.1e-21 74.9 9.2 5.6e-21 74.5 9.2 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGB02657.1 - 0.00011 22.2 0.3 0.00021 21.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 EGB02657.1 - 0.0034 16.8 0.3 0.0065 15.9 0.3 1.4 1 0 0 1 1 1 1 ThiF family TOBE_2 PF08402.10 EGB02657.1 - 0.01 16.0 0.2 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 TOBE domain 2-Hacid_dh_C PF02826.19 EGB02657.1 - 0.011 15.1 2.4 0.022 14.1 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phos_pyr_kin PF08543.12 EGB02658.1 - 3.7e-13 49.4 0.0 4.9e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGB02658.1 - 7.2e-06 25.5 1.2 4.5e-05 22.9 0.2 2.4 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 EGB02658.1 - 0.01 15.3 0.0 0.15 11.5 0.0 2.5 3 0 0 3 3 3 0 Carbohydrate kinase NMT1 PF09084.11 EGB02659.1 - 1.2e-44 152.9 0.0 1.4e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EGB02659.1 - 0.00031 20.4 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 EGB02659.1 - 0.011 15.4 0.0 0.035 13.8 0.0 1.8 2 1 0 2 2 2 0 NMT1-like family Fibrinogen_aC PF12160.8 EGB02659.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha C domain Steroid_dh PF02544.16 EGB02660.1 - 0.003 17.6 0.1 0.0042 17.1 0.1 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Na_H_Exchanger PF00999.21 EGB02661.1 - 2.8e-19 69.2 27.0 2.6e-15 56.1 23.9 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family HSF_DNA-bind PF00447.17 EGB02661.1 - 1.8e-09 38.1 0.0 3.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Phage_lysis PF03245.13 EGB02661.1 - 0.17 12.0 0.7 12 6.0 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein MFS_1 PF07690.16 EGB02662.1 - 6.5e-16 58.2 20.1 1.1e-15 57.4 20.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF554 PF04474.12 EGB02662.1 - 0.001 18.6 0.9 0.003 17.1 0.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF554) Sugar_tr PF00083.24 EGB02662.1 - 0.076 11.9 8.9 0.3 9.9 4.0 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter HEAT PF02985.22 EGB02663.1 - 2.4e-09 36.7 2.1 0.26 11.6 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EGB02663.1 - 2.7e-08 34.1 10.4 3.1e-05 24.3 0.3 3.0 2 1 1 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EGB02663.1 - 4.2e-05 24.1 0.2 0.0075 16.8 0.1 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGB02663.1 - 0.0042 17.6 8.7 2.3 8.8 0.0 4.1 2 2 2 4 4 4 3 HEAT-like repeat Cnd1 PF12717.7 EGB02663.1 - 0.0072 16.4 0.2 0.35 10.9 0.2 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Chloroplast_duf PF14476.6 EGB02663.1 - 0.084 11.8 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Petal formation-expressed WD40 PF00400.32 EGB02664.1 - 0.098 13.6 0.0 0.55 11.2 0.0 2.4 1 0 0 1 1 1 0 WD domain, G-beta repeat Abhydrolase_2 PF02230.16 EGB02665.1 - 1.4e-15 57.7 0.0 1.5e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGB02665.1 - 9.8e-07 28.6 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EGB02665.1 - 0.00029 20.5 0.0 0.00038 20.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EGB02665.1 - 0.011 15.0 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGB02665.1 - 0.021 15.0 0.1 0.043 13.9 0.1 1.6 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 EGB02665.1 - 0.076 12.6 0.1 0.25 11.0 0.1 1.7 1 1 1 2 2 2 0 Putative esterase DUF2957 PF11170.8 EGB02665.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2957) DUF1610 PF07754.11 EGB02665.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) BAAT_C PF08840.11 EGB02665.1 - 0.18 11.7 0.1 1.9 8.3 0.1 2.0 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aa_trans PF01490.18 EGB02667.1 - 8.4e-27 93.9 7.7 1e-26 93.6 7.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGB02667.1 - 5.2e-09 35.6 10.0 6.7e-09 35.3 10.0 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 EGB02667.1 - 0.014 14.2 0.7 0.014 14.2 0.7 1.7 2 0 0 2 2 2 0 Spore germination protein Chloroa_b-bind PF00504.21 EGB02668.1 - 5.9e-23 82.2 0.0 7.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ABM PF03992.16 EGB02670.1 - 5.1e-09 36.1 0.0 6.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase VCBS PF13517.6 EGB02671.1 - 1.1e-66 221.3 126.7 5.2e-11 43.0 4.9 13.0 6 1 6 12 12 12 11 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella REJ PF02010.15 EGB02671.1 - 2.4e-28 99.1 0.0 3.6e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 REJ domain AbfS_sensor PF18225.1 EGB02671.1 - 0.013 15.4 0.0 1.5e+02 2.4 0.0 5.9 8 0 0 8 8 8 0 Sensor histidine kinase (AbfS) sensor domain He_PIG PF05345.12 EGB02671.1 - 0.042 14.0 4.5 0.082 13.1 0.3 3.1 2 0 0 2 2 2 0 Putative Ig domain HalOD2 PF18547.1 EGB02671.1 - 0.13 12.1 1.0 0.61 10.0 1.0 2.2 1 0 0 1 1 1 0 Halobacterial output domain 2 HTH_31 PF13560.6 EGB02671.1 - 0.55 10.6 17.3 5.1 7.5 0.0 9.1 12 0 0 12 12 12 0 Helix-turn-helix domain ADK PF00406.22 EGB02672.1 - 5.2e-44 150.0 0.0 6.4e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGB02672.1 - 1.5e-30 106.4 0.0 2.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB02672.1 - 5.3e-07 29.9 0.0 7.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB02672.1 - 1.2e-06 29.1 0.0 1.7e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGB02672.1 - 0.0078 15.9 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 EGB02672.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Lipase_GDSL_2 PF13472.6 EGB02673.1 - 0.00043 20.7 1.1 0.001 19.5 0.3 2.0 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family S-AdoMet_synt_N PF00438.20 EGB02674.1 - 2.5e-38 130.7 0.2 3.5e-38 130.3 0.2 1.2 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EGB02674.1 - 3.4e-26 91.9 0.0 8.2e-26 90.6 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain COMM_domain PF07258.14 EGB02675.1 - 4.2e-14 52.4 0.1 7.9e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 COMM domain Acyl_transf_3 PF01757.22 EGB02675.1 - 2.1e-11 43.5 18.5 3.4e-11 42.8 18.5 1.2 1 0 0 1 1 1 1 Acyltransferase family dCache_1 PF02743.18 EGB02675.1 - 1.3e-05 25.1 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Cache domain Ribosomal_60s PF00428.19 EGB02676.1 - 3e-17 63.0 7.6 3.5e-17 62.8 7.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2967 PF11179.8 EGB02676.1 - 7.7 4.5 8.2 7.9 4.4 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Myotub-related PF06602.14 EGB02677.1 - 6.6e-17 61.5 0.0 8e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GLF PF03275.13 EGB02679.1 - 3.4e-71 239.2 0.0 4.3e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 EGB02679.1 - 1.6e-07 31.4 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGB02679.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TIP49_C PF17856.1 EGB02680.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 TIP49 AAA-lid domain Cnd2 PF05786.14 EGB02680.1 - 5.2 5.6 6.4 7.3 5.1 6.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 NOA36 PF06524.12 EGB02680.1 - 8.6 5.6 11.7 14 4.9 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein Tmemb_cc2 PF10267.9 EGB02681.1 - 0.12 11.5 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PIP5K PF01504.18 EGB02682.1 - 4.7e-16 58.8 0.0 7.4e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SnoaL_2 PF12680.7 EGB02682.1 - 0.059 14.0 0.5 0.21 12.3 0.5 2.0 1 0 0 1 1 1 0 SnoaL-like domain PDZ_6 PF17820.1 EGB02683.1 - 0.025 14.4 0.6 0.066 13.1 0.0 2.1 2 1 0 2 2 2 0 PDZ domain PDZ_2 PF13180.6 EGB02683.1 - 0.1 12.9 0.1 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 PDZ domain Solute_trans_a PF03619.16 EGB02684.1 - 4.2e-21 75.7 1.7 5.2e-21 75.4 1.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MerR-DNA-bind PF09278.11 EGB02684.1 - 0.072 13.6 0.9 55 4.4 0.2 3.4 3 0 0 3 3 3 0 MerR, DNA binding Apolipoprotein PF01442.18 EGB02684.1 - 0.88 9.4 13.3 2.3 8.0 13.3 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Metallophos PF00149.28 EGB02685.1 - 4.4e-10 40.4 0.0 6.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HMA PF00403.26 EGB02685.1 - 0.0004 20.8 0.2 0.0004 20.8 0.2 3.6 4 0 0 4 4 4 1 Heavy-metal-associated domain GXGXG PF01493.19 EGB02685.1 - 0.064 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 GXGXG motif Pyridoxal_deC PF00282.19 EGB02686.1 - 0.00025 19.9 0.0 0.00032 19.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.19 EGB02687.1 - 4.5e-43 147.4 0.0 5.1e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Carb_kinase PF01256.17 EGB02688.1 - 0.013 14.9 3.6 0.013 14.9 3.6 2.3 2 0 0 2 2 2 0 Carbohydrate kinase CSD PF00313.22 EGB02690.1 - 3.5e-12 46.0 0.1 5.9e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCCH_4 PF18044.1 EGB02690.1 - 4.7e-06 26.3 2.9 1.1e-05 25.0 2.9 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGB02690.1 - 1e-05 25.4 5.7 2.3e-05 24.3 5.7 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EGB02690.1 - 2.3e-05 24.2 2.2 6e-05 22.8 2.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) OB_RNB PF08206.11 EGB02690.1 - 0.00023 20.8 0.1 0.00077 19.1 0.1 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain Torus PF16131.5 EGB02690.1 - 0.021 15.5 1.8 0.021 15.5 1.8 1.7 2 0 0 2 2 2 0 Torus domain 2OG-FeII_Oxy_3 PF13640.6 EGB02691.1 - 0.00019 22.2 0.0 0.00032 21.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB02691.1 - 0.00051 20.6 0.0 0.00099 19.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF494 PF04361.13 EGB02692.1 - 0.086 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF494) TIG PF01833.24 EGB02693.1 - 3.4e-08 33.4 0.0 0.0018 18.3 0.0 4.2 4 1 0 4 4 4 3 IPT/TIG domain RIIa PF02197.17 EGB02694.1 - 1.6e-07 30.9 0.0 3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF5582 PF17819.1 EGB02694.1 - 0.043 14.3 0.0 0.064 13.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DUF5586 PF17824.1 EGB02694.1 - 0.22 10.6 0.0 0.42 9.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5586) EF-hand_6 PF13405.6 EGB02695.1 - 2.8e-05 23.7 0.0 0.013 15.3 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 EGB02695.1 - 0.0051 16.3 0.2 0.024 14.1 0.0 2.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EGB02695.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair TFCD_C PF12612.8 EGB02697.1 - 0.0079 16.0 0.0 0.031 14.1 0.0 2.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HMG_CoA_synt_N PF01154.17 EGB02698.1 - 5.9e-27 94.6 0.2 6.4e-27 94.5 0.2 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal FragX_IP PF05994.11 EGB02700.1 - 5.4e-19 67.8 0.0 8.4e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 EGB02700.1 - 0.0066 15.8 0.2 0.0091 15.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Vps26 PF03643.15 EGB02701.1 - 3.9e-100 334.4 0.6 4.7e-100 334.1 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGB02701.1 - 0.15 12.1 0.2 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Sel1 PF08238.12 EGB02702.1 - 1.6e-30 104.9 24.5 3.1e-07 30.8 0.5 7.4 7 1 0 7 7 7 6 Sel1 repeat EF-hand_like PF09279.11 EGB02702.1 - 0.00019 21.8 0.2 0.13 12.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like CZB PF13682.6 EGB02702.1 - 0.026 15.0 0.1 2.4 8.7 0.0 3.1 2 1 0 2 2 2 0 Chemoreceptor zinc-binding domain AAA_lid_10 PF17872.1 EGB02702.1 - 0.032 14.3 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA lid domain DUF3228 PF11539.8 EGB02702.1 - 0.079 12.5 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) DUF977 PF06163.11 EGB02702.1 - 0.12 12.3 1.0 7 6.6 0.0 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF977) B12-binding_2 PF02607.17 EGB02702.1 - 2.6 8.5 10.2 19 5.8 1.4 3.6 2 2 1 3 3 3 0 B12 binding domain Phage_GP20 PF06810.11 EGB02703.1 - 0.029 14.2 0.5 0.26 11.1 0.0 2.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 GIT_CC PF16559.5 EGB02703.1 - 0.048 13.5 0.2 0.14 12.0 0.2 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor COG2 PF06148.11 EGB02703.1 - 0.049 13.7 3.4 0.82 9.8 0.0 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 EGB02703.1 - 0.093 12.8 4.5 2 8.4 0.3 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 EGB02703.1 - 0.12 12.4 7.0 0.53 10.4 0.7 3.8 4 1 0 4 4 4 0 TolA binding protein trimerisation YabA PF06156.13 EGB02703.1 - 0.16 12.6 0.9 0.55 10.9 0.3 2.1 2 1 0 2 2 2 0 Initiation control protein YabA SYCE1 PF15233.6 EGB02703.1 - 0.19 11.8 1.9 9.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 ZapB PF06005.12 EGB02703.1 - 0.19 12.2 9.5 11 6.5 1.9 4.9 4 3 0 4 4 4 0 Cell division protein ZapB Spc7 PF08317.11 EGB02703.1 - 0.25 10.2 12.2 0.77 8.6 0.5 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein CAP_N PF01213.19 EGB02703.1 - 0.58 9.6 7.2 1 8.7 7.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal KASH_CCD PF14662.6 EGB02703.1 - 0.63 9.8 4.7 2.2 8.1 0.4 2.7 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 EGB02703.1 - 0.87 9.9 5.1 51 4.2 0.1 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper RRP36 PF06102.12 EGB02703.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.5 3 0 0 3 3 3 0 rRNA biogenesis protein RRP36 PRKG1_interact PF15898.5 EGB02703.1 - 1.4 9.8 6.4 13 6.8 0.1 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain HAUS-augmin3 PF14932.6 EGB02703.1 - 1.8 8.1 11.2 0.99 8.9 1.7 2.6 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 EGB02703.1 - 3.8 6.7 17.9 0.43 9.8 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 EGB02703.1 - 7.4 6.7 27.8 0.036 14.3 3.0 3.8 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EGB02703.1 - 8.3 5.7 29.3 24 4.2 3.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ubiquitin PF00240.23 EGB02704.1 - 1.5e-27 95.1 0.2 1.6e-27 95.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB02704.1 - 1.3e-11 44.1 0.2 1.4e-11 44.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB02704.1 - 2.1e-06 28.1 0.1 1.1e-05 25.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB02704.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGB02704.1 - 0.0031 17.9 0.0 0.0037 17.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB02704.1 - 0.0033 17.5 0.0 0.0066 16.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGB02704.1 - 0.022 15.3 0.0 0.026 15.1 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DNA_pol_B_thumb PF14791.6 EGB02706.1 - 2.4e-09 37.2 0.4 5e-05 23.4 0.1 2.6 2 0 0 2 2 2 2 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EGB02706.1 - 0.00091 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm TP_methylase PF00590.20 EGB02707.1 - 1.7e-07 31.4 0.3 1.7e-07 31.4 0.3 1.5 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Arm PF00514.23 EGB02709.1 - 4.4e-34 115.5 19.2 5.8e-08 32.5 0.1 7.1 6 2 0 6 6 6 5 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EGB02709.1 - 9.8e-05 21.9 0.3 0.026 14.0 0.3 3.4 1 1 2 3 3 3 2 Armadillo-like HEAT_EZ PF13513.6 EGB02709.1 - 0.18 12.3 0.3 0.18 12.3 0.3 4.6 2 2 3 5 5 5 0 HEAT-like repeat Cyclin_N PF00134.23 EGB02711.1 - 8e-05 22.4 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGB02711.1 - 0.035 14.5 0.1 0.13 12.6 0.1 1.8 1 1 0 1 1 1 0 Cyclin RCC1 PF00415.18 EGB02712.1 - 7.3e-37 125.8 13.6 2.5e-12 47.2 0.1 5.8 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB02712.1 - 6.3e-30 102.3 26.1 1.1e-09 37.8 0.2 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 EGB02712.1 - 6.7 7.2 6.6 7.4 7.0 0.1 3.3 4 0 0 4 4 4 0 Kelch motif Aldo_ket_red PF00248.21 EGB02713.1 - 1.3e-25 90.3 0.0 4.2e-23 82.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L12 PF00542.19 EGB02714.1 - 1.2e-28 99.3 9.4 1.3e-27 96.0 6.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGB02714.1 - 1.2e-17 63.3 5.8 1.2e-17 63.3 5.8 2.8 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DAHP_snth_FXD PF18152.1 EGB02714.1 - 0.13 12.2 1.8 0.26 11.1 0.2 2.3 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain S-AdoMet_synt_C PF02773.16 EGB02715.1 - 4.8e-58 195.0 0.0 9.2e-58 194.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain Gelsolin PF00626.22 EGB02716.1 - 4.1e-20 71.5 0.0 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Gelsolin repeat Arylsulfotrans PF05935.11 EGB02717.1 - 1.7e-11 43.7 0.4 3.4e-11 42.7 0.4 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DUF3698 PF12479.8 EGB02718.1 - 0.2 12.2 0.1 0.29 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) PHD PF00628.29 EGB02719.1 - 0.043 13.7 2.5 0.14 12.1 2.5 1.9 1 0 0 1 1 1 0 PHD-finger Spore_YtrH PF14034.6 EGB02719.1 - 0.076 13.2 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Sporulation protein YtrH DMRL_synthase PF00885.19 EGB02720.1 - 1.5e-17 63.7 0.0 2.9e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Methyltransf_22 PF13383.6 EGB02720.1 - 6.2e-10 39.1 0.0 8.6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EGB02720.1 - 6.8e-06 26.2 0.0 1.8e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase FkbM domain HC2 PF07382.11 EGB02721.1 - 0.013 15.6 106.6 0.023 14.8 106.6 1.4 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Pkinase PF00069.25 EGB02722.1 - 5.1e-33 114.6 0.0 3.1e-18 66.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain cNMP_binding PF00027.29 EGB02722.1 - 4.5e-30 103.6 0.5 7.3e-12 45.2 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGB02722.1 - 2e-13 50.2 0.0 2.6e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Mpv17_PMP22 PF04117.12 EGB02722.1 - 3.3e-07 30.4 0.0 7.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family CCDC-167 PF15188.6 EGB02722.1 - 0.62 10.4 4.3 1.5 9.2 4.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1192 PF06698.11 EGB02722.1 - 0.7 10.0 6.5 1.8 8.7 6.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TLD PF07534.16 EGB02723.1 - 4.1e-06 27.1 0.0 6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 TLD DNA_methylase PF00145.17 EGB02724.1 - 0.00029 20.3 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF1938 PF09153.10 EGB02725.1 - 0.27 11.4 0.0 0.49 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Ank_2 PF12796.7 EGB02726.1 - 1.3e-16 61.0 2.4 2.5e-08 34.4 0.2 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB02726.1 - 3.8e-08 33.0 0.4 0.0022 18.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB02726.1 - 1.5e-06 28.4 6.0 0.00078 19.7 1.6 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB02726.1 - 2.7e-05 24.6 0.5 5e-05 23.8 0.1 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB02726.1 - 0.0015 18.9 7.0 0.31 11.6 0.3 2.8 3 0 0 3 3 3 2 Ankyrin repeat Se-cys_synth_N PF12390.8 EGB02726.1 - 3 8.1 13.8 2.9 8.2 5.0 2.9 2 2 1 3 3 3 0 Selenocysteine synthase N terminal ABC_tran PF00005.27 EGB02727.1 - 3.7e-06 27.5 0.0 4.4e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGB02727.1 - 0.00029 20.5 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB02727.1 - 0.0072 16.3 0.1 0.0086 16.0 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGB02727.1 - 0.0083 16.5 0.6 0.012 16.0 0.6 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGB02727.1 - 0.017 15.7 0.1 0.021 15.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGB02727.1 - 0.022 14.6 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EGB02727.1 - 0.025 14.5 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 EGB02727.1 - 0.025 14.8 0.1 0.036 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGB02727.1 - 0.047 12.8 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EGB02727.1 - 0.055 13.0 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB02727.1 - 0.055 13.6 0.1 0.072 13.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB02727.1 - 0.073 13.6 0.0 0.087 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EGB02727.1 - 0.09 12.8 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Dynamin family AAA_30 PF13604.6 EGB02727.1 - 0.21 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGB02727.1 - 0.23 11.6 0.1 0.31 11.1 0.1 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EGB02727.1 - 0.23 11.7 0.1 0.31 11.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGB02727.1 - 0.26 11.0 0.1 0.32 10.7 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EGB02727.1 - 0.28 10.8 0.1 0.36 10.4 0.1 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_PrkA PF08298.11 EGB02727.1 - 0.32 9.9 0.1 0.41 9.5 0.1 1.1 1 0 0 1 1 1 0 PrkA AAA domain Proteasome PF00227.26 EGB02728.1 - 3.9e-22 78.7 0.2 5.5e-22 78.2 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB02728.1 - 2.4e-11 43.1 0.0 6.8e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF309 PF03745.14 EGB02729.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) CBFD_NFYB_HMF PF00808.23 EGB02729.1 - 0.19 12.1 0.1 5 7.5 0.0 2.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GTP_EFTU PF00009.27 EGB02732.1 - 1.3e-29 103.2 3.4 8.3e-28 97.2 3.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGB02732.1 - 1.1e-07 31.9 0.1 1.8e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGB02732.1 - 0.0018 18.4 0.0 0.037 14.1 0.0 2.2 2 0 0 2 2 2 1 Dynamin family PduV-EutP PF10662.9 EGB02732.1 - 0.0031 17.3 0.1 2.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EGB02732.1 - 0.0037 17.5 0.0 0.0056 16.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGB02732.1 - 0.004 17.1 0.2 2.7 7.9 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGB02732.1 - 0.024 15.2 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGB02732.1 - 0.039 13.4 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 EGB02732.1 - 0.052 13.1 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Ras family AAA_29 PF13555.6 EGB02732.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 EGB02732.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Spt46 PF17734.1 EGB02732.1 - 0.26 11.1 1.9 12 5.6 0.3 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 Radical_SAM PF04055.21 EGB02733.1 - 0.0093 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Ank_4 PF13637.6 EGB02735.1 - 5.6e-12 45.9 0.8 9.7e-07 29.2 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB02735.1 - 4e-08 33.7 0.2 9.8e-08 32.5 0.2 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB02735.1 - 5.9e-07 29.3 0.3 0.013 16.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGB02735.1 - 4.3e-06 26.9 0.6 0.66 10.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB02735.1 - 6.2e-06 26.4 1.5 0.005 17.1 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) KRTAP PF11759.8 EGB02736.1 - 0.00014 22.3 66.1 1.8e+04 -25.6 66.1 3.4 1 1 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 EGB02736.1 - 0.065 13.4 64.0 1.8e+04 -26.9 64.0 3.7 1 1 0 1 1 1 0 Keratin type II head Helicase_C_4 PF13871.6 EGB02737.1 - 2.1e-70 237.5 2.4 2.4e-70 237.3 2.4 1.0 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue Helicase_C PF00271.31 EGB02737.1 - 0.49 10.8 0.1 0.49 10.8 0.1 2.2 2 1 0 2 2 2 0 Helicase conserved C-terminal domain Peptidase_C1 PF00112.23 EGB02738.1 - 5e-66 222.9 0.8 5.7e-66 222.7 0.8 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB02738.1 - 1.2e-05 24.3 2.5 0.0057 15.5 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family ACT PF01842.25 EGB02739.1 - 0.00035 20.3 0.1 0.00067 19.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain Pkinase PF00069.25 EGB02739.1 - 0.047 13.0 0.1 0.065 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein kinase domain DNA_pol3_a_NI PF14480.6 EGB02740.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I PP2C PF00481.21 EGB02741.1 - 1.8e-39 136.0 0.0 2.4e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB02741.1 - 1.5e-05 24.7 0.2 4.9e-05 23.1 0.2 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB02741.1 - 0.00016 21.7 0.2 0.015 15.2 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) HMA PF00403.26 EGB02742.1 - 1e-70 234.1 5.0 2.6e-11 43.8 0.0 6.6 6 0 0 6 6 6 6 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 EGB02742.1 - 1.1e-44 152.1 0.5 1.1e-44 152.1 0.5 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGB02742.1 - 7.9e-38 130.8 6.0 7.9e-38 130.8 6.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGB02742.1 - 0.021 14.6 1.1 0.036 13.8 1.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PAP2 PF01569.21 EGB02742.1 - 0.059 13.1 1.0 0.19 11.5 1.0 1.8 1 0 0 1 1 1 0 PAP2 superfamily SCVP PF17619.2 EGB02742.1 - 0.15 12.9 0.1 43 5.1 0.0 2.4 2 0 0 2 2 2 0 Secreted clade V proteins DUF5302 PF17227.2 EGB02742.1 - 0.74 10.9 6.3 16 6.6 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5302) BON PF04972.17 EGB02742.1 - 0.96 9.8 18.1 1.8 8.9 1.5 5.2 5 0 0 5 5 5 0 BON domain DUF2840 PF11000.8 EGB02742.1 - 3 7.6 5.5 1.1e+02 2.6 0.1 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF2840) Fer2_BFD PF04324.15 EGB02742.1 - 4.4 7.7 15.9 1.4e+02 3.0 1.0 6.2 6 0 0 6 6 6 0 BFD-like [2Fe-2S] binding domain Sulfatase PF00884.23 EGB02743.1 - 6.7e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase RdRP PF05183.12 EGB02743.1 - 1.3e-10 40.6 0.0 2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Methyltransf_23 PF13489.6 EGB02743.1 - 9.4e-07 28.8 0.0 2.8e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB02743.1 - 1.1e-06 29.2 0.0 5.9e-06 26.8 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB02743.1 - 0.00074 20.2 0.0 0.0035 18.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Glyco_transf_34 PF05637.12 EGB02743.1 - 0.0028 17.4 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Methyltransf_25 PF13649.6 EGB02743.1 - 0.013 16.2 0.0 0.11 13.2 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain DUF4976 PF16347.5 EGB02743.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) ABC_tran PF00005.27 EGB02744.1 - 1.2e-20 74.5 0.0 1.7e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGB02744.1 - 3.6e-06 26.5 1.1 5e-06 26.1 1.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 EGB02744.1 - 0.0002 21.2 0.2 0.46 10.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB02744.1 - 0.011 16.2 0.1 0.011 16.2 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGB02744.1 - 0.019 14.7 1.6 0.055 13.2 0.4 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGB02744.1 - 0.028 14.0 1.0 0.11 12.1 0.5 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGB02744.1 - 0.053 14.0 0.8 0.087 13.3 0.8 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB02744.1 - 0.1 12.5 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase Peptidase_C48 PF02902.19 EGB02745.1 - 1.1e-20 74.4 0.0 1.8e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MOZ_SAS PF01853.18 EGB02746.1 - 4.4e-73 244.8 0.0 6.2e-73 244.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGB02746.1 - 3.7e-16 58.5 0.0 8.3e-16 57.3 0.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGB02746.1 - 2e-13 50.0 0.2 3.9e-13 49.1 0.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EGB02746.1 - 0.064 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_60s PF00428.19 EGB02746.1 - 0.88 10.2 10.3 2 9.0 10.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein EF-hand_7 PF13499.6 EGB02747.1 - 1.2e-24 86.6 8.4 1.6e-12 47.6 3.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB02747.1 - 1.5e-24 83.7 12.0 7.2e-08 31.4 2.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB02747.1 - 7.1e-19 67.4 10.2 5.2e-13 48.6 1.0 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EGB02747.1 - 1.2e-17 62.3 10.1 3.6e-08 32.7 0.1 4.0 4 1 1 5 5 5 3 EF-hand domain EF-hand_9 PF14658.6 EGB02747.1 - 5.5e-11 42.6 0.2 8.7e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB02747.1 - 3.4e-07 29.4 12.1 0.0082 15.6 0.2 4.0 3 1 0 3 3 3 2 EF hand EF-hand_14 PF17959.1 EGB02747.1 - 0.00027 21.2 1.1 0.45 10.9 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 EGB02747.1 - 0.0011 19.0 0.4 0.24 11.3 0.0 3.1 1 1 0 2 2 2 1 Caleosin related protein SurA_N_2 PF13623.6 EGB02747.1 - 0.0011 18.8 1.1 0.6 10.0 0.1 2.3 1 1 0 2 2 2 2 SurA N-terminal domain Acetyltransf_11 PF13720.6 EGB02747.1 - 0.0038 17.7 0.4 0.12 12.9 0.1 2.8 1 1 1 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF3911 PF13050.6 EGB02747.1 - 0.0065 16.6 2.5 0.044 13.9 0.2 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3911) HTH_40 PF14493.6 EGB02747.1 - 0.0066 16.9 0.2 0.78 10.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain DUF2857 PF11198.8 EGB02747.1 - 0.019 14.7 0.0 0.052 13.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2857) EF-hand_4 PF12763.7 EGB02747.1 - 0.02 14.8 4.0 0.39 10.7 1.5 2.9 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Ribosomal_S3Ae PF01015.18 EGB02747.1 - 0.049 13.2 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal S3Ae family SUB1_ProdP9 PF18213.1 EGB02747.1 - 0.052 13.4 0.2 0.095 12.6 0.2 1.4 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 AAA PF00004.29 EGB02747.1 - 0.096 13.1 2.4 0.31 11.5 2.3 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Gp-FAR-1 PF05823.12 EGB02747.1 - 0.1 13.0 0.8 0.45 10.9 0.0 2.2 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApbA_C PF08546.11 EGB02747.1 - 0.14 12.4 0.4 9.2 6.5 0.0 2.3 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal FGAR-AT_linker PF18072.1 EGB02747.1 - 0.23 12.0 1.7 21 5.8 0.2 3.1 2 2 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain FabA PF07977.13 EGB02748.1 - 2.1e-32 111.6 0.0 2.4e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 EGB02748.1 - 0.0024 17.4 0.0 0.005 16.4 0.0 1.5 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGB02748.1 - 0.056 13.6 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase 4HBT PF03061.22 EGB02748.1 - 0.082 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily CDC48_2 PF02933.17 EGB02748.1 - 0.14 11.9 0.0 1.3 8.9 0.0 2.3 2 1 1 3 3 3 0 Cell division protein 48 (CDC48), domain 2 MFS_1 PF07690.16 EGB02749.1 - 1.2e-17 63.9 45.0 1.2e-17 63.9 45.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB02749.1 - 1.5e-07 30.7 19.8 2e-06 26.9 8.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EGB02749.1 - 0.014 13.7 0.9 0.026 12.8 0.9 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2109 PF09882.9 EGB02750.1 - 0.026 14.6 0.3 0.05 13.6 0.3 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) MS_channel PF00924.18 EGB02750.1 - 0.15 11.5 0.2 0.24 10.9 0.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Sel1 PF08238.12 EGB02752.1 - 2.6e-20 72.4 10.6 1.8e-08 34.8 0.2 4.0 4 1 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 EGB02752.1 - 0.00017 22.2 9.8 0.0024 18.5 2.8 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02752.1 - 0.016 15.0 0.2 0.016 15.0 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB02752.1 - 0.04 14.2 5.9 0.051 13.9 1.1 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF410 PF04190.13 EGB02752.1 - 0.059 13.2 0.1 0.1 12.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF410) TPR_2 PF07719.17 EGB02752.1 - 0.063 13.4 0.4 0.063 13.4 0.4 4.3 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02752.1 - 0.063 13.2 0.1 0.063 13.2 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02752.1 - 1.5 9.6 5.0 72 4.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02752.1 - 4 7.9 6.6 1 9.7 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 EGB02753.1 - 8.8e-23 80.3 11.4 7.2e-08 32.9 0.4 4.2 4 0 0 4 4 4 4 Sel1 repeat AAA_lid_10 PF17872.1 EGB02753.1 - 0.46 10.6 2.0 5.5 7.2 0.2 2.2 1 1 0 2 2 2 0 AAA lid domain Optomotor-blind PF11078.8 EGB02755.1 - 0.041 14.5 3.0 0.2 12.2 3.0 2.2 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region MBD PF01429.19 EGB02755.1 - 0.067 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Methyl-CpG binding domain Agenet PF05641.12 EGB02755.1 - 0.12 12.9 0.3 0.3 11.6 0.3 1.6 1 0 0 1 1 1 0 Agenet domain Hexapep PF00132.24 EGB02756.1 - 8.7e-09 34.8 0.1 0.036 13.8 0.0 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB02756.1 - 0.011 15.4 0.0 5.5 6.8 0.0 3.4 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Baculo_helicase PF04735.12 EGB02757.1 - 0.16 9.4 0.1 0.23 9.0 0.1 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase Arm PF00514.23 EGB02758.1 - 7.9e-20 70.2 16.0 9.2e-07 28.7 1.2 4.8 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB02758.1 - 0.0075 16.6 8.1 0.0075 16.6 8.1 2.7 2 1 0 2 2 2 1 HEAT repeats Atx10homo_assoc PF09759.9 EGB02758.1 - 0.086 12.9 0.1 0.5 10.4 0.0 2.0 1 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain PP2C PF00481.21 EGB02759.1 - 6.5e-07 29.2 0.1 7.7e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EGB02760.1 - 5.4e-56 190.1 0.2 6.3e-56 189.9 0.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB02760.1 - 0.0032 17.4 0.1 0.056 13.4 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGB02760.1 - 0.0083 15.8 0.0 0.028 14.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Glyco_transf_64 PF09258.10 EGB02763.1 - 2.4e-28 99.1 0.0 4.5e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain ERp29 PF07749.12 EGB02763.1 - 4.3e-14 53.2 0.0 1e-13 52.0 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin PF00085.20 EGB02763.1 - 1.7e-09 37.6 0.0 0.00032 20.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin PhyH PF05721.13 EGB02763.1 - 0.00025 21.4 0.0 0.00065 20.0 0.0 1.7 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) OST3_OST6 PF04756.13 EGB02763.1 - 0.0065 15.8 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Ribosomal_L35Ae PF01247.18 EGB02764.1 - 3.8e-44 148.8 0.8 4.3e-44 148.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EGB02764.1 - 0.014 15.6 0.1 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 RimM N-terminal domain PseudoU_synth_2 PF00849.22 EGB02765.1 - 3.2e-21 76.1 0.0 4.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase 3HCDH_N PF02737.18 EGB02766.1 - 3.3e-53 180.3 0.1 4.4e-53 179.8 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGB02766.1 - 1.9e-30 105.3 0.0 4.7e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGB02766.1 - 0.0012 19.1 3.3 0.0084 16.3 3.3 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EGB02766.1 - 0.011 15.1 1.0 0.022 14.1 0.7 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGB02766.1 - 0.013 15.0 0.4 0.022 14.3 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EGB02766.1 - 0.048 14.3 3.5 0.18 12.4 3.5 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MORN PF02493.20 EGB02766.1 - 0.13 12.2 0.3 0.29 11.1 0.3 1.6 1 0 0 1 1 1 0 MORN repeat Tfb5 PF06331.12 EGB02768.1 - 7.6e-15 54.7 0.0 1.7e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ApbA PF02558.16 EGB02769.1 - 1.9e-19 69.8 0.0 2.6e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGB02769.1 - 2.1e-07 31.2 0.0 3.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Rossmann-like PF10727.9 EGB02769.1 - 0.0026 17.6 0.1 0.0047 16.8 0.1 1.4 1 0 0 1 1 1 1 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 EGB02769.1 - 0.13 11.9 0.4 0.19 11.3 0.4 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glucosamine_iso PF01182.20 EGB02770.1 - 0.00057 19.8 0.0 0.00057 19.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glucosamine_iso PF01182.20 EGB02771.1 - 2.8e-06 27.4 0.0 4.6e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase TrmO PF01980.16 EGB02775.1 - 1.4e-38 131.7 0.0 1.6e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 tRNA-methyltransferase O Sulphotransf PF09037.10 EGB02776.1 - 1.5e-08 34.5 0.2 8.3e-07 28.8 0.2 2.5 1 1 0 1 1 1 1 Stf0 sulphotransferase Sulfotransfer_3 PF13469.6 EGB02776.1 - 0.0021 18.5 0.1 0.0072 16.7 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB02776.1 - 0.048 13.1 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase domain Trypan_PARP PF05887.11 EGB02777.1 - 0.026 14.5 13.4 0.028 14.4 9.6 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Aa_trans PF01490.18 EGB02780.1 - 1.5e-38 132.6 5.8 2.7e-38 131.8 5.8 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Pepsin-I3 PF06394.13 EGB02780.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Sel1 PF08238.12 EGB02781.1 - 5.8e-21 74.5 6.9 1.8e-08 34.8 0.3 4.2 4 1 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 EGB02781.1 - 0.048 14.3 4.5 0.35 11.6 0.8 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02781.1 - 0.18 12.5 4.7 1.8 9.4 0.0 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02781.1 - 1.8 8.9 7.5 13 6.2 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SlyX PF04102.12 EGB02782.1 - 0.23 12.1 1.1 0.43 11.2 1.1 1.4 1 0 0 1 1 1 0 SlyX Coprogen_oxidas PF01218.18 EGB02784.1 - 2.6e-124 413.8 0.2 3e-124 413.5 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase LPD7 PF18821.1 EGB02784.1 - 0.062 13.4 0.1 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 ABC_tran PF00005.27 EGB02785.1 - 8.2e-19 68.5 0.0 1.2e-18 68.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB02785.1 - 1.2e-06 29.0 0.6 1.9e-06 28.4 0.6 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB02785.1 - 5.3e-05 23.2 0.0 0.065 13.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB02785.1 - 9.9e-05 22.3 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGB02785.1 - 0.0001 21.9 0.6 0.00033 20.3 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EGB02785.1 - 0.00023 21.6 0.0 0.0027 18.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB02785.1 - 0.0003 21.1 0.2 0.0028 17.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB02785.1 - 0.00077 19.1 0.2 0.0026 17.4 0.2 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB02785.1 - 0.0038 17.2 0.5 0.0099 15.8 0.1 1.8 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 EGB02785.1 - 0.004 17.3 0.1 0.0084 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGB02785.1 - 0.0055 17.2 0.0 0.0073 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGB02785.1 - 0.0061 16.0 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EGB02785.1 - 0.0083 16.4 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGB02785.1 - 0.012 15.4 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 EGB02785.1 - 0.015 14.3 0.2 0.023 13.7 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGB02785.1 - 0.015 15.0 0.5 0.03 14.1 0.2 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGB02785.1 - 0.031 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 EGB02785.1 - 0.038 14.5 0.4 0.084 13.4 0.1 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 EGB02785.1 - 0.047 13.3 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGB02785.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.6 EGB02785.1 - 0.062 13.6 0.8 0.14 12.5 0.8 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB02785.1 - 0.065 12.6 0.2 0.13 11.6 0.1 1.5 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGB02785.1 - 0.094 12.7 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGB02785.1 - 0.095 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGB02785.1 - 0.097 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EGB02785.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EGB02785.1 - 0.1 12.6 0.1 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGB02785.1 - 0.11 12.5 0.0 2.7 8.1 0.0 2.5 2 1 1 3 3 3 0 AAA domain MobB PF03205.14 EGB02785.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 EGB02785.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 EGB02785.1 - 0.15 10.9 0.1 0.27 10.1 0.0 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 EGB02785.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EGB02785.1 - 0.18 12.2 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EGB02785.1 - 0.25 11.2 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Ion_trans PF00520.31 EGB02786.1 - 5.2e-13 48.8 7.5 6.6e-13 48.4 7.5 1.2 1 0 0 1 1 1 1 Ion transport protein DUF2207 PF09972.9 EGB02786.1 - 0.04 12.7 1.3 0.049 12.4 1.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TssO PF17561.2 EGB02786.1 - 0.066 13.3 0.2 0.066 13.3 0.2 2.6 3 0 0 3 3 3 0 Type VI secretion system, TssO PRA-PH PF01503.17 EGB02786.1 - 0.83 10.1 2.1 16 6.0 0.1 2.3 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Pterin_bind PF00809.22 EGB02787.1 - 1.9e-33 116.1 0.0 2.3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme MtrH PF02007.18 EGB02787.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit S-methyl_trans PF02574.16 EGB02788.1 - 1.1e-53 182.8 0.0 1.4e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase STT3 PF02516.14 EGB02789.1 - 4e-17 62.3 2.7 4.4e-17 62.2 2.7 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Oxidored_molyb PF00174.19 EGB02790.1 - 1.9e-46 157.8 0.0 3e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGB02790.1 - 1.1e-44 151.8 0.0 1.9e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EGB02790.1 - 4.5e-22 78.0 0.1 1.4e-21 76.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAM176 PF14851.6 EGB02791.1 - 0.022 14.4 5.0 0.022 14.4 5.0 1.9 2 0 0 2 2 2 0 FAM176 family WRNPLPNID PF15017.6 EGB02791.1 - 0.022 15.6 5.7 0.022 15.6 5.7 1.9 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RNA_pol_3_Rpc31 PF11705.8 EGB02791.1 - 0.036 14.3 12.9 0.045 14.0 12.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 EGB02791.1 - 0.044 13.5 14.1 0.064 13.0 14.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MarC PF01914.17 EGB02791.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 MarC family integral membrane protein DUF3169 PF11368.8 EGB02791.1 - 0.25 10.8 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) CENP-B_dimeris PF09026.10 EGB02791.1 - 0.56 10.6 12.7 0.97 9.9 12.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Presenilin PF01080.17 EGB02791.1 - 2.6 6.7 6.1 3 6.5 6.1 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 EGB02791.1 - 4.7 7.2 9.4 5.8 6.9 9.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GEN1_C PF18380.1 EGB02791.1 - 5.8 7.9 14.2 1.4 9.9 6.2 2.1 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF4611 PF15387.6 EGB02791.1 - 7.8 6.8 15.7 16 5.8 15.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EGB02791.1 - 8.5 5.6 19.6 17 4.6 19.5 1.5 1 1 0 1 1 1 0 NOA36 protein SAPS PF04499.15 EGB02791.1 - 9.6 4.9 8.1 10 4.8 8.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ARL2_Bind_BART PF11527.8 EGB02792.1 - 6.5e-06 26.2 0.5 8.6e-05 22.6 0.5 2.1 1 1 0 1 1 1 1 The ARF-like 2 binding protein BART Amidohydro_2 PF04909.14 EGB02793.1 - 2.2e-11 44.1 0.1 2.6e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF3086 PF11285.8 EGB02793.1 - 0.024 13.7 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) WW PF00397.26 EGB02794.1 - 9.3e-13 48.0 17.7 1e-06 28.7 2.7 3.4 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 EGB02794.1 - 0.74 10.1 8.8 1.9 8.8 1.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain PP-binding PF00550.25 EGB02795.1 - 1.5e-12 47.6 0.6 2.7e-12 46.8 0.6 1.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGB02795.1 - 0.071 13.3 0.4 0.096 12.9 0.3 1.3 1 1 0 1 1 1 0 Acyl-carrier ABATE PF07336.11 EGB02796.1 - 0.018 15.7 1.9 0.03 15.0 1.9 1.3 1 0 0 1 1 1 0 Putative stress-induced transcription regulator DUF485 PF04341.12 EGB02796.1 - 0.083 12.9 0.9 19 5.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Sulfotransfer_3 PF13469.6 EGB02797.1 - 0.07 13.5 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase family SWIM PF04434.17 EGB02798.1 - 0.0061 16.2 0.4 0.015 14.9 0.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-C3H1 PF10650.9 EGB02798.1 - 0.87 9.4 3.1 1.9 8.3 3.1 1.6 1 0 0 1 1 1 0 Putative zinc-finger domain Pentapeptide_4 PF13599.6 EGB02799.1 - 0.05 13.8 0.0 0.076 13.2 0.0 1.2 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) RNA_POL_M_15KD PF02150.16 EGB02800.1 - 1.4e-06 28.0 1.0 1.4e-06 28.0 1.0 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EGB02800.1 - 0.00016 21.5 2.2 0.00016 21.5 2.2 3.5 2 2 0 2 2 2 1 Transcription factor S-II (TFIIS) DZR PF12773.7 EGB02800.1 - 0.0025 17.8 0.7 0.0025 17.8 0.7 2.7 2 1 1 3 3 3 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGB02800.1 - 0.066 13.3 8.4 2.2 8.5 1.4 3.3 3 1 0 3 3 3 0 Zinc ribbon domain Nudix_N_2 PF14803.6 EGB02800.1 - 0.09 12.7 14.7 0.27 11.2 0.2 4.1 4 0 0 4 4 4 0 Nudix N-terminal zf-ribbon_3 PF13248.6 EGB02800.1 - 0.092 12.2 16.4 0.74 9.3 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain RecR PF02132.15 EGB02800.1 - 0.2 11.2 0.3 0.2 11.2 0.3 2.8 3 1 0 3 3 3 0 RecR protein DNA_RNApol_7kD PF03604.13 EGB02800.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.7 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Lar_restr_allev PF14354.6 EGB02800.1 - 0.52 10.7 8.2 5 7.6 0.8 2.5 1 1 2 3 3 3 0 Restriction alleviation protein Lar zf-NADH-PPase PF09297.11 EGB02800.1 - 0.6 9.8 0.2 0.6 9.8 0.2 3.4 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 EGB02800.1 - 1.4 9.0 8.6 1.9 8.5 0.5 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 EGB02800.1 - 1.7 8.3 10.7 9.7 5.8 0.0 4.0 3 1 0 4 4 4 0 TFIIB zinc-binding zf-LITAF-like PF10601.9 EGB02800.1 - 3.1 8.1 12.3 0.27 11.5 1.6 2.9 2 1 0 3 3 3 0 LITAF-like zinc ribbon domain eIF-5_eIF-2B PF01873.17 EGB02800.1 - 4 7.4 7.6 9.4 6.1 0.4 2.4 2 1 1 3 3 3 0 Domain found in IF2B/IF5 ADD_ATRX PF17981.1 EGB02800.1 - 6.8 6.6 9.2 2.9 7.8 0.3 3.1 2 1 1 3 3 3 0 Cysteine Rich ADD domain BRCT PF00533.26 EGB02801.1 - 4.5e-07 30.2 0.0 0.00043 20.6 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_6 PF13921.6 EGB02801.1 - 0.0033 17.7 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain PDE8 PF08629.10 EGB02801.1 - 0.069 13.2 0.3 6.6 6.8 0.1 2.9 2 0 0 2 2 2 0 PDE8 phosphodiesterase HTH_29 PF13551.6 EGB02803.1 - 0.056 13.5 0.8 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix SRCR PF00530.18 EGB02805.1 - 1.3e-05 25.6 0.1 3.5e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Pkinase PF00069.25 EGB02809.1 - 5.2e-59 199.8 0.0 6.1e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02809.1 - 6.7e-31 107.5 0.0 8.8e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB02809.1 - 0.00073 18.9 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-B_box PF00643.24 EGB02811.1 - 0.026 14.7 11.1 0.064 13.4 11.1 1.7 1 0 0 1 1 1 0 B-box zinc finger DUF724 PF05266.14 EGB02811.1 - 0.1 12.4 5.6 0.5 10.2 3.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) IQ PF00612.27 EGB02811.1 - 0.11 12.3 26.5 2.2 8.3 0.1 6.9 6 0 0 6 6 6 0 IQ calmodulin-binding motif Cupin_4 PF08007.12 EGB02813.1 - 8.5e-05 22.2 0.0 0.00019 21.0 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 EGB02813.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain Mad3_BUB1_I PF08311.12 EGB02815.1 - 1.2e-22 80.2 0.0 5.9e-22 78.0 0.0 1.8 1 1 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGB02815.1 - 0.031 14.4 0.5 0.074 13.2 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02815.1 - 4.7 8.3 9.9 1.1 10.2 1.6 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.23 EGB02816.1 - 4.5e-57 193.4 0.1 5.3e-57 193.1 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGB02816.1 - 9.5e-05 22.5 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB02816.1 - 0.0029 17.4 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGB02816.1 - 0.0039 16.9 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 EGB02816.1 - 0.066 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L6 PF00347.23 EGB02818.1 - 1.9e-24 86.1 0.4 8.5e-15 55.2 0.1 2.4 2 1 0 2 2 2 2 Ribosomal protein L6 ABC_tran PF00005.27 EGB02819.1 - 9.8e-21 74.7 0.0 1.4e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGB02819.1 - 3.4e-11 43.3 0.1 4.9e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 EGB02819.1 - 0.00029 20.5 0.2 0.00091 18.9 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB02819.1 - 0.0041 17.0 0.3 0.055 13.3 0.2 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB02819.1 - 0.012 15.1 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB02819.1 - 0.018 14.8 6.7 0.051 13.3 6.7 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB02819.1 - 0.045 13.1 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EGB02819.1 - 0.055 13.7 0.2 0.11 12.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB02819.1 - 0.083 13.4 0.3 0.13 12.7 0.3 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB02819.1 - 0.13 12.6 7.5 0.066 13.6 2.7 2.7 2 1 1 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 EGB02819.1 - 0.16 12.2 0.6 0.46 10.6 0.5 1.8 1 1 0 1 1 1 0 AAA domain VCBS PF13517.6 EGB02820.1 - 2.6e-40 136.8 75.0 2.9e-11 43.8 8.9 6.1 2 2 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB02820.1 - 9.9e-07 28.8 68.5 0.00024 21.2 3.2 7.4 7 0 0 7 7 7 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 EGB02820.1 - 0.0083 15.5 28.8 0.76 9.1 0.4 6.3 3 2 4 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region DUF3821 PF12863.7 EGB02820.1 - 0.12 12.2 1.5 4.9 7.0 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3821) PHD PF00628.29 EGB02821.1 - 0.0095 15.8 6.4 0.017 15.0 6.4 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EGB02821.1 - 0.01 15.7 0.6 0.01 15.7 0.6 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 EGB02821.1 - 0.012 15.6 4.8 0.31 11.1 4.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF4407 PF14362.6 EGB02821.1 - 0.39 10.0 7.0 0.044 13.1 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-PHD-like PF15446.6 EGB02821.1 - 0.95 9.1 4.1 1.8 8.2 4.1 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 EGB02821.1 - 7.8 6.9 6.4 14 6.1 6.4 1.5 1 0 0 1 1 1 0 Ring finger domain Ribosomal_L11_N PF03946.14 EGB02822.1 - 6.6e-26 89.9 0.3 9.1e-26 89.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGB02822.1 - 5.3e-23 81.3 0.0 7.8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NOA36 PF06524.12 EGB02822.1 - 0.42 9.9 5.0 0.5 9.6 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein BLACT_WH PF17778.1 EGB02824.1 - 1.3e-11 44.3 0.1 3.8e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Metallophos PF00149.28 EGB02826.1 - 1.2e-36 127.1 0.0 1.4e-36 126.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PHD PF00628.29 EGB02827.1 - 7.4e-06 25.8 2.6 2.2e-05 24.3 2.6 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EGB02827.1 - 1.3 9.0 3.6 8.7 6.3 1.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EGB02827.1 - 1.4 9.3 3.0 2.8 8.3 3.0 1.5 1 0 0 1 1 1 0 C1 domain EF-hand_1 PF00036.32 EGB02828.1 - 5.2e-14 50.7 6.8 0.00075 18.9 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGB02828.1 - 1.7e-13 49.3 7.4 0.00033 20.3 0.0 4.1 4 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGB02828.1 - 4.9e-13 49.3 3.0 2.7e-08 34.2 0.4 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB02828.1 - 8.7e-08 31.9 7.1 0.00012 21.8 1.7 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB02828.1 - 1.2e-07 30.9 5.7 0.0036 16.7 0.3 3.4 3 0 0 3 3 3 2 EF hand Msg2_C PF12373.8 EGB02828.1 - 0.00011 21.5 1.9 0.29 10.6 0.4 2.4 2 0 0 2 2 2 2 Major surface glycoprotein 2 C terminal EF-hand_9 PF14658.6 EGB02828.1 - 0.002 18.4 0.6 4.9 7.6 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 EGB02828.1 - 0.0078 16.4 1.0 0.18 12.0 1.0 2.6 2 1 0 2 2 2 1 Dockerin type I domain DWNN PF08783.11 EGB02828.1 - 0.032 14.5 0.1 3.2 8.1 0.0 2.4 1 1 1 2 2 2 0 DWNN domain DIX PF00778.17 EGB02828.1 - 0.1 12.4 1.3 2.4 8.1 0.1 3.2 2 2 2 4 4 4 0 DIX domain Lipase_GDSL_2 PF13472.6 EGB02829.1 - 1.2e-15 58.4 0.2 2.3e-15 57.4 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RRM_1 PF00076.22 EGB02829.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ku PF02735.16 EGB02829.1 - 0.28 10.8 0.0 0.46 10.2 0.0 1.2 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain FKBP_C PF00254.28 EGB02830.1 - 3.1e-16 59.5 0.0 3.7e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 EGB02831.1 - 6e-20 71.7 0.0 4e-17 62.4 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02831.1 - 1.4e-13 50.8 0.0 1.2e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF973 PF06157.11 EGB02832.1 - 0.0055 15.8 0.0 0.0075 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Ank_2 PF12796.7 EGB02834.1 - 1.1e-17 64.3 0.0 1.6e-07 31.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB02834.1 - 2.7e-15 56.5 0.0 4.1e-06 27.2 0.0 3.9 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB02834.1 - 4.4e-13 48.1 0.5 0.95 10.2 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EGB02834.1 - 2.2e-10 40.6 0.4 0.029 14.7 0.0 4.8 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB02834.1 - 4.5e-09 36.4 0.9 4.6 7.9 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat MBD PF01429.19 EGB02835.1 - 1.4e-06 27.9 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Methyl-CpG binding domain Kinesin PF00225.23 EGB02836.1 - 3.4e-94 315.5 0.1 3.8e-94 315.3 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB02836.1 - 1.1e-21 77.3 0.0 2.7e-21 76.1 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding AAA_30 PF13604.6 EGB02836.1 - 0.00056 19.7 0.0 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGB02836.1 - 0.094 13.0 0.2 0.44 10.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain DUF5420 PF17457.2 EGB02836.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5420) PhoH PF02562.16 EGB02836.1 - 0.17 11.3 0.6 6.2 6.2 0.3 2.6 1 1 1 2 2 2 0 PhoH-like protein Mpp10 PF04006.12 EGB02838.1 - 0.00032 19.3 30.4 0.0019 16.8 18.6 2.5 2 1 0 2 2 2 2 Mpp10 protein Drc1-Sld2 PF11719.8 EGB02838.1 - 0.0012 18.5 17.0 0.12 11.9 0.0 2.6 2 1 1 3 3 3 2 DNA replication and checkpoint protein BUD22 PF09073.10 EGB02838.1 - 0.0014 18.0 14.7 0.0014 18.0 14.7 2.8 2 1 0 2 2 2 1 BUD22 RNA_pol_3_Rpc31 PF11705.8 EGB02838.1 - 0.0032 17.8 18.6 0.0032 17.8 18.6 3.6 4 0 0 4 4 4 2 DNA-directed RNA polymerase III subunit Rpc31 Merozoite_SPAM PF07133.11 EGB02838.1 - 0.0066 16.5 32.9 0.0066 16.5 32.9 2.5 2 1 0 2 2 2 1 Merozoite surface protein (SPAM) SDA1 PF05285.12 EGB02838.1 - 0.0077 15.7 19.0 0.0077 15.7 19.0 2.8 2 1 0 2 2 2 1 SDA1 RR_TM4-6 PF06459.12 EGB02838.1 - 0.0084 16.0 8.3 0.0084 16.0 8.3 2.2 2 1 0 2 2 2 1 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 EGB02838.1 - 0.81 8.6 8.5 0.059 12.3 2.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 EGB02838.1 - 4.7 7.5 19.7 0.11 12.8 8.1 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF485 PF04341.12 EGB02839.1 - 0.19 11.7 1.1 27 4.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Synaptobrevin PF00957.21 EGB02841.1 - 1.9e-20 72.4 0.3 2e-20 72.4 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2937 PF11157.8 EGB02841.1 - 0.0036 17.0 0.1 0.0041 16.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Nsp1_C PF05064.13 EGB02841.1 - 0.028 14.2 1.4 0.24 11.2 0.1 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region MtrB PF05440.12 EGB02841.1 - 0.08 13.4 1.0 2.1 8.8 1.0 2.0 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Peptidase_M17 PF00883.21 EGB02842.1 - 1e-96 323.9 3.0 1.4e-96 323.4 3.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain PALP PF00291.25 EGB02843.1 - 3.7e-32 111.9 9.1 4.7e-32 111.6 9.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme OB_NTP_bind PF07717.16 EGB02844.1 - 1.1e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Aldedh PF00171.22 EGB02846.1 - 6.6e-88 295.2 0.0 8.8e-48 162.9 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LSM PF01423.22 EGB02847.1 - 8.4e-17 60.6 0.1 8.3e-10 38.2 0.0 2.0 2 0 0 2 2 2 2 LSM domain EF1_GNE PF00736.19 EGB02848.1 - 3.3e-20 72.0 1.7 6.1e-20 71.2 1.7 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Pox_Ag35 PF03286.14 EGB02848.1 - 0.078 12.8 9.0 0.12 12.1 9.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAP PF07174.11 EGB02848.1 - 0.54 9.7 16.1 0.75 9.2 16.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CDC27 PF09507.10 EGB02848.1 - 0.77 9.1 13.7 1 8.7 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2486 PF10667.9 EGB02848.1 - 0.99 9.6 21.6 1.3 9.1 21.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF2868 PF11067.8 EGB02848.1 - 1.8 8.0 6.1 2.6 7.5 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Mitofilin PF09731.9 EGB02848.1 - 2.1 7.1 14.7 2.7 6.8 14.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Beta-lactamase PF00144.24 EGB02849.1 - 1e-06 28.2 7.3 8.3e-06 25.3 7.3 2.1 1 1 0 1 1 1 1 Beta-lactamase ketoacyl-synt PF00109.26 EGB02850.1 - 2.9e-42 145.0 1.8 2.9e-42 145.0 1.8 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 EGB02850.1 - 9.4e-28 96.4 0.5 1.1e-13 51.3 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 EGB02850.1 - 5.5e-22 78.0 1.4 1.1e-21 77.1 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EGB02850.1 - 2.3e-06 27.9 0.1 4.2e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain KR PF08659.10 EGB02850.1 - 0.0034 17.3 0.0 0.0076 16.2 0.0 1.7 1 0 0 1 1 1 1 KR domain RRP14 PF15459.6 EGB02850.1 - 7.8 7.2 14.2 16 6.2 14.2 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 VCBS PF13517.6 EGB02851.1 - 5.3e-45 151.8 111.8 3.8e-09 37.0 9.5 9.0 3 2 6 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AbfS_sensor PF18225.1 EGB02851.1 - 1.3e-06 28.2 0.0 13 5.8 0.0 6.1 6 0 0 6 6 6 1 Sensor histidine kinase (AbfS) sensor domain Notch PF00066.17 EGB02851.1 - 0.0011 19.4 4.6 0.0036 17.7 4.6 1.9 1 0 0 1 1 1 1 LNR domain Dockerin_1 PF00404.18 EGB02851.1 - 1.1 9.5 55.6 6 7.1 0.3 8.7 7 2 1 8 8 8 0 Dockerin type I domain Sel1 PF08238.12 EGB02852.1 - 1.6e-21 76.2 10.1 1.8e-08 34.8 0.1 4.3 4 1 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB02852.1 - 0.0042 17.7 6.9 0.033 14.8 2.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02852.1 - 0.047 13.5 0.2 0.047 13.5 0.2 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 EGB02852.1 - 0.14 12.3 0.5 0.14 12.3 0.5 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EGB02852.1 - 0.17 12.2 6.0 1.7 9.0 1.5 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02852.1 - 0.45 10.8 0.1 0.45 10.8 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat cNMP_binding PF00027.29 EGB02853.1 - 0.028 14.5 7.2 0.039 14.0 0.0 4.5 5 0 0 5 5 5 0 Cyclic nucleotide-binding domain DUF2877 PF11392.8 EGB02853.1 - 7.2 7.4 9.3 73 4.1 0.1 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2877) Cytochrom_B561 PF03188.16 EGB02854.1 - 4.8e-13 49.4 0.4 1.3e-12 48.0 0.4 1.8 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Xpo1 PF08389.12 EGB02854.1 - 2.6e-09 37.3 0.0 4.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Exportin 1-like protein MFS_1 PF07690.16 EGB02854.1 - 1.1e-07 31.2 40.1 1.1e-07 31.2 40.1 3.9 3 1 2 5 5 5 1 Major Facilitator Superfamily Pkinase PF00069.25 EGB02855.1 - 4.8e-63 213.0 0.0 5.5e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02855.1 - 1.7e-16 60.3 0.0 2.5e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB02855.1 - 9.9e-07 28.9 0.2 3.3e-05 23.9 0.3 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB02855.1 - 0.012 14.4 0.3 0.026 13.3 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGB02855.1 - 0.048 13.0 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB02855.1 - 0.091 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EGB02855.1 - 0.11 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EMP70 PF02990.16 EGB02856.1 - 2.2e-143 478.7 20.7 3.2e-143 478.1 20.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TPR_12 PF13424.6 EGB02857.1 - 7.9e-55 183.1 43.0 2.3e-17 63.0 4.4 4.5 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02857.1 - 1.7e-46 154.8 28.4 1e-08 34.7 0.3 7.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02857.1 - 1.2e-20 72.0 21.3 4.2e-05 23.3 0.1 6.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02857.1 - 1.1e-19 69.3 9.0 0.0024 17.6 0.2 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02857.1 - 1e-17 62.7 21.3 9e-05 22.3 0.6 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02857.1 - 1e-17 62.7 9.7 0.0099 16.0 0.0 5.7 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_4 PF07721.14 EGB02857.1 - 2.4e-12 46.2 18.2 0.02 15.4 0.0 7.7 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02857.1 - 1.4e-10 41.1 21.3 0.023 15.5 0.1 6.2 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02857.1 - 2.5e-09 37.2 9.5 0.11 13.2 0.2 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB02857.1 - 1.8e-08 34.2 5.9 4e-08 33.0 3.1 1.9 1 1 0 1 1 1 1 MalT-like TPR region Mob_Pre PF01076.19 EGB02857.1 - 1.2e-05 25.2 0.0 0.72 9.6 0.0 4.2 4 1 0 4 4 4 1 Plasmid recombination enzyme TPR_17 PF13431.6 EGB02857.1 - 4.7e-05 23.5 5.3 15 6.2 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02857.1 - 0.00033 21.2 28.0 0.0012 19.5 6.5 5.0 3 2 1 5 5 5 2 Tetratricopeptide repeat SPO22 PF08631.10 EGB02857.1 - 0.00047 19.7 0.2 0.035 13.6 0.1 2.2 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like DUF1955 PF09205.10 EGB02857.1 - 0.0011 18.7 0.1 25 4.6 0.0 4.5 1 1 3 5 5 5 0 Domain of unknown function (DUF1955) TPR_9 PF13371.6 EGB02857.1 - 0.0011 19.0 15.7 0.38 10.9 0.2 5.3 2 2 3 5 5 5 1 Tetratricopeptide repeat DUF4807 PF16065.5 EGB02857.1 - 0.0061 16.2 4.5 17 5.1 0.1 4.5 2 2 2 5 5 5 0 Domain of unknown function (DUF4807) YlmH_RBD PF17774.1 EGB02857.1 - 0.01 16.1 0.6 2.6 8.4 0.0 3.8 3 2 2 5 5 4 0 Putative RNA-binding domain in YlmH TPR_19 PF14559.6 EGB02857.1 - 0.011 16.3 16.2 0.38 11.3 2.5 4.8 1 1 5 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB02857.1 - 0.012 15.2 11.7 3.5 7.4 0.1 5.2 6 0 0 6 6 6 0 TPR repeat pKID PF02173.17 EGB02857.1 - 0.018 14.5 6.6 13 5.3 0.0 5.0 5 0 0 5 5 5 0 pKID domain TAtT PF16811.5 EGB02857.1 - 0.028 13.7 3.0 0.95 8.7 0.1 2.9 1 1 1 3 3 3 0 TRAP transporter T-component Wzy_C_2 PF11846.8 EGB02857.1 - 0.053 13.5 0.7 12 5.7 0.0 3.0 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal XdhC_CoxI PF02625.16 EGB02857.1 - 0.054 13.7 5.1 24 5.2 0.0 4.7 2 1 3 5 5 5 0 XdhC and CoxI family Lambda_tail_I PF06805.12 EGB02857.1 - 0.057 13.8 0.2 15 6.0 0.0 3.5 3 1 1 4 4 4 0 Bacteriophage lambda tail assembly protein I SMBP PF16785.5 EGB02857.1 - 0.096 12.9 7.3 1.5 9.1 2.1 2.5 2 0 0 2 2 2 0 Small metal-binding protein Tcf25 PF04910.14 EGB02857.1 - 0.11 11.6 0.2 24 3.9 0.0 3.6 2 1 2 4 4 4 0 Transcriptional repressor TCF25 Cortex-I_coil PF09304.10 EGB02857.1 - 0.21 11.8 1.7 1.8 8.8 0.0 2.8 2 2 1 3 3 3 0 Cortexillin I, coiled coil Fis1_TPR_C PF14853.6 EGB02857.1 - 1.3 9.2 7.6 8.2 6.6 0.2 4.4 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat PLA2_B PF01735.18 EGB02858.1 - 2.7e-06 26.1 0.3 2.4e-05 23.0 0.5 2.0 2 0 0 2 2 2 1 Lysophospholipase catalytic domain Patatin PF01734.22 EGB02858.1 - 0.00039 20.7 8.9 0.0093 16.2 8.9 2.8 1 1 0 1 1 1 1 Patatin-like phospholipase VCBS PF13517.6 EGB02860.1 - 1.2e-12 48.2 16.7 5.1e-07 30.2 5.8 3.2 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella vWF_A PF12450.8 EGB02860.1 - 0.14 12.1 1.1 4.4 7.3 0.2 3.1 3 0 0 3 3 3 0 von Willebrand factor Ribonuc_2-5A PF06479.12 EGB02860.1 - 0.32 11.2 1.7 6.4 7.0 0.4 2.9 2 1 1 3 3 3 0 Ribonuclease 2-5A Dockerin_1 PF00404.18 EGB02860.1 - 1.6 9.0 5.8 14 5.9 0.0 3.1 3 0 0 3 3 3 0 Dockerin type I domain PARP PF00644.20 EGB02861.1 - 1.3e-17 64.1 0.0 2.6e-17 63.1 0.0 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PhnA_Zn_Ribbon PF08274.12 EGB02863.1 - 0.019 14.9 0.0 0.019 14.9 0.0 4.6 5 1 0 5 5 5 0 PhnA Zinc-Ribbon zf-UDP PF14569.6 EGB02863.1 - 0.92 9.7 9.7 3 8.0 3.4 3.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 EGB02863.1 - 1 9.2 11.6 0.52 10.2 1.0 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGB02863.1 - 5.6 6.9 34.1 0.58 10.1 9.9 5.1 5 1 1 6 6 6 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 EGB02864.1 - 3.2e-29 102.1 0.0 4e-23 82.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain ELMO_CED12 PF04727.13 EGB02864.1 - 5.2e-15 56.0 0.0 9.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Pkinase_Tyr PF07714.17 EGB02864.1 - 1.2e-08 34.6 0.0 3.8e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase PH PF00169.29 EGB02864.1 - 0.085 13.4 0.0 0.2 12.2 0.0 1.7 1 1 0 1 1 1 0 PH domain SH3_3 PF08239.11 EGB02864.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain DUF3275 PF11679.8 EGB02864.1 - 4.8 7.1 5.2 9 6.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) C2 PF00168.30 EGB02866.1 - 2.4e-24 85.6 0.0 5.1e-12 46.0 0.0 2.8 3 0 0 3 3 3 2 C2 domain K_channel_TID PF07941.11 EGB02866.1 - 0.11 13.0 6.5 10 6.6 6.7 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DNA_pol_phi PF04931.13 EGB02866.1 - 6.8 4.7 12.4 9.6 4.2 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi GST_N PF02798.20 EGB02867.1 - 8.5e-07 29.2 0.0 2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB02867.1 - 0.00079 19.7 0.0 0.0025 18.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain WHEP-TRS PF00458.20 EGB02867.1 - 0.0026 17.9 0.6 0.0056 16.8 0.6 1.5 1 0 0 1 1 1 1 WHEP-TRS domain GST_N_3 PF13417.6 EGB02867.1 - 0.0032 17.8 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF5529 PF17669.1 EGB02867.1 - 0.038 14.0 0.1 0.038 14.0 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5529) SAP PF02037.27 EGB02868.1 - 5.3e-09 35.6 2.8 1e-08 34.8 2.8 1.5 1 0 0 1 1 1 1 SAP domain IMS PF00817.20 EGB02868.1 - 7.2e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf-C3HC4_3 PF13920.6 EGB02869.1 - 0.04 13.8 10.0 0.11 12.4 10.1 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EGB02869.1 - 1.1 9.4 9.4 2.7 8.1 9.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon Abhydrolase_2 PF02230.16 EGB02870.1 - 2.3e-12 47.2 0.0 5.4e-12 46.0 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Arylsulfotrans PF05935.11 EGB02870.1 - 2.8e-05 23.2 0.0 3.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Thioesterase PF00975.20 EGB02870.1 - 0.012 15.8 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 EGB02870.1 - 0.11 11.7 0.1 0.29 10.4 0.1 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 AfaD PF05775.12 EGB02871.1 - 0.017 15.6 0.0 0.051 14.0 0.0 1.7 2 0 0 2 2 2 0 Enterobacteria AfaD invasin protein STELLO PF03385.17 EGB02873.1 - 3.1e-15 55.9 0.0 4.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases PH PF00169.29 EGB02874.1 - 3.2e-07 30.8 0.0 5.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGB02874.1 - 0.04 14.3 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_1 PF00036.32 EGB02875.1 - 1.6e-21 74.2 16.0 2e-05 23.8 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB02875.1 - 3.3e-19 67.1 14.2 1.2e-05 24.9 0.6 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGB02875.1 - 3.6e-18 65.8 10.8 5.7e-10 39.5 1.6 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB02875.1 - 4.5e-16 58.4 14.4 1.1e-06 28.3 0.6 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB02875.1 - 8.8e-14 50.3 19.1 0.0024 17.3 1.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGB02875.1 - 0.00026 21.2 0.9 0.071 13.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGB02875.1 - 0.034 14.1 11.2 0.33 10.9 0.5 3.5 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Arrestin_N PF00339.29 EGB02876.1 - 1.1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain C2 PF00168.30 EGB02876.1 - 0.0003 21.0 0.0 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 C2 domain Phage_integrase PF00589.22 EGB02877.1 - 4.8e-06 26.5 0.0 2.1e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family MCU PF04678.13 EGB02878.1 - 0.00048 20.3 10.5 0.00063 19.9 10.5 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter LMBR1 PF04791.16 EGB02878.1 - 0.075 11.9 2.6 0.074 11.9 2.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Connexin PF00029.19 EGB02878.1 - 0.16 11.7 5.1 0.17 11.6 5.1 1.2 1 0 0 1 1 1 0 Connexin OATP PF03137.20 EGB02878.1 - 0.19 10.0 2.9 0.22 9.8 2.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.18 EGB02878.1 - 0.62 8.7 7.8 0.64 8.7 7.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.12 EGB02878.1 - 1.4 8.6 10.4 1.7 8.4 10.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.14 EGB02878.1 - 1.5 8.6 4.6 1.7 8.4 4.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Orf78 PF06024.12 EGB02878.1 - 2.2 8.6 4.7 4.2 7.7 4.7 1.7 1 1 0 1 1 1 0 Orf78 (ac78) CLN3 PF02487.17 EGB02878.1 - 4.1 6.3 8.5 4.6 6.2 8.5 1.1 1 0 0 1 1 1 0 CLN3 protein TFIIA PF03153.13 EGB02878.1 - 4.3 7.2 31.8 5.3 6.9 31.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 EGB02878.1 - 5.9 6.9 11.5 7.3 6.6 11.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 EGB02878.1 - 6 5.0 26.9 5.7 5.1 26.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIG-14_Wnt-bd PF06664.12 EGB02879.1 - 0.016 14.5 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion SecE PF00584.20 EGB02879.1 - 0.074 13.0 0.6 0.14 12.1 0.6 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sel1 PF08238.12 EGB02880.1 - 5.4e-21 74.6 10.0 1.6e-08 34.9 0.2 4.1 4 1 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 EGB02880.1 - 0.022 15.4 8.3 0.24 12.1 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB02880.1 - 0.38 11.1 4.4 1.5 9.1 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02880.1 - 1.4 9.2 12.9 0.37 11.0 0.5 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TRAPP PF04051.16 EGB02881.1 - 1.9e-36 125.0 0.0 2e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component IncFII_repA PF02387.15 EGB02881.1 - 0.061 12.6 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 IncFII RepA protein family KH_1 PF00013.29 EGB02882.1 - 1.6e-08 34.3 0.0 2.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 EGB02882.1 - 0.04 13.7 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 KH domain Glyco_transf_9 PF01075.17 EGB02882.1 - 0.17 11.2 0.2 0.31 10.3 0.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) SET PF00856.28 EGB02883.1 - 3.1e-16 60.2 0.1 4e-16 59.9 0.1 1.3 1 1 0 1 1 1 1 SET domain Ribosomal_L29 PF00831.23 EGB02885.1 - 1.5e-19 69.7 0.7 1.5e-19 69.7 0.7 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.19 EGB02885.1 - 0.16 12.5 8.2 0.25 11.9 8.2 1.3 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Prefoldin PF02996.17 EGB02885.1 - 1.4 8.9 6.6 2.6 8.0 0.8 2.6 3 0 0 3 3 3 0 Prefoldin subunit PAN_1 PF00024.26 EGB02887.1 - 0.2 11.7 4.3 0.44 10.5 4.3 1.6 1 1 0 1 1 1 0 PAN domain WD40 PF00400.32 EGB02889.1 - 2.1e-08 34.7 1.4 3.7e-06 27.6 0.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat PALP PF00291.25 EGB02891.1 - 8.9e-28 97.5 0.0 1e-27 97.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 60KD_IMP PF02096.20 EGB02892.1 - 6.5e-52 175.8 2.0 7.4e-52 175.6 2.0 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein HATPase_c PF02518.26 EGB02893.1 - 2e-24 86.3 0.0 3.2e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGB02893.1 - 4.3e-17 62.3 0.1 1.4e-16 60.7 0.1 1.9 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGB02893.1 - 9.5e-08 32.0 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SAP PF02037.27 EGB02893.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain Myb_DNA-binding PF00249.31 EGB02894.1 - 4.3e-15 55.6 0.2 1.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB02894.1 - 1e-14 54.5 0.1 6.4e-10 39.1 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain FKBP_C PF00254.28 EGB02895.1 - 1.1e-07 32.0 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4455 PF14643.6 EGB02895.1 - 0.051 12.2 0.7 0.069 11.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Adeno_E1B_19K PF01691.16 EGB02895.1 - 0.14 11.7 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Tropomyosin_1 PF12718.7 EGB02895.1 - 0.17 12.0 3.9 0.27 11.4 3.9 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF3486 PF11985.8 EGB02895.1 - 2.4 8.5 8.4 0.82 10.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) Na_H_Exchanger PF00999.21 EGB02896.1 - 5.4e-22 78.1 16.8 2.1e-21 76.1 16.8 1.7 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family FdhD-NarQ PF02634.15 EGB02896.1 - 0.11 12.2 2.0 0.18 11.5 2.0 1.3 1 0 0 1 1 1 0 FdhD/NarQ family Ion_trans PF00520.31 EGB02897.1 - 7.5e-10 38.4 9.7 8.4e-10 38.3 9.7 1.1 1 0 0 1 1 1 1 Ion transport protein GWT1 PF06423.12 EGB02897.1 - 0.63 10.1 3.6 0.56 10.3 2.1 1.6 1 1 0 1 1 1 0 GWT1 GST_N_3 PF13417.6 EGB02898.1 - 3.7e-12 46.5 0.0 1.3e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB02898.1 - 5.1e-09 36.3 0.0 8.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB02898.1 - 1.1e-06 28.5 0.9 2.7e-06 27.3 0.9 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB02898.1 - 5.9e-06 26.4 0.0 9.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGB02898.1 - 1.1e-05 25.5 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGB02898.1 - 0.00017 22.1 0.0 0.00028 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGB02898.1 - 0.0018 18.4 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 EGB02898.1 - 0.0073 17.0 0.0 0.04 14.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain DUF953 PF06110.11 EGB02898.1 - 0.11 12.1 0.2 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) FoP_duplication PF13865.6 EGB02899.1 - 0.016 15.8 0.4 0.016 15.8 0.4 2.5 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF4217 PF13959.6 EGB02900.1 - 6.9e-17 61.4 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF4148 PF13663.6 EGB02900.1 - 2 8.7 4.3 4 7.7 3.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4148) Malate_DH PF12434.8 EGB02900.1 - 6.7 6.8 12.5 2.9 8.0 6.5 2.7 1 1 1 2 2 2 0 Malate dehydrogenase enzyme Pkinase PF00069.25 EGB02901.1 - 2.2e-26 92.8 0.0 2.4e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02901.1 - 5e-12 45.6 0.0 5.8e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB02901.1 - 6.2e-05 23.0 2.8 0.003 17.5 2.8 3.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Myotub-related PF06602.14 EGB02902.1 - 1.2e-74 251.4 0.0 1.4e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGB02902.1 - 0.0075 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGB02902.1 - 0.0095 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGB02902.1 - 0.03 14.1 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2457 PF10446.9 EGB02903.1 - 0.18 10.9 4.6 0.27 10.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_L35p PF01632.19 EGB02903.1 - 0.28 11.7 4.4 13 6.4 0.4 2.5 2 0 0 2 2 2 0 Ribosomal protein L35 Sel1 PF08238.12 EGB02905.1 - 4.9e-21 74.7 9.0 1.5e-08 35.0 0.5 4.5 4 0 0 4 4 4 4 Sel1 repeat zf-MYND PF01753.18 EGB02905.1 - 1.7e-08 34.4 11.6 1.7e-08 34.4 11.6 2.7 3 0 0 3 3 3 1 MYND finger DUF1317 PF07026.11 EGB02905.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) TPR_1 PF00515.28 EGB02905.1 - 0.42 10.5 4.6 1.6 8.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4902 PF16245.5 EGB02906.1 - 0.025 14.5 0.7 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4902) Aldedh PF00171.22 EGB02907.1 - 5.6e-46 157.0 0.7 6.1e-46 156.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Form_Nir_trans PF01226.17 EGB02908.1 - 1.5e-31 109.6 7.6 1.9e-31 109.3 7.6 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF4199 PF13858.6 EGB02908.1 - 0.048 14.1 1.0 0.06 13.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RhodobacterPufX PF11511.8 EGB02908.1 - 0.37 10.4 0.1 0.37 10.4 0.1 1.9 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Methyltransf_23 PF13489.6 EGB02909.1 - 7.4e-09 35.7 0.0 8.7e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB02909.1 - 2.9e-08 34.3 0.0 3.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB02909.1 - 5.6e-07 30.2 0.0 8.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB02909.1 - 0.00015 22.4 0.0 0.00019 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02909.1 - 0.026 14.3 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase_4 PF12146.8 EGB02910.1 - 7.1e-06 25.5 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Polyketide_cyc2 PF10604.9 EGB02910.1 - 4.4e-05 23.8 1.8 0.00012 22.4 1.8 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Abhydrolase_3 PF07859.13 EGB02910.1 - 0.034 14.0 0.2 0.061 13.2 0.2 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB02910.1 - 0.22 12.1 17.8 0.023 15.3 10.1 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_M15 PF01427.17 EGB02911.1 - 0.042 13.6 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase TPR_19 PF14559.6 EGB02911.1 - 0.17 12.4 2.2 0.43 11.1 0.3 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat ABC_membrane PF00664.23 EGB02912.1 - 2.8e-32 112.5 10.6 4.1e-32 111.9 10.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB02912.1 - 6.5e-29 101.2 0.0 1.6e-28 100.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGB02912.1 - 0.00048 19.6 4.2 0.0057 16.1 4.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB02912.1 - 0.0063 16.3 0.7 0.054 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGB02912.1 - 0.07 13.4 3.8 0.15 12.3 0.5 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EGB02912.1 - 0.077 12.9 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EGB02912.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB02912.1 - 0.12 12.8 2.7 0.15 12.4 0.6 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EGB02912.1 - 0.12 11.9 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain MgtE PF01769.16 EGB02912.1 - 4 7.8 17.7 1.3 9.4 8.3 2.5 2 0 0 2 2 2 0 Divalent cation transporter ABC_tran PF00005.27 EGB02913.1 - 1.9e-27 96.5 0.0 2.5e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB02913.1 - 7.3e-05 22.7 2.5 0.00022 21.2 1.1 2.2 2 1 1 3 3 3 1 RsgA GTPase AAA_21 PF13304.6 EGB02913.1 - 8.5e-05 22.5 2.5 0.045 13.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB02913.1 - 8.9e-05 22.0 1.8 0.0027 17.2 1.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB02913.1 - 0.0015 18.2 2.7 0.0063 16.2 2.1 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB02913.1 - 0.0026 17.8 0.4 0.0051 16.9 0.4 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EGB02913.1 - 0.0056 16.4 0.1 0.0087 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB02913.1 - 0.0059 17.0 0.1 0.0083 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGB02913.1 - 0.0069 16.9 0.8 0.02 15.4 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB02913.1 - 0.0081 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB02913.1 - 0.028 14.7 0.2 0.046 14.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB02913.1 - 0.076 13.4 0.1 0.18 12.2 0.1 1.6 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 EGB02913.1 - 0.13 11.9 1.2 0.19 11.4 1.2 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 EGB02913.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EGB02913.1 - 0.18 11.5 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 EGB02913.1 - 0.18 11.9 2.5 0.32 11.0 2.5 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Tox-REase-5 PF15648.6 EGB02915.1 - 0.19 12.3 0.3 0.46 11.0 0.3 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 ProRS-C_1 PF09180.11 EGB02918.1 - 0.13 12.4 0.5 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal GFO_IDH_MocA PF01408.22 EGB02918.1 - 0.18 12.7 0.0 0.3 11.9 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Trypan_PARP PF05887.11 EGB02919.1 - 0.00038 20.4 28.6 0.00038 20.4 28.6 2.3 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) SHOCT PF09851.9 EGB02919.1 - 0.0027 17.4 0.0 0.011 15.5 0.0 2.2 1 0 0 1 1 1 1 Short C-terminal domain WDCP PF15390.6 EGB02919.1 - 1.8 6.8 8.0 2.7 6.2 8.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family XRN_N PF03159.18 EGB02919.1 - 8.3 5.8 8.1 20 4.5 8.1 1.6 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Ribosomal_L14e PF01929.17 EGB02920.1 - 0.43 11.1 2.0 0.96 10.0 2.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L14 DNA_methylase PF00145.17 EGB02921.1 - 0.0013 18.1 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF4116 PF13475.6 EGB02923.1 - 1.4e-13 50.3 0.0 2.1e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4116) Ank_5 PF13857.6 EGB02924.1 - 0.00014 22.1 0.4 0.14 12.5 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB02924.1 - 0.00024 21.3 0.0 0.037 14.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGB02924.1 - 0.00029 21.4 0.0 0.015 15.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB02924.1 - 0.0021 18.6 0.1 0.11 13.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGB02924.1 - 0.019 15.4 0.2 0.37 11.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Patatin PF01734.22 EGB02925.1 - 6.3e-28 98.3 0.6 1.2e-27 97.4 0.6 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase IDO PF01231.18 EGB02925.1 - 5.9e-15 55.0 0.0 1.3e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase Rab5ip PF07019.12 EGB02925.1 - 0.14 12.7 0.1 0.31 11.6 0.1 1.6 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Methyltransf_21 PF05050.12 EGB02926.1 - 0.00011 22.2 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_24 PF13578.6 EGB02928.1 - 0.00022 22.2 1.3 0.00042 21.3 0.2 2.0 2 1 0 2 2 2 1 Methyltransferase domain DUF1325 PF07039.11 EGB02929.1 - 7.9e-06 26.0 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EGB02929.1 - 4.7e-05 23.2 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4091 PF13320.6 EGB02929.1 - 0.0022 18.1 0.5 4.4 7.5 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4091) DUF4537 PF15057.6 EGB02929.1 - 0.0038 17.2 0.1 0.009 16.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Agenet PF05641.12 EGB02929.1 - 0.038 14.5 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Agenet domain Tudor_2 PF18104.1 EGB02929.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Peptidase_M16_C PF05193.21 EGB02930.1 - 0.00023 21.2 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain MCR_gamma PF02240.16 EGB02930.1 - 0.094 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit HEAT PF02985.22 EGB02930.1 - 2.9 8.4 4.8 6.3 7.3 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat TPR_12 PF13424.6 EGB02931.1 - 2.8e-100 328.7 70.6 3.5e-19 68.9 6.2 7.2 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGB02931.1 - 1e-72 238.2 46.0 5.5e-11 42.0 0.0 8.3 9 0 0 9 9 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 EGB02931.1 - 6.3e-44 144.8 34.6 3.6e-08 32.9 0.9 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02931.1 - 1.4e-34 115.3 24.2 6.5e-05 22.8 0.4 7.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02931.1 - 3e-33 112.3 25.0 3.5e-06 26.6 0.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGB02931.1 - 1.8e-28 96.3 32.2 7.5e-06 25.7 0.1 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_4 PF07721.14 EGB02931.1 - 3.2e-17 61.3 9.7 0.004 17.6 0.0 8.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02931.1 - 1.1e-14 54.0 18.9 0.016 15.8 0.3 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02931.1 - 2.8e-14 52.6 31.8 0.0042 17.8 0.3 8.0 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_5 PF12688.7 EGB02931.1 - 9.1e-11 42.0 14.5 0.0068 16.7 0.0 6.0 1 1 5 6 6 6 4 Tetratrico peptide repeat TPR_11 PF13414.6 EGB02931.1 - 1.8e-09 37.1 28.0 0.011 15.4 0.9 7.3 7 0 0 7 7 7 4 TPR repeat TPR_17 PF13431.6 EGB02931.1 - 6.7e-09 35.5 15.0 1.9 9.0 0.2 8.3 7 3 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB02931.1 - 3.9e-08 33.8 37.9 0.006 17.2 3.9 6.3 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB02931.1 - 1.9e-07 30.8 8.5 7.4e-06 25.6 1.3 2.2 1 1 1 2 2 2 2 MalT-like TPR region DUF1955 PF09205.10 EGB02931.1 - 9.6e-07 28.7 0.9 17 5.1 0.0 6.4 1 1 6 7 7 7 0 Domain of unknown function (DUF1955) DUF4807 PF16065.5 EGB02931.1 - 1.3e-06 28.1 4.0 12 5.6 0.0 6.6 3 2 3 7 7 7 0 Domain of unknown function (DUF4807) Mob_Pre PF01076.19 EGB02931.1 - 1.4e-05 25.0 0.5 4.6 7.0 0.0 5.7 3 3 3 7 7 7 1 Plasmid recombination enzyme SPO22 PF08631.10 EGB02931.1 - 0.00019 21.0 0.2 1.7 8.0 0.0 3.1 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like DUF2225 PF09986.9 EGB02931.1 - 0.0011 18.8 1.7 0.1 12.3 0.0 3.3 1 1 3 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.6 EGB02931.1 - 0.0016 17.9 1.3 0.0016 17.9 1.3 2.0 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 EGB02931.1 - 0.0019 18.2 16.5 1.9 8.6 0.1 6.0 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 EGB02931.1 - 0.0062 16.3 5.0 0.53 10.0 0.3 3.5 1 1 1 3 3 3 1 26S proteasome subunit RPN7 Foie-gras_1 PF11817.8 EGB02931.1 - 0.016 14.8 1.1 0.12 12.0 0.3 2.4 1 1 0 2 2 2 0 Foie gras liver health family 1 Tcf25 PF04910.14 EGB02931.1 - 0.025 13.7 0.5 13 4.7 0.0 3.9 3 1 3 6 6 6 0 Transcriptional repressor TCF25 PPR PF01535.20 EGB02931.1 - 0.032 14.5 4.1 9.5 6.7 0.0 5.3 6 0 0 6 6 6 0 PPR repeat pKID PF02173.17 EGB02931.1 - 0.032 13.7 4.3 21 4.7 0.0 5.1 6 0 0 6 6 6 0 pKID domain SMBP PF16785.5 EGB02931.1 - 0.036 14.3 4.2 1.1 9.5 0.5 3.1 2 1 0 3 3 3 0 Small metal-binding protein Sel1 PF08238.12 EGB02931.1 - 0.045 14.4 9.1 59 4.5 0.0 5.6 5 0 0 5 5 5 0 Sel1 repeat DUF627 PF04781.12 EGB02931.1 - 0.055 13.5 4.3 19 5.3 0.0 4.9 3 2 1 5 5 5 0 Protein of unknown function (DUF627) DUF1501 PF07394.12 EGB02931.1 - 0.096 11.7 1.4 6.2 5.8 0.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1501) MIT PF04212.18 EGB02931.1 - 0.18 11.9 6.9 0.37 10.9 0.5 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EGB02931.1 - 0.25 11.4 1.0 2.4 8.3 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGB02931.1 - 0.28 11.2 10.0 0.2 11.7 1.5 3.8 1 1 4 5 5 5 0 Domain of Unknown Function (DUF3856) DUF5113 PF17140.4 EGB02931.1 - 2 8.2 4.6 3.1 7.6 0.3 3.2 3 2 1 4 4 4 0 Domain of unknown function (DUF5113) Sulfotransfer_2 PF03567.14 EGB02932.1 - 0.0019 18.1 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family EPSP_synthase PF00275.20 EGB02932.1 - 0.076 11.7 0.3 0.12 11.0 0.3 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SH3_3 PF08239.11 EGB02933.1 - 1.6e-08 34.7 0.3 1.4e-05 25.3 0.2 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain HMG_box PF00505.19 EGB02933.1 - 3.8e-05 24.0 2.2 8.7e-05 22.9 2.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box SH3_4 PF06347.13 EGB02933.1 - 0.00019 21.2 1.3 0.00059 19.6 0.8 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain HMG_box_2 PF09011.10 EGB02933.1 - 0.19 12.4 3.2 0.42 11.2 3.2 1.6 1 0 0 1 1 1 0 HMG-box domain PRIMA1 PF16101.5 EGB02933.1 - 0.2 11.7 6.3 1.5 8.9 0.7 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PAP_fibrillin PF04755.12 EGB02934.1 - 6.9e-05 22.9 0.3 0.0095 15.9 0.0 3.2 3 1 0 3 3 3 1 PAP_fibrillin DUF2046 PF09755.9 EGB02934.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) TMF_DNA_bd PF12329.8 EGB02934.1 - 2.9 7.9 7.9 5.4 7.1 0.2 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TNFR_c6 PF00020.18 EGB02935.1 - 2e-06 28.1 14.8 3.1e-05 24.3 6.0 5.4 3 1 3 6 6 6 4 TNFR/NGFR cysteine-rich region PT PF04886.12 EGB02936.1 - 0.0002 20.8 34.2 0.052 13.1 13.1 2.5 2 0 0 2 2 2 2 PT repeat DinB_2 PF12867.7 EGB02936.1 - 0.00032 21.2 0.0 1.7 9.2 0.0 2.7 3 0 0 3 3 2 2 DinB superfamily bZIP_2 PF07716.15 EGB02936.1 - 0.028 14.5 2.3 7.4 6.7 0.2 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF4148 PF13663.6 EGB02936.1 - 0.053 13.7 3.0 21 5.4 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) KCNQ2_u3 PF16642.5 EGB02936.1 - 0.13 13.3 12.4 7.9 7.5 1.5 3.6 3 0 0 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DUF2570 PF10828.8 EGB02936.1 - 0.22 11.3 2.4 5.7 6.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) BMFP PF04380.13 EGB02936.1 - 0.68 10.5 7.5 9.7 6.8 0.9 2.6 2 0 0 2 2 2 0 Membrane fusogenic activity Ax_dynein_light PF10211.9 EGB02936.1 - 0.89 9.5 14.0 24 4.8 1.1 4.3 4 0 0 4 4 4 0 Axonemal dynein light chain ARGLU PF15346.6 EGB02936.1 - 1.2 9.0 12.6 2 8.3 0.2 2.7 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 Acyl-CoA_dh_2 PF08028.11 EGB02936.1 - 1.4 9.1 5.5 31 4.8 0.5 3.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain SWIRM-assoc_1 PF16495.5 EGB02936.1 - 1.8 8.6 9.2 3.5 7.7 1.1 2.5 2 0 0 2 2 2 0 SWIRM-associated region 1 Peptidase_S49_N PF08496.10 EGB02936.1 - 2.5 8.2 6.3 18 5.3 0.8 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Fez1 PF06818.15 EGB02936.1 - 3.8 7.9 10.9 1.9 8.9 0.2 3.0 3 0 0 3 3 3 0 Fez1 Cgr1 PF03879.14 EGB02936.1 - 5.3 7.5 12.0 7.9 6.9 1.1 2.9 2 0 0 2 2 2 0 Cgr1 family KfrA_N PF11740.8 EGB02936.1 - 8.2 7.1 19.2 25 5.6 2.2 4.5 4 0 0 4 4 4 0 Plasmid replication region DNA-binding N-term SKA1 PF07160.12 EGB02936.1 - 9.7 6.0 11.2 15 5.3 0.0 4.1 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 1 Mpv17_PMP22 PF04117.12 EGB02938.1 - 0.0059 16.8 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4778 PF16008.5 EGB02938.1 - 3.6 7.6 15.9 6.6 6.7 7.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4778) Alkyl_sulf_C PF14864.6 EGB02938.1 - 4.6 7.5 8.0 19 5.6 1.9 3.2 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal HATPase_c PF02518.26 EGB02939.1 - 7.2e-08 32.9 0.1 1.7e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGB02939.1 - 6e-05 22.9 0.0 8.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MpPF1 PF07668.11 EGB02939.1 - 0.059 12.6 0.0 0.065 12.5 0.0 1.0 1 0 0 1 1 1 0 M penetrans paralogue family 1 DUF5634 PF18681.1 EGB02939.1 - 0.13 12.6 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5634) Na_H_Exchanger PF00999.21 EGB02940.1 - 1.4e-14 53.7 22.9 2.1e-14 53.1 22.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TPR_2 PF07719.17 EGB02941.1 - 0.25 11.6 11.4 3.4 8.0 1.6 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGB02942.1 - 7.8e-12 45.6 0.0 7.1e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB02942.1 - 1.8e-09 37.9 0.2 0.0041 17.7 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB02942.1 - 3.1e-09 36.9 0.0 0.0062 16.9 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB02942.1 - 1.1e-08 34.6 0.0 0.0035 17.7 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeat Methyltransf_21 PF05050.12 EGB02942.1 - 4.4e-08 33.3 0.0 8.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Ank_5 PF13857.6 EGB02942.1 - 9.4e-05 22.6 2.6 0.65 10.4 0.0 4.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Cupin_2 PF07883.11 EGB02942.1 - 0.00087 19.0 0.1 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 EGB02942.1 - 0.005 17.3 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 EGB02942.1 - 0.0099 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EGB02942.1 - 0.085 12.8 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain Na_Ca_ex PF01699.24 EGB02943.1 - 3.4e-22 79.0 5.7 4.1e-22 78.8 5.7 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Methyltr_RsmB-F PF01189.17 EGB02944.1 - 5.2e-33 114.4 0.0 1e-32 113.5 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 EGB02944.1 - 1.3e-05 25.8 0.2 0.00015 22.4 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.19 EGB02944.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 EGB02944.1 - 0.0073 16.9 0.1 0.047 14.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB02944.1 - 0.0073 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Mersacidin PF16934.5 EGB02944.1 - 1.9 8.3 4.7 6.9 6.5 0.9 2.9 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) E1-E2_ATPase PF00122.20 EGB02945.1 - 1.4e-13 50.7 1.0 4.4e-13 49.1 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EGB02945.1 - 7.3e-11 41.6 0.0 1.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGB02946.1 - 6.5e-05 22.8 0.9 6.9e-05 22.7 0.9 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB02946.1 - 0.0064 16.8 0.3 0.0083 16.4 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EGB02947.1 - 1.3e-52 178.8 0.0 1.4e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02947.1 - 3.4e-30 105.2 0.0 3.9e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB02947.1 - 0.0018 17.1 0.0 0.0025 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB02947.1 - 0.0056 16.1 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB02947.1 - 0.0068 15.8 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGB02947.1 - 0.063 12.8 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TPR_2 PF07719.17 EGB02948.1 - 2.3e-07 30.4 13.9 0.0039 17.2 2.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGB02948.1 - 1.2e-06 28.5 9.3 4.6e-06 26.7 9.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB02948.1 - 1.3e-06 28.0 9.4 0.012 15.4 1.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB02948.1 - 0.00084 19.6 13.0 0.1 12.9 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB02948.1 - 0.19 12.0 1.1 0.95 9.8 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB02948.1 - 1.7 9.7 15.1 1.5 9.8 4.1 4.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB02948.1 - 2.7 8.8 6.5 0.88 10.3 0.9 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Phage_TAC_1 PF06222.11 EGB02949.1 - 0.13 12.0 0.0 8.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone Hus1 PF04005.12 EGB02950.1 - 0.0096 15.1 0.0 0.011 14.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Pkinase PF00069.25 EGB02951.1 - 3.1e-42 144.8 0.0 4.6e-42 144.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02951.1 - 6.3e-18 65.0 0.0 1.5e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB02951.1 - 0.00056 19.0 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB02951.1 - 0.0039 17.1 5.6 0.011 15.6 1.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB02951.1 - 0.024 14.0 0.1 0.2 11.0 0.0 2.0 1 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 EGB02951.1 - 0.14 11.5 0.2 0.24 10.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGB02951.1 - 0.17 11.4 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Hydrolase PF00702.26 EGB02952.1 - 8.4e-31 107.9 4.1 8.6e-31 107.9 2.7 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGB02952.1 - 1.7e-16 60.4 0.0 8.4e-07 29.3 0.2 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 EGB02952.1 - 1.5e-14 54.0 0.1 1.5e-14 54.0 0.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGB02952.1 - 0.0069 16.2 0.9 0.013 15.2 0.9 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB02952.1 - 0.05 14.0 0.9 0.38 11.1 0.1 2.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase TusA PF01206.17 EGB02952.1 - 0.22 11.4 0.3 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Sulfurtransferase TusA PP2C PF00481.21 EGB02953.1 - 1e-26 94.1 0.0 1.3e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB02953.1 - 3.2e-05 23.7 0.1 5.1e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C ketoacyl-synt PF00109.26 EGB02954.1 - 5.5e-25 88.4 3.6 6.4e-25 88.2 3.6 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB02955.1 - 2.7e-14 53.2 1.8 2.9e-14 53.1 1.8 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Ketoacyl-synt_C PF02801.22 EGB02956.1 - 2.2e-14 53.5 0.7 4.1e-14 52.6 0.7 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Kinocilin PF15033.6 EGB02956.1 - 0.14 11.8 2.1 0.17 11.6 1.6 1.6 1 1 0 1 1 1 0 Kinocilin protein SIR2 PF02146.17 EGB02957.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.6 1 1 1 2 2 2 0 Sir2 family Peptidase_M24 PF00557.24 EGB02960.1 - 2e-50 171.4 0.3 3.2e-50 170.7 0.3 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Fer4_13 PF13370.6 EGB02960.1 - 1.1e-13 51.4 2.9 6.5e-13 49.0 2.9 2.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I WD40 PF00400.32 EGB02960.1 - 1.3e-12 48.0 14.1 0.0006 20.6 0.1 4.9 3 1 1 4 4 4 4 WD domain, G-beta repeat Fer4_15 PF13459.6 EGB02960.1 - 2.6e-08 34.5 1.9 2.6e-08 34.5 1.9 4.1 4 0 0 4 4 4 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 EGB02960.1 - 0.014 15.4 0.4 0.052 13.6 0.4 2.0 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_20 PF14691.6 EGB02960.1 - 0.13 12.0 4.5 5.8 6.7 0.2 2.6 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster YesK PF14150.6 EGB02960.1 - 0.19 11.9 0.2 0.46 10.7 0.2 1.5 1 0 0 1 1 1 0 YesK-like protein Fer4_10 PF13237.6 EGB02960.1 - 5.1 7.3 16.9 0.067 13.3 1.1 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain ArfGap PF01412.18 EGB02961.1 - 1.9e-23 82.8 0.9 2e-23 82.7 0.9 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zinc-ribbons_6 PF07191.12 EGB02961.1 - 0.019 14.9 1.0 0.027 14.4 1.0 1.3 1 0 0 1 1 1 0 zinc-ribbons 2-Hacid_dh_C PF02826.19 EGB02962.1 - 6.7e-34 116.8 0.0 1.2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGB02962.1 - 7.4e-15 54.8 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGB02962.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EGB02962.1 - 0.0044 16.6 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EGB02962.1 - 0.057 13.3 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGB02962.1 - 0.084 13.5 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Acyl-CoA_dh_1 PF00441.24 EGB02963.1 - 0.0017 18.6 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.32 EGB02964.1 - 0.00023 21.9 11.5 4.7 8.2 0.3 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat CMS1 PF14617.6 EGB02964.1 - 0.22 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF4081 PF13312.6 EGB02964.1 - 7.1 6.9 10.1 0.87 9.8 1.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4081) Na_Ca_ex PF01699.24 EGB02965.1 - 2.2e-26 92.6 7.5 2.6e-26 92.4 7.5 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Neurensin PF14927.6 EGB02965.1 - 0.15 11.8 2.6 0.92 9.2 0.3 2.1 2 0 0 2 2 2 0 Neurensin DUF3040 PF11239.8 EGB02965.1 - 1.9 8.8 4.9 6 7.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Tyrosinase PF00264.20 EGB02966.1 - 3.7e-08 33.9 0.2 5.6e-05 23.5 0.0 2.8 2 1 0 2 2 2 2 Common central domain of tyrosinase Cwf_Cwc_15 PF04889.12 EGB02966.1 - 0.14 11.8 11.1 0.3 10.8 11.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1177 PF06675.11 EGB02966.1 - 0.23 10.3 0.1 0.44 9.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) SDA1 PF05285.12 EGB02966.1 - 0.24 10.8 5.3 0.36 10.2 5.3 1.1 1 0 0 1 1 1 0 SDA1 GEN1_C PF18380.1 EGB02966.1 - 0.41 11.6 1.3 0.94 10.4 1.3 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Nop14 PF04147.12 EGB02966.1 - 2 6.5 6.5 2.8 6.0 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family zf-AN1 PF01428.16 EGB02966.1 - 8 6.7 8.2 6.5 7.0 4.6 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger DNA_pol_phi PF04931.13 EGB02966.1 - 8.3 4.4 15.5 15 3.5 15.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Prenyltransf PF01255.19 EGB02967.1 - 9.2e-65 218.3 0.0 1e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Herpes_US12 PF05363.12 EGB02967.1 - 0.095 13.4 0.7 0.43 11.3 0.3 2.2 1 1 1 2 2 2 0 Herpesvirus US12 family PCRF PF03462.18 EGB02968.1 - 4.3e-41 140.9 0.0 1.1e-40 139.6 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EGB02968.1 - 6.8e-31 106.6 3.2 9e-24 83.6 1.5 2.5 2 1 1 3 3 3 2 RF-1 domain MIR PF02815.19 EGB02968.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 MIR domain Tex_N PF09371.10 EGB02969.1 - 2.3e-22 79.6 0.5 5e-22 78.4 0.5 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 EGB02969.1 - 4.3e-17 62.8 0.2 4.6e-15 56.2 0.2 2.4 1 1 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 EGB02969.1 - 1.4e-16 60.5 0.0 3.1e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 EGB02969.1 - 2.8e-10 40.4 0.2 5.6e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 S1 RNA binding domain TPR_17 PF13431.6 EGB02969.1 - 1.2e-07 31.5 0.5 0.47 11.0 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat HHH_9 PF17674.1 EGB02969.1 - 4.9e-06 27.4 0.0 1.7e-05 25.7 0.0 2.0 1 0 0 1 1 1 1 HHH domain HHH PF00633.23 EGB02969.1 - 0.00044 20.0 0.8 0.21 11.5 0.0 3.6 3 0 0 3 3 3 1 Helix-hairpin-helix motif TPR_16 PF13432.6 EGB02969.1 - 0.0018 18.8 1.5 0.0018 18.8 1.5 10.0 6 5 3 9 9 6 3 Tetratricopeptide repeat HHH_5 PF14520.6 EGB02969.1 - 0.0043 17.6 4.9 1.7 9.3 2.7 3.2 3 0 0 3 3 2 2 Helix-hairpin-helix domain TPR_20 PF14561.6 EGB02969.1 - 0.041 14.2 0.5 0.041 14.2 0.5 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat PsbU PF06514.11 EGB02969.1 - 0.045 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) YqgF PF14639.6 EGB02969.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 EGB02969.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif TPR_10 PF13374.6 EGB02969.1 - 3.8 7.5 9.1 0.35 10.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HIT PF01230.23 EGB02970.1 - 6.4e-14 52.5 0.0 7.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGB02970.1 - 0.035 14.6 0.0 0.045 14.2 0.0 1.1 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Pkinase PF00069.25 EGB02971.1 - 9.5e-58 195.6 0.0 1.1e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02971.1 - 3.2e-27 95.5 0.0 3.8e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB02971.1 - 0.0099 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGB02971.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF659 PF04937.15 EGB02972.1 - 2.1e-05 24.4 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FYVE_2 PF02318.16 EGB02973.1 - 0.016 15.4 1.1 0.016 15.4 1.1 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger DNA_pol_phi PF04931.13 EGB02973.1 - 1.3 7.0 11.8 5.4 5.0 7.7 2.2 2 0 0 2 2 2 0 DNA polymerase phi Arylsulfotrans PF05935.11 EGB02974.1 - 6.2e-06 25.4 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB02974.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Peptidase_M24 PF00557.24 EGB02975.1 - 2.8e-52 177.5 0.1 3.7e-52 177.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGB02975.1 - 4.3e-23 81.4 0.0 9.8e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain adh_short PF00106.25 EGB02976.1 - 8.9e-17 61.2 0.8 2.9e-15 56.2 0.2 2.6 3 0 0 3 3 3 1 short chain dehydrogenase TTL PF03133.15 EGB02976.1 - 8.6e-14 51.3 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family adh_short_C2 PF13561.6 EGB02976.1 - 6.2e-05 22.7 3.7 0.00015 21.4 3.7 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB02976.1 - 0.0078 16.1 0.8 0.018 15.0 0.8 1.5 1 0 0 1 1 1 1 KR domain Response_reg PF00072.24 EGB02977.1 - 7e-21 74.5 0.0 8.2e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain CRAL_TRIO PF00650.20 EGB02979.1 - 1.1e-10 41.5 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain SEC-C PF02810.15 EGB02980.1 - 6.4 6.8 11.0 2.6 8.1 0.8 2.9 3 0 0 3 3 3 0 SEC-C motif Peptidase_C1 PF00112.23 EGB02981.1 - 8.6e-42 143.7 0.0 9.3e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB02981.1 - 0.0072 15.2 0.0 0.034 12.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase C1-like family Ysc84 PF04366.12 EGB02982.1 - 5.2e-30 103.8 1.0 9.1e-30 103.0 0.9 1.4 2 0 0 2 2 2 1 Las17-binding protein actin regulator WD40 PF00400.32 EGB02983.1 - 3.5e-73 239.7 30.7 4.9e-10 39.8 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB02983.1 - 2.3e-21 75.9 2.7 0.02 15.2 0.0 6.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB02983.1 - 3.1e-14 52.5 2.4 0.45 9.1 0.1 6.0 3 2 3 6 6 6 6 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGB02983.1 - 2.2e-10 40.5 21.7 4.2e-05 23.2 4.7 3.5 1 1 3 4 4 4 4 PQQ-like domain PQQ PF01011.21 EGB02983.1 - 7.4e-09 35.1 0.1 10 6.3 0.0 6.1 6 0 0 6 6 6 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 EGB02983.1 - 1.1e-07 30.7 3.2 0.006 15.2 0.1 2.5 1 1 2 3 3 3 3 Cytochrome D1 heme domain WD40_like PF17005.5 EGB02983.1 - 4.2e-06 26.3 0.0 0.22 10.8 0.0 3.9 3 1 1 4 4 4 1 WD40-like domain Surfac_D-trimer PF09006.11 EGB02983.1 - 0.00018 21.3 4.5 1.4e+02 2.5 0.0 6.8 7 0 0 7 7 7 0 Lung surfactant protein D coiled-coil trimerisation DUF1652 PF07865.11 EGB02983.1 - 0.00019 21.2 0.3 71 3.3 0.0 5.7 5 1 1 6 6 6 0 Protein of unknown function (DUF1652) FlaG PF03646.15 EGB02983.1 - 0.00027 21.1 0.8 93 3.3 0.0 5.6 6 0 0 6 6 6 0 FlaG protein PQQ_3 PF13570.6 EGB02983.1 - 0.00028 21.3 26.8 0.35 11.4 0.5 6.5 7 0 0 7 7 7 2 PQQ-like domain Ge1_WD40 PF16529.5 EGB02983.1 - 0.00029 19.9 8.6 0.32 9.9 1.0 4.9 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cuticle_4 PF15955.5 EGB02983.1 - 0.00047 20.8 0.4 14 6.4 0.1 5.0 5 1 0 6 6 5 0 Cuticle protein DUF5570 PF17731.1 EGB02983.1 - 0.0011 19.1 26.5 0.16 12.1 1.0 5.2 1 1 5 6 6 6 4 Family of unknown function (DUF5570) Frtz PF11768.8 EGB02983.1 - 0.0012 17.3 0.0 2.1 6.5 0.0 2.9 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EGB02983.1 - 0.0013 17.7 18.2 0.29 10.0 0.3 5.5 1 1 4 6 6 6 4 Partner and localizer of BRCA2 WD40 domain MTH865 PF07747.11 EGB02983.1 - 0.013 15.3 0.0 2.6e+02 1.5 0.0 5.3 6 0 0 6 6 6 0 MTH865-like family CNH PF00780.22 EGB02983.1 - 0.13 11.8 0.0 82 2.7 0.0 4.3 5 1 1 6 6 6 0 CNH domain DUF4405 PF14358.6 EGB02983.1 - 0.16 12.5 1.0 19 5.9 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) DUF2222 PF09984.9 EGB02983.1 - 0.21 11.4 0.0 1.5e+02 2.2 0.0 4.2 5 0 0 5 5 5 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) TruB_C PF09142.11 EGB02983.1 - 0.23 11.3 16.9 13 5.6 0.3 6.1 5 1 1 6 6 6 0 tRNA Pseudouridine synthase II, C terminal Ribosomal_S17 PF00366.20 EGB02983.1 - 2 8.6 12.9 47 4.2 0.1 5.8 7 0 0 7 7 7 0 Ribosomal protein S17 BAT PF15915.5 EGB02983.1 - 4.7 7.1 19.0 6.3 6.7 0.4 4.6 1 1 4 5 5 5 0 GAF and HTH_10 associated domain p450 PF00067.22 EGB02984.1 - 1.5e-31 109.6 0.0 8.4e-31 107.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Thioredoxin PF00085.20 EGB02985.1 - 6.5e-15 55.0 0.1 7e-15 54.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGB02985.1 - 0.0091 15.9 0.0 0.011 15.6 0.0 1.2 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGB02985.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin-like Redoxin PF08534.10 EGB02985.1 - 0.051 13.3 0.1 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.6 EGB02985.1 - 0.11 12.9 0.1 0.46 11.0 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Acyltransferase PF01553.21 EGB02986.1 - 1.2e-27 96.1 0.0 1.6e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase EF-hand_7 PF13499.6 EGB02987.1 - 1.3e-05 25.6 0.1 3.5e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB02987.1 - 7e-05 22.4 0.3 0.55 10.3 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGB02987.1 - 0.00018 20.8 1.2 1.2 8.8 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGB02987.1 - 0.00056 19.7 0.9 0.11 12.4 0.1 3.1 4 0 0 4 4 4 2 EF-hand domain pair PRTP PF01366.18 EGB02987.1 - 0.62 8.0 2.6 0.77 7.7 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein TPMT PF05724.11 EGB02988.1 - 4.8e-43 147.3 0.0 5.7e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EGB02988.1 - 0.047 14.4 0.0 0.16 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PseudoU_synth_2 PF00849.22 EGB02989.1 - 1.2e-14 54.7 0.0 2.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EGB02989.1 - 5e-08 32.5 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain His_Phos_1 PF00300.22 EGB02990.1 - 2.3e-31 109.0 0.5 3.2e-20 72.6 0.2 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 EGB02991.1 - 9.1e-12 44.9 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB02991.1 - 4.3e-08 32.8 0.0 5.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3482 PF11981.8 EGB02991.1 - 0.53 9.6 6.4 0.062 12.7 1.8 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3482) Aldedh PF00171.22 EGB02993.1 - 9e-06 24.4 5.5 0.0031 16.1 3.7 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LRR_4 PF12799.7 EGB02994.1 - 6e-11 42.4 1.5 0.068 13.6 0.0 4.9 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB02994.1 - 5.5e-09 35.7 2.4 0.0056 16.4 0.7 3.7 3 1 0 3 3 3 3 Leucine rich repeat NACHT PF05729.12 EGB02994.1 - 3.9e-06 26.9 0.0 1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.6 EGB02994.1 - 0.16 12.1 1.1 12 6.2 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EGB02994.1 - 8.3 7.4 9.2 13 6.8 0.0 5.0 5 2 0 5 5 5 0 Leucine Rich Repeat WD40 PF00400.32 EGB02995.1 - 4.6e-68 223.5 26.9 8e-11 42.3 0.1 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB02995.1 - 1.5e-20 73.2 3.3 0.005 17.1 0.0 6.4 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB02995.1 - 8.8e-08 31.2 7.0 0.9 8.1 0.0 6.2 3 2 3 7 7 7 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGB02995.1 - 3.3e-07 30.1 22.0 0.011 15.4 6.9 3.9 1 1 2 3 3 3 3 PQQ-like domain PD40 PF07676.12 EGB02995.1 - 2.4e-05 24.2 0.0 28 4.8 0.0 6.6 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 EGB02995.1 - 0.00014 21.6 0.2 33 4.6 0.0 5.3 6 0 0 6 6 5 0 PQQ enzyme repeat Me-amine-dh_H PF06433.11 EGB02995.1 - 0.00032 19.7 0.1 0.23 10.3 0.0 3.2 2 1 2 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) Surfac_D-trimer PF09006.11 EGB02995.1 - 0.0004 20.2 1.8 1.1e+02 2.8 0.0 6.1 6 0 0 6 6 6 0 Lung surfactant protein D coiled-coil trimerisation DUF1652 PF07865.11 EGB02995.1 - 0.00075 19.3 0.5 61 3.5 0.0 6.1 7 0 0 7 7 7 0 Protein of unknown function (DUF1652) BRK PF07533.16 EGB02995.1 - 0.0059 16.2 0.0 42 3.9 0.0 4.8 6 0 0 6 6 6 0 BRK domain PALB2_WD40 PF16756.5 EGB02995.1 - 0.013 14.5 16.2 2.5 7.0 0.2 5.4 3 2 3 6 6 6 0 Partner and localizer of BRCA2 WD40 domain CDtoxinA PF03498.14 EGB02995.1 - 0.028 14.0 0.1 30 4.2 0.1 4.2 3 2 1 4 4 4 0 Cytolethal distending toxin A/C domain Prot_ATP_ID_OB PF16450.5 EGB02995.1 - 0.041 13.8 6.1 37 4.4 0.0 5.3 6 0 0 6 6 6 0 Proteasomal ATPase OB C-terminal domain Ge1_WD40 PF16529.5 EGB02995.1 - 0.09 11.7 6.7 3.9 6.3 0.1 4.4 1 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGB02995.1 - 0.22 10.8 0.0 9.7 5.4 0.0 2.7 3 1 0 3 3 3 0 WD40-like domain CbiG_N PF11760.8 EGB02995.1 - 0.54 10.3 13.3 1.8 8.6 0.0 4.8 5 1 1 6 6 6 0 Cobalamin synthesis G N-terminal IMP2_C PF18591.1 EGB02995.1 - 0.6 10.0 3.0 10 6.0 0.0 3.9 4 0 0 4 4 4 0 Immune Mapped Protein 2 (IMP2) C-terminal domain DUF5570 PF17731.1 EGB02995.1 - 4.2 7.5 17.8 2.6 8.2 0.3 5.1 1 1 2 5 5 5 0 Family of unknown function (DUF5570) PQQ_3 PF13570.6 EGB02995.1 - 8 7.1 15.1 60 4.3 0.3 5.3 5 0 0 5 5 5 0 PQQ-like domain EF-hand_1 PF00036.32 EGB02996.1 - 1.9e-11 42.6 0.4 1.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB02996.1 - 2.2e-10 39.6 0.4 1.4e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB02996.1 - 2.6e-09 36.1 0.4 2.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB02996.1 - 5.7e-09 36.3 0.1 6.3e-09 36.2 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB02996.1 - 1.1e-06 28.4 1.2 0.00098 18.9 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair Mito_carr PF00153.27 EGB02997.1 - 2.2e-22 78.8 1.4 5.8e-16 58.2 0.4 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Fe_hyd_lg_C PF02906.14 EGB02997.1 - 0.09 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain AMP-binding PF00501.28 EGB02998.1 - 5.5e-23 81.2 0.0 6.9e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Trypsin_2 PF13365.6 EGB02999.1 - 1.3e-15 58.6 0.2 1.9e-15 58.1 0.2 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGB02999.1 - 0.0015 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S39 PF02122.15 EGB02999.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 Sulfatase PF00884.23 EGB03000.1 - 2.8e-14 53.2 0.2 3.3e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 Sulfatase 2_5_RNA_ligase2 PF13563.6 EGB03001.1 - 0.031 14.2 0.0 0.089 12.7 0.0 1.8 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily 14-3-3 PF00244.20 EGB03002.1 - 1.4e-97 325.5 0.1 1.7e-97 325.3 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 EGB03002.1 - 0.21 12.1 2.5 0.5 10.9 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3450 PF11932.8 EGB03004.1 - 0.0038 16.6 6.2 0.0038 16.6 6.2 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) HALZ PF02183.18 EGB03004.1 - 0.006 16.8 0.8 0.018 15.2 0.8 1.9 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF2856 PF11043.8 EGB03004.1 - 0.066 13.3 1.6 0.085 13.0 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2856) DASH_Spc34 PF08657.10 EGB03004.1 - 0.58 9.9 10.0 0.73 9.6 8.8 1.7 1 1 0 1 1 1 0 DASH complex subunit Spc34 RNAse_A_bac PF18431.1 EGB03004.1 - 0.58 11.1 4.9 0.45 11.5 2.5 2.0 1 1 1 2 2 2 0 Bacterial CdiA-CT RNAse A domain DUF4778 PF16008.5 EGB03004.1 - 1.6 8.8 10.2 1.7 8.7 9.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4778) Sel1 PF08238.12 EGB03005.1 - 5.1e-24 84.2 7.7 1.2e-08 35.4 0.2 4.4 4 1 0 4 4 4 4 Sel1 repeat TPR_12 PF13424.6 EGB03005.1 - 0.0016 18.7 6.6 0.37 11.1 3.3 3.9 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB03005.1 - 0.016 15.0 0.5 0.016 15.0 0.5 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB03005.1 - 0.022 14.6 1.4 0.022 14.6 1.4 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB03005.1 - 0.031 14.4 6.8 1.4 9.2 1.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB03005.1 - 0.035 14.3 4.5 0.15 12.3 0.6 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB03005.1 - 0.095 12.8 3.2 13 6.1 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB03005.1 - 0.3 11.8 10.1 1.3 9.8 2.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TxDE PF18711.1 EGB03006.1 - 0.12 12.5 0.1 8 6.7 0.0 3.0 4 0 0 4 4 4 0 Toxoflavin-degrading enzyme APH PF01636.23 EGB03006.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.11 EGB03006.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Las1 PF04031.13 EGB03007.1 - 5.5e-31 107.8 0.6 3.1e-30 105.3 0.6 2.1 1 1 0 1 1 1 1 Las1-like Methyltransf_31 PF13847.6 EGB03008.1 - 1.8e-06 27.8 0.0 4.1e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03008.1 - 0.0003 21.5 0.0 0.0017 19.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03008.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGB03008.1 - 0.019 15.0 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGB03008.1 - 0.067 12.7 0.0 0.41 10.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 EGB03008.1 - 0.1 13.3 0.0 0.53 11.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Sod_Ni PF09055.11 EGB03009.1 - 1.3e-19 71.0 0.0 1.7e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase MobC PF05713.11 EGB03009.1 - 0.017 15.6 0.6 0.048 14.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) Lig_chan PF00060.26 EGB03010.1 - 1.4e-08 34.7 0.6 2.9e-08 33.7 0.5 1.4 1 1 0 1 1 1 1 Ligand-gated ion channel DUF5493 PF17597.2 EGB03010.1 - 0.82 10.0 4.4 0.2 11.9 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5493) Chloroa_b-bind PF00504.21 EGB03011.1 - 1.7e-27 96.9 0.4 2.2e-27 96.6 0.4 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Aldo_ket_red PF00248.21 EGB03012.1 - 1.2e-62 211.7 0.0 1.7e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_18 PF00704.28 EGB03013.1 - 7.7e-17 62.0 0.0 1.1e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SnoaL PF07366.12 EGB03013.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase TRM PF02005.16 EGB03014.1 - 5.5e-92 308.9 0.0 6.5e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EGB03014.1 - 8.1e-05 22.5 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EGB03014.1 - 0.0042 17.8 0.3 0.014 16.1 0.3 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB03014.1 - 0.013 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FKBP_C PF00254.28 EGB03015.1 - 8.5e-29 99.7 0.0 1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Kinesin PF00225.23 EGB03017.1 - 6.7e-15 54.8 0.1 6.8e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB03017.1 - 1e-09 38.5 0.0 1.3e-09 38.1 0.0 1.3 1 1 0 1 1 1 1 Microtubule binding RNA_pol_Rpc34 PF05158.12 EGB03019.1 - 4.2e-61 207.2 3.4 5.7e-53 180.5 1.9 2.3 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit DUF2603 PF10788.9 EGB03019.1 - 0.0008 19.5 1.2 0.0052 16.8 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2603) RPA_C PF08784.11 EGB03019.1 - 0.0014 19.2 0.7 0.026 15.2 0.2 2.7 3 0 0 3 3 3 1 Replication protein A C terminal B-block_TFIIIC PF04182.12 EGB03019.1 - 0.0018 18.4 0.4 0.0036 17.4 0.4 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 EGB03019.1 - 0.009 15.9 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 MarR family Lipoxygenase PF00305.19 EGB03019.1 - 0.0093 14.4 0.1 0.011 14.2 0.1 1.1 1 0 0 1 1 1 1 Lipoxygenase Rio2_N PF09202.11 EGB03019.1 - 0.016 15.4 0.3 0.034 14.4 0.3 1.6 1 0 0 1 1 1 0 Rio2, N-terminal Sigma54_activ_2 PF14532.6 EGB03019.1 - 0.017 15.2 2.4 0.033 14.3 0.9 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF5101 PF17031.5 EGB03019.1 - 0.02 15.0 0.3 0.32 11.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) HTH_20 PF12840.7 EGB03019.1 - 0.031 14.3 0.1 0.081 13.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 EGB03019.1 - 0.054 14.0 1.8 0.092 13.3 0.4 2.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain TrmB PF01978.19 EGB03019.1 - 0.084 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 EGB03019.1 - 0.086 12.8 0.5 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family GlnD_UR_UTase PF08335.11 EGB03019.1 - 0.12 12.5 1.8 0.2 11.7 1.8 1.4 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase MarR PF01047.22 EGB03019.1 - 0.15 12.0 0.4 0.3 11.0 0.4 1.5 1 0 0 1 1 1 0 MarR family TFIIE_alpha PF02002.17 EGB03019.1 - 0.15 11.9 3.5 0.095 12.6 1.1 1.9 2 1 0 2 2 2 0 TFIIE alpha subunit Ets PF00178.22 EGB03019.1 - 0.25 11.8 1.0 0.58 10.7 1.0 1.6 1 0 0 1 1 1 0 Ets-domain TPR_2 PF07719.17 EGB03020.1 - 2.3e-08 33.5 8.7 0.00016 21.5 1.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB03020.1 - 2.5e-05 23.9 5.8 7.9e-05 22.3 1.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB03020.1 - 0.0002 21.3 2.4 0.015 15.4 0.5 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGB03020.1 - 0.00046 20.3 1.2 0.0022 18.1 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB03020.1 - 0.00048 20.7 8.6 0.0036 17.9 3.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB03020.1 - 0.0013 18.9 0.7 0.011 16.1 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB03020.1 - 0.0015 18.2 4.6 0.26 11.0 0.3 3.2 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 EGB03020.1 - 0.016 16.0 6.3 1.9 9.5 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB03020.1 - 0.018 15.1 0.6 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB03020.1 - 0.021 15.1 4.6 0.13 12.5 0.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB03020.1 - 0.035 14.6 3.8 0.66 10.5 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 EGB03020.1 - 0.048 14.1 3.4 4 7.9 0.2 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 EGB03020.1 - 0.058 13.6 0.2 0.15 12.3 0.1 1.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGB03020.1 - 1.2 10.0 4.1 50 4.8 0.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGB03020.1 - 2.6 8.9 11.3 13 6.7 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Tom5 PF10642.9 EGB03021.1 - 0.092 12.8 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase cobW PF02492.19 EGB03023.1 - 3.7e-27 95.1 0.0 4.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGB03023.1 - 0.0016 18.6 0.1 0.003 17.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB03023.1 - 0.0037 17.5 0.0 0.0057 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGB03023.1 - 0.018 14.9 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase MobB PF03205.14 EGB03023.1 - 0.027 14.4 0.1 0.19 11.6 0.1 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 EGB03023.1 - 0.046 13.8 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EGB03023.1 - 0.085 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TsaE PF02367.17 EGB03023.1 - 0.14 12.2 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EGB03023.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EGB03023.1 - 0.19 10.7 0.2 0.29 10.1 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGB03023.1 - 0.22 12.1 0.1 0.4 11.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGB03023.1 - 0.23 11.2 0.0 0.28 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AfaD PF05775.12 EGB03024.1 - 0.027 14.9 0.0 0.099 13.1 0.0 1.9 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein DUF5585 PF17823.1 EGB03024.1 - 0.15 11.0 1.4 0.25 10.3 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) O-FucT PF10250.9 EGB03026.1 - 1.6e-07 31.3 0.2 1.9e-07 31.1 0.2 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase XG_FTase PF03254.13 EGB03026.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase WD40 PF00400.32 EGB03027.1 - 5.7e-08 33.3 0.2 1.1e-05 26.1 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGB03027.1 - 0.018 14.0 0.0 0.022 13.8 0.0 1.3 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HTH_Tnp_1 PF01527.20 EGB03027.1 - 0.095 13.0 0.3 0.16 12.3 0.1 1.7 1 1 0 1 1 1 0 Transposase Sugar_tr PF00083.24 EGB03028.1 - 1.2e-11 44.1 2.4 1.4e-11 44.0 2.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB03028.1 - 1.8e-08 33.7 6.6 2.1e-08 33.5 6.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 EGB03028.1 - 0.0072 15.4 1.5 0.0078 15.3 1.5 1.1 1 0 0 1 1 1 1 PUCC protein MFS_1 PF07690.16 EGB03029.1 - 4.1e-05 22.7 2.0 0.00041 19.4 0.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB03029.1 - 0.0002 20.4 1.4 0.00021 20.3 1.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 EGB03029.1 - 0.032 12.8 0.1 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF4094 PF13334.6 EGB03029.1 - 0.098 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) LRR_6 PF13516.6 EGB03030.1 - 3.8e-39 129.4 34.6 1.1e-05 25.0 0.2 16.2 17 0 0 17 17 17 9 Leucine Rich repeat LRR_4 PF12799.7 EGB03030.1 - 9.2e-07 29.1 1.9 0.75 10.3 0.0 6.5 5 1 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB03030.1 - 0.0003 20.9 0.0 15 6.7 0.0 6.3 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 EGB03030.1 - 0.04 13.7 11.2 0.13 12.0 0.1 6.5 8 2 1 9 9 9 0 Leucine rich repeat His_Phos_2 PF00328.22 EGB03031.1 - 4.5e-05 23.0 0.0 0.00018 21.0 0.0 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) LapA_dom PF06305.11 EGB03031.1 - 0.14 12.0 0.3 0.32 10.9 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Mpv17_PMP22 PF04117.12 EGB03032.1 - 1.9e-07 31.2 1.1 3.6e-07 30.3 1.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family LCIB_C_CA PF18599.1 EGB03032.1 - 0.14 11.4 0.3 3.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Cytochrom_B562 PF07361.11 EGB03032.1 - 0.44 11.2 1.8 0.91 10.2 1.3 1.7 2 0 0 2 2 2 0 Cytochrome b562 Pro_isomerase PF00160.21 EGB03033.1 - 5.3e-41 140.5 0.0 6.4e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lipase_GDSL_2 PF13472.6 EGB03034.1 - 2.3e-06 28.2 0.0 2.5e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sulfatase PF00884.23 EGB03035.1 - 7.1e-30 104.5 0.0 7.7e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB03035.1 - 0.16 11.5 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Rtt106 PF08512.12 EGB03036.1 - 1.4e-14 54.2 0.1 3.8e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SPT16 PF08644.11 EGB03036.1 - 2.8e-08 34.1 1.1 5.7e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Astro_capsid_p PF12226.8 EGB03036.1 - 3.6 6.6 29.2 7.2 5.7 29.2 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pkinase PF00069.25 EGB03037.1 - 2e-49 168.3 0.0 2.6e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03037.1 - 4.6e-38 131.0 0.0 7.2e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB03037.1 - 1.4e-05 24.1 0.0 2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB03037.1 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGB03037.1 - 0.0052 15.8 0.1 0.0097 14.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB03037.1 - 0.022 14.7 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family EMP70 PF02990.16 EGB03038.1 - 6.1e-198 658.7 6.0 8.7e-198 658.2 6.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 CopD PF05425.13 EGB03038.1 - 0.0089 16.4 4.8 0.0089 16.4 4.8 3.0 4 1 0 4 4 4 1 Copper resistance protein D Chloroa_b-bind PF00504.21 EGB03039.1 - 1.7e-30 106.7 0.3 2.1e-30 106.4 0.3 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Sulfotransfer_3 PF13469.6 EGB03040.1 - 1.4e-14 55.0 1.0 3.2e-12 47.3 0.2 2.5 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB03040.1 - 0.00019 21.0 0.0 0.0019 17.7 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain BTV_NS2 PF04514.12 EGB03041.1 - 0.41 9.4 3.0 0.49 9.2 3.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Kelch_3 PF13415.6 EGB03042.1 - 1.8e-09 37.7 2.2 0.071 13.4 0.3 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EGB03042.1 - 3.7e-06 26.9 1.2 2 8.5 0.2 3.9 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB03042.1 - 0.00028 20.8 2.4 0.055 13.5 0.1 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 EGB03042.1 - 0.0021 18.0 0.2 19 5.5 0.0 4.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 EGB03042.1 - 0.0071 16.6 0.0 9 6.8 0.0 4.3 3 1 0 3 3 3 1 Kelch motif zf-HC5HC2H PF13771.6 EGB03042.1 - 0.014 15.6 1.5 0.033 14.5 1.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 EGB03042.1 - 0.021 14.7 5.7 0.07 13.0 5.7 1.9 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EGB03042.1 - 0.48 10.3 4.7 1.2 9.1 4.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 EGB03042.1 - 4.3 7.5 6.4 15 5.7 6.4 1.9 1 1 0 1 1 1 0 PHD-finger DEAD PF00270.29 EGB03043.1 - 2.9e-16 59.7 0.0 4.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB03043.1 - 7.1e-08 32.6 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGB03043.1 - 3.4e-06 27.4 0.0 7.9e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGB03043.1 - 0.0026 17.5 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGB03043.1 - 0.0082 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 EGB03043.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein mRNA_cap_C PF03919.15 EGB03046.1 - 2e-16 60.6 0.5 4.1e-16 59.5 0.5 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain ketoacyl-synt PF00109.26 EGB03048.1 - 2.6e-25 89.5 4.5 3.6e-25 89.0 4.5 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03048.1 - 0.00032 20.7 0.1 0.0006 19.8 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain OmpA PF00691.20 EGB03049.1 - 1.1e-08 35.3 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 OmpA family Sel1 PF08238.12 EGB03050.1 - 1.3e-24 86.1 11.6 7.2e-10 39.2 0.8 4.2 4 0 0 4 4 4 3 Sel1 repeat TPR_10 PF13374.6 EGB03050.1 - 0.29 11.1 7.5 6.9 6.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB03050.1 - 0.32 11.5 1.6 9 6.9 0.0 3.3 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB03050.1 - 0.58 10.5 8.7 2.2 8.7 1.0 4.1 1 1 1 2 2 2 0 Tetratricopeptide repeat NSF PF02071.20 EGB03050.1 - 5.1 8.3 6.4 1e+02 4.4 0.0 4.1 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.28 EGB03050.1 - 7 6.7 15.9 17 5.5 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB03050.1 - 9 7.2 6.7 8.6 7.2 0.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat PHD PF00628.29 EGB03051.1 - 2.6e-06 27.2 6.5 4.3e-06 26.5 6.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-CSL PF05207.13 EGB03051.1 - 0.44 10.3 2.6 1.8 8.3 2.6 2.0 1 1 0 1 1 1 0 CSL zinc finger C1_1 PF00130.22 EGB03051.1 - 4.9 7.1 10.6 0.69 9.9 5.2 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sel1 PF08238.12 EGB03052.1 - 2.3e-21 75.8 12.8 6.6e-05 23.4 0.2 5.9 5 1 0 5 5 5 5 Sel1 repeat FA_desaturase PF00487.24 EGB03053.1 - 9.9e-33 114.0 22.2 1.3e-32 113.6 22.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGB03053.1 - 1.6e-07 31.3 0.0 4.8e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GHD PF17834.1 EGB03053.1 - 0.011 15.7 0.0 0.054 13.5 0.0 2.1 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase Spo7 PF03907.13 EGB03053.1 - 0.059 12.8 1.3 0.088 12.3 0.4 1.7 2 0 0 2 2 2 0 Spo7-like protein DUF737 PF05300.11 EGB03054.1 - 0.043 14.2 5.8 0.069 13.5 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Snapin_Pallidin PF14712.6 EGB03054.1 - 0.053 13.9 0.4 0.087 13.3 0.4 1.3 1 0 0 1 1 1 0 Snapin/Pallidin DUF983 PF06170.12 EGB03054.1 - 0.057 13.8 0.2 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Hamartin PF04388.12 EGB03054.1 - 1.2 7.7 6.1 1.5 7.4 6.1 1.1 1 0 0 1 1 1 0 Hamartin protein Aminotran_1_2 PF00155.21 EGB03055.1 - 5.4e-22 78.5 0.0 6.8e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGB03055.1 - 3.8e-11 42.4 0.0 5.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase TP_methylase PF00590.20 EGB03056.1 - 2.6e-41 141.9 0.6 4.7e-41 141.1 0.6 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2880 PF11082.8 EGB03056.1 - 1.5 9.2 5.5 0.57 10.5 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) Fer2 PF00111.27 EGB03057.1 - 1.1e-12 47.7 1.0 4.1e-12 45.9 1.0 1.9 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain KRTAP PF11759.8 EGB03059.1 - 0.00067 20.2 52.9 1.8e+04 -11.2 52.9 2.9 1 1 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 EGB03059.1 - 0.0042 17.2 48.9 1.8e+04 -9.2 48.9 3.0 1 1 0 1 1 1 0 Keratin type II head ASCH PF04266.14 EGB03060.1 - 0.0099 16.5 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 ASCH domain DUF5308 PF17233.2 EGB03060.1 - 0.074 13.3 6.7 0.084 13.1 1.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5308) ETRAMP PF09716.10 EGB03060.1 - 0.12 12.4 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Metallophos_3 PF14582.6 EGB03060.1 - 0.14 11.5 0.0 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily TIM PF00121.18 EGB03062.1 - 8.8e-78 261.0 0.6 2e-77 259.9 0.6 1.5 1 1 0 1 1 1 1 Triosephosphate isomerase CRM1_repeat_3 PF18787.1 EGB03063.1 - 3.9e-29 100.5 3.1 7e-29 99.7 1.1 2.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 VID27_N PF17748.1 EGB03063.1 - 0.18 11.7 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 VID27 N-terminal region TRAPP PF04051.16 EGB03064.1 - 1.2e-24 86.7 0.0 1.2e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component IncFII_repA PF02387.15 EGB03064.1 - 0.0077 15.5 0.0 0.0088 15.3 0.0 1.1 1 0 0 1 1 1 1 IncFII RepA protein family ABC_tran PF00005.27 EGB03065.1 - 1.1e-17 64.8 0.0 1.6e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB03065.1 - 0.0054 16.6 0.0 0.014 15.2 0.0 1.6 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RRM_1 PF00076.22 EGB03066.1 - 2.2e-16 59.5 0.0 2.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB03066.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Sel1 PF08238.12 EGB03067.1 - 1.9e-45 152.3 33.9 8.8e-10 38.9 0.2 8.5 8 1 0 8 8 8 8 Sel1 repeat AAA_lid_10 PF17872.1 EGB03067.1 - 0.0014 18.7 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA lid domain DUF977 PF06163.11 EGB03067.1 - 0.01 15.8 0.9 0.17 11.8 0.0 2.6 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF977) DUF4715 PF15835.5 EGB03067.1 - 0.023 14.8 0.3 0.072 13.2 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4715) YicC_N PF03755.13 EGB03067.1 - 0.089 13.2 0.1 6.7 7.1 0.0 2.2 2 0 0 2 2 2 0 YicC-like family, N-terminal region B12-binding_2 PF02607.17 EGB03067.1 - 0.25 11.8 1.8 34 5.0 0.1 3.3 3 1 0 3 3 3 0 B12 binding domain TPR_3 PF07720.12 EGB03067.1 - 1.6 8.8 4.5 0.37 10.8 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RHH_1 PF01402.21 EGB03067.1 - 2.1 8.4 4.7 38 4.4 0.1 3.6 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family FYVE PF01363.21 EGB03068.1 - 0.0006 19.9 7.7 0.001 19.1 7.8 1.4 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGB03068.1 - 0.57 10.4 3.6 0.66 10.2 3.2 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 EGB03068.1 - 0.98 9.5 12.2 0.35 10.9 0.5 2.7 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.21 EGB03068.1 - 2.2 8.6 8.4 0.24 11.6 3.5 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 EGB03068.1 - 2.3 8.2 8.7 0.13 12.2 2.1 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS91 PF14319.6 EGB03068.1 - 3.3 7.8 9.1 0.2 11.7 2.2 2.2 1 1 2 3 3 3 0 Transposase zinc-binding domain Ribosomal_S17_N PF16205.5 EGB03069.1 - 1.4e-32 111.9 0.3 2.5e-32 111.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGB03069.1 - 2.8e-25 88.2 1.2 8.2e-25 86.7 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 SNO PF01174.19 EGB03070.1 - 1e-40 139.6 0.0 2e-39 135.4 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGB03070.1 - 1.2e-05 25.0 0.4 2.1e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EGB03070.1 - 0.0028 17.3 0.3 0.005 16.5 0.3 1.4 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EGB03070.1 - 0.0086 15.9 0.3 0.043 13.6 0.1 1.9 2 0 0 2 2 2 1 DJ-1/PfpI family GATase PF00117.28 EGB03070.1 - 0.025 14.3 0.3 0.13 12.0 0.3 1.9 1 1 0 1 1 1 0 Glutamine amidotransferase class-I DUF1611_N PF17396.2 EGB03070.1 - 0.18 12.1 0.9 3.1 8.1 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain HMG_CoA_synt_N PF01154.17 EGB03075.1 - 6.9e-22 78.1 0.1 7.5e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 EGB03076.1 - 1.4e-15 57.5 0.7 1.6e-15 57.3 0.7 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain RRM_1 PF00076.22 EGB03077.1 - 6.9e-16 57.8 0.0 8e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 EGB03077.1 - 0.003 17.2 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Sporulation protein family 7 RRM_5 PF13893.6 EGB03077.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGB03077.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EGB03077.1 - 0.23 11.7 0.0 1.1 9.5 0.0 1.8 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Aa_trans PF01490.18 EGB03078.1 - 1.3e-09 37.2 0.5 1.7e-09 36.9 0.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGB03078.1 - 0.024 13.7 0.5 0.033 13.2 0.5 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Sulfatase PF00884.23 EGB03080.1 - 6.3e-12 45.5 0.0 6.6e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB03080.1 - 0.024 14.3 0.0 0.025 14.2 0.0 1.0 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Methyltransf_23 PF13489.6 EGB03081.1 - 4e-13 49.5 0.0 5.8e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB03081.1 - 3.1e-08 34.1 0.1 1e-07 32.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03081.1 - 1.2e-07 32.4 0.0 7.6e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03081.1 - 1.1e-06 29.2 0.0 6.1e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB03081.1 - 0.00015 21.6 0.0 0.0065 16.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_14 PF08484.11 EGB03081.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Ubie_methyltran PF01209.18 EGB03081.1 - 0.098 12.0 0.0 1.5 8.1 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGB03082.1 - 1.7e-07 31.8 0.4 5.1e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03082.1 - 1.9e-07 31.1 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB03082.1 - 3.1e-06 27.7 0.1 9.9e-06 26.1 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03082.1 - 8.2e-05 23.3 0.0 0.00019 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB03082.1 - 0.054 13.3 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EGB03082.1 - 0.27 10.6 0.0 0.99 8.8 0.0 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB DUF543 PF04418.12 EGB03085.1 - 0.2 11.7 3.8 0.57 10.2 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Band_7 PF01145.25 EGB03086.1 - 5.3e-09 36.3 0.2 8.2e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGB03086.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family TBPIP_N PF15517.6 EGB03086.1 - 0.086 12.9 0.7 0.26 11.3 0.7 1.7 1 1 0 1 1 1 0 TBP-interacting protein N-terminus GidB PF02527.15 EGB03087.1 - 1e-22 80.4 0.0 1.1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 EGB03087.1 - 0.0058 16.2 0.0 0.0066 16.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain DUF563 PF04577.14 EGB03088.1 - 4.2e-14 53.2 0.0 6.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Big_5 PF13205.6 EGB03088.1 - 0.28 11.9 4.9 15 6.3 0.0 5.0 6 1 0 6 6 6 0 Bacterial Ig-like domain Pho88 PF10032.9 EGB03089.1 - 1.5e-22 79.7 0.0 2.1e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) RNA_pol_3_Rpc31 PF11705.8 EGB03089.1 - 0.00023 21.5 9.5 0.00028 21.2 9.5 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 EGB03089.1 - 0.011 15.8 6.6 0.0099 15.9 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cytomega_UL84 PF06284.11 EGB03089.1 - 0.036 12.5 2.0 0.038 12.5 2.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PGA2 PF07543.12 EGB03089.1 - 0.081 12.9 9.1 0.14 12.1 9.1 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 SDA1 PF05285.12 EGB03089.1 - 0.17 11.3 11.7 0.21 11.0 11.7 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGB03089.1 - 4.1 6.7 14.7 4.7 6.4 14.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGB03089.1 - 6.7 4.8 18.1 7.8 4.6 18.1 1.0 1 0 0 1 1 1 0 Nop14-like family Helicase_C PF00271.31 EGB03094.1 - 7.7e-15 55.2 0.0 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGB03094.1 - 0.00011 21.5 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase EII-Sor PF03609.14 EGB03094.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 PTS system sorbose-specific iic component LRR_8 PF13855.6 EGB03095.1 - 5.3e-28 96.6 0.3 1.4e-07 31.2 0.0 4.7 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EGB03095.1 - 5.2e-19 68.0 5.9 0.0029 18.0 0.0 5.4 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB03095.1 - 3.8e-13 48.0 4.8 6.3 7.8 0.0 9.2 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 EGB03095.1 - 0.0012 18.8 31.7 9.6 6.5 0.1 9.2 10 0 0 10 10 10 5 Leucine Rich repeat Chaperone_III PF07824.12 EGB03095.1 - 0.4 10.9 8.4 12 6.2 0.1 4.6 2 2 4 6 6 6 0 Type III secretion chaperone domain DBC1 PF14443.6 EGB03095.1 - 6.2 6.8 4.8 3.9e+02 1.0 0.1 4.6 4 2 2 6 6 6 0 DBC1 Ephrin_rec_like PF07699.13 EGB03096.1 - 1.9e-12 46.8 41.0 2.9e-07 30.1 4.2 3.6 1 1 2 3 3 3 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB03096.1 - 0.028 14.8 3.7 0.028 14.8 3.7 5.2 1 1 5 6 6 6 0 TNFR/NGFR cysteine-rich region VSP PF03302.13 EGB03096.1 - 1.5 7.6 32.7 2.1 7.1 2.4 2.0 1 1 1 2 2 2 0 Giardia variant-specific surface protein DUF2318 PF10080.9 EGB03096.1 - 7.8 6.7 19.8 3.2 7.9 9.0 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) ubiquitin PF00240.23 EGB03097.1 - 1.7e-32 111.0 0.0 2.9e-24 84.6 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EGB03097.1 - 5.6e-12 45.3 0.0 1.8e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB03097.1 - 2e-08 34.6 0.3 7.6e-07 29.5 0.0 2.9 2 1 0 2 2 2 1 Ubiquitin-like domain YukD PF08817.10 EGB03097.1 - 0.0082 16.8 0.0 0.82 10.4 0.0 2.3 2 1 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD FERM_f0 PF16511.5 EGB03097.1 - 0.015 15.6 0.1 0.35 11.2 0.1 2.7 2 1 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM TBK1_ULD PF18396.1 EGB03097.1 - 0.017 15.0 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGB03097.1 - 0.069 13.2 0.1 12 6.0 0.0 2.8 2 1 1 3 3 3 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB03097.1 - 0.1 12.7 0.0 0.44 10.7 0.0 2.0 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like UCH PF00443.29 EGB03098.1 - 9e-41 140.1 0.0 1.1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB03098.1 - 2.3e-14 53.7 0.0 1.9e-11 44.2 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Beta-lactamase PF00144.24 EGB03099.1 - 2.4e-24 86.2 7.7 1.1e-23 84.0 7.7 1.8 1 1 0 1 1 1 1 Beta-lactamase DUF4097 PF13349.6 EGB03100.1 - 8.3e-05 22.1 0.1 0.00011 21.7 0.1 1.2 1 0 0 1 1 1 1 Putative adhesin DUF2807 PF10988.8 EGB03100.1 - 4.6 7.0 15.7 0.11 12.3 5.8 2.6 1 1 2 3 3 3 0 Putative auto-transporter adhesin, head GIN domain Glu_cyclase_2 PF05096.12 EGB03101.1 - 8.5e-58 195.7 0.0 9.6e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase Aminotran_1_2 PF00155.21 EGB03102.1 - 1.2e-10 41.1 0.0 1.5e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ECH_1 PF00378.20 EGB03102.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Methyltransf_25 PF13649.6 EGB03104.1 - 0.041 14.6 0.1 0.12 13.1 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03104.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PIH1 PF08190.12 EGB03105.1 - 4.2e-26 91.4 0.3 1.1e-25 90.0 0.3 1.6 1 1 0 1 1 1 1 PIH1 N-terminal domain GHL15 PF14885.6 EGB03107.1 - 7e-10 39.3 2.7 0.00017 21.6 0.1 2.3 2 0 0 2 2 2 2 Hypothetical glycosyl hydrolase family 15 IBR PF01485.21 EGB03108.1 - 4.7e-10 39.5 16.9 0.00049 20.3 1.2 4.3 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 EGB03108.1 - 6.7e-05 22.8 1.8 6.7e-05 22.8 1.8 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGB03108.1 - 0.00095 19.5 2.5 0.00095 19.5 2.5 3.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 EGB03108.1 - 0.001 18.8 2.1 0.001 18.8 2.1 3.5 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGB03108.1 - 0.0015 18.3 0.5 0.0015 18.3 0.5 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB03108.1 - 0.0098 15.7 0.8 0.0098 15.7 0.8 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB03108.1 - 0.024 14.7 0.4 0.024 14.7 0.4 3.2 3 0 0 3 3 3 0 RING-type zinc-finger C1_4 PF07975.12 EGB03108.1 - 3.1 8.1 11.1 6 7.2 1.4 3.0 2 0 0 2 2 2 0 TFIIH C1-like domain ABC1 PF03109.16 EGB03109.1 - 8.8e-14 51.7 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 ABC1 family NAD_binding_8 PF13450.6 EGB03111.1 - 0.12 12.6 0.1 0.93 9.8 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ketoacyl-synt PF00109.26 EGB03112.1 - 1.7e-20 73.7 2.2 2.4e-20 73.2 2.2 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03112.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EGB03112.1 - 0.095 12.6 0.5 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-PARP PF00645.18 EGB03113.1 - 1.1e-10 42.2 1.8 2.6e-10 41.0 1.8 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RimK PF08443.11 EGB03113.1 - 0.00059 19.5 0.0 0.0027 17.3 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 EGB03113.1 - 0.055 12.9 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.22 EGB03113.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Acyl_transf_1 PF00698.21 EGB03115.1 - 0.0089 15.6 0.0 0.73 9.3 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain SAT PF16073.5 EGB03115.1 - 0.087 12.5 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF2674 PF10879.8 EGB03119.1 - 0.21 11.1 0.0 5.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) DUF4429 PF14472.6 EGB03120.1 - 0.032 14.8 0.0 0.04 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4429) EF-hand_6 PF13405.6 EGB03122.1 - 2.4e-07 30.1 1.0 0.0025 17.6 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB03122.1 - 1.7e-06 27.2 0.5 0.0034 16.8 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB03122.1 - 7.6e-06 26.3 0.5 1.1e-05 25.8 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB03122.1 - 9.2e-05 21.8 2.0 0.12 11.9 0.1 2.4 2 0 0 2 2 2 2 EF hand Autophagy_act_C PF03987.15 EGB03124.1 - 0.077 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain AFT PF08731.11 EGB03124.1 - 0.12 12.8 0.3 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Transcription factor AFT ketoacyl-synt PF00109.26 EGB03125.1 - 2.1e-33 116.0 8.0 2.7e-33 115.6 8.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SNF2_N PF00176.23 EGB03126.1 - 1.2e-11 44.0 0.0 1.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain STELLO PF03385.17 EGB03127.1 - 2.3e-16 59.6 0.0 2.6e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 STELLO glycosyltransferases STELLO PF03385.17 EGB03128.1 - 1.9e-15 56.6 0.0 2.5e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases ketoacyl-synt PF00109.26 EGB03130.1 - 1.1e-11 44.8 3.6 1.2e-11 44.7 3.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain CD20 PF04103.15 EGB03130.1 - 0.035 14.2 4.5 0.039 14.1 4.5 1.0 1 0 0 1 1 1 0 CD20-like family DUF5455 PF17537.2 EGB03130.1 - 0.036 14.5 1.0 0.04 14.3 1.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5455) SLATT_6 PF18169.1 EGB03130.1 - 0.057 13.0 1.2 0.061 12.9 1.2 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 SLATT_5 PF18160.1 EGB03130.1 - 1.2 8.5 3.9 1.3 8.3 3.9 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 cNMP_binding PF00027.29 EGB03131.1 - 9.7e-15 54.4 0.1 1.1e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RGS PF00615.19 EGB03131.1 - 6.8e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain EF-hand_7 PF13499.6 EGB03137.1 - 5.6e-19 68.4 1.1 5e-05 23.7 0.6 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGB03137.1 - 6.7e-15 53.5 10.5 0.00057 19.2 0.2 5.7 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 EGB03137.1 - 2.2e-13 49.0 2.6 0.014 15.3 0.0 5.6 5 1 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EGB03137.1 - 1.8e-10 40.5 3.0 0.0031 17.3 0.1 4.7 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB03137.1 - 4.2e-10 38.7 6.3 0.34 10.5 0.1 5.5 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 EGB03137.1 - 0.016 15.5 0.0 0.069 13.5 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain SUB1_ProdP9 PF18213.1 EGB03137.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Pkinase PF00069.25 EGB03138.1 - 1e-30 107.0 0.0 1.1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03138.1 - 2.4e-13 50.0 0.0 2.7e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB03138.1 - 0.039 13.3 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB03138.1 - 0.17 11.7 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CBAH PF02275.18 EGB03139.1 - 8.8e-20 71.6 0.0 1.3e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Kelch_6 PF13964.6 EGB03139.1 - 7.2e-17 61.0 6.4 0.00054 20.2 0.1 9.3 8 2 1 9 9 8 2 Kelch motif Kelch_1 PF01344.25 EGB03139.1 - 3.6e-16 58.5 8.4 2.1e-05 24.0 0.0 8.3 8 2 0 8 8 8 3 Kelch motif Kelch_5 PF13854.6 EGB03139.1 - 6.1e-14 51.6 1.0 0.075 13.0 0.0 8.2 8 0 0 8 8 8 2 Kelch motif Kelch_4 PF13418.6 EGB03139.1 - 4.5e-12 45.8 1.2 0.16 12.0 0.0 8.0 7 1 1 8 8 8 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGB03139.1 - 2.3e-09 36.8 7.0 0.58 10.2 0.0 8.3 9 1 0 9 9 9 3 Kelch motif Kelch_3 PF13415.6 EGB03139.1 - 9.5e-09 35.3 16.2 0.0014 18.9 0.1 9.1 10 1 0 10 10 9 2 Galactose oxidase, central domain Methyltransf_22 PF13383.6 EGB03139.1 - 0.00011 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain F-box-like PF12937.7 EGB03139.1 - 0.00014 21.7 0.1 0.00043 20.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like Methyltransf_21 PF05050.12 EGB03139.1 - 0.0048 16.9 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain F-box PF00646.33 EGB03139.1 - 0.018 14.9 0.2 0.034 14.0 0.2 1.4 1 0 0 1 1 1 0 F-box domain Ribosomal_S9 PF00380.19 EGB03140.1 - 6.1e-49 165.6 0.2 7.1e-49 165.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Peptidase_M48 PF01435.18 EGB03141.1 - 4.5e-44 150.6 0.0 6e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 EGB03141.1 - 8.9e-07 29.0 1.3 8.9e-07 29.0 1.3 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M56 PF05569.11 EGB03141.1 - 0.0075 15.5 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 EGB03141.1 - 0.008 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_A24 PF01478.18 EGB03141.1 - 0.039 14.4 1.4 0.17 12.3 1.4 1.9 1 1 0 1 1 1 0 Type IV leader peptidase family DUF2268 PF10026.9 EGB03141.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF4538 PF15061.6 EGB03141.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF2201_N PF13203.6 EGB03141.1 - 0.18 11.4 0.3 0.26 10.8 0.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Ribosomal_L29 PF00831.23 EGB03142.1 - 1.5e-07 31.3 1.3 1.5e-07 31.3 1.3 2.5 1 1 1 2 2 2 1 Ribosomal L29 protein DNA_pack_N PF02500.15 EGB03142.1 - 0.093 12.5 0.5 0.13 12.0 0.3 1.2 1 1 0 1 1 1 0 Probable DNA packing protein, N-terminus Aminotran_1_2 PF00155.21 EGB03143.1 - 4.6e-41 141.2 0.0 5e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGB03143.1 - 7.5e-06 24.7 0.0 1.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGB03143.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Mito_carr PF00153.27 EGB03144.1 - 2.2e-37 126.8 0.1 4.2e-13 49.0 0.1 3.0 1 1 2 3 3 3 3 Mitochondrial carrier protein B9-C2 PF07162.11 EGB03145.1 - 1.2e-43 149.2 0.1 1.3e-43 149.1 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF2733 PF10813.8 EGB03145.1 - 2.4 8.0 4.4 1.4 8.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) DEAD PF00270.29 EGB03146.1 - 3.7e-40 137.6 0.0 5.1e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB03146.1 - 7e-29 100.4 0.7 2.3e-28 98.8 0.5 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB03146.1 - 0.00012 22.1 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGB03146.1 - 0.0018 17.5 0.1 0.0026 17.0 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EGB03146.1 - 0.022 14.1 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DS PF01916.17 EGB03146.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase ER_lumen_recept PF00810.18 EGB03147.1 - 2.9e-49 167.7 10.1 5e-49 166.9 10.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGB03147.1 - 0.0037 17.0 6.2 0.38 10.6 0.3 3.8 3 1 1 4 4 4 2 PQ loop repeat AAA_6 PF12774.7 EGB03148.1 - 3.3e-111 371.4 0.0 1.5e-110 369.2 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB03148.1 - 4.7e-61 207.1 0.0 1.2e-60 205.7 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGB03148.1 - 5.8e-61 205.4 0.0 1.3e-60 204.3 0.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGB03148.1 - 3.6e-30 104.8 0.0 5.6e-24 84.6 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_5 PF07728.14 EGB03148.1 - 1.6e-28 99.4 0.0 2.4e-19 69.7 0.0 4.9 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_8 PF12780.7 EGB03148.1 - 2e-28 99.4 0.0 2.8e-27 95.7 0.0 2.9 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 EGB03148.1 - 1.1e-24 87.2 3.0 1.9e-24 86.4 3.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGB03148.1 - 8e-15 55.0 0.0 2.3e-13 50.3 0.0 3.2 3 1 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 EGB03148.1 - 9.2e-12 45.7 9.0 0.0061 17.0 0.0 7.0 7 0 0 7 7 5 3 AAA ATPase domain AAA_22 PF13401.6 EGB03148.1 - 1.3e-08 35.2 0.0 0.36 11.1 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 EGB03148.1 - 8.2e-08 32.7 0.5 0.19 12.2 0.0 4.8 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_lid_11 PF18198.1 EGB03148.1 - 2.3e-07 30.8 0.0 4.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain RsgA_GTPase PF03193.16 EGB03148.1 - 0.00013 21.9 0.1 0.023 14.6 0.0 3.7 4 0 0 4 4 4 1 RsgA GTPase Rad17 PF03215.15 EGB03148.1 - 0.00016 21.6 0.0 0.12 12.3 0.1 3.8 4 0 0 4 4 4 1 Rad17 P-loop domain AAA_24 PF13479.6 EGB03148.1 - 0.00023 20.9 0.1 0.04 13.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EGB03148.1 - 0.0015 18.2 0.1 0.21 11.4 0.0 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EGB03148.1 - 0.0026 18.0 0.0 0.94 9.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGB03148.1 - 0.0031 17.9 0.0 4.2 7.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 EGB03148.1 - 0.0045 16.7 5.2 5.1 6.8 0.1 4.3 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 EGB03148.1 - 0.0051 17.0 0.1 0.17 12.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 EGB03148.1 - 0.0051 16.8 0.0 4 7.3 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 EGB03148.1 - 0.0089 15.7 0.2 11 5.7 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGB03148.1 - 0.015 15.1 1.7 0.21 11.3 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein T2SSE PF00437.20 EGB03148.1 - 0.018 14.1 0.0 0.076 12.1 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 EGB03148.1 - 0.027 15.0 0.0 6.3 7.4 0.0 3.3 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 EGB03148.1 - 0.13 12.8 6.3 0.34 11.4 0.0 4.2 6 0 0 6 6 4 0 ABC transporter PP_M1 PF03012.14 EGB03148.1 - 0.23 11.0 0.6 0.41 10.1 0.6 1.3 1 0 0 1 1 1 0 Phosphoprotein AAA_13 PF13166.6 EGB03148.1 - 0.37 9.4 3.3 0.25 10.0 0.3 1.8 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 EGB03148.1 - 0.55 9.1 12.6 1.7 7.4 4.2 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_19 PF13245.6 EGB03148.1 - 0.65 10.3 4.4 30 4.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain TMF_TATA_bd PF12325.8 EGB03148.1 - 1.3 9.3 9.5 2.4 8.4 1.2 3.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CREPT PF16566.5 EGB03148.1 - 4.5 7.4 8.5 0.5 10.5 0.1 2.8 3 0 0 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour Tropomyosin_1 PF12718.7 EGB03148.1 - 8.6 6.5 10.1 0.14 12.3 2.1 2.1 2 0 0 2 2 1 0 Tropomyosin like adh_short PF00106.25 EGB03149.1 - 5.8e-18 65.0 0.3 3.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGB03149.1 - 2.1e-13 50.4 4.6 2e-07 30.8 1.2 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB03149.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 KR domain Pkinase PF00069.25 EGB03151.1 - 1.7e-38 132.5 0.0 1.9e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03151.1 - 2e-21 76.4 0.0 2.3e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB03151.1 - 0.0021 17.1 0.1 0.0024 16.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB03151.1 - 0.0023 17.9 0.2 0.027 14.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB03151.1 - 0.013 14.9 0.2 0.02 14.3 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB03151.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Mre11_DNA_bind PF04152.14 EGB03152.1 - 1.1e-32 113.7 0.0 1.7e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGB03152.1 - 3.7e-11 43.9 0.1 5.6e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB03152.1 - 5.8e-07 29.8 0.0 4.1e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BUD22 PF09073.10 EGB03152.1 - 0.00034 20.1 13.2 0.00039 19.9 12.1 1.5 2 0 0 2 2 2 1 BUD22 Nop53 PF07767.11 EGB03152.1 - 0.1 12.0 7.4 0.15 11.4 7.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 EGB03152.1 - 0.25 9.5 8.0 0.35 9.0 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGB03152.1 - 0.64 9.4 10.1 1 8.7 10.1 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 EGB03152.1 - 1.7 7.2 23.6 2.4 6.7 23.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Prothymosin PF03247.14 EGB03152.1 - 2.3 8.7 20.9 2.3 8.7 6.5 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family DHHA1 PF02272.19 EGB03152.1 - 5.7 7.4 8.7 1.3 9.4 0.8 2.5 2 0 0 2 2 2 0 DHHA1 domain Ion_trans PF00520.31 EGB03153.1 - 0.0014 17.9 0.6 0.0017 17.6 0.6 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGB03153.1 - 0.38 9.4 2.5 0.5 9.0 2.5 1.2 1 0 0 1 1 1 0 Polycystin cation channel Pro_isomerase PF00160.21 EGB03154.1 - 1.3e-26 93.8 0.0 1.6e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PsbP PF01789.16 EGB03155.1 - 0.0042 17.2 0.1 0.012 15.8 0.1 1.8 1 1 0 1 1 1 1 PsbP ROK PF00480.20 EGB03156.1 - 1.6e-08 34.4 1.3 0.0061 16.1 0.0 2.9 1 1 2 3 3 3 2 ROK family FGGY_N PF00370.21 EGB03156.1 - 0.0067 16.0 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Pkinase PF00069.25 EGB03157.1 - 7.8e-60 202.5 0.0 8.8e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03157.1 - 1.6e-37 129.2 0.0 2.1e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB03157.1 - 0.0014 17.5 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGB03157.1 - 0.0042 16.1 0.1 0.0053 15.7 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB03157.1 - 0.0054 16.1 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGB03157.1 - 0.057 12.5 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGB03157.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 EGB03158.1 - 1.8e-61 204.1 4.9 2.1e-21 75.7 0.0 4.5 3 1 1 4 4 4 4 Mitochondrial carrier protein Sde2_N_Ubi PF13019.6 EGB03159.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain MFS_1 PF07690.16 EGB03160.1 - 2.5e-10 39.8 28.9 4e-06 26.0 8.8 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2070 PF09843.9 EGB03160.1 - 4.8 5.4 6.9 1.4 7.2 4.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) PHTB1_C PF14728.6 EGB03161.1 - 1.1e-77 261.7 0.1 6.1e-77 259.2 0.1 1.8 1 1 0 1 1 1 1 PTHB1 C-terminus MFS_1_like PF12832.7 EGB03163.1 - 1.4e-19 70.2 8.6 1.4e-18 66.9 3.0 2.2 1 1 0 2 2 2 2 MFS_1 like family Cullin PF00888.22 EGB03164.1 - 2.6e-109 366.6 7.0 7.5e-109 365.1 6.9 1.6 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGB03164.1 - 4.9e-16 58.5 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain S-AdoMet_synt_C PF02773.16 EGB03165.1 - 5.7e-63 211.0 0.2 1e-61 207.0 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGB03165.1 - 1.8e-43 147.6 0.0 4e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGB03165.1 - 1.7e-41 140.9 0.5 4.1e-41 139.7 0.5 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EGB03165.1 - 0.035 12.9 0.9 0.25 10.1 0.2 2.3 3 0 0 3 3 3 0 S-adenosylmethionine synthetase (AdoMet synthetase) ADH_zinc_N PF00107.26 EGB03165.1 - 0.096 12.7 0.1 0.82 9.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Kinesin PF00225.23 EGB03166.1 - 1.1e-99 333.5 0.2 1.3e-99 333.3 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB03166.1 - 6.8e-27 94.2 0.1 1.2e-26 93.5 0.1 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_30 PF13604.6 EGB03166.1 - 0.064 13.0 0.2 0.61 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain PIF1 PF05970.14 EGB03166.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase WD40 PF00400.32 EGB03167.1 - 2.9e-33 113.3 18.2 3.2e-07 30.9 0.4 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB03167.1 - 3.4e-07 30.5 0.2 1.8 8.9 0.2 4.9 1 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB03167.1 - 8.4e-05 21.4 3.8 0.23 10.1 0.0 4.5 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGB03167.1 - 0.0013 17.8 1.5 3.3 6.6 0.0 4.1 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 EGB03167.1 - 0.0032 17.9 0.2 1 9.9 0.0 3.7 4 1 0 4 4 4 1 PQQ-like domain PALB2_WD40 PF16756.5 EGB03167.1 - 0.077 11.9 1.6 0.1 11.5 0.0 2.0 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain APS_kinase PF01583.20 EGB03168.1 - 8.6e-58 194.7 0.0 1.3e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EGB03168.1 - 3.7e-28 98.2 0.0 1.5e-26 93.0 0.0 2.4 2 0 0 2 2 2 1 PUA-like domain ATP-sulfurylase PF01747.17 EGB03168.1 - 4.8e-18 65.4 0.0 7.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase AAA_33 PF13671.6 EGB03168.1 - 1.8e-05 24.9 0.0 3.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB03168.1 - 0.0021 18.6 0.0 0.0062 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGB03168.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 EGB03168.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EGB03168.1 - 0.076 12.8 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 EGB03168.1 - 0.094 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 EGB03168.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB03168.1 - 0.17 12.4 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter HA2 PF04408.23 EGB03170.1 - 6.5e-20 71.4 0.0 2.2e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGB03170.1 - 4.4e-13 49.4 0.0 7.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGB03170.1 - 9.5e-11 42.0 0.0 2.3e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB03170.1 - 7.1e-05 22.6 0.4 0.00027 20.7 0.4 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGB03170.1 - 0.00025 20.8 0.1 0.00058 19.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB03170.1 - 0.00025 21.3 0.3 0.00093 19.5 0.3 1.9 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGB03170.1 - 0.0041 16.2 0.0 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 EGB03170.1 - 0.013 15.7 1.8 0.12 12.6 0.1 3.1 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGB03170.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGB03170.1 - 0.022 15.1 0.2 0.054 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Flavi_DEAD PF07652.14 EGB03170.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 EGB03170.1 - 0.046 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB03170.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EGB03170.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB03170.1 - 0.082 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EGB03170.1 - 0.091 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EGB03170.1 - 0.19 11.7 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CN_hydrolase PF00795.22 EGB03172.1 - 5.6e-48 163.6 0.0 6.8e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pro_Al_protease PF02983.14 EGB03172.1 - 0.32 11.1 5.1 0.15 12.2 0.5 2.8 3 0 0 3 3 3 0 Alpha-lytic protease prodomain Peptidase_M22 PF00814.25 EGB03173.1 - 2.8e-70 237.1 0.0 3.6e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EGB03173.1 - 0.015 14.9 0.0 0.87 9.2 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus Kinesin PF00225.23 EGB03174.1 - 8.1e-21 74.3 0.0 2.5e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGB03174.1 - 2.3e-09 37.4 0.0 3.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding HECT PF00632.25 EGB03175.1 - 5e-06 26.2 0.0 5.4e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PP-binding PF00550.25 EGB03176.1 - 3.2e-08 33.8 0.0 3.2e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGB03176.1 - 0.0026 17.9 0.1 0.0029 17.8 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier Pyr_redox_3 PF13738.6 EGB03177.1 - 2.6e-67 227.2 0.0 3.2e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB03177.1 - 1.8e-08 34.0 3.9 0.038 13.2 0.0 3.5 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB03177.1 - 9.5e-07 28.7 4.5 0.00025 20.7 0.3 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EGB03177.1 - 6.1e-06 25.6 0.1 0.00019 20.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGB03177.1 - 1.3e-05 25.6 1.5 0.99 10.0 1.2 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB03177.1 - 0.0016 17.8 3.3 4 6.6 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain Etmic-2 PF06670.11 EGB03177.1 - 0.0023 17.0 0.5 0.004 16.2 0.1 1.6 2 0 0 2 2 2 1 Microneme protein Etmic-2 Thi4 PF01946.17 EGB03177.1 - 0.02 14.2 0.8 1.1 8.5 0.3 2.2 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 EGB03177.1 - 0.1 11.6 0.4 0.21 10.6 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGB03177.1 - 0.11 11.6 12.6 1.4 7.9 0.0 3.1 2 1 1 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.6 EGB03177.1 - 0.33 10.9 2.8 2 8.4 2.8 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EGB03177.1 - 0.57 9.5 2.7 2.2 7.5 0.9 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGB03177.1 - 0.63 8.7 7.1 3.5 6.2 5.4 2.6 2 1 1 3 3 3 0 HI0933-like protein LRR_9 PF14580.6 EGB03179.1 - 1.4e-10 41.0 0.0 3.9e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGB03179.1 - 1.5e-06 28.5 0.4 0.087 13.3 0.1 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB03179.1 - 4.5e-06 26.3 0.1 5.4e-05 22.9 0.0 2.5 3 0 0 3 3 3 1 Leucine rich repeat HpaB_N PF11794.8 EGB03180.1 - 1.3e-90 303.7 0.0 1.8e-90 303.3 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 EGB03180.1 - 1.1e-69 233.6 0.1 1.6e-69 233.1 0.1 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Myb_DNA-binding PF00249.31 EGB03181.1 - 5.9e-19 68.0 0.6 6.3e-19 67.9 0.6 1.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB03181.1 - 4.8e-13 49.2 0.2 5.2e-13 49.0 0.2 1.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyco_transf_8 PF01501.20 EGB03182.1 - 2.9e-25 89.3 0.0 3.5e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 EGB03182.1 - 0.0005 19.6 0.0 0.0007 19.1 0.0 1.1 1 0 0 1 1 1 1 Glucosyltransferase 24 GatB_N PF02934.15 EGB03184.1 - 8.5e-87 291.0 0.0 9.9e-87 290.8 0.0 1.0 1 0 0 1 1 1 1 GatB/GatE catalytic domain DUF2218 PF09981.9 EGB03184.1 - 0.045 14.1 0.1 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) SAM_1 PF00536.30 EGB03185.1 - 0.094 13.2 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AA_kinase PF00696.28 EGB03186.1 - 3.3e-44 151.3 4.7 4e-44 151.0 4.7 1.1 1 0 0 1 1 1 1 Amino acid kinase family Lin0512_fam PF09585.10 EGB03186.1 - 0.013 15.6 0.7 0.03 14.3 0.7 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) TTL PF03133.15 EGB03187.1 - 9.7e-86 287.5 0.0 1.2e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB03187.1 - 2.4e-08 33.5 0.0 0.0045 16.3 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGB03187.1 - 0.00019 20.8 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Ribosomal_L12 PF00542.19 EGB03188.1 - 1.2e-28 99.3 9.4 1.3e-27 96.0 6.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGB03188.1 - 1.2e-17 63.3 5.8 1.2e-17 63.3 5.8 2.8 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DAHP_snth_FXD PF18152.1 EGB03188.1 - 0.13 12.2 1.8 0.26 11.1 0.2 2.3 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain FAM221 PF14753.6 EGB03189.1 - 4.9e-14 52.4 3.4 2.6e-13 50.0 3.4 1.8 1 1 0 1 1 1 1 Protein FAM221A/B DUF2072 PF09845.9 EGB03189.1 - 0.73 10.1 3.3 1.7 8.9 3.3 1.6 1 1 0 1 1 1 0 Zn-ribbon containing protein Acetyltransf_1 PF00583.25 EGB03190.1 - 1.1e-15 57.9 0.1 1.5e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGB03190.1 - 3e-11 43.6 0.1 4.1e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGB03190.1 - 3.2e-11 43.3 0.0 4.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGB03190.1 - 8.4e-08 32.5 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB03190.1 - 9e-06 25.6 0.1 1.6e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGB03190.1 - 6.8e-05 23.0 0.0 9.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGB03190.1 - 0.00042 20.0 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGB03190.1 - 0.0015 18.0 0.0 0.0021 17.6 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGB03190.1 - 0.0049 17.0 0.0 0.0088 16.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EGB03190.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 EGB03190.1 - 0.015 15.4 0.1 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGB03190.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 EGB03190.1 - 0.07 13.8 0.0 0.086 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 EGB03190.1 - 0.07 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldedh PF00171.22 EGB03191.1 - 8.4e-139 463.0 0.5 1.4e-88 297.4 3.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family TetR_C_6 PF13977.6 EGB03191.1 - 8.1 6.7 18.2 6.4 7.0 4.4 4.2 3 1 1 4 4 4 0 BetI-type transcriptional repressor, C-terminal Radical_SAM PF04055.21 EGB03192.1 - 8.6e-15 55.5 0.1 1.2e-14 55.0 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily DUF2378 PF09536.10 EGB03192.1 - 0.044 13.6 0.1 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) Peptidase_M24 PF00557.24 EGB03192.1 - 0.091 12.4 0.2 0.44 10.2 0.1 2.0 1 1 1 2 2 2 0 Metallopeptidase family M24 Methyltransf_11 PF08241.12 EGB03193.1 - 4.4e-24 85.0 0.0 6.6e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03193.1 - 1e-20 74.2 0.0 1.7e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03193.1 - 3.9e-20 72.3 0.0 5.6e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03193.1 - 2e-16 60.5 0.0 3.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB03193.1 - 1.7e-13 50.6 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB03193.1 - 6.9e-11 41.9 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EGB03193.1 - 8.7e-07 28.7 0.0 3.3e-06 26.9 0.0 1.8 2 1 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 EGB03193.1 - 0.00034 20.2 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EGB03193.1 - 0.00034 20.0 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 EGB03193.1 - 0.00043 20.6 0.0 0.00075 19.8 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_24 PF13578.6 EGB03193.1 - 0.0022 19.0 0.1 0.0064 17.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 EGB03193.1 - 0.0079 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 EGB03193.1 - 0.057 13.3 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase TPMT PF05724.11 EGB03193.1 - 0.064 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EGB03193.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGB03193.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGB03193.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ephrin_rec_like PF07699.13 EGB03194.1 - 2.3e-12 46.5 502.3 0.00071 19.3 8.1 48.3 30 16 13 47 47 47 31 Putative ephrin-receptor like Invasin_D3 PF09134.10 EGB03194.1 - 1.1 9.6 7.1 0.38 11.1 1.3 3.1 2 1 0 2 2 2 0 Invasin, domain 3 Big_2 PF02368.18 EGB03194.1 - 4.1 7.4 7.3 8.3 6.4 7.3 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Aminotran_5 PF00266.19 EGB03195.1 - 3.5e-34 118.4 0.0 5.1e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGB03195.1 - 8.6e-05 21.9 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Sigma70_ner PF04546.13 EGB03196.1 - 0.0085 16.0 3.1 0.0085 16.0 3.1 2.4 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF4972 PF16342.5 EGB03196.1 - 0.039 13.7 0.1 0.2 11.4 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) DnaB_bind PF10410.9 EGB03196.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.2 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase PPP4R2 PF09184.11 EGB03196.1 - 4.5 6.8 7.2 1.8 8.1 4.7 1.6 2 0 0 2 2 2 0 PPP4R2 Sugar_tr PF00083.24 EGB03197.1 - 2.1e-57 195.0 5.3 2e-55 188.5 5.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB03197.1 - 1.5e-21 76.7 29.7 2.3e-18 66.3 29.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily SET PF00856.28 EGB03197.1 - 0.00032 21.1 0.0 0.00057 20.3 0.0 1.4 1 0 0 1 1 1 1 SET domain MFS_Mycoplasma PF07672.13 EGB03197.1 - 0.0072 15.6 0.2 0.16 11.2 0.5 2.2 2 0 0 2 2 2 1 Mycoplasma MFS transporter Ribosomal_L12 PF00542.19 EGB03198.1 - 3e-13 49.9 0.1 3.6e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain HTH_22 PF13309.6 EGB03198.1 - 0.038 14.1 0.4 0.64 10.1 0.2 2.1 1 1 1 2 2 2 0 HTH domain LEDGF PF11467.8 EGB03198.1 - 0.071 12.7 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) EF-hand_1 PF00036.32 EGB03199.1 - 5.2e-12 44.4 1.0 3.8e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB03199.1 - 8e-09 34.6 5.1 2.2e-05 23.8 0.1 2.7 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB03199.1 - 2.2e-08 33.4 2.4 0.00038 20.1 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGB03199.1 - 5.3e-08 33.2 0.2 6.5e-08 32.9 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB03199.1 - 3.7e-07 29.9 2.0 0.02 14.8 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB03199.1 - 0.00036 20.8 0.0 0.00041 20.6 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain Rdx PF10262.9 EGB03200.1 - 3.4e-11 43.2 0.1 3.9e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Rdx family adh_short PF00106.25 EGB03201.1 - 2.8e-26 92.2 2.3 4.1e-26 91.7 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB03201.1 - 4.2e-17 62.5 1.2 5.9e-17 62.0 1.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB03201.1 - 0.00037 20.5 1.7 0.00085 19.3 1.7 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGB03201.1 - 0.0057 16.6 2.8 0.014 15.3 2.8 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sulfatase PF00884.23 EGB03202.1 - 1.8e-24 86.7 0.0 1.9e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB03202.1 - 0.00045 19.9 0.0 0.00058 19.6 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGB03202.1 - 0.023 13.3 0.0 0.028 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Na_Ca_ex PF01699.24 EGB03203.1 - 5.5e-17 62.1 9.8 6.5e-17 61.9 9.8 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein AAA_32 PF13654.6 EGB03203.1 - 0.08 11.7 0.0 0.098 11.4 0.0 1.0 1 0 0 1 1 1 0 AAA domain Na_Ca_ex PF01699.24 EGB03204.1 - 1.5e-21 77.0 13.3 1.7e-21 76.8 13.3 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein HA PF03457.14 EGB03205.1 - 6.2e-29 100.1 0.0 1.6e-09 38.0 0.0 6.0 6 0 0 6 6 6 4 Helicase associated domain SAP PF02037.27 EGB03205.1 - 6.3e-06 25.8 0.0 1.8e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 SAP domain NOA36 PF06524.12 EGB03205.1 - 0.0043 16.4 13.1 0.0043 16.4 13.1 1.5 2 0 0 2 2 2 1 NOA36 protein Cwf_Cwc_15 PF04889.12 EGB03205.1 - 0.021 14.5 12.8 0.04 13.7 12.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 EGB03205.1 - 0.53 10.5 15.7 1.2 9.3 15.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 EGB03205.1 - 3.8 6.6 26.1 7.2 5.6 26.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 EGB03205.1 - 4.2 7.2 11.1 6.8 6.6 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 EGB03206.1 - 2.4e-34 118.5 0.3 3e-34 118.2 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB03206.1 - 5.2e-24 85.1 3.1 6.4e-24 84.8 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB03206.1 - 4.3e-05 23.5 2.2 6.6e-05 22.9 2.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB03206.1 - 0.049 13.1 0.9 0.078 12.4 0.9 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NYN PF01936.18 EGB03207.1 - 1.2e-07 32.3 0.0 1.8e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 NYN domain 2OG-FeII_Oxy PF03171.20 EGB03209.1 - 4.3e-07 30.4 0.0 8.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NIF PF03031.18 EGB03209.1 - 5e-05 23.1 0.0 9.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sulfotransfer_4 PF17784.1 EGB03210.1 - 0.0085 15.9 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain COesterase PF00135.28 EGB03211.1 - 8.9e-40 137.0 0.9 9.5e-40 136.9 0.9 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGB03211.1 - 8.9e-14 51.9 3.8 1.6e-13 51.0 3.8 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 EGB03211.1 - 0.0033 17.0 2.2 0.0055 16.2 2.2 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EGB03211.1 - 0.0042 17.7 8.1 0.0052 17.4 8.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGB03211.1 - 0.019 14.5 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EGB03211.1 - 0.073 11.9 0.1 2.1 7.1 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EGB03211.1 - 0.62 9.3 3.5 4.8 6.4 3.3 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB03212.1 - 8.2e-07 28.9 0.2 1.3e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB03212.1 - 2.4e-06 28.3 10.8 3e-06 28.0 10.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 EGB03212.1 - 0.26 10.2 0.0 0.33 9.8 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) WD40 PF00400.32 EGB03213.1 - 0.015 16.2 10.5 0.45 11.5 0.8 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Taxilin PF09728.9 EGB03213.1 - 0.21 10.7 2.1 0.34 10.0 2.1 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein APG17 PF04108.12 EGB03213.1 - 0.33 10.0 2.9 26 3.8 0.2 3.2 3 0 0 3 3 3 0 Autophagy protein Apg17 XG_FTase PF03254.13 EGB03214.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase NUDIX PF00293.28 EGB03216.1 - 8e-10 38.9 0.3 8.4e-09 35.6 0.0 2.7 4 0 0 4 4 4 1 NUDIX domain DUF3246 PF11596.8 EGB03216.1 - 0.0022 17.4 1.1 0.0036 16.8 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Glycos_transf_2 PF00535.26 EGB03216.1 - 0.11 12.3 0.1 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 PBP1_TM PF14812.6 EGB03216.1 - 0.15 12.5 8.3 0.31 11.4 8.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Retinal PF15449.6 EGB03216.1 - 0.18 9.6 2.8 0.25 9.1 2.8 1.1 1 0 0 1 1 1 0 Retinal protein NOA36 PF06524.12 EGB03216.1 - 0.44 9.8 8.2 0.68 9.2 8.2 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EGB03216.1 - 0.51 10.0 1.3 0.83 9.3 1.3 1.2 1 0 0 1 1 1 0 FAM176 family Trypan_PARP PF05887.11 EGB03216.1 - 0.55 10.2 14.3 1.6 8.7 14.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cwf_Cwc_15 PF04889.12 EGB03216.1 - 0.58 9.8 11.2 1 9.0 11.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 EGB03216.1 - 1.3 9.3 6.0 2.7 8.3 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 EGB03216.1 - 1.6 9.1 13.6 3.4 8.1 13.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EGB03216.1 - 1.8 8.6 4.4 3 7.9 4.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 EGB03216.1 - 8.6 5.4 14.2 16 4.5 14.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) adh_short PF00106.25 EGB03217.1 - 3.8e-15 55.9 0.9 2.2e-11 43.6 0.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGB03217.1 - 6.4e-06 25.9 0.1 0.0026 17.3 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB03217.1 - 6.1e-05 23.0 0.2 0.00011 22.2 0.2 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EGB03217.1 - 0.011 14.8 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 EGB03217.1 - 0.038 13.4 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family His_Phos_1 PF00300.22 EGB03219.1 - 2.7e-33 115.3 0.1 9.2e-26 90.7 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 EGB03220.1 - 2.9e-19 69.5 0.0 1.6e-11 44.3 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) RINGv PF12906.7 EGB03221.1 - 7.1e-11 42.1 2.7 1.3e-10 41.2 2.7 1.5 1 0 0 1 1 1 1 RING-variant domain ABC1 PF03109.16 EGB03222.1 - 8.8e-14 51.7 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 ABC1 family ABC1 PF03109.16 EGB03225.1 - 7.8e-25 87.4 0.0 4.6e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EGB03225.1 - 0.0021 18.0 8.5 0.0046 16.9 0.1 3.8 3 1 1 4 4 4 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB03225.1 - 0.0058 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EGB03225.1 - 0.053 12.9 0.0 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain WaaY PF06176.11 EGB03225.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Sulfatase PF00884.23 EGB03226.1 - 2.4e-16 60.0 0.0 2.9e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB03226.1 - 7.6e-06 25.7 0.0 8.5e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Histone PF00125.24 EGB03227.1 - 5.3e-19 68.9 0.4 6.3e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB03227.1 - 1.9e-05 24.8 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB03227.1 - 0.0038 17.7 0.0 0.0059 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB03227.1 - 0.053 13.6 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein CENP-T_C PF15511.6 EGB03228.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB03228.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB03228.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB03228.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB03228.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB03228.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB03228.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGB03228.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) DUF1624 PF07786.12 EGB03229.1 - 6e-10 39.1 2.5 7.6e-10 38.7 0.6 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 EGB03229.1 - 0.0081 15.7 3.3 0.53 9.7 3.3 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5009) Acyl_transf_3 PF01757.22 EGB03229.1 - 0.21 10.6 13.1 0.018 14.1 2.4 2.7 1 1 0 2 2 2 0 Acyltransferase family ABC_tran PF00005.27 EGB03230.1 - 6.8e-25 88.2 0.0 8.8e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB03230.1 - 1.9e-05 24.7 0.4 5.5e-05 23.1 0.3 1.8 2 1 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EGB03230.1 - 0.00013 21.5 0.2 0.094 12.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB03230.1 - 0.00089 19.0 0.7 0.019 14.7 0.2 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGB03230.1 - 0.0011 19.4 0.1 0.0086 16.5 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGB03230.1 - 0.0014 18.5 0.3 0.87 9.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGB03230.1 - 0.0015 18.1 1.4 0.099 12.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGB03230.1 - 0.0033 17.1 0.3 0.0083 15.9 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB03230.1 - 0.0046 17.0 0.3 0.0088 16.1 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 EGB03230.1 - 0.014 15.8 0.3 1.6 9.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGB03230.1 - 0.014 15.6 0.2 0.03 14.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EGB03230.1 - 0.015 14.9 0.4 0.028 14.0 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGB03230.1 - 0.022 15.2 0.1 6.5 7.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGB03230.1 - 0.024 15.1 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EGB03230.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 EGB03230.1 - 0.043 13.7 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 EGB03230.1 - 0.094 12.0 0.0 0.23 10.7 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.9 EGB03230.1 - 0.097 11.4 0.2 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NACHT PF05729.12 EGB03230.1 - 0.11 12.4 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 EGB03230.1 - 0.12 12.6 0.1 0.34 11.1 0.3 1.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGB03230.1 - 0.13 12.3 0.3 0.2 11.7 0.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain MukB PF04310.12 EGB03230.1 - 0.16 11.8 0.2 0.27 11.0 0.2 1.3 1 0 0 1 1 1 0 MukB N-terminal ATPase_2 PF01637.18 EGB03230.1 - 0.23 11.3 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Methyltransf_23 PF13489.6 EGB03232.1 - 2.1e-07 30.9 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03232.1 - 2.1e-07 31.5 0.4 5.9e-07 30.1 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB03232.1 - 2.6e-06 28.0 0.1 8e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03232.1 - 9.5e-05 23.1 0.0 0.00021 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB03232.1 - 0.057 13.2 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EGB03232.1 - 0.24 10.8 0.0 0.72 9.2 0.0 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB LRR_8 PF13855.6 EGB03234.1 - 2.4e-09 36.8 0.2 1.2e-08 34.6 0.0 2.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EGB03234.1 - 1.6e-07 31.6 0.5 0.0026 18.1 0.0 3.2 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB03234.1 - 0.00095 19.0 0.0 1.4 9.2 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 EGB03234.1 - 0.021 15.3 0.3 11 7.1 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Phage_integrase PF00589.22 EGB03236.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_integrase PF00589.22 EGB03238.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family UDPGT PF00201.18 EGB03239.1 - 0.00085 18.2 0.0 0.0016 17.3 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase RD3 PF14473.6 EGB03241.1 - 0.033 14.0 0.2 0.077 12.8 0.2 1.5 1 0 0 1 1 1 0 RD3 protein Nucleotid_trans PF03407.16 EGB03243.1 - 0.0085 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 EGB03243.1 - 0.021 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Apt1 PF10351.9 EGB03243.1 - 0.089 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ank_2 PF12796.7 EGB03247.1 - 5.6e-14 52.5 0.0 4.4e-06 27.2 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB03247.1 - 6e-11 42.6 0.0 0.0043 17.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB03247.1 - 1.1e-10 40.8 0.3 0.85 10.4 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EGB03247.1 - 0.0001 22.5 4.0 1.2 9.5 0.0 4.6 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB03247.1 - 0.001 19.4 3.3 43 4.8 0.0 6.0 6 0 0 6 6 6 0 Ankyrin repeat SIR2 PF02146.17 EGB03247.1 - 0.0039 17.1 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DprA_WH PF17782.1 EGB03247.1 - 0.12 12.5 4.8 7.8 6.7 1.2 3.4 3 0 0 3 3 3 0 DprA winged helix domain HTH_Tnp_Tc3_2 PF01498.18 EGB03248.1 - 0.00058 20.1 0.1 0.0015 18.8 0.1 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 EGB03248.1 - 0.061 14.0 1.5 0.086 13.5 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Sporozoite_P67 PF05642.11 EGB03249.1 - 2.9 5.9 3.9 3.8 5.5 3.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DZR PF12773.7 EGB03250.1 - 0.009 16.0 1.2 0.014 15.4 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon RskA PF10099.9 EGB03250.1 - 0.033 14.5 5.2 0.033 14.5 5.2 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Nudix_N_2 PF14803.6 EGB03250.1 - 0.3 11.0 2.4 3.5 7.6 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal FXMRP1_C_core PF12235.8 EGB03250.1 - 0.58 10.8 6.0 0.059 14.0 1.9 1.4 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal TMF_DNA_bd PF12329.8 EGB03252.1 - 0.062 13.3 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 EGB03252.1 - 0.18 11.6 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 STELLO PF03385.17 EGB03253.1 - 2.6e-15 56.2 0.0 3.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases STELLO PF03385.17 EGB03254.1 - 3.3e-15 55.8 0.0 4.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases ARL2_Bind_BART PF11527.8 EGB03257.1 - 2e-15 56.9 0.0 3.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART WW PF00397.26 EGB03257.1 - 2e-07 30.9 0.3 4.9e-07 29.7 0.3 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 EGB03258.1 - 1.5e-10 41.0 0.1 5.4e-10 39.1 0.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain CPDase PF07823.11 EGB03258.1 - 0.038 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Formyl_trans_N PF00551.19 EGB03259.1 - 7.5e-36 123.5 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Mrr_cat PF04471.12 EGB03259.1 - 0.094 12.7 0.0 0.48 10.4 0.0 2.0 1 1 1 2 2 2 0 Restriction endonuclease Form_Nir_trans PF01226.17 EGB03260.1 - 7.1e-47 159.7 15.0 9.5e-47 159.3 15.0 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Cyanate_lyase PF02560.14 EGB03261.1 - 2e-28 98.1 0.1 2.7e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Vps62 PF06101.11 EGB03261.1 - 0.0063 14.9 0.0 0.0081 14.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 MFS_5 PF05631.14 EGB03261.1 - 0.05 12.5 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM HTH_31 PF13560.6 EGB03261.1 - 0.055 13.8 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PDZ_2 PF13180.6 EGB03263.1 - 0.00041 20.6 0.1 0.00078 19.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EGB03263.1 - 0.00072 19.4 1.6 0.0026 17.6 1.6 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGB03263.1 - 0.0058 16.9 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain RMMBL PF07521.12 EGB03263.1 - 0.11 12.5 0.0 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain GluR_Homer-bdg PF10606.9 EGB03263.1 - 0.35 11.1 3.0 8.2 6.7 0.1 2.7 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor DHFR_1 PF00186.19 EGB03265.1 - 3.9e-25 88.4 0.0 4.8e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Aldedh PF00171.22 EGB03266.1 - 2.8e-13 49.2 4.3 1.1e-12 47.3 0.9 2.8 3 0 0 3 3 3 1 Aldehyde dehydrogenase family GSHPx PF00255.19 EGB03267.1 - 1.2e-33 114.9 0.1 9.7e-32 108.8 0.1 2.1 1 1 0 1 1 1 1 Glutathione peroxidase Rdx PF10262.9 EGB03268.1 - 6.6e-29 99.9 0.0 9.1e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family Phlebovirus_G2 PF07245.11 EGB03269.1 - 0.034 12.7 0.0 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Med26 PF08711.11 EGB03270.1 - 2.8e-13 49.7 0.0 7e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Radial_spoke PF04712.12 EGB03271.1 - 5.9e-12 45.3 0.0 6.6e-05 22.1 0.0 2.3 2 1 0 2 2 2 2 Radial spokehead-like protein AAA_34 PF13872.6 EGB03272.1 - 5e-122 406.5 0.0 6.1e-122 406.2 0.0 1.1 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ResIII PF04851.15 EGB03272.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C_4 PF13871.6 EGB03273.1 - 8.2e-83 278.2 0.0 1.2e-82 277.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue NMT_C PF02799.15 EGB03274.1 - 2.4e-73 246.1 0.0 3.2e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EGB03274.1 - 3e-70 235.2 0.0 1.9e-69 232.6 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 EGB03274.1 - 0.016 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EGB03274.1 - 0.016 15.3 0.0 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Beach PF02138.18 EGB03275.1 - 1.5e-99 332.8 0.0 1.8e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGB03275.1 - 2.1e-06 27.7 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Dynein_light PF01221.18 EGB03276.1 - 4.2e-44 148.8 1.4 4.6e-44 148.6 1.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 EGB03276.1 - 0.064 12.7 0.0 0.073 12.5 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Ectatomin PF06457.11 EGB03276.1 - 0.18 11.8 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Ectatomin 2OG-FeII_Oxy_2 PF13532.6 EGB03277.1 - 4.7e-15 56.3 0.0 7.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB03277.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily GETHR PF05671.11 EGB03277.1 - 1.9 7.9 13.9 2.7e+03 -2.1 13.9 3.2 1 1 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) DUF4456 PF14644.6 EGB03278.1 - 2.1e-64 217.0 0.6 1.2e-63 214.6 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4456) DUF4455 PF14643.6 EGB03278.1 - 4.5e-64 216.8 23.4 5.2e-51 173.7 1.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4455) Sel1 PF08238.12 EGB03281.1 - 7.3e-22 77.3 12.6 3.3e-08 33.9 0.1 4.3 4 1 0 4 4 4 3 Sel1 repeat TPR_12 PF13424.6 EGB03281.1 - 0.00031 21.0 2.3 0.056 13.7 0.3 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EGB03281.1 - 0.0096 16.0 3.1 0.056 13.5 0.2 2.7 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EGB03281.1 - 0.014 15.5 12.7 0.53 10.5 0.6 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB03281.1 - 0.02 14.8 9.2 0.43 10.5 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB03281.1 - 0.11 13.0 1.7 1.7 9.2 0.0 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB03281.1 - 0.11 12.4 12.6 0.23 11.3 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB03281.1 - 0.42 10.9 4.9 14 6.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Chloroa_b-bind PF00504.21 EGB03282.1 - 9.9e-24 84.7 0.0 1.3e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein 2OG-FeII_Oxy_3 PF13640.6 EGB03283.1 - 5.6e-12 46.4 0.0 1.1e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Importin_rep_4 PF18808.1 EGB03283.1 - 3.4e-08 33.7 0.0 3.4e-08 33.7 0.0 3.1 4 0 0 4 4 4 1 Importin repeat AhpC-TSA PF00578.21 EGB03284.1 - 3.6e-21 75.3 0.0 4.8e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGB03284.1 - 4.1e-09 36.3 0.0 4.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGB03284.1 - 5.4e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 EGB03284.1 - 0.001 19.2 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ank_2 PF12796.7 EGB03285.1 - 1.6e-10 41.4 0.2 1.7e-10 41.3 0.2 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB03285.1 - 3.6e-08 33.0 0.1 0.004 17.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGB03285.1 - 3.1e-07 30.8 0.0 0.024 15.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB03285.1 - 6.3e-07 29.6 0.7 0.012 16.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB03285.1 - 1e-06 28.9 0.5 0.0013 19.0 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.25 EGB03286.1 - 2.7e-05 24.4 0.1 6.2e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PCB_OB PF17092.5 EGB03286.1 - 0.092 13.5 0.1 13 6.6 0.1 2.5 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain ArfGap PF01412.18 EGB03287.1 - 7.2e-14 51.9 0.0 7.3e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TPR_2 PF07719.17 EGB03289.1 - 1.4e-07 31.1 3.3 0.0014 18.6 0.4 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB03289.1 - 0.0001 21.9 0.2 0.038 13.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat CS PF04969.16 EGB03289.1 - 0.00036 21.5 0.0 0.00073 20.5 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_12 PF13424.6 EGB03289.1 - 0.0016 18.7 5.8 0.018 15.3 0.6 3.5 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB03289.1 - 0.0017 18.4 0.0 2.7 8.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB03289.1 - 0.017 15.9 0.8 0.017 15.9 0.8 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB03289.1 - 0.032 14.7 19.1 0.43 11.1 3.5 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat SPRY PF00622.28 EGB03289.1 - 0.043 13.9 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 SPRY domain EMP24_GP25L PF01105.24 EGB03290.1 - 1.7e-29 103.1 0.0 2e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IP_trans PF02121.18 EGB03290.1 - 0.048 13.2 0.2 0.11 12.0 0.1 1.6 1 1 1 2 2 2 0 Phosphatidylinositol transfer protein Aldedh PF00171.22 EGB03291.1 - 2.3e-75 253.9 0.0 2.6e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGB03291.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Epimerase PF01370.21 EGB03293.1 - 2.3e-20 73.1 0.0 3.3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB03293.1 - 1.6e-12 47.7 0.6 2.8e-12 46.9 0.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGB03293.1 - 2.2e-12 46.6 0.0 2.9e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGB03293.1 - 1.2e-11 44.3 0.0 2.4e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EGB03293.1 - 1.2e-07 31.5 0.0 5.5e-06 26.1 0.1 2.3 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EGB03293.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGB03293.1 - 0.014 14.5 0.1 0.04 13.0 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 EGB03294.1 - 4.9e-22 78.5 0.0 5.4e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03294.1 - 1.3e-11 44.3 0.0 1.4e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB03294.1 - 0.0095 15.9 2.9 0.47 10.3 0.4 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB03294.1 - 0.015 14.6 0.0 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pyr_redox_2 PF07992.14 EGB03295.1 - 4.2e-24 85.3 1.7 6.8e-24 84.6 1.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB03295.1 - 2.3e-05 24.8 0.4 0.00065 20.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB03295.1 - 0.0085 15.7 6.8 6 6.3 0.1 4.0 2 2 2 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGB03295.1 - 0.015 14.3 0.1 0.41 9.7 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein DUF4423 PF14394.6 EGB03295.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) NAD_binding_9 PF13454.6 EGB03295.1 - 0.019 15.0 0.5 35 4.4 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGB03295.1 - 0.035 14.3 0.6 0.66 10.2 0.0 2.7 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_S9 PF00326.21 EGB03295.1 - 0.22 11.0 0.7 0.63 9.5 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family GIDA PF01134.22 EGB03295.1 - 0.41 9.7 3.7 27 3.7 0.0 3.1 3 1 0 3 3 3 0 Glucose inhibited division protein A 2OG-FeII_Oxy_3 PF13640.6 EGB03296.1 - 1.9e-09 38.3 0.1 2.5e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB03296.1 - 0.061 13.8 0.0 0.081 13.4 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DXP_synthase_N PF13292.6 EGB03297.1 - 2.6e-103 345.0 0.0 4.8e-103 344.1 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 EGB03297.1 - 5.2e-38 130.5 0.0 9.9e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGB03297.1 - 6.2e-22 77.8 0.3 1.7e-21 76.4 0.1 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 EGB03297.1 - 1.2e-05 24.5 0.0 0.085 11.8 0.0 2.7 3 0 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 EGB03297.1 - 0.0015 17.6 0.1 0.0026 16.8 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Ribul_P_3_epim PF00834.19 EGB03298.1 - 5.1e-88 293.6 0.0 6e-88 293.4 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EGB03298.1 - 5.5e-06 26.3 0.0 0.00026 20.8 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EGB03298.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF4516 PF14990.6 EGB03298.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DUF1077 PF06417.12 EGB03299.1 - 2.5e-37 127.5 2.7 2.9e-37 127.3 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Ank_4 PF13637.6 EGB03300.1 - 4.6e-20 71.7 0.4 9.5e-11 42.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB03300.1 - 2.4e-17 62.7 7.4 1e-09 38.5 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB03300.1 - 9.8e-16 58.1 0.3 1.4e-15 57.7 0.3 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB03300.1 - 8.3e-11 41.1 1.8 0.0016 18.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EGB03300.1 - 1.9e-10 40.7 5.8 7e-05 23.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGB03301.1 - 1.2e-14 54.5 2.3 4.6e-09 36.6 0.3 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB03301.1 - 4e-12 46.1 3.3 3.1e-07 30.5 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB03301.1 - 3.4e-11 43.6 0.5 4.1e-11 43.3 0.5 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB03301.1 - 2.5e-08 33.5 0.4 0.00015 21.9 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EGB03301.1 - 1.9e-06 28.1 3.2 3.9e-05 23.9 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeat DnaJ PF00226.31 EGB03302.1 - 2.3e-20 72.5 0.2 2.7e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 DnaJ domain tRNA-synt_1b PF00579.25 EGB03304.1 - 9.5e-81 271.3 0.0 1.2e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NDUF_B6 PF09782.9 EGB03304.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Peptidase_M24 PF00557.24 EGB03305.1 - 1.8e-25 89.9 0.1 2.3e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 SHIPPO-rpt PF07004.12 EGB03306.1 - 3.8e-06 27.6 28.8 0.28 12.2 0.1 6.8 6 1 0 6 6 6 4 Sperm-tail PG-rich repeat EF-hand_1 PF00036.32 EGB03307.1 - 6.6e-23 78.5 14.4 1.8e-05 24.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB03307.1 - 7e-22 77.7 9.2 1.3e-10 41.6 1.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB03307.1 - 2.6e-19 67.4 10.4 9.1e-05 22.1 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB03307.1 - 3.1e-17 62.1 16.7 1e-07 31.7 1.0 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB03307.1 - 5.6e-14 50.9 14.2 0.0011 18.4 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGB03307.1 - 5.3e-05 23.5 1.7 0.022 15.1 0.1 2.8 1 1 2 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB03307.1 - 0.00042 20.6 0.8 0.37 11.1 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGB03307.1 - 0.002 18.1 7.7 0.13 12.2 0.5 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Clathrin_lg_ch PF01086.17 EGB03307.1 - 0.058 13.4 0.3 0.084 12.9 0.3 1.2 1 0 0 1 1 1 0 Clathrin light chain TPR_1 PF00515.28 EGB03308.1 - 3.3e-09 36.2 0.1 0.00031 20.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB03308.1 - 2.7e-08 33.3 2.5 0.0066 16.5 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB03308.1 - 3.7e-06 26.7 0.2 0.14 12.4 0.1 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat Methyltransf_28 PF02636.17 EGB03308.1 - 4.2e-05 23.3 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_12 PF13424.6 EGB03308.1 - 0.00034 20.8 1.6 0.0049 17.1 0.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB03308.1 - 0.007 16.9 1.0 9.4 7.1 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB03308.1 - 0.014 15.1 1.1 0.18 11.5 0.1 2.8 2 1 1 3 3 3 0 TPR repeat TPR_19 PF14559.6 EGB03308.1 - 0.077 13.5 0.0 0.39 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB03308.1 - 0.14 12.3 0.5 3.5 7.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FragX_IP PF05994.11 EGB03309.1 - 6.5e-142 474.4 1.2 7.2e-142 474.3 1.2 1.0 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family CNOT11 PF10155.9 EGB03310.1 - 8.2e-54 181.1 0.7 9.1e-54 180.9 0.7 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 CAF1C_H4-bd PF12265.8 EGB03311.1 - 2.3e-25 88.7 0.2 9e-25 86.7 0.1 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGB03311.1 - 3.2e-17 62.6 12.5 7.6e-05 23.4 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB03311.1 - 0.0024 18.1 1.5 0.051 13.9 0.1 2.6 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 EGB03311.1 - 0.026 14.6 0.0 0.53 10.4 0.0 2.5 1 1 1 2 2 2 0 Herpesvirus UL41A CD36 PF01130.21 EGB03312.1 - 2.2e-19 69.3 0.1 2.3e-16 59.4 0.0 2.4 2 1 0 2 2 2 2 CD36 family Sec7 PF01369.20 EGB03313.1 - 7.8e-55 185.4 0.0 3e-54 183.5 0.0 2.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EGB03313.1 - 2.2e-13 50.4 0.8 5.5e-13 49.1 0.8 1.7 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase PF00069.25 EGB03314.1 - 5.3e-53 180.1 0.0 5.9e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03314.1 - 1.1e-27 97.0 0.0 1.3e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB03314.1 - 0.018 14.4 0.1 0.063 12.6 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB03314.1 - 0.029 13.3 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGB03314.1 - 0.03 14.3 0.1 0.063 13.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family PseudoU_synth_2 PF00849.22 EGB03315.1 - 2.6e-08 34.1 0.0 7.2e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 RNA pseudouridylate synthase BET PF17035.5 EGB03317.1 - 2.7e-25 88.3 1.2 5.7e-25 87.3 1.2 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 EGB03317.1 - 2.8e-07 30.5 0.0 4.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF4349 PF14257.6 EGB03317.1 - 0.086 12.3 0.2 0.31 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Plasmid_RAQPRD PF09686.10 EGB03317.1 - 0.62 10.3 3.7 4.8 7.5 1.6 2.5 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) ATP_bind_3 PF01171.20 EGB03318.1 - 3.4e-23 82.3 0.1 5.1e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 PP-loop family Zip PF02535.22 EGB03318.1 - 0.094 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter C2 PF00168.30 EGB03319.1 - 0.00063 20.0 0.0 0.0036 17.6 0.0 2.1 2 0 0 2 2 2 1 C2 domain Pkinase PF00069.25 EGB03320.1 - 2.7e-19 69.6 0.1 3.3e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03320.1 - 6.9e-08 32.1 0.1 8.5e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Imm7 PF15585.6 EGB03320.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 Immunity protein 7 Arm PF00514.23 EGB03322.1 - 0.0024 17.9 6.6 3 8.0 0.0 4.3 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Mito_carr PF00153.27 EGB03323.1 - 5.4e-14 51.9 9.6 5.8e-06 26.1 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein Ribosomal_60s PF00428.19 EGB03323.1 - 4.7 7.9 10.1 7.5 7.2 10.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein PepSY_2 PF13670.6 EGB03323.1 - 6.3 6.9 7.7 11 6.1 7.7 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ank_2 PF12796.7 EGB03325.1 - 8.6e-22 77.5 0.1 1.9e-10 41.2 1.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB03325.1 - 6.2e-19 68.1 1.1 1.5e-05 25.4 0.2 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB03325.1 - 2.4e-16 59.5 1.2 0.00036 20.8 0.4 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB03325.1 - 6.2e-16 56.9 2.4 0.0004 20.6 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EGB03325.1 - 3.6e-12 46.1 7.4 0.00022 21.5 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat DSPc PF00782.20 EGB03325.1 - 1.1e-09 38.2 0.0 3e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain TUDOR_5 PF18359.1 EGB03326.1 - 0.12 12.1 1.7 0.2 11.4 0.6 2.0 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 ANAPC15 PF15243.6 EGB03327.1 - 0.14 12.5 0.1 0.32 11.4 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Cas_NE0113 PF09623.10 EGB03328.1 - 0.037 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Cpn60_TCP1 PF00118.24 EGB03329.1 - 2.5e-76 257.3 0.0 3.5e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_trans_1_2 PF13524.6 EGB03330.1 - 2.2e-06 28.0 0.1 5.3e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kelch_4 PF13418.6 EGB03331.1 - 3.4e-13 49.4 0.3 2.5e-07 30.6 0.1 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB03331.1 - 6.5e-10 38.8 0.1 1.9e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 EGB03331.1 - 1.1e-09 38.2 0.1 2.1e-07 31.0 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 EGB03331.1 - 3.5e-07 29.9 1.0 0.00013 21.8 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 EGB03331.1 - 3.9e-07 30.2 7.9 1.5e-05 25.1 0.1 3.6 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EGB03331.1 - 5.2e-07 29.1 0.3 2.4e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 Kelch motif AAA_6 PF12774.7 EGB03332.1 - 1.6e-133 444.8 0.0 1.1e-132 441.9 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 EGB03332.1 - 2.6e-90 302.3 0.0 6e-90 301.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 EGB03332.1 - 5.3e-88 295.8 0.2 1.3e-87 294.6 0.0 1.8 2 0 0 2 2 1 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGB03332.1 - 4.3e-75 251.6 0.0 1.3e-74 250.1 0.0 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 EGB03332.1 - 5.6e-74 249.1 0.0 1.2e-73 248.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 EGB03332.1 - 3.2e-70 236.9 5.7 5.5e-70 236.1 5.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 EGB03332.1 - 6.7e-67 224.5 0.0 6.5e-61 205.0 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB03332.1 - 1.4e-45 155.1 0.0 2.7e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB03332.1 - 9.3e-33 112.8 0.0 1.3e-31 109.2 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGB03332.1 - 6.5e-19 68.3 0.8 2e-18 66.7 0.8 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGB03332.1 - 1.5e-15 57.4 0.0 0.0002 21.3 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGB03332.1 - 3e-15 56.2 0.1 1.6e-14 53.9 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 EGB03332.1 - 6.2e-10 39.5 0.1 0.1 12.9 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 EGB03332.1 - 3.2e-09 37.4 1.3 0.063 13.7 0.0 5.8 5 0 0 5 5 4 2 AAA ATPase domain AAA PF00004.29 EGB03332.1 - 4.7e-09 36.8 0.9 0.18 12.3 0.0 4.7 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGB03332.1 - 1.8e-07 31.8 0.1 0.66 10.5 0.0 4.8 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 EGB03332.1 - 1.7e-06 28.3 0.9 0.11 12.7 0.0 5.1 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 EGB03332.1 - 2.3e-05 25.0 1.4 1.3 9.6 0.0 5.2 5 0 0 5 5 4 1 ABC transporter T2SSE PF00437.20 EGB03332.1 - 3.3e-05 23.1 0.1 0.0027 16.8 0.0 3.4 4 0 0 4 4 3 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 EGB03332.1 - 8.6e-05 22.7 0.2 0.37 10.9 0.0 4.3 4 0 0 4 4 4 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 EGB03332.1 - 0.00019 21.2 0.0 1.9 8.1 0.0 3.7 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_30 PF13604.6 EGB03332.1 - 0.00024 20.9 5.9 0.75 9.5 0.0 4.9 5 0 0 5 5 4 1 AAA domain TsaE PF02367.17 EGB03332.1 - 0.00053 20.0 0.1 2.3 8.2 0.0 3.8 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGB03332.1 - 0.00054 20.3 0.1 14 6.1 0.0 4.0 3 0 0 3 3 3 0 RNA helicase Rad17 PF03215.15 EGB03332.1 - 0.00062 19.7 0.1 3.4 7.5 0.0 3.3 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_29 PF13555.6 EGB03332.1 - 0.0013 18.4 0.0 8.4 6.2 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EGB03332.1 - 0.002 17.9 0.0 0.72 9.6 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 EGB03332.1 - 0.002 18.5 0.5 2.7 8.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EGB03332.1 - 0.0041 16.9 0.0 7.8 6.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGB03332.1 - 0.0059 16.5 0.0 3.4 7.5 0.0 3.0 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 EGB03332.1 - 0.011 14.9 0.0 2.7 7.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ORC6 PF05460.13 EGB03332.1 - 0.027 13.8 0.0 0.064 12.5 0.0 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NACHT PF05729.12 EGB03332.1 - 0.035 14.0 0.6 27 4.7 0.0 4.2 4 0 0 4 4 4 0 NACHT domain AAA_25 PF13481.6 EGB03332.1 - 0.066 12.8 2.6 1.9 8.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 EGB03332.1 - 0.15 11.4 3.5 11 5.4 0.0 3.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Bap31_Bap29_C PF18035.1 EGB03332.1 - 0.33 11.0 3.8 0.44 10.6 1.8 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain AAA_11 PF13086.6 EGB03332.1 - 1.5 8.6 7.5 1.3 8.7 0.0 4.1 5 0 0 5 5 4 0 AAA domain Snapin_Pallidin PF14712.6 EGB03332.1 - 8.7 6.8 9.5 4 7.9 2.5 3.9 3 0 0 3 3 2 0 Snapin/Pallidin LIN52 PF10044.9 EGB03333.1 - 0.0075 17.0 0.1 56 4.5 0.0 3.6 3 0 0 3 3 3 3 Retinal tissue protein Toxin_4 PF00706.17 EGB03334.1 - 0.017 15.5 0.4 0.055 13.9 0.4 1.8 1 0 0 1 1 1 0 Anenome neurotoxin DHDPS PF00701.22 EGB03335.1 - 0.043 12.5 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family MlaD PF02470.20 EGB03335.1 - 0.066 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 MlaD protein LRR_6 PF13516.6 EGB03336.1 - 1e-09 37.7 20.8 0.18 12.0 0.1 6.4 6 0 0 6 6 6 6 Leucine Rich repeat LRR_4 PF12799.7 EGB03336.1 - 1.5 9.4 21.8 1.1 9.7 1.0 4.9 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3645 PF12359.8 EGB03337.1 - 1.7e-15 56.1 0.1 3.9e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Rad51 PF08423.11 EGB03338.1 - 0.022 14.0 0.5 0.07 12.4 0.0 1.8 2 0 0 2 2 2 0 Rad51 Glyco_hydro_92 PF07971.12 EGB03339.1 - 4.1e-98 329.3 0.0 5e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGB03339.1 - 3.7e-16 59.8 0.2 1.9e-15 57.4 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_transf_15 PF01793.16 EGB03339.1 - 4.3e-11 42.6 0.0 8.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Methyltransf_32 PF13679.6 EGB03340.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB03340.1 - 0.026 14.1 0.7 0.047 13.2 0.7 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB03340.1 - 0.028 15.1 0.9 0.19 12.5 0.4 2.8 2 0 0 2 2 2 0 Methyltransferase domain TPR_2 PF07719.17 EGB03340.1 - 1.6 9.1 13.0 0.14 12.4 2.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CAP_N PF01213.19 EGB03340.1 - 2.3 7.6 2.9 5.6 6.4 2.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Inhibitor_I29 PF08246.12 EGB03341.1 - 3e-10 40.4 0.0 4.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 EGB03341.1 - 1.1e-08 35.5 0.1 1.4e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 EGB03342.1 - 1.1e-24 87.8 0.1 1.2e-24 87.7 0.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB03342.1 - 0.016 14.0 0.2 0.016 14.0 0.2 1.0 1 0 0 1 1 1 0 Peptidase C1-like family Ribosomal_L29e PF01779.17 EGB03343.1 - 1.8e-15 56.9 4.4 2.4e-15 56.6 4.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family MutL_C PF08676.11 EGB03344.1 - 8.4e-27 93.8 0.0 1.6e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EGB03344.1 - 5.4e-18 64.8 0.0 8.6e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGB03344.1 - 1.5e-10 41.0 0.0 2.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGB03344.1 - 2.2e-05 24.9 0.0 5.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_transf_64 PF09258.10 EGB03345.1 - 2.1e-55 187.7 0.0 2.5e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain AAA_33 PF13671.6 EGB03345.1 - 0.09 12.9 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain RCC1 PF00415.18 EGB03346.1 - 3.5e-29 101.2 8.5 1.7e-14 54.2 0.0 3.3 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB03346.1 - 4e-17 61.5 13.0 1.9e-09 37.1 0.9 3.2 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat tRNA-synt_1 PF00133.22 EGB03347.1 - 3.2e-211 702.7 0.0 4.1e-211 702.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGB03347.1 - 2.1e-21 76.5 0.0 5.2e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGB03347.1 - 8e-13 47.9 0.5 0.00038 19.3 0.1 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGB03347.1 - 0.0052 16.2 0.0 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain HEAT_EZ PF13513.6 EGB03348.1 - 2.1e-16 60.0 2.2 1.4e-09 38.2 0.0 6.4 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EGB03348.1 - 1.4e-11 43.6 21.4 0.0041 17.3 0.0 9.1 10 0 0 10 10 10 4 HEAT repeat IBN_N PF03810.19 EGB03348.1 - 6.1e-09 35.7 0.7 1.2e-07 31.5 0.4 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EGB03348.1 - 5e-05 23.8 4.1 0.039 14.6 0.1 5.6 4 2 3 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGB03348.1 - 0.00052 19.7 0.2 0.014 15.0 0.1 3.1 2 1 0 2 2 2 1 CLASP N terminal Arm PF00514.23 EGB03348.1 - 0.00065 19.7 1.1 1.9 8.7 0.0 4.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB03348.1 - 0.00094 19.5 11.6 0.16 12.4 0.4 6.1 4 2 4 8 8 7 1 HEAT repeats Cnd1 PF12717.7 EGB03348.1 - 0.0028 17.7 0.7 0.083 12.9 0.0 3.5 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TetR_C_25 PF17933.1 EGB03348.1 - 0.028 14.7 0.0 0.11 12.8 0.0 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Radial_spoke_3 PF06098.11 EGB03348.1 - 0.51 9.6 6.5 0.056 12.7 0.9 2.2 3 0 0 3 3 3 0 Radial spoke protein 3 Peptidase_C48 PF02902.19 EGB03350.1 - 1.6e-29 103.3 0.0 2.4e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain UCR_UQCRX_QCR9 PF05365.12 EGB03351.1 - 0.092 12.7 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like MBD PF01429.19 EGB03352.1 - 0.00035 20.2 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyl-CpG binding domain Hemerythrin PF01814.23 EGB03352.1 - 0.88 10.2 5.5 0.58 10.8 0.2 3.2 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain Dpy-30 PF05186.13 EGB03353.1 - 0.027 14.2 0.2 0.095 12.4 0.2 2.0 1 1 0 1 1 1 0 Dpy-30 motif ketoacyl-synt PF00109.26 EGB03354.1 - 8.1e-23 81.3 3.2 1.1e-22 80.8 3.2 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03354.1 - 1.4e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EGB03354.1 - 0.088 12.7 0.6 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PS-DH PF14765.6 EGB03355.1 - 1.8e-06 27.4 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PPR_2 PF13041.6 EGB03357.1 - 0.00091 19.4 0.2 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 EGB03357.1 - 0.015 15.5 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 PPR repeat zf-C2H2_7 PF15269.6 EGB03357.1 - 1.7 8.8 10.2 3.5 7.8 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger DUF2695 PF10905.8 EGB03358.1 - 0.078 13.2 1.0 2.5 8.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) Corona_3 PF04694.12 EGB03358.1 - 0.1 12.9 0.2 0.23 11.8 0.2 1.5 1 0 0 1 1 1 0 Coronavirus ORF3 protein Bowman-Birk_leg PF00228.20 EGB03359.1 - 0.0024 18.2 0.4 53 4.3 0.0 4.2 3 0 0 3 3 3 0 Bowman-Birk serine protease inhibitor family Tir_receptor_M PF03549.14 EGB03359.1 - 0.14 12.5 0.0 1.8e+02 2.5 0.0 3.5 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) intimin-binding domain Metallothio_Euk PF12749.7 EGB03359.1 - 0.46 10.7 18.9 4 7.7 5.5 2.7 2 0 0 2 2 2 0 Eukaryotic metallothionein STOP PF05217.12 EGB03359.1 - 1.4 9.2 7.1 15 6.0 0.8 2.6 2 0 0 2 2 2 0 STOP protein C2 PF00168.30 EGB03360.1 - 0.13 12.6 0.1 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 C2 domain HNH_3 PF13392.6 EGB03361.1 - 2.2e-15 56.2 1.1 3.3e-15 55.6 1.1 1.3 1 0 0 1 1 1 1 HNH endonuclease NUMOD4 PF07463.11 EGB03361.1 - 8.3e-09 35.5 0.3 2.5e-08 34.0 0.1 2.0 2 0 0 2 2 2 1 NUMOD4 motif AP2 PF00847.20 EGB03361.1 - 0.0093 16.2 0.4 0.026 14.7 0.4 1.8 1 0 0 1 1 1 1 AP2 domain Phage_antitermQ PF06530.12 EGB03361.1 - 0.033 14.1 0.1 6.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Phage antitermination protein Q zf-C3HC4_4 PF15227.6 EGB03362.1 - 5.1 7.3 22.0 1.7 8.9 1.8 4.5 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING ABC1 PF03109.16 EGB03363.1 - 8.3e-15 55.0 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGB03364.1 - 5.1e-05 22.8 0.0 8.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC_tran PF00005.27 EGB03366.1 - 5e-22 78.9 0.0 7.9e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGB03366.1 - 4.1e-05 23.2 0.1 0.00011 21.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB03366.1 - 0.00012 22.0 0.2 0.31 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB03366.1 - 0.00046 20.1 0.2 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGB03366.1 - 0.0011 19.3 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGB03366.1 - 0.0043 17.6 0.0 0.0065 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB03366.1 - 0.03 14.7 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGB03366.1 - 0.053 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGB03366.1 - 0.086 12.3 0.0 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 EGB03366.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EGB03366.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain rve PF00665.26 EGB03367.1 - 2.4e-16 60.0 0.0 5.9e-16 58.7 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EGB03367.1 - 1.5e-13 50.6 1.4 2.8e-13 49.8 1.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_3 PF13358.6 EGB03367.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease SHOCT PF09851.9 EGB03368.1 - 8e-13 47.7 0.2 0.022 14.5 0.0 3.9 3 0 0 3 3 3 3 Short C-terminal domain GvpG PF05120.12 EGB03368.1 - 0.00078 19.4 1.0 22 5.2 0.0 3.9 4 0 0 4 4 4 3 Gas vesicle protein G Trypan_PARP PF05887.11 EGB03368.1 - 0.00084 19.3 28.6 0.00084 19.3 28.6 3.5 4 0 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) DUF1145 PF06611.12 EGB03368.1 - 2.2 8.3 3.5 29 4.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) WDCP PF15390.6 EGB03368.1 - 4.2 5.6 7.8 6.5 5.0 7.8 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MutS_III PF05192.18 EGB03369.1 - 5.7e-14 52.8 2.5 7.8e-14 52.3 0.1 2.2 2 0 0 2 2 2 1 MutS domain III SWIM PF04434.17 EGB03372.1 - 0.0085 15.7 0.4 0.0085 15.7 0.4 2.2 2 0 0 2 2 2 1 SWIM zinc finger Sulfotransfer_3 PF13469.6 EGB03373.1 - 0.28 11.5 5.1 0.88 9.9 0.0 3.2 3 0 0 3 3 3 0 Sulfotransferase family Rad60-SLD PF11976.8 EGB03375.1 - 8.6e-10 38.3 0.0 9.9e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGB03375.1 - 5e-06 26.2 0.0 5.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Peptidase_M17 PF00883.21 EGB03376.1 - 2.8e-100 335.6 0.1 3.4e-100 335.3 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF1618 PF07762.14 EGB03377.1 - 0.093 13.3 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1618) Sporozoite_P67 PF05642.11 EGB03377.1 - 3.8 5.5 15.9 7.8 4.4 15.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen OTU PF02338.19 EGB03378.1 - 1.2e-11 45.2 0.0 2.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease TPR_2 PF07719.17 EGB03378.1 - 0.00018 21.4 9.1 0.007 16.4 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Peptidase_C65 PF10275.9 EGB03378.1 - 0.0013 18.3 0.0 0.52 9.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain TPR_1 PF00515.28 EGB03378.1 - 0.0063 16.3 4.3 0.2 11.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGB03378.1 - 0.015 15.0 0.3 0.037 13.6 0.3 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) MIT PF04212.18 EGB03378.1 - 0.032 14.3 0.4 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 EGB03378.1 - 0.13 12.4 4.9 0.11 12.7 2.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB03378.1 - 0.63 10.6 5.6 0.73 10.4 2.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_32 PF13679.6 EGB03379.1 - 1.2e-10 41.7 0.1 0.00067 19.7 0.2 2.4 2 0 0 2 2 2 2 Methyltransferase domain DUF2563 PF10817.8 EGB03379.1 - 3.1 8.4 6.6 5.3 7.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2563) LSM PF01423.22 EGB03380.1 - 1.7e-17 62.9 0.1 2.2e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGB03380.1 - 0.0024 17.5 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Hfq protein HydF_dimer PF18128.1 EGB03380.1 - 0.097 12.8 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 Hydrogen maturase F dimerization domain WD40 PF00400.32 EGB03381.1 - 1.4e-12 47.9 6.3 0.00062 20.5 0.3 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB03381.1 - 0.00024 21.3 0.0 1.7 9.0 0.0 4.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 EGB03381.1 - 0.00078 19.7 3.1 0.00078 19.7 3.1 4.3 1 1 2 4 4 4 2 Autophagy protein 16 (ATG16) Wyosine_form PF08608.12 EGB03381.1 - 0.085 13.2 1.4 10 6.6 0.4 2.8 2 0 0 2 2 2 0 Wyosine base formation PPTA PF01239.22 EGB03382.1 - 6.6e-34 114.6 6.5 5.7e-10 38.6 0.1 4.4 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat HEAT PF02985.22 EGB03382.1 - 0.14 12.4 0.1 6 7.4 0.1 3.3 4 0 0 4 4 4 0 HEAT repeat DUF4219 PF13961.6 EGB03382.1 - 0.15 11.8 7.9 1.1 9.0 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) FMN_red PF03358.15 EGB03383.1 - 2.9e-22 79.1 0.0 4.3e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Pkinase PF00069.25 EGB03384.1 - 9.6e-36 123.5 0.0 1.8e-35 122.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03384.1 - 2.1e-23 82.9 0.0 3.8e-23 82.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase CCDC53 PF10152.9 EGB03385.1 - 2.1e-93 310.8 33.8 8.5e-13 49.0 0.1 8.7 8 1 0 8 8 8 7 Subunit CCDC53 of WASH complex FH2 PF02181.23 EGB03385.1 - 4.4e-44 151.1 0.0 5.9e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGB03385.1 - 2.1e-08 33.9 0.0 4.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain HrpJ PF07201.11 EGB03385.1 - 0.013 15.9 1.7 0.13 12.6 0.3 2.7 2 0 0 2 2 2 0 HrpJ-like domain Dynein_attach_N PF15867.5 EGB03385.1 - 0.04 13.9 1.0 0.29 11.1 0.1 2.8 3 0 0 3 3 3 0 Dynein attachment factor N-terminus RPAP1_N PF08621.10 EGB03385.1 - 0.15 11.8 2.1 1.6e+02 2.2 0.0 4.3 4 0 0 4 4 4 0 RPAP1-like, N-terminal DUF438 PF04282.13 EGB03385.1 - 0.24 11.4 12.7 1.3e+02 2.6 0.0 6.9 7 0 0 7 7 7 0 Family of unknown function (DUF438) PDEase_I PF00233.19 EGB03386.1 - 4e-69 233.0 0.0 4.9e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HAD_2 PF13419.6 EGB03387.1 - 1.8e-25 90.0 0.0 2.2e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB03387.1 - 5e-17 62.9 0.1 4.4e-16 59.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB03387.1 - 2.9e-07 31.1 0.0 4.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB03387.1 - 0.00037 20.5 0.2 0.0008 19.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like PSY3 PF16836.5 EGB03387.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description UQ_con PF00179.26 EGB03388.1 - 2.6e-27 95.2 0.0 2.9e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA PF00092.28 EGB03389.1 - 0.0039 17.5 0.0 0.0087 16.3 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VCBS PF13517.6 EGB03390.1 - 8.5e-61 202.4 134.0 2.4e-09 37.6 8.1 14.0 2 2 11 13 13 13 13 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Laminin_G_3 PF13385.6 EGB03390.1 - 5e-29 101.4 5.7 5.8e-16 59.0 0.5 6.3 7 1 0 7 7 7 2 Concanavalin A-like lectin/glucanases superfamily Bromodomain PF00439.25 EGB03390.1 - 3.5e-09 36.6 0.0 6.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.32 EGB03390.1 - 2.1e-07 31.5 35.8 0.00013 22.7 0.1 8.9 12 0 0 12 12 12 3 WD domain, G-beta repeat Laminin_G_2 PF02210.24 EGB03390.1 - 0.00035 21.1 0.0 1 10.0 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Pentaxin PF00354.17 EGB03390.1 - 0.0086 15.8 0.0 3.3 7.3 0.0 2.9 2 1 0 2 2 2 2 Pentaxin family Dockerin_1 PF00404.18 EGB03390.1 - 0.016 15.3 84.4 0.2 11.8 6.6 11.8 7 3 5 12 12 12 0 Dockerin type I domain PQQ_3 PF13570.6 EGB03390.1 - 0.71 10.4 10.0 7.5 7.2 0.3 6.4 5 0 0 5 5 5 0 PQQ-like domain DOT1 PF08123.13 EGB03392.1 - 2.6e-05 23.9 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 ImpA_N PF06812.12 EGB03392.1 - 0.00012 22.1 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 ImpA, N-terminal, type VI secretion system REJ PF02010.15 EGB03393.1 - 1.3e-43 149.5 0.0 3.3e-40 138.3 0.0 2.2 1 1 1 2 2 2 2 REJ domain Laminin_G_3 PF13385.6 EGB03393.1 - 1e-20 74.4 1.9 1e-20 74.4 1.9 2.8 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily F5_F8_type_C PF00754.25 EGB03393.1 - 3.1e-07 30.6 2.1 5.9e-07 29.6 0.3 2.2 2 0 0 2 2 2 1 F5/8 type C domain Peptidase_M18 PF02127.15 EGB03394.1 - 1.8e-129 432.3 0.0 2.1e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGB03394.1 - 1.4e-07 30.8 0.1 0.00043 19.4 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Cupin_8 PF13621.6 EGB03395.1 - 9.8e-14 51.7 0.0 7.3e-13 48.8 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Trefoil PF00088.18 EGB03395.1 - 0.0066 16.3 32.6 5.7 6.9 0.2 7.1 7 0 0 7 7 7 6 Trefoil (P-type) domain Cupin_4 PF08007.12 EGB03395.1 - 0.011 15.2 0.0 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Cupin superfamily protein Macro PF01661.21 EGB03395.1 - 0.46 10.5 2.6 25 4.9 0.0 4.2 5 0 0 5 5 5 0 Macro domain SHIPPO-rpt PF07004.12 EGB03396.1 - 0.0054 17.6 7.9 0.0067 17.3 0.7 3.2 2 1 0 2 2 2 1 Sperm-tail PG-rich repeat Pkinase PF00069.25 EGB03397.1 - 5.5e-11 42.3 0.0 8.5e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03397.1 - 1.8e-08 34.0 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB03397.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CesT PF05932.13 EGB03397.1 - 0.057 13.5 0.3 0.72 10.0 0.1 2.4 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family DUF4200 PF13863.6 EGB03398.1 - 9.3e-05 22.8 1.6 9.3e-05 22.8 1.6 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Gp-FAR-1 PF05823.12 EGB03398.1 - 0.042 14.2 8.6 0.039 14.3 3.0 2.2 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CK2S PF15011.6 EGB03398.1 - 0.078 12.9 4.7 0.18 11.7 0.7 2.5 1 1 2 3 3 3 0 Casein Kinase 2 substrate bZIP_1 PF00170.21 EGB03398.1 - 0.094 12.8 0.3 0.094 12.8 0.3 3.1 3 0 0 3 3 3 0 bZIP transcription factor DUF4349 PF14257.6 EGB03398.1 - 1.6 8.1 5.0 0.33 10.4 1.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Sipho_Gp157 PF05565.11 EGB03398.1 - 2.5 8.1 11.1 0.092 12.8 4.6 1.9 2 0 0 2 2 2 0 Siphovirus Gp157 DUF334 PF03904.13 EGB03398.1 - 3.4 7.2 9.6 1.7 8.1 7.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF334) DUF5082 PF16888.5 EGB03398.1 - 5.5 7.3 14.9 14 6.0 6.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Pkinase PF00069.25 EGB03400.1 - 6.6e-12 45.3 0.0 2.2e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03400.1 - 7.2e-10 38.6 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.28 EGB03400.1 - 1.5e-07 32.1 0.0 3.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB03400.1 - 0.0025 18.0 0.0 0.043 14.0 0.0 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Kinase-like PF14531.6 EGB03400.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like C2 PF00168.30 EGB03400.1 - 0.11 12.8 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 C2 domain Glyco_transf_64 PF09258.10 EGB03401.1 - 2.4e-18 66.3 0.0 5e-18 65.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain EF-hand_6 PF13405.6 EGB03402.1 - 0.0041 16.9 0.0 0.9 9.6 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EGB03402.1 - 0.018 15.5 0.1 0.15 12.6 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EGB03402.1 - 0.023 14.3 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EGB03402.1 - 0.16 11.5 0.0 23 4.7 0.0 2.5 2 0 0 2 2 2 0 EF hand Ribosomal_60s PF00428.19 EGB03403.1 - 1.2 9.8 9.0 2 9.1 9.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein TOBE_3 PF12857.7 EGB03404.1 - 0.016 15.1 1.0 3.4 7.7 0.2 3.0 1 1 1 2 2 2 0 TOBE-like domain Phage_GP20 PF06810.11 EGB03404.1 - 0.11 12.2 5.1 3.2 7.6 0.0 3.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 Bombinin PF05298.11 EGB03404.1 - 3.4 7.4 9.6 0.77 9.4 1.1 3.4 3 0 0 3 3 3 0 Bombinin SET PF00856.28 EGB03405.1 - 0.046 14.1 0.0 0.48 10.8 0.0 2.6 2 2 0 2 2 2 0 SET domain NADHdh-2_N PF12155.8 EGB03406.1 - 0.083 13.3 0.3 0.15 12.5 0.3 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal Pkinase PF00069.25 EGB03407.1 - 5.9e-53 179.9 0.0 7.4e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03407.1 - 2e-44 151.9 0.0 3e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB03407.1 - 2.7e-05 23.1 0.0 4.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB03407.1 - 0.00022 20.6 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB03407.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB03407.1 - 0.095 11.6 0.1 0.21 10.5 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Ion_trans PF00520.31 EGB03408.1 - 7.7e-24 84.3 9.2 1.3e-23 83.5 9.1 1.4 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGB03408.1 - 0.017 13.8 5.0 0.017 13.8 3.5 1.6 1 1 1 2 2 2 0 Polycystin cation channel Chromate_transp PF02417.15 EGB03408.1 - 0.13 12.4 3.7 0.056 13.6 1.8 1.4 2 0 0 2 2 2 0 Chromate transporter NDK PF00334.19 EGB03409.1 - 3.2e-33 114.6 0.0 2.4e-24 85.9 0.0 2.6 3 0 0 3 3 3 2 Nucleoside diphosphate kinase TRAPP PF04051.16 EGB03411.1 - 1.6e-35 122.0 0.0 1.8e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DEK_C PF08766.11 EGB03413.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain UvrA_DNA-bind PF17755.1 EGB03413.1 - 0.096 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 UvrA DNA-binding domain SET PF00856.28 EGB03414.1 - 2.2e-11 44.5 0.0 6.5e-11 42.9 0.0 1.8 2 1 0 2 2 2 1 SET domain RCC1 PF00415.18 EGB03415.1 - 5.1e-42 142.3 23.1 3.5e-13 49.9 0.3 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB03415.1 - 3.6e-23 80.8 25.9 1.8e-08 34.0 2.1 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat zf-UBR PF02207.20 EGB03415.1 - 0.02 15.1 6.1 0.069 13.3 6.1 1.9 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Ribosomal_L10 PF00466.20 EGB03416.1 - 3.4e-21 75.3 0.1 7.7e-21 74.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGB03416.1 - 3.4e-20 71.8 0.1 1.1e-19 70.2 0.1 1.9 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EGB03416.1 - 6.2e-09 36.3 4.1 1.1e-08 35.6 4.1 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_34 PF05637.12 EGB03417.1 - 0.022 14.5 0.9 0.33 10.7 0.9 2.4 1 1 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family GlcNAc PF11397.8 EGB03418.1 - 3.2e-41 142.0 0.1 1.7e-27 96.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Hydrolase_4 PF12146.8 EGB03419.1 - 1.5e-12 47.3 0.0 2.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGB03419.1 - 1.5e-06 28.0 0.0 2.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGB03419.1 - 4.1e-05 24.3 2.1 4.8e-05 24.1 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB03419.1 - 7.2e-05 22.6 0.3 0.00026 20.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold 7TM_GPCR_Sru PF10322.9 EGB03419.1 - 0.49 9.7 2.8 0.77 9.0 2.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF1600 PF07667.11 EGB03421.1 - 0.027 14.6 1.4 0.042 14.1 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) DUF5562 PF17717.1 EGB03421.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5562) Acyl_transf_3 PF01757.22 EGB03422.1 - 3.2e-11 42.9 24.4 2.2e-10 40.1 15.8 2.1 2 0 0 2 2 2 2 Acyltransferase family Cytochrom_B_N_2 PF13631.6 EGB03422.1 - 0.032 14.3 1.9 0.037 14.0 0.3 1.9 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Pan3_PK PF18101.1 EGB03423.1 - 6e-40 136.4 0.0 1e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGB03423.1 - 3.8e-05 23.2 0.0 7.9e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain TPR_2 PF07719.17 EGB03424.1 - 0.00039 20.3 0.1 0.00094 19.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat SHOCT PF09851.9 EGB03424.1 - 0.00049 19.7 0.8 0.001 18.7 0.8 1.6 1 0 0 1 1 1 1 Short C-terminal domain TPR_1 PF00515.28 EGB03424.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB03424.1 - 0.019 14.6 0.2 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 TPR repeat Bromodomain PF00439.25 EGB03425.1 - 8.4e-14 51.4 0.0 1.8e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain MBD PF01429.19 EGB03425.1 - 4.4e-05 23.1 0.0 9.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain DDT PF02791.17 EGB03425.1 - 0.057 13.7 0.0 0.26 11.6 0.0 2.2 1 1 0 1 1 1 0 DDT domain WSD PF15613.6 EGB03425.1 - 0.096 13.2 0.2 0.93 10.0 0.2 2.5 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WW PF00397.26 EGB03426.1 - 0.0011 19.0 0.9 0.0011 19.0 0.9 3.4 3 0 0 3 3 3 1 WW domain Atx10homo_assoc PF09759.9 EGB03426.1 - 0.077 13.0 1.2 1.7 8.7 0.1 3.3 2 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RMI1_C PF16099.5 EGB03426.1 - 0.1 12.4 3.6 1 9.2 0.2 2.9 2 0 0 2 2 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold APG9 PF04109.16 EGB03427.1 - 2.5e-141 472.0 2.8 3e-141 471.7 2.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 GFD1 PF17331.2 EGB03428.1 - 3.6e-05 23.8 4.1 0.00021 21.4 4.1 2.4 1 0 0 1 1 1 1 GFD1 mRNA transport factor NPV_P10 PF05531.12 EGB03428.1 - 0.0028 18.1 7.1 0.24 11.9 4.3 3.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 EGB03428.1 - 0.06 12.9 33.2 0.1 12.2 2.4 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain EGF_2 PF07974.13 EGB03430.1 - 2.7e-14 53.2 53.3 5.5e-05 23.4 3.5 5.3 4 1 0 4 4 4 4 EGF-like domain hEGF PF12661.7 EGB03430.1 - 0.0052 17.4 1.7 0.0052 17.4 1.7 6.1 6 0 0 6 6 6 1 Human growth factor-like EGF EGF PF00008.27 EGB03430.1 - 0.02 15.2 44.3 0.18 12.2 0.9 6.1 6 1 0 6 6 6 0 EGF-like domain Laminin_EGF PF00053.24 EGB03430.1 - 0.071 13.3 43.0 0.5 10.5 8.9 4.5 3 1 1 4 4 4 0 Laminin EGF domain DSPc PF00782.20 EGB03431.1 - 8.7e-21 74.1 0.6 9.8e-21 74.0 0.6 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB03431.1 - 0.00024 20.8 0.1 0.00026 20.6 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGB03431.1 - 0.012 15.9 0.1 0.015 15.6 0.1 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EGB03431.1 - 0.032 14.3 0.1 0.041 14.0 0.1 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate Arm PF00514.23 EGB03432.1 - 1.9e-29 100.8 19.9 1.2e-09 37.9 0.0 8.6 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGB03432.1 - 1.6e-19 68.3 10.6 2.2e-05 24.3 0.0 7.8 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 EGB03432.1 - 1.8e-15 57.0 14.7 7.8e-05 23.0 0.1 5.0 3 2 2 5 5 5 5 HEAT repeats Cnd1 PF12717.7 EGB03432.1 - 4.8e-13 49.5 2.4 0.002 18.2 0.2 4.6 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGB03432.1 - 1.5e-12 47.7 16.2 0.001 19.5 0.2 6.8 6 1 1 7 7 7 6 HEAT-like repeat Adaptin_N PF01602.20 EGB03432.1 - 1.4e-09 37.1 2.6 0.0014 17.3 0.2 4.0 2 2 1 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.11 EGB03432.1 - 1.4e-08 34.8 0.1 0.048 13.4 0.0 3.8 2 1 1 3 3 3 2 DNA alkylation repair enzyme CLASP_N PF12348.8 EGB03432.1 - 6.8e-07 29.1 0.4 0.1 12.2 0.0 3.4 3 1 0 3 3 3 2 CLASP N terminal Atx10homo_assoc PF09759.9 EGB03432.1 - 7e-06 26.0 1.2 0.1 12.7 0.1 4.4 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain CHASE6_C PF17150.4 EGB03432.1 - 1.6e-05 25.5 0.7 16 6.3 0.0 5.9 5 1 0 5 5 5 0 C-terminal domain of two-partite extracellular sensor domain Proteasom_PSMB PF10508.9 EGB03432.1 - 5.4e-05 21.9 8.1 0.0016 17.0 0.2 3.8 2 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 EGB03432.1 - 0.0028 17.7 0.6 14 5.8 0.1 4.2 3 2 2 5 5 5 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 EGB03432.1 - 0.011 16.3 0.2 0.58 10.8 0.1 3.1 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_UF PF18817.1 EGB03432.1 - 0.014 15.7 0.7 2.2 8.6 0.0 4.1 5 0 0 5 5 4 0 Repeat of uncharacterized protein PH0542 Arm_2 PF04826.13 EGB03432.1 - 0.093 12.2 1.7 6.5 6.1 0.0 3.8 2 1 1 5 5 5 0 Armadillo-like RTP1_C1 PF10363.9 EGB03432.1 - 0.28 11.4 2.0 2 8.7 0.0 3.1 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3361 PF11841.8 EGB03432.1 - 0.42 10.5 2.8 13 5.7 0.1 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 EGB03432.1 - 2.8 8.9 17.7 24 6.0 0.1 6.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Tctex-1 PF03645.13 EGB03433.1 - 5.2e-25 87.7 0.6 6.2e-25 87.4 0.6 1.1 1 0 0 1 1 1 1 Tctex-1 family SWIM PF04434.17 EGB03434.1 - 0.0028 17.3 0.5 0.0028 17.3 0.5 2.1 2 0 0 2 2 2 1 SWIM zinc finger ketoacyl-synt PF00109.26 EGB03436.1 - 8.1e-23 81.3 3.2 1.1e-22 80.8 3.2 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03436.1 - 1.4e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EGB03436.1 - 0.088 12.7 0.6 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PS-DH PF14765.6 EGB03437.1 - 2.5e-06 27.0 0.0 4.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EGB03437.1 - 4.3e-06 26.7 0.0 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGB03438.1 - 1.3e-33 116.6 10.3 1.9e-33 116.1 10.3 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03438.1 - 3.7e-07 30.2 0.1 1e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB03438.1 - 0.0012 18.2 1.5 0.0017 17.7 1.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGB03438.1 - 0.74 9.7 5.2 11 6.0 5.2 2.4 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 EGB03439.1 - 2e-26 92.9 0.1 2.2e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HPTransfase PF10090.9 EGB03440.1 - 0.015 15.1 0.5 0.15 11.9 0.2 2.3 1 1 1 2 2 2 0 Histidine phosphotransferase C-terminal domain PP-binding PF00550.25 EGB03440.1 - 0.058 13.8 0.1 0.7 10.3 0.0 2.4 1 1 1 2 2 2 0 Phosphopantetheine attachment site Peptidase_M56 PF05569.11 EGB03441.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 ECH_1 PF00378.20 EGB03441.1 - 0.028 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase PP-binding PF00550.25 EGB03441.1 - 0.03 14.7 0.3 0.082 13.3 0.3 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site ECH_1 PF00378.20 EGB03442.1 - 1.5e-35 122.7 0.0 1.9e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB03442.1 - 1.6e-10 41.0 0.0 1.6e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PS-DH PF14765.6 EGB03443.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EGB03444.1 - 1.8e-33 116.2 10.4 2.8e-33 115.6 10.4 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03444.1 - 2.9e-06 27.3 0.1 8.1e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SHOCT PF09851.9 EGB03447.1 - 0.0037 16.9 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 Short C-terminal domain PPR_2 PF13041.6 EGB03450.1 - 0.0029 17.8 0.2 2.6 8.3 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 EGB03450.1 - 0.03 14.6 0.0 14 6.2 0.0 2.5 2 0 0 2 2 2 0 PPR repeat DNA_pol_E_B PF04042.16 EGB03452.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Uds1 PF15456.6 EGB03453.1 - 0.53 10.5 12.9 0.11 12.7 7.7 2.4 2 0 0 2 2 2 0 Up-regulated During Septation WDCP PF15390.6 EGB03453.1 - 0.83 8.0 7.9 1.1 7.6 7.9 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PDE4_UCR PF18100.1 EGB03453.1 - 1.8 9.2 8.3 0.99 10.1 5.6 2.0 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) AOX PF01786.17 EGB03455.1 - 0.043 13.4 0.3 0.076 12.6 0.3 1.4 1 0 0 1 1 1 0 Alternative oxidase Glyco_tran_28_C PF04101.16 EGB03456.1 - 0.00025 21.1 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 EGB03456.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Prenyltrans PF00432.21 EGB03457.1 - 0.3 10.9 1.4 7 6.5 0.0 2.6 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat ketoacyl-synt PF00109.26 EGB03460.1 - 8.9e-24 84.4 4.3 9.8e-24 84.3 4.3 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGB03460.1 - 0.068 13.0 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 EGB03461.1 - 8.4e-28 97.4 0.1 9.2e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 EGB03462.1 - 1.5e-23 83.7 2.9 1.8e-23 83.5 2.9 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EGB03462.1 - 0.034 13.5 0.1 0.044 13.1 0.1 1.1 1 0 0 1 1 1 0 Thiolase, N-terminal domain PP-binding PF00550.25 EGB03463.1 - 2.2e-21 76.0 0.5 8.2e-11 42.1 0.2 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 EGB03463.1 - 9.6e-20 71.2 1.2 1.9e-19 70.3 1.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03463.1 - 0.0019 18.2 1.3 0.0046 17.0 1.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB03463.1 - 0.0044 16.4 0.6 0.0076 15.6 0.6 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ECH_1 PF00378.20 EGB03464.1 - 1e-23 84.0 0.0 1.1e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB03464.1 - 2.5e-08 33.8 0.0 3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 EGB03465.1 - 1.2e-21 77.4 3.2 2.2e-21 76.6 3.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03465.1 - 0.0039 17.2 0.2 0.0082 16.2 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_7 PF13241.6 EGB03465.1 - 0.039 14.4 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Biotin_carb_N PF00289.22 EGB03465.1 - 0.089 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain DUF3565 PF12088.8 EGB03467.1 - 0.24 11.4 1.8 2.5 8.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) KA1 PF02149.19 EGB03467.1 - 0.53 10.1 3.2 6.9 6.6 0.9 2.4 2 0 0 2 2 2 0 Kinase associated domain 1 Sdh5 PF03937.16 EGB03469.1 - 1e-22 79.8 0.0 1.2e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase TruB_N PF01509.18 EGB03470.1 - 8.9e-50 168.9 0.0 1.3e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGB03470.1 - 0.00014 21.9 0.1 0.00059 19.9 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Sdh5 PF03937.16 EGB03471.1 - 1e-22 79.8 0.0 1.2e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase TruB_N PF01509.18 EGB03472.1 - 3.8e-24 85.8 0.0 5.5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGB03472.1 - 5.4e-05 23.3 0.0 0.00029 20.9 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain FKBP_C PF00254.28 EGB03473.1 - 1.5e-31 108.5 0.0 8e-22 77.4 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EGB03473.1 - 7.3e-06 25.7 5.0 0.17 12.1 0.7 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB03473.1 - 1.9e-05 24.2 1.7 2.1 8.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB03473.1 - 3.4e-05 24.3 1.4 0.98 10.0 0.1 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB03473.1 - 0.00013 22.1 0.3 0.4 11.2 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB03473.1 - 0.00022 21.2 0.2 0.13 12.4 0.0 2.5 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EGB03473.1 - 0.00031 21.3 2.9 0.022 15.6 1.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB03473.1 - 0.0011 18.5 0.8 2.9 7.7 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 EGB03473.1 - 0.0046 17.2 1.3 0.18 12.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB03473.1 - 0.0061 17.1 0.1 0.65 10.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat M20_dimer PF07687.14 EGB03473.1 - 0.056 13.4 0.1 0.35 10.8 0.0 2.3 3 0 0 3 3 3 0 Peptidase dimerisation domain His_biosynth PF00977.21 EGB03474.1 - 5.6e-36 124.1 0.0 1.9e-35 122.4 0.0 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EGB03474.1 - 0.0048 16.2 0.4 0.01 15.2 0.4 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Ank PF00023.30 EGB03475.1 - 1.5e-14 53.7 0.0 2e-06 28.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGB03475.1 - 2e-14 53.9 0.0 5e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB03475.1 - 4.4e-14 52.4 0.0 1.1e-08 35.2 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB03475.1 - 5.3e-13 47.9 0.0 2.8e-05 24.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGB03475.1 - 2.2e-12 47.2 0.0 1.5e-06 28.6 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) GST_N_5 PF18485.1 EGB03475.1 - 0.085 13.2 0.1 0.42 11.0 0.0 2.0 2 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain U-box PF04564.15 EGB03476.1 - 3e-17 62.5 0.0 3.3e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB03476.1 - 2.8e-05 23.8 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGB03476.1 - 0.0005 20.0 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EGB03476.1 - 0.0028 17.8 0.0 0.0032 17.6 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 EGB03476.1 - 0.02 14.2 0.0 0.022 14.1 0.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger LRR_6 PF13516.6 EGB03478.1 - 2e-07 30.5 15.0 0.23 11.6 0.0 6.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 EGB03478.1 - 0.00093 19.5 0.0 4.7 7.8 0.0 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB03478.1 - 0.019 15.4 3.7 3.1 8.7 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat Mito_carr PF00153.27 EGB03479.1 - 3.3e-47 158.4 0.2 2.3e-15 56.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein RIO1 PF01163.22 EGB03480.1 - 4.2e-39 134.1 0.0 5.9e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EGB03480.1 - 2.3e-30 104.6 0.0 3.9e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EGB03480.1 - 1.1e-05 25.5 0.2 0.0014 18.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EGB03480.1 - 0.00025 20.5 0.4 0.17 11.2 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 EGB03480.1 - 0.012 15.0 0.0 0.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGB03480.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase MatE PF01554.18 EGB03481.1 - 3.3e-45 153.6 7.8 9.4e-28 96.9 1.3 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGB03481.1 - 3.9e-05 23.8 1.6 3.9e-05 23.8 1.6 3.7 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Mito_carr PF00153.27 EGB03481.1 - 0.14 12.1 2.0 3.9 7.5 0.1 3.2 3 0 0 3 3 3 0 Mitochondrial carrier protein PGM_PMM_I PF02878.16 EGB03482.1 - 5.6e-20 71.4 0.4 1e-08 34.9 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EGB03482.1 - 1.9e-11 44.0 0.1 5.7e-11 42.4 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EGB03482.1 - 2.1e-08 34.3 0.4 1.1e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Arm PF00514.23 EGB03483.1 - 3.3e-15 55.5 2.1 1.7e-07 31.0 0.4 2.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGB03483.1 - 8.3e-06 26.2 1.4 0.041 14.4 0.3 2.2 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 EGB03483.1 - 0.00014 22.2 0.7 0.00033 21.0 0.5 1.4 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.22 EGB03483.1 - 0.002 18.2 0.3 0.096 13.0 0.1 2.4 2 0 0 2 2 2 1 HEAT repeat Arm_2 PF04826.13 EGB03483.1 - 0.089 12.2 0.0 1.3 8.4 0.0 1.9 1 1 1 2 2 2 0 Armadillo-like CvfB_WH PF17783.1 EGB03484.1 - 4.4e-12 45.6 0.0 6.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 CvfB-like winged helix domain RRM_1 PF00076.22 EGB03484.1 - 9.8e-08 31.7 0.0 2.4e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB03484.1 - 0.032 14.1 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif BUD22 PF09073.10 EGB03485.1 - 0.016 14.6 24.2 0.02 14.2 24.2 1.1 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EGB03485.1 - 5.2 6.7 9.3 1.1 8.9 0.9 2.6 2 1 0 2 2 2 0 FAM176 family PKcGMP_CC PF16808.5 EGB03486.1 - 0.04 13.8 1.3 4.7 7.2 0.1 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S8 PF00082.22 EGB03487.1 - 3.9e-30 105.1 0.8 6.6e-30 104.4 0.8 1.4 1 0 0 1 1 1 1 Subtilase family Sel1 PF08238.12 EGB03488.1 - 1.2e-24 86.2 12.7 1.6e-08 34.9 0.1 4.8 5 1 0 5 5 5 4 Sel1 repeat TPR_12 PF13424.6 EGB03488.1 - 0.019 15.2 1.0 0.019 15.2 1.0 4.0 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB03488.1 - 0.038 13.9 0.3 0.038 13.9 0.3 3.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB03488.1 - 0.098 13.3 12.4 1.9 9.2 0.0 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF1955 PF09205.10 EGB03488.1 - 0.15 11.8 0.1 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) TPR_1 PF00515.28 EGB03488.1 - 0.38 10.6 0.2 0.38 10.6 0.2 4.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB03488.1 - 5.8 7.3 18.0 0.45 10.7 0.3 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_C1 PF00112.23 EGB03489.1 - 4.3e-64 216.6 6.4 6.5e-64 216.0 6.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 EGB03489.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 EGB03489.1 - 0.0077 15.1 2.9 0.6 8.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DHC_N1 PF08385.12 EGB03490.1 - 7.3e-176 586.1 3.4 7.3e-176 586.1 3.4 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EGB03490.1 - 3.5e-142 473.2 0.0 8.6e-142 471.9 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB03490.1 - 4.9e-121 404.6 3.1 4.9e-121 404.6 3.1 4.2 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGB03490.1 - 6.8e-95 317.3 0.0 3.3e-94 315.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGB03490.1 - 4.1e-84 281.1 0.6 1.2e-83 279.6 0.3 2.1 2 0 0 2 2 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 EGB03490.1 - 1.3e-81 274.2 0.6 9.8e-81 271.3 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGB03490.1 - 7.8e-67 224.3 0.2 1.1e-61 207.5 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB03490.1 - 2.9e-52 176.8 0.0 6.5e-52 175.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB03490.1 - 7.8e-43 145.4 0.0 6.8e-42 142.3 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGB03490.1 - 4.7e-35 121.2 17.1 1.4e-25 90.1 14.5 2.8 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EGB03490.1 - 7.9e-22 77.7 0.0 1.8e-06 28.0 0.0 6.5 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGB03490.1 - 2.4e-19 69.7 0.0 1.1e-18 67.6 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGB03490.1 - 7.6e-18 64.6 0.1 2.3e-16 59.8 0.0 3.5 3 0 0 3 3 3 1 AAA+ lid domain AAA_22 PF13401.6 EGB03490.1 - 4.1e-06 27.1 2.8 0.71 10.1 0.0 5.9 6 1 1 7 7 6 1 AAA domain AAA PF00004.29 EGB03490.1 - 5.1e-06 26.9 1.4 0.056 13.9 0.0 5.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB03490.1 - 2.1e-05 25.0 4.9 4 7.8 0.0 5.7 5 1 0 5 5 4 1 AAA ATPase domain T2SSE PF00437.20 EGB03490.1 - 4.8e-05 22.6 0.0 0.34 9.9 0.0 3.5 3 0 0 3 3 3 2 Type II/IV secretion system protein Rad17 PF03215.15 EGB03490.1 - 0.00054 19.9 0.3 0.16 11.9 0.0 3.5 3 0 0 3 3 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGB03490.1 - 0.00063 19.7 3.5 0.25 11.2 0.0 3.7 4 0 0 4 4 3 1 RsgA GTPase AAA_29 PF13555.6 EGB03490.1 - 0.00083 19.0 0.2 3.1 7.6 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGB03490.1 - 0.0086 16.6 0.0 1.8 9.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EGB03490.1 - 0.018 14.8 1.2 22 4.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGB03490.1 - 2 8.9 3.9 45 4.5 0.0 4.7 6 0 0 6 6 3 0 ABC transporter DUF1515 PF07439.11 EGB03490.1 - 2.3 8.3 9.2 11 6.0 0.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) AAA_19 PF13245.6 EGB03490.1 - 7.3 6.9 10.9 1.1e+02 3.2 0.0 5.2 6 0 0 6 6 4 0 AAA domain DUF1995 PF09353.10 EGB03491.1 - 3.4e-44 151.2 0.0 4e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Maf1 PF09174.10 EGB03492.1 - 1.2e-53 181.8 0.0 1.5e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator DUF4378 PF14309.6 EGB03492.1 - 0.065 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) RNA_pol_L_2 PF13656.6 EGB03493.1 - 4.1e-27 93.8 0.0 4.4e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGB03493.1 - 2.3e-06 26.9 0.0 3.4e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1970 PF09301.10 EGB03493.1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) DHDPS PF00701.22 EGB03494.1 - 2.1e-25 89.0 0.0 3.9e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ank_2 PF12796.7 EGB03494.1 - 7e-16 58.6 1.9 4.1e-09 36.9 0.2 3.3 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) CRAL_TRIO PF00650.20 EGB03494.1 - 6.4e-15 55.2 0.0 1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Ank_4 PF13637.6 EGB03494.1 - 1.8e-13 50.7 0.1 0.00013 22.4 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EGB03494.1 - 3.1e-11 42.0 0.1 9.4e-05 21.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB03494.1 - 6.2e-10 38.2 0.2 0.00036 20.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain Ank PF00023.30 EGB03494.1 - 6.6e-10 39.0 8.0 0.013 15.9 1.5 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EGB03494.1 - 7.1e-10 38.3 0.5 0.14 12.8 0.0 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGB03494.1 - 5e-09 36.3 2.7 0.0027 18.0 0.4 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 EGB03494.1 - 9.1e-08 32.4 0.1 2.3e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB03494.1 - 6.9e-07 28.5 0.2 0.019 14.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB03494.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Ribosomal_L23 PF00276.20 EGB03495.1 - 1.1e-15 57.7 2.2 5.5e-15 55.5 2.2 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 SRPRB PF09439.10 EGB03495.1 - 0.03 13.7 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ank_4 PF13637.6 EGB03496.1 - 5.1e-32 109.8 2.8 2e-10 41.0 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB03496.1 - 1.3e-20 73.7 0.0 1.3e-10 41.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB03496.1 - 8.1e-20 70.6 1.1 1.1e-08 35.1 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB03496.1 - 7.2e-18 62.8 0.1 9.8e-07 28.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGB03496.1 - 5.5e-15 55.0 1.0 4.5e-06 26.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat AAA PF00004.29 EGB03497.1 - 5.3e-18 65.7 0.0 9.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGB03497.1 - 1.7e-06 28.1 0.0 4.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB03497.1 - 2.1e-05 25.0 1.0 5.7e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB03497.1 - 0.00015 22.1 0.0 0.00073 19.8 0.0 2.1 3 0 0 3 3 1 1 AAA domain IstB_IS21 PF01695.17 EGB03497.1 - 0.0025 17.5 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 EGB03497.1 - 0.0027 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 EGB03497.1 - 0.0046 16.8 1.8 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGB03497.1 - 0.0059 16.3 0.6 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGB03497.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EGB03497.1 - 0.022 15.3 0.0 0.067 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGB03497.1 - 0.033 14.5 0.1 0.075 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB03497.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB03497.1 - 0.041 14.1 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB03497.1 - 0.044 13.2 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGB03497.1 - 0.051 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EGB03497.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EGB03497.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein RuvB_N PF05496.12 EGB03497.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EGB03497.1 - 0.088 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EGB03497.1 - 0.092 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EGB03497.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 EGB03497.1 - 0.11 13.0 0.0 0.83 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGB03497.1 - 0.11 13.0 0.1 0.36 11.3 0.0 1.9 2 0 0 2 2 1 0 ABC transporter BMC PF00936.19 EGB03497.1 - 0.14 12.2 1.6 0.24 11.4 0.3 2.0 2 0 0 2 2 2 0 BMC domain AAA_6 PF12774.7 EGB03497.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Viral_helicase1 PF01443.18 EGB03497.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF3342 PF11822.8 EGB03498.1 - 1.1e-28 99.3 0.1 1.7e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) CHORD PF04968.12 EGB03498.1 - 0.002 18.8 7.8 0.0042 17.8 7.8 1.5 1 0 0 1 1 1 1 CHORD BTB PF00651.31 EGB03498.1 - 0.0022 18.2 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain GMC_oxred_C PF05199.13 EGB03499.1 - 4e-37 127.9 0.2 6e-37 127.4 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EGB03499.1 - 0.00034 20.1 1.1 0.00044 19.7 0.2 1.7 2 0 0 2 2 2 1 GMC oxidoreductase HAD PF12710.7 EGB03499.1 - 0.061 13.7 0.0 3.7 7.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.19 EGB03500.1 - 1.7e-71 241.0 0.0 2.8e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGB03500.1 - 4e-36 124.7 0.2 9.1e-36 123.5 0.2 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EGB03500.1 - 6.6e-07 28.8 0.1 0.00026 20.3 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RINGv PF12906.7 EGB03500.1 - 2.1e-06 27.8 8.6 3.9e-06 26.9 8.6 1.5 1 0 0 1 1 1 1 RING-variant domain DAO PF01266.24 EGB03500.1 - 4.4e-06 26.5 4.4 0.0016 18.1 2.5 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase DUF179 PF02622.15 EGB03500.1 - 2.6e-05 24.2 0.2 7.9e-05 22.7 0.2 1.8 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 Lycopene_cycl PF05834.12 EGB03500.1 - 0.00034 19.8 0.6 0.00073 18.7 0.6 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGB03500.1 - 0.00075 19.7 3.3 0.0013 18.9 1.2 2.7 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGB03500.1 - 0.00094 18.4 0.2 0.013 14.6 0.5 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGB03500.1 - 0.0042 16.2 2.7 0.0042 16.2 2.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EGB03500.1 - 0.0061 15.9 0.0 0.52 9.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGB03500.1 - 0.0084 15.8 0.5 0.018 14.7 0.5 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EGB03500.1 - 0.009 16.6 0.7 0.034 14.7 0.7 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB03500.1 - 0.0094 14.7 1.3 0.017 13.8 0.7 1.7 2 0 0 2 2 2 1 HI0933-like protein zf-RING_2 PF13639.6 EGB03500.1 - 0.034 14.5 7.7 0.082 13.3 7.7 1.7 1 0 0 1 1 1 0 Ring finger domain FAD_binding_3 PF01494.19 EGB03500.1 - 0.054 12.7 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain PHD PF00628.29 EGB03500.1 - 0.16 11.9 6.6 0.36 10.7 6.6 1.7 1 0 0 1 1 1 0 PHD-finger YjeF_N PF03853.15 EGB03500.1 - 0.16 11.8 1.9 1.5 8.7 0.2 2.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Thi4 PF01946.17 EGB03500.1 - 0.18 11.0 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGB03500.1 - 0.28 11.1 3.2 30 4.6 0.1 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ribosomal_L28 PF00830.19 EGB03501.1 - 1.7e-15 57.0 3.4 2.6e-15 56.3 3.4 1.3 1 0 0 1 1 1 1 Ribosomal L28 family FAM177 PF14774.6 EGB03501.1 - 0.021 15.2 0.1 0.047 14.1 0.1 1.5 1 1 0 1 1 1 0 FAM177 family DUF1744 PF08490.12 EGB03502.1 - 4e-74 249.6 0.0 2.3e-73 247.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGB03502.1 - 3.8e-65 220.2 0.0 5.9e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGB03502.1 - 1.8e-13 50.0 0.6 4.1e-08 32.4 1.8 3.4 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGB03502.1 - 2.1e-06 27.6 0.1 3.9e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGB03502.1 - 0.00055 20.0 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily Erythro_esteras PF05139.14 EGB03503.1 - 3.1e-88 296.9 1.7 3.5e-88 296.7 1.7 1.0 1 0 0 1 1 1 1 Erythromycin esterase dbPDZ_assoc PF16610.5 EGB03504.1 - 0.45 10.8 19.5 15 5.9 0.5 4.4 1 1 3 4 4 4 0 Unstructured region between two PDZ domains on Dlg5 T_cell_tran_alt PF15128.6 EGB03504.1 - 3.2 7.6 16.4 23 4.9 0.3 4.3 1 1 4 5 5 5 0 T-cell leukemia translocation-altered XPG_N PF00752.17 EGB03505.1 - 8.9e-22 77.5 0.0 2.5e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain DNA_methylase PF00145.17 EGB03507.1 - 5.7e-14 52.2 0.0 9.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase ARL2_Bind_BART PF11527.8 EGB03508.1 - 1.7e-17 63.6 0.0 2.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Kinesin PF00225.23 EGB03508.1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain DUF454 PF04304.13 EGB03510.1 - 0.14 12.2 1.0 0.2 11.7 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF454) CENP-T_C PF15511.6 EGB03512.1 - 3.3e-08 33.6 0.0 4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB03512.1 - 0.00046 20.5 0.0 0.00059 20.2 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB03512.1 - 0.0017 18.5 0.1 0.0026 17.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB03512.1 - 0.016 15.5 0.1 0.031 14.5 0.1 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB03512.1 - 0.042 14.2 0.1 0.062 13.7 0.1 1.3 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Glyco_tran_28_C PF04101.16 EGB03513.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 EGB03513.1 - 0.088 11.6 0.2 0.22 10.3 0.1 1.6 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Sulfotransfer_3 PF13469.6 EGB03514.1 - 0.094 13.1 0.1 0.31 11.4 0.0 1.8 1 1 1 2 2 2 0 Sulfotransferase family TMEM189_B_dmain PF10520.9 EGB03515.1 - 1.2e-16 61.3 0.9 1.9e-16 60.7 0.9 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain Apt1 PF10351.9 EGB03516.1 - 2.6 6.8 10.5 3.6 6.3 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 EGB03516.1 - 3.8 7.1 23.9 14 5.2 21.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EGB03516.1 - 4.2 5.5 14.4 5.9 5.1 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 EGB03517.1 - 6.5e-44 150.3 0.0 7.7e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03517.1 - 1.9e-19 70.0 0.0 2.3e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB03517.1 - 0.00019 20.9 0.0 0.00096 18.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like TPR_14 PF13428.6 EGB03517.1 - 0.00055 20.5 0.9 0.0015 19.2 0.9 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat LRR_8 PF13855.6 EGB03520.1 - 9.5e-13 47.7 16.8 1.7e-05 24.5 2.2 3.8 2 2 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGB03520.1 - 4.3e-11 42.9 14.9 3.2e-06 27.4 2.3 4.1 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB03520.1 - 2.2e-07 30.4 16.0 0.095 12.8 0.3 5.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 EGB03520.1 - 0.00018 21.6 13.6 0.084 13.5 0.4 5.3 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 EGB03520.1 - 0.0041 16.7 2.2 0.0071 15.9 1.1 1.7 1 1 1 2 2 2 1 Leucine-rich repeat Ank_2 PF12796.7 EGB03521.1 - 4.1e-26 91.4 0.6 6.6e-13 49.1 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB03521.1 - 2.1e-25 88.8 13.5 3.8e-13 49.7 1.2 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB03521.1 - 1.1e-17 62.3 0.7 1.7e-05 24.8 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EGB03521.1 - 7e-15 54.7 3.8 6.4e-05 23.2 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB03521.1 - 2.3e-13 50.1 6.5 4.7e-06 26.8 0.3 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EGB03521.1 - 0.13 12.0 0.0 0.21 11.3 0.1 1.3 2 0 0 2 2 2 0 Shigella flexneri OspC protein Histone PF00125.24 EGB03522.1 - 2.8e-32 111.8 0.1 3.8e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGB03522.1 - 0.00085 19.9 3.0 0.0011 19.5 3.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain LRR_8 PF13855.6 EGB03524.1 - 8e-29 99.2 23.3 3.8e-08 33.0 0.0 6.3 4 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EGB03524.1 - 1.4e-22 79.4 25.8 6.4e-05 23.2 2.1 7.4 4 3 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB03524.1 - 1.1e-09 37.6 24.9 0.2 11.8 0.3 9.6 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 EGB03524.1 - 5.8e-09 35.3 18.3 0.17 12.5 0.5 9.2 9 1 1 10 10 10 3 Leucine Rich Repeat LRR_9 PF14580.6 EGB03524.1 - 0.0099 15.4 8.8 2.3 7.7 0.1 3.9 1 1 2 4 4 4 3 Leucine-rich repeat O-FucT PF10250.9 EGB03526.1 - 7e-10 39.1 0.2 8.7e-07 28.9 0.1 2.1 1 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase XG_FTase PF03254.13 EGB03526.1 - 0.25 9.9 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Baculo_LEF5_C PF11792.8 EGB03527.1 - 0.039 13.6 1.7 9.3 6.0 0.1 2.7 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain O-FucT PF10250.9 EGB03528.1 - 2.3e-06 27.6 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase GvpL_GvpF PF06386.11 EGB03528.1 - 0.052 13.5 0.2 0.052 13.5 0.2 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Ephrin_rec_like PF07699.13 EGB03529.1 - 9.1e-15 54.2 32.1 6.6e-05 22.6 6.3 4.6 2 2 2 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 EGB03529.1 - 6.6e-08 32.4 25.9 0.024 14.6 0.9 4.3 4 0 0 4 4 4 4 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EGB03529.1 - 0.0017 18.7 25.0 0.18 12.2 0.1 6.0 2 2 4 6 6 6 3 TNFR/NGFR cysteine-rich region VSP PF03302.13 EGB03529.1 - 0.015 14.2 18.7 0.12 11.2 4.1 2.1 1 1 0 2 2 2 0 Giardia variant-specific surface protein VCBS PF13517.6 EGB03530.1 - 9.1e-45 151.1 89.9 1.4e-10 41.6 7.7 6.0 1 1 5 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3197 PF11432.8 EGB03530.1 - 6e-06 26.1 0.4 3.9 7.4 0.0 5.2 2 2 4 6 6 6 1 Protein of unknown function (DUF3197) DUF1510 PF07423.11 EGB03530.1 - 0.0028 17.7 2.2 16 5.7 0.0 5.1 6 0 0 6 6 6 0 Domain of unknown function (DUF1510) PLD_C PF12357.8 EGB03530.1 - 0.0034 17.3 0.0 21 5.1 0.0 4.0 4 0 0 4 4 4 0 Phospholipase D C terminal AbfS_sensor PF18225.1 EGB03530.1 - 0.0035 17.2 0.0 20 5.2 0.0 4.5 5 0 0 5 5 5 0 Sensor histidine kinase (AbfS) sensor domain Dockerin_1 PF00404.18 EGB03530.1 - 0.028 14.6 35.1 1.4 9.2 0.1 6.9 7 0 0 7 7 7 0 Dockerin type I domain HTH_31 PF13560.6 EGB03530.1 - 0.092 13.1 0.0 20 5.6 0.0 3.8 5 0 0 5 5 5 0 Helix-turn-helix domain DUF5541 PF17695.1 EGB03530.1 - 0.13 12.7 0.0 1e+02 3.4 0.0 4.2 4 1 1 5 5 5 0 Family of unknown function (DUF5541) DUF4265 PF14085.6 EGB03530.1 - 0.2 11.7 4.2 2.7 8.0 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4265) Phage_r1t_holin PF16945.5 EGB03530.1 - 1.4 9.2 11.7 1.3 9.3 0.3 4.2 5 0 0 5 5 5 0 Putative lactococcus lactis phage r1t holin BBS2_Mid PF14783.6 EGB03530.1 - 2.3 8.3 7.8 29 4.8 0.4 4.9 3 3 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region vWF_A PF12450.8 EGB03530.1 - 2.6 8.0 4.8 29 4.7 0.1 4.0 5 0 0 5 5 5 0 von Willebrand factor ABC_tran PF00005.27 EGB03531.1 - 3.4e-24 85.9 0.0 7.1e-10 39.5 0.0 3.3 3 0 0 3 3 3 3 ABC transporter AAA_21 PF13304.6 EGB03531.1 - 1.9e-08 34.5 2.8 0.02 14.7 0.1 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB03531.1 - 1.2e-07 31.4 0.3 0.048 13.1 0.0 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB03531.1 - 1.1e-05 25.1 0.8 0.0095 15.7 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGB03531.1 - 1.9e-05 24.8 0.1 0.64 10.3 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EGB03531.1 - 0.00016 21.5 0.5 4.1 7.1 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGB03531.1 - 0.00032 21.0 0.1 0.17 12.2 0.0 2.9 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB03531.1 - 0.00093 19.6 7.6 0.1 13.0 1.4 3.1 2 2 0 2 2 2 2 AAA ATPase domain TMEM154 PF15102.6 EGB03531.1 - 0.002 18.1 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family ATPase PF06745.13 EGB03531.1 - 0.012 15.0 0.1 5.7 6.2 0.0 2.6 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 EGB03531.1 - 0.021 14.7 0.1 7.8 6.4 0.0 3.2 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.18 EGB03531.1 - 0.024 14.0 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EGB03531.1 - 0.031 14.8 0.1 13 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGB03531.1 - 0.034 14.6 0.0 1.8 9.0 0.0 2.9 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB03531.1 - 0.082 13.3 0.0 21 5.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EGB03531.1 - 0.095 12.9 0.5 6.1 7.0 0.2 2.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGB03531.1 - 0.14 11.4 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 EGB03531.1 - 0.15 12.3 2.3 13 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 EGB03531.1 - 0.2 11.7 0.0 2.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain PT PF04886.12 EGB03531.1 - 9.3 5.9 27.7 0.029 13.9 7.8 2.9 3 0 0 3 3 3 0 PT repeat Nkap_C PF06047.11 EGB03532.1 - 2.8e-46 155.8 4.3 2.8e-46 155.8 4.3 2.1 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain SR-25 PF10500.9 EGB03532.1 - 1.8e-05 24.5 19.8 1.8e-05 24.5 19.8 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein YL1 PF05764.13 EGB03532.1 - 0.0002 21.6 12.5 0.00027 21.1 12.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 EGB03532.1 - 0.02 13.2 5.3 0.017 13.4 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Dsh_C PF12316.8 EGB03532.1 - 0.076 13.4 0.7 0.076 13.4 0.7 1.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal AP3D1 PF06375.11 EGB03532.1 - 0.44 10.8 17.2 0.99 9.6 17.2 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4502 PF14950.6 EGB03532.1 - 0.96 8.8 9.4 0.28 10.6 6.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4502) TFIIF_alpha PF05793.12 EGB03532.1 - 1.1 7.8 30.1 0.68 8.5 0.2 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_Rpc4 PF05132.14 EGB03532.1 - 1.7 9.0 7.3 3.1 8.2 7.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Glyoxalase_6 PF18029.1 EGB03533.1 - 1.1e-07 32.6 4.3 3.8e-05 24.4 0.6 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 EGB03533.1 - 0.0001 22.5 0.0 0.0043 17.2 0.0 2.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGB03533.1 - 0.054 13.6 0.4 0.46 10.6 0.0 2.3 1 1 1 3 3 3 0 Glyoxalase-like domain Thioredoxin PF00085.20 EGB03534.1 - 1.8e-16 60.0 0.1 2e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB03534.1 - 4.8e-08 33.4 0.1 1.1e-06 29.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGB03534.1 - 3e-06 26.8 0.0 3.2e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EGB03534.1 - 1.8e-05 24.7 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.6 EGB03534.1 - 5.2e-05 23.5 0.0 0.063 13.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EGB03534.1 - 0.00056 19.7 0.0 0.00057 19.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 EGB03534.1 - 0.012 15.5 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF836 PF05768.14 EGB03534.1 - 0.067 13.6 0.0 0.081 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.21 EGB03534.1 - 0.083 12.8 0.1 0.13 12.1 0.1 1.3 1 1 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 EGB03534.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin DIM1 PF02966.16 EGB03534.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.0 1 0 0 1 1 1 0 Mitosis protein DIM1 Evr1_Alr PF04777.13 EGB03535.1 - 2.8e-13 50.2 0.0 3.2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Peptidase_S26 PF10502.9 EGB03536.1 - 4.8e-07 29.7 0.0 6.2e-06 26.0 0.0 2.2 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EGB03536.1 - 1.9e-06 27.7 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DNA_methylase PF00145.17 EGB03537.1 - 8e-10 38.6 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase rve PF00665.26 EGB03537.1 - 0.084 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain ABC_tran PF00005.27 EGB03538.1 - 7.2e-25 88.1 0.0 9.4e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB03538.1 - 2e-05 24.6 0.4 5.7e-05 23.1 0.3 1.8 2 1 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EGB03538.1 - 0.00014 21.4 0.2 0.098 12.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB03538.1 - 0.00097 18.9 0.7 0.02 14.6 0.2 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGB03538.1 - 0.0011 19.3 0.1 0.0059 17.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB03538.1 - 0.0015 18.4 0.3 0.91 9.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGB03538.1 - 0.0016 18.0 1.4 0.1 12.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGB03538.1 - 0.0035 17.1 0.3 0.0086 15.8 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB03538.1 - 0.0048 17.0 0.3 0.009 16.1 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 EGB03538.1 - 0.015 15.7 0.3 1.6 9.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGB03538.1 - 0.015 15.6 0.2 0.031 14.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EGB03538.1 - 0.016 14.8 0.4 0.029 14.0 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGB03538.1 - 0.023 15.1 0.1 6.8 7.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGB03538.1 - 0.025 15.1 0.0 0.042 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EGB03538.1 - 0.033 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 EGB03538.1 - 0.045 13.7 0.1 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 EGB03538.1 - 0.098 11.9 0.0 0.23 10.7 0.1 1.5 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.9 EGB03538.1 - 0.1 11.4 0.2 0.15 10.9 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NACHT PF05729.12 EGB03538.1 - 0.11 12.4 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 EGB03538.1 - 0.14 12.3 0.3 0.21 11.6 0.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 EGB03538.1 - 0.14 12.4 0.3 0.35 11.1 0.3 1.6 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 EGB03538.1 - 0.16 11.7 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 MukB N-terminal ATPase_2 PF01637.18 EGB03538.1 - 0.24 11.3 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGB03539.1 - 4.6e-22 79.0 0.0 5.9e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB03539.1 - 3.5e-08 33.6 0.1 1.6e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB03539.1 - 0.082 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB03539.1 - 0.094 13.1 0.3 0.18 12.1 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EGB03539.1 - 0.13 11.7 0.0 14 5.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGB03539.1 - 0.25 11.8 0.1 0.34 11.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB03540.1 - 2.3e-24 86.4 0.0 3.5e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB03540.1 - 9.6e-09 35.5 0.0 2.8e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EGB03540.1 - 0.0036 17.6 0.1 3 8.1 0.0 3.0 2 1 1 3 3 3 1 AAA domain SMC_N PF02463.19 EGB03540.1 - 0.021 14.3 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB03540.1 - 0.046 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 EGB03540.1 - 0.074 12.4 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 EGB03540.1 - 0.093 13.1 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EGB03540.1 - 0.18 12.1 0.1 0.74 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGB03540.1 - 0.19 12.2 0.0 0.34 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain VWA PF00092.28 EGB03541.1 - 2.4e-05 24.7 0.0 0.074 13.3 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Trypan_PARP PF05887.11 EGB03541.1 - 0.0035 17.3 5.4 0.0076 16.2 5.4 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DEC-1_N PF04625.13 EGB03541.1 - 0.016 14.3 4.0 0.023 13.7 4.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PT PF04886.12 EGB03541.1 - 2.9 7.5 35.6 5.3 6.7 35.6 1.4 1 0 0 1 1 1 0 PT repeat TALPID3 PF15324.6 EGB03541.1 - 6.3 4.3 9.0 8.9 3.8 9.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target LRR_8 PF13855.6 EGB03542.1 - 4.2e-15 55.3 17.9 4e-05 23.3 2.0 4.0 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EGB03542.1 - 1.2e-11 44.7 15.4 9.6e-06 25.9 2.4 3.9 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB03542.1 - 2.4e-05 24.0 17.2 0.23 11.6 0.3 5.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 EGB03542.1 - 0.00019 21.5 12.3 0.37 11.5 0.6 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 EGB03542.1 - 0.01 15.3 4.2 0.063 12.8 0.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeat Peptidase_S49_N PF08496.10 EGB03543.1 - 0.093 12.8 2.0 0.14 12.2 2.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3535 PF12054.8 EGB03543.1 - 0.21 10.8 8.9 0.25 10.5 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) YjbH PF06082.11 EGB03543.1 - 0.59 8.9 5.9 0.7 8.6 5.9 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH PepSY_TM PF03929.16 EGB03543.1 - 0.69 9.5 2.8 0.96 9.1 2.8 1.3 1 0 0 1 1 1 0 PepSY-associated TM region SDH_beta PF03315.15 EGB03543.1 - 1.2 9.5 4.0 2 8.7 4.0 1.4 1 0 0 1 1 1 0 Serine dehydratase beta chain Band_3_cyto PF07565.13 EGB03543.1 - 1.4 8.6 7.5 2.1 8.1 7.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ABC_membrane PF00664.23 EGB03544.1 - 9.1e-33 114.1 3.2 1.3e-32 113.5 3.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB03544.1 - 2.3e-29 102.7 0.0 5.4e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGB03544.1 - 0.00012 21.6 0.5 0.0097 15.4 0.3 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB03544.1 - 0.0064 16.2 0.4 0.055 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGB03544.1 - 0.08 13.2 3.7 0.16 12.2 0.5 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EGB03544.1 - 0.087 12.7 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGB03544.1 - 0.1 13.0 0.1 0.1 13.0 0.1 2.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 EGB03544.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGB03544.1 - 0.12 11.9 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGB03544.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 EGB03545.1 - 1.9e-27 96.5 0.0 2.5e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB03545.1 - 7.3e-05 22.7 2.5 0.00022 21.2 1.1 2.2 2 1 1 3 3 3 1 RsgA GTPase AAA_21 PF13304.6 EGB03545.1 - 8.5e-05 22.5 2.5 0.045 13.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB03545.1 - 8.9e-05 22.0 1.8 0.0027 17.2 1.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB03545.1 - 0.0015 18.2 2.7 0.0063 16.2 2.1 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB03545.1 - 0.0026 17.8 0.4 0.0051 16.9 0.4 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EGB03545.1 - 0.0056 16.4 0.1 0.0087 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB03545.1 - 0.0059 17.0 0.1 0.0083 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGB03545.1 - 0.0069 16.9 0.8 0.02 15.4 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB03545.1 - 0.0081 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB03545.1 - 0.028 14.7 0.2 0.046 14.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB03545.1 - 0.076 13.4 0.1 0.18 12.2 0.1 1.6 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 EGB03545.1 - 0.13 11.9 1.2 0.19 11.4 1.2 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 EGB03545.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EGB03545.1 - 0.18 11.5 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 EGB03545.1 - 0.18 11.9 2.5 0.32 11.0 2.5 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Pkinase PF00069.25 EGB03546.1 - 1.2e-46 159.3 0.0 1.4e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03546.1 - 7.3e-22 77.9 0.0 9.8e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB03547.1 - 2.5e-10 40.2 0.0 3.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03547.1 - 3.2e-07 29.9 0.0 4.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Cdc6_C PF09079.11 EGB03547.1 - 0.064 13.2 0.2 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain HrpB7 PF09486.10 EGB03547.1 - 0.36 11.2 5.4 1.5 9.2 0.5 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF543 PF04418.12 EGB03549.1 - 0.41 10.7 3.8 1.1 9.2 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF543) DUF1883 PF08980.10 EGB03549.1 - 0.61 10.1 2.0 4.6 7.2 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1883) Ephrin_rec_like PF07699.13 EGB03550.1 - 2.2 8.1 10.3 2.5 7.9 0.2 2.6 2 0 0 2 2 2 0 Putative ephrin-receptor like SNF2_N PF00176.23 EGB03551.1 - 1.3e-16 60.3 0.0 2.4e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGB03551.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB03551.1 - 0.00023 21.0 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EGB03551.1 - 0.054 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_34 PF13872.6 EGB03551.1 - 0.078 11.9 0.0 2.3 7.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 NAD_kinase PF01513.21 EGB03551.1 - 0.097 11.9 0.3 0.15 11.2 0.3 1.3 1 0 0 1 1 1 0 ATP-NAD kinase AAA_22 PF13401.6 EGB03551.1 - 0.19 12.0 0.1 0.91 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Paramecium_SA PF01508.16 EGB03553.1 - 0.0059 17.0 22.5 0.0059 17.0 22.5 3.0 1 1 2 3 3 3 2 Paramecium surface antigen domain SelR PF01641.18 EGB03554.1 - 1.8e-29 102.3 0.3 2.4e-29 101.9 0.3 1.1 1 0 0 1 1 1 1 SelR domain Zn_Tnp_IS1 PF03811.13 EGB03554.1 - 3 7.6 12.4 8.7 6.2 5.6 2.6 2 0 0 2 2 2 0 InsA N-terminal domain ABC1 PF03109.16 EGB03555.1 - 6.5e-28 97.3 0.0 1.4e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB03555.1 - 0.0026 17.7 2.3 0.022 14.7 0.7 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGB03555.1 - 0.21 10.9 0.0 0.43 9.9 0.0 1.4 2 0 0 2 2 2 0 Protein kinase domain PDZ_6 PF17820.1 EGB03556.1 - 1.1e-13 50.8 6.5 9.3e-08 31.8 0.8 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EGB03556.1 - 1.3e-06 28.7 0.0 4e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 PDZ domain ArfGap PF01412.18 EGB03556.1 - 4.3e-06 26.8 0.0 8.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PDZ PF00595.24 EGB03556.1 - 0.041 14.2 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Band_7 PF01145.25 EGB03557.1 - 2.9e-26 92.6 3.4 3.9e-26 92.2 3.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family TAFII28 PF04719.14 EGB03558.1 - 2.7e-18 65.9 0.0 4.2e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 EGB03558.1 - 0.044 14.1 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DHQ_synthase PF01761.20 EGB03560.1 - 2.3e-92 308.9 0.8 2.5e-90 302.2 0.8 2.1 1 1 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EGB03560.1 - 5.9e-07 29.4 1.8 3.5e-05 23.6 1.8 2.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cupin_8 PF13621.6 EGB03561.1 - 1.6e-17 64.0 0.1 4.5e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 EGB03561.1 - 0.0078 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein LRR_6 PF13516.6 EGB03562.1 - 3.5e-21 73.4 14.3 0.00038 20.3 0.1 6.4 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 EGB03562.1 - 4.5e-08 32.6 0.7 2 9.2 0.1 5.2 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_8 PF13855.6 EGB03562.1 - 4.1e-06 26.5 4.7 1.4 8.7 0.1 5.0 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EGB03562.1 - 0.00031 21.1 3.8 0.96 10.0 0.0 4.6 2 2 4 6 6 6 3 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 EGB03563.1 - 1.9e-11 44.3 3.6 4.3e-08 33.5 0.5 1.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB03563.1 - 4.5e-10 38.3 0.5 2.3e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB03563.1 - 6.6e-10 38.1 0.1 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB03563.1 - 5.3e-08 32.6 1.2 0.00058 19.7 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB03563.1 - 1.2e-07 30.9 2.1 0.0035 16.8 0.5 2.3 2 0 0 2 2 2 2 EF hand Snf7 PF03357.21 EGB03563.1 - 0.029 13.9 0.1 0.032 13.8 0.1 1.2 1 0 0 1 1 1 0 Snf7 LRR_6 PF13516.6 EGB03564.1 - 3.1e-11 42.4 2.7 0.13 12.3 0.0 8.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 EGB03564.1 - 1.9e-05 24.9 0.0 0.22 12.0 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB03564.1 - 0.009 16.4 7.1 2.1e+02 3.2 0.0 7.2 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 EGB03564.1 - 0.022 14.5 0.0 2.7 7.8 0.0 3.5 3 1 0 3 3 3 0 Leucine rich repeat Ion_trans PF00520.31 EGB03566.1 - 5.5e-10 38.9 0.1 1.1e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Ion transport protein Thg1 PF04446.12 EGB03567.1 - 3.1e-14 53.1 0.0 4.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Ion_trans PF00520.31 EGB03569.1 - 4.2e-13 49.1 7.5 5.4e-13 48.8 7.5 1.2 1 0 0 1 1 1 1 Ion transport protein DUF2207 PF09972.9 EGB03569.1 - 0.036 12.8 1.4 0.042 12.6 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TssO PF17561.2 EGB03569.1 - 0.059 13.5 0.2 0.059 13.5 0.2 2.6 3 0 0 3 3 3 0 Type VI secretion system, TssO PRA-PH PF01503.17 EGB03569.1 - 0.7 10.4 2.1 15 6.1 0.1 2.3 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase PseudoU_synth_2 PF00849.22 EGB03570.1 - 1.8e-26 93.1 0.0 2.3e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase PSCyt1 PF07635.11 EGB03570.1 - 0.21 12.2 0.2 1.6 9.4 0.1 2.5 2 1 0 2 2 2 0 Planctomycete cytochrome C cEGF PF12662.7 EGB03571.1 - 0.18 11.8 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Complement Clr-like EGF-like DcpS_C PF11969.8 EGB03573.1 - 8.6e-10 39.1 0.0 2.9e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding TolA_bind_tri PF16331.5 EGB03573.1 - 5.1 7.2 13.5 1.6 8.9 3.3 4.4 3 2 1 4 4 4 0 TolA binding protein trimerisation PT PF04886.12 EGB03575.1 - 1.4e-07 31.0 51.2 1.3e-05 24.6 18.5 2.8 1 1 1 2 2 2 2 PT repeat Orn_Arg_deC_N PF02784.16 EGB03577.1 - 5.3e-34 117.7 0.0 6.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGB03577.1 - 2.3e-17 63.0 0.0 3.1e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain WD40 PF00400.32 EGB03579.1 - 1.1e-34 117.8 3.4 6.4e-11 42.6 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB03579.1 - 3.6e-19 68.8 0.0 6.6e-06 26.3 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB03579.1 - 0.00096 19.1 0.0 0.002 18.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGB03579.1 - 0.004 15.8 0.0 0.0051 15.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome D1 heme domain DUF1513 PF07433.11 EGB03579.1 - 0.0041 16.2 0.1 1.3 8.0 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) Nup160 PF11715.8 EGB03579.1 - 0.012 14.3 0.1 2.4 6.7 0.0 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 EGB03579.1 - 0.014 15.3 0.2 0.029 14.3 0.2 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGB03579.1 - 0.031 13.3 0.0 0.55 9.1 0.0 2.6 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein E1-E2_ATPase PF00122.20 EGB03580.1 - 1.5e-40 138.6 0.2 1.5e-40 138.6 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGB03580.1 - 7.2e-38 131.0 9.4 4.3e-37 128.5 5.2 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGB03580.1 - 5.1e-20 71.7 0.0 2e-14 53.8 0.1 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGB03580.1 - 4.4e-06 26.6 0.2 3e-05 23.9 0.5 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB03580.1 - 0.00068 20.1 6.0 0.013 15.9 0.5 3.8 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase DcpS_C PF11969.8 EGB03581.1 - 1e-15 58.2 0.0 1.2e-15 57.9 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGB03581.1 - 1.1e-09 38.9 0.1 2.3e-09 37.9 0.1 1.5 1 1 0 1 1 1 1 HIT domain tRNA-synt_1b PF00579.25 EGB03582.1 - 1.5e-69 234.6 0.0 1.7e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EGB03582.1 - 1.8e-06 27.5 1.9 1.8e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 S4 domain TyrRSs_C PF16714.5 EGB03582.1 - 0.00085 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain TPR_16 PF13432.6 EGB03583.1 - 1.2e-07 32.2 8.0 6.8e-06 26.6 4.8 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGB03583.1 - 1.4e-05 25.1 3.5 7.2 7.2 0.2 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB03583.1 - 0.0057 16.4 0.5 0.0057 16.4 0.5 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB03583.1 - 0.016 15.3 15.7 0.098 12.8 2.3 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB03583.1 - 0.02 14.5 0.2 6.3 6.6 0.0 3.4 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 EGB03583.1 - 0.38 10.9 6.3 4.4 7.6 1.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB03583.1 - 1.5 9.4 12.0 0.16 12.5 2.6 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB03583.1 - 3.7 7.9 19.6 0.066 13.5 6.9 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat S1 PF00575.23 EGB03584.1 - 2e-32 111.4 2.0 1.9e-17 63.4 0.2 2.3 2 0 0 2 2 2 2 S1 RNA binding domain TRAM_2 PF18693.1 EGB03584.1 - 0.0036 17.4 2.0 0.026 14.7 0.2 2.5 2 0 0 2 2 2 1 TRAM domain RNase_II_C_S1 PF18614.1 EGB03584.1 - 0.036 14.0 6.2 0.13 12.2 0.1 3.5 3 1 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain Kinesin PF00225.23 EGB03585.1 - 1.7e-49 168.5 0.0 2.1e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB03585.1 - 3.2e-10 40.1 0.0 5.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DEAD PF00270.29 EGB03585.1 - 0.0056 16.5 0.1 0.055 13.2 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGB03585.1 - 0.0085 16.4 0.1 0.013 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB03585.1 - 0.0097 16.3 0.1 0.015 15.7 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AraC_N PF06719.13 EGB03585.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 AraC-type transcriptional regulator N-terminus TniB PF05621.11 EGB03585.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Kinesin PF00225.23 EGB03586.1 - 5.7e-76 255.6 0.0 7.9e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB03586.1 - 7.2e-11 42.2 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 EGB03586.1 - 0.0074 16.6 0.8 0.053 13.8 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB03586.1 - 0.017 15.5 0.7 0.061 13.7 0.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 EGB03586.1 - 0.035 13.9 0.1 0.2 11.4 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase PhyH PF05721.13 EGB03587.1 - 2.5e-16 60.6 0.2 7.7e-16 59.0 0.2 1.8 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ctr PF04145.15 EGB03587.1 - 0.0035 18.0 0.7 11 6.7 0.0 3.4 3 0 0 3 3 3 2 Ctr copper transporter family DUF3989 PF13150.6 EGB03587.1 - 0.021 14.6 0.3 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) FliX PF10768.9 EGB03587.1 - 0.032 14.8 0.1 0.032 14.8 0.1 2.5 2 0 0 2 2 2 0 Class II flagellar assembly regulator TctB PF07331.11 EGB03587.1 - 0.13 12.5 14.3 4.9 7.4 0.1 3.8 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family STE3 PF02076.15 EGB03587.1 - 0.16 11.1 3.9 2.6 7.2 0.3 2.3 2 0 0 2 2 2 0 Pheromone A receptor PDE4_UCR PF18100.1 EGB03587.1 - 0.78 10.4 2.0 39 4.9 0.1 2.3 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) TBP PF00352.21 EGB03588.1 - 1.6e-61 204.2 0.2 9.6e-32 108.8 0.3 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) SBD PF17882.1 EGB03588.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 OAA-family lectin sugar binding domain Solute_trans_a PF03619.16 EGB03589.1 - 2.8e-58 197.5 0.0 3.5e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4389 PF14333.6 EGB03589.1 - 0.24 11.3 2.3 0.44 10.5 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) CAP_N PF01213.19 EGB03589.1 - 8.4 5.8 8.5 9.3 5.6 7.8 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ion_trans PF00520.31 EGB03590.1 - 6.1e-14 51.9 7.1 9.6e-14 51.2 7.1 1.2 1 0 0 1 1 1 1 Ion transport protein FKBP_C PF00254.28 EGB03593.1 - 7.9e-27 93.4 0.0 8.5e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pet100 PF09803.9 EGB03595.1 - 0.11 13.0 0.1 0.25 11.9 0.1 1.6 1 0 0 1 1 1 0 Pet100 Cytochrome_CBB3 PF13442.6 EGB03596.1 - 5e-17 62.0 0.0 6.4e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EGB03596.1 - 8.1e-09 36.5 0.5 3e-08 34.7 0.5 1.8 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 EGB03596.1 - 2.1e-06 27.5 0.2 0.0011 18.7 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c-550 domain YIF1 PF03878.15 EGB03597.1 - 1.8e-44 152.1 0.0 2.1e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EGB03597.1 - 0.0004 20.1 8.6 0.0004 20.1 8.6 2.6 1 1 1 2 2 2 2 Yip1 domain Vps26 PF03643.15 EGB03598.1 - 5.4e-94 314.2 1.4 6.7e-94 313.9 1.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Sel1 PF08238.12 EGB03599.1 - 1.6e-30 104.9 24.5 3.1e-07 30.8 0.5 7.4 7 1 0 7 7 7 6 Sel1 repeat EF-hand_like PF09279.11 EGB03599.1 - 0.00019 21.8 0.2 0.13 12.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like CZB PF13682.6 EGB03599.1 - 0.026 15.0 0.1 2.4 8.7 0.0 3.1 2 1 0 2 2 2 0 Chemoreceptor zinc-binding domain AAA_lid_10 PF17872.1 EGB03599.1 - 0.032 14.3 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA lid domain DUF3228 PF11539.8 EGB03599.1 - 0.079 12.5 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) DUF977 PF06163.11 EGB03599.1 - 0.12 12.3 1.0 7 6.6 0.0 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF977) B12-binding_2 PF02607.17 EGB03599.1 - 2.6 8.5 10.2 19 5.8 1.4 3.6 2 2 1 3 3 3 0 B12 binding domain Rhomboid PF01694.22 EGB03600.1 - 4.1e-25 88.5 9.9 4.6e-25 88.4 9.9 1.0 1 0 0 1 1 1 1 Rhomboid family PI3_PI4_kinase PF00454.27 EGB03601.1 - 2.8e-33 115.8 0.0 6.3e-32 111.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EGB03601.1 - 0.0025 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) NADH5_C PF06455.11 EGB03601.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus FAD_binding_3 PF01494.19 EGB03602.1 - 4.2e-25 88.7 0.0 6.1e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGB03602.1 - 2.8e-05 23.9 1.7 0.098 12.2 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGB03602.1 - 0.00011 22.4 0.3 0.00035 20.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGB03602.1 - 0.0015 19.0 0.1 0.019 15.5 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB03602.1 - 0.0049 16.2 0.0 0.033 13.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGB03602.1 - 0.0066 16.1 0.2 0.013 15.2 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EGB03602.1 - 0.0093 15.9 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGB03602.1 - 0.07 13.1 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SE PF08491.10 EGB03602.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Epimerase PF01370.21 EGB03602.1 - 0.13 11.7 0.1 1.4 8.3 0.1 2.2 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Transglut_core PF01841.19 EGB03603.1 - 8.1e-05 23.0 0.0 0.00038 20.9 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily DUF3768 PF12599.8 EGB03603.1 - 0.089 12.8 0.0 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3768) Peptidase_M28 PF04389.17 EGB03604.1 - 4e-09 36.4 0.0 4e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGB03604.1 - 0.067 12.9 0.0 0.072 12.8 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MCM PF00493.23 EGB03605.1 - 1.2e-97 325.4 0.0 7e-97 322.9 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGB03605.1 - 5.3e-37 126.5 0.0 9.2e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGB03605.1 - 2.7e-24 85.4 0.8 1.1e-23 83.4 0.3 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGB03605.1 - 3.7e-14 53.2 0.0 1.1e-13 51.7 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGB03605.1 - 2.8e-07 30.1 0.1 0.00017 21.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB03605.1 - 2e-06 27.8 0.0 6.4e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB03605.1 - 0.0019 18.0 0.0 0.0053 16.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CBFD_NFYB_HMF PF00808.23 EGB03606.1 - 3.6e-14 52.8 1.2 4.5e-14 52.5 0.5 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB03606.1 - 3.2e-06 27.5 0.1 4.1e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 LMBR1 PF04791.16 EGB03607.1 - 1.9e-21 76.6 17.9 8.2e-14 51.4 14.5 2.5 1 1 1 2 2 2 2 LMBR1-like membrane protein LSM PF01423.22 EGB03608.1 - 2e-16 59.4 0.0 2.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGB03608.1 - 5e-06 26.6 0.0 7.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain FtsJ PF01728.19 EGB03609.1 - 5.7e-49 166.6 0.0 7.2e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase E1-N PF14463.6 EGB03609.1 - 0.0052 16.6 1.9 0.0052 16.6 1.9 2.2 2 0 0 2 2 2 1 E1 N-terminal domain Methyltr_RsmB-F PF01189.17 EGB03609.1 - 0.063 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F tRNA-synt_2b PF00587.25 EGB03610.1 - 8.1e-42 143.2 0.0 1.4e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGB03610.1 - 3.6e-15 55.9 0.0 8.8e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGB03610.1 - 5.1e-14 52.1 0.0 1.6e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain FIST_C PF10442.9 EGB03611.1 - 4.1e-18 65.6 0.1 8.9e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 FIST C domain FIST PF08495.10 EGB03611.1 - 5.9e-05 23.1 0.4 0.041 13.9 0.1 2.6 2 1 0 2 2 2 2 FIST N domain F-box PF00646.33 EGB03612.1 - 9.9e-05 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGB03612.1 - 0.00061 19.6 0.6 0.0015 18.4 0.6 1.6 1 0 0 1 1 1 1 F-box-like Nucleoporin2 PF04096.14 EGB03613.1 - 6.2e-25 88.0 0.0 1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase PLAC8 PF04749.17 EGB03613.1 - 2.3e-09 38.1 8.3 4e-09 37.4 8.3 1.3 1 0 0 1 1 1 1 PLAC8 family DUF5335 PF17269.2 EGB03613.1 - 0.23 11.3 0.1 0.9 9.4 0.0 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5335) Mg-por_mtran_C PF07109.11 EGB03614.1 - 1.5e-33 115.0 0.0 2.7e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 EGB03614.1 - 1.8e-13 51.0 0.2 3.7e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03614.1 - 1.2e-10 41.4 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB03614.1 - 6.2e-10 39.1 0.0 7.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03614.1 - 1e-07 32.6 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB03614.1 - 1e-06 28.4 0.3 1.6e-06 27.7 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGB03614.1 - 1.3e-06 29.0 0.1 2.7e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB03614.1 - 1.8e-06 27.5 0.0 3e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGB03614.1 - 3.7e-06 26.4 0.1 5.1e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGB03614.1 - 2.7e-05 23.7 1.0 3e-05 23.6 0.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGB03614.1 - 0.00018 21.5 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EGB03614.1 - 0.0014 17.7 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 EGB03614.1 - 0.0014 18.5 0.2 0.0086 16.0 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 EGB03614.1 - 0.0058 15.8 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase TehB PF03848.14 EGB03614.1 - 0.0095 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 EGB03614.1 - 0.015 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_15 PF09445.10 EGB03614.1 - 0.042 13.4 0.0 0.081 12.5 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 EGB03614.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.16 EGB03614.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Pkinase PF00069.25 EGB03615.1 - 3.2e-25 89.0 0.0 3.6e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03615.1 - 1.3e-11 44.3 0.0 1.5e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase CDO_I PF05995.12 EGB03616.1 - 2.5e-30 105.0 0.0 2.8e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EGB03616.1 - 0.035 13.6 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 PCO_ADO DUF4272 PF14094.6 EGB03616.1 - 0.058 12.6 0.2 0.077 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) ER_lumen_recept PF00810.18 EGB03617.1 - 5.1e-33 115.0 0.7 6.9e-33 114.5 0.0 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor AAA PF00004.29 EGB03618.1 - 2.1e-14 54.1 0.0 4.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB03618.1 - 0.00038 20.9 2.1 0.011 16.2 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGB03618.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 EGB03618.1 - 0.0029 16.8 0.1 0.085 12.0 0.1 2.5 2 0 0 2 2 2 1 NB-ARC domain IQ PF00612.27 EGB03618.1 - 0.0041 16.8 0.3 0.013 15.2 0.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_22 PF13401.6 EGB03618.1 - 0.0045 17.3 0.3 0.023 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGB03618.1 - 0.0065 16.2 2.2 0.14 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB03618.1 - 0.011 15.9 0.0 0.011 15.9 0.0 2.3 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 EGB03618.1 - 0.027 13.8 1.6 0.04 13.3 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGB03618.1 - 0.033 14.2 0.1 0.077 13.0 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EGB03618.1 - 0.043 13.0 0.1 0.043 13.0 0.1 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain NACHT PF05729.12 EGB03618.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGB03618.1 - 0.06 13.7 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EGB03618.1 - 0.061 13.3 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGB03618.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 EGB03618.1 - 0.12 11.4 1.1 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 EGB03618.1 - 0.13 12.8 0.0 0.13 12.8 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 EGB03618.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mito_carr PF00153.27 EGB03619.1 - 1.1e-20 73.4 5.6 6e-08 32.5 0.0 5.1 2 2 1 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_3 PF00933.21 EGB03620.1 - 2e-34 119.4 0.0 3e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EGB03620.1 - 5.3e-22 78.8 0.1 7.1e-16 58.8 0.0 3.2 2 1 1 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EGB03620.1 - 3.1e-09 36.8 0.0 6.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain IQ PF00612.27 EGB03621.1 - 7e-05 22.3 5.4 0.0091 15.7 0.8 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif 2OG-FeII_Oxy_5 PF13759.6 EGB03622.1 - 1.7e-11 44.4 0.0 7.1e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase PT PF04886.12 EGB03622.1 - 0.00026 20.5 18.3 0.00026 20.5 18.3 12.6 5 4 3 8 8 8 4 PT repeat HSP90 PF00183.18 EGB03623.1 - 8.8e-143 476.9 0.0 7e-133 444.3 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 EGB03623.1 - 2.5e-11 44.1 0.0 5.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGB03623.1 - 4.4e-10 39.5 0.3 9.8e-10 38.4 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.27 EGB03624.1 - 6.9e-44 147.7 2.7 8.4e-15 54.5 0.1 3.0 1 1 2 3 3 3 3 Mitochondrial carrier protein Aminotran_5 PF00266.19 EGB03625.1 - 2.8e-08 33.1 0.0 4.9e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGB03625.1 - 0.32 10.2 0.9 0.66 9.2 0.9 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Branch PF02485.21 EGB03626.1 - 0.024 14.2 0.0 3.7 7.0 0.0 2.0 2 0 0 2 2 2 0 Core-2/I-Branching enzyme Xan_ur_permease PF00860.20 EGB03628.1 - 7e-60 202.8 19.3 6.9e-58 196.2 19.3 2.1 1 1 0 1 1 1 1 Permease family Ion_trans_2 PF07885.16 EGB03629.1 - 1.5e-10 40.9 8.0 1.7e-10 40.7 8.0 1.0 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB03629.1 - 0.00067 19.0 1.5 0.00067 19.0 1.5 1.0 1 0 0 1 1 1 1 Ion transport protein IRK PF01007.20 EGB03629.1 - 0.006 16.4 0.2 0.008 16.0 0.2 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain ANAPC4_WD40 PF12894.7 EGB03630.1 - 0.12 12.7 0.0 9.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_12 PF13424.6 EGB03631.1 - 1.1e-65 217.9 36.4 1.2e-17 63.9 0.3 6.3 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 EGB03631.1 - 1.2e-51 171.3 26.6 1.5e-09 37.4 0.4 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGB03631.1 - 6.5e-19 66.5 18.0 5.7e-05 22.9 0.2 6.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB03631.1 - 1.5e-15 55.9 12.7 0.0004 20.3 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB03631.1 - 4e-14 51.6 7.9 0.0077 16.4 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGB03631.1 - 4.9e-14 51.4 8.6 4.3e-05 23.2 0.1 6.1 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB03631.1 - 1.5e-07 31.1 1.5 2.2e-05 24.0 0.1 2.0 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EGB03631.1 - 1.7e-05 25.3 22.6 0.48 11.4 0.2 6.5 4 2 3 7 7 6 2 Tetratricopeptide repeat Mob_Pre PF01076.19 EGB03631.1 - 2.2e-05 24.4 0.0 1.3 8.8 0.0 4.9 5 1 1 6 6 6 1 Plasmid recombination enzyme TPR_6 PF13174.6 EGB03631.1 - 5.1e-05 23.6 9.8 0.74 10.6 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Tcf25 PF04910.14 EGB03631.1 - 0.00016 20.9 0.4 1.7 7.6 0.0 4.2 2 2 3 5 5 5 2 Transcriptional repressor TCF25 Wzy_C_2 PF11846.8 EGB03631.1 - 0.00016 21.6 2.4 0.7 9.8 0.0 3.9 2 2 2 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal DUF2225 PF09986.9 EGB03631.1 - 0.00035 20.4 0.2 1.4 8.6 0.1 3.7 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 EGB03631.1 - 0.00099 19.5 12.4 0.12 13.1 0.0 6.0 7 1 1 8 8 6 2 Tetratricopeptide repeat DUF2989 PF11207.8 EGB03631.1 - 0.0041 16.9 0.2 1.4 8.6 0.0 3.1 1 1 1 3 3 3 1 Protein of unknown function (DUF2989) TPR_16 PF13432.6 EGB03631.1 - 0.0042 17.7 21.6 0.55 10.9 5.3 4.9 4 2 0 4 4 4 2 Tetratricopeptide repeat pKID PF02173.17 EGB03631.1 - 0.013 15.0 8.1 31 4.1 0.0 5.7 6 0 0 6 6 6 0 pKID domain TPR_11 PF13414.6 EGB03631.1 - 0.019 14.7 4.9 6.5 6.5 0.0 4.4 4 0 0 4 4 4 0 TPR repeat DUF4807 PF16065.5 EGB03631.1 - 0.079 12.6 0.1 20 4.8 0.0 4.0 3 1 1 5 5 5 0 Domain of unknown function (DUF4807) DUF4113 PF13438.6 EGB03631.1 - 0.17 12.0 0.3 64 3.7 0.0 4.1 5 0 0 5 5 4 0 Domain of unknown function (DUF4113) DUF1501 PF07394.12 EGB03631.1 - 0.3 10.1 3.0 20 4.1 0.2 3.8 2 1 3 5 5 5 0 Protein of unknown function (DUF1501) MCM PF00493.23 EGB03633.1 - 1.1e-83 279.8 0.6 3.3e-82 274.9 0.6 2.1 1 1 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGB03633.1 - 1.6e-22 79.7 0.4 3.5e-22 78.6 0.4 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGB03633.1 - 2.7e-11 43.3 0.2 3e-07 30.1 0.1 3.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB03633.1 - 3e-07 30.5 0.0 7.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB03633.1 - 0.0011 18.9 0.0 0.0036 17.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EGB03633.1 - 0.0046 16.8 0.7 0.012 15.5 0.7 1.6 1 0 0 1 1 1 1 AAA lid domain Sigma54_activat PF00158.26 EGB03633.1 - 0.029 14.1 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF469 PF04320.14 EGB03633.1 - 0.069 14.0 0.1 12 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein with unknown function (DUF469) AAA PF00004.29 EGB03635.1 - 7.4e-25 87.9 0.0 1.3e-12 48.3 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB03635.1 - 1e-13 50.8 0.6 7.9e-08 32.0 0.0 3.0 2 0 0 2 2 2 2 AAA+ lid domain NACHT PF05729.12 EGB03635.1 - 0.00014 21.8 3.1 0.11 12.4 0.7 3.9 2 2 2 4 4 4 1 NACHT domain IstB_IS21 PF01695.17 EGB03635.1 - 0.00028 20.7 0.4 0.066 12.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 EGB03635.1 - 0.0005 20.5 6.3 1.4 9.3 0.5 4.2 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 EGB03635.1 - 0.0063 16.3 0.1 0.065 13.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGB03635.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGB03635.1 - 0.16 12.2 0.1 13 6.0 0.0 3.1 2 1 1 3 3 3 0 AAA domain VHS PF00790.19 EGB03637.1 - 4.2e-25 88.2 0.0 4.6e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 VHS domain DUF3361 PF11841.8 EGB03637.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Glucokinase PF02685.16 EGB03638.1 - 1.3e-44 152.5 0.0 1.7e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Glucokinase Dynein_C PF18199.1 EGB03639.1 - 1.5e-62 211.6 0.0 2.3e-62 211.0 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_6 PF12774.7 EGB03639.1 - 7.7e-50 169.7 0.0 1.7e-49 168.6 0.0 1.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 EGB03639.1 - 2.8e-38 131.7 0.0 5.2e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 EGB03639.1 - 3.5e-38 131.0 0.0 6e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 EGB03639.1 - 3.8e-37 127.6 0.0 1e-36 126.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region DHC_N2 PF08393.13 EGB03639.1 - 4e-36 125.0 0.0 7.2e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGB03639.1 - 8.2e-25 87.2 0.0 8.1e-24 84.0 0.0 2.5 3 0 0 3 3 2 1 ATP-binding dynein motor region Dynein_AAA_lid PF17852.1 EGB03639.1 - 4.3e-20 72.1 0.3 1e-19 70.9 0.0 1.9 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB03639.1 - 2.3e-15 56.8 0.0 1.5e-13 50.9 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGB03639.1 - 7.1e-10 38.4 0.1 1.3e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EGB03639.1 - 5.1e-09 36.2 0.0 0.00089 19.3 0.0 4.4 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB03639.1 - 3.4e-05 24.1 0.2 0.00035 20.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 EGB03639.1 - 0.00046 20.6 0.2 0.0057 17.1 0.0 3.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_1 PF17857.1 EGB03639.1 - 0.0027 17.9 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 EGB03639.1 - 0.0065 15.9 0.8 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGB03639.1 - 0.085 13.0 0.1 0.4 10.8 0.1 2.2 1 0 0 1 1 1 0 AAA domain DHR10 PF18595.1 EGB03639.1 - 0.13 12.3 4.8 0.42 10.7 4.8 1.8 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain AAA_16 PF13191.6 EGB03639.1 - 0.31 11.4 0.0 0.31 11.4 0.0 4.7 5 0 0 5 5 3 0 AAA ATPase domain MscS_porin PF12795.7 EGB03639.1 - 0.84 9.1 8.9 5.9 6.4 4.6 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain JIP_LZII PF16471.5 EGB03639.1 - 4.8 7.4 6.3 0.55 10.4 0.7 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 EGB03639.1 - 7.2 5.4 8.6 3.9 6.3 3.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA PF00004.29 EGB03640.1 - 4e-64 215.0 0.0 8e-44 149.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB03640.1 - 5.2e-19 67.8 3.8 2.9e-11 43.0 0.4 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGB03640.1 - 8.4e-14 52.3 0.7 0.00014 22.2 0.0 4.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGB03640.1 - 5.9e-08 33.1 0.2 0.023 15.0 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGB03640.1 - 2e-07 31.1 0.2 0.0006 19.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGB03640.1 - 2.3e-07 30.7 0.0 0.00075 19.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGB03640.1 - 7.2e-07 29.5 0.1 0.0026 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGB03640.1 - 4.3e-06 26.3 0.7 0.047 13.1 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGB03640.1 - 1.8e-05 25.1 0.0 0.086 13.2 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EGB03640.1 - 3.7e-05 24.3 0.1 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EGB03640.1 - 4.7e-05 23.2 0.1 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 EGB03640.1 - 7.4e-05 22.7 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGB03640.1 - 0.0001 22.3 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB03640.1 - 0.00016 21.6 0.1 0.38 10.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Viral_helicase1 PF01443.18 EGB03640.1 - 0.00026 20.8 0.1 0.44 10.2 0.2 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 EGB03640.1 - 0.0003 21.0 0.0 0.004 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EGB03640.1 - 0.00035 20.9 0.1 0.24 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGB03640.1 - 0.0004 19.7 0.1 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain ATPase PF06745.13 EGB03640.1 - 0.00064 19.1 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 2 KaiC ABC_tran PF00005.27 EGB03640.1 - 0.00069 20.1 0.0 1.2 9.6 0.0 2.8 2 1 1 3 3 3 1 ABC transporter AAA_25 PF13481.6 EGB03640.1 - 0.00092 18.8 2.7 0.38 10.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EGB03640.1 - 0.0015 18.2 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 EGB03640.1 - 0.0018 18.1 0.0 1.8 8.3 0.0 2.4 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EGB03640.1 - 0.0018 17.6 0.2 0.26 10.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 EGB03640.1 - 0.0019 18.0 0.0 0.63 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGB03640.1 - 0.0038 17.2 0.0 0.56 10.1 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EGB03640.1 - 0.004 17.0 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EGB03640.1 - 0.0053 16.0 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 EGB03640.1 - 0.0054 16.7 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EGB03640.1 - 0.0098 15.4 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 EGB03640.1 - 0.018 15.4 0.3 4.3 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EGB03640.1 - 0.02 14.4 0.7 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Nucleolin_bd PF16725.5 EGB03640.1 - 0.027 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Nucleolin binding domain AAA_19 PF13245.6 EGB03640.1 - 0.1 12.9 0.4 24 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGB03640.1 - 0.11 11.6 0.0 0.73 8.9 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DAP3 PF10236.9 EGB03640.1 - 0.16 11.1 0.0 3.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 EGB03640.1 - 0.23 11.1 5.1 6.9 6.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain SUIM_assoc PF16619.5 EGB03641.1 - 0.56 10.3 2.4 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CPBP PF02517.16 EGB03643.1 - 1.4e-13 51.0 6.7 1.6e-13 50.8 4.8 2.1 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease Cpn60_TCP1 PF00118.24 EGB03644.1 - 1.4e-147 492.3 15.6 1.5e-147 492.2 15.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L10 PF00466.20 EGB03645.1 - 3e-21 75.4 0.1 7.7e-21 74.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGB03645.1 - 3.2e-20 71.9 0.1 1.1e-19 70.2 0.1 1.9 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EGB03645.1 - 5.2e-09 36.6 3.4 8.7e-09 35.9 3.4 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pkinase PF00069.25 EGB03647.1 - 4.8e-67 226.1 0.0 7.2e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03647.1 - 7.1e-33 114.0 0.0 1.2e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGB03647.1 - 5.7e-18 63.1 0.1 0.00022 20.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB03647.1 - 1.8e-17 63.5 2.3 1.6e-07 31.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB03647.1 - 1.3e-13 49.7 0.2 0.0055 16.5 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGB03647.1 - 3.3e-09 35.8 3.3 0.00047 19.5 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EGB03647.1 - 7.3e-09 35.4 1.9 0.076 12.9 0.0 4.1 2 1 2 4 4 4 3 EF-hand domain pair APH PF01636.23 EGB03647.1 - 0.0052 16.7 0.3 0.019 14.9 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB03647.1 - 0.0094 15.3 0.6 0.13 11.6 0.5 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGB03647.1 - 0.033 13.6 3.5 0.022 14.1 0.9 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 EGB03647.1 - 0.093 12.7 2.3 9.3 6.3 0.0 3.3 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand Methyltransf_28 PF02636.17 EGB03648.1 - 9.5e-07 28.7 0.0 3.5e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_1 PF00515.28 EGB03648.1 - 5.8e-06 25.9 1.3 0.00045 19.9 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB03648.1 - 7.5e-06 25.7 7.1 0.0047 16.9 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB03648.1 - 0.0001 22.2 5.1 0.011 15.9 0.3 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB03648.1 - 0.00014 21.5 0.6 0.00059 19.5 0.1 2.4 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 EGB03648.1 - 0.0022 18.3 1.6 0.046 14.0 0.2 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB03648.1 - 0.12 13.1 4.3 1.2 9.9 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB03648.1 - 0.23 11.6 0.9 12 6.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_methylase PF00145.17 EGB03650.1 - 1.1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase HAUS-augmin3 PF14932.6 EGB03651.1 - 6.3 6.3 7.8 0.51 9.9 1.9 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 EMP70 PF02990.16 EGB03652.1 - 6.4e-158 526.7 7.6 8.7e-158 526.2 7.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 RNA_pol_Rpb2_1 PF04563.15 EGB03653.1 - 1.1e-48 165.4 0.0 1.7e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_6 PF00562.28 EGB03653.1 - 1.9e-40 139.2 0.0 3.1e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_4 PF04566.13 EGB03653.1 - 2.3e-22 79.0 0.3 5.3e-22 77.9 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGB03653.1 - 3.3e-22 78.4 0.0 7.9e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGB03653.1 - 4.3e-21 75.4 0.2 9.8e-21 74.2 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 EGB03653.1 - 1.2e-08 35.3 0.9 4.1e-08 33.7 0.9 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DNA_pol_E_B PF04042.16 EGB03654.1 - 1.4e-24 86.6 0.0 2.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B V_ATPase_I PF01496.19 EGB03654.1 - 1.9e-09 36.1 0.0 2.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DHR10 PF18595.1 EGB03654.1 - 0.045 13.8 5.5 0.34 11.0 2.4 2.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Chloroa_b-bind PF00504.21 EGB03655.1 - 4.6e-30 105.3 0.3 5.8e-30 104.9 0.3 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Glycos_transf_2 PF00535.26 EGB03657.1 - 1.2e-30 106.6 0.3 8.2e-15 55.0 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB03657.1 - 2.3e-18 66.9 0.5 2.8e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGB03657.1 - 6.2e-09 35.7 0.0 0.00076 19.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 UCH PF00443.29 EGB03658.1 - 3.1e-46 158.0 0.0 3.9e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB03658.1 - 1.7e-14 54.1 0.0 6.8e-13 48.9 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGB03658.1 - 6.3e-10 39.2 6.1 6.3e-10 39.2 6.1 3.5 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Prok-RING_1 PF14446.6 EGB03658.1 - 0.078 12.9 11.5 0.42 10.6 2.1 3.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Peptidase_C98 PF15499.6 EGB03658.1 - 6.1 6.2 10.7 17 4.8 0.0 3.8 5 0 0 5 5 5 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TIP49 PF06068.13 EGB03659.1 - 8.2e-169 561.3 0.1 1e-168 561.1 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGB03659.1 - 5e-23 81.0 0.3 1.5e-22 79.5 0.3 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGB03659.1 - 3.1e-10 40.6 0.0 2.7e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGB03659.1 - 1.6e-09 37.7 0.3 2.2e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB03659.1 - 6e-07 29.8 0.0 0.038 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGB03659.1 - 7.8e-05 23.1 0.1 0.00059 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGB03659.1 - 0.0008 19.4 0.1 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGB03659.1 - 0.0014 18.9 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGB03659.1 - 0.0019 17.7 0.3 0.055 12.9 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGB03659.1 - 0.0046 17.3 1.3 0.089 13.1 1.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB03659.1 - 0.0052 16.4 0.1 0.0095 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGB03659.1 - 0.0061 16.3 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain DnaB_C PF03796.15 EGB03659.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 EGB03659.1 - 0.017 14.4 0.2 0.034 13.4 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EGB03659.1 - 0.027 15.0 0.0 0.078 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB03659.1 - 0.036 14.2 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 EGB03659.1 - 0.039 12.6 0.1 0.36 9.4 0.0 2.1 2 0 0 2 2 2 0 GvpD gas vesicle protein IstB_IS21 PF01695.17 EGB03659.1 - 0.049 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 EGB03659.1 - 0.061 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGB03659.1 - 0.074 13.1 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EGB03659.1 - 0.11 12.6 0.1 0.27 11.2 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGB03659.1 - 0.19 11.2 0.1 0.7 9.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Pkinase PF00069.25 EGB03660.1 - 1.2e-48 165.8 0.0 1.6e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03660.1 - 3.6e-26 92.0 0.0 5.2e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB03660.1 - 1.1e-05 25.5 3.7 4.2e-05 23.6 0.3 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB03660.1 - 0.00023 20.1 0.0 0.00039 19.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB03660.1 - 0.0019 17.6 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB03660.1 - 0.01 15.2 0.0 0.027 13.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB03660.1 - 0.055 12.4 0.1 0.089 11.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EGB03660.1 - 0.065 12.8 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 RIO1 family FWWh PF14922.6 EGB03661.1 - 5.1e-16 58.9 0.2 2e-15 57.0 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function Ras PF00071.22 EGB03662.1 - 8e-55 184.9 0.0 9.4e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB03662.1 - 5.3e-33 113.8 0.0 1e-32 112.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB03662.1 - 5.1e-14 52.1 0.0 6.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB03662.1 - 2e-07 31.1 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGB03662.1 - 1e-05 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGB03662.1 - 1.8e-05 24.3 0.0 0.00044 19.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB03662.1 - 0.00029 20.8 0.0 0.021 14.8 0.0 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGB03662.1 - 0.0034 17.8 0.0 0.0064 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EGB03662.1 - 0.0047 16.2 0.1 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 Septin AAA_22 PF13401.6 EGB03662.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGB03662.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SRPRB PF09439.10 EGB03662.1 - 0.021 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 EGB03662.1 - 0.022 14.7 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGB03662.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EGB03662.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MCM PF00493.23 EGB03662.1 - 0.08 12.0 0.5 0.31 10.1 0.0 2.1 3 0 0 3 3 3 0 MCM P-loop domain AAA_24 PF13479.6 EGB03662.1 - 0.087 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGB03662.1 - 0.088 12.6 0.1 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 EGB03662.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Foie-gras_1 PF11817.8 EGB03663.1 - 3.5e-12 46.5 2.8 8e-12 45.3 0.2 2.5 3 0 0 3 3 3 1 Foie gras liver health family 1 TPR_2 PF07719.17 EGB03663.1 - 0.11 12.7 8.0 0.22 11.7 1.9 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Adaptin_N PF01602.20 EGB03665.1 - 5.9e-05 21.8 0.0 6.3e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Radial_spoke PF04712.12 EGB03666.1 - 4.5e-93 312.8 0.5 1.8e-64 218.5 0.3 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein RRM_1 PF00076.22 EGB03668.1 - 1.8e-13 50.1 0.0 2.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB03668.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Tudor-knot PF11717.8 EGB03669.1 - 9.5e-11 41.4 0.1 1.5e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.13 EGB03669.1 - 4.7e-07 29.3 0.0 3.9e-05 23.0 0.0 2.0 1 1 1 2 2 2 2 MRG MBT PF02820.18 EGB03669.1 - 0.033 14.5 0.1 0.056 13.8 0.1 1.3 1 0 0 1 1 1 0 mbt repeat Tudor_3 PF18115.1 EGB03669.1 - 0.085 12.7 0.3 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Abhydrolase_3 PF07859.13 EGB03670.1 - 2e-19 70.3 0.1 2.9e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Nodulin-like PF06813.13 EGB03671.1 - 6.7e-05 22.5 5.7 6.7e-05 22.5 5.7 3.0 3 1 0 3 3 3 2 Nodulin-like PRMT5 PF05185.16 EGB03672.1 - 2.7e-49 167.4 0.0 3.6e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EGB03672.1 - 1.4e-38 132.6 0.0 1.8e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 EGB03672.1 - 2.8e-26 92.3 0.0 2.9e-20 72.6 0.0 2.1 1 1 1 2 2 2 2 PRMT5 TIM barrel domain DUF2499 PF10693.9 EGB03673.1 - 2.2e-35 120.8 5.4 6.3e-35 119.3 5.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3593 PF12159.8 EGB03673.1 - 1e-30 105.6 0.5 4.2e-30 103.6 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3593) DUF5379 PF17350.2 EGB03673.1 - 0.072 13.4 1.6 0.58 10.5 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5379) Put_DNA-bind_N PF06971.13 EGB03673.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus 2OG-FeII_Oxy_2 PF13532.6 EGB03674.1 - 1.1e-31 110.6 0.0 1.2e-31 110.5 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB03674.1 - 0.028 14.9 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 EGB03675.1 - 2.9e-11 43.0 0.0 1e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.11 EGB03675.1 - 0.00013 22.1 32.0 0.00034 20.8 32.0 1.7 1 0 0 1 1 1 1 Fruit fly transformer protein DUF1866 PF08952.11 EGB03675.1 - 0.038 13.9 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Apt1 PF10351.9 EGB03675.1 - 0.043 12.7 6.9 0.051 12.4 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRM_occluded PF16842.5 EGB03675.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Rrn6 PF10214.9 EGB03675.1 - 0.11 10.9 8.0 0.14 10.7 8.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Cupin_8 PF13621.6 EGB03676.1 - 6e-22 78.6 0.0 8.5e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain FKBP_C PF00254.28 EGB03676.1 - 3.1e-12 46.7 0.0 5.4e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase JmjC PF02373.22 EGB03676.1 - 0.0006 20.2 0.0 0.00093 19.6 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGB03676.1 - 0.052 13.0 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 EGB03676.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Cupin Glyco_tranf_2_3 PF13641.6 EGB03677.1 - 1.5e-06 28.3 0.1 3e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGB03677.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Histone PF00125.24 EGB03678.1 - 5.3e-19 68.9 0.4 6.3e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB03678.1 - 1.9e-05 24.8 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB03678.1 - 0.0038 17.7 0.0 0.0059 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB03678.1 - 0.053 13.6 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein CENP-T_C PF15511.6 EGB03679.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB03679.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB03679.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB03679.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB03679.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB03679.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB03679.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGB03679.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Asparaginase PF00710.20 EGB03680.1 - 4.7e-21 75.2 0.1 5.2e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Asparaginase, N-terminal DRTGG PF07085.12 EGB03680.1 - 0.075 12.8 0.6 0.3 10.9 0.3 2.2 2 1 0 2 2 2 0 DRTGG domain SNF2_N PF00176.23 EGB03681.1 - 1.9e-25 89.3 0.0 2e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGB03681.1 - 0.007 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGB03681.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGB03682.1 - 3.1e-11 43.6 0.0 3.6e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGB03682.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PAN_4 PF14295.6 EGB03683.1 - 0.0022 17.9 1.0 0.0066 16.3 1.0 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EGB03683.1 - 0.022 14.7 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 PAN domain GST_C PF00043.25 EGB03684.1 - 9.7e-10 38.5 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB03684.1 - 5.3e-06 26.7 0.0 1.5e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB03684.1 - 3.3e-05 24.2 0.0 0.0001 22.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB03684.1 - 0.00097 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EGB03684.1 - 0.0057 17.0 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EGB03684.1 - 0.0096 16.6 0.0 0.014 16.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 EGB03684.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB03684.1 - 0.084 12.9 0.1 0.26 11.3 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF563 PF04577.14 EGB03685.1 - 1.6e-12 48.0 0.0 3.5e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DnaJ PF00226.31 EGB03686.1 - 1.2e-21 76.6 0.0 1.3e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain EMP24_GP25L PF01105.24 EGB03687.1 - 1.2e-22 80.8 0.1 1.3e-22 80.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4337 PF14235.6 EGB03687.1 - 0.0037 17.4 0.3 0.0051 17.0 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) Synaptobrevin PF00957.21 EGB03687.1 - 0.06 13.1 0.2 0.088 12.6 0.2 1.2 1 0 0 1 1 1 0 Synaptobrevin Ribosomal_S8 PF00410.19 EGB03687.1 - 0.062 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 DUF4372 PF14294.6 EGB03687.1 - 0.1 12.7 0.1 18 5.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) PH PF00169.29 EGB03688.1 - 7e-10 39.4 0.0 1.3e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 EGB03688.1 - 0.00017 22.0 0.1 0.01 16.2 0.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EGB03688.1 - 0.0021 18.3 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3450 PF11932.8 EGB03688.1 - 0.11 11.8 17.3 0.25 10.6 4.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) G6PD_C PF02781.16 EGB03689.1 - 2e-50 171.6 0.0 1.3e-27 96.8 0.0 2.1 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGB03689.1 - 2.6e-47 161.7 0.0 3.8e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DHHC PF01529.20 EGB03690.1 - 2.4e-11 43.9 0.5 2.4e-11 43.9 0.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase B12D PF06522.11 EGB03690.1 - 2.8 7.8 4.2 6.7 6.6 1.6 2.3 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit AP_endonuc_2 PF01261.24 EGB03691.1 - 8.6e-22 77.6 0.8 1.3e-21 77.0 0.3 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel PAC2 PF09754.9 EGB03691.1 - 0.15 12.0 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 PAC2 family Histone PF00125.24 EGB03692.1 - 6.1e-53 178.7 1.1 6.8e-53 178.5 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGB03692.1 - 0.00076 20.1 3.0 0.00098 19.7 3.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGB03692.1 - 0.00088 19.4 0.3 0.0014 18.7 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB03692.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGB03692.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGB03692.1 - 0.032 14.3 0.1 0.057 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone_H2A_C PF16211.5 EGB03693.1 - 7.9e-21 73.5 1.4 2.2e-20 72.1 1.4 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB03693.1 - 1e-11 45.3 0.0 1.2e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB03693.1 - 0.0015 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PH PF00169.29 EGB03694.1 - 2.1e-15 57.1 0.0 3.3e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 EGB03694.1 - 0.00053 19.8 0.3 0.11 12.2 0.2 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 EGB03694.1 - 0.25 11.7 1.7 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain Cdh1_DBD_1 PF18196.1 EGB03694.1 - 4.2 7.7 8.0 18 5.7 2.1 2.6 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 ORC5_C PF14630.6 EGB03695.1 - 9.8e-29 100.8 0.0 1.3e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EGB03695.1 - 4.2e-07 30.5 0.3 1.3e-06 28.9 0.3 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EGB03695.1 - 0.0042 16.8 4.0 0.097 12.4 4.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB03695.1 - 0.056 13.8 0.1 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGB03695.1 - 0.086 12.4 4.0 2.6 7.6 4.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGB03695.1 - 0.1 12.4 0.1 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGB03695.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CAP_N PF01213.19 EGB03695.1 - 1.9 7.9 7.5 4.5 6.7 1.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.32 EGB03696.1 - 5.9e-48 159.8 14.4 5.7e-09 36.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB03696.1 - 1.3e-06 28.7 1.6 3.4 8.0 0.1 4.8 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB03696.1 - 0.00011 21.0 2.7 5.2 5.6 0.0 4.4 3 1 2 5 5 5 3 Nucleoporin Nup120/160 CbiG_N PF11760.8 EGB03696.1 - 0.12 12.4 0.2 17 5.5 0.0 2.8 2 1 1 3 3 3 0 Cobalamin synthesis G N-terminal Aldedh PF00171.22 EGB03697.1 - 2.1e-144 481.5 2.2 2.4e-144 481.3 2.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Chloroa_b-bind PF00504.21 EGB03698.1 - 2.5e-30 106.2 0.0 3.3e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pyr_redox_3 PF13738.6 EGB03699.1 - 8e-70 235.5 0.0 1.3e-69 234.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB03699.1 - 5e-12 45.6 0.5 9.4e-10 38.2 0.1 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB03699.1 - 2.6e-09 36.7 0.0 3.6e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGB03699.1 - 1.3e-08 34.9 10.8 7.5e-06 25.8 2.0 2.7 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB03699.1 - 7.2e-07 29.7 0.2 0.043 14.4 0.2 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGB03699.1 - 7.8e-07 28.8 7.1 4.2e-05 23.1 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGB03699.1 - 1.1e-05 25.5 1.0 2.7e-05 24.2 1.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGB03699.1 - 1.2e-05 24.2 1.4 0.15 10.8 0.8 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 EGB03699.1 - 5e-05 22.7 3.5 0.069 12.4 2.5 3.1 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGB03699.1 - 0.00012 22.2 1.7 0.00069 19.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGB03699.1 - 0.0064 15.8 1.1 0.053 12.8 0.1 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EGB03699.1 - 0.0067 15.5 1.9 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGB03699.1 - 0.074 12.1 0.3 0.15 11.1 0.3 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGB03699.1 - 1.3 8.0 13.2 14 4.7 0.1 3.0 2 1 1 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 EGB03699.1 - 3.6 6.3 8.3 0.83 8.4 0.6 2.6 3 0 0 3 3 3 0 Tryptophan halogenase ketoacyl-synt PF00109.26 EGB03700.1 - 1.4e-25 90.4 1.1 2.1e-25 89.7 1.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03700.1 - 1.9e-07 31.1 0.1 3.7e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HMG_CoA_synt_N PF01154.17 EGB03701.1 - 4e-28 98.4 0.1 4.3e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ECH_1 PF00378.20 EGB03702.1 - 3.6e-17 62.5 0.0 3.8e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB03702.1 - 0.038 13.5 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 EGB03703.1 - 2.8e-33 115.6 8.0 3.9e-33 115.1 8.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03703.1 - 0.0004 20.4 0.1 0.001 19.1 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Helicase_C PF00271.31 EGB03704.1 - 3.7e-20 72.3 0.0 4.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGB03704.1 - 0.0018 17.5 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 EGB03704.1 - 0.22 10.6 0.0 0.44 9.7 0.0 1.5 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Mo25 PF08569.11 EGB03705.1 - 4.2e-95 318.9 1.4 4.8e-95 318.7 1.4 1.0 1 0 0 1 1 1 1 Mo25-like Arm PF00514.23 EGB03705.1 - 0.019 15.0 1.3 4.9 7.3 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat STI1 PF17830.1 EGB03705.1 - 0.074 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 STI1 domain DnaGprimase_HBD PF16730.5 EGB03705.1 - 0.11 12.6 0.3 0.41 10.7 0.0 2.1 3 0 0 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain Pkinase PF00069.25 EGB03706.1 - 1.5e-61 208.1 0.0 2e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03706.1 - 1.7e-27 96.4 0.0 2.3e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB03706.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGB03706.1 - 0.00017 20.7 0.1 0.00066 18.7 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGB03706.1 - 0.1 12.0 0.3 0.49 9.7 0.3 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_8 PF01501.20 EGB03707.1 - 0.00013 21.6 0.0 0.002 17.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGB03707.1 - 0.00038 19.9 0.0 0.00052 19.5 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative TPR_14 PF13428.6 EGB03708.1 - 0.0012 19.5 9.6 0.36 11.8 0.1 6.1 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB03708.1 - 0.013 15.8 0.0 1e+02 3.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB03708.1 - 0.45 10.8 0.0 0.45 10.8 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 EGB03709.1 - 2.3e-29 102.4 0.0 3.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_C50 PF03568.17 EGB03711.1 - 6.4e-49 167.1 0.0 1.5e-48 165.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family C50 GAF_2 PF13185.6 EGB03711.1 - 1.6e-07 31.7 0.1 0.00095 19.5 0.0 5.4 5 0 0 5 5 5 1 GAF domain GAF_3 PF13492.6 EGB03711.1 - 0.016 15.5 0.2 1.1 9.6 0.0 4.0 5 0 0 5 5 5 0 GAF domain S-AdoMet_synt_C PF02773.16 EGB03712.1 - 7.9e-64 213.8 0.2 1.2e-62 210.0 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGB03712.1 - 1.8e-43 147.6 0.1 4.2e-43 146.4 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGB03712.1 - 4.6e-42 142.7 1.5 9.4e-42 141.7 0.6 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EGB03712.1 - 0.081 11.7 0.8 0.51 9.1 0.1 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) KR PF08659.10 EGB03715.1 - 1.4e-29 103.3 0.0 2.4e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB03715.1 - 7.4e-09 35.4 0.0 1.9e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EGB03715.1 - 4.3e-07 29.6 0.0 1.3e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EGB03715.1 - 1.7e-05 24.0 0.0 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 EGB03715.1 - 0.0052 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 EGB03715.1 - 0.015 14.8 0.0 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGB03715.1 - 0.045 12.9 0.0 0.096 11.8 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein AAA PF00004.29 EGB03716.1 - 2.7e-12 47.2 0.0 4.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGB03716.1 - 0.00011 21.6 0.1 0.0059 16.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGB03716.1 - 0.00017 21.8 0.0 0.00028 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGB03716.1 - 0.0088 16.3 0.0 1.7 9.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 EGB03716.1 - 0.0098 15.6 0.3 0.024 14.4 0.3 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGB03716.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGB03716.1 - 0.013 15.9 0.1 0.071 13.4 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 EGB03716.1 - 0.026 14.7 0.1 0.1 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGB03716.1 - 0.029 14.1 0.0 0.66 9.7 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 EGB03716.1 - 0.04 14.3 2.6 0.14 12.5 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 EGB03716.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EGB03716.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGB03716.1 - 0.18 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Ras PF00071.22 EGB03717.1 - 2.7e-46 157.2 0.0 3.1e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB03717.1 - 1.3e-22 80.2 0.0 2.4e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB03717.1 - 3.5e-08 33.1 0.0 4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGB03717.1 - 0.00052 19.6 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB03717.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CPSF_A PF03178.15 EGB03719.1 - 7.3e-39 133.9 0.0 1.4e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 EGB03719.1 - 5.6e-24 84.6 0.0 3.2e-23 82.1 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pkinase PF00069.25 EGB03720.1 - 1.4e-62 211.5 0.0 1.7e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03720.1 - 5.5e-29 101.2 0.0 7.6e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB03720.1 - 0.00037 19.9 0.0 0.0022 17.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGB03720.1 - 0.011 15.1 0.5 0.017 14.5 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB03720.1 - 0.02 13.9 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGB03720.1 - 0.047 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RCDG1 PF15725.5 EGB03720.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein SH3_1 PF00018.28 EGB03721.1 - 5e-12 45.2 0.4 6.1e-06 25.7 0.0 3.2 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 EGB03721.1 - 5.4e-09 35.8 0.4 0.00076 19.3 0.0 3.5 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 EGB03721.1 - 9.6e-06 25.2 0.0 0.002 17.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Pkinase PF00069.25 EGB03722.1 - 9.6e-45 153.0 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03722.1 - 1.5e-28 99.8 0.0 2.1e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB03722.1 - 1.9e-05 24.1 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB03722.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGB03722.1 - 0.045 13.7 0.1 0.71 9.7 0.1 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGB03722.1 - 0.079 12.3 0.2 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bromodomain PF00439.25 EGB03723.1 - 0.0041 17.1 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 Bromodomain WSD PF15613.6 EGB03723.1 - 0.1 13.1 0.0 0.38 11.3 0.0 2.1 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif AAA_lid_3 PF17862.1 EGB03724.1 - 2.3e-11 43.3 0.5 4.4e-11 42.4 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EGB03724.1 - 1.3e-10 41.8 0.0 3.2e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Myb_DNA-binding PF00249.31 EGB03725.1 - 2.1e-08 34.2 0.0 4.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB03725.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4130 PF13566.6 EGB03725.1 - 0.084 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 zf_C2HC_14 PF18574.1 EGB03725.1 - 4.6 7.1 8.1 62 3.5 0.0 2.8 2 0 0 2 2 2 0 C2HC Zing finger domain WD40 PF00400.32 EGB03726.1 - 1e-31 108.5 26.9 3.5e-05 24.5 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB03726.1 - 2.1e-11 44.0 0.0 0.0034 17.7 0.1 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGB03726.1 - 0.00017 21.0 0.1 0.0015 18.0 0.0 2.3 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EGB03726.1 - 0.036 13.0 0.3 1.2 8.0 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGB03726.1 - 0.05 11.9 0.0 0.81 7.9 0.0 2.3 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz cNMP_binding PF00027.29 EGB03727.1 - 5.5e-15 55.2 0.0 8.6e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB03727.1 - 1.3e-07 31.1 13.5 2.2e-07 30.4 13.5 1.3 1 0 0 1 1 1 1 Ion transport protein 7tm_3 PF00003.22 EGB03727.1 - 0.063 13.0 3.2 0.15 11.8 3.2 1.5 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR RNA_pol_Rpb2_6 PF00562.28 EGB03728.1 - 8.6e-118 393.8 0.0 1.3e-117 393.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGB03728.1 - 3.4e-50 170.4 0.0 5e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGB03728.1 - 5.2e-32 110.1 0.2 1.5e-31 108.6 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EGB03728.1 - 1.5e-22 79.7 0.7 3.4e-22 78.5 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGB03728.1 - 5.8e-21 74.4 0.0 1.5e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGB03728.1 - 6.9e-21 74.7 0.2 1.7e-20 73.4 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 EGB03728.1 - 7.1e-08 32.9 1.6 2.3e-07 31.3 1.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Metallophos PF00149.28 EGB03729.1 - 2.6e-33 116.2 0.0 3.2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3 PF00041.21 EGB03731.1 - 0.016 15.6 0.0 2.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Fibronectin type III domain cNMP_binding PF00027.29 EGB03732.1 - 3.1e-45 152.2 0.0 2.7e-21 75.4 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF5586 PF17824.1 EGB03732.1 - 0.00049 19.3 0.3 0.00089 18.5 0.1 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5586) DUF5582 PF17819.1 EGB03732.1 - 0.0039 17.7 1.9 0.0064 17.0 0.2 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5582) MCM PF00493.23 EGB03734.1 - 8.6e-98 325.9 0.1 1.4e-97 325.2 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGB03734.1 - 1.4e-35 121.9 0.1 3.2e-35 120.7 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGB03734.1 - 3.5e-25 88.3 0.6 9.7e-25 86.8 0.6 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGB03734.1 - 1e-13 51.7 0.9 2.3e-13 50.6 0.9 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGB03734.1 - 0.00014 21.3 0.0 0.00081 18.8 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB03734.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB03734.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EGB03734.1 - 0.26 12.0 5.2 0.081 13.6 1.2 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Vps16_N PF04841.13 EGB03735.1 - 3.2e-52 177.7 0.0 4.5e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EGB03735.1 - 4.3e-12 45.7 0.6 5.9e-12 45.3 0.6 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EGB03735.1 - 0.00077 19.7 0.0 0.14 12.5 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Adap_comp_sub PF00928.21 EGB03736.1 - 2.1e-90 302.7 0.0 2.6e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGB03736.1 - 0.04 13.8 0.6 0.14 12.0 0.5 1.9 1 1 1 2 2 2 0 Clathrin adaptor complex small chain AAA_8 PF12780.7 EGB03737.1 - 2.3e-99 331.9 0.0 5.7e-98 327.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGB03737.1 - 1e-96 323.8 0.1 3.9e-96 321.9 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGB03737.1 - 2.4e-61 206.4 0.0 6.4e-61 205.0 0.0 1.8 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_9 PF12781.7 EGB03737.1 - 2.1e-52 177.4 4.9 1.9e-30 105.7 4.0 2.6 2 0 0 2 2 2 2 ATP-binding dynein motor region MT PF12777.7 EGB03737.1 - 2.2e-46 158.5 12.9 4.3e-46 157.5 12.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGB03737.1 - 3.2e-41 140.1 0.0 8.1e-40 135.6 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EGB03737.1 - 2.2e-30 105.6 0.6 1.3e-29 103.1 0.6 2.3 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 EGB03737.1 - 8.8e-27 93.7 0.0 2.6e-26 92.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGB03737.1 - 3.5e-11 43.3 0.0 4e-08 33.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGB03737.1 - 2.9e-05 24.2 0.0 0.00014 22.0 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EGB03737.1 - 0.00088 19.7 4.5 0.018 15.5 0.2 4.3 3 1 1 4 4 4 1 AAA ATPase domain T2SSE PF00437.20 EGB03737.1 - 0.0027 16.8 0.4 0.0068 15.5 0.4 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGB03737.1 - 0.0055 17.0 1.4 0.05 13.9 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 EGB03737.1 - 0.007 16.8 0.1 0.038 14.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EGB03737.1 - 0.0071 15.7 0.4 0.026 13.9 0.1 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family UPF0242 PF06785.11 EGB03737.1 - 0.012 15.7 0.1 0.012 15.7 0.1 2.9 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus Vps5 PF09325.10 EGB03737.1 - 0.013 15.0 0.2 0.013 15.0 0.2 2.1 2 0 0 2 2 1 0 Vps5 C terminal like Sigma54_activat PF00158.26 EGB03737.1 - 0.025 14.3 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGB03737.1 - 0.095 12.7 0.0 0.38 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain COG2 PF06148.11 EGB03737.1 - 0.11 12.5 9.7 0.0095 16.0 2.3 2.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mg_chelatase PF01078.21 EGB03737.1 - 0.14 11.5 0.2 0.81 9.0 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF3450 PF11932.8 EGB03737.1 - 1.6 8.0 13.8 0.53 9.5 2.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 EGB03737.1 - 1.9 8.8 5.5 0.33 11.2 0.6 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) SHE3 PF17078.5 EGB03737.1 - 2.1 8.0 8.7 0.62 9.7 0.6 2.7 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4201 PF13870.6 EGB03737.1 - 3.2 7.5 8.6 2.2 8.0 2.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Pkinase PF00069.25 EGB03738.1 - 4.5e-60 203.2 0.0 5.1e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03738.1 - 9.1e-38 130.0 0.0 1.2e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB03738.1 - 4.8e-05 22.3 0.0 6.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB03738.1 - 0.0011 18.4 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGB03738.1 - 0.0016 17.5 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB03738.1 - 0.0073 16.2 0.1 0.014 15.3 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGB03738.1 - 0.042 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SRP68 PF16969.5 EGB03739.1 - 1.9e-29 103.1 6.0 5e-17 62.1 1.3 2.0 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 FWWh PF14922.6 EGB03740.1 - 1.1e-41 142.2 0.0 1.8e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function cNMP_binding PF00027.29 EGB03741.1 - 7.2e-29 99.7 0.0 3.2e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PI3_PI4_kinase PF00454.27 EGB03742.1 - 1.3e-42 146.3 0.0 1.1e-41 143.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGB03742.1 - 1.2e-28 99.7 1.5 1.5e-28 99.5 0.2 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EGB03742.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) SNF2_N PF00176.23 EGB03743.1 - 2.8e-12 46.0 0.0 4.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGB03743.1 - 4.2e-06 26.9 0.0 6.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB03743.1 - 2.1e-05 24.3 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 EGB03743.1 - 0.0004 20.0 0.7 0.00066 19.3 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_34 PF13872.6 EGB03743.1 - 0.016 14.1 0.3 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 AAA_19 PF13245.6 EGB03743.1 - 0.035 14.4 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGB03743.1 - 0.082 12.1 0.5 0.098 11.9 0.0 1.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ARL2_Bind_BART PF11527.8 EGB03744.1 - 2.3e-17 63.1 0.0 3.7e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART WW PF00397.26 EGB03744.1 - 1.4e-07 31.5 0.3 3.8e-07 30.1 0.3 1.8 1 0 0 1 1 1 1 WW domain Kinesin PF00225.23 EGB03744.1 - 0.023 13.7 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain GvpL_GvpF PF06386.11 EGB03745.1 - 0.0058 16.6 0.8 0.012 15.6 0.1 1.8 2 0 0 2 2 2 1 Gas vesicle synthesis protein GvpL/GvpF Acyl_transf_3 PF01757.22 EGB03746.1 - 5.1e-11 42.2 7.2 5.1e-11 42.2 7.2 1.9 1 1 1 2 2 2 1 Acyltransferase family Sulfotransfer_3 PF13469.6 EGB03746.1 - 0.00047 20.6 0.1 0.012 16.0 0.1 2.4 1 1 0 1 1 1 1 Sulfotransferase family TMEM189_B_dmain PF10520.9 EGB03747.1 - 9.3e-17 61.7 0.8 1.5e-16 61.1 0.8 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain Ribosomal_60s PF00428.19 EGB03748.1 - 4.1 8.1 6.1 9.6 6.9 6.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Methyltransf_11 PF08241.12 EGB03749.1 - 1.2e-08 35.5 0.0 2.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03749.1 - 1.3e-07 31.6 0.1 2.9e-07 30.4 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03749.1 - 0.00016 22.4 0.0 0.00047 20.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB03749.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03749.1 - 0.0017 19.0 0.0 0.0087 16.8 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB03749.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family VKG_Carbox PF05090.14 EGB03751.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Methyltransf_24 PF13578.6 EGB03752.1 - 0.0024 18.9 0.2 0.0024 18.9 0.2 3.1 3 0 0 3 3 3 1 Methyltransferase domain Pkinase_Tyr PF07714.17 EGB03753.1 - 1.3e-05 24.6 0.0 2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB03753.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGB03753.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Methyltransf_23 PF13489.6 EGB03756.1 - 1.8e-15 57.2 0.0 1.7e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain DUF563 PF04577.14 EGB03756.1 - 4e-14 53.2 0.0 7.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Methyltransf_11 PF08241.12 EGB03756.1 - 8e-08 32.8 0.0 2.3e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03756.1 - 3.5e-07 30.9 0.0 1.7e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03756.1 - 2.8e-06 27.9 0.0 1.4e-05 25.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB03756.1 - 0.00052 19.8 0.0 0.014 15.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_14 PF08484.11 EGB03756.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Ubie_methyltran PF01209.18 EGB03756.1 - 0.29 10.4 0.0 2.9 7.1 0.0 2.1 1 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family HNH_3 PF13392.6 EGB03757.1 - 2.1e-14 53.0 1.4 3e-14 52.5 1.4 1.3 1 0 0 1 1 1 1 HNH endonuclease NUMOD4 PF07463.11 EGB03757.1 - 1.8e-07 31.2 0.2 4.9e-07 29.8 0.2 1.7 1 0 0 1 1 1 1 NUMOD4 motif AP2 PF00847.20 EGB03757.1 - 1.8e-06 28.1 0.2 1.8e-06 28.1 0.2 2.0 3 0 0 3 3 3 1 AP2 domain Med15 PF09606.10 EGB03758.1 - 0.045 12.4 45.0 0.055 12.2 45.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 EGB03758.1 - 0.5 10.3 29.8 0.66 9.9 29.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCM2_N PF12619.8 EGB03759.1 - 0.02 15.2 0.5 0.02 15.2 0.5 2.3 2 1 1 3 3 3 0 Mini-chromosome maintenance protein 2 Methyltransf_11 PF08241.12 EGB03760.1 - 0.00056 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03760.1 - 0.015 15.2 0.0 0.041 13.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_21 PF05050.12 EGB03761.1 - 3.3e-07 30.5 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Acetyltransf_6 PF13480.7 EGB03763.1 - 1.1e-11 45.1 8.0 1.1e-11 45.1 8.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FemAB PF02388.16 EGB03763.1 - 3.9e-07 29.3 2.5 2.1e-05 23.6 1.0 2.1 1 1 1 2 2 2 2 FemAB family PorB PF11565.8 EGB03764.1 - 1.3 9.4 5.1 3.1 8.3 5.1 1.6 1 0 0 1 1 1 0 Alpha helical Porin B Methyltransf_23 PF13489.6 EGB03766.1 - 6e-06 26.2 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03766.1 - 3.7e-05 24.4 0.1 9.6e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB03766.1 - 9.4e-05 23.0 0.1 0.00025 21.6 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03766.1 - 0.016 16.0 0.0 0.034 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 EGB03768.1 - 1.5e-13 51.7 0.4 3.4e-13 50.5 0.4 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EGB03768.1 - 0.0086 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Pkinase PF00069.25 EGB03770.1 - 1.1e-44 152.8 0.0 1.4e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03770.1 - 1.7e-16 60.3 0.0 2.9e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB03770.1 - 0.0024 17.2 0.0 0.0063 15.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like ZapB PF06005.12 EGB03770.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TPR_14 PF13428.6 EGB03770.1 - 0.015 16.0 1.2 0.015 16.0 1.2 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat LRR_8 PF13855.6 EGB03771.1 - 1.5e-30 104.8 21.6 6.7e-09 35.4 0.0 6.3 6 0 0 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EGB03771.1 - 1e-21 76.6 24.5 8.9e-05 22.8 2.3 7.6 5 3 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB03771.1 - 8.3e-10 37.9 24.7 0.24 11.6 0.3 9.3 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 EGB03771.1 - 1.6e-07 30.9 19.3 0.21 12.3 0.5 8.5 8 2 1 9 9 9 3 Leucine Rich Repeat LRR_9 PF14580.6 EGB03771.1 - 0.023 14.2 6.0 2.4 7.6 0.3 3.5 2 2 1 3 3 3 0 Leucine-rich repeat adh_short PF00106.25 EGB03772.1 - 2.9e-25 88.9 0.6 4.9e-25 88.1 0.6 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB03772.1 - 1.4e-18 67.3 4.2 4.5e-17 62.4 4.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGB03772.1 - 2.4e-08 33.8 0.1 3.3e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGB03772.1 - 1e-05 25.6 0.8 1.6e-05 24.9 0.2 1.5 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EGB03772.1 - 0.00026 20.5 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGB03772.1 - 0.004 16.3 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain ApbA PF02558.16 EGB03772.1 - 0.019 14.6 0.5 0.05 13.2 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_transf_4 PF13439.6 EGB03772.1 - 0.034 14.1 0.1 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Polysacc_synt_2 PF02719.15 EGB03772.1 - 0.045 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 EGB03772.1 - 0.069 13.7 0.5 0.14 12.7 0.3 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Arg_repressor PF01316.21 EGB03772.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain O-FucT PF10250.9 EGB03773.1 - 3.9e-10 40.0 0.2 8.3e-07 29.0 0.1 2.1 1 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase GRP PF07172.11 EGB03773.1 - 2.2 9.0 16.6 4.8 7.9 16.6 1.5 1 0 0 1 1 1 0 Glycine rich protein family Pinin_SDK_N PF04697.13 EGB03773.1 - 5.1 7.7 8.8 4 8.1 6.7 1.8 2 0 0 2 2 2 0 pinin/SDK conserved region XPG_N PF00752.17 EGB03774.1 - 9.7e-22 77.4 0.0 2.8e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain Sulfotransfer_1 PF00685.27 EGB03775.1 - 1.4e-15 57.5 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB03775.1 - 1.1e-05 25.9 0.1 2.1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Tctex-1 PF03645.13 EGB03777.1 - 6.4e-06 26.3 0.0 8.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family cNMP_binding PF00027.29 EGB03778.1 - 5.9e-41 138.5 0.1 3.7e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Acetyltransf_1 PF00583.25 EGB03779.1 - 1e-05 25.7 0.0 3.4e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family AA_kinase PF00696.28 EGB03779.1 - 0.00014 21.6 0.4 0.00022 20.9 0.4 1.3 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_7 PF13508.7 EGB03779.1 - 0.00087 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 EGB03781.1 - 4.3e-08 32.7 0.0 3.8e-06 26.4 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB03781.1 - 0.00022 20.6 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGB03781.1 - 0.0046 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EGB03781.1 - 0.082 13.4 0.4 12 6.4 0.2 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EGB03781.1 - 0.11 12.5 0.2 0.95 9.4 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Cyt-b5 PF00173.28 EGB03782.1 - 5.2e-06 26.5 0.0 9.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Imm51 PF15595.6 EGB03782.1 - 0.029 14.3 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 51 RVT_1 PF00078.27 EGB03782.1 - 0.038 13.5 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 EGB03783.1 - 1.8e-44 152.0 2.9 8.8e-44 149.7 2.9 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain APG5 PF04106.12 EGB03783.1 - 0.06 12.9 0.1 0.3 10.6 0.0 1.9 1 1 1 2 2 2 0 Autophagy protein Apg5 EGF_2 PF07974.13 EGB03784.1 - 2.2e-15 56.7 54.8 3.4e-05 24.1 3.5 5.2 4 1 0 4 4 4 4 EGF-like domain Laminin_EGF PF00053.24 EGB03784.1 - 5.4e-09 36.1 38.0 0.0018 18.3 2.4 4.3 3 1 1 4 4 4 4 Laminin EGF domain EGF PF00008.27 EGB03784.1 - 0.00056 20.2 48.2 0.098 13.0 4.1 6.0 7 0 0 7 7 7 4 EGF-like domain hEGF PF12661.7 EGB03784.1 - 0.0034 18.0 1.7 0.0034 18.0 1.7 6.3 7 0 0 7 7 7 2 Human growth factor-like EGF Phage_B PF02304.15 EGB03784.1 - 0.97 9.8 4.1 0.25 11.7 0.4 1.8 2 0 0 2 2 2 0 Scaffold protein B DSL PF01414.19 EGB03784.1 - 1.1 9.6 0.1 0.71 10.2 3.9 4.8 5 0 0 5 5 5 0 Delta serrate ligand Sel1 PF08238.12 EGB03786.1 - 4.2e-17 62.2 10.1 0.0015 19.2 0.1 6.0 6 1 0 6 6 6 4 Sel1 repeat NDK PF00334.19 EGB03788.1 - 2.3e-31 108.6 0.0 4.1e-23 81.9 0.0 2.4 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Glyco_transf_41 PF13844.6 EGB03789.1 - 7e-88 295.1 0.0 3.1e-46 157.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 EGB03789.1 - 4.5e-83 272.7 31.5 2.2e-13 49.7 1.0 12.9 4 2 9 13 13 13 11 TPR repeat TPR_1 PF00515.28 EGB03789.1 - 4.1e-82 266.9 31.5 6e-10 38.5 0.1 13.3 13 1 0 13 13 13 10 Tetratricopeptide repeat TPR_2 PF07719.17 EGB03789.1 - 1.6e-68 221.3 36.9 9.4e-08 31.6 0.1 13.6 13 1 0 13 13 13 10 Tetratricopeptide repeat TPR_17 PF13431.6 EGB03789.1 - 1.5e-55 181.6 22.6 2.3e-05 24.4 0.0 12.4 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_8 PF13181.6 EGB03789.1 - 1.1e-53 174.9 18.9 6.9e-06 25.9 0.0 11.8 13 0 0 13 13 11 10 Tetratricopeptide repeat TPR_7 PF13176.6 EGB03789.1 - 2.2e-41 136.8 27.7 1.8e-05 24.4 0.0 12.4 13 1 1 14 14 12 9 Tetratricopeptide repeat TPR_16 PF13432.6 EGB03789.1 - 5.2e-40 135.8 39.6 1.6e-08 35.0 0.2 9.5 6 3 2 9 9 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 EGB03789.1 - 3.1e-36 120.9 29.1 3.6e-06 27.3 0.5 12.2 3 2 9 12 12 12 9 Tetratricopeptide repeat TPR_12 PF13424.6 EGB03789.1 - 1e-35 121.8 46.5 6.8e-10 39.1 1.4 9.7 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGB03789.1 - 4.6e-32 110.4 28.0 7e-10 39.3 3.7 8.4 6 1 2 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 EGB03789.1 - 1.3e-25 88.5 54.7 0.0045 16.8 1.0 12.6 11 1 1 12 12 12 8 Tetratricopeptide repeat TPR_6 PF13174.6 EGB03789.1 - 7.4e-13 48.2 19.7 0.58 10.9 0.0 11.3 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB03789.1 - 6.4e-12 45.5 24.6 0.0043 17.2 0.1 7.3 2 1 5 8 8 8 6 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 EGB03789.1 - 5.1e-09 36.0 15.6 0.0043 16.6 0.0 6.0 7 0 0 7 7 7 3 Est1 DNA/RNA binding domain TPR_4 PF07721.14 EGB03789.1 - 9.6e-08 32.0 35.9 0.06 14.0 1.8 10.2 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB03789.1 - 3.2e-06 26.8 17.7 0.0044 16.4 2.7 4.6 2 1 0 3 3 3 2 MalT-like TPR region TPR_15 PF13429.6 EGB03789.1 - 5.5e-06 25.8 6.5 5 6.2 0.8 6.2 1 1 3 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 EGB03789.1 - 1.6e-05 24.0 0.6 5.7 5.7 0.1 4.4 3 1 2 5 5 5 1 NMDA receptor-regulated protein 1 FAT PF02259.23 EGB03789.1 - 2.2e-05 23.9 0.5 8 5.6 0.0 5.1 1 1 1 5 5 5 0 FAT domain BTAD PF03704.17 EGB03789.1 - 9.2e-05 22.9 17.5 0.022 15.2 0.0 5.3 4 2 1 5 5 5 2 Bacterial transcriptional activator domain TPR_21 PF09976.9 EGB03789.1 - 0.0023 17.7 3.6 14 5.3 0.0 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain SNAP PF14938.6 EGB03789.1 - 0.026 14.0 10.2 0.85 9.0 0.3 4.7 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP RisS_PPD PF16524.5 EGB03789.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS DUF4810 PF16068.5 EGB03789.1 - 0.088 13.4 1.0 79 3.9 0.1 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4810) DUF3856 PF12968.7 EGB03789.1 - 0.43 10.6 3.0 7.9 6.6 0.0 4.2 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 EGB03789.1 - 0.47 10.8 3.3 37 4.9 0.0 5.1 6 0 0 6 6 4 0 PPR repeat ANAPC3 PF12895.7 EGB03789.1 - 1 9.6 17.7 0.17 12.2 1.9 4.9 3 3 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EGB03789.1 - 1.9 8.1 7.3 2.4 7.8 0.1 4.3 4 2 3 7 7 6 0 26S proteasome subunit RPN7 Optomotor-blind PF11078.8 EGB03789.1 - 2.7 8.6 12.0 0.91 10.1 0.4 4.7 2 1 2 4 4 4 0 Optomotor-blind protein N-terminal region RPN2_C PF18004.1 EGB03790.1 - 1.4e-28 99.9 0.5 1.8e-28 99.5 0.5 1.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGB03790.1 - 3.3e-15 55.6 3.3 2e-09 37.4 0.0 3.7 3 0 0 3 3 3 2 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGB03790.1 - 2.9e-13 50.0 0.0 6.7e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 EGB03790.1 - 1.4e-07 31.2 1.9 0.3 11.4 0.2 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EGB03790.1 - 0.00024 21.5 2.2 0.14 12.7 0.1 3.4 1 1 2 3 3 3 2 HEAT-like repeat NTR PF01759.21 EGB03790.1 - 0.035 13.9 0.3 0.055 13.3 0.3 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Arm PF00514.23 EGB03790.1 - 0.044 13.8 0.5 9.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGB03791.1 - 3.6e-114 382.2 6.1 5.4e-114 381.6 6.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGB03791.1 - 4.5e-44 150.2 1.0 1.2e-43 148.9 1.0 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGB03791.1 - 4.8e-30 104.1 0.0 1.3e-29 102.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGB03791.1 - 1.3e-14 54.3 11.2 3.6e-08 33.7 1.3 5.8 2 2 4 6 6 6 2 HEAT repeats Cnd1 PF12717.7 EGB03791.1 - 9.8e-12 45.2 10.0 6.1e-06 26.4 0.1 4.2 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGB03791.1 - 4.6e-05 23.3 11.0 0.84 10.1 0.2 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EGB03791.1 - 0.0015 19.0 13.3 0.61 10.7 4.2 4.3 4 0 0 4 4 4 2 HEAT-like repeat Coatomer_b_Cpla PF14806.6 EGB03791.1 - 0.0042 17.1 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform CM_1 PF07736.11 EGB03791.1 - 0.054 13.9 1.1 3.9 7.9 0.1 3.0 2 1 1 3 3 3 0 Chorismate mutase type I Phage_holin_3_2 PF04550.12 EGB03791.1 - 0.62 10.6 2.4 11 6.6 0.0 3.6 4 0 0 4 4 4 0 Phage holin family 2 Kinesin PF00225.23 EGB03792.1 - 5.3e-103 344.4 1.2 7.4e-103 344.0 1.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB03792.1 - 4.7e-20 72.0 0.0 1.1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding LRR_9 PF14580.6 EGB03793.1 - 1.4e-31 109.3 12.6 6.9e-11 42.0 0.5 5.9 2 1 4 6 6 6 6 Leucine-rich repeat LRR_4 PF12799.7 EGB03793.1 - 2.3e-29 101.0 52.4 3.7e-08 33.5 4.8 9.2 5 3 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB03793.1 - 4.9e-22 77.5 59.0 6.9e-06 25.7 2.8 9.0 5 2 1 8 8 8 7 Leucine rich repeat LRR_6 PF13516.6 EGB03793.1 - 1.3e-05 24.8 38.4 0.42 10.8 1.5 10.7 11 0 0 11 11 11 3 Leucine Rich repeat LRR_5 PF13306.6 EGB03793.1 - 0.013 15.4 0.9 2.6 8.0 0.0 3.2 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) O-FucT PF10250.9 EGB03795.1 - 1e-09 38.6 0.3 9.3e-07 28.8 0.1 2.1 1 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase ARL2_Bind_BART PF11527.8 EGB03797.1 - 1.8e-17 63.5 0.0 2.8e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART WW PF00397.26 EGB03797.1 - 1.4e-07 31.5 0.3 3.8e-07 30.1 0.3 1.8 1 0 0 1 1 1 1 WW domain Kinesin PF00225.23 EGB03797.1 - 0.023 13.7 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain DUF285 PF03382.14 EGB03798.1 - 0.00096 18.9 0.0 0.003 17.3 0.0 1.6 1 1 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 Abhydrolase_6 PF12697.7 EGB03799.1 - 8.8e-06 26.5 5.6 1.5e-05 25.7 5.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB03799.1 - 9.8e-05 22.1 0.5 0.00082 19.1 0.2 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold PP-binding PF00550.25 EGB03800.1 - 4.4e-07 30.2 0.0 1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PDZ_6 PF17820.1 EGB03800.1 - 0.00026 20.8 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain ketoacyl-synt PF00109.26 EGB03801.1 - 2e-23 83.3 2.5 2.5e-23 83.0 2.5 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ketoacyl-synt PF00109.26 EGB03802.1 - 2.4e-29 102.7 6.6 2.6e-29 102.5 6.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EGB03802.1 - 0.006 16.0 0.4 0.007 15.8 0.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain HMG_CoA_synt_N PF01154.17 EGB03803.1 - 1.9e-24 86.5 0.1 2.1e-24 86.3 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ADH_N PF08240.12 EGB03804.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGB03804.1 - 0.0032 17.5 0.3 0.0062 16.5 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.26 EGB03805.1 - 3e-27 95.8 9.8 3.9e-27 95.4 9.8 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03805.1 - 0.01 15.9 0.4 0.027 14.5 0.0 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB03805.1 - 0.019 14.3 1.2 0.025 14.0 1.2 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 EGB03806.1 - 3.8e-27 95.5 9.8 5.2e-27 95.0 9.8 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03806.1 - 8.1e-07 29.1 0.7 1.5e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB03806.1 - 0.022 14.1 1.2 0.03 13.7 1.2 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain EF-hand_1 PF00036.32 EGB03807.1 - 0.028 14.0 0.1 0.058 13.0 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EGB03807.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EGB03807.1 - 0.33 10.5 1.6 0.48 10.0 0.1 1.9 2 0 0 2 2 2 0 EF hand ketoacyl-synt PF00109.26 EGB03808.1 - 6.7e-21 75.0 9.6 1e-20 74.4 9.6 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03808.1 - 7.8e-18 64.6 0.2 1.7e-17 63.5 0.2 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain AMP-binding PF00501.28 EGB03809.1 - 2.7e-38 131.7 0.1 8.8e-27 93.7 0.0 2.6 1 1 1 2 2 2 2 AMP-binding enzyme Ketoacyl-synt_C PF02801.22 EGB03809.1 - 1.1e-06 28.6 7.5 0.0058 16.6 0.6 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EGB03809.1 - 0.024 15.0 0.0 0.077 13.4 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Condensation PF00668.20 EGB03809.1 - 0.025 13.3 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Condensation domain ketoacyl-synt PF00109.26 EGB03810.1 - 2.7e-20 73.0 3.9 3.8e-20 72.6 3.9 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03810.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain AMP-binding PF00501.28 EGB03811.1 - 1.2e-17 63.7 0.6 1.3e-17 63.5 0.6 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGB03812.1 - 1.5e-07 31.3 0.2 1.6e-07 31.2 0.2 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ECH_1 PF00378.20 EGB03813.1 - 1.9e-28 99.5 0.0 2.1e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB03813.1 - 5e-06 26.2 0.0 5.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Trehalose_PPase PF02358.16 EGB03813.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Trehalose-phosphatase Ketoacyl-synt_C PF02801.22 EGB03814.1 - 2.7e-14 53.2 1.8 2.9e-14 53.1 1.8 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EGB03815.1 - 0.0028 18.0 0.3 0.97 9.8 0.0 2.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site ABC1 PF03109.16 EGB03817.1 - 9.7e-11 41.9 0.0 1.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 ABC1 family RGS PF00615.19 EGB03818.1 - 8.2e-06 26.1 0.6 1.3e-05 25.4 0.6 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain ketoacyl-synt PF00109.26 EGB03820.1 - 3e-12 46.7 3.3 3.3e-12 46.5 3.3 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF5455 PF17537.2 EGB03820.1 - 0.027 14.9 1.1 0.031 14.7 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5455) CD20 PF04103.15 EGB03820.1 - 0.028 14.5 4.5 0.031 14.4 4.5 1.0 1 0 0 1 1 1 0 CD20-like family SLATT_6 PF18169.1 EGB03820.1 - 0.055 13.1 1.4 0.06 12.9 1.4 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 SLATT_5 PF18160.1 EGB03820.1 - 0.95 8.7 4.1 1.1 8.6 4.1 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 HMG_CoA_synt_N PF01154.17 EGB03821.1 - 6.9e-22 78.1 0.1 7.5e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PP-binding PF00550.25 EGB03822.1 - 1.4e-10 41.4 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 EGB03822.1 - 1.2e-06 28.3 0.5 2.1e-06 27.5 0.5 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ECH_1 PF00378.20 EGB03822.1 - 0.005 16.2 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase zf-PARP PF00645.18 EGB03824.1 - 1.2e-10 42.0 2.6 2.7e-10 41.0 2.6 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region TRAP-gamma PF07074.12 EGB03824.1 - 0.022 14.3 0.3 0.37 10.3 0.1 2.3 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) HSF_DNA-bind PF00447.17 EGB03824.1 - 0.024 15.3 0.0 0.073 13.7 0.0 2.0 1 0 0 1 1 1 0 HSF-type DNA-binding AKNA PF12443.8 EGB03824.1 - 0.1 13.3 0.4 0.27 11.9 0.0 1.8 2 0 0 2 2 2 0 AT-hook-containing transcription factor Ribosom_S30AE_C PF16321.5 EGB03827.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus SIR2 PF02146.17 EGB03828.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Sir2 family Rnk_N PF14760.6 EGB03833.1 - 8.4 7.0 6.5 9.6 6.8 0.1 3.5 4 0 0 4 4 4 0 Rnk N-terminus C2 PF00168.30 EGB03836.1 - 0.13 12.6 0.1 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 C2 domain Cupin_4 PF08007.12 EGB03837.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein NodS PF05401.11 EGB03837.1 - 0.073 12.7 0.3 5.2 6.6 0.1 2.4 2 0 0 2 2 2 0 Nodulation protein S (NodS) Prok-RING_4 PF14447.6 EGB03838.1 - 0.0063 16.3 3.5 0.0063 16.3 3.5 3.0 2 1 2 4 4 4 1 Prokaryotic RING finger family 4 PhnA_Zn_Ribbon PF08274.12 EGB03838.1 - 0.017 15.1 0.0 0.017 15.1 0.0 3.1 3 1 0 3 3 3 0 PhnA Zinc-Ribbon NOB1_Zn_bind PF08772.11 EGB03838.1 - 4 7.7 11.2 0.15 12.2 1.8 2.6 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like PARP PF00644.20 EGB03840.1 - 1.3e-17 64.1 0.0 2.6e-17 63.1 0.0 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PhnA_Zn_Ribbon PF08274.12 EGB03842.1 - 0.019 14.9 0.0 0.019 14.9 0.0 4.6 5 1 0 5 5 5 0 PhnA Zinc-Ribbon zf-UDP PF14569.6 EGB03842.1 - 0.92 9.7 9.7 3 8.0 3.4 3.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 EGB03842.1 - 1 9.2 11.6 0.52 10.2 1.0 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGB03842.1 - 5.6 6.9 34.1 0.58 10.1 9.9 5.1 5 1 1 6 6 6 0 Prokaryotic RING finger family 4 Neur_chan_LBD PF02931.23 EGB03843.1 - 6.7e-07 29.0 1.9 1.2e-06 28.2 1.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 EGB03843.1 - 0.44 10.5 11.2 0.058 13.5 3.1 2.4 1 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_transf_8 PF01501.20 EGB03845.1 - 1.8e-05 24.4 0.3 0.00053 19.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 RAP PF08373.10 EGB03846.1 - 1.2e-09 38.2 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain RYDR_ITPR PF01365.21 EGB03846.1 - 3.4e-09 36.4 0.0 7.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 RIH domain EF-hand_6 PF13405.6 EGB03846.1 - 7.4e-09 34.8 0.0 0.00012 21.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB03846.1 - 2.2e-08 33.1 0.1 0.00016 21.0 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB03846.1 - 5.6e-08 31.9 0.3 0.0053 16.2 0.3 2.7 2 0 0 2 2 2 2 EF hand Ion_trans PF00520.31 EGB03846.1 - 9e-06 25.1 7.0 0.00062 19.1 3.3 2.3 2 0 0 2 2 2 2 Ion transport protein Ins145_P3_rec PF08709.11 EGB03846.1 - 3e-05 23.3 0.0 6.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Cellulase PF00150.18 EGB03846.1 - 7.8e-05 22.2 0.5 0.00014 21.4 0.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EF-hand_7 PF13499.6 EGB03846.1 - 0.00017 22.0 0.0 0.073 13.5 0.0 2.5 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB03846.1 - 0.0032 17.3 0.1 0.0098 15.7 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair DUF2726 PF10881.8 EGB03846.1 - 0.083 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) MIR PF02815.19 EGB03846.1 - 0.21 11.4 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 MIR domain FG-GAP_2 PF14312.6 EGB03847.1 - 4.1e-76 251.1 38.2 2.7e-16 59.5 1.4 6.2 6 0 0 6 6 6 6 FG-GAP repeat BNR_2 PF13088.6 EGB03847.1 - 1.2e-08 34.6 0.1 0.00013 21.4 0.1 2.5 1 1 1 2 2 2 2 BNR repeat-like domain PSII_BNR PF14870.6 EGB03847.1 - 1.4e-05 24.5 7.1 0.0019 17.5 0.2 3.8 1 1 0 3 3 3 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 EGB03847.1 - 9.6e-05 21.8 18.7 0.43 10.8 0.6 5.0 4 0 0 4 4 4 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EGB03847.1 - 0.00037 19.4 16.2 0.69 8.6 0.7 4.0 2 2 1 4 4 4 4 Sortilin, neurotensin receptor 3, Kelch_4 PF13418.6 EGB03847.1 - 2.1 8.4 4.9 7.8 6.6 0.3 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Radial_spoke_3 PF06098.11 EGB03848.1 - 4.3e-103 344.5 13.1 5e-103 344.3 13.1 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 AAA_32 PF13654.6 EGB03848.1 - 0.016 14.0 5.8 0.031 13.1 5.8 1.4 1 1 0 1 1 1 0 AAA domain zf-MYND PF01753.18 EGB03849.1 - 6.3e-10 39.0 15.8 6.3e-10 39.0 15.8 3.9 4 0 0 4 4 4 1 MYND finger YHYH PF14240.6 EGB03849.1 - 0.026 14.5 2.1 2.8 7.8 0.1 3.2 1 1 0 2 2 2 0 YHYH protein TPR_12 PF13424.6 EGB03849.1 - 0.061 13.6 0.5 0.4 11.0 0.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 EGB03849.1 - 0.47 10.8 11.1 2.4 8.5 11.1 2.3 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PFK PF00365.20 EGB03850.1 - 1.3e-36 126.4 0.0 2.4e-36 125.5 0.0 1.4 1 1 0 1 1 1 1 Phosphofructokinase CoA_binding_2 PF13380.6 EGB03850.1 - 0.13 12.7 0.1 4.9 7.7 0.0 2.7 3 0 0 3 3 3 0 CoA binding domain DSBA PF01323.20 EGB03851.1 - 5.7e-26 91.5 0.1 6.3e-26 91.3 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain ScdA_N PF04405.14 EGB03851.1 - 0.02 14.5 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) DUF1376 PF07120.11 EGB03851.1 - 0.16 12.3 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) Pkinase PF00069.25 EGB03853.1 - 2.5e-50 171.3 0.0 2.8e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03853.1 - 8.3e-24 84.3 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AIG1 PF04548.16 EGB03854.1 - 6.9e-14 51.7 0.0 8.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EGB03854.1 - 2.3e-10 40.6 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGB03854.1 - 3.1e-05 24.1 0.1 0.031 14.3 0.2 2.1 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EGB03854.1 - 0.0003 20.7 0.6 0.0013 18.6 0.6 1.8 1 1 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGB03854.1 - 0.0056 17.2 0.1 0.011 16.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 EGB03854.1 - 0.0066 16.0 0.0 0.008 15.7 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 EGB03854.1 - 0.026 14.8 0.1 0.041 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB03854.1 - 0.091 13.1 2.2 0.092 13.1 0.5 1.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGB03854.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EGB03854.1 - 0.16 12.2 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Exostosin PF03016.15 EGB03855.1 - 0.00087 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Myosin_head PF00063.21 EGB03856.1 - 2.5e-186 620.9 0.0 2.9e-186 620.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EGB03856.1 - 0.00041 20.1 0.0 0.00088 19.1 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 EGB03856.1 - 0.0025 18.2 0.1 0.0078 16.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGB03856.1 - 0.0092 15.3 0.1 0.27 10.5 0.1 2.6 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.6 EGB03856.1 - 0.018 15.3 0.1 0.05 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGB03857.1 - 1.6e-17 64.1 0.0 2.9e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EGB03857.1 - 1.6e-12 47.4 1.7 1.6e-12 47.4 1.7 2.0 2 0 0 2 2 2 1 AAA lid domain AAA_22 PF13401.6 EGB03857.1 - 1.3e-05 25.5 0.9 0.014 15.7 0.1 3.1 2 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EGB03857.1 - 1.5e-05 24.8 0.1 3.7e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EGB03857.1 - 4.2e-05 23.0 0.2 0.0043 16.5 0.1 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGB03857.1 - 0.00015 22.2 4.7 0.0032 17.9 4.7 2.5 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EGB03857.1 - 0.0013 17.9 0.3 0.47 9.6 0.1 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_19 PF13245.6 EGB03857.1 - 0.0016 18.8 0.2 0.0028 18.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB03857.1 - 0.0092 16.1 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB03857.1 - 0.014 15.1 5.8 0.021 14.5 3.7 2.4 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EGB03857.1 - 0.017 15.1 0.5 0.048 13.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGB03857.1 - 0.031 14.0 0.1 2.4 7.8 0.1 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Torsin PF06309.11 EGB03857.1 - 0.056 13.5 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Torsin RNA_helicase PF00910.22 EGB03857.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EGB03857.1 - 0.085 12.6 0.1 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA_pol_N PF01194.17 EGB03858.1 - 4.7e-34 116.5 0.4 5.9e-34 116.2 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit YhfH PF14149.6 EGB03858.1 - 0.048 13.6 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 YhfH-like protein F-box-like PF12937.7 EGB03859.1 - 1.8e-06 27.7 0.0 4.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGB03859.1 - 0.0067 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain AAA PF00004.29 EGB03860.1 - 1.1e-28 100.3 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB03860.1 - 6.1e-08 33.2 0.1 4.7e-06 27.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGB03860.1 - 5.8e-06 26.1 0.1 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB03860.1 - 1.9e-05 25.0 0.0 0.0036 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGB03860.1 - 4.4e-05 23.5 0.1 0.00078 19.5 0.1 2.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGB03860.1 - 0.00017 21.3 0.1 0.00027 20.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB03860.1 - 0.0028 17.3 0.9 0.21 11.1 0.3 2.5 1 1 2 3 3 3 1 AAA domain Zot PF05707.12 EGB03860.1 - 0.0032 17.2 0.0 0.013 15.2 0.0 1.8 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) NACHT PF05729.12 EGB03860.1 - 0.0033 17.4 0.0 0.031 14.2 0.0 2.1 1 1 1 2 2 2 1 NACHT domain AFG1_ATPase PF03969.16 EGB03860.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase IstB_IS21 PF01695.17 EGB03860.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EGB03860.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB03860.1 - 0.013 14.8 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGB03860.1 - 0.017 15.5 0.0 0.32 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 EGB03860.1 - 0.022 13.9 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EGB03860.1 - 0.038 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGB03860.1 - 0.041 13.9 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 EGB03860.1 - 0.049 12.7 0.0 0.099 11.7 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 EGB03860.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 EGB03860.1 - 0.061 13.2 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGB03860.1 - 0.075 12.4 0.0 0.51 9.7 0.0 2.1 2 1 1 3 3 3 0 Bacterial TniB protein NB-ARC PF00931.22 EGB03860.1 - 0.076 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 EGB03860.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EGB03860.1 - 0.12 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB03860.1 - 0.14 12.6 0.0 0.25 11.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EGB03860.1 - 0.15 12.6 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGB03860.1 - 0.16 11.9 0.1 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_2 PF07724.14 EGB03860.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 EGB03860.1 - 0.18 12.1 0.2 0.76 10.1 0.2 1.8 1 1 1 2 2 2 0 AAA domain AAA_lid_3 PF17862.1 EGB03860.1 - 0.92 9.4 4.6 0.21 11.4 0.5 2.2 2 0 0 2 2 1 0 AAA+ lid domain Ion_trans PF00520.31 EGB03861.1 - 2.3e-08 33.6 1.1 3e-08 33.2 1.1 1.1 1 0 0 1 1 1 1 Ion transport protein HAT_KAT11 PF08214.11 EGB03862.1 - 6.4e-26 91.4 0.0 1.9e-25 89.9 0.0 1.6 1 1 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 EGB03862.1 - 1.1e-17 63.9 0.0 2.1e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.17 EGB03862.1 - 3.1e-08 33.3 7.9 6.9e-08 32.2 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Rubredoxin_2 PF18073.1 EGB03862.1 - 4.7 7.0 10.4 0.084 12.6 1.9 2.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain Sel1 PF08238.12 EGB03863.1 - 1.5e-10 41.4 9.9 0.0053 17.4 0.1 5.0 5 0 0 5 5 5 4 Sel1 repeat Methyltransf_11 PF08241.12 EGB03864.1 - 4.7e-14 52.8 0.0 8.4e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03864.1 - 1.4e-13 51.4 0.0 3.3e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 EGB03864.1 - 7.4e-13 49.1 10.0 7.4e-13 49.1 10.0 1.7 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_12 PF08242.12 EGB03864.1 - 3.2e-08 34.2 0.0 5.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB03864.1 - 8.8e-05 21.9 0.0 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EGB03864.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03864.1 - 0.00027 20.8 0.0 0.00039 20.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB03864.1 - 0.0003 20.2 0.0 0.00046 19.6 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGB03864.1 - 0.00067 19.5 0.0 0.00095 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.18 EGB03864.1 - 0.0019 18.0 0.0 0.029 14.1 0.0 2.2 2 1 0 2 2 2 1 DNA methylase PrmA PF06325.13 EGB03864.1 - 0.0032 16.9 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB03864.1 - 0.011 15.3 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AdoMet_MTase PF07757.13 EGB03864.1 - 0.19 12.1 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Castor_Poll_mid PF06241.12 EGB03865.1 - 2.6e-25 88.4 0.0 1.2e-23 83.0 0.0 2.4 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 EGB03865.1 - 0.14 12.0 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 TrkA-C domain Sel1 PF08238.12 EGB03866.1 - 1.1e-49 165.8 34.3 2e-08 34.7 0.2 9.3 9 0 0 9 9 9 8 Sel1 repeat DUF3881 PF12997.7 EGB03866.1 - 0.015 14.5 0.2 4.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF410 PF04190.13 EGB03866.1 - 0.064 13.0 0.8 9.2 6.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_12 PF13424.6 EGB03866.1 - 0.088 13.1 22.2 0.56 10.5 1.4 6.3 5 3 1 6 6 6 0 Tetratricopeptide repeat AAA_lid_10 PF17872.1 EGB03866.1 - 0.36 11.0 1.4 8.3 6.6 0.0 2.8 2 1 1 3 3 3 0 AAA lid domain MIT PF04212.18 EGB03866.1 - 0.64 10.1 14.7 1.5 8.9 0.6 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain B12-binding_2 PF02607.17 EGB03866.1 - 1.3 9.5 7.8 63 4.1 0.0 4.6 5 1 0 5 5 5 0 B12 binding domain TPR_8 PF13181.6 EGB03866.1 - 4.5 7.7 15.8 3.1 8.3 0.2 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB03866.1 - 9.6 7.0 38.4 5.6 7.7 0.1 6.8 5 2 1 7 7 7 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.21 EGB03867.1 - 6.6e-23 81.7 0.1 7.6e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 Acyl transferase domain DUF4085 PF13315.6 EGB03867.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Abhydrolase_6 PF12697.7 EGB03868.1 - 4e-11 44.0 2.6 5.3e-11 43.5 2.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB03868.1 - 3.6e-09 36.2 0.0 0.00017 20.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB03868.1 - 0.0018 18.0 0.0 0.056 13.1 0.1 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB03868.1 - 0.026 14.0 0.1 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family YadA_anchor PF03895.15 EGB03868.1 - 0.03 14.4 0.0 0.086 13.0 0.0 1.7 1 0 0 1 1 1 0 YadA-like membrane anchor domain Abhydrolase_3 PF07859.13 EGB03868.1 - 0.052 13.4 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGB03868.1 - 0.076 12.8 0.0 3.4 7.4 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase family RepB PF07506.11 EGB03868.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein UPF0227 PF05728.12 EGB03868.1 - 0.25 11.3 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) TTL PF03133.15 EGB03869.1 - 1.2e-95 320.1 0.0 1.5e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB03869.1 - 5e-07 29.2 0.0 0.00054 19.3 0.0 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGB03869.1 - 3.1e-05 23.4 0.0 0.083 12.1 0.0 3.0 2 1 0 3 3 3 2 Sugar-transfer associated ATP-grasp zf-RING_2 PF13639.6 EGB03873.1 - 1.8e-07 31.3 1.6 1.8e-07 31.3 1.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGB03873.1 - 2.4e-06 27.3 1.4 4.7e-06 26.4 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB03873.1 - 4.7e-06 26.5 2.5 9.7e-06 25.4 2.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGB03873.1 - 2.2e-05 24.2 2.2 4.2e-05 23.3 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGB03873.1 - 5.7e-05 22.8 3.3 0.00011 21.9 3.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGB03873.1 - 0.00024 20.9 0.8 0.00024 20.9 0.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGB03873.1 - 0.0046 17.0 0.2 0.01 15.9 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGB03873.1 - 0.0088 16.0 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGB03873.1 - 0.026 14.3 1.8 0.055 13.3 1.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGB03873.1 - 0.035 14.4 6.0 0.049 13.9 3.9 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EGB03873.1 - 0.21 11.2 5.5 0.17 11.5 3.2 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EGB03873.1 - 0.22 11.4 2.4 7.7 6.5 1.5 2.3 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 EGB03873.1 - 0.95 9.6 3.0 2.2 8.5 0.8 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger DnaJ PF00226.31 EGB03875.1 - 4e-17 62.1 0.4 4.6e-17 61.9 0.4 1.0 1 0 0 1 1 1 1 DnaJ domain PP2C PF00481.21 EGB03876.1 - 5.3e-40 137.7 0.0 6.1e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB03876.1 - 2.9e-07 30.3 0.0 5.8e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C DUF5578 PF17741.1 EGB03877.1 - 2.8e-20 72.9 0.0 4.6e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Arm PF00514.23 EGB03877.1 - 1 9.5 3.2 7 6.8 0.0 3.7 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4165 PF13752.6 EGB03878.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) DHDPS PF00701.22 EGB03879.1 - 6.9e-82 274.4 0.0 7.9e-82 274.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Inositol_P PF00459.25 EGB03880.1 - 2.6e-41 142.0 0.1 2.8e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Arm PF00514.23 EGB03881.1 - 5.8e-57 188.1 27.0 3.7e-09 36.3 0.1 10.6 10 2 0 10 10 10 8 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EGB03881.1 - 3.2e-09 36.6 0.0 0.0047 16.4 0.0 4.0 1 1 1 2 2 2 2 Armadillo-like HEAT_EZ PF13513.6 EGB03881.1 - 7.9e-07 29.5 30.7 0.02 15.4 1.4 7.6 4 2 5 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 EGB03881.1 - 5e-06 26.8 25.0 0.0038 17.6 3.9 4.8 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.22 EGB03881.1 - 0.00018 21.5 8.7 0.23 11.8 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat KAP PF05804.12 EGB03881.1 - 0.00044 18.6 0.0 1 7.4 0.0 3.0 2 1 1 3 3 3 2 Kinesin-associated protein (KAP) RICTOR_N PF14664.6 EGB03881.1 - 0.0034 16.4 0.0 0.11 11.5 0.0 2.5 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Cnd1 PF12717.7 EGB03881.1 - 0.1 12.6 0.0 12 5.8 0.0 3.0 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Patched PF02460.18 EGB03882.1 - 1.9e-67 228.0 0.0 3.1e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EGB03882.1 - 8.7e-32 110.1 20.8 5.2e-30 104.3 10.9 3.1 2 1 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 EGB03882.1 - 4.9e-06 24.5 1.2 7.8e-06 23.9 1.2 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EGB03882.1 - 0.00019 20.5 23.0 0.0031 16.5 1.2 3.4 3 0 0 3 3 3 2 MMPL family DUF883 PF05957.13 EGB03882.1 - 0.014 16.0 1.0 0.64 10.7 0.1 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Wzy_C PF04932.15 EGB03882.1 - 3.8 7.1 7.7 2.9 7.5 1.1 3.0 2 0 0 2 2 2 0 O-Antigen ligase Steroid_dh PF02544.16 EGB03883.1 - 8.1e-19 68.1 0.0 1.5e-16 60.8 0.0 2.3 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase PUB PF09409.10 EGB03884.1 - 6.7e-12 45.2 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 PUB domain Glyco_transf_90 PF05686.12 EGB03884.1 - 4.2e-06 25.9 0.0 6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 PFU PF09070.11 EGB03884.1 - 1.2e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGB03884.1 - 0.00031 21.5 12.5 0.13 13.2 0.0 5.8 7 0 0 7 7 7 2 WD domain, G-beta repeat UBA PF00627.31 EGB03884.1 - 0.0033 17.3 0.3 0.01 15.7 0.3 2.0 1 0 0 1 1 1 1 UBA/TS-N domain PQQ_3 PF13570.6 EGB03884.1 - 0.28 11.7 12.5 3.9 8.1 0.2 5.7 4 1 0 4 4 4 0 PQQ-like domain DegT_DnrJ_EryC1 PF01041.17 EGB03885.1 - 2.9e-50 171.6 0.0 3.9e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Acyl-CoA_dh_1 PF00441.24 EGB03886.1 - 1.9e-35 122.3 4.9 3.5e-35 121.4 4.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGB03886.1 - 2.1e-30 105.7 0.1 6.1e-30 104.2 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGB03886.1 - 1.2e-20 73.4 0.0 2.8e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGB03886.1 - 4.3e-18 65.9 4.0 4.3e-18 65.9 4.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pro_isomerase PF00160.21 EGB03887.1 - 2e-46 158.2 0.8 2.3e-46 158.0 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DSPc PF00782.20 EGB03888.1 - 1.3e-20 73.5 0.0 1.4e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB03888.1 - 0.00054 19.6 0.1 0.00057 19.5 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGB03888.1 - 0.14 11.8 0.2 0.17 11.5 0.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pkinase PF00069.25 EGB03889.1 - 3.7e-54 183.9 0.0 9.8e-54 182.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03889.1 - 3.4e-26 92.1 0.0 4.5e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB03889.1 - 8.4e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB03889.1 - 0.034 13.5 0.0 0.15 11.4 0.0 2.0 3 1 0 3 3 3 0 Kinase-like EcKinase PF02958.20 EGB03889.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pro-rich PF15240.6 EGB03890.1 - 0.007 16.7 2.7 0.016 15.5 2.6 1.8 1 1 0 1 1 1 1 Proline-rich WD40 PF00400.32 EGB03891.1 - 4e-16 59.1 12.7 0.0089 16.9 0.1 8.5 8 1 1 9 9 9 5 WD domain, G-beta repeat HELP PF03451.14 EGB03891.1 - 3.2e-14 52.5 0.0 6.3e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 EGB03891.1 - 4.1e-06 27.0 0.1 0.012 15.9 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1983 PF09327.11 EGB03891.1 - 0.095 12.8 0.8 0.24 11.5 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1983) eIF2A PF08662.11 EGB03891.1 - 0.11 12.4 0.1 0.55 10.1 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PALP PF00291.25 EGB03892.1 - 1.4e-59 201.9 0.8 1.6e-59 201.7 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ion_trans_2 PF07885.16 EGB03894.1 - 3.6e-21 74.9 6.2 2.1e-10 40.4 0.6 2.4 2 0 0 2 2 2 2 Ion channel Mito_carr PF00153.27 EGB03894.1 - 5.1e-16 58.4 0.7 0.00034 20.5 0.0 4.7 4 1 0 4 4 4 3 Mitochondrial carrier protein Methyltransf_11 PF08241.12 EGB03894.1 - 1.6e-07 31.9 0.0 3.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB03894.1 - 8.3e-05 23.2 0.0 0.00024 21.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB03894.1 - 0.0018 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB03894.1 - 0.099 13.4 0.0 0.29 11.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Ion_trans PF00520.31 EGB03894.1 - 0.27 10.5 0.0 18 4.4 0.0 2.1 2 0 0 2 2 2 0 Ion transport protein CRAL_TRIO PF00650.20 EGB03895.1 - 3.3e-16 59.4 0.0 4.1e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Mito_carr PF00153.27 EGB03897.1 - 2e-37 127.0 0.7 1.3e-11 44.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4804 PF16062.5 EGB03897.1 - 0.34 9.7 0.2 0.49 9.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) Pkinase PF00069.25 EGB03899.1 - 2.1e-53 181.4 0.0 2.5e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03899.1 - 2e-23 83.0 0.0 2.5e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB03899.1 - 0.0017 17.8 0.0 0.0036 16.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Eno-Rase_NADH_b PF12242.8 EGB03899.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ABC_membrane PF00664.23 EGB03900.1 - 4.9e-23 82.2 0.3 5.9e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB03900.1 - 2e-21 77.0 0.0 3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGB03900.1 - 0.0036 17.0 0.1 0.0079 15.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EGB03900.1 - 0.014 15.2 5.4 0.092 12.4 5.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB03900.1 - 0.022 14.9 0.0 0.4 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGB03900.1 - 0.022 15.1 4.4 0.023 15.1 1.9 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EGB03900.1 - 0.022 14.6 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB03900.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGB03900.1 - 0.12 12.9 0.0 0.87 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB03900.1 - 0.27 10.6 2.4 0.3 10.4 0.4 2.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.32 EGB03901.1 - 1.5e-05 25.6 0.5 0.0079 17.0 0.0 4.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Allexi_40kDa PF05549.11 EGB03901.1 - 0.14 11.7 1.1 0.34 10.4 0.1 2.0 2 1 0 2 2 2 0 Allexivirus 40kDa protein ANAPC4_WD40 PF12894.7 EGB03901.1 - 0.17 12.2 0.0 1.5 9.2 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ARL2_Bind_BART PF11527.8 EGB03902.1 - 1.4e-22 80.0 0.1 1.8e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART ATP-synt_DE PF00401.20 EGB03902.1 - 0.068 13.4 0.7 1.1 9.6 0.4 2.4 1 1 1 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Ammonium_transp PF00909.21 EGB03903.1 - 3.4e-92 309.2 34.5 4.2e-92 308.9 34.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM107 PF14995.6 EGB03904.1 - 1.2e-40 138.8 2.3 1.5e-40 138.5 2.3 1.1 1 0 0 1 1 1 1 Transmembrane protein Cullin_binding PF03556.15 EGB03906.1 - 1.1e-19 71.0 0.1 1.4e-19 70.7 0.1 1.1 1 0 0 1 1 1 1 Cullin binding Sulfotransfer_1 PF00685.27 EGB03908.1 - 0.0012 18.4 0.0 0.26 10.7 0.0 2.3 2 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB03908.1 - 0.017 15.5 0.1 0.38 11.1 0.1 2.3 1 1 0 1 1 1 0 Sulfotransferase family CRAL_TRIO PF00650.20 EGB03909.1 - 1.1e-12 47.9 0.0 1.6e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Glycos_transf_2 PF00535.26 EGB03910.1 - 1.8e-07 31.1 0.0 4.9e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB03910.1 - 8e-05 22.6 0.1 0.00016 21.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MFS_1 PF07690.16 EGB03912.1 - 1.7e-27 96.3 39.4 1.6e-23 83.2 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB03912.1 - 1.7e-24 86.5 6.1 1.7e-20 73.3 0.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter 2OG-FeII_Oxy_3 PF13640.6 EGB03912.1 - 2.8e-17 63.4 0.0 5.2e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB03912.1 - 3.4e-09 37.3 0.0 5.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB03912.1 - 0.0008 19.9 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OTU PF02338.19 EGB03913.1 - 0.11 13.0 0.1 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 OTU-like cysteine protease LBP_BPI_CETP_C PF02886.17 EGB03914.1 - 1.3e-08 34.6 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Thioredoxin_4 PF13462.6 EGB03914.1 - 0.0026 17.9 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EGB03914.1 - 0.01 15.6 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain LBP_BPI_CETP PF01273.25 EGB03914.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain ArfGap PF01412.18 EGB03916.1 - 2.3e-22 79.2 1.1 2.4e-22 79.2 1.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Rubredoxin_2 PF18073.1 EGB03916.1 - 0.016 14.9 1.4 0.86 9.4 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain LRR_8 PF13855.6 EGB03917.1 - 4e-16 58.5 10.8 8.3e-08 31.9 0.2 2.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGB03917.1 - 5e-12 45.8 2.1 6.5e-05 23.2 0.0 3.8 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB03917.1 - 2.9e-05 24.0 2.9 8.1 7.4 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 EGB03917.1 - 7.4 6.9 7.9 60 4.1 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Big_9 PF17963.1 EGB03918.1 - 0.0035 18.0 95.5 0.054 14.3 1.4 21.8 19 7 0 19 19 19 5 Bacterial Ig domain Cadherin_5 PF17892.1 EGB03918.1 - 0.15 12.1 17.7 68 3.5 0.0 9.3 11 0 0 11 11 11 0 Cadherin-like domain PseudoU_synth_2 PF00849.22 EGB03919.1 - 2.3e-24 86.3 0.0 2.9e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Sel1 PF08238.12 EGB03920.1 - 9.6e-35 118.3 7.5 5.6e-07 30.0 0.1 5.4 5 0 0 5 5 5 5 Sel1 repeat MIT PF04212.18 EGB03920.1 - 0.0012 18.9 3.7 0.014 15.5 0.3 3.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Fer2_3 PF13085.6 EGB03920.1 - 0.021 14.9 0.5 0.043 13.8 0.5 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TPR_16 PF13432.6 EGB03920.1 - 0.024 15.3 11.2 3.7 8.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 EGB03920.1 - 0.029 14.2 10.0 0.051 13.4 10.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HEAT PF02985.22 EGB03921.1 - 0.084 13.2 9.9 1.8 9.0 0.3 4.7 4 0 0 4 4 4 0 HEAT repeat VASt PF16016.5 EGB03923.1 - 0.039 14.3 0.0 0.048 14.1 0.0 1.1 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain DHHC PF01529.20 EGB03924.1 - 2.8e-13 50.2 9.9 3e-13 50.0 9.9 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase zf-tcix PF14952.6 EGB03924.1 - 0.053 13.1 5.2 0.07 12.7 5.2 1.4 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Rdx PF10262.9 EGB03925.1 - 2.6e-12 46.8 0.0 7.8e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 Rdx family Ribonuc_red_lgC PF02867.15 EGB03926.1 - 7.7e-23 80.8 0.0 8.3e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgC PF02867.15 EGB03927.1 - 6e-65 219.8 0.0 6.6e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain ABC_membrane_2 PF06472.15 EGB03928.1 - 1.3e-19 70.7 0.0 1.7e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGB03928.1 - 1.6e-18 67.5 0.0 3.3e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB03928.1 - 1.6e-05 25.4 1.4 2.6e-05 24.7 0.5 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EGB03928.1 - 0.0002 21.1 0.0 0.00054 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain SbmA_BacA PF05992.12 EGB03928.1 - 0.00031 20.3 0.1 0.00043 19.8 0.1 1.2 1 0 0 1 1 1 1 SbmA/BacA-like family ArsP_2 PF11449.8 EGB03928.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter NACHT PF05729.12 EGB03928.1 - 0.019 14.9 0.1 0.039 13.9 0.1 1.7 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 EGB03928.1 - 0.049 14.1 0.1 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGB03928.1 - 0.056 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_membrane PF00664.23 EGB03928.1 - 0.063 12.9 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region T2SSE PF00437.20 EGB03928.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EGB03928.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EGB03928.1 - 0.069 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB03928.1 - 0.13 12.0 0.1 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system IL6 PF00489.17 EGB03928.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family AAA_7 PF12775.7 EGB03928.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGB03928.1 - 0.16 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Tubulin PF00091.25 EGB03929.1 - 3.6e-63 213.3 0.0 5e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB03929.1 - 2.4e-49 166.7 0.0 3.5e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain GlcNAc_2-epim PF07221.11 EGB03930.1 - 1.3e-91 307.4 9.6 1.7e-91 307.1 9.6 1.0 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) C5-epim_C PF06662.13 EGB03930.1 - 0.0056 16.2 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Chloroa_b-bind PF00504.21 EGB03931.1 - 1.5e-25 90.6 0.0 1.9e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Myb_DNA-binding PF00249.31 EGB03932.1 - 3.8e-16 59.0 0.2 5.7e-07 29.6 0.4 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB03932.1 - 2.2e-14 53.4 0.1 3.2e-10 40.1 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EGB03932.1 - 0.0068 16.5 0.4 0.013 15.5 0.3 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGB03932.1 - 0.062 13.7 0.2 0.15 12.5 0.1 1.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EGB03933.1 - 3.6e-22 79.0 0.0 4e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03933.1 - 2.9e-09 36.6 0.0 3.3e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB03933.1 - 0.18 11.1 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like ATP11 PF06644.11 EGB03934.1 - 3.2e-24 86.2 0.0 3.5e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Aminotran_1_2 PF00155.21 EGB03935.1 - 3e-25 89.2 0.0 2.9e-24 85.9 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II EF-hand_6 PF13405.6 EGB03935.1 - 0.0026 17.6 0.0 0.061 13.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EGB03935.1 - 0.0033 16.8 0.1 0.0077 15.7 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 EGB03935.1 - 0.012 15.1 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 EF hand Kinesin PF00225.23 EGB03936.1 - 4.2e-104 348.1 0.8 5.3e-104 347.7 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGB03936.1 - 8e-48 162.2 0.0 1.4e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding MRP-S31 PF15433.6 EGB03936.1 - 0.0067 16.1 3.5 0.011 15.5 3.5 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 TMEM247 PF15444.6 EGB03936.1 - 0.075 13.1 2.7 0.17 11.9 2.7 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 FadA PF09403.10 EGB03936.1 - 0.2 12.1 8.7 0.42 11.1 7.9 2.1 1 1 0 1 1 1 0 Adhesion protein FadA LMBR1 PF04791.16 EGB03936.1 - 0.68 8.8 2.4 0.89 8.4 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 EGB03936.1 - 2.7 7.2 4.2 6.2 6.0 3.9 1.7 1 1 0 1 1 1 0 TMPIT-like protein Cdh1_DBD_1 PF18196.1 EGB03936.1 - 4.5 7.6 9.3 16 5.8 9.3 2.0 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 GCN5L1 PF06320.13 EGB03936.1 - 4.5 7.4 8.4 8.9 6.5 2.1 3.4 3 1 1 4 4 4 0 GCN5-like protein 1 (GCN5L1) FUSC PF04632.12 EGB03936.1 - 4.9 5.6 7.4 8.3 4.8 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EGB03936.1 - 5 6.4 9.9 9.4 5.5 9.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ISG65-75 PF11727.8 EGB03936.1 - 5.3 6.2 10.4 11 5.2 10.4 1.6 1 0 0 1 1 1 0 Invariant surface glycoprotein OmpH PF03938.14 EGB03936.1 - 6.1 7.2 13.4 15 5.9 12.7 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 EGB03936.1 - 7.5 5.3 9.9 12 4.6 9.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein YlqD PF11068.8 EGB03936.1 - 8.5 6.8 7.7 5.5 7.4 0.5 2.3 1 1 1 2 2 2 0 YlqD protein COG2 PF06148.11 EGB03936.1 - 9.1 6.4 6.9 21 5.2 0.3 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.8 EGB03936.1 - 9.4 6.3 12.6 7.7 6.6 4.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ribul_P_3_epim PF00834.19 EGB03938.1 - 7.8e-88 293.0 0.0 9.4e-88 292.8 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EGB03938.1 - 8e-06 25.7 0.0 0.00033 20.5 0.0 2.2 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EGB03938.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF4516 PF14990.6 EGB03938.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DnaJ PF00226.31 EGB03939.1 - 2.3e-20 72.5 0.2 2.7e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 DnaJ domain Torsin PF06309.11 EGB03940.1 - 7.2e-05 22.9 0.1 0.00031 20.8 0.0 2.0 3 0 0 3 3 3 1 Torsin AAA_16 PF13191.6 EGB03940.1 - 0.00039 20.8 2.2 0.0091 16.4 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGB03940.1 - 0.08 13.2 0.1 3.5 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGB03940.1 - 0.19 11.7 0.1 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Kelch_1 PF01344.25 EGB03941.1 - 7.6e-05 22.2 2.1 0.005 16.4 0.2 3.1 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 EGB03941.1 - 0.00061 19.7 0.4 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 Kelch motif SH3_12 PF18129.1 EGB03941.1 - 0.0015 18.6 10.8 1.9 8.7 0.1 4.7 4 0 0 4 4 4 2 Xrn1 SH3-like domain TUDOR_5 PF18359.1 EGB03941.1 - 0.0044 16.7 0.3 0.061 13.0 0.0 2.5 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 Kelch_6 PF13964.6 EGB03941.1 - 0.0054 17.0 0.6 0.99 9.8 0.1 2.7 1 1 1 2 2 2 1 Kelch motif Kelch_5 PF13854.6 EGB03941.1 - 0.0054 16.7 0.3 0.015 15.3 0.3 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 EGB03941.1 - 0.0078 16.2 0.5 4.2 7.4 0.1 3.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Podoplanin PF05808.11 EGB03941.1 - 0.013 15.6 0.9 0.013 15.6 0.9 2.2 2 1 1 3 3 2 0 Podoplanin TMEM154 PF15102.6 EGB03941.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Cul7 PF11515.8 EGB03941.1 - 0.083 13.2 0.7 26 5.2 0.0 3.3 3 0 0 3 3 3 0 Mouse development and cellular proliferation protein Cullin-7 Kelch_3 PF13415.6 EGB03941.1 - 0.087 13.1 0.0 2.1 8.7 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain VSP PF03302.13 EGB03941.1 - 0.25 10.2 0.2 0.4 9.5 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein AMP-binding PF00501.28 EGB03942.1 - 1.8e-61 208.0 0.0 2.3e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB03942.1 - 0.13 13.3 0.2 0.23 12.5 0.2 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 EGB03943.1 - 8.3e-37 127.1 8.1 8.3e-37 127.1 8.1 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB03943.1 - 7.9e-07 29.1 0.1 1.9e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB03943.1 - 0.0024 17.3 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGB03943.1 - 0.032 14.1 2.5 0.21 11.5 0.2 2.7 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III OTCace PF00185.24 EGB03944.1 - 2.5e-48 164.1 0.0 3.6e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EGB03944.1 - 3.7e-38 130.9 0.0 6.4e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Ribosomal_S16 PF00886.19 EGB03945.1 - 4.3e-28 97.1 0.1 5.2e-28 96.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Ank_2 PF12796.7 EGB03946.1 - 3.5e-06 27.5 0.0 7.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB03946.1 - 2.3e-05 24.6 0.1 0.004 17.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB03946.1 - 0.00082 19.9 0.0 0.0037 17.8 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB03946.1 - 0.057 14.0 0.0 0.3 11.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 EGB03946.1 - 0.13 12.8 0.0 1.3 9.5 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Methyltransf_23 PF13489.6 EGB03947.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0146 PF03686.13 EGB03947.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) FtsJ PF01728.19 EGB03947.1 - 0.057 13.5 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MORN PF02493.20 EGB03948.1 - 2.2e-46 153.0 46.4 0.00021 21.0 0.1 13.2 13 0 0 13 13 13 11 MORN repeat Beta_helix PF13229.6 EGB03948.1 - 0.0018 18.1 1.1 0.6 10.0 0.1 2.3 1 1 1 2 2 2 2 Right handed beta helix region NHL PF01436.21 EGB03948.1 - 0.045 13.8 2.0 20 5.4 0.0 3.8 3 0 0 3 3 3 0 NHL repeat 2OG-FeII_Oxy_5 PF13759.6 EGB03949.1 - 3.8e-13 49.7 0.0 6.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DHQ_synthase PF01761.20 EGB03950.1 - 1.3e-59 201.6 0.0 1.8e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EGB03950.1 - 3.3e-05 23.7 0.0 5.7e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EGB03950.1 - 0.038 12.8 0.1 0.24 10.2 0.1 2.0 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase GDP_Man_Dehyd PF16363.5 EGB03951.1 - 2.6e-154 513.5 0.0 3e-154 513.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGB03951.1 - 1.9e-72 243.6 0.1 2.4e-72 243.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGB03951.1 - 7.4e-06 25.3 0.0 1.5e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGB03951.1 - 2.9e-05 23.4 0.0 4.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EGB03951.1 - 0.029 13.9 0.0 0.078 12.5 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family TAA-Trp-ring PF15401.6 EGB03951.1 - 0.047 14.2 0.1 0.1 13.1 0.1 1.6 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin CheR PF01739.18 EGB03952.1 - 1.2e-22 80.3 0.0 2.9e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain PhyH PF05721.13 EGB03953.1 - 1.9e-14 54.4 0.8 3.2e-14 53.7 0.8 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sulphotransf PF09037.10 EGB03953.1 - 1.5e-06 27.9 0.0 4.8e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Stf0 sulphotransferase Sulfotransfer_3 PF13469.6 EGB03953.1 - 0.048 14.0 0.0 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Glyco_trans_1_4 PF13692.6 EGB03954.1 - 1.7e-07 31.8 0.0 3.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB03954.1 - 8.8e-05 22.1 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Chloroa_b-bind PF00504.21 EGB03955.1 - 1.4e-30 107.0 0.6 2.1e-30 106.4 0.6 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein MBOAT PF03062.19 EGB03957.1 - 3.8e-29 102.1 12.9 5.3e-29 101.7 12.9 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGB03957.1 - 0.011 16.0 3.0 0.021 15.1 2.5 1.7 1 1 0 1 1 1 0 Membrane bound O-acyl transferase family Aldedh PF00171.22 EGB03958.1 - 1.9e-157 524.5 0.0 2.1e-157 524.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGB03958.1 - 0.16 11.4 0.1 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SPOR PF05036.13 EGB03959.1 - 0.032 14.6 0.3 0.032 14.6 0.3 2.6 3 0 0 3 3 3 0 Sporulation related domain Tyrosinase PF00264.20 EGB03960.1 - 1.1e-08 35.6 0.0 0.00074 19.9 0.0 2.2 2 0 0 2 2 2 2 Common central domain of tyrosinase zf-C3HC4_3 PF13920.6 EGB03961.1 - 9.9e-10 38.1 6.5 9.9e-10 38.1 6.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.6 EGB03961.1 - 2.1e-09 37.1 0.1 5.1e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Prok-RING_4 PF14447.6 EGB03961.1 - 2.5e-08 33.6 7.1 2.5e-08 33.6 7.1 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGB03961.1 - 2.1e-07 30.7 5.3 2.1e-07 30.7 5.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB03961.1 - 9.2e-07 29.1 5.7 9.2e-07 29.1 5.7 2.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB03961.1 - 1.1e-06 28.4 6.2 1.1e-06 28.4 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HELP PF03451.14 EGB03961.1 - 7.2e-06 25.8 0.1 1.7e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 HELP motif zf-RING_5 PF14634.6 EGB03961.1 - 2.7e-05 24.0 5.0 2.7e-05 24.0 5.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB03961.1 - 0.00024 21.0 2.0 0.00032 20.7 0.3 2.1 2 1 0 2 2 2 1 RING-type zinc-finger SH3_2 PF07653.17 EGB03961.1 - 0.00031 20.4 0.0 0.00072 19.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB03961.1 - 0.0017 17.9 0.1 0.0052 16.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain zf-C2HC_2 PF13913.6 EGB03961.1 - 0.019 14.9 4.6 0.056 13.4 4.6 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type SBP PF03110.14 EGB03961.1 - 0.022 15.1 0.1 0.022 15.1 0.1 2.2 2 0 0 2 2 2 0 SBP domain zf-C3HC4_4 PF15227.6 EGB03961.1 - 0.088 13.0 6.0 0.24 11.6 6.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING WD40 PF00400.32 EGB03961.1 - 7.1 7.7 14.9 77 4.4 0.0 7.2 9 0 0 9 9 7 0 WD domain, G-beta repeat SMC_N PF02463.19 EGB03962.1 - 4.5e-60 202.8 0.0 5.5e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGB03962.1 - 2.9e-23 82.4 1.5 1.4e-22 80.2 0.1 3.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGB03962.1 - 3.2e-17 63.7 0.0 3.2e-17 63.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 EGB03962.1 - 1.8e-11 44.4 0.0 3.7e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGB03962.1 - 9.7e-07 28.8 0.0 4.3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGB03962.1 - 1.3e-06 28.0 0.0 3.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGB03962.1 - 9.1e-05 23.0 0.0 0.58 10.7 0.0 3.5 3 0 0 3 3 3 2 ABC transporter MCD_N PF17408.2 EGB03962.1 - 1.9 8.6 10.6 0.26 11.4 2.5 4.0 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain TPT PF03151.16 EGB03963.1 - 2.1e-89 299.7 9.8 2.4e-89 299.5 9.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB03963.1 - 1.3e-14 54.5 18.2 7.8e-08 32.6 2.6 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGB03963.1 - 0.021 14.0 6.7 0.54 9.4 2.1 2.2 1 1 1 2 2 2 0 UAA transporter family Ribosomal_S6e PF01092.19 EGB03964.1 - 1.5e-57 193.0 0.1 3e-57 192.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Cas_Cas4 PF01930.17 EGB03964.1 - 0.3 11.2 3.6 0.48 10.5 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 TYW3 PF02676.14 EGB03965.1 - 3.4e-36 124.6 0.0 5.4e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.16 EGB03965.1 - 9.2e-15 54.9 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein zf-C3HC4 PF00097.25 EGB03965.1 - 2e-06 27.6 8.3 4.3e-06 26.5 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGB03965.1 - 2.7e-06 27.4 8.0 5.2e-06 26.5 8.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGB03965.1 - 6.4e-06 26.1 4.7 1.6e-05 24.8 4.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGB03965.1 - 4.4e-05 23.3 8.5 9.9e-05 22.1 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB03965.1 - 0.00026 21.2 9.5 0.00077 19.7 9.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB03965.1 - 0.00039 20.2 10.0 0.00068 19.4 9.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB03965.1 - 0.0058 16.6 8.9 0.014 15.4 8.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGB03965.1 - 0.026 14.4 7.9 0.054 13.4 7.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EGB03965.1 - 0.87 9.5 10.1 0.1 12.5 4.6 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGB03965.1 - 0.89 9.4 9.4 0.03 14.1 2.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf_C2HC_14 PF18574.1 EGB03965.1 - 2.9 7.8 8.0 0.045 13.6 0.5 1.9 2 0 0 2 2 2 0 C2HC Zing finger domain Thymidylate_kin PF02223.17 EGB03967.1 - 3.4e-44 150.7 0.0 4e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CobU PF02283.16 EGB03967.1 - 0.045 13.3 0.2 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF1298 PF06974.13 EGB03968.1 - 1.7e-16 60.4 0.0 3.3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 EGB03968.1 - 4.6e-09 36.4 1.8 5.2e-08 33.0 0.6 2.5 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Sel1 PF08238.12 EGB03970.1 - 4.1e-13 49.5 8.9 0.00022 21.8 0.1 5.0 5 1 0 5 5 5 4 Sel1 repeat TPR_16 PF13432.6 EGB03970.1 - 0.073 13.7 15.1 0.27 11.9 3.3 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat zf-C2H2_10 PF16588.5 EGB03970.1 - 7.3 6.4 5.5 34 4.3 0.2 2.3 2 0 0 2 2 2 0 C2H2 zinc-finger Fe-ADH PF00465.19 EGB03972.1 - 6.7e-59 199.5 1.4 7.6e-59 199.4 1.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGB03972.1 - 0.0046 16.7 0.8 0.007 16.1 0.8 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PNK3P PF08645.11 EGB03973.1 - 1.6e-06 27.9 0.0 1.9e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.6 EGB03973.1 - 0.0042 17.2 0.4 0.57 10.3 0.0 2.1 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Cpn60_TCP1 PF00118.24 EGB03974.1 - 9.2e-29 100.4 1.5 1e-28 100.2 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.23 EGB03975.1 - 3.6e-63 213.4 0.1 5.8e-63 212.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB03975.1 - 9.2e-19 67.8 0.0 2.4e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB03975.1 - 1.1e-10 41.8 0.0 2.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB03975.1 - 4.7e-06 26.5 0.0 9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Beta_helix PF13229.6 EGB03975.1 - 9.4e-05 22.3 0.2 0.0002 21.2 0.1 1.5 2 0 0 2 2 2 1 Right handed beta helix region WW PF00397.26 EGB03975.1 - 0.022 14.9 0.2 0.048 13.8 0.2 1.6 1 0 0 1 1 1 0 WW domain F-box PF00646.33 EGB03975.1 - 0.053 13.4 1.9 0.097 12.6 0.4 2.3 2 0 0 2 2 2 0 F-box domain AAA_25 PF13481.6 EGB03975.1 - 0.26 10.8 2.7 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 EGB03975.1 - 3.2 7.7 5.2 0.9 9.5 1.2 2.2 2 0 0 2 2 2 0 F-box-like HECT PF00632.25 EGB03976.1 - 2e-86 290.3 0.0 2.7e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Metallophos PF00149.28 EGB03977.1 - 7.7e-34 118.0 1.2 1e-33 117.6 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGB03977.1 - 0.024 15.1 0.1 0.061 13.8 0.1 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain CBFD_NFYB_HMF PF00808.23 EGB03978.1 - 2.5e-25 88.5 0.2 3.6e-25 88.0 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB03978.1 - 0.00021 21.7 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGB03978.1 - 0.014 15.5 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EGB03978.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit NAD_Gly3P_dh_C PF07479.14 EGB03979.1 - 1.9e-17 63.9 2.2 2.7e-17 63.4 2.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EGB03979.1 - 2.6e-13 50.2 0.0 3.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EGB03979.1 - 0.00031 20.4 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EGB03979.1 - 0.0067 15.7 0.2 0.0087 15.3 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGB03979.1 - 0.051 14.1 0.9 0.16 12.5 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pep_deformylase PF01327.21 EGB03980.1 - 1.4e-41 141.7 0.0 2e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase LPD16 PF18830.1 EGB03980.1 - 0.22 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 16 Pkinase PF00069.25 EGB03981.1 - 6.7e-25 87.9 0.0 1.2e-24 87.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB03981.1 - 0.00022 20.6 0.0 0.00038 19.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Histone_H2A_C PF16211.5 EGB03982.1 - 8.3e-20 70.2 1.4 2e-19 69.0 1.4 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB03982.1 - 5.1e-12 46.3 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB03982.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone WWE PF02825.20 EGB03983.1 - 1.6e-07 31.8 0.0 2.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 WWE domain SAP PF02037.27 EGB03983.1 - 1.4e-05 24.7 0.3 2.1e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 SAP domain PDZ_6 PF17820.1 EGB03984.1 - 3.6e-05 23.5 5.5 0.017 15.0 1.6 2.9 2 0 0 2 2 2 2 PDZ domain SET PF00856.28 EGB03984.1 - 0.00014 22.3 0.0 0.0029 18.0 0.0 3.2 4 1 0 4 4 4 1 SET domain PDZ_2 PF13180.6 EGB03984.1 - 0.0047 17.2 0.4 0.75 10.2 0.1 2.6 2 0 0 2 2 2 1 PDZ domain CUE PF02845.16 EGB03984.1 - 0.077 12.7 0.1 1.6 8.5 0.0 2.8 3 0 0 3 3 3 0 CUE domain PMSR PF01625.21 EGB03985.1 - 1.2e-16 61.3 0.0 2.1e-16 60.5 0.0 1.4 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase NAD_binding_11 PF14833.6 EGB03986.1 - 3.1e-19 69.4 0.5 3.1e-19 69.4 0.5 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EGB03986.1 - 7.2e-15 55.5 0.4 1.1e-14 55.0 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EGB03986.1 - 0.0032 16.8 0.3 0.0065 15.9 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1118 PF06549.12 EGB03986.1 - 7.6 6.9 8.2 1.8 8.9 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1118) Formyl_trans_N PF00551.19 EGB03987.1 - 1.9e-37 128.7 0.0 3.7e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase LytR_C PF13399.6 EGB03987.1 - 0.031 15.2 0.3 0.1 13.6 0.3 1.9 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator PP2C PF00481.21 EGB03988.1 - 3.5e-43 148.1 0.0 4.3e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB03988.1 - 0.0024 17.8 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) WD40 PF00400.32 EGB03989.1 - 3.6e-14 52.9 12.7 3e-05 24.7 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB03989.1 - 1.2e-07 32.0 0.0 0.071 13.4 0.0 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Pyr_redox_2 PF07992.14 EGB03990.1 - 4.8e-54 183.6 6.2 6e-54 183.3 6.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB03990.1 - 1.6e-27 95.9 0.2 3.7e-27 94.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB03990.1 - 8.3e-15 55.1 1.6 3.5e-12 46.7 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB03990.1 - 2.5e-12 46.7 0.0 1.4e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGB03990.1 - 0.00095 18.6 2.5 0.002 17.6 2.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB03990.1 - 0.0012 18.0 10.7 0.022 13.8 2.7 3.1 2 1 1 3 3 3 2 FAD binding domain HI0933_like PF03486.14 EGB03990.1 - 0.0019 17.0 2.5 0.017 13.9 1.0 2.5 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 EGB03990.1 - 0.0019 17.6 0.2 0.36 10.2 0.3 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EGB03990.1 - 0.0065 15.6 2.3 0.013 14.6 2.3 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGB03990.1 - 0.0069 15.7 2.1 0.05 12.9 0.4 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EGB03990.1 - 0.033 14.4 2.3 0.033 14.4 2.3 3.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGB03990.1 - 0.046 12.8 1.4 0.13 11.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EGB03990.1 - 0.13 12.2 0.3 16 5.5 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding ParA PF10609.9 EGB03991.1 - 1.6e-60 204.7 0.2 1.8e-60 204.5 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGB03991.1 - 1.8e-12 47.4 0.0 4.7e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGB03991.1 - 7.5e-10 39.0 0.1 1.7e-07 31.3 0.0 2.0 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 EGB03991.1 - 9.7e-08 31.6 1.0 7.6e-06 25.4 0.1 2.0 2 0 0 2 2 2 2 ATPase MipZ AAA_25 PF13481.6 EGB03991.1 - 2.7e-05 23.8 0.1 4.4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EGB03991.1 - 0.0014 17.9 2.8 0.01 15.1 0.8 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EGB03991.1 - 0.0041 16.6 0.2 0.012 15.1 0.2 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EGB03991.1 - 0.0056 16.1 0.0 0.064 12.7 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 EGB03991.1 - 0.0061 15.9 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 VirC1 protein SIS_2 PF13580.6 EGB03991.1 - 0.099 12.7 0.5 0.79 9.7 0.1 2.4 2 1 0 2 2 2 0 SIS domain Cu-oxidase_2 PF07731.14 EGB03992.1 - 1.1e-08 35.0 0.2 3.2e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase RuvX PF03652.15 EGB03993.1 - 2.5e-09 37.6 0.0 5.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction resolvase DnaJ_CXXCXGXG PF00684.19 EGB03993.1 - 0.00033 20.9 0.8 0.00033 20.9 0.8 1.7 2 0 0 2 2 2 1 DnaJ central domain TPR_2 PF07719.17 EGB03993.1 - 0.0012 18.8 0.9 0.13 12.4 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB03993.1 - 0.033 14.0 0.4 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB03993.1 - 0.036 14.4 8.2 0.33 11.3 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Anti-TRAP PF15777.5 EGB03993.1 - 0.16 11.9 0.5 0.47 10.5 0.5 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein RdRP PF05183.12 EGB03994.1 - 8.6e-44 150.1 0.0 1.2e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase LSM PF01423.22 EGB03995.1 - 5.8e-13 48.3 0.1 7e-13 48.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGB03995.1 - 3.9e-05 23.7 0.0 4.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGB03995.1 - 0.046 13.8 0.1 0.063 13.4 0.1 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain LRR_6 PF13516.6 EGB03996.1 - 2.7e-08 33.2 0.3 0.012 15.6 0.1 5.7 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 EGB03996.1 - 0.00018 21.8 0.0 43 4.7 0.0 5.2 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) ABC1 PF03109.16 EGB03996.1 - 0.012 15.7 0.0 0.064 13.4 0.0 2.1 1 1 1 2 2 2 0 ABC1 family LRR_1 PF00560.33 EGB03996.1 - 0.021 15.3 0.0 1.9e+02 3.3 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat PC-Esterase PF13839.6 EGB03997.1 - 0.22 11.2 0.0 5.9 6.5 0.0 2.3 3 0 0 3 3 3 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Chloroa_b-bind PF00504.21 EGB03999.1 - 1.3e-38 133.1 0.1 1.9e-38 132.6 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 EGB04000.1 - 9.9e-39 133.4 0.1 1.5e-38 132.8 0.1 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TauD PF02668.16 EGB04001.1 - 3e-25 89.6 0.0 5.8e-25 88.6 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EGB04001.1 - 0.038 13.1 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 CsiD Pro_isomerase PF00160.21 EGB04002.1 - 7.8e-39 133.5 0.0 2e-38 132.2 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GCIP PF13324.6 EGB04003.1 - 5.3e-13 49.2 0.0 1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting AAA_19 PF13245.6 EGB04003.1 - 2.1e-10 41.1 0.0 6.4e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EGB04003.1 - 2.7e-10 40.3 0.0 4.2e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EGB04003.1 - 9.2e-10 38.2 0.0 8.4e-09 35.1 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 EGB04003.1 - 1.2e-09 38.0 0.0 3.1e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGB04003.1 - 5.7e-07 29.5 0.0 0.13 12.0 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase zf-CCHC PF00098.23 EGB04003.1 - 1.3e-06 28.2 1.6 1.3e-06 28.2 1.6 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGB04003.1 - 0.00021 21.2 1.3 0.00046 20.1 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF2075 PF09848.9 EGB04003.1 - 0.00057 19.2 0.1 1.1 8.5 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGB04003.1 - 0.00082 19.8 0.6 0.00082 19.8 0.6 5.2 4 2 2 7 7 6 1 AAA ATPase domain zf-CCHC_2 PF13696.6 EGB04003.1 - 0.38 10.6 1.9 0.7 9.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle ArfGap PF01412.18 EGB04004.1 - 3.9e-32 110.8 0.3 4.6e-32 110.6 0.3 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 EGB04004.1 - 0.036 14.0 2.1 0.22 11.5 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn_Tnp_IS1595 PF12760.7 EGB04004.1 - 0.046 13.7 0.3 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain V-SNARE PF05008.15 EGB04005.1 - 2.1e-07 31.2 0.5 1.4e-06 28.5 0.0 2.5 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGB04005.1 - 0.00087 19.5 1.3 0.012 15.8 1.3 2.7 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus COG2 PF06148.11 EGB04005.1 - 5.8 7.0 6.7 48 4.0 0.4 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Cyt-b5 PF00173.28 EGB04007.1 - 9.7e-13 48.1 0.0 1e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EGB04008.1 - 7.8e-13 48.8 24.1 1.1e-12 48.3 24.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGB04009.1 - 9.7e-13 48.1 0.0 1e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Chorion_1 PF01723.16 EGB04011.1 - 0.0045 17.0 2.7 0.18 11.8 0.4 2.5 1 1 1 2 2 2 2 Chorion protein DUF2754 PF10953.8 EGB04011.1 - 0.011 15.9 7.2 15 5.9 0.1 5.9 1 1 4 6 6 6 0 Protein of unknown function (DUF2754) DUF866 PF05907.13 EGB04011.1 - 0.014 15.3 0.0 14 5.6 0.0 3.2 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF866) Lamprin PF06403.11 EGB04011.1 - 0.018 15.0 3.0 0.73 9.8 0.4 2.2 1 1 1 2 2 2 0 Lamprin PAF-AH_p_II PF03403.13 EGB04014.1 - 0.26 9.8 0.1 0.4 9.1 0.1 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II CDC45 PF02724.14 EGB04014.1 - 0.31 9.3 5.6 0.48 8.7 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGB04014.1 - 0.49 9.8 11.1 0.75 9.2 11.1 1.2 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 EGB04014.1 - 1.1 8.1 9.4 1.6 7.7 9.4 1.1 1 0 0 1 1 1 0 Paf1 DUF3040 PF11239.8 EGB04014.1 - 1.4 9.3 7.3 0.34 11.2 2.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Mpp10 PF04006.12 EGB04014.1 - 1.9 6.8 9.8 2.7 6.3 9.8 1.1 1 0 0 1 1 1 0 Mpp10 protein ABC_tran PF00005.27 EGB04015.1 - 2e-21 76.9 0.0 3.5e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGB04015.1 - 8.1e-11 42.1 0.0 1.5e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGB04015.1 - 3.8e-05 23.2 0.0 0.0037 16.7 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGB04015.1 - 0.00037 20.4 0.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGB04015.1 - 0.00082 19.0 0.3 0.43 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EGB04015.1 - 0.001 18.4 0.1 0.0029 16.9 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 EGB04015.1 - 0.0043 17.5 1.0 0.0043 17.5 1.0 2.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB04015.1 - 0.0093 16.2 0.0 0.041 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGB04015.1 - 0.017 15.0 0.1 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EGB04015.1 - 0.044 13.5 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhyH PF05721.13 EGB04016.1 - 6.7e-10 39.6 0.1 1.3e-09 38.7 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Apolipo_F PF15148.6 EGB04016.1 - 0.23 10.9 0.3 0.69 9.4 0.1 1.8 2 0 0 2 2 2 0 Apolipoprotein F Ion_trans PF00520.31 EGB04017.1 - 6.8e-23 81.2 24.2 2.3e-11 43.4 8.1 2.2 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 EGB04017.1 - 5.1e-09 36.1 0.0 0.0041 17.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain TAT_ubiq PF07706.12 EGB04017.1 - 0.097 12.9 0.3 1.2e+02 3.0 0.0 3.4 3 0 0 3 3 3 0 Aminotransferase ubiquitination site DUF4258 PF14076.6 EGB04017.1 - 0.11 13.0 0.0 32 5.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Phospholip_A2_2 PF05826.12 EGB04017.1 - 0.41 10.9 5.5 11 6.3 0.5 2.4 2 0 0 2 2 2 0 Phospholipase A2 TMEM144 PF07857.12 EGB04018.1 - 9.4e-92 307.5 10.9 2.3e-90 303.0 10.9 2.0 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 EGB04018.1 - 7.4e-08 32.1 5.7 3.6e-06 26.5 1.2 2.4 2 0 0 2 2 2 2 Sugar transport protein Ureide_permease PF07168.11 EGB04018.1 - 0.14 10.9 16.8 0.03 13.1 2.5 2.5 1 1 1 2 2 2 0 Ureide permease WH2 PF02205.20 EGB04019.1 - 1.4e-05 24.8 0.8 0.00022 20.9 0.1 2.8 2 0 0 2 2 2 1 WH2 motif DRIM PF07539.12 EGB04019.1 - 0.18 10.1 0.0 0.46 8.7 0.0 1.6 2 0 0 2 2 2 0 Down-regulated in metastasis Arm PF00514.23 EGB04019.1 - 0.29 11.2 5.0 2.6 8.2 0.4 3.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Methyltransf_21 PF05050.12 EGB04020.1 - 2.1e-08 34.4 0.0 3.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Abhydrolase_1 PF00561.20 EGB04021.1 - 1e-06 28.6 0.1 1.8e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGB04021.1 - 6.3e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB04021.1 - 2.3e-05 23.8 0.1 0.00021 20.7 0.1 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 EGB04021.1 - 0.073 13.0 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) AXE1 PF05448.12 EGB04021.1 - 0.26 9.9 0.0 0.44 9.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) FERM_M PF00373.18 EGB04022.1 - 1.6e-05 25.3 0.0 3.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 FERM central domain Tyrosinase PF00264.20 EGB04023.1 - 7.6e-08 32.9 4.8 7.6e-08 32.9 4.8 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Arylsulfotrans PF05935.11 EGB04024.1 - 1.6e-16 60.2 0.1 1.8e-15 56.7 0.1 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB04024.1 - 0.002 17.6 0.3 0.0046 16.4 0.3 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PhyH PF05721.13 EGB04025.1 - 4.6e-08 33.6 0.2 4.2e-07 30.4 0.2 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1658 PF07871.11 EGB04025.1 - 0.39 10.7 2.2 1.2 9.2 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Gemini_AL2 PF01440.16 EGB04025.1 - 0.57 10.6 2.0 0.64 10.5 0.0 2.1 2 1 1 3 3 3 0 Geminivirus AL2 protein Pkinase PF00069.25 EGB04026.1 - 2.8e-36 125.3 0.0 3.4e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04026.1 - 4.6e-33 114.6 0.0 7.5e-33 113.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB04026.1 - 2.4e-06 27.7 0.9 0.037 13.9 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB04026.1 - 0.02 13.7 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase LSM PF01423.22 EGB04028.1 - 1.9e-20 72.3 0.0 2.3e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EGB04028.1 - 0.042 14.0 0.1 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Sod_Cu PF00080.20 EGB04029.1 - 4.3e-42 143.7 37.1 6.7e-09 36.1 0.2 8.0 6 1 0 6 6 6 6 Copper/zinc superoxide dismutase (SODC) Abhydrolase_5 PF12695.7 EGB04029.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_9 PF13371.6 EGB04029.1 - 0.00011 22.3 1.1 0.00043 20.4 1.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Hydrolase_4 PF12146.8 EGB04029.1 - 0.093 12.0 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGB04029.1 - 0.25 11.0 0.0 0.44 10.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein ECH_1 PF00378.20 EGB04030.1 - 5.9e-30 104.4 0.8 7e-30 104.2 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB04030.1 - 1.2e-20 74.3 0.3 2e-20 73.6 0.3 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pro_isomerase PF00160.21 EGB04031.1 - 3e-45 154.3 0.0 3.7e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lipase_GDSL_2 PF13472.6 EGB04032.1 - 1.1e-18 68.3 1.0 3e-18 66.9 1.0 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB04032.1 - 6.6e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CDC27 PF09507.10 EGB04032.1 - 1.4 8.2 18.6 3.7 6.8 18.6 1.7 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ank_2 PF12796.7 EGB04033.1 - 0.00035 21.1 0.0 0.0048 17.4 0.1 2.7 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB04033.1 - 0.0053 17.3 0.2 2.6 8.7 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) LRR_4 PF12799.7 EGB04033.1 - 0.013 15.9 0.0 47 4.6 0.0 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Ank PF00023.30 EGB04033.1 - 0.028 14.8 2.1 0.27 11.8 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 EGB04033.1 - 0.034 14.7 3.2 3.3 8.6 0.2 4.3 5 0 0 5 5 5 0 Ankyrin repeat LRR_6 PF13516.6 EGB04033.1 - 0.092 12.8 0.0 15 6.0 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat DUF3638 PF12340.8 EGB04034.1 - 7.2e-27 94.2 0.0 1.5e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) MBOAT PF03062.19 EGB04034.1 - 1e-20 74.4 0.5 1.8e-20 73.6 0.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3645 PF12359.8 EGB04034.1 - 2.6e-14 52.3 0.1 7.4e-14 50.8 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Thioredoxin_8 PF13905.6 EGB04034.1 - 3.1e-10 40.3 0.0 5.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like ubiquitin PF00240.23 EGB04034.1 - 3.7e-09 36.2 0.0 6.1e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Methyltransf_16 PF10294.9 EGB04034.1 - 0.0002 21.1 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubiquitin_2 PF14560.6 EGB04034.1 - 0.00066 20.1 0.0 0.03 14.8 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-like domain EF-hand_6 PF13405.6 EGB04034.1 - 0.00069 19.3 3.1 1.2 9.2 0.4 3.8 4 0 0 4 4 3 2 EF-hand domain CS PF04969.16 EGB04034.1 - 0.0017 19.3 0.0 0.0067 17.4 0.0 1.9 2 0 0 2 2 2 1 CS domain MTS PF05175.14 EGB04034.1 - 0.002 17.7 0.1 0.0056 16.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGB04034.1 - 0.0083 16.8 0.0 0.034 14.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain EF-hand_7 PF13499.6 EGB04034.1 - 0.021 15.3 0.0 0.073 13.5 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair GP79 PF17463.2 EGB04034.1 - 0.044 13.8 0.0 0.31 11.1 0.0 2.6 1 0 0 1 1 1 0 Gene product 79 MBT PF02820.18 EGB04034.1 - 0.05 14.0 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 mbt repeat SH3_15 PF18346.1 EGB04034.1 - 0.083 13.2 0.1 0.48 10.8 0.1 2.4 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain EF-hand_1 PF00036.32 EGB04034.1 - 0.23 11.1 5.1 0.81 9.4 0.4 3.5 4 0 0 4 4 4 0 EF hand LicD PF04991.13 EGB04035.1 - 0.0043 17.2 0.2 1.9 8.5 0.0 2.2 2 0 0 2 2 2 2 LicD family eIF-5a PF01287.20 EGB04035.1 - 0.64 10.2 1.5 13 6.0 0.1 2.9 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Histone PF00125.24 EGB04036.1 - 5.4e-19 68.8 0.4 6.5e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB04036.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB04036.1 - 0.0039 17.7 0.0 0.0061 17.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB04036.1 - 0.054 13.5 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein Rer1 PF03248.13 EGB04037.1 - 8e-55 185.2 4.4 1.1e-54 184.8 4.4 1.1 1 0 0 1 1 1 1 Rer1 family PEN-2 PF10251.9 EGB04037.1 - 1 9.8 7.4 0.34 11.3 3.2 2.0 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF2208 PF09973.9 EGB04037.1 - 3.7 7.1 8.4 0.25 11.0 3.4 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) ABC_tran PF00005.27 EGB04038.1 - 4.7e-48 163.2 0.0 9.6e-23 81.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGB04038.1 - 1.8e-18 66.3 3.5 1.8e-18 66.3 3.5 4.6 4 1 1 5 5 3 1 ABC transporter AAA_21 PF13304.6 EGB04038.1 - 4.1e-18 66.2 0.0 0.00032 20.6 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB04038.1 - 4.2e-12 46.0 2.8 0.00025 20.5 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB04038.1 - 1.5e-08 34.2 0.0 0.00077 19.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EGB04038.1 - 4e-08 33.4 1.6 0.0089 15.8 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 EGB04038.1 - 1.2e-06 28.9 0.5 0.1 13.0 0.1 3.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB04038.1 - 4.3e-06 27.2 0.7 0.036 14.5 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 EGB04038.1 - 4.6e-06 26.9 0.3 0.13 12.4 0.0 3.3 2 1 1 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGB04038.1 - 4.8e-06 26.6 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGB04038.1 - 6.1e-06 26.9 0.7 0.00061 20.4 0.2 4.8 4 1 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EGB04038.1 - 7e-06 26.4 0.0 0.026 14.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGB04038.1 - 9.1e-06 26.0 0.0 0.014 15.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EGB04038.1 - 1.3e-05 25.8 0.0 0.073 13.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 EGB04038.1 - 4.8e-05 23.7 0.0 0.26 11.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 EGB04038.1 - 0.00012 21.9 0.1 0.076 12.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EGB04038.1 - 0.00022 21.2 0.0 0.039 14.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGB04038.1 - 0.00032 20.5 0.2 1.6 8.4 0.0 3.3 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EGB04038.1 - 0.00048 20.2 0.1 0.81 9.8 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EGB04038.1 - 0.00093 18.8 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 EGB04038.1 - 0.0014 18.7 0.0 3.4 7.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain ATP_bind_1 PF03029.17 EGB04038.1 - 0.0015 18.3 0.0 2.6 7.8 0.0 2.7 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 EGB04038.1 - 0.0034 17.4 0.0 3.5 7.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MukB PF04310.12 EGB04038.1 - 0.0052 16.6 0.3 7.6 6.3 0.0 3.4 3 0 0 3 3 3 0 MukB N-terminal NTPase_1 PF03266.15 EGB04038.1 - 0.0054 16.6 0.0 1.6 8.6 0.1 2.8 2 1 0 2 2 2 1 NTPase NACHT PF05729.12 EGB04038.1 - 0.0076 16.2 0.8 2.4 8.0 0.1 2.5 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.22 EGB04038.1 - 0.011 15.4 0.1 0.92 9.1 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 EGB04038.1 - 0.012 15.3 5.4 0.11 12.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 EGB04038.1 - 0.012 15.2 0.0 1.3 8.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EGB04038.1 - 0.032 13.9 0.0 12 5.5 0.0 2.9 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.22 EGB04038.1 - 0.039 13.1 0.0 5.2 6.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 EGB04038.1 - 0.053 13.8 0.2 0.94 9.8 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Cytidylate_kin PF02224.18 EGB04038.1 - 0.056 13.2 2.9 2.3 7.9 0.1 2.7 3 0 0 3 3 2 0 Cytidylate kinase PduV-EutP PF10662.9 EGB04038.1 - 0.062 13.0 0.0 6.2 6.6 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EGB04038.1 - 0.07 13.0 0.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Roc PF08477.13 EGB04038.1 - 0.082 13.1 0.0 5.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EGB04038.1 - 0.11 12.6 2.3 2.8 8.0 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain G-alpha PF00503.20 EGB04038.1 - 0.11 11.6 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit cobW PF02492.19 EGB04038.1 - 0.12 11.9 0.0 6 6.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EGB04038.1 - 5.9 7.3 7.5 7.4 7.0 0.0 3.4 3 0 0 3 3 2 0 AAA domain GTP_EFTU PF00009.27 EGB04039.1 - 6.2e-59 198.8 0.1 9.2e-59 198.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGB04039.1 - 6.2e-26 90.6 0.0 1.6e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGB04039.1 - 2.4e-19 69.2 0.0 6.3e-19 67.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGB04039.1 - 4.2e-14 52.4 0.0 9.6e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGB04039.1 - 1.5e-13 50.9 1.2 3.1e-13 49.9 0.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGB04039.1 - 0.00027 21.0 0.0 0.00075 19.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase bZIP_2 PF07716.15 EGB04040.1 - 0.17 12.0 5.6 0.36 11.0 5.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Apt1 PF10351.9 EGB04041.1 - 4.7 6.0 5.4 4.3 6.1 5.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cpn60_TCP1 PF00118.24 EGB04042.1 - 5.5e-89 299.0 4.3 3e-66 224.1 0.2 3.1 3 0 0 3 3 3 3 TCP-1/cpn60 chaperonin family DUF4136 PF13590.6 EGB04042.1 - 0.031 14.8 0.1 8.5 7.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4136) MOZART1 PF12554.8 EGB04042.1 - 0.13 12.1 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Ank_4 PF13637.6 EGB04043.1 - 1.2e-15 57.6 0.4 1.8e-08 34.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB04043.1 - 6.8e-11 42.6 0.1 8.5e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB04043.1 - 1.2e-09 38.2 0.7 9.3e-07 29.0 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB04043.1 - 8.2e-08 31.9 0.3 0.002 18.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGB04043.1 - 3.7e-07 30.3 2.0 6.1e-05 23.3 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat PAS_9 PF13426.7 EGB04044.1 - 3.7e-10 40.0 0.0 7.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EGB04044.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold TetR_C_29 PF17938.1 EGB04044.1 - 0.066 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain WD40 PF00400.32 EGB04045.1 - 1.7e-48 161.6 23.2 1.6e-08 35.0 0.2 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04045.1 - 6.4e-28 96.9 1.7 3.2e-05 24.1 0.0 7.0 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB04045.1 - 6.5e-09 35.9 0.0 0.00043 20.2 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EGB04045.1 - 5.1e-08 32.6 0.5 1.1e-07 31.5 0.5 1.6 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 EGB04045.1 - 0.0017 17.4 0.1 2.8 6.8 0.0 4.1 3 3 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EGB04045.1 - 0.0071 15.4 0.3 0.94 8.5 0.0 3.1 4 0 0 4 4 4 1 Coatomer WD associated region IKI3 PF04762.12 EGB04045.1 - 0.0085 14.2 0.3 2 6.3 0.0 3.1 3 0 0 3 3 3 1 IKI3 family Nbas_N PF15492.6 EGB04045.1 - 0.021 14.1 0.3 0.97 8.7 0.0 3.2 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EGB04045.1 - 0.41 10.6 2.9 75 3.4 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Plus-3 PF03126.18 EGB04046.1 - 9.8e-30 103.3 0.0 3.7e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 Plus-3 domain Mito_carr PF00153.27 EGB04047.1 - 3.3e-11 42.9 8.0 0.00049 20.0 0.4 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Actin PF00022.19 EGB04048.1 - 1.2e-68 231.6 0.0 9.4e-68 228.7 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGB04048.1 - 0.015 14.1 0.0 4.3 6.1 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein AnmK PF03702.14 EGB04048.1 - 0.17 11.0 0.1 1 8.4 0.0 1.9 2 0 0 2 2 2 0 Anhydro-N-acetylmuramic acid kinase Pkinase PF00069.25 EGB04049.1 - 1.8e-63 214.4 0.0 2e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04049.1 - 2.8e-39 135.0 0.0 3.5e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04049.1 - 7.9e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB04049.1 - 0.0023 17.3 1.0 0.011 15.1 1.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB04049.1 - 0.013 15.5 0.1 0.032 14.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB04049.1 - 0.12 11.3 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain IQ PF00612.27 EGB04050.1 - 0.1 12.4 1.8 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif ketoacyl-synt PF00109.26 EGB04051.1 - 3e-12 46.7 3.3 3.3e-12 46.5 3.3 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF5455 PF17537.2 EGB04051.1 - 0.027 14.9 1.1 0.031 14.7 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5455) CD20 PF04103.15 EGB04051.1 - 0.028 14.5 4.5 0.031 14.4 4.5 1.0 1 0 0 1 1 1 0 CD20-like family SLATT_6 PF18169.1 EGB04051.1 - 0.055 13.1 1.4 0.06 12.9 1.4 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 SLATT_5 PF18160.1 EGB04051.1 - 0.95 8.7 4.1 1.1 8.6 4.1 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 HMG_CoA_synt_N PF01154.17 EGB04052.1 - 6.9e-22 78.1 0.1 7.5e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PP-binding PF00550.25 EGB04053.1 - 9.8e-12 45.1 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 EGB04053.1 - 3.3e-07 30.1 0.7 3.4e-06 26.8 0.7 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SNF2_N PF00176.23 EGB04055.1 - 5.1e-08 32.0 0.5 9.2e-06 24.6 0.0 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain AAA_25 PF13481.6 EGB04055.1 - 0.056 13.0 0.0 0.056 13.0 0.0 1.0 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.31 EGB04056.1 - 1.1e-07 32.1 0.0 1.6e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EF-hand_8 PF13833.6 EGB04058.1 - 0.0013 18.6 0.2 0.0034 17.2 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB04058.1 - 0.0063 16.0 0.4 0.034 13.7 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB04058.1 - 0.017 15.0 0.2 0.084 12.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EGB04058.1 - 0.025 15.0 0.2 0.21 12.1 0.2 2.3 1 1 0 1 1 1 0 EF-hand domain pair DNA_pol3_a_NI PF14480.6 EGB04059.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I DNA_methylase PF00145.17 EGB04060.1 - 0.0032 16.9 0.0 0.011 15.0 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase GPS2_interact PF15784.5 EGB04060.1 - 0.0093 16.4 0.2 0.92 10.0 0.0 2.7 2 0 0 2 2 2 1 G-protein pathway suppressor 2-interacting domain NPV_P10 PF05531.12 EGB04060.1 - 0.6 10.6 2.7 1.8 9.1 0.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 EGB04060.1 - 2.4 8.4 4.6 2 8.7 1.3 2.6 2 1 1 3 3 3 0 Haemolysin XhlA Lipase_3 PF01764.25 EGB04061.1 - 0.00013 21.9 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF2457 PF10446.9 EGB04062.1 - 0.48 9.5 14.6 0.67 9.0 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EGB04062.1 - 1.2 7.3 7.9 1.5 7.0 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGB04062.1 - 1.8 6.7 12.2 2.3 6.3 12.2 1.0 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 EGB04062.1 - 2.7 8.3 10.2 4.4 7.6 10.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 EGB04062.1 - 2.8 7.3 11.7 3.8 6.8 11.7 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 EGB04062.1 - 4.1 7.4 13.4 5.7 7.0 13.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein ketoacyl-synt PF00109.26 EGB04063.1 - 2.7e-14 53.4 2.6 4.2e-14 52.7 2.6 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ketoacyl-synt PF00109.26 EGB04064.1 - 2.9e-23 82.8 10.7 3.2e-23 82.6 10.7 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGB04064.1 - 0.0099 15.7 4.5 0.018 14.9 2.5 2.3 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding PF00501.28 EGB04065.1 - 4e-20 71.8 0.0 4.3e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGB04066.1 - 2.8e-11 43.5 5.9 3.6e-11 43.1 5.9 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB04066.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGB04067.1 - 1.2e-23 84.0 10.9 1.4e-23 83.8 10.9 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGB04067.1 - 0.0014 18.4 5.0 0.0029 17.4 2.8 2.3 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 EGB04068.1 - 5.3e-21 75.3 0.3 5.7e-21 75.1 0.3 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ECH_1 PF00378.20 EGB04069.1 - 8.6e-06 25.2 0.1 1e-05 25.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 EGB04070.1 - 1.2e-23 84.0 10.9 1.4e-23 83.8 10.9 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGB04070.1 - 0.0014 18.4 5.0 0.0029 17.4 2.8 2.3 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGB04071.1 - 5.6e-21 75.3 2.9 7.8e-21 74.8 2.9 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB04071.1 - 4.7e-05 23.4 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGB04072.1 - 6.2e-29 101.3 6.8 7.5e-29 101.1 6.8 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EGB04072.1 - 0.016 14.6 0.7 0.019 14.3 0.7 1.1 1 0 0 1 1 1 0 Thiolase, N-terminal domain HMG_CoA_synt_N PF01154.17 EGB04073.1 - 8.9e-29 100.6 0.2 9.3e-29 100.5 0.2 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ADH_zinc_N PF00107.26 EGB04074.1 - 3.3e-14 53.0 0.0 4.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB04074.1 - 0.00016 21.5 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGB04074.1 - 0.00058 20.9 0.0 0.0017 19.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.26 EGB04075.1 - 1.9e-22 80.0 4.1 2.2e-22 79.9 4.1 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ketoacyl-synt PF00109.26 EGB04076.1 - 3.4e-27 95.6 7.3 4.3e-27 95.3 7.3 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGB04076.1 - 0.0095 15.8 0.3 0.031 14.1 0.1 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EGB04076.1 - 0.031 13.6 0.4 0.041 13.2 0.4 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Astacin PF01400.24 EGB04076.1 - 0.11 12.1 0.2 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) HMG_CoA_synt_N PF01154.17 EGB04077.1 - 4e-24 85.4 0.0 4.3e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 EGB04078.1 - 1.4e-25 90.4 2.8 2.1e-25 89.7 2.8 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB04078.1 - 2.4e-06 27.6 0.1 7.5e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EGB04078.1 - 0.0014 18.4 1.6 0.051 13.4 1.6 2.3 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGB04079.1 - 9.1e-35 120.4 11.9 1.1e-34 120.2 11.9 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EGB04079.1 - 0.0016 17.8 0.9 0.0024 17.3 0.9 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF3586 PF12131.8 EGB04079.1 - 0.14 12.4 2.1 0.23 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) SURNod19 PF07712.12 EGB04080.1 - 1.9e-14 53.2 0.1 2.3e-12 46.3 0.0 2.7 2 1 0 2 2 2 2 Stress up-regulated Nod 19 EF-hand_1 PF00036.32 EGB04081.1 - 1.3e-16 58.8 6.8 5.7e-08 31.8 1.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGB04081.1 - 7.1e-15 53.6 2.8 5.2e-05 22.8 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGB04081.1 - 8.9e-15 54.9 2.8 1.6e-12 47.7 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB04081.1 - 4.4e-10 38.6 7.4 0.00014 21.1 1.8 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGB04081.1 - 6.7e-08 32.3 0.4 6.7e-08 32.3 0.4 3.2 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_4 PF12763.7 EGB04081.1 - 0.00013 21.9 0.2 0.00013 21.9 0.2 2.5 2 2 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGB04081.1 - 0.007 16.7 0.4 0.076 13.4 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain zf-RRPl_C4 PF17026.5 EGB04081.1 - 0.016 15.3 1.9 0.034 14.2 1.9 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2180 PF09947.9 EGB04081.1 - 0.079 12.9 0.6 0.079 12.9 0.6 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Prok-RING_1 PF14446.6 EGB04081.1 - 0.34 10.9 7.1 0.045 13.7 2.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-CHY PF05495.12 EGB04081.1 - 0.46 11.0 4.0 1.1 9.8 4.0 1.7 1 0 0 1 1 1 0 CHY zinc finger SR1P PF13790.6 EGB04081.1 - 8.3 6.6 8.1 0.95 9.6 0.7 2.5 2 0 0 2 2 2 0 SR1 protein PIF1 PF05970.14 EGB04082.1 - 0.035 13.3 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase RsgA_GTPase PF03193.16 EGB04082.1 - 0.039 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EGB04082.1 - 0.084 13.4 0.1 0.13 12.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EGB04082.1 - 0.13 12.6 0.1 0.79 10.1 0.0 2.4 3 0 0 3 3 3 0 RNA helicase Dysbindin PF04440.16 EGB04083.1 - 1.9 8.7 8.6 4.3 7.5 0.0 2.9 3 0 0 3 3 3 0 Dysbindin (Dystrobrevin binding protein 1) ATP-cone PF03477.16 EGB04084.1 - 0.00013 22.5 0.0 0.00055 20.5 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain rve PF00665.26 EGB04086.1 - 2.9e-09 37.1 0.0 1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Pox_D5 PF03288.16 EGB04086.1 - 0.028 14.9 1.2 10 6.7 0.0 3.6 4 0 0 4 4 4 0 Poxvirus D5 protein-like RelB_N PF18506.1 EGB04087.1 - 0.15 11.9 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain DUF3504 PF12012.8 EGB04088.1 - 0.042 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) DUF4746 PF15928.5 EGB04088.1 - 0.091 12.2 1.6 0.15 11.5 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DivIC PF04977.15 EGB04089.1 - 0.61 9.9 3.2 1.7 8.5 3.2 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF134 PF02001.16 EGB04089.1 - 1 9.9 3.3 1.2 9.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF134 APG6_N PF17675.1 EGB04089.1 - 5.3 7.6 7.3 0.65 10.5 2.7 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Sel1 PF08238.12 EGB04090.1 - 4e-09 36.8 0.8 0.00076 20.1 0.1 2.9 3 0 0 3 3 3 2 Sel1 repeat zf-MYND PF01753.18 EGB04090.1 - 2.8e-05 24.1 11.4 2.8e-05 24.1 11.4 2.5 3 0 0 3 3 3 1 MYND finger Ketoacyl-synt_C PF02801.22 EGB04091.1 - 7.5e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HMG_CoA_synt_N PF01154.17 EGB04092.1 - 9.6e-22 77.7 0.1 1e-21 77.6 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal cNMP_binding PF00027.29 EGB04093.1 - 7.7e-17 61.2 0.1 8.3e-17 61.1 0.1 1.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Helicase_C PF00271.31 EGB04096.1 - 0.00036 20.8 0.0 0.00049 20.4 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EF-hand_6 PF13405.6 EGB04097.1 - 2.4e-07 30.1 1.0 0.0025 17.6 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB04097.1 - 1.7e-06 27.2 0.5 0.0034 16.8 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB04097.1 - 7.6e-06 26.3 0.5 1.1e-05 25.8 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB04097.1 - 9.2e-05 21.8 2.0 0.12 11.9 0.1 2.4 2 0 0 2 2 2 2 EF hand Folate_carrier PF01770.18 EGB04098.1 - 0.63 8.7 5.0 0.086 11.6 0.5 1.7 2 0 0 2 2 2 0 Reduced folate carrier COX4 PF02936.14 EGB04100.1 - 3 7.8 12.1 0.41 10.7 0.2 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV GCD14 PF08704.10 EGB04101.1 - 0.034 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit BssB_TutG PF18512.1 EGB04101.1 - 1.6 8.7 4.2 3.5 7.6 1.4 2.4 2 0 0 2 2 2 0 Benzylsuccinate synthase beta subunit Nuc_deoxyrib_tr PF05014.15 EGB04103.1 - 0.0042 17.1 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 EGB04103.1 - 0.017 15.5 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like NAD_binding_8 PF13450.6 EGB04106.1 - 1.3e-05 25.3 0.2 0.00013 22.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EGB04106.1 - 0.082 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like ketoacyl-synt PF00109.26 EGB04108.1 - 3.2e-06 26.9 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 EGB04109.1 - 8e-08 32.5 0.1 2.1e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 EGB04110.1 - 1.5e-16 60.8 5.2 1.7e-16 60.6 5.2 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Sulfotransfer_3 PF13469.6 EGB04111.1 - 0.00058 20.3 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family AMP-binding PF00501.28 EGB04111.1 - 0.0025 16.5 0.0 0.0037 15.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 EGB04112.1 - 3.1e-16 59.0 0.4 3.3e-16 58.9 0.4 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGB04113.1 - 5.6e-17 62.2 1.4 5.8e-17 62.1 1.4 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Abhydrolase_6 PF12697.7 EGB04114.1 - 6.6e-14 53.0 1.5 1.1e-13 52.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family ketoacyl-synt PF00109.26 EGB04114.1 - 3.2e-08 33.5 0.3 1e-07 31.8 0.1 2.0 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Hydrolase_4 PF12146.8 EGB04114.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB04114.1 - 0.00015 21.6 0.2 0.00036 20.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ketoacyl-synt_C PF02801.22 EGB04114.1 - 0.00054 20.0 1.1 0.0016 18.4 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain YtxH PF12732.7 EGB04114.1 - 0.056 14.0 0.5 0.15 12.6 0.5 1.7 1 0 0 1 1 1 0 YtxH-like protein Abhydrolase_1 PF00561.20 EGB04115.1 - 0.014 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EGB04115.1 - 0.048 13.2 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 EGB04115.1 - 0.058 13.5 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 EGB04115.1 - 0.071 12.0 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EGB04115.1 - 0.08 13.5 0.0 0.16 12.6 0.0 1.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family ABC1 PF03109.16 EGB04116.1 - 1.8e-25 89.4 0.0 3.9e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Lipase_3 PF01764.25 EGB04117.1 - 0.00054 19.8 0.0 0.0016 18.3 0.0 1.9 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGB04117.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 YqfD PF06898.11 EGB04117.1 - 0.16 10.8 0.4 0.25 10.1 0.4 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD LMBR1 PF04791.16 EGB04118.1 - 0.14 11.0 1.6 0.21 10.5 1.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein WDCP PF15390.6 EGB04118.1 - 0.73 8.1 10.7 1 7.6 10.7 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family AbiH PF14253.6 EGB04118.1 - 1.8 8.3 4.2 9.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH IMUP PF15761.5 EGB04119.1 - 0.00053 20.6 14.7 0.00053 20.6 14.7 3.3 3 1 1 4 4 4 1 Immortalisation up-regulated protein SR-25 PF10500.9 EGB04119.1 - 0.0059 16.2 32.2 0.016 14.8 15.6 2.6 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein X PF00739.19 EGB04119.1 - 0.52 10.4 7.3 1.3 9.1 0.1 3.2 3 0 0 3 3 3 0 Trans-activation protein X Drc1-Sld2 PF11719.8 EGB04119.1 - 4.7 6.6 27.2 1.1 8.7 8.8 2.5 1 1 1 2 2 2 0 DNA replication and checkpoint protein CCDC106 PF15794.5 EGB04119.1 - 6.4 6.4 18.6 2.9 7.5 1.7 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 AP_endonuc_2 PF01261.24 EGB04120.1 - 0.048 13.1 0.3 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ACCA PF03255.14 EGB04122.1 - 0.0018 18.2 0.5 8.5 6.2 0.0 4.0 3 2 2 5 5 5 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fip1 PF05182.13 EGB04122.1 - 0.11 12.0 0.9 21 4.7 0.0 2.8 3 0 0 3 3 3 0 Fip1 motif Hum_adeno_E3A PF05393.11 EGB04122.1 - 0.18 11.8 0.0 36 4.4 0.0 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein PHD PF00628.29 EGB04124.1 - 0.091 12.7 7.2 0.16 11.8 7.2 1.4 1 0 0 1 1 1 0 PHD-finger DZR PF12773.7 EGB04124.1 - 0.12 12.4 4.6 1.4 9.0 4.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-PHD-like PF15446.6 EGB04124.1 - 0.58 9.8 5.5 1.1 8.8 5.5 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DivIC PF04977.15 EGB04124.1 - 1.2 9.0 3.2 3.1 7.6 3.2 1.7 1 0 0 1 1 1 0 Septum formation initiator C1_1 PF00130.22 EGB04124.1 - 2.4 8.1 5.7 2.5 8.0 4.3 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF134 PF02001.16 EGB04124.1 - 4.4 7.9 4.7 2.3 8.8 1.1 2.4 3 0 0 3 3 3 0 Protein of unknown function DUF134 CSN8_PSD8_EIF3K PF10075.9 EGB04126.1 - 4.5e-10 39.7 0.0 5.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Pkinase PF00069.25 EGB04127.1 - 9.3e-53 179.3 0.0 1.3e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04127.1 - 8.3e-27 94.1 0.0 1.3e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB04127.1 - 0.0025 16.8 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGB04127.1 - 0.0042 16.5 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB04127.1 - 0.0069 16.3 4.9 0.013 15.4 1.7 2.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB04127.1 - 0.017 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LRR_9 PF14580.6 EGB04129.1 - 2.2e-14 53.4 6.6 3.3e-13 49.5 3.9 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 EGB04129.1 - 2.1e-13 50.2 28.0 1.1e-06 28.8 3.3 4.4 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB04129.1 - 1.3e-07 31.3 19.6 0.00027 20.6 9.8 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 EGB04129.1 - 6.3 7.1 14.8 7.2 6.9 0.2 4.5 4 0 0 4 4 4 0 Leucine Rich repeat FragX_IP PF05994.11 EGB04130.1 - 1e-194 649.1 0.0 3.1e-102 343.2 0.1 2.2 1 1 1 2 2 2 2 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 EGB04130.1 - 0.00078 18.8 0.3 0.0014 18.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) TLD PF07534.16 EGB04131.1 - 1.2e-08 35.3 0.0 4.6e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 TLD Cys_rich_CWC PF14375.6 EGB04131.1 - 0.077 13.4 3.3 2 8.9 2.0 2.7 2 0 0 2 2 2 0 Cysteine-rich CWC Nuc_sug_transp PF04142.15 EGB04132.1 - 5.4e-100 334.6 12.2 6.2e-100 334.4 12.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB04132.1 - 9.2e-07 29.1 17.9 8e-05 22.8 0.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 EGB04132.1 - 0.0017 18.0 2.9 0.0035 17.0 2.4 1.8 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter DUF1761 PF08570.10 EGB04132.1 - 1.5 9.1 12.0 5.5 7.3 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) Pkinase PF00069.25 EGB04133.1 - 1.2e-45 155.9 0.1 8.2e-38 130.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04133.1 - 1.3e-19 70.5 0.0 1.8e-16 60.2 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase C2 PF00168.30 EGB04133.1 - 1.4e-18 67.1 0.0 1e-06 29.0 0.0 4.4 2 2 0 3 3 3 3 C2 domain Kinase-like PF14531.6 EGB04133.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB04133.1 - 0.026 13.3 0.1 0.057 12.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EGB04133.1 - 0.097 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 EGB04134.1 - 2.4e-29 101.0 28.9 3.3e-05 24.6 0.7 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04134.1 - 6.1e-11 42.5 0.0 0.0022 18.2 0.2 4.4 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGB04134.1 - 0.00038 19.9 0.1 0.0028 17.0 0.0 2.3 2 1 1 3 3 3 1 WD40-like domain WD40 PF00400.32 EGB04135.1 - 2.9e-17 62.7 19.2 9.3e-05 23.1 1.5 8.8 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04135.1 - 7.6e-07 29.4 0.0 0.15 12.4 0.0 5.8 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB04135.1 - 0.099 11.6 1.8 1.9 7.4 0.0 3.6 5 0 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB04135.1 - 0.1 12.5 0.0 0.51 10.2 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A CYTH PF01928.21 EGB04135.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 CYTH domain BolA PF01722.18 EGB04136.1 - 0.0067 16.7 0.0 0.044 14.1 0.0 2.4 2 0 0 2 2 2 1 BolA-like protein InvH PF04741.12 EGB04136.1 - 0.078 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF737 PF05300.11 EGB04136.1 - 2.9 8.2 12.2 0.086 13.2 0.9 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF737) Kelch_1 PF01344.25 EGB04137.1 - 6.8e-39 131.2 18.5 5.1e-08 32.4 0.3 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGB04137.1 - 6.4e-36 122.1 18.9 3.2e-07 30.3 0.2 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGB04137.1 - 7.5e-36 121.7 22.8 6.9e-09 35.8 0.1 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EGB04137.1 - 7.4e-34 114.5 19.6 8.7e-07 28.7 0.5 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 EGB04137.1 - 2e-31 107.2 14.4 2.4e-06 27.6 1.3 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 EGB04137.1 - 1.7e-19 69.4 18.1 0.00013 21.9 0.3 6.1 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 EGB04137.1 - 0.0076 16.3 0.2 0.018 15.1 0.2 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch MORN PF02493.20 EGB04138.1 - 2e-39 131.2 51.3 3.2e-06 26.7 0.5 9.1 9 0 0 9 9 9 9 MORN repeat MORN_2 PF07661.13 EGB04138.1 - 0.009 16.1 5.5 3.1 8.3 0.1 4.1 4 0 0 4 4 4 2 MORN repeat variant DnaJ PF00226.31 EGB04139.1 - 9.4e-13 48.1 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 EGB04140.1 - 9e-17 61.2 19.9 0.0034 18.2 0.1 9.8 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04140.1 - 0.00047 20.4 0.0 0.35 11.2 0.0 4.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RalF_SCD PF18248.1 EGB04140.1 - 0.18 11.8 0.0 0.47 10.4 0.0 1.6 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain FHA PF00498.26 EGB04141.1 - 6.6e-08 32.8 0.1 9e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGB04141.1 - 9.8e-05 22.6 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Corazonin PF17308.2 EGB04141.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Pro-corazonin DUF4201 PF13870.6 EGB04142.1 - 5.3e-40 137.0 23.2 5.3e-40 137.0 23.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) SecD-TM1 PF13721.6 EGB04142.1 - 0.0056 17.1 8.2 0.032 14.7 0.6 3.2 1 1 3 4 4 4 2 SecD export protein N-terminal TM region LegC3_N PF18654.1 EGB04142.1 - 2.5 7.2 25.0 0.15 11.3 9.7 2.2 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain COG5 PF10392.9 EGB04142.1 - 4.9 7.3 12.4 0.29 11.3 1.8 3.1 2 1 1 4 4 4 0 Golgi transport complex subunit 5 Fez1 PF06818.15 EGB04142.1 - 6.4 7.2 29.1 1.1e+02 3.2 22.2 2.9 1 1 1 2 2 2 0 Fez1 Sulfatase PF00884.23 EGB04143.1 - 9.7e-30 104.0 0.0 1.4e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Myb_DNA-binding PF00249.31 EGB04144.1 - 2.8e-30 104.2 3.8 8.3e-15 54.7 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB04144.1 - 3.6e-22 78.4 2.9 1.3e-14 54.1 0.2 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB04144.1 - 9.9e-05 22.2 0.3 0.00024 20.9 0.1 1.7 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EGB04144.1 - 0.0051 17.2 3.8 0.056 13.8 0.2 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EGB04144.1 - 0.01 15.9 0.1 0.21 11.6 0.0 2.1 1 1 1 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 EGB04144.1 - 0.018 15.3 0.8 4.5 7.5 0.1 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SNF2_N PF00176.23 EGB04145.1 - 2.1e-29 102.3 0.0 3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB04145.1 - 7.8e-12 45.5 0.1 1.7e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB04145.1 - 1.1e-07 32.0 0.0 2.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 EGB04145.1 - 0.0075 15.7 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein DEAD_2 PF06733.15 EGB04145.1 - 0.043 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 HGTP_anticodon PF03129.20 EGB04146.1 - 1.9e-20 72.8 0.0 4.5e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGB04146.1 - 1e-07 32.1 0.0 3e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4145 PF13643.6 EGB04146.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Cullin PF00888.22 EGB04147.1 - 1.8e-16 59.9 0.1 3.3e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EGB04147.1 - 5.5e-14 52.4 0.5 6.1e-13 49.1 0.3 2.4 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 DUF2587 PF10759.9 EGB04147.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) RRM_1 PF00076.22 EGB04148.1 - 4.9e-68 224.9 0.2 9.5e-20 70.2 0.0 5.1 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGB04148.1 - 3.9e-29 100.6 1.5 1.1e-28 99.1 0.3 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 EGB04148.1 - 1.1e-07 31.7 0.1 0.012 15.6 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGB04148.1 - 3.8e-07 29.7 0.0 0.089 12.4 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB04148.1 - 0.00043 20.4 0.1 2.3 8.4 0.0 4.5 4 1 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 EGB04148.1 - 0.0043 17.1 0.1 0.99 9.5 0.0 4.0 5 0 0 5 5 5 1 Limkain b1 SET_assoc PF11767.8 EGB04148.1 - 0.05 13.2 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated SET PF00856.28 EGB04149.1 - 0.17 12.3 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 SET domain Thioredoxin PF00085.20 EGB04150.1 - 4.1e-14 52.4 0.0 4.3e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB04150.1 - 0.014 15.9 0.0 0.024 15.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.11 EGB04150.1 - 0.014 15.3 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 EGB04150.1 - 0.16 11.3 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Sugar_tr PF00083.24 EGB04152.1 - 3.5e-37 128.4 5.1 3.6e-17 62.4 9.6 3.2 2 1 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EGB04152.1 - 1.2e-14 54.0 18.5 1.2e-14 54.0 18.5 3.5 3 1 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGB04152.1 - 0.00041 19.0 1.8 0.00041 19.0 1.8 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 EGB04152.1 - 0.0051 15.3 1.5 0.0076 14.7 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 EGB04152.1 - 0.16 10.8 2.2 0.11 11.4 0.2 1.6 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM Ank_2 PF12796.7 EGB04153.1 - 1.5e-23 83.2 0.0 5.8e-15 55.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB04153.1 - 3.5e-17 62.5 3.3 4.9e-08 33.4 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB04153.1 - 3.8e-13 48.3 0.1 0.00048 20.4 0.0 3.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGB04153.1 - 4.6e-13 49.0 0.5 1.4e-06 28.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB04153.1 - 9.5e-12 44.9 2.0 1.3e-06 28.6 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Histone_H2A_C PF16211.5 EGB04154.1 - 7.9e-21 73.5 1.4 2.2e-20 72.1 1.4 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB04154.1 - 1e-11 45.3 0.0 1.2e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB04154.1 - 0.0015 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB04155.1 - 6.1e-53 178.7 1.1 6.8e-53 178.5 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGB04155.1 - 0.00076 20.1 3.0 0.00098 19.7 3.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGB04155.1 - 0.00088 19.4 0.3 0.0014 18.7 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB04155.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGB04155.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGB04155.1 - 0.032 14.3 0.1 0.057 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone_H2A_C PF16211.5 EGB04156.1 - 7.9e-21 73.5 1.4 2.2e-20 72.1 1.4 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB04156.1 - 1e-11 45.3 0.0 1.2e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB04156.1 - 0.0015 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MFS_1 PF07690.16 EGB04157.1 - 1.6e-13 50.3 41.0 1.6e-13 50.3 41.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 EGB04158.1 - 6.4e-24 84.7 0.0 5.6e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB04158.1 - 4.4e-11 42.6 0.0 6.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB04158.1 - 5.8e-09 36.4 0.0 0.0027 18.2 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB04158.1 - 3.8e-06 26.7 0.0 0.056 13.0 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGB04158.1 - 1.5e-05 25.1 0.0 6.8e-05 23.0 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGB04158.1 - 2e-05 24.0 0.2 8.7e-05 21.9 0.0 2.2 4 0 0 4 4 4 1 FAD binding domain FAD_binding_2 PF00890.24 EGB04158.1 - 0.00025 20.3 0.6 0.0017 17.5 0.8 2.0 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGB04158.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EGB04158.1 - 0.023 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.6 EGB04158.1 - 0.043 14.3 0.0 7.3 7.1 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain K_oxygenase PF13434.6 EGB04158.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EGB04158.1 - 0.13 11.3 0.1 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EGB04158.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Mito_carr PF00153.27 EGB04160.1 - 4.9e-54 180.2 1.8 1.5e-17 63.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sel1 PF08238.12 EGB04161.1 - 1.6e-12 47.6 10.9 2.2e-08 34.5 1.1 3.5 3 1 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.6 EGB04161.1 - 0.061 14.0 7.1 0.095 13.4 4.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB04161.1 - 0.081 12.8 3.8 0.22 11.5 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat LSM PF01423.22 EGB04162.1 - 1.3e-20 72.8 0.0 1.5e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain zf-CCHC_6 PF15288.6 EGB04164.1 - 1.6e-06 27.8 0.1 2.7e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGB04164.1 - 0.29 11.3 2.2 0.44 10.7 0.5 1.9 2 0 0 2 2 2 0 Zinc knuckle Histone PF00125.24 EGB04165.1 - 5.3e-19 68.9 0.4 6.3e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB04165.1 - 1.9e-05 24.8 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB04165.1 - 0.0038 17.7 0.0 0.0059 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB04165.1 - 0.053 13.6 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein Peptidase_C1 PF00112.23 EGB04166.1 - 2e-51 175.2 2.0 2.7e-51 174.7 2.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB04166.1 - 0.17 10.6 5.8 0.12 11.1 1.0 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Histone PF00125.24 EGB04167.1 - 1.3e-10 41.8 0.0 1.5e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB04167.1 - 0.0014 18.9 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 EGB04167.1 - 0.076 13.0 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 YscO-like protein CENP-T_C PF15511.6 EGB04168.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB04168.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB04168.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB04168.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB04168.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB04168.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB04168.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGB04168.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Aldo_ket_red PF00248.21 EGB04169.1 - 2.7e-40 138.4 0.0 5.4e-40 137.4 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Metallophos PF00149.28 EGB04170.1 - 5.1e-15 56.5 0.0 5.6e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3523 PF12037.8 EGB04171.1 - 5.6e-67 225.9 20.4 1e-66 225.1 20.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 EGB04171.1 - 1.1e-20 74.3 0.0 4.9e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGB04171.1 - 5.1e-06 26.7 0.0 5.1e-06 26.7 0.0 2.8 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 EGB04171.1 - 7.5e-05 22.2 0.1 0.00035 20.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EGB04171.1 - 0.00015 21.5 0.0 0.00093 19.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB04171.1 - 0.0002 21.6 9.2 0.012 15.9 0.0 3.9 3 2 1 4 4 4 2 AAA domain AAA_16 PF13191.6 EGB04171.1 - 0.00036 21.0 7.2 0.0011 19.4 0.4 3.3 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EGB04171.1 - 0.0024 17.8 0.0 0.011 15.6 0.0 2.2 3 0 0 3 3 2 1 NACHT domain AAA_5 PF07728.14 EGB04171.1 - 0.0028 17.6 3.3 0.0032 17.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGB04171.1 - 0.0066 17.0 5.3 0.084 13.4 0.0 3.7 3 2 0 4 4 3 1 AAA domain ATPase PF06745.13 EGB04171.1 - 0.0088 15.4 0.0 0.1 11.9 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 EGB04171.1 - 0.01 15.6 0.1 0.03 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 EGB04171.1 - 0.019 15.2 3.7 0.019 15.2 3.7 2.4 1 1 1 2 2 1 0 TATA element modulatory factor 1 TATA binding Zot PF05707.12 EGB04171.1 - 0.026 14.2 0.1 0.68 9.5 0.0 2.5 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_3 PF07726.11 EGB04171.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EGB04171.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 EGB04171.1 - 0.045 13.8 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EGB04171.1 - 0.047 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EGB04171.1 - 0.059 13.8 0.1 0.25 11.8 0.0 2.1 3 0 0 3 3 1 0 RNA helicase AAA_25 PF13481.6 EGB04171.1 - 0.067 12.8 0.1 0.067 12.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGB04171.1 - 0.069 12.9 12.9 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGB04171.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 EGB04171.1 - 6.9 7.1 6.9 0.61 10.5 0.1 2.9 2 2 1 3 3 3 0 AAA domain Pkinase PF00069.25 EGB04172.1 - 3.9e-44 151.0 0.0 1.4e-37 129.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04172.1 - 4e-22 78.7 0.0 8.1e-22 77.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB04172.1 - 0.01 14.7 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EGB04172.1 - 0.034 13.2 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EGB04172.1 - 0.049 12.9 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGB04172.1 - 0.25 11.2 1.3 1 9.3 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGB04173.1 - 3.3e-66 223.4 0.0 4e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04173.1 - 1.2e-42 146.0 0.0 1.7e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04173.1 - 2.8e-08 33.4 0.0 1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB04173.1 - 3.3e-07 29.4 0.0 6.6e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB04173.1 - 0.00022 21.2 0.0 0.03 14.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB04173.1 - 0.0027 17.1 0.1 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGB04173.1 - 0.026 13.6 0.3 0.07 12.2 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EGB04173.1 - 0.19 10.7 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HEAT_EZ PF13513.6 EGB04174.1 - 2.7e-14 53.3 9.0 1.4e-08 35.0 0.0 7.4 5 2 2 7 7 7 2 HEAT-like repeat HEAT PF02985.22 EGB04174.1 - 3.2e-11 42.5 19.8 0.0015 18.6 0.0 9.7 11 1 0 11 11 11 3 HEAT repeat IBN_N PF03810.19 EGB04174.1 - 1.1e-09 38.1 0.6 3.4e-08 33.3 0.3 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EGB04174.1 - 7.2e-07 29.0 4.0 0.00039 20.0 0.1 4.4 5 1 0 5 5 5 2 CLASP N terminal HEAT_2 PF13646.6 EGB04174.1 - 2.3e-06 27.9 10.1 0.055 13.9 0.3 6.8 2 2 6 8 8 8 2 HEAT repeats Arm PF00514.23 EGB04174.1 - 0.00034 20.5 0.4 0.14 12.3 0.1 3.6 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGB04174.1 - 0.00035 20.6 0.9 0.064 13.3 0.0 4.0 2 2 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGB04174.1 - 0.00082 19.9 2.3 0.17 12.5 0.2 4.7 3 2 2 5 5 5 1 Vacuolar 14 Fab1-binding region DUF3830 PF12903.7 EGB04174.1 - 0.084 12.6 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) WD40 PF00400.32 EGB04175.1 - 1.8e-07 31.7 5.6 0.076 13.9 0.1 6.3 5 0 0 5 5 5 3 WD domain, G-beta repeat EF-hand_7 PF13499.6 EGB04176.1 - 4e-09 36.8 0.3 1e-07 32.3 0.3 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB04176.1 - 3.9e-08 32.3 0.2 0.002 17.5 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB04176.1 - 2.9e-06 26.7 0.3 0.11 12.5 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB04176.1 - 0.00018 20.9 0.0 0.071 12.6 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB04176.1 - 0.00019 21.2 0.1 0.0009 19.0 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain pair IQ PF00612.27 EGB04176.1 - 0.02 14.6 7.8 1.9 8.5 0.6 4.7 3 0 0 3 3 3 0 IQ calmodulin-binding motif LPD1 PF18796.1 EGB04176.1 - 0.039 14.1 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 1 ChaB PF06150.12 EGB04176.1 - 1 10.0 8.7 22 5.7 4.5 3.1 2 1 0 2 2 2 0 ChaB CC2D2AN-C2 PF15625.6 EGB04177.1 - 8.4e-16 58.2 0.0 1.7e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain Prp19 PF08606.11 EGB04178.1 - 3.2e-32 110.3 0.7 5.8e-32 109.5 0.7 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EGB04178.1 - 6.6e-16 58.4 6.5 1.4e-09 38.4 0.1 5.9 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04178.1 - 8.5e-07 29.2 0.0 0.011 16.0 0.0 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 EGB04178.1 - 1.3e-06 28.1 0.2 6.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EGB04178.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain Cytochrom_D1 PF02239.16 EGB04178.1 - 0.086 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGB04178.1 - 0.11 11.5 0.4 0.78 8.6 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 EGB04178.1 - 0.16 11.5 0.1 1.9 8.0 0.0 2.7 3 1 1 4 4 4 0 Hermansky-Pudlak syndrome 3 PDCD9 PF07147.12 EGB04178.1 - 0.17 11.1 0.1 0.24 10.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) SNF2_N PF00176.23 EGB04179.1 - 5.9e-49 166.6 0.1 8.2e-49 166.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB04179.1 - 1.1e-19 70.8 0.0 3.2e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB04179.1 - 7e-07 29.4 0.0 4.3e-06 26.8 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGB04179.1 - 0.00011 21.5 0.0 0.00023 20.4 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EGB04179.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF374 PF04028.13 EGB04179.1 - 0.085 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Myb_DNA-binding PF00249.31 EGB04180.1 - 1.4e-29 102.0 0.5 1.3e-14 54.1 0.0 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB04180.1 - 8.3e-25 86.8 0.0 1.3e-15 57.3 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGB04180.1 - 0.016 15.5 0.1 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PriCT_2 PF08707.11 EGB04180.1 - 0.033 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) Myb_DNA-bind_7 PF15963.5 EGB04180.1 - 0.034 14.0 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EGB04180.1 - 0.066 13.6 2.2 0.35 11.3 0.4 2.6 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain SRP19 PF01922.17 EGB04183.1 - 1.7e-23 83.3 0.0 1.9e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 SRP19 protein PAH PF02671.21 EGB04184.1 - 8e-41 137.9 11.3 4.2e-20 71.6 3.3 4.1 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EGB04184.1 - 2.7e-33 113.9 0.0 8.6e-33 112.3 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 EGB04184.1 - 1.4e-19 70.9 1.9 1.4e-19 70.9 1.9 3.6 4 1 0 4 4 4 1 C-terminal domain of Sin3a protein CHASE3 PF05227.13 EGB04184.1 - 0.035 14.0 0.4 0.091 12.7 0.4 1.7 1 0 0 1 1 1 0 CHASE3 domain DUF1722 PF08349.11 EGB04184.1 - 0.21 11.9 1.4 22 5.3 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) TPR_19 PF14559.6 EGB04185.1 - 1.8e-35 121.3 53.7 4.2e-05 24.0 0.1 12.7 9 3 2 12 12 12 9 Tetratricopeptide repeat TPR_14 PF13428.6 EGB04185.1 - 3e-17 61.8 56.1 0.29 12.1 2.1 16.6 10 5 7 17 17 16 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGB04185.1 - 7.2e-14 50.7 67.0 0.0018 18.3 0.6 16.5 17 0 0 17 17 17 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB04185.1 - 4.1e-13 49.3 30.2 0.011 16.0 0.1 9.0 7 1 1 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGB04185.1 - 8.9e-11 42.3 51.7 0.34 11.6 0.6 12.4 11 2 3 14 14 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB04185.1 - 3.2e-10 39.4 46.4 0.0048 17.0 0.2 13.9 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04185.1 - 5.7e-08 32.3 61.2 0.00017 21.3 0.3 14.4 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB04185.1 - 8.7e-07 29.2 58.3 1.2 9.5 0.1 13.0 10 4 4 14 14 14 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGB04185.1 - 6.5e-05 22.5 31.3 2.5 7.9 0.0 9.7 11 1 1 12 12 11 3 TPR repeat PknG_TPR PF16918.5 EGB04185.1 - 0.0035 16.1 2.8 0.096 11.4 0.0 3.5 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGB04185.1 - 0.011 15.3 0.1 0.011 15.3 0.1 6.4 6 1 0 7 7 7 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF2379 PF09543.10 EGB04185.1 - 0.036 14.3 0.2 0.036 14.3 0.2 4.1 5 0 0 5 5 4 0 Protein of unknown function (DUF2379) TPR_6 PF13174.6 EGB04185.1 - 0.037 14.7 45.8 0.67 10.7 0.0 12.7 14 0 0 14 14 12 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB04185.1 - 0.064 13.7 17.8 6.1 7.5 0.0 8.1 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB04185.1 - 0.61 10.2 34.6 4.5 7.5 0.1 11.1 13 0 0 13 13 11 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB04185.1 - 4 7.7 24.7 0.37 11.0 0.5 6.7 6 1 0 6 6 6 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EGB04186.1 - 3.2e-31 107.3 6.1 5.2e-16 58.6 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB04186.1 - 1.3e-23 82.9 4.5 3.5e-16 59.2 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGB04186.1 - 4.1e-05 23.6 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EGB04186.1 - 0.00096 19.0 0.1 0.0025 17.7 0.0 1.7 2 0 0 2 2 2 1 Myb DNA-binding like DUF1098 PF06497.11 EGB04186.1 - 0.012 16.0 0.1 0.027 14.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) Myb_DNA-bind_4 PF13837.6 EGB04186.1 - 0.03 14.7 4.4 0.13 12.6 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Spore_III_AB PF09548.10 EGB04186.1 - 0.049 13.7 0.4 0.082 13.0 0.1 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Exo70 PF03081.15 EGB04186.1 - 0.057 12.4 0.7 0.66 9.0 0.6 2.1 1 1 0 1 1 1 0 Exo70 exocyst complex subunit Myb_DNA-bind_2 PF08914.11 EGB04186.1 - 0.71 10.1 3.3 0.7 10.1 0.2 2.3 1 1 1 2 2 2 0 Rap1 Myb domain ThiF PF00899.21 EGB04187.1 - 1.5e-55 188.3 0.1 2e-55 187.8 0.1 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGB04187.1 - 1.4e-09 38.4 0.0 2.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 EGB04187.1 - 0.00073 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 EGB04187.1 - 0.0025 17.5 0.1 0.0031 17.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase efThoc1 PF11957.8 EGB04188.1 - 6e-36 124.2 0.0 8.1e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor G-alpha PF00503.20 EGB04190.1 - 1.1e-99 334.0 5.3 2.8e-99 332.6 5.3 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGB04190.1 - 1.6e-13 50.4 2.9 1.5e-10 40.8 0.6 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB04190.1 - 0.00034 20.0 5.4 0.0031 16.9 0.8 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGB04190.1 - 0.037 14.2 1.7 4.3 7.6 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGB04190.1 - 0.043 13.6 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGB04190.1 - 0.05 13.0 0.1 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family MutL_C PF08676.11 EGB04191.1 - 4.8e-18 65.3 0.0 1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EGB04191.1 - 2.2e-16 59.6 0.0 3.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGB04191.1 - 1.4e-07 31.5 0.1 2.7e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGB04191.1 - 0.0016 18.9 0.0 0.004 17.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase efThoc1 PF11957.8 EGB04192.1 - 1.8e-27 96.2 0.0 1.8e-25 89.6 0.0 2.8 2 1 1 3 3 3 2 THO complex subunit 1 transcription elongation factor DUF4790 PF16037.5 EGB04193.1 - 0.013 16.0 1.4 0.031 14.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) RGS_DHEX PF18148.1 EGB04193.1 - 0.1 12.7 0.4 0.34 11.1 0.4 1.9 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain Pkinase PF00069.25 EGB04194.1 - 7.2e-62 209.1 0.0 8.2e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04194.1 - 3.7e-33 114.9 0.0 4.6e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04194.1 - 7.7e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB04194.1 - 0.00047 19.1 0.0 0.0009 18.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGB04194.1 - 0.069 13.1 0.3 0.14 12.1 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGB04195.1 - 9.2e-57 192.4 0.0 1.6e-56 191.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04195.1 - 2.6e-29 102.3 0.0 4.7e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DOT1 PF08123.13 EGB04196.1 - 2.2e-12 47.0 0.0 3.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Herpes_HEPA PF03324.14 EGB04198.1 - 0.072 13.6 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein TTL PF03133.15 EGB04199.1 - 2.3e-73 246.9 0.0 3e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB04199.1 - 3.9e-07 29.6 0.0 0.00031 20.1 0.0 2.8 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 EGB04199.1 - 0.00025 21.1 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EGB04199.1 - 0.0009 18.6 0.0 0.054 12.7 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGB04199.1 - 0.024 14.2 0.0 17 5.0 0.0 3.0 3 0 0 3 3 3 0 RimK-like ATP-grasp domain GPS PF01825.21 EGB04199.1 - 0.15 12.6 0.1 0.78 10.3 0.0 2.1 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif IQ PF00612.27 EGB04200.1 - 0.017 14.9 1.2 0.071 12.9 0.0 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif Sec20 PF03908.13 EGB04200.1 - 0.083 12.8 3.6 0.11 12.5 0.8 2.5 2 0 0 2 2 2 0 Sec20 AMP-binding PF00501.28 EGB04201.1 - 4.6e-29 101.3 0.0 5.9e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB04201.1 - 2.8e-09 37.8 0.0 1.8e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hydrolase_4 PF12146.8 EGB04202.1 - 5.2e-06 25.9 0.0 0.098 11.9 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGB04202.1 - 0.0032 17.0 0.0 0.0062 16.0 0.0 1.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Luteo_coat PF00894.18 EGB04202.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Luteovirus coat protein Pyr_redox_2 PF07992.14 EGB04204.1 - 2.8e-07 30.1 0.1 5.2e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB04204.1 - 0.23 10.7 0.8 8.8 5.5 1.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGB04204.1 - 0.53 10.3 2.8 5.3 7.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Adaptin_N PF01602.20 EGB04205.1 - 4.4e-54 183.9 2.7 5.7e-54 183.6 2.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGB04205.1 - 3.5e-21 75.6 0.1 6.2e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Proteasom_PSMB PF10508.9 EGB04205.1 - 0.0022 16.6 1.5 0.0052 15.3 1.5 1.5 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.7 EGB04205.1 - 0.0088 16.6 0.5 3.1 8.5 0.0 2.7 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGB04205.1 - 0.015 15.4 0.6 0.065 13.3 0.2 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGB04205.1 - 0.015 15.5 0.1 3.7 8.1 0.0 4.1 3 1 0 3 3 3 0 HEAT repeat V-ATPase_H_C PF11698.8 EGB04205.1 - 0.11 12.7 0.3 0.65 10.1 0.2 2.4 1 1 1 2 2 2 0 V-ATPase subunit H Coatomer_WDAD PF04053.14 EGB04206.1 - 4.6e-135 451.1 0.0 7e-135 450.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EGB04206.1 - 4.9e-31 106.3 8.4 8.1e-08 32.8 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04206.1 - 0.0047 17.2 0.0 4 7.8 0.1 4.9 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3751 PF12571.8 EGB04206.1 - 0.064 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Phage tail-collar fibre protein Nup160 PF11715.8 EGB04206.1 - 0.32 9.6 1.8 4.8 5.7 0.0 3.1 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Chloroa_b-bind PF00504.21 EGB04207.1 - 2.8e-34 119.0 0.1 4.1e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Cullin PF00888.22 EGB04208.1 - 1.5e-136 456.5 8.7 1.8e-136 456.3 8.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGB04208.1 - 5.5e-18 64.8 1.8 1.4e-17 63.5 0.2 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF5617 PF18493.1 EGB04208.1 - 0.016 15.3 0.3 0.096 12.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) Not3 PF04065.15 EGB04208.1 - 0.017 14.5 0.7 0.13 11.7 0.0 2.6 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Cys_rich_FGFR PF00839.17 EGB04208.1 - 0.078 13.2 2.8 6 7.1 0.0 3.5 4 0 0 4 4 4 0 Cysteine rich repeat Chloroa_b-bind PF00504.21 EGB04209.1 - 1.7e-30 106.7 0.3 2.1e-30 106.4 0.3 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein MORN PF02493.20 EGB04210.1 - 1.6e-28 96.8 36.4 8.4e-07 28.5 1.8 6.9 7 0 0 7 7 7 6 MORN repeat AAA PF00004.29 EGB04212.1 - 2.3e-38 131.6 0.0 3e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGB04212.1 - 1.3e-05 25.2 0.0 4.6e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGB04212.1 - 1.6e-05 24.7 0.0 0.00011 22.0 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGB04212.1 - 0.001 19.4 0.1 0.0031 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_3 PF17862.1 EGB04212.1 - 0.0077 16.0 0.6 0.018 14.8 0.6 1.7 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 EGB04212.1 - 0.012 15.0 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGB04212.1 - 0.028 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EGB04212.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EGB04212.1 - 0.07 13.2 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EGB04212.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGB04212.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_3 PF07726.11 EGB04212.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB04212.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase BTB_2 PF02214.22 EGB04213.1 - 3.6e-08 33.7 0.0 9.9e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Phage_Gp19 PF09355.10 EGB04213.1 - 0.055 13.9 0.0 0.091 13.2 0.0 1.2 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 LRR_4 PF12799.7 EGB04214.1 - 3.3e-22 78.2 12.7 8.9e-06 26.0 0.4 4.5 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB04214.1 - 2.2e-17 63.1 4.3 1.9e-11 43.8 0.3 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EGB04214.1 - 2.6e-15 55.9 15.9 4.4e-05 23.2 2.9 4.4 2 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 EGB04214.1 - 0.27 11.9 18.9 9.8 7.2 0.1 6.9 6 2 1 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 EGB04214.1 - 1 9.6 11.3 24 5.3 0.1 6.3 8 0 0 8 8 8 0 Leucine Rich repeat MORN PF02493.20 EGB04215.1 - 9.6e-39 129.0 32.6 1.4e-05 24.7 0.1 9.7 9 0 0 9 9 9 8 MORN repeat ThiF PF00899.21 EGB04216.1 - 6.8e-56 189.4 0.0 9.3e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGB04216.1 - 1.9e-11 44.4 0.0 3.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 EGB04216.1 - 0.0065 16.5 0.0 0.021 14.9 0.0 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGB04216.1 - 0.021 15.1 0.1 0.061 13.6 0.1 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 EGB04216.1 - 0.024 14.3 0.1 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Abhydrolase_2 PF02230.16 EGB04217.1 - 2e-44 152.0 0.0 2.4e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EGB04217.1 - 4.2e-09 36.3 0.0 7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EGB04217.1 - 1.8e-05 24.7 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB04217.1 - 4.6e-05 23.0 0.0 0.053 13.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGB04217.1 - 7.4e-05 23.4 0.5 0.00012 22.8 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB04217.1 - 0.00058 19.2 0.3 0.18 11.0 0.2 2.5 1 1 2 3 3 3 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EGB04217.1 - 0.026 14.0 0.3 0.079 12.4 0.2 1.8 1 1 1 2 2 2 0 Esterase PHB depolymerase Esterase PF00756.20 EGB04217.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 EGB04217.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PAP2_C PF14360.6 EGB04218.1 - 2.5e-13 50.4 0.5 2.5e-13 50.4 0.5 3.1 4 0 0 4 4 4 1 PAP2 superfamily C-terminal AP2 PF00847.20 EGB04218.1 - 1.6e-10 41.0 3.8 8.2e-05 22.8 0.3 3.4 3 0 0 3 3 3 2 AP2 domain LRR_6 PF13516.6 EGB04218.1 - 0.012 15.6 0.1 2.1 8.6 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat GlcNAc PF11397.8 EGB04219.1 - 3.3e-07 30.1 0.0 4.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) CNOT11 PF10155.9 EGB04220.1 - 5.8e-53 178.3 0.7 7.5e-53 178.0 0.7 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Clat_adaptor_s PF01217.20 EGB04222.1 - 1.6e-20 73.5 0.0 2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Topoisom_I PF01028.20 EGB04223.1 - 1.1e-84 283.3 4.0 2.3e-84 282.3 4.0 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGB04223.1 - 6.5e-76 254.6 1.3 1e-75 253.9 0.0 2.0 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGB04223.1 - 1.2e-33 114.8 0.6 3.2e-33 113.5 0.6 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain KxDL PF10241.9 EGB04223.1 - 0.24 11.7 2.3 0.81 10.0 2.3 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein HR1 PF02185.16 EGB04223.1 - 1.4 9.1 8.7 4.1 7.6 1.1 3.6 3 0 0 3 3 3 0 Hr1 repeat DUF2203 PF09969.9 EGB04223.1 - 5.2 7.8 7.8 0.61 10.8 2.3 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.22 EGB04223.1 - 6.1 7.1 10.5 4.8 7.5 7.9 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MerR-DNA-bind PF09278.11 EGB04223.1 - 6.7 7.3 7.0 1.2 9.7 1.9 2.4 3 0 0 3 3 3 0 MerR, DNA binding Pkinase PF00069.25 EGB04224.1 - 5.6e-61 206.2 0.0 6.5e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04224.1 - 1.6e-38 132.5 0.0 1.8e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04224.1 - 7e-08 32.1 0.0 6.9e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB04224.1 - 3e-07 29.6 0.0 5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB04224.1 - 1.9e-05 24.7 0.0 0.015 15.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB04224.1 - 0.0022 17.4 0.1 0.0037 16.6 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family N_formyltrans_C PF18216.1 EGB04224.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Seadorna_VP7 PF07387.11 EGB04224.1 - 0.023 13.7 0.1 0.05 12.7 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EGB04224.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TRAPPC9-Trs120 PF08626.11 EGB04225.1 - 0.022 12.1 0.0 0.98 6.7 0.0 2.5 3 0 0 3 3 3 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit MT PF12777.7 EGB04226.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor PP2C PF00481.21 EGB04227.1 - 3.1e-14 53.2 0.0 4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C TctA PF01970.16 EGB04228.1 - 0.027 13.2 13.6 0.25 10.0 1.5 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family HTH_36 PF13730.6 EGB04228.1 - 3.1 7.8 6.9 32 4.6 0.5 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain Lipase_GDSL_2 PF13472.6 EGB04229.1 - 0.013 15.9 0.2 0.025 15.0 0.2 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GlnE PF03710.15 EGB04229.1 - 0.068 12.6 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase DUF687 PF05095.12 EGB04229.1 - 0.082 11.4 0.3 0.13 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Ribosomal_L10 PF00466.20 EGB04230.1 - 1e-21 76.9 0.0 1.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGB04230.1 - 1e-12 47.9 0.4 2.4e-12 46.7 0.1 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Clat_adaptor_s PF01217.20 EGB04231.1 - 2e-17 63.4 0.1 2.5e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 EGB04232.1 - 3.6e-28 98.7 0.0 4e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04232.1 - 1.8e-18 66.8 0.0 2.2e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB04232.1 - 0.001 19.0 1.0 0.2 11.6 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB04232.1 - 0.0039 16.6 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arylsulfotrans PF05935.11 EGB04234.1 - 2.6e-05 23.3 0.0 0.00048 19.2 0.0 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Dysbindin PF04440.16 EGB04236.1 - 0.02 15.1 3.2 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) APG6 PF04111.12 EGB04238.1 - 1.6e-23 83.6 0.4 1.2e-22 80.8 0.0 2.3 2 0 0 2 2 2 1 Apg6 BARA domain TPR_12 PF13424.6 EGB04238.1 - 1.2e-08 35.1 9.3 0.00094 19.4 3.8 6.8 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB04238.1 - 2e-07 31.4 12.3 0.0045 17.5 2.5 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB04238.1 - 2.2e-05 24.2 23.2 0.2 11.8 1.9 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB04238.1 - 3.8e-05 23.4 2.0 4 7.7 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB04238.1 - 0.032 14.5 6.4 1.2 9.4 3.7 3.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EGB04238.1 - 0.051 13.9 2.1 0.7 10.3 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat PocR PF10114.9 EGB04238.1 - 0.059 13.1 0.1 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 Sensory domain found in PocR TPR_1 PF00515.28 EGB04238.1 - 0.15 12.0 24.4 0.072 12.9 2.1 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB04238.1 - 0.22 12.0 4.6 3.8 8.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_a_NII PF11490.8 EGB04238.1 - 0.79 9.6 3.9 0.48 10.3 0.1 2.6 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II TPR_6 PF13174.6 EGB04238.1 - 2 9.2 14.7 0.29 11.9 0.4 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB04238.1 - 3.9 7.9 16.0 27 5.3 1.5 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Rubrerythrin PF02915.17 EGB04238.1 - 5.5 7.4 8.2 11 6.4 2.5 3.5 3 1 2 5 5 4 0 Rubrerythrin Glyco_trans_1_2 PF13524.6 EGB04239.1 - 6.9e-06 26.4 0.2 2.8e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pkinase PF00069.25 EGB04240.1 - 6.7e-60 202.7 0.0 1.1e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04240.1 - 4e-31 108.3 0.0 6e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04240.1 - 2.4e-06 27.1 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB04240.1 - 5.3e-06 26.5 3.3 9.5e-06 25.7 0.1 2.6 2 2 2 4 4 4 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB04240.1 - 0.0087 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YukC PF10140.9 EGB04240.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 EGB04240.1 - 0.14 11.0 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DOCK-C2 PF14429.6 EGB04241.1 - 5.4e-22 78.6 0.0 9.4e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins RhoGEF PF00621.20 EGB04241.1 - 7.7e-17 62.1 0.0 1.5e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain zf-C3HC4_3 PF13920.6 EGB04241.1 - 6.4e-12 45.1 7.7 2e-11 43.6 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB04241.1 - 6.5e-05 22.7 7.4 0.00018 21.3 7.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DOCK_N PF16172.5 EGB04241.1 - 0.00055 19.0 0.0 0.00087 18.3 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus zf-RING_2 PF13639.6 EGB04241.1 - 0.0064 16.8 8.7 0.023 15.0 8.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB04241.1 - 0.042 13.7 8.6 0.13 12.1 8.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 EGB04242.1 - 4.7e-09 36.7 1.5 0.0018 19.1 0.0 5.0 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04242.1 - 1e-08 35.3 0.1 0.37 11.1 0.0 5.9 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EGB04242.1 - 8.9e-07 28.9 18.1 5.2 6.9 0.0 9.1 8 2 3 11 11 11 4 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 EGB04242.1 - 9.7e-07 28.2 1.7 0.011 14.9 0.1 3.6 2 1 1 3 3 3 2 Coatomer WD associated region eIF2A PF08662.11 EGB04242.1 - 0.052 13.4 0.0 1.6 8.6 0.0 3.2 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A RGS PF00615.19 EGB04242.1 - 0.08 13.2 2.6 0.37 11.1 0.2 3.0 3 0 0 3 3 3 0 Regulator of G protein signaling domain TPR_11 PF13414.6 EGB04242.1 - 0.33 10.7 1.5 35 4.2 0.0 4.6 5 0 0 5 5 5 0 TPR repeat UPF0227 PF05728.12 EGB04242.1 - 0.55 10.1 2.5 3 7.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) TPR_7 PF13176.6 EGB04242.1 - 5.4 7.3 19.9 1.1 9.5 0.2 8.0 8 2 0 8 8 8 0 Tetratricopeptide repeat WD40 PF00400.32 EGB04243.1 - 3.2e-31 106.9 15.6 4.8e-07 30.4 0.4 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04243.1 - 9.7e-09 35.4 1.1 0.37 11.1 0.0 5.0 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB04243.1 - 6.6e-06 25.0 3.7 0.22 10.2 0.0 4.7 3 1 0 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGB04243.1 - 6.6e-05 21.6 0.0 0.047 12.2 0.1 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGB04243.1 - 0.00013 21.0 1.4 5.3 5.9 0.0 4.2 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGB04243.1 - 0.00022 20.1 0.1 0.044 12.5 0.0 3.3 2 1 2 4 4 4 1 Nup133 N terminal like Lactonase PF10282.9 EGB04243.1 - 0.011 15.0 0.0 0.36 10.0 0.0 2.1 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller PRD_Mga PF08270.11 EGB04244.1 - 0.088 12.5 1.7 3.1 7.4 0.5 2.5 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) PRD domain Pkinase PF00069.25 EGB04245.1 - 2.5e-68 230.3 0.0 3e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04245.1 - 9.2e-37 126.7 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04245.1 - 9.7e-06 25.1 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGB04245.1 - 0.00024 20.2 0.6 0.00035 19.6 0.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain CENP-B_N PF04218.13 EGB04245.1 - 0.25 11.0 0.9 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain AAA_6 PF12774.7 EGB04246.1 - 3e-155 516.1 0.0 2.6e-154 513.1 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB04246.1 - 8.9e-127 423.5 1.7 3e-126 421.7 0.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGB04246.1 - 8.7e-98 327.3 0.0 1.2e-96 323.5 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGB04246.1 - 1.3e-93 313.1 0.0 2.6e-93 312.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGB04246.1 - 7.3e-90 299.9 1.7 5.2e-88 293.9 0.4 2.9 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGB04246.1 - 6.2e-70 234.4 0.0 1.2e-68 230.2 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB04246.1 - 6.4e-55 185.4 0.0 1.5e-54 184.2 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB04246.1 - 1e-44 151.4 0.0 5.7e-42 142.6 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGB04246.1 - 8e-42 143.5 8.2 8e-42 143.5 8.2 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EGB04246.1 - 6e-29 100.7 0.0 1.7e-28 99.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGB04246.1 - 1.1e-14 54.4 0.0 5.6e-14 52.2 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB04246.1 - 1.3e-09 38.1 0.0 0.062 13.3 0.0 5.4 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EGB04246.1 - 8.6e-06 26.2 0.1 0.48 10.8 0.0 3.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB04246.1 - 0.0042 17.5 0.0 7 7.1 0.0 3.6 3 1 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 EGB04246.1 - 0.011 16.3 0.1 7.8 7.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EGB04246.1 - 0.024 15.0 0.0 14 6.0 0.0 4.2 4 0 0 4 4 3 0 AAA ATPase domain AAA_22 PF13401.6 EGB04246.1 - 0.044 14.1 0.2 2.5 8.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EGB04246.1 - 0.13 11.9 0.4 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain tRNA_bind_3 PF17176.4 EGB04246.1 - 0.45 10.8 3.0 1.4 9.2 3.0 1.8 1 0 0 1 1 1 0 tRNA-binding domain IFT57 PF10498.9 EGB04246.1 - 0.84 8.5 7.0 0.25 10.3 1.0 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 APG6_N PF17675.1 EGB04246.1 - 1.9 9.0 25.4 0.037 14.6 5.8 3.3 3 0 0 3 3 2 0 Apg6 coiled-coil region Spc7 PF08317.11 EGB04246.1 - 2.2 7.1 27.6 0.057 12.3 4.5 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein DHR10 PF18595.1 EGB04246.1 - 2.3 8.3 18.5 0.12 12.5 4.3 2.9 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Exonuc_VII_L PF02601.15 EGB04246.1 - 2.3 7.7 8.0 12 5.4 2.0 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF5082 PF16888.5 EGB04246.1 - 3.6 7.9 11.6 6.1 7.1 1.4 3.4 3 0 0 3 3 2 0 Domain of unknown function (DUF5082) Adap_comp_sub PF00928.21 EGB04247.1 - 1.5e-63 214.7 0.0 1.8e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGB04247.1 - 4.1e-05 23.5 0.0 6.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain QH-AmDH_gamma PF08992.11 EGB04248.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit RNA_pol_Rpb2_6 PF00562.28 EGB04249.1 - 2.4e-93 313.3 0.0 1.7e-92 310.5 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 EGB04249.1 - 1e-26 92.9 0.0 2e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 EGB04249.1 - 5.5e-26 91.3 0.0 8.8e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGB04249.1 - 2.6e-15 56.6 0.0 6.2e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 EGB04249.1 - 1.3e-10 41.1 0.0 3.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 EGB04249.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Dynein_light PF01221.18 EGB04252.1 - 8.8e-20 70.8 0.2 9.5e-20 70.7 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 WD40 PF00400.32 EGB04253.1 - 4.5e-12 46.3 5.9 0.00047 20.9 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04253.1 - 0.0027 18.0 0.0 25 5.3 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB04253.1 - 0.11 11.5 0.0 1.1 8.1 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB04253.1 - 0.13 12.2 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 EGB04253.1 - 0.15 12.6 1.1 1.1 9.9 0.0 3.0 3 1 0 3 3 3 0 PQQ-like domain B9-C2 PF07162.11 EGB04254.1 - 1.2e-28 100.4 0.1 1.4e-28 100.3 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ank_2 PF12796.7 EGB04255.1 - 5.5e-16 58.9 1.3 9.9e-12 45.3 2.2 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB04255.1 - 7.2e-12 45.6 0.5 1e-06 29.2 0.6 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB04255.1 - 1.7e-10 40.2 5.3 0.036 14.6 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EGB04255.1 - 2.6e-10 40.4 1.2 0.00077 19.7 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB04255.1 - 1.1e-07 31.9 13.5 0.0045 17.4 1.6 3.9 2 1 1 3 3 3 3 Ankyrin repeat Ribosomal_L5 PF00281.19 EGB04256.1 - 7.5e-19 67.8 0.0 2e-18 66.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 EGB04256.1 - 5.6e-18 64.9 0.0 1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus HTH_ABP1_N PF18107.1 EGB04256.1 - 0.12 12.1 0.2 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain EF1G PF00647.19 EGB04257.1 - 1.3e-36 124.9 0.4 2.4e-36 124.0 0.4 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGB04257.1 - 3.6e-16 59.3 0.0 8.2e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB04257.1 - 2.5e-12 46.8 0.9 4e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB04257.1 - 1.3e-09 38.0 0.5 3.1e-09 36.7 0.5 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB04257.1 - 3.8e-09 36.8 0.0 9.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB04257.1 - 3.1e-07 30.6 0.0 6.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB04257.1 - 3e-06 27.3 0.0 9e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 EGB04257.1 - 0.00062 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGB04257.1 - 0.16 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Kinesin PF00225.23 EGB04258.1 - 2e-42 145.3 0.0 2.3e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB04258.1 - 2.8e-23 82.5 0.0 3.3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding DUF927 PF06048.11 EGB04258.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF927) DUF720 PF05302.11 EGB04259.1 - 4.3 7.2 7.1 21 4.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF720) SURNod19 PF07712.12 EGB04260.1 - 1.1e-14 54.0 0.2 2.4e-12 46.3 0.0 2.8 3 0 0 3 3 3 2 Stress up-regulated Nod 19 Snapin_Pallidin PF14712.6 EGB04261.1 - 0.15 12.5 0.2 0.15 12.5 0.2 3.6 3 1 1 4 4 4 0 Snapin/Pallidin FUSC-like PF12805.7 EGB04261.1 - 0.17 10.9 2.2 0.34 9.9 1.8 1.7 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS zf-C4H2 PF10146.9 EGB04261.1 - 0.25 11.6 12.0 0.39 11.0 12.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein CRT10 PF08728.10 EGB04261.1 - 1.4 7.0 8.2 1.6 6.8 8.2 1.0 1 0 0 1 1 1 0 CRT10 Matrilin_ccoil PF10393.9 EGB04261.1 - 1.6 8.7 5.5 18 5.3 0.1 3.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin V_ATPase_I PF01496.19 EGB04261.1 - 3.1 5.6 10.5 4 5.2 10.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 EGB04261.1 - 8.8 6.4 9.4 1.8 8.6 1.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Med9 PF07544.13 EGB04261.1 - 9 6.5 11.5 14 5.8 4.8 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DNA_methylase PF00145.17 EGB04263.1 - 0.0002 20.8 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Trypan_PARP PF05887.11 EGB04263.1 - 0.0011 18.9 25.5 0.0011 18.9 25.5 3.8 4 0 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) TIL PF01826.17 EGB04263.1 - 2.4 8.5 32.2 0.46 10.8 7.0 3.1 2 1 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain C_tripleX PF02363.19 EGB04263.1 - 3.1 8.3 15.8 8.5 6.9 5.2 3.6 1 1 1 2 2 2 0 Cysteine rich repeat HATPase_c_2 PF13581.6 EGB04263.1 - 3.9 7.5 5.0 13 5.8 5.0 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain cNMP_binding PF00027.29 EGB04267.1 - 2.2e-16 59.7 0.2 3.7e-07 30.1 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Methyltransf_31 PF13847.6 EGB04269.1 - 1.9e-06 27.8 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB04269.1 - 0.00011 22.8 0.0 0.00042 21.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGB04269.1 - 0.0018 18.3 0.1 0.0038 17.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGB04269.1 - 0.012 15.1 0.0 0.069 12.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EGB04269.1 - 0.024 14.0 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGB04269.1 - 0.034 14.0 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB04269.1 - 0.1 13.4 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 EGB04269.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase SSFA2_C PF14723.6 EGB04270.1 - 0.014 15.3 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Cys_Knot_tox PF17486.2 EGB04270.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Cystine knot toxins Ketoacyl-synt_C PF02801.22 EGB04271.1 - 1.3e-08 34.8 0.5 3.4e-08 33.5 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HMG_box PF00505.19 EGB04271.1 - 0.00028 21.2 2.5 0.00063 20.1 2.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB04271.1 - 0.0072 16.9 1.7 0.023 15.3 1.7 1.9 1 0 0 1 1 1 1 HMG-box domain Cwf_Cwc_15 PF04889.12 EGB04271.1 - 0.0078 16.0 14.5 0.0078 16.0 14.5 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein PYC_OADA PF02436.18 EGB04271.1 - 0.017 14.9 0.3 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 Conserved carboxylase domain HMG_box_5 PF14887.6 EGB04271.1 - 0.068 13.1 0.5 0.18 11.8 0.5 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DNA_pol_phi PF04931.13 EGB04271.1 - 0.2 9.7 19.6 0.29 9.2 19.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 EGB04271.1 - 0.63 9.9 12.7 1.4 8.8 12.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 EGB04271.1 - 0.8 9.0 21.0 1.4 8.2 21.0 1.3 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 EGB04271.1 - 1.5 8.7 10.8 2.5 8.0 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 EGB04271.1 - 1.6 8.1 16.6 0.02 14.4 8.7 1.7 2 0 0 2 2 2 0 SDA1 Tom22 PF04281.13 EGB04271.1 - 2 8.2 6.2 4.4 7.1 6.2 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 GCIP PF13324.6 EGB04271.1 - 2.1 7.9 6.4 4.2 6.9 6.4 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RPA43_OB PF17875.1 EGB04271.1 - 3.5 8.3 7.1 6.9 7.3 3.4 2.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF2457 PF10446.9 EGB04271.1 - 7.4 5.6 24.6 13 4.7 24.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 EGB04271.1 - 9.1 6.5 23.1 0.43 10.8 16.9 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 ketoacyl-synt PF00109.26 EGB04272.1 - 8.1e-22 78.0 6.2 9.8e-22 77.7 6.2 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ECH_1 PF00378.20 EGB04273.1 - 6.5e-24 84.6 0.1 6.3e-10 38.8 0.0 3.3 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase PP-binding PF00550.25 EGB04273.1 - 7.2e-20 71.1 1.3 1.1e-08 35.3 0.3 4.2 2 1 1 3 3 3 2 Phosphopantetheine attachment site ECH_2 PF16113.5 EGB04273.1 - 2.1e-12 47.2 0.4 3.8e-05 23.3 0.0 3.5 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase Ketoacyl-synt_C PF02801.22 EGB04273.1 - 0.004 17.2 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EGB04273.1 - 0.12 11.8 0.5 0.32 10.4 0.2 1.9 2 0 0 2 2 2 0 Acyl transferase domain Patched PF02460.18 EGB04274.1 - 1.4e-18 66.4 18.2 1e-11 43.7 10.7 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EGB04274.1 - 6.1e-07 29.4 1.6 6.1e-07 29.4 1.6 3.4 4 0 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation GCD14 PF08704.10 EGB04275.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SDA1 PF05285.12 EGB04276.1 - 1.4 8.3 46.2 0.052 13.0 20.3 2.9 3 0 0 3 3 3 0 SDA1 DUF913 PF06025.12 EGB04276.1 - 1.9 7.4 10.1 1.3 8.0 3.4 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pkinase PF00069.25 EGB04277.1 - 4.4e-16 59.0 0.0 1.7e-08 34.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04277.1 - 1.7e-05 24.2 0.0 0.00012 21.4 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Trypan_PARP PF05887.11 EGB04278.1 - 0.0019 18.2 26.6 0.0019 18.2 26.6 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) SHOCT PF09851.9 EGB04278.1 - 0.0058 16.3 0.0 0.021 14.6 0.0 2.1 1 0 0 1 1 1 1 Short C-terminal domain WDCP PF15390.6 EGB04278.1 - 5.8 5.2 8.4 13 4.1 8.4 1.5 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family La PF05383.17 EGB04279.1 - 9.4e-05 22.4 0.0 0.72 10.0 0.0 2.6 2 0 0 2 2 2 2 La domain Prok-RING_1 PF14446.6 EGB04279.1 - 0.00014 21.7 12.3 0.067 13.1 2.4 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 HEPN_Swt1 PF18731.1 EGB04279.1 - 0.00026 21.3 0.5 0.98 9.8 0.1 2.3 2 0 0 2 2 2 2 Swt1-like HEPN DUF2180 PF09947.9 EGB04279.1 - 0.00083 19.3 10.1 0.12 12.4 0.6 3.1 3 0 0 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2180) EF-hand_6 PF13405.6 EGB04279.1 - 0.0041 16.9 0.3 6.8 6.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB04279.1 - 0.0047 16.4 0.7 6.2 6.6 0.1 3.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB04279.1 - 0.045 13.3 0.4 15 5.2 0.1 2.7 2 0 0 2 2 2 0 EF hand zf-RRPl_C4 PF17026.5 EGB04279.1 - 0.077 13.1 9.1 0.063 13.4 2.0 2.5 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Terminase_GpA PF05876.12 EGB04279.1 - 0.55 8.7 5.1 3 6.3 1.4 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-CHY PF05495.12 EGB04279.1 - 0.77 10.3 11.8 1.7 9.2 4.0 2.5 2 0 0 2 2 2 0 CHY zinc finger zinc-ribbons_6 PF07191.12 EGB04279.1 - 1 9.4 11.4 2 8.5 3.3 2.5 2 0 0 2 2 2 0 zinc-ribbons SR1P PF13790.6 EGB04279.1 - 1.4 9.1 16.5 1.6 8.9 0.9 3.6 3 0 0 3 3 3 0 SR1 protein NCD3G PF07562.14 EGB04279.1 - 7.1 6.7 10.1 20 5.3 0.7 2.8 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR AT_hook PF02178.19 EGB04280.1 - 0.0069 16.1 0.3 0.018 14.9 0.3 1.8 1 0 0 1 1 1 1 AT hook motif Abhydrolase_6 PF12697.7 EGB04281.1 - 1e-05 26.3 5.5 2e-05 25.3 5.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB04281.1 - 0.00017 21.4 0.6 0.00099 18.8 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 EGB04282.1 - 2e-24 86.6 3.8 2.3e-24 86.3 3.8 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ECH_1 PF00378.20 EGB04283.1 - 1.3e-13 50.9 0.0 1.4e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB04283.1 - 5.4e-05 22.8 0.2 5.4e-05 22.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 EGB04284.1 - 7.7e-22 78.1 2.7 8e-22 78.0 2.7 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGB04284.1 - 0.067 13.0 1.3 0.078 12.8 0.4 1.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EGB04284.1 - 0.16 11.3 0.2 0.17 11.2 0.2 1.1 1 0 0 1 1 1 0 Thiolase, N-terminal domain ECH_1 PF00378.20 EGB04285.1 - 1.8e-17 63.5 0.1 2.1e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB04285.1 - 4e-07 29.8 0.7 4.3e-07 29.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 EGB04286.1 - 4.6e-34 118.1 10.0 5.3e-34 117.9 10.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EGB04286.1 - 0.011 15.2 0.8 0.015 14.7 0.8 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain HMG_CoA_synt_N PF01154.17 EGB04287.1 - 2.5e-27 95.9 0.0 2.7e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 EGB04288.1 - 3.9e-11 43.0 0.1 4.1e-11 42.9 0.1 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HMG_CoA_synt_N PF01154.17 EGB04289.1 - 3e-27 95.6 0.1 3.2e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 EGB04291.1 - 1.4e-27 96.9 9.4 1.7e-27 96.6 9.4 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGB04291.1 - 0.54 10.1 4.2 19 5.2 4.2 2.4 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 EGB04292.1 - 3.5e-28 98.6 0.1 3.8e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_N PF01154.17 EGB04293.1 - 2e-26 92.9 0.2 2.4e-26 92.6 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EGB04293.1 - 0.24 11.0 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal ECH_1 PF00378.20 EGB04294.1 - 1.8e-13 50.4 0.0 1.9e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB04294.1 - 0.056 12.9 0.0 0.056 12.9 0.0 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGB04295.1 - 1.8e-18 66.7 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB04295.1 - 9.5e-09 35.2 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 EGB04296.1 - 1.6e-14 54.1 1.6 1.7e-14 54.0 1.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ketoacyl-synt PF00109.26 EGB04297.1 - 1.4e-25 90.3 7.2 2.6e-25 89.5 7.2 1.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB04297.1 - 6.9e-08 32.5 0.1 2e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EGB04297.1 - 0.0035 17.1 0.5 0.035 14.0 0.1 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EGB04297.1 - 0.055 12.8 0.3 0.074 12.4 0.3 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain GFO_IDH_MocA PF01408.22 EGB04298.1 - 0.051 14.4 0.0 0.076 13.8 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Patched PF02460.18 EGB04299.1 - 1.8e-17 62.7 9.2 7.1e-14 50.9 0.4 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EGB04299.1 - 1.7e-11 44.2 12.0 2.7e-10 40.3 1.0 2.3 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EGB04299.1 - 0.00074 18.5 26.8 0.086 11.8 8.8 2.7 2 1 0 2 2 2 2 MMPL family RVT_1 PF00078.27 EGB04300.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCCH PF00642.24 EGB04301.1 - 1.1e-06 28.4 3.1 2.1e-06 27.5 3.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGB04301.1 - 0.00011 22.1 1.5 0.00026 20.9 1.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGB04301.1 - 0.00017 21.3 1.0 0.00034 20.3 1.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger KRTAP PF11759.8 EGB04302.1 - 0.00032 21.2 63.3 1.8e+04 -24.0 63.3 3.6 1 1 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 EGB04302.1 - 2.7 8.1 67.6 3.6e+03 -2.0 0.4 4.0 2 1 0 2 2 2 0 Keratin type II head XRN1_DBM PF18245.1 EGB04303.1 - 0.0015 18.4 0.1 4.7 7.3 0.0 3.1 2 0 0 2 2 2 2 5-3 exonuclease XRN1 DCP1-binding motif zf-C2HE PF16278.5 EGB04303.1 - 0.044 14.2 1.1 31 5.1 0.0 3.8 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger HscB_4_cys PF18256.1 EGB04303.1 - 0.11 12.3 5.2 5.8 6.8 0.5 2.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif FAP PF07174.11 EGB04305.1 - 7.3 6.0 25.9 11 5.4 25.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Mucin PF01456.17 EGB04306.1 - 0.5 10.4 7.5 0.2 11.6 0.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein C1_1 PF00130.22 EGB04307.1 - 0.0083 16.0 0.3 0.016 15.1 0.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 EGB04307.1 - 0.063 13.3 2.7 0.079 13.0 1.0 2.0 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 EGB04307.1 - 0.094 12.6 4.7 0.17 11.8 4.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 EGB04307.1 - 0.39 10.3 2.0 0.75 9.4 2.0 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF134 PF02001.16 EGB04307.1 - 0.83 10.2 3.0 1.8 9.2 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF134 DivIC PF04977.15 EGB04307.1 - 0.88 9.4 3.2 2.5 7.9 3.2 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 EGB04307.1 - 1.5 8.1 8.7 0.098 12.0 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) p47_phox_C PF08944.11 EGB04309.1 - 0.069 12.6 1.7 0.19 11.2 1.7 1.8 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain TIP49 PF06068.13 EGB04312.1 - 6.9e-169 561.6 0.1 8.5e-169 561.3 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGB04312.1 - 5.4e-23 80.9 0.2 1.6e-22 79.4 0.2 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGB04312.1 - 3.1e-10 40.6 0.0 2.7e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGB04312.1 - 1.6e-09 37.7 0.3 2.2e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB04312.1 - 6.2e-07 29.8 0.0 0.038 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGB04312.1 - 7.8e-05 23.1 0.1 0.0006 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGB04312.1 - 0.00076 19.5 0.1 0.046 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGB04312.1 - 0.0014 18.9 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGB04312.1 - 0.0019 17.7 0.3 0.055 12.9 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGB04312.1 - 0.0045 17.3 1.3 0.087 13.2 1.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB04312.1 - 0.0052 16.4 0.1 0.0095 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGB04312.1 - 0.006 16.3 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain DnaB_C PF03796.15 EGB04312.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 EGB04312.1 - 0.017 14.4 0.2 0.034 13.4 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EGB04312.1 - 0.027 15.0 0.0 0.078 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB04312.1 - 0.036 14.2 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 EGB04312.1 - 0.045 12.4 0.1 0.36 9.4 0.0 2.0 2 0 0 2 2 2 0 GvpD gas vesicle protein IstB_IS21 PF01695.17 EGB04312.1 - 0.05 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 EGB04312.1 - 0.061 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGB04312.1 - 0.073 13.1 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EGB04312.1 - 0.1 12.6 0.1 0.27 11.2 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGB04312.1 - 0.19 11.2 0.1 0.7 9.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3039 PF11238.8 EGB04316.1 - 0.01 15.6 0.2 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) Toxin_17 PF08086.11 EGB04316.1 - 0.034 14.4 0.2 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Ergtoxin family GPS2_interact PF15784.5 EGB04316.1 - 0.037 14.5 0.0 0.082 13.3 0.0 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Toxin_trans PF07952.12 EGB04316.1 - 0.075 12.1 0.0 12 4.8 0.0 2.2 2 0 0 2 2 2 0 Clostridium neurotoxin, Translocation domain GHD PF17834.1 EGB04316.1 - 0.1 12.7 0.3 26 5.0 0.0 2.5 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase MreD PF04093.12 EGB04316.1 - 0.1 12.6 8.8 2.9 7.9 1.2 2.9 2 0 0 2 2 2 0 rod shape-determining protein MreD NPC1_N PF16414.5 EGB04316.1 - 0.13 11.8 0.2 18 4.8 0.1 2.2 2 0 0 2 2 2 0 Niemann-Pick C1 N terminus Prenyltrans PF00432.21 EGB04318.1 - 0.072 12.8 1.4 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat ABC2_membrane PF01061.24 EGB04319.1 - 0.21 10.9 8.6 0.24 10.8 3.6 2.5 2 1 1 3 3 3 0 ABC-2 type transporter Pkinase PF00069.25 EGB04320.1 - 9.1e-47 159.6 0.0 1.1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04320.1 - 7.7e-22 77.8 0.0 1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.28 EGB04322.1 - 3e-15 55.7 0.0 6.2e-15 54.7 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGB04323.1 - 1.1e-17 64.5 1.9 1.1e-17 64.4 1.9 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FSH1 PF03959.13 EGB04324.1 - 0.019 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 EGB04325.1 - 2.2e-20 73.3 8.6 3.3e-20 72.8 8.6 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB04325.1 - 4.8e-17 62.1 0.7 1.4e-16 60.6 0.7 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EGB04325.1 - 0.0019 18.0 0.3 0.0055 16.5 0.3 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ubiquitin PF00240.23 EGB04326.1 - 4.1e-24 84.1 0.2 4.4e-24 84.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB04326.1 - 1.2e-11 44.2 0.2 1.3e-11 44.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB04326.1 - 0.00012 22.5 0.0 0.00012 22.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB04326.1 - 0.00053 19.9 0.0 0.00059 19.7 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EGB04326.1 - 0.1 13.2 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SWIM PF04434.17 EGB04327.1 - 0.014 15.0 0.4 0.014 15.0 0.4 2.0 2 0 0 2 2 2 0 SWIM zinc finger ABC2_membrane PF01061.24 EGB04328.1 - 5.9e-25 87.9 22.5 5.9e-25 87.9 22.5 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGB04328.1 - 1.6e-21 77.3 0.0 2.4e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGB04328.1 - 4.8e-07 29.2 7.2 4.8e-07 29.2 7.2 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGB04328.1 - 8.9e-05 22.2 0.1 0.00022 20.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB04328.1 - 0.00043 20.2 0.1 0.6 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB04328.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EGB04328.1 - 0.0038 17.5 0.0 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGB04328.1 - 0.0087 16.6 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB04328.1 - 0.062 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGB04328.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGB04328.1 - 0.2 11.1 0.0 0.68 9.3 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain CitMHS PF03600.16 EGB04328.1 - 2.9 7.0 7.6 16 4.6 7.6 2.0 1 1 0 1 1 1 0 Citrate transporter Plant_tran PF04827.14 EGB04330.1 - 3.1e-24 85.7 0.0 5.1e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 EGB04330.1 - 8.2e-08 32.1 0.2 1.4e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3835 PF12927.7 EGB04330.1 - 0.17 12.7 1.1 0.48 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) SAP PF02037.27 EGB04331.1 - 0.012 15.3 1.5 0.026 14.3 0.3 2.1 2 0 0 2 2 2 0 SAP domain TerC PF03741.16 EGB04332.1 - 3.7e-35 121.3 0.3 6.3e-35 120.5 0.3 1.4 1 0 0 1 1 1 1 Integral membrane protein TerC family REJ PF02010.15 EGB04333.1 - 1.3e-32 113.2 0.0 1.8e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 REJ domain FH2 PF02181.23 EGB04333.1 - 1.1e-26 93.9 0.0 1.6e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 EGB04333.1 - 4.9e-14 53.0 4.3 5.1e-09 36.7 1.8 3.8 2 2 1 3 3 3 2 Subunit CCDC53 of WASH complex Laminin_G_3 PF13385.6 EGB04333.1 - 2.7e-10 40.6 0.0 1.6e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 EGB04333.1 - 0.0056 17.0 2.1 0.015 15.7 2.1 1.7 1 0 0 1 1 1 1 EGF-like domain PgaD PF13994.6 EGB04333.1 - 0.21 11.6 0.1 0.64 10.1 0.1 1.8 1 0 0 1 1 1 0 PgaD-like protein ABC1 PF03109.16 EGB04334.1 - 1.5e-20 73.5 0.0 3.7e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB04334.1 - 7.8e-06 26.0 0.2 1.8e-05 24.8 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB04334.1 - 0.076 12.6 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family JSRP PF15312.6 EGB04334.1 - 0.08 12.9 0.0 0.35 10.8 0.0 2.1 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein HTH_29 PF13551.6 EGB04334.1 - 0.12 12.4 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Pkinase PF00069.25 EGB04334.1 - 0.28 10.5 0.0 0.79 9.0 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain fn3 PF00041.21 EGB04335.1 - 3.4e-26 91.4 0.7 1.1e-06 28.8 0.1 4.9 4 0 0 4 4 4 4 Fibronectin type III domain DUF2460 PF09343.10 EGB04335.1 - 0.029 13.9 0.3 0.087 12.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 2217 (DUF2460) Pur_ac_phosph_N PF16656.5 EGB04335.1 - 0.1 13.2 11.1 1.4 9.6 0.2 4.4 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Big_4 PF07532.11 EGB04335.1 - 0.11 12.3 0.5 0.37 10.6 0.5 1.9 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) eIF2A PF08662.11 EGB04336.1 - 7e-45 153.3 0.0 5e-41 140.7 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EGB04336.1 - 7.3e-07 28.9 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 EGB04336.1 - 3.1e-05 24.2 0.1 0.8 10.0 0.0 5.2 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EGB04336.1 - 0.012 13.6 0.0 0.056 11.4 0.0 2.0 2 0 0 2 2 2 0 IKI3 family WD40 PF00400.32 EGB04336.1 - 0.076 13.9 3.5 97 4.1 0.0 5.6 6 1 1 7 7 7 0 WD domain, G-beta repeat ABC_tran PF00005.27 EGB04337.1 - 4e-47 160.2 0.0 2.5e-23 83.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB04337.1 - 1e-17 64.9 0.0 1e-05 25.5 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB04337.1 - 3.4e-05 23.5 0.1 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB04337.1 - 0.00011 22.7 1.6 0.38 11.1 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EGB04337.1 - 0.00031 21.3 0.4 1 9.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGB04337.1 - 0.00058 19.4 0.4 8.9 5.7 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGB04337.1 - 0.0047 16.8 0.1 2.7 7.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 EGB04337.1 - 0.018 15.2 0.9 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain MukB PF04310.12 EGB04337.1 - 0.024 14.4 0.4 2.4 7.9 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_28 PF13521.6 EGB04337.1 - 0.028 14.7 3.3 10 6.3 0.0 4.1 3 1 1 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 EGB04337.1 - 0.042 13.9 0.4 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 EGB04337.1 - 0.05 13.2 0.5 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EGB04337.1 - 0.079 12.7 0.1 7.4 6.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 EGB04337.1 - 0.097 12.0 0.6 0.8 9.0 0.0 2.3 3 0 0 3 3 3 0 AIG1 family RNA_helicase PF00910.22 EGB04337.1 - 0.14 12.6 0.1 30 5.1 0.1 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EGB04337.1 - 0.15 12.3 0.2 29 4.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF4162 PF13732.6 EGB04337.1 - 0.2 12.4 0.0 32 5.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_17 PF13207.6 EGB04337.1 - 0.25 11.8 2.4 29 5.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain L51_S25_CI-B8 PF05047.16 EGB04338.1 - 1.2e-06 28.3 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PhyH PF05721.13 EGB04340.1 - 2.2e-21 77.1 0.0 3.9e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RNA_GG_bind PF10258.9 EGB04342.1 - 0.018 15.1 0.1 11 6.2 0.1 3.1 3 0 0 3 3 3 0 PHAX RNA-binding domain DUF383 PF04063.14 EGB04343.1 - 2.4e-10 40.4 0.0 1.9e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGB04343.1 - 2e-07 30.7 0.0 4.9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) ASFV_J13L PF05568.11 EGB04343.1 - 2.7 7.7 5.5 0.49 10.1 1.5 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein Peptidase_S9 PF00326.21 EGB04344.1 - 1.6e-45 155.2 0.1 4e-44 150.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 EGB04344.1 - 3.3e-11 42.8 1.9 0.00094 19.1 0.1 4.6 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 EGB04344.1 - 1.8e-06 27.8 0.4 0.014 15.0 0.3 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EGB04344.1 - 0.0016 17.2 0.1 0.27 9.9 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EGB04344.1 - 0.015 14.9 2.3 7.6 6.1 0.0 2.5 1 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGB04344.1 - 0.042 13.7 0.1 0.44 10.4 0.1 2.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold CLP_protease PF00574.23 EGB04345.1 - 1.7e-77 259.5 0.3 1.9e-77 259.3 0.3 1.0 1 0 0 1 1 1 1 Clp protease PAS_9 PF13426.7 EGB04346.1 - 7.4e-15 55.1 0.0 9.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGB04346.1 - 1.7e-06 28.0 0.0 2.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EGB04346.1 - 3.2e-05 24.1 0.0 4.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGB04346.1 - 0.029 14.6 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 PAS fold Helicase_C PF00271.31 EGB04347.1 - 9.9e-11 42.0 0.0 1.9e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EGB04347.1 - 5.6e-07 29.8 0.2 9.9e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EGB04347.1 - 2.2e-05 24.3 0.0 7.6e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGB04347.1 - 0.0016 18.7 0.0 0.0046 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGB04347.1 - 0.018 14.1 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EGB04347.1 - 0.028 14.1 0.6 0.075 12.7 0.6 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB04347.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glycolytic PF00274.19 EGB04348.1 - 4.5e-118 394.0 0.0 5.4e-118 393.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Abhydrolase_1 PF00561.20 EGB04349.1 - 1.3e-08 34.8 0.0 4.1e-05 23.4 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB04349.1 - 2.8e-08 33.4 0.0 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EGB04349.1 - 1.4e-05 25.1 0.0 3.3e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Esterase PF00756.20 EGB04349.1 - 0.0004 20.1 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EGB04349.1 - 0.00084 19.2 0.0 0.02 14.7 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGB04349.1 - 0.0044 16.5 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EGB04349.1 - 0.03 13.9 0.0 0.068 12.7 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 EGB04349.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PseudoU_synth_2 PF00849.22 EGB04350.1 - 1e-22 80.9 0.0 2.4e-22 79.7 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase Anoctamin PF04547.12 EGB04351.1 - 6.2e-83 279.1 4.2 7.9e-83 278.8 4.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel TraB PF01963.17 EGB04351.1 - 3.7e-13 50.0 0.2 4e-06 26.9 0.3 2.2 2 0 0 2 2 2 2 TraB family Kelch_3 PF13415.6 EGB04351.1 - 9.6e-12 44.9 5.3 0.14 12.5 0.1 6.2 6 0 0 6 6 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGB04351.1 - 1.6e-11 44.1 6.7 7.1e-05 22.7 0.4 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB04351.1 - 6e-11 42.1 0.8 0.0034 17.4 0.1 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 EGB04351.1 - 7.4e-05 22.6 6.5 2.3 8.3 0.0 5.7 6 0 0 6 6 6 2 Kelch motif ANAPC4_WD40 PF12894.7 EGB04351.1 - 0.00022 21.4 0.0 0.0016 18.7 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 EGB04351.1 - 0.0056 16.5 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 HELP motif Anoct_dimer PF16178.5 EGB04351.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin WD40 PF00400.32 EGB04351.1 - 0.017 16.0 6.8 16 6.6 0.0 6.2 7 1 1 8 8 7 0 WD domain, G-beta repeat Kelch_6 PF13964.6 EGB04351.1 - 0.038 14.3 1.2 3.4 8.1 0.1 4.4 5 0 0 5 5 5 0 Kelch motif SUR7 PF06687.12 EGB04351.1 - 0.15 11.7 0.1 1.1 8.9 0.1 2.2 1 1 0 1 1 1 0 SUR7/PalI family SPW PF03779.14 EGB04351.1 - 4.9 6.8 9.6 4.7 6.9 0.4 4.0 3 0 0 3 3 3 0 SPW repeat Aminotran_5 PF00266.19 EGB04352.1 - 4.2e-13 49.0 0.0 1e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Sulfatase PF00884.23 EGB04354.1 - 2.6e-23 82.9 0.0 2.8e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Sulfatase PF00884.23 EGB04355.1 - 4.9e-30 105.0 0.0 6e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 EGB04355.1 - 0.0026 17.7 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 EGB04355.1 - 0.0037 17.5 0.0 0.0053 17.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 EGB04355.1 - 0.055 14.2 0.1 0.14 12.9 0.1 1.8 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase EF-hand_1 PF00036.32 EGB04356.1 - 4.1e-17 60.4 0.0 0.00033 20.0 0.0 6.2 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 EGB04356.1 - 8.4e-15 55.0 0.0 1.3e-05 25.5 0.2 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB04356.1 - 1.5e-13 49.5 1.1 0.031 13.8 0.0 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGB04356.1 - 8.6e-13 47.1 0.8 0.16 12.0 0.0 6.3 5 1 1 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 EGB04356.1 - 0.0012 18.7 2.2 2 8.3 0.0 4.9 5 0 0 5 5 5 1 EF-hand domain pair NIF PF03031.18 EGB04357.1 - 4.3e-46 156.5 0.1 5e-46 156.3 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EGB04357.1 - 0.0061 17.0 2.6 0.075 13.4 0.1 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.32 EGB04358.1 - 1.1e-15 55.9 5.8 6.7e-05 22.1 0.1 4.4 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGB04358.1 - 9.1e-15 54.9 5.8 1.5e-11 44.6 0.3 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB04358.1 - 1.9e-13 49.1 3.1 0.0047 16.7 0.2 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGB04358.1 - 8.9e-10 37.6 0.9 0.0048 16.3 0.1 3.6 3 1 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGB04358.1 - 2e-07 30.8 8.1 5.4e-05 22.9 0.4 3.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB04358.1 - 2.2e-05 24.7 0.9 3.1e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EGB04358.1 - 0.00055 19.9 3.7 0.22 11.5 0.3 3.2 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB04358.1 - 0.0086 16.4 0.3 0.03 14.6 0.0 1.9 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region PaO PF08417.12 EGB04359.1 - 7.5e-29 99.7 0.0 3.2e-28 97.7 0.0 2.0 2 0 0 2 2 2 1 Pheophorbide a oxygenase Rieske PF00355.26 EGB04359.1 - 2.2e-17 62.8 0.0 4.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain HAD_2 PF13419.6 EGB04360.1 - 1.3e-14 54.7 0.0 5.2e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB04360.1 - 5.4e-11 43.2 0.0 6.3e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB04360.1 - 8.6e-07 29.5 0.2 1.5e-06 28.8 0.2 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB04360.1 - 0.00049 20.1 0.1 0.0009 19.3 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Methyltransf_25 PF13649.6 EGB04361.1 - 4.9e-16 59.2 0.1 8.9e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB04361.1 - 6e-16 58.6 0.0 7.5e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB04361.1 - 1e-14 54.9 0.1 1.8e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB04361.1 - 2.6e-14 53.7 0.0 4.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB04361.1 - 8.1e-10 38.8 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB04361.1 - 9.2e-10 38.2 0.0 1.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGB04361.1 - 7.8e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EGB04361.1 - 0.00041 19.7 0.0 0.00062 19.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EGB04361.1 - 0.0012 18.9 0.1 0.0045 17.1 0.1 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EGB04361.1 - 0.0022 17.8 0.1 0.0047 16.7 0.1 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EGB04361.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGB04361.1 - 0.03 14.3 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EGB04361.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase ABC_tran PF00005.27 EGB04362.1 - 5.8e-16 59.3 0.0 9.8e-16 58.5 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB04362.1 - 2.5e-06 27.6 0.1 1.1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB04362.1 - 4.5e-05 23.9 0.6 7e-05 23.3 0.6 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGB04362.1 - 0.00013 21.6 5.8 0.088 12.4 2.5 2.3 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 EGB04362.1 - 0.00065 19.9 0.2 0.0036 17.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EGB04362.1 - 0.0035 17.6 0.1 0.012 15.8 0.1 1.9 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 EGB04362.1 - 0.0071 16.3 0.0 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_29 PF13555.6 EGB04362.1 - 0.0087 15.8 0.2 0.044 13.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 EGB04362.1 - 0.0092 15.9 0.3 0.02 14.8 0.1 1.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EGB04362.1 - 0.0098 16.2 0.1 0.047 14.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGB04362.1 - 0.01 15.8 0.3 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SMC_N PF02463.19 EGB04362.1 - 0.012 15.1 0.0 0.14 11.5 0.0 1.9 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain CbiA PF01656.23 EGB04362.1 - 0.014 15.5 0.4 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EGB04362.1 - 0.026 15.1 0.0 0.039 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB04362.1 - 0.032 14.6 0.1 0.05 14.0 0.1 1.3 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EGB04362.1 - 0.038 13.9 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 EGB04362.1 - 0.046 12.9 0.2 0.12 11.5 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 EGB04362.1 - 0.062 13.7 0.1 0.15 12.5 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) P22_AR_N PF10547.9 EGB04362.1 - 0.13 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 P22_AR N-terminal domain IstB_IS21 PF01695.17 EGB04362.1 - 0.14 11.9 0.1 1 9.1 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGB04362.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB04362.1 - 0.44 10.2 6.2 1.4 8.6 6.2 1.8 1 1 0 1 1 1 0 AAA domain Adaptin_N PF01602.20 EGB04363.1 - 7.3e-110 368.0 0.4 9.1e-110 367.7 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGB04363.1 - 1.1e-16 61.2 2.2 5.7e-11 42.7 0.1 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGB04363.1 - 1.2e-05 25.5 0.1 3.7 7.8 0.1 4.5 2 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 EGB04363.1 - 1.4e-05 25.4 2.9 0.63 10.5 0.0 5.5 4 1 1 5 5 5 2 HEAT repeats DNA_pol_phi PF04931.13 EGB04363.1 - 0.15 10.2 5.4 0.15 10.2 1.2 2.1 2 0 0 2 2 2 0 DNA polymerase phi DUF3246 PF11596.8 EGB04363.1 - 0.22 10.9 0.8 0.37 10.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF5400 PF17379.2 EGB04363.1 - 0.25 11.8 0.6 0.66 10.5 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5400) Radical_SAM PF04055.21 EGB04364.1 - 3.5e-28 99.1 0.0 7.3e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EGB04364.1 - 1.2e-26 92.6 0.1 5.3e-26 90.5 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EGB04364.1 - 1.8e-14 53.4 0.7 3.8e-14 52.4 0.7 1.6 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 EGB04364.1 - 0.00012 22.1 2.0 0.0053 16.9 0.3 2.9 2 1 0 2 2 2 1 TRAM domain Lipase_GDSL_2 PF13472.6 EGB04364.1 - 0.002 18.6 0.7 0.24 11.8 0.7 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fer4_12 PF13353.6 EGB04364.1 - 0.051 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Peptidase_M19 PF01244.21 EGB04364.1 - 0.094 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) cNMP_binding PF00027.29 EGB04365.1 - 3.3e-14 52.7 0.0 7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB04365.1 - 3.7e-09 36.2 0.0 5.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ion transport protein Pkinase PF00069.25 EGB04366.1 - 3.2e-36 125.1 0.0 3.5e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04366.1 - 6.8e-22 78.0 0.0 7.4e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB04366.1 - 0.0042 17.1 0.0 0.0052 16.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB04366.1 - 0.005 15.8 0.0 0.0058 15.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGB04366.1 - 0.047 13.0 0.0 0.066 12.6 0.0 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPA_interact_N PF14766.6 EGB04368.1 - 0.0037 16.9 1.6 0.0088 15.7 1.6 1.6 1 0 0 1 1 1 1 Replication protein A interacting N-terminal ATP-synt_F PF01990.17 EGB04370.1 - 0.00037 20.7 0.0 0.00075 19.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit SBF2 PF12335.8 EGB04370.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Myotubularin protein SET PF00856.28 EGB04371.1 - 5.1e-12 46.5 0.0 9e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EGB04371.1 - 0.096 13.4 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding TFIIIC_sub6 PF10419.9 EGB04372.1 - 0.0031 17.3 0.0 0.01 15.7 0.0 2.0 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Ig_mannosidase PF17753.1 EGB04373.1 - 5.2e-13 48.6 0.1 1.2e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 EGB04373.1 - 1.5e-05 25.6 0.0 2.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EGB04373.1 - 0.089 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EGB04373.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Glyco_transf_8 PF01501.20 EGB04374.1 - 0.0011 18.5 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGB04374.1 - 0.059 12.7 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative PAH PF02671.21 EGB04375.1 - 2.7e-07 30.6 0.0 6.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat zf-C2HC_2 PF13913.6 EGB04375.1 - 0.012 15.5 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 EGB04375.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 EGB04375.1 - 0.19 12.2 0.2 0.35 11.4 0.2 1.3 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain RsbRD_N PF14361.6 EGB04375.1 - 0.23 12.2 2.1 0.42 11.3 0.0 2.4 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Aminotran_1_2 PF00155.21 EGB04377.1 - 1.5e-44 152.7 0.0 1.8e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 EGB04378.1 - 4.4e-38 128.6 3.7 2.2e-09 37.8 0.7 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04378.1 - 2.7e-06 27.6 0.0 0.00021 21.5 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BolA PF01722.18 EGB04379.1 - 1.4e-16 60.5 0.0 3.8e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Mlh1_C PF16413.5 EGB04380.1 - 1.2e-56 192.0 0.0 2.4e-56 191.1 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EGB04380.1 - 1.1e-17 63.8 0.0 1.9e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGB04380.1 - 6.1e-10 39.1 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGB04380.1 - 0.00057 20.4 0.0 0.0014 19.1 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.14 EGB04380.1 - 0.28 9.4 3.5 0.43 8.8 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 EGB04380.1 - 0.54 8.7 12.5 0.83 8.1 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Dicty_REP PF05086.12 EGB04380.1 - 3.9 5.3 9.4 5.3 4.9 9.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGB04380.1 - 4.3 7.3 12.3 11 6.1 12.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein LapA_dom PF06305.11 EGB04381.1 - 0.11 12.3 3.2 7 6.6 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Vma12 PF11712.8 EGB04381.1 - 0.62 10.1 3.8 12 6.0 0.4 2.4 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase AAA_25 PF13481.6 EGB04382.1 - 0.042 13.4 0.0 0.052 13.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain Rdx PF10262.9 EGB04382.1 - 0.095 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Rdx family acVLRF1 PF18859.1 EGB04382.1 - 0.11 12.8 0.4 0.16 12.2 0.4 1.2 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor YCII PF03795.14 EGB04383.1 - 3.1e-06 27.5 0.0 6.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 YCII-related domain FAD_binding_3 PF01494.19 EGB04384.1 - 7.1e-14 51.8 5.4 2.8e-07 30.1 0.4 2.5 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EGB04384.1 - 0.011 16.0 4.1 0.036 14.3 2.8 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGB04384.1 - 1 8.4 10.3 1.9 7.5 10.3 1.7 1 1 0 1 1 1 0 FAD binding domain adh_short PF00106.25 EGB04385.1 - 0.0021 17.6 0.0 0.0021 17.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase WD40 PF00400.32 EGB04386.1 - 2.3e-23 82.0 3.3 2.4e-07 31.3 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40_like PF17005.5 EGB04386.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.4 1 1 1 2 2 2 0 WD40-like domain Nup160 PF11715.8 EGB04386.1 - 0.018 13.7 0.9 0.067 11.8 0.5 2.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGB04386.1 - 0.043 14.1 0.2 1.9 8.8 0.1 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PHTB1_N PF14727.6 EGB04386.1 - 0.18 11.1 0.1 0.22 10.8 0.1 1.1 1 0 0 1 1 1 0 PTHB1 N-terminus Aminotran_5 PF00266.19 EGB04387.1 - 6.3e-42 143.9 0.0 7.8e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V His_Phos_2 PF00328.22 EGB04388.1 - 9.5e-10 38.4 0.0 0.002 17.5 0.2 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Exostosin PF03016.15 EGB04389.1 - 1.6e-20 73.6 0.0 6.6e-07 28.8 0.0 3.4 3 0 0 3 3 3 3 Exostosin family DUF1648 PF07853.11 EGB04389.1 - 2.6e-05 23.8 0.0 3.4 7.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF1648) CC PF04942.14 EGB04389.1 - 0.032 14.4 5.2 29 5.0 0.1 3.9 3 0 0 3 3 3 0 CC domain Tugs PF17840.1 EGB04389.1 - 4.4 7.6 5.9 51 4.1 0.1 3.4 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain PsbU PF06514.11 EGB04390.1 - 6e-27 93.5 0.1 7.3e-27 93.2 0.1 1.1 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 EGB04390.1 - 0.00048 20.3 0.0 0.00094 19.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif UCR_Fe-S_N PF10399.9 EGB04390.1 - 0.22 10.9 4.0 0.24 10.8 3.2 1.6 1 1 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ASL_C PF08328.11 EGB04391.1 - 2e-43 147.1 0.0 3.5e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Lyase_1 PF00206.20 EGB04391.1 - 2.1e-38 132.5 0.0 2.8e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Lyase AAA_5 PF07728.14 EGB04393.1 - 1.4e-78 261.6 0.0 1.2e-29 103.1 0.0 3.2 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB04393.1 - 3.8e-07 30.6 12.0 0.053 13.9 0.0 5.7 5 1 1 6 6 6 2 AAA ATPase domain AAA_18 PF13238.6 EGB04393.1 - 0.00035 21.1 0.0 0.17 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGB04393.1 - 0.00072 19.8 0.6 6.2 7.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EGB04393.1 - 0.00096 19.3 0.0 0.0092 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGB04393.1 - 0.0048 17.3 0.0 2.1 8.7 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGB04393.1 - 0.0062 16.3 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGB04393.1 - 0.0076 16.1 0.0 4.2 7.2 0.0 3.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGB04393.1 - 0.0081 15.6 0.1 7.1 5.9 0.0 3.9 3 1 1 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGB04393.1 - 0.023 14.9 0.1 19 5.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EGB04393.1 - 0.023 14.9 0.1 0.13 12.5 0.1 2.4 3 1 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EGB04393.1 - 0.11 11.9 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EGB04393.1 - 0.12 11.5 0.0 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGB04393.1 - 0.14 11.8 0.0 7.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain PAS_9 PF13426.7 EGB04394.1 - 1.7e-16 60.4 0.0 1.7e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGB04394.1 - 0.00053 20.0 0.0 0.0006 19.8 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EGB04394.1 - 0.0015 18.8 0.0 0.0018 18.5 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGB04394.1 - 0.017 15.4 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 PAS fold TUDOR_5 PF18359.1 EGB04395.1 - 2.6e-05 23.8 0.1 4.4e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 SARAF PF06682.12 EGB04395.1 - 0.33 10.5 1.0 0.35 10.5 0.0 1.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SKG6 PF08693.10 EGB04395.1 - 2.5 7.6 4.7 4.6 6.7 4.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Trypsin PF00089.26 EGB04396.1 - 1e-43 149.7 12.2 8.5e-43 146.7 0.0 3.1 2 1 1 3 3 3 2 Trypsin Trypsin_2 PF13365.6 EGB04396.1 - 0.0065 17.4 0.2 0.018 16.0 0.0 1.9 2 1 0 2 2 2 1 Trypsin-like peptidase domain Dynein_light PF01221.18 EGB04396.1 - 0.34 11.3 3.1 7.3 7.0 0.0 3.1 3 0 0 3 3 3 0 Dynein light chain type 1 RPA_C PF08784.11 EGB04397.1 - 3.5e-16 59.7 0.8 9.2e-16 58.4 0.3 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EGB04397.1 - 3e-08 33.5 0.2 5.8e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EGB04397.1 - 4.7e-05 23.5 1.2 0.0012 19.0 0.2 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 EGB04397.1 - 0.0005 19.1 0.1 0.00075 18.5 0.1 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 RMI2 PF16100.5 EGB04397.1 - 0.0042 16.9 0.1 0.0067 16.3 0.1 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 CDC24_OB3 PF17244.2 EGB04397.1 - 0.1 12.3 0.4 0.23 11.1 0.1 1.6 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 CwfJ_C_1 PF04677.15 EGB04398.1 - 2e-21 76.1 0.0 3.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 EGB04398.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HIT PF01230.23 EGB04398.1 - 0.0024 18.6 0.1 0.0045 17.7 0.1 1.3 1 0 0 1 1 1 1 HIT domain CwfJ_C_2 PF04676.14 EGB04398.1 - 0.0078 17.1 0.0 0.014 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CAF1C_H4-bd PF12265.8 EGB04399.1 - 2.9e-19 69.1 0.0 1.1e-18 67.3 0.0 1.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGB04399.1 - 1.1e-11 45.0 2.9 0.036 14.9 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat CDC45 PF02724.14 EGB04400.1 - 1.3e-130 436.7 0.0 2.1e-88 297.3 0.0 2.5 1 1 1 2 2 2 2 CDC45-like protein YL1 PF05764.13 EGB04400.1 - 0.029 14.5 9.3 0.046 13.8 9.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 EGB04400.1 - 0.48 9.8 8.9 0.7 9.3 8.9 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.11 EGB04400.1 - 0.71 9.2 5.4 1.1 8.6 5.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Spt5_N PF11942.8 EGB04400.1 - 1.1 10.2 14.5 2.4 9.2 14.5 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal FRQ PF09421.10 EGB04400.1 - 1.3 6.9 6.7 1.9 6.4 6.7 1.1 1 0 0 1 1 1 0 Frequency clock protein Nop14 PF04147.12 EGB04400.1 - 2.9 6.0 9.5 4.1 5.5 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family Gln-synt_C PF00120.24 EGB04401.1 - 1.2e-95 320.5 0.0 1.4e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGB04401.1 - 0.00037 20.2 0.0 0.00075 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 EGB04401.1 - 0.13 12.1 1.1 0.91 9.4 0.1 2.7 2 1 0 2 2 2 0 Glutamine synthetase N-terminal domain Presenilin PF01080.17 EGB04402.1 - 9.3e-72 242.0 13.3 9.7e-48 162.9 0.9 2.1 1 1 1 2 2 2 2 Presenilin DUF3611 PF12263.8 EGB04402.1 - 3.4e-09 36.9 1.4 3.4e-09 36.9 1.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3611) Ion_trans_2 PF07885.16 EGB04403.1 - 7.7e-09 35.4 4.3 1e-08 35.0 4.3 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB04403.1 - 0.00047 19.5 2.2 0.00055 19.2 2.2 1.1 1 0 0 1 1 1 1 Ion transport protein UPF0114 PF03350.16 EGB04403.1 - 0.031 14.5 0.2 0.034 14.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Cupin_4 PF08007.12 EGB04404.1 - 9.5e-35 120.6 0.0 1.7e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EGB04404.1 - 2.8e-06 27.3 0.0 6.5e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain YL1 PF05764.13 EGB04404.1 - 0.028 14.5 1.4 0.043 13.9 1.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 EGB04404.1 - 0.077 12.9 2.0 0.12 12.2 2.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cupin_1 PF00190.22 EGB04404.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin SDA1 PF05285.12 EGB04404.1 - 0.32 10.4 2.8 0.48 9.8 2.8 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EGB04404.1 - 0.43 8.8 2.5 0.61 8.3 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EGB04404.1 - 0.61 8.6 2.1 0.84 8.1 2.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EGB04404.1 - 0.66 8.1 2.4 0.9 7.7 2.4 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGB04404.1 - 1.5 6.8 14.2 2.4 6.1 14.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 EGB04404.1 - 3 7.5 14.9 0.059 13.1 6.5 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 EGB04404.1 - 5.8 5.9 16.4 10 5.1 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 EGB04405.1 - 4.6e-39 134.4 0.0 5.1e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04405.1 - 8.3e-18 64.6 0.0 1e-17 64.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04405.1 - 3.8e-07 29.7 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB04405.1 - 0.0015 17.4 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB04405.1 - 0.008 16.1 0.1 0.016 15.2 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB04405.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YjcZ_2 PF09680.10 EGB04405.1 - 0.1 12.2 2.9 0.19 11.4 2.9 1.4 1 0 0 1 1 1 0 Family of unknown function SIR2 PF02146.17 EGB04407.1 - 3.9e-46 157.2 0.0 5e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family S-AdoMet_synt_M PF02772.16 EGB04408.1 - 1.4e-38 131.8 0.0 2.8e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGB04408.1 - 6.5e-38 129.4 0.3 1.4e-37 128.4 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.16 EGB04408.1 - 7e-27 94.1 2.6 1.6e-26 92.9 2.6 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain Chloroa_b-bind PF00504.21 EGB04409.1 - 3.4e-31 109.0 1.1 7.2e-22 78.6 0.1 2.7 2 1 1 3 3 3 2 Chlorophyll A-B binding protein Sulfatase PF00884.23 EGB04410.1 - 3.1e-52 177.9 0.0 3.9e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB04410.1 - 0.0099 15.5 1.6 0.025 14.2 1.6 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Aldedh PF00171.22 EGB04411.1 - 4.7e-85 285.8 0.0 5.3e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGB04411.1 - 0.22 11.0 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) p25-alpha PF05517.12 EGB04412.1 - 1.1e-24 87.4 0.1 1.2e-24 87.2 0.1 1.0 1 0 0 1 1 1 1 p25-alpha Ferric_reduct PF01794.19 EGB04413.1 - 2e-15 57.0 10.0 5.1e-15 55.7 10.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGB04413.1 - 6e-10 39.5 0.0 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGB04413.1 - 2.8e-06 27.4 0.0 8.8e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain MORN PF02493.20 EGB04414.1 - 6.7e-11 41.4 22.8 4.4e-05 23.1 0.4 5.7 7 0 0 7 7 7 5 MORN repeat Methyltransf_16 PF10294.9 EGB04415.1 - 6.1e-27 94.5 0.0 8.2e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGB04415.1 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PKD_channel PF08016.12 EGB04416.1 - 3.8e-47 160.9 4.4 7.1e-47 160.0 4.4 1.3 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EGB04416.1 - 3.8e-07 29.6 15.7 6.3e-07 28.9 15.7 1.2 1 0 0 1 1 1 1 Ion transport protein ABC_tran PF00005.27 EGB04417.1 - 2.4e-14 54.0 0.0 4.2e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB04417.1 - 1e-05 25.5 0.5 0.028 14.2 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGB04417.1 - 0.0022 17.6 2.7 0.0034 17.0 2.7 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGB04417.1 - 0.0069 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 EGB04417.1 - 0.016 15.5 0.3 0.016 15.5 0.3 1.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGB04417.1 - 0.025 14.3 0.2 0.071 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGB04417.1 - 0.044 14.0 0.8 0.27 11.5 0.7 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EGB04417.1 - 0.099 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase CBM_10 PF02013.16 EGB04417.1 - 0.1 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Cellulose or protein binding domain MMR_HSR1 PF01926.23 EGB04417.1 - 0.12 12.4 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EGB04417.1 - 0.18 12.3 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB04417.1 - 0.31 10.9 1.7 1.3 9.0 0.1 2.1 2 1 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EGB04417.1 - 2 8.1 6.1 4.4 7.0 6.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB04418.1 - 2e-09 38.1 0.0 5.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB04418.1 - 7.6e-07 29.2 0.0 0.0095 15.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB04418.1 - 0.0019 17.7 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB04418.1 - 0.0086 15.8 0.1 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGB04418.1 - 0.017 14.7 0.5 0.074 12.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGB04418.1 - 0.027 14.2 0.7 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGB04418.1 - 0.067 13.4 0.5 0.25 11.6 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB04418.1 - 0.11 12.8 2.8 0.46 10.9 2.8 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EGB04418.1 - 0.3 11.6 0.0 0.44 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 EGB04418.1 - 0.42 9.4 0.9 1.5 7.6 0.1 1.9 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) RINGv PF12906.7 EGB04421.1 - 2.9e-12 46.5 2.7 2.9e-12 46.5 2.7 1.7 2 0 0 2 2 2 1 RING-variant domain TPR_10 PF13374.6 EGB04421.1 - 0.0003 20.6 0.1 0.00084 19.1 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB04421.1 - 0.00055 20.2 0.0 0.0019 18.5 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 EGB04421.1 - 0.0021 18.4 2.8 0.0021 18.4 2.8 1.7 2 0 0 2 2 2 1 Ring finger domain acVLRF1 PF18859.1 EGB04421.1 - 0.013 15.8 0.7 0.031 14.6 0.7 1.7 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor zf-RING_5 PF14634.6 EGB04421.1 - 0.14 12.1 2.9 0.78 9.7 2.9 2.2 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 EGB04421.1 - 0.19 12.0 1.6 0.38 10.9 1.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EGB04421.1 - 7 6.5 12.7 0.17 11.7 5.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain EF-hand_1 PF00036.32 EGB04422.1 - 1.4e-27 93.1 6.6 3e-06 26.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB04422.1 - 4e-25 87.4 4.7 1.8e-10 40.5 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 EGB04422.1 - 6.4e-25 87.4 0.6 1e-11 45.1 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB04422.1 - 4.2e-24 82.4 6.6 2e-05 24.1 0.2 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB04422.1 - 6.4e-22 76.0 12.0 3.8e-05 23.0 0.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 EGB04422.1 - 0.00015 21.7 0.0 0.3 11.1 0.0 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB04422.1 - 0.0012 19.2 0.0 0.07 13.5 0.0 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGB04422.1 - 0.0036 17.1 0.3 12 5.8 0.2 3.4 2 2 1 3 3 3 1 EF hand EF-hand_9 PF14658.6 EGB04422.1 - 0.023 15.0 0.0 0.36 11.2 0.0 2.1 2 1 0 2 2 2 0 EF-hand domain TerB PF05099.13 EGB04422.1 - 0.029 14.3 0.1 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TerB Excalibur PF05901.11 EGB04422.1 - 0.12 13.0 2.8 6.1 7.6 0.1 3.0 3 0 0 3 3 3 0 Excalibur calcium-binding domain CDC45 PF02724.14 EGB04423.1 - 0.0038 15.6 4.2 0.0059 15.0 4.2 1.2 1 0 0 1 1 1 1 CDC45-like protein WD40 PF00400.32 EGB04423.1 - 0.03 15.2 5.4 4.1 8.4 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Myc_N PF01056.18 EGB04423.1 - 0.066 13.1 1.2 0.11 12.4 1.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 EGB04423.1 - 0.19 11.4 7.2 0.88 9.2 5.9 2.3 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.14 EGB04423.1 - 1.4 8.6 11.0 2.2 8.0 7.4 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PQQ_3 PF13570.6 EGB04423.1 - 5.4 7.7 22.5 2.7 8.6 0.1 5.8 6 0 0 6 6 6 0 PQQ-like domain PP2C PF00481.21 EGB04424.1 - 5.4e-42 144.2 0.0 1.2e-41 143.1 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C 2OG-FeII_Oxy_5 PF13759.6 EGB04424.1 - 3.4e-11 43.5 0.0 9.1e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Ank_2 PF12796.7 EGB04424.1 - 1.4e-07 32.0 0.1 0.0002 21.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) AAA_19 PF13245.6 EGB04424.1 - 3.2e-05 24.3 0.0 0.00076 19.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Ank_5 PF13857.6 EGB04424.1 - 6.5e-05 23.1 0.2 0.67 10.4 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB04424.1 - 8.5e-05 22.8 1.0 0.31 11.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB04424.1 - 0.00019 21.6 0.0 1.5 9.6 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGB04424.1 - 0.0016 19.0 0.1 0.055 14.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) UvrD_C_2 PF13538.6 EGB04424.1 - 0.095 12.5 7.1 0.97 9.3 0.2 3.5 4 0 0 4 4 4 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EGB04424.1 - 0.12 11.9 10.7 0.13 11.7 0.0 3.2 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain SAP PF02037.27 EGB04424.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 SAP domain ResIII PF04851.15 EGB04424.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ketoacyl-synt PF00109.26 EGB04425.1 - 3e-23 82.7 13.3 3e-23 82.7 13.3 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB04425.1 - 1.9e-08 34.3 0.6 3.8e-08 33.4 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain FMO-like PF00743.19 EGB04426.1 - 2.7e-39 135.0 0.0 1.8e-30 105.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGB04426.1 - 4.4e-13 49.2 0.0 3.6e-12 46.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB04426.1 - 8.1e-09 35.1 0.0 1.7e-06 27.4 0.0 2.4 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGB04426.1 - 2.5e-07 30.2 0.0 1e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGB04426.1 - 0.0033 17.8 0.1 2.5 8.6 0.0 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EGB04426.1 - 0.0049 17.1 0.2 0.023 14.9 0.0 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGB04426.1 - 0.012 15.7 0.5 0.32 11.0 0.5 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EGB04426.1 - 0.034 14.2 0.0 8.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGB04426.1 - 0.036 14.6 0.0 3.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGB04426.1 - 0.039 13.3 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Kdo PF06293.14 EGB04427.1 - 2.2e-09 37.0 0.0 3.9e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGB04427.1 - 6.6e-08 32.2 0.0 8.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGB04427.1 - 1.4e-06 28.5 4.4 0.0036 17.2 1.7 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EGB04427.1 - 3.1e-05 23.7 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 EGB04427.1 - 0.00058 19.3 0.0 0.00071 19.0 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGB04427.1 - 0.0015 17.5 0.0 0.0019 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF4381 PF14316.6 EGB04427.1 - 0.026 14.7 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pkinase_Tyr PF07714.17 EGB04427.1 - 0.16 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase GFO_IDH_MocA PF01408.22 EGB04428.1 - 1.2e-17 64.8 0.1 3.9e-17 63.2 0.1 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PsbQ PF05757.11 EGB04428.1 - 0.00011 22.0 5.6 0.00011 22.0 5.6 2.5 2 0 0 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) DUF4327 PF14217.6 EGB04428.1 - 0.016 15.4 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) 2OG-FeII_Oxy_3 PF13640.6 EGB04429.1 - 2.7e-12 47.4 0.0 4.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB04429.1 - 0.053 14.0 0.0 0.079 13.5 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ATP-synt_D PF01813.17 EGB04430.1 - 5e-64 215.7 0.4 6e-64 215.5 0.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Leptin PF02024.15 EGB04430.1 - 0.067 13.0 0.4 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Leptin Sec7 PF01369.20 EGB04431.1 - 1.7e-33 115.9 0.0 2.1e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EGB04431.1 - 3.4e-05 24.3 0.0 5.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 PH domain FhuF_C PF11575.8 EGB04431.1 - 0.12 12.4 0.3 7.7 6.6 0.2 2.3 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DEAD PF00270.29 EGB04432.1 - 6.8e-23 81.3 0.0 1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB04432.1 - 8e-21 74.5 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CAF1C_H4-bd PF12265.8 EGB04432.1 - 2.3e-09 37.3 0.0 4.2e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGB04432.1 - 2.5e-07 31.2 8.7 0.01 16.7 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ResIII PF04851.15 EGB04432.1 - 0.0058 16.7 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGB04432.1 - 0.18 12.2 0.1 0.44 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 EGB04432.1 - 0.34 9.6 0.1 0.52 9.0 0.1 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF2890 PF11081.8 EGB04432.1 - 7.1 6.7 8.8 0.57 10.3 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Methyltransf_25 PF13649.6 EGB04433.1 - 2.7e-09 37.6 0.1 4.9e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGB04433.1 - 1.2e-08 34.8 0.1 1.8e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGB04433.1 - 1.7e-07 31.7 0.1 3e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGB04433.1 - 6.2e-05 23.0 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB04433.1 - 0.00014 22.6 0.0 0.00022 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB04433.1 - 0.0002 20.9 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EGB04433.1 - 0.00052 19.4 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGB04433.1 - 0.0024 17.7 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB04433.1 - 0.0063 16.3 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGB04433.1 - 0.013 16.5 0.1 0.024 15.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 EGB04433.1 - 0.025 13.5 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 EGB04433.1 - 0.056 13.1 0.1 0.083 12.5 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 EGB04433.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Acyl_transf_1 PF00698.21 EGB04434.1 - 7.7e-05 22.3 3.3 0.00027 20.5 3.3 1.7 1 1 0 1 1 1 1 Acyl transferase domain Peptidase_C1 PF00112.23 EGB04435.1 - 1.6e-48 165.7 6.6 2.2e-48 165.2 6.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB04435.1 - 3.1e-05 22.9 1.2 0.069 11.9 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family adh_short PF00106.25 EGB04436.1 - 4.2e-38 130.8 0.4 5.7e-38 130.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB04436.1 - 6.1e-21 75.0 1.1 8.1e-21 74.7 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EGB04436.1 - 0.0016 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EGB04436.1 - 0.006 16.5 0.3 0.27 11.1 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EGB04436.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RRM_1 PF00076.22 EGB04437.1 - 1.1e-11 44.3 0.0 2.1e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGB04437.1 - 0.00018 21.1 0.0 0.00021 20.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAS-barrel PF09378.10 EGB04437.1 - 0.055 13.6 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 HAS barrel domain MtrB_PioB PF11854.8 EGB04438.1 - 2.2 6.5 8.0 3.3 6.0 8.0 1.1 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB DUF3597 PF12200.8 EGB04439.1 - 0.18 12.3 0.8 0.38 11.3 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Enolase_C PF00113.22 EGB04440.1 - 1e-127 425.5 0.0 1.6e-127 424.8 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGB04440.1 - 5.7e-44 149.5 0.2 3.1e-43 147.1 0.2 2.1 1 1 0 1 1 1 1 Enolase, N-terminal domain Exostosin PF03016.15 EGB04440.1 - 6.6e-15 55.1 0.0 7.9e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Exostosin family MAAL_C PF07476.11 EGB04440.1 - 0.00016 20.9 0.3 0.00016 20.9 0.3 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus DUF5428 PF17493.2 EGB04440.1 - 0.17 12.4 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5428) Mpv17_PMP22 PF04117.12 EGB04441.1 - 5.9e-19 68.1 0.1 1.3e-18 67.0 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family AA_permease_2 PF13520.6 EGB04442.1 - 6e-34 117.6 11.5 8.4e-34 117.1 11.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGB04442.1 - 3.1e-05 22.8 11.5 0.00048 18.9 1.4 2.4 2 1 0 2 2 2 2 Amino acid permease Aa_trans PF01490.18 EGB04442.1 - 0.054 12.2 0.1 0.083 11.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein RRM_1 PF00076.22 EGB04443.1 - 1.3e-42 143.5 0.0 1.3e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGB04443.1 - 1e-05 25.4 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGB04443.1 - 0.00076 19.5 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 EGB04443.1 - 0.014 15.4 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 EGB04443.1 - 0.016 15.3 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif DUF2733 PF10813.8 EGB04443.1 - 0.16 11.8 4.3 7.1 6.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2733) RRM_occluded PF16842.5 EGB04443.1 - 0.18 11.7 0.0 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4944 PF16302.5 EGB04443.1 - 0.25 11.4 0.7 20 5.3 0.1 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4944) HSF_DNA-bind PF00447.17 EGB04444.1 - 6.5e-05 23.5 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding SlyX PF04102.12 EGB04444.1 - 0.055 14.1 0.8 0.15 12.7 0.8 1.8 1 0 0 1 1 1 0 SlyX NUDIX PF00293.28 EGB04445.1 - 5.1e-20 71.9 0.1 6e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EGB04445.1 - 0.0032 17.4 0.1 0.0041 17.1 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.7 EGB04446.1 - 2.1e-23 84.1 12.2 2.4e-23 83.9 12.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB04446.1 - 4e-17 62.7 0.2 1.4e-15 57.7 0.4 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB04446.1 - 4.4e-17 62.2 0.2 4e-16 59.0 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGB04446.1 - 0.0043 16.7 0.3 0.0069 16.1 0.3 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EGB04446.1 - 0.0078 16.0 0.0 9.5 6.0 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGB04446.1 - 0.034 13.6 0.1 2.2 7.7 0.5 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family ProRS-C_1 PF09180.11 EGB04448.1 - 4.7e-23 81.2 0.1 9.6e-23 80.2 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EGB04448.1 - 1.5e-17 63.5 0.0 3.2e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGB04448.1 - 1.1e-14 54.8 0.0 1.7e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AMP-binding_C PF13193.6 EGB04449.1 - 9.2e-20 71.4 0.1 1.3e-19 70.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EGB04449.1 - 2.3e-16 59.4 0.3 3.2e-16 59.0 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme N6-adenineMlase PF10237.9 EGB04451.1 - 5e-30 104.4 0.0 7.7e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase TMEM151 PF14857.6 EGB04451.1 - 5.8e-10 38.7 0.0 8.7e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 TMEM151 family Lipase_GDSL_2 PF13472.6 EGB04452.1 - 1.7e-11 44.8 1.2 1.7e-11 44.8 1.2 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB04452.1 - 0.044 13.8 0.1 0.55 10.2 0.1 2.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase KxDL PF10241.9 EGB04453.1 - 0.011 16.0 1.9 0.011 16.0 1.9 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein YbfN PF13982.6 EGB04453.1 - 0.015 15.6 0.4 0.071 13.4 0.0 2.0 1 1 2 3 3 3 0 YbfN-like lipoprotein SpoIIID PF12116.8 EGB04453.1 - 0.031 14.4 1.1 0.043 13.9 0.8 1.6 1 1 0 1 1 1 0 Stage III sporulation protein D APG6_N PF17675.1 EGB04453.1 - 0.058 13.9 9.0 0.062 13.8 8.2 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 EGB04453.1 - 0.47 9.3 11.7 0.7 8.7 11.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 EGB04453.1 - 0.5 10.2 6.5 0.59 9.9 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HAUS6_N PF14661.6 EGB04453.1 - 4.2 6.9 9.9 1.8 8.1 2.4 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus MRPL52 PF18699.1 EGB04453.1 - 7.4 6.8 8.3 1.5 9.1 2.7 2.1 1 1 1 2 2 2 0 Mitoribosomal protein mL52 EF-hand_8 PF13833.6 EGB04454.1 - 1e-11 44.5 2.6 4.9e-06 26.3 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB04454.1 - 3.4e-11 41.9 1.6 1.9e-06 27.0 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB04454.1 - 1.1e-10 41.8 1.6 3.5e-05 24.2 0.3 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB04454.1 - 3.6e-06 26.5 3.8 0.00023 20.9 0.5 2.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB04454.1 - 0.00023 20.5 3.9 0.00023 20.5 0.1 2.6 2 1 1 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 EGB04454.1 - 0.0041 17.4 0.4 0.0056 17.0 0.4 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.32 EGB04455.1 - 1.7e-23 80.4 0.6 2.8e-05 23.3 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB04455.1 - 7.2e-22 77.6 1.7 3.5e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB04455.1 - 1.4e-17 62.0 0.6 1.6e-05 24.5 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB04455.1 - 1.9e-17 61.9 0.3 0.00018 20.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB04455.1 - 1.3e-16 60.1 3.7 1e-06 28.5 0.0 3.9 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB04455.1 - 3.9e-06 27.2 0.1 0.0087 16.4 0.0 2.7 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGB04455.1 - 5e-06 26.4 1.0 0.35 10.9 0.1 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGB04455.1 - 0.0091 15.8 0.4 5.5 6.9 0.0 3.6 3 1 1 4 4 4 1 EF hand TerB PF05099.13 EGB04455.1 - 0.019 14.9 0.4 2.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB NifU_N PF01592.16 EGB04456.1 - 7.1e-52 174.9 0.2 8.2e-52 174.7 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF3659 PF12396.8 EGB04456.1 - 0.036 14.0 1.3 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) HTH_24 PF13412.6 EGB04456.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Alg6_Alg8 PF03155.15 EGB04457.1 - 4.6e-109 365.6 0.0 8.9e-109 364.6 0.0 1.4 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family GT87 PF09594.10 EGB04457.1 - 0.00083 19.1 18.9 0.00083 19.1 18.9 3.6 1 1 1 2 2 2 1 Glycosyltransferase family 87 His_Phos_1 PF00300.22 EGB04458.1 - 4e-19 69.1 0.0 3.3e-18 66.1 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ephrin_rec_like PF07699.13 EGB04459.1 - 2.9e-20 71.7 24.6 2.7e-08 33.4 5.6 4.5 1 1 3 5 5 5 4 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB04459.1 - 2.7e-05 24.5 16.2 0.21 12.0 2.9 4.5 2 1 3 5 5 5 5 TNFR/NGFR cysteine-rich region DUF2318 PF10080.9 EGB04459.1 - 0.00044 20.3 12.6 0.0074 16.4 3.5 3.1 1 1 2 3 3 3 2 Predicted membrane protein (DUF2318) Laminin_EGF PF00053.24 EGB04459.1 - 0.027 14.6 21.4 1 9.6 2.3 4.7 1 1 2 3 3 3 0 Laminin EGF domain Sp38 PF07354.12 EGB04459.1 - 0.55 9.6 15.8 0.12 11.8 5.1 3.4 1 1 3 4 4 4 0 Zona-pellucida-binding protein (Sp38) NYD-SP28 PF14772.6 EGB04460.1 - 1.9e-32 111.3 16.6 1.9e-32 111.3 16.6 7.2 6 1 2 8 8 8 1 Sperm tail NYD-SP28_assoc PF14775.6 EGB04460.1 - 1.1e-18 67.1 1.2 1.1e-18 67.1 1.2 5.0 4 1 1 5 5 5 1 Sperm tail C-terminal domain Ribosomal_60s PF00428.19 EGB04460.1 - 0.52 10.9 6.7 0.22 12.1 0.7 3.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C2H2_aberr PF17017.5 EGB04460.1 - 3.3 7.8 5.9 0.78 9.9 1.5 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger Baculo_PEP_C PF04513.12 EGB04460.1 - 5.9 6.9 18.7 0.66 10.0 0.6 4.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serinc PF03348.15 EGB04461.1 - 9e-74 248.9 6.5 1.2e-73 248.5 6.5 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Gly_transf_sug PF04488.15 EGB04465.1 - 0.0003 21.4 0.1 0.00057 20.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FYVE PF01363.21 EGB04466.1 - 4.7e-12 45.9 18.5 5.1e-12 45.8 18.5 1.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGB04466.1 - 1 9.6 9.4 1.2 9.4 9.4 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 EGB04466.1 - 3 8.1 16.1 3.6 7.8 12.7 2.5 1 1 0 1 1 1 0 B-box zinc finger FAD_binding_4 PF01565.23 EGB04467.1 - 1.3e-29 102.7 1.1 3.2e-29 101.4 1.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGB04467.1 - 1.2e-06 28.5 0.0 2.9e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Berberine and berberine like Sulfatase PF00884.23 EGB04468.1 - 3.8e-54 184.2 0.0 5e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB04468.1 - 1.5e-07 31.4 0.1 0.013 15.1 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGB04468.1 - 0.0064 15.2 0.0 0.0092 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Arrestin_C PF02752.22 EGB04469.1 - 7.1e-11 42.7 0.0 1.8e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGB04469.1 - 2.1e-10 40.8 0.0 3.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Cytochrom_C PF00034.21 EGB04470.1 - 1.9e-10 41.8 2.7 1.1e-09 39.3 2.7 1.8 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGB04470.1 - 6.9e-05 23.1 4.9 0.00057 20.2 4.9 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGB04470.1 - 0.026 14.2 0.2 0.051 13.3 0.2 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 EGB04470.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 CCP_MauG PF03150.14 EGB04470.1 - 0.076 13.7 0.0 0.083 13.5 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Ish1 PF10281.9 EGB04470.1 - 0.24 11.7 1.4 12 6.3 0.4 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein C2 PF00168.30 EGB04471.1 - 2.7e-108 355.2 0.0 1.3e-20 73.6 0.0 7.8 8 0 0 8 8 8 6 C2 domain LRR_6 PF13516.6 EGB04471.1 - 1.5e-23 80.8 20.3 0.027 14.5 0.0 11.0 11 0 0 11 11 11 7 Leucine Rich repeat GYF_2 PF14237.6 EGB04471.1 - 1.1e-13 50.7 0.3 6.4e-10 38.7 0.2 2.8 2 0 0 2 2 2 2 GYF domain 2 LRR_4 PF12799.7 EGB04471.1 - 4.5e-06 26.9 0.0 0.0077 16.6 0.0 5.1 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB04471.1 - 1.4e-05 24.7 1.5 0.019 14.7 0.0 4.2 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 EGB04471.1 - 2.8e-05 24.1 0.0 24 6.0 0.0 6.2 6 0 0 6 6 6 2 Leucine Rich Repeat MORN PF02493.20 EGB04472.1 - 9.4e-50 163.6 34.6 9.9e-06 25.2 0.0 13.4 13 1 0 13 13 13 11 MORN repeat DUF3048_C PF17479.2 EGB04472.1 - 0.2 12.0 4.6 35 4.8 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain SRP54 PF00448.22 EGB04473.1 - 5.7e-57 192.5 0.4 1.4e-33 116.2 0.0 2.2 1 1 1 2 2 2 2 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EGB04473.1 - 1.5e-06 28.3 0.0 6e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 EGB04473.1 - 1.5e-05 25.5 2.7 1.5e-05 25.5 2.7 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EGB04473.1 - 0.00024 20.9 1.8 0.00041 20.1 0.5 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 EGB04473.1 - 0.00069 20.0 1.7 0.00098 19.5 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EGB04473.1 - 0.0012 19.1 0.0 0.0093 16.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGB04473.1 - 0.0037 17.0 0.0 0.033 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EGB04473.1 - 0.011 15.7 0.0 0.038 14.0 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 EGB04473.1 - 0.017 15.4 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGB04473.1 - 0.018 14.3 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 EGB04473.1 - 0.026 14.7 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 EGB04473.1 - 0.04 13.8 0.1 0.088 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB04473.1 - 0.051 13.5 0.1 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Barstar PF01337.18 EGB04473.1 - 0.053 13.5 0.9 0.65 10.1 0.1 2.7 3 0 0 3 3 3 0 Barstar (barnase inhibitor) ABC_tran PF00005.27 EGB04473.1 - 0.098 13.2 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Fer4_NifH PF00142.18 EGB04473.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA PF00004.29 EGB04473.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EGB04473.1 - 0.11 11.4 0.3 0.18 10.6 0.3 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Ric8 PF10165.9 EGB04474.1 - 1.3e-15 57.4 0.0 5.9e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Guanine nucleotide exchange factor synembryn Arm PF00514.23 EGB04474.1 - 0.28 11.3 0.0 0.28 11.3 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 EGB04475.1 - 1.5e-31 109.6 0.0 3.7e-31 108.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB04475.1 - 4.4e-30 104.9 0.0 6.4e-30 104.4 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGB04475.1 - 0.078 12.9 0.1 0.39 10.6 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EGB04475.1 - 0.14 11.5 0.1 0.25 10.7 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NLPC_P60 PF00877.19 EGB04476.1 - 0.02 14.9 0.1 0.048 13.7 0.1 1.6 1 1 0 1 1 1 0 NlpC/P60 family Ion_trans PF00520.31 EGB04477.1 - 1.2e-41 142.6 19.5 6e-25 87.9 5.2 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 EGB04477.1 - 0.00078 19.8 0.2 0.0073 16.7 0.2 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB04477.1 - 0.04 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EGB04477.1 - 0.085 12.4 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 EF hand EamA PF00892.20 EGB04478.1 - 2.4e-12 47.2 14.2 3.6e-09 36.9 1.9 2.5 2 0 0 2 2 2 2 EamA-like transporter family Methyltransf_32 PF13679.6 EGB04480.1 - 2.3e-07 31.0 1.8 9.6e-07 28.9 1.8 1.9 1 1 0 1 1 1 1 Methyltransferase domain Patched PF02460.18 EGB04480.1 - 3.1e-07 28.9 7.8 4.5e-07 28.4 7.8 1.2 1 0 0 1 1 1 1 Patched family MMPL PF03176.15 EGB04480.1 - 0.0018 17.2 9.1 0.0033 16.4 9.1 1.3 1 0 0 1 1 1 1 MMPL family MTS PF05175.14 EGB04480.1 - 0.0048 16.5 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB04480.1 - 0.016 15.9 0.0 0.042 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GSHPx PF00255.19 EGB04481.1 - 5e-29 100.0 0.0 1.5e-28 98.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EGB04481.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family DnaJ_C PF01556.18 EGB04482.1 - 5.1e-34 117.5 0.1 9.5e-34 116.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB04482.1 - 5.7e-20 71.2 0.5 9.3e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain MFS_5 PF05631.14 EGB04483.1 - 1.9e-62 211.2 8.0 2.5e-62 210.8 8.0 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGB04483.1 - 3.3e-13 49.3 43.1 3.3e-13 49.3 43.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Adenylsucc_synt PF00709.21 EGB04484.1 - 4.8e-161 536.4 0.0 5.7e-161 536.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase HALZ PF02183.18 EGB04485.1 - 0.083 13.1 1.4 0.72 10.1 0.3 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Myb_DNA-binding PF00249.31 EGB04485.1 - 0.14 12.4 0.5 17 5.7 0.0 3.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain Lin0512_fam PF09585.10 EGB04486.1 - 1.2e-33 115.6 0.0 1.3e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) dCMP_cyt_deam_1 PF00383.23 EGB04487.1 - 2e-25 88.6 0.1 2.8e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGB04487.1 - 1.7e-18 66.7 0.0 2.5e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 EGB04487.1 - 0.059 13.5 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 ABC_tran PF00005.27 EGB04488.1 - 7.5e-24 84.8 0.0 9.6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB04488.1 - 1.6e-07 31.5 0.0 0.00092 19.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB04488.1 - 5.8e-05 22.6 0.0 0.01 15.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB04488.1 - 7.4e-05 22.4 1.4 0.00047 19.8 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB04488.1 - 0.0011 18.9 0.3 0.0021 18.0 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EGB04488.1 - 0.03 14.8 0.2 0.042 14.3 0.2 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB04488.1 - 0.038 14.4 0.3 0.05 14.0 0.3 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGB04488.1 - 0.044 13.3 0.2 0.089 12.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGB04488.1 - 0.079 13.2 0.1 0.36 11.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGB04488.1 - 0.19 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGB04488.1 - 0.21 11.7 0.3 0.42 10.7 0.3 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase LNS2 PF08235.13 EGB04489.1 - 1.1e-39 136.2 0.0 1.7e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGB04489.1 - 2e-06 27.7 0.1 8e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 lipin, N-terminal conserved region Pkinase PF00069.25 EGB04491.1 - 1.1e-20 74.1 0.0 2.4e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04491.1 - 2.3e-13 50.1 0.0 7.6e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PDEase_I PF00233.19 EGB04492.1 - 3.4e-65 220.1 0.0 4e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Glyco_hydro_31 PF01055.26 EGB04493.1 - 2.1e-28 99.7 0.0 3.1e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Voltage_CLC PF00654.20 EGB04494.1 - 6.3e-14 52.0 6.5 7.8e-14 51.7 6.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel U-box PF04564.15 EGB04495.1 - 5.5e-16 58.5 0.0 8.9e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain HATPase_c_3 PF13589.6 EGB04495.1 - 5.5e-06 26.3 0.6 0.12 12.2 0.0 3.1 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UBA PF00627.31 EGB04495.1 - 0.033 14.1 0.1 0.033 14.1 0.1 2.9 2 0 0 2 2 2 0 UBA/TS-N domain UbiA PF01040.18 EGB04496.1 - 1e-24 87.2 25.5 1.8e-24 86.4 25.5 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family NAD_binding_1 PF00175.21 EGB04497.1 - 5.3e-17 62.4 0.0 8.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 EGB04497.1 - 2e-09 37.3 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 EGB04497.1 - 0.064 13.4 0.0 0.43 10.7 0.0 2.1 1 1 0 2 2 2 0 Ferric reductase NAD binding domain DUF3787 PF12655.7 EGB04497.1 - 0.36 10.8 1.1 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) YtxH PF12732.7 EGB04497.1 - 0.54 10.8 3.0 12 6.5 0.1 2.4 2 0 0 2 2 2 0 YtxH-like protein ADH_zinc_N PF00107.26 EGB04498.1 - 2.2e-17 63.2 1.5 2.6e-17 63.0 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGB04498.1 - 1.3e-13 50.8 0.0 2.2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGB04498.1 - 2.6e-06 28.5 0.1 1.4e-05 26.1 0.1 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase SAC3_GANP PF03399.16 EGB04499.1 - 3.2e-24 85.8 0.0 4.4e-22 78.8 0.0 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGB04499.1 - 2.6e-09 37.2 0.0 3.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HTH_18 PF12833.7 EGB04499.1 - 0.14 12.5 0.3 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain ATP-synt_C PF00137.21 EGB04501.1 - 6.3e-35 119.3 37.2 4.4e-23 81.4 16.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C EGF_2 PF07974.13 EGB04504.1 - 1.7e-15 57.1 56.4 7.8e-06 26.2 5.3 5.3 5 0 0 5 5 5 5 EGF-like domain EGF PF00008.27 EGB04504.1 - 0.0036 17.6 8.0 0.013 15.8 3.0 5.9 6 0 0 6 6 6 3 EGF-like domain Laminin_EGF PF00053.24 EGB04504.1 - 0.0039 17.3 45.6 0.046 13.9 5.1 4.5 3 2 1 4 4 4 3 Laminin EGF domain TMF_TATA_bd PF12325.8 EGB04505.1 - 6.6e-05 23.1 6.2 0.086 13.1 0.9 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Alpha-2-MRAP_C PF06401.11 EGB04505.1 - 0.014 15.4 7.9 0.018 15.0 7.9 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Seryl_tRNA_N PF02403.22 EGB04505.1 - 0.034 14.4 9.9 0.11 12.8 0.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mt_ATP-synt_D PF05873.12 EGB04505.1 - 0.037 13.9 1.8 0.056 13.3 1.8 1.3 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1515 PF07439.11 EGB04505.1 - 0.055 13.5 0.6 0.11 12.5 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Phage_GP20 PF06810.11 EGB04505.1 - 0.057 13.2 5.9 0.18 11.6 5.8 2.1 1 1 0 1 1 1 0 Phage minor structural protein GP20 TSC22 PF01166.18 EGB04505.1 - 0.1 12.9 0.4 0.1 12.9 0.4 2.9 3 1 0 3 3 3 0 TSC-22/dip/bun family Lebercilin PF15619.6 EGB04505.1 - 0.1 12.2 10.2 0.36 10.5 1.4 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 EGB04505.1 - 0.17 12.1 13.5 0.099 12.9 3.8 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 EGB04505.1 - 0.18 11.9 9.3 0.59 10.2 2.3 2.6 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DHR10 PF18595.1 EGB04505.1 - 0.18 11.8 8.8 0.12 12.5 0.6 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FlxA PF14282.6 EGB04505.1 - 0.25 11.4 7.1 2.7 8.0 1.9 2.3 2 0 0 2 2 2 0 FlxA-like protein APG6_N PF17675.1 EGB04505.1 - 0.36 11.4 11.2 0.93 10.0 4.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Com_YlbF PF06133.11 EGB04505.1 - 0.4 11.3 12.3 1.7 9.3 3.4 2.2 1 1 2 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DUF4407 PF14362.6 EGB04505.1 - 0.5 9.7 4.7 0.74 9.1 4.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 EGB04505.1 - 0.84 10.1 14.2 1.6 9.1 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3461 PF11944.8 EGB04505.1 - 2 8.5 8.5 0.55 10.4 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) ZapB PF06005.12 EGB04505.1 - 2.9 8.4 12.2 9.4 6.8 3.9 2.8 2 2 0 2 2 2 0 Cell division protein ZapB BST2 PF16716.5 EGB04506.1 - 0.011 16.3 18.7 0.83 10.3 0.7 3.2 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Uso1_p115_C PF04871.13 EGB04506.1 - 0.025 14.9 16.0 0.095 13.1 2.4 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ERM PF00769.19 EGB04506.1 - 0.026 14.3 25.1 1.1 9.0 3.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ArAE_2_N PF10337.9 EGB04506.1 - 0.037 13.1 4.5 0.039 13.0 4.5 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal UPF0242 PF06785.11 EGB04506.1 - 0.049 13.7 20.0 0.047 13.8 18.2 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 EGB04506.1 - 0.48 10.1 10.6 0.77 9.5 10.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Occludin_ELL PF07303.13 EGB04506.1 - 0.58 10.9 13.8 1 10.1 0.4 3.1 1 1 2 3 3 3 0 Occludin homology domain Spc7 PF08317.11 EGB04506.1 - 1 8.2 16.3 1.7 7.5 16.3 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 EGB04506.1 - 1.1 9.4 20.6 4.2 7.6 1.6 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) OmpH PF03938.14 EGB04506.1 - 1.2 9.4 23.2 0.065 13.6 1.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HAUS6_N PF14661.6 EGB04506.1 - 1.4 8.5 17.1 0.024 14.2 2.0 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Phage_lysis PF03245.13 EGB04506.1 - 1.7 8.8 11.7 1.5 9.0 5.3 3.0 1 1 0 3 3 3 0 Bacteriophage Rz lysis protein Bap31_Bap29_C PF18035.1 EGB04506.1 - 2 8.5 8.3 0.95 9.5 0.3 3.3 2 1 2 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Peptidase_S46 PF10459.9 EGB04506.1 - 2.7 6.5 11.9 3.3 6.2 11.9 1.0 1 0 0 1 1 1 0 Peptidase S46 FUSC PF04632.12 EGB04506.1 - 2.8 6.3 4.9 3.8 5.9 4.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRE1 PF08647.11 EGB04506.1 - 3.1 7.9 18.6 2.8 8.1 10.8 2.6 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2203 PF09969.9 EGB04506.1 - 4.7 7.9 10.9 1.5 9.6 1.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 EGB04506.1 - 6.3 5.3 15.8 0.18 10.4 1.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A NAC PF01849.18 EGB04507.1 - 6.3e-23 80.5 0.1 1.2e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 NAC domain WD40 PF00400.32 EGB04508.1 - 8.1e-19 67.6 8.9 7.7e-09 36.1 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04508.1 - 0.0033 17.7 0.1 0.11 12.8 0.0 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB04508.1 - 0.19 10.3 2.5 1.5 7.3 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Methyltransf_3 PF01596.17 EGB04508.1 - 0.2 10.8 0.0 1.8 7.7 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase cobW PF02492.19 EGB04509.1 - 8.6e-42 142.7 0.0 1.2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGB04509.1 - 0.0028 17.7 0.0 0.0068 16.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGB04509.1 - 0.0031 17.7 0.0 0.007 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB04509.1 - 0.011 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB04509.1 - 0.029 14.3 0.0 0.093 12.6 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EGB04509.1 - 0.032 13.8 0.0 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.14 EGB04509.1 - 0.075 12.9 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4407 PF14362.6 EGB04509.1 - 0.098 12.0 1.9 0.14 11.5 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cullin PF00888.22 EGB04510.1 - 1.5e-40 139.5 0.2 1.7e-40 139.3 0.2 1.0 1 0 0 1 1 1 1 Cullin family Cullin PF00888.22 EGB04511.1 - 8.8e-65 219.5 0.0 1.5e-64 218.7 0.0 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGB04511.1 - 1.2e-27 95.7 0.6 1.2e-27 95.7 0.6 1.7 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 EGB04511.1 - 0.0038 17.5 0.1 0.15 12.4 0.0 2.4 2 0 0 2 2 2 1 Penicillinase repressor Frataxin_Cyay PF01491.16 EGB04512.1 - 3.6e-29 101.0 0.0 4.7e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain VHS PF00790.19 EGB04513.1 - 1.3e-24 86.6 0.0 1.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EGB04513.1 - 0.00082 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 GAT domain AAA PF00004.29 EGB04514.1 - 8.3e-66 220.4 0.0 4.5e-44 150.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB04514.1 - 4.6e-20 71.2 4.7 1.4e-11 44.0 0.4 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGB04514.1 - 3e-14 53.8 0.2 7.6e-05 23.2 0.0 4.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGB04514.1 - 3.3e-08 33.9 0.2 0.019 15.3 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGB04514.1 - 1.2e-07 31.9 0.3 0.00044 20.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGB04514.1 - 1.5e-07 31.3 0.0 0.00063 19.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGB04514.1 - 3e-07 30.7 0.0 0.0013 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGB04514.1 - 2.7e-06 26.9 0.7 0.039 13.3 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGB04514.1 - 1.3e-05 25.6 0.0 0.07 13.5 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EGB04514.1 - 2.8e-05 24.7 0.1 0.1 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EGB04514.1 - 3.1e-05 23.8 0.1 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 EGB04514.1 - 4.9e-05 23.3 0.0 0.023 14.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGB04514.1 - 7.2e-05 22.8 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB04514.1 - 0.0001 22.3 0.1 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Viral_helicase1 PF01443.18 EGB04514.1 - 0.00019 21.3 0.1 0.37 10.5 0.2 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EGB04514.1 - 0.00025 21.4 0.1 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGB04514.1 - 0.00025 20.3 0.1 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 EGB04514.1 - 0.00031 20.9 0.0 0.0051 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 EGB04514.1 - 0.00044 19.7 0.0 0.56 9.5 0.0 2.3 2 0 0 2 2 2 2 KaiC ABC_tran PF00005.27 EGB04514.1 - 0.00047 20.7 0.1 1.1 9.7 0.0 2.8 2 1 1 3 3 3 1 ABC transporter Sigma54_activat PF00158.26 EGB04514.1 - 0.001 18.8 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGB04514.1 - 0.0011 18.3 0.2 0.21 10.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 EGB04514.1 - 0.0013 18.5 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGB04514.1 - 0.0014 18.3 2.6 0.32 10.6 0.0 3.4 3 1 1 4 4 4 1 AAA domain AAA_11 PF13086.6 EGB04514.1 - 0.0016 18.3 0.0 1.5 8.5 0.0 2.4 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EGB04514.1 - 0.0025 17.7 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGB04514.1 - 0.0025 17.8 0.0 0.59 10.0 0.0 2.4 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EGB04514.1 - 0.0037 16.5 0.0 0.98 8.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 EGB04514.1 - 0.0039 17.1 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EGB04514.1 - 0.0072 15.9 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region PhoH PF02562.16 EGB04514.1 - 0.014 14.9 0.7 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.6 EGB04514.1 - 0.015 15.7 0.3 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGB04514.1 - 0.069 13.5 0.4 20 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGB04514.1 - 0.078 12.1 0.0 0.61 9.1 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DAP3 PF10236.9 EGB04514.1 - 0.11 11.6 0.0 2.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Vps4_C PF09336.10 EGB04514.1 - 0.12 12.4 0.0 0.8 9.8 0.0 2.3 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.15 EGB04514.1 - 0.2 11.5 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 EGB04514.1 - 0.25 11.1 0.0 24 4.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EGB04514.1 - 0.29 10.8 6.4 5.6 6.6 0.0 3.5 5 0 0 5 5 4 0 AAA domain DUF2075 PF09848.9 EGB04514.1 - 0.34 10.1 0.2 14 4.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Nuc_sug_transp PF04142.15 EGB04515.1 - 1.5e-100 336.4 7.5 1.8e-100 336.2 7.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB04515.1 - 1.5e-06 28.4 18.1 1.6e-05 25.1 4.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 EGB04515.1 - 0.0013 18.4 0.3 0.0021 17.7 0.3 1.5 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter UAA PF08449.11 EGB04515.1 - 0.0014 17.9 0.9 0.0024 17.1 0.7 1.6 1 1 0 1 1 1 1 UAA transporter family DUF1761 PF08570.10 EGB04515.1 - 0.54 10.5 7.8 12 6.1 2.3 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1761) Sel1 PF08238.12 EGB04516.1 - 1.1e-18 67.2 18.1 0.0034 18.0 0.0 7.3 7 0 0 7 7 7 5 Sel1 repeat zf-MYND PF01753.18 EGB04516.1 - 1.6e-08 34.5 13.8 1.6e-08 34.5 13.8 3.5 2 1 1 3 3 3 1 MYND finger Spore_YtrH PF14034.6 EGB04516.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YtrH 2OG-FeII_Oxy_3 PF13640.6 EGB04517.1 - 2e-15 57.5 0.0 9.4e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WW PF00397.26 EGB04517.1 - 1.9e-06 27.8 0.1 3.6e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 WW domain 2OG-FeII_Oxy_4 PF13661.6 EGB04517.1 - 3.9e-06 27.4 0.0 1.2e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_5 PF13202.6 EGB04517.1 - 0.00031 20.1 0.2 0.00082 18.8 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGB04517.1 - 0.024 14.5 0.2 0.079 12.9 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EGB04517.1 - 0.037 14.5 0.1 0.13 12.7 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EGB04517.1 - 0.11 12.1 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 EF hand Arm PF00514.23 EGB04517.1 - 0.28 11.3 7.9 0.11 12.6 0.1 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SNARE PF05739.19 EGB04519.1 - 1.2e-13 50.8 0.1 2.3e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 SNARE domain MCPsignal PF00015.21 EGB04519.1 - 0.0019 18.0 0.3 0.0052 16.6 0.3 1.7 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.25 EGB04519.1 - 0.0068 16.1 0.5 0.0068 16.1 0.5 2.2 2 0 0 2 2 2 1 Syntaxin RCC1 PF00415.18 EGB04521.1 - 8.2e-48 160.8 25.9 2.5e-08 34.4 1.6 7.1 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB04521.1 - 2.7e-36 122.7 23.3 3.1e-07 30.0 0.0 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat 7kD_DNA_binding PF02294.18 EGB04521.1 - 0.03 14.3 0.3 4 7.5 0.0 3.2 4 0 0 4 4 4 0 7kD DNA-binding domain EF1G PF00647.19 EGB04522.1 - 1e-36 125.2 0.4 2e-36 124.3 0.4 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGB04522.1 - 3.9e-16 59.2 0.0 8.5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB04522.1 - 2.8e-12 46.7 1.0 4.4e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB04522.1 - 2.5e-09 37.0 0.2 6.6e-09 35.7 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB04522.1 - 4e-09 36.8 0.0 1e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB04522.1 - 3.2e-07 30.5 0.0 6.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB04522.1 - 1.4e-06 28.4 0.0 4.3e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 EGB04522.1 - 0.00058 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cpn60_TCP1 PF00118.24 EGB04524.1 - 1.6e-90 304.1 3.1 2.8e-90 303.3 3.1 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FG-GAP PF01839.23 EGB04525.1 - 1.2e-16 60.5 27.1 6.3e-06 26.2 8.5 3.7 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 EGB04525.1 - 2.3e-08 34.5 32.8 1.8e-05 25.2 9.5 3.2 1 1 3 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EGB04525.1 - 2.8 7.3 9.0 7.4 5.9 0.4 3.3 2 1 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region Ras PF00071.22 EGB04526.1 - 1.2e-19 70.5 0.0 1.4e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB04526.1 - 4.5e-17 62.4 0.0 5.6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGB04526.1 - 0.00019 21.5 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EGB04526.1 - 0.00032 20.2 0.0 0.00039 19.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_25 PF13481.6 EGB04526.1 - 0.0062 16.1 0.1 0.0072 15.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB04526.1 - 0.0072 16.7 0.1 0.0095 16.3 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGB04526.1 - 0.035 13.6 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGB04526.1 - 0.045 13.5 0.0 0.059 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB04526.1 - 0.048 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EGB04526.1 - 0.061 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB04526.1 - 0.068 13.4 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB04526.1 - 0.069 13.1 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EGB04526.1 - 0.073 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 EGB04526.1 - 0.081 12.0 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain Gtr1_RagA PF04670.12 EGB04526.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGB04526.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 EGB04526.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) UPF0113_N PF17833.1 EGB04527.1 - 8.3e-19 67.9 0.0 1e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain ABC_tran PF00005.27 EGB04528.1 - 6.1e-19 68.9 0.0 7.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGB04528.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB04528.1 - 0.0018 18.7 1.5 0.0053 17.1 1.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGB04528.1 - 0.0062 16.8 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGB04528.1 - 0.011 15.6 0.1 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB04528.1 - 0.014 15.3 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGB04528.1 - 0.028 15.0 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGB04528.1 - 0.074 13.0 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 EGB04528.1 - 0.077 13.2 0.9 0.16 12.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGB04528.1 - 0.078 12.6 1.6 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGB04528.1 - 0.19 11.8 0.1 0.28 11.2 0.1 1.2 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 EGB04528.1 - 0.2 10.7 0.1 0.31 10.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EGB04528.1 - 0.25 11.8 0.0 0.36 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arylsulfotrans PF05935.11 EGB04529.1 - 0.068 12.1 0.0 4.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) K_oxygenase PF13434.6 EGB04530.1 - 0.00094 18.4 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF3992 PF13157.6 EGB04530.1 - 0.032 14.9 0.0 0.12 13.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) Pyr_redox_3 PF13738.6 EGB04530.1 - 0.076 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase eRF1_2 PF03464.15 EGB04531.1 - 1.8e-44 151.3 0.0 3.2e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGB04531.1 - 5.6e-34 117.0 0.2 1.1e-33 116.1 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGB04531.1 - 4.1e-19 68.9 0.0 7.4e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EGB04531.1 - 1.4e-09 38.3 0.1 2.5e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EGB04531.1 - 1.8e-07 31.5 0.0 3.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 RRM_1 PF00076.22 EGB04532.1 - 0.00036 20.3 0.0 0.4 10.5 0.0 3.5 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 EGB04532.1 - 0.0045 16.8 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 EGB04532.1 - 0.024 14.4 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain NODP PF07684.12 EGB04532.1 - 0.23 11.6 2.1 0.22 11.7 0.3 1.9 2 0 0 2 2 2 0 NOTCH protein DUF2475 PF10629.9 EGB04533.1 - 0.0055 16.9 1.8 3.5 7.9 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2475) SPATA48 PF15073.6 EGB04533.1 - 0.0095 16.2 0.1 0.025 14.9 0.1 1.7 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 DUF1126 PF06565.12 EGB04535.1 - 3.8e-58 193.8 0.6 3.6e-22 78.2 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain PXA PF02194.15 EGB04536.1 - 1.2e-21 77.5 0.0 2.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 PXA domain PX PF00787.24 EGB04536.1 - 1.3e-10 41.2 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 PX domain Nexin_C PF08628.12 EGB04536.1 - 3.2e-06 27.7 0.0 8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Sorting nexin C terminal MIP-T3 PF10243.9 EGB04537.1 - 5.9e-62 206.6 0.6 4.5e-36 123.3 0.0 2.7 2 1 0 2 2 2 2 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 EGB04537.1 - 2.6e-30 105.4 5.2 2.6e-30 105.4 5.2 1.8 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region TPR_2 PF07719.17 EGB04537.1 - 4e-27 92.1 9.7 0.0057 16.7 0.4 9.0 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04537.1 - 9.2e-23 79.1 5.5 0.014 15.2 0.2 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_9 PF13371.6 EGB04537.1 - 7e-12 45.3 14.1 0.014 15.6 0.2 6.7 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB04537.1 - 5.5e-10 39.7 13.1 0.32 11.7 0.0 7.4 5 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB04537.1 - 6.1e-10 38.6 0.1 1.4 8.7 0.0 7.7 6 2 2 8 8 8 3 TPR repeat TPR_19 PF14559.6 EGB04537.1 - 9.7e-09 35.6 6.7 0.0019 18.6 0.1 5.8 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB04537.1 - 2.2e-08 33.7 0.0 5 7.6 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB04537.1 - 4.9e-08 33.2 20.5 1.9 9.5 0.0 9.7 7 2 3 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB04537.1 - 0.0012 19.1 11.3 15 5.9 0.1 6.9 4 3 2 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB04537.1 - 0.006 17.1 1.3 54 4.7 0.0 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB04537.1 - 0.013 15.6 0.2 0.97 9.6 0.0 3.1 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat UPF0242 PF06785.11 EGB04537.1 - 0.73 9.9 6.7 1.9 8.5 6.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 EGB04537.1 - 3.4 8.2 6.0 7.7 7.1 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Polyketide_cyc2 PF10604.9 EGB04538.1 - 1.2e-06 28.8 0.0 2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Radial_spoke PF04712.12 EGB04539.1 - 1.8e-94 317.5 0.9 6.1e-66 223.4 0.5 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein MFS_1 PF07690.16 EGB04540.1 - 4.5e-14 52.1 14.8 5.4e-14 51.9 14.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EGB04540.1 - 0.00027 19.4 5.9 0.00027 19.4 5.9 1.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EGB04540.1 - 0.18 10.6 13.0 0.22 10.4 13.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Pkinase PF00069.25 EGB04541.1 - 2.5e-42 145.1 0.0 2.9e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04541.1 - 1.7e-23 83.2 0.0 2.2e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB04541.1 - 0.0018 17.6 0.4 0.0035 16.7 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB04541.1 - 0.0097 15.8 0.1 0.066 13.1 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB04541.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGB04541.1 - 0.04 12.7 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EGB04541.1 - 0.045 13.3 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EGB04541.1 - 0.17 10.8 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EGB04541.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2451 PF10474.9 EGB04542.1 - 3.8e-28 98.9 0.0 4.3e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Pkinase PF00069.25 EGB04543.1 - 1.5e-56 191.7 0.0 1.7e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04543.1 - 7.7e-42 143.4 0.0 9.6e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04543.1 - 7e-05 22.3 0.0 0.00017 21.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGB04543.1 - 0.12 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGB04543.1 - 0.23 11.4 0.0 0.45 10.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family SPT16 PF08644.11 EGB04544.1 - 1.4e-30 106.5 1.1 2.2e-30 105.9 0.2 1.9 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 EGB04544.1 - 4.6e-16 59.0 0.1 9.3e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PPP4R2 PF09184.11 EGB04544.1 - 0.94 9.0 24.5 1.8 8.1 24.5 1.5 1 0 0 1 1 1 0 PPP4R2 SpoIIIAH PF12685.7 EGB04544.1 - 2.7 7.8 10.7 4.4 7.1 10.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF733 PF05306.11 EGB04544.1 - 2.9 8.3 6.5 32 4.9 6.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF733) SDA1 PF05285.12 EGB04544.1 - 4.5 6.6 32.5 8 5.8 32.5 1.3 1 0 0 1 1 1 0 SDA1 Pantoate_transf PF02548.15 EGB04545.1 - 7e-103 343.5 0.2 7.8e-103 343.4 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 EGB04545.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase AAA PF00004.29 EGB04546.1 - 4.4e-38 130.7 0.0 4.7e-37 127.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB04546.1 - 2.5e-07 30.4 0.4 6.2e-07 29.1 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGB04546.1 - 3e-07 31.0 0.1 0.0011 19.4 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB04546.1 - 0.0011 19.2 0.0 0.037 14.3 0.0 2.9 3 1 1 4 4 4 1 AAA domain RuvB_N PF05496.12 EGB04546.1 - 0.0021 17.8 0.0 0.0092 15.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGB04546.1 - 0.0069 16.4 0.1 0.096 12.7 0.0 2.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGB04546.1 - 0.0099 16.4 0.0 0.13 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB04546.1 - 0.015 15.2 0.0 0.15 11.9 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 EGB04546.1 - 0.018 14.7 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGB04546.1 - 0.022 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 EGB04546.1 - 0.034 14.1 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGB04546.1 - 0.04 13.8 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB04546.1 - 0.045 14.1 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EGB04546.1 - 0.045 13.9 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGB04546.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EGB04546.1 - 0.11 12.2 0.0 0.74 9.6 0.0 2.1 2 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.15 EGB04546.1 - 0.19 11.6 0.0 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 NTPase Cyt-b5 PF00173.28 EGB04547.1 - 2.3e-06 27.7 0.0 4.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2604 PF10790.9 EGB04547.1 - 0.12 12.7 0.0 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF2604) Cyclin PF08613.11 EGB04548.1 - 3.7e-20 72.9 1.1 3.9e-20 72.8 1.1 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGB04548.1 - 5e-09 36.0 0.2 5.6e-09 35.8 0.2 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Thoc2 PF11732.8 EGB04548.1 - 0.056 13.5 0.7 0.2 11.7 0.1 1.9 1 1 1 2 2 2 0 Transcription- and export-related complex subunit AAA_21 PF13304.6 EGB04549.1 - 8.2e-08 32.4 0.0 1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EGB04549.1 - 3.1e-05 24.5 0.0 5.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 EGB04549.1 - 0.0014 18.8 0.1 0.27 11.5 0.0 2.5 2 1 1 3 3 3 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EGB04549.1 - 0.078 12.4 0.0 0.092 12.2 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Exostosin PF03016.15 EGB04550.1 - 2.9e-22 79.2 0.4 1.3e-21 77.1 0.4 1.9 1 1 0 1 1 1 1 Exostosin family Ribonuclease_3 PF00636.26 EGB04550.1 - 0.15 12.7 0.0 1.4 9.6 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease III domain Methyltransf_16 PF10294.9 EGB04551.1 - 7.7e-18 64.8 0.0 9.7e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGB04551.1 - 0.001 19.8 0.0 0.0014 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB04551.1 - 0.0021 17.9 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB04551.1 - 0.0098 16.6 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB04551.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GidB PF02527.15 EGB04551.1 - 0.029 13.7 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RNA_pol_I_A49 PF06870.12 EGB04552.1 - 3.6e-29 101.8 0.0 1.8e-28 99.5 0.0 1.8 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor HMG_box PF00505.19 EGB04553.1 - 3.5e-12 46.5 0.3 1.7e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box Dynamin_N PF00350.23 EGB04553.1 - 2.6e-09 37.4 0.0 1e-08 35.4 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB04553.1 - 1e-05 25.5 0.0 0.00011 22.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase HMG_box_2 PF09011.10 EGB04553.1 - 0.0015 19.1 0.0 0.0034 17.9 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain RsgA_GTPase PF03193.16 EGB04553.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGB04553.1 - 0.0081 16.7 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB04553.1 - 0.14 12.6 2.8 1 9.8 0.0 4.1 4 0 0 4 4 4 0 AAA ATPase domain AIG1 PF04548.16 EGB04553.1 - 0.21 10.9 0.1 0.36 10.1 0.1 1.3 1 0 0 1 1 1 0 AIG1 family LRR_6 PF13516.6 EGB04554.1 - 6.3e-17 60.1 9.4 0.0027 17.6 0.1 7.3 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 EGB04554.1 - 4e-06 26.6 0.5 8.6 7.3 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 EGB04554.1 - 4.8e-06 26.8 4.7 1.3 9.5 0.1 4.8 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB04554.1 - 0.0058 16.4 5.1 8.4 6.2 0.2 4.8 4 0 0 4 4 4 2 Leucine rich repeat Ion_trans PF00520.31 EGB04555.1 - 2.8e-122 406.6 76.0 4.3e-42 144.0 19.2 5.2 5 0 0 5 5 5 5 Ion transport protein GPHH PF16905.5 EGB04555.1 - 7.4e-07 28.8 0.0 2.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated WD40 PF00400.32 EGB04555.1 - 0.012 16.5 6.6 0.74 10.8 0.1 4.9 4 0 0 4 4 4 0 WD domain, G-beta repeat ICMT PF04140.14 EGB04555.1 - 0.083 13.3 1.1 0.62 10.5 0.0 3.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4714 PF15833.5 EGB04555.1 - 0.098 12.6 0.8 4.2 7.3 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4714) PQQ_3 PF13570.6 EGB04555.1 - 0.66 10.5 2.0 53 4.5 0.1 3.8 5 0 0 5 5 5 0 PQQ-like domain Exo_endo_phos PF03372.23 EGB04556.1 - 2.5e-14 53.4 6.3 2.1e-13 50.4 6.3 2.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PX PF00787.24 EGB04556.1 - 0.0039 17.2 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 PX domain RRM_1 PF00076.22 EGB04557.1 - 5.2e-21 74.2 0.0 5.7e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB04557.1 - 0.00069 19.4 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGB04557.1 - 0.045 13.8 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PhyH PF05721.13 EGB04558.1 - 2.4e-25 90.1 0.1 2.9e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ion_trans PF00520.31 EGB04559.1 - 2.9e-16 59.4 7.8 4.5e-16 58.8 7.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB04559.1 - 6.3e-11 42.1 4.7 1.7e-10 40.7 4.7 1.7 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGB04559.1 - 1.2e-08 34.9 0.0 3.1e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Hydrolase_4 PF12146.8 EGB04560.1 - 7.7e-11 41.7 0.1 1.2e-08 34.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGB04560.1 - 1.6e-05 25.6 0.0 3.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EGB04560.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGB04560.1 - 0.00039 20.2 0.1 0.0015 18.2 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGB04560.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 EGB04560.1 - 0.14 12.3 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein TPR_11 PF13414.6 EGB04561.1 - 7.1e-67 220.8 48.1 1.3e-09 37.6 0.8 10.6 1 1 10 11 11 11 10 TPR repeat TPR_1 PF00515.28 EGB04561.1 - 3.2e-64 210.3 30.3 9.5e-10 37.9 1.4 10.9 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 EGB04561.1 - 1.1e-59 193.7 31.3 3e-07 30.0 1.1 10.4 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_16 PF13432.6 EGB04561.1 - 1.7e-51 172.6 50.5 2.7e-11 43.9 4.2 6.9 3 3 5 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.6 EGB04561.1 - 4.7e-50 164.4 27.5 2.9e-05 24.1 0.2 11.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGB04561.1 - 6.8e-46 150.7 19.8 2e-08 33.8 0.7 10.4 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 EGB04561.1 - 7.6e-35 116.4 17.1 0.0018 18.1 0.1 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_14 PF13428.6 EGB04561.1 - 3.3e-34 114.6 22.1 0.0038 17.9 1.0 10.4 1 1 9 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 EGB04561.1 - 7.3e-31 106.3 35.1 2.1e-09 37.6 5.5 7.5 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.6 EGB04561.1 - 1.8e-28 98.9 30.3 3.5e-05 24.2 0.2 7.3 2 2 5 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGB04561.1 - 6.9e-25 86.2 42.3 0.00033 20.4 1.3 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_6 PF13174.6 EGB04561.1 - 5e-19 67.6 14.9 0.021 15.4 0.2 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_4 PF07721.14 EGB04561.1 - 4.8e-14 51.5 19.7 0.0097 16.4 0.5 8.8 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGB04561.1 - 3.9e-13 49.4 13.2 0.01 16.0 0.0 6.1 1 1 7 9 9 9 5 Tetratricopeptide repeat BTAD PF03704.17 EGB04561.1 - 1.5e-09 38.4 19.3 0.15 12.5 0.1 5.6 1 1 4 6 6 6 5 Bacterial transcriptional activator domain TPR_20 PF14561.6 EGB04561.1 - 1.7e-08 34.7 21.0 0.12 12.8 0.2 7.0 2 2 4 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGB04561.1 - 8.6e-08 31.7 16.2 0.0063 15.8 0.3 4.7 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_3 PF07720.12 EGB04561.1 - 1.1e-07 31.7 16.3 1 9.4 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_21 PF09976.9 EGB04561.1 - 3.1e-06 27.0 26.3 0.0085 15.8 1.4 6.0 2 1 4 6 6 6 4 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EGB04561.1 - 4.5e-06 26.3 17.0 0.36 10.2 0.1 5.3 1 1 5 6 6 6 4 MalT-like TPR region TPR_5 PF12688.7 EGB04561.1 - 2.7e-05 24.4 12.6 0.013 15.8 0.6 4.7 1 1 4 5 5 5 2 Tetratrico peptide repeat ANAPC3 PF12895.7 EGB04561.1 - 3.3e-05 24.0 21.2 0.028 14.6 2.6 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 EGB04561.1 - 9.8e-05 22.4 8.8 11 6.0 0.0 7.1 2 1 4 8 8 8 0 Domain of Unknown Function (DUF3856) FAT PF02259.23 EGB04561.1 - 0.0017 17.6 3.4 1.1 8.4 0.2 3.2 1 1 1 3 3 3 2 FAT domain Cas3_C PF18395.1 EGB04561.1 - 0.032 14.7 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 1 0 Cas3 C-terminal domain DUF627 PF04781.12 EGB04561.1 - 0.054 13.5 4.1 50 4.0 0.0 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF627) Sec16_C PF12931.7 EGB04561.1 - 0.094 12.3 2.0 0.99 9.0 0.2 2.9 1 1 2 3 3 3 0 Sec23-binding domain of Sec16 Wzy_C_2 PF11846.8 EGB04561.1 - 0.19 11.6 9.8 0.49 10.3 2.4 3.7 2 1 2 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal DUF5344 PF17279.2 EGB04561.1 - 0.27 11.8 1.4 14 6.3 0.0 3.9 3 2 1 4 4 3 0 Family of unknown function (DUF5344) MIT PF04212.18 EGB04561.1 - 0.29 11.3 35.3 0.71 10.0 0.5 7.7 8 1 0 8 8 7 0 MIT (microtubule interacting and transport) domain EST1_DNA_bind PF10373.9 EGB04561.1 - 0.36 10.3 1.7 15 4.9 0.2 2.5 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain Coatomer_E PF04733.14 EGB04561.1 - 0.55 9.6 5.8 3.4 7.0 0.3 3.3 3 1 1 4 4 4 0 Coatomer epsilon subunit MCD_N PF17408.2 EGB04561.1 - 0.63 10.2 5.7 41 4.4 0.2 5.4 2 2 4 6 6 6 0 Malonyl-CoA decarboxylase N-terminal domain DUF5112 PF17139.4 EGB04561.1 - 0.67 9.4 8.2 0.17 11.3 0.6 3.3 2 1 3 5 5 5 0 Domain of unknown function (DUF5112) DUF630 PF04783.12 EGB04561.1 - 1.2 9.4 12.4 2 8.6 0.2 4.9 4 1 1 5 5 4 0 Protein of unknown function (DUF630) CCP_MauG PF03150.14 EGB04561.1 - 9.4 6.9 6.5 1.8e+02 2.7 2.2 3.9 2 1 0 3 3 3 0 Di-haem cytochrome c peroxidase FKBP_C PF00254.28 EGB04562.1 - 1e-16 61.0 0.0 2.4e-09 37.4 0.0 2.5 2 1 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EGB04562.1 - 8.6e-14 50.5 1.7 5e-05 23.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04562.1 - 1.3e-08 34.2 0.8 0.0019 17.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB04562.1 - 7e-08 32.7 4.4 0.00032 21.3 0.4 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB04562.1 - 2.9e-06 27.5 0.6 0.34 11.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB04562.1 - 2.1e-05 25.1 4.0 0.043 14.5 0.3 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB04562.1 - 2.3e-05 24.8 1.3 0.026 15.0 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB04562.1 - 0.00015 21.4 1.1 0.046 13.4 0.2 3.1 3 1 1 4 4 4 1 TPR repeat Fis1_TPR_C PF14853.6 EGB04562.1 - 0.00016 21.7 2.5 0.52 10.4 0.1 3.0 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 EGB04562.1 - 0.0005 20.1 0.0 0.65 10.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB04562.1 - 0.0045 17.2 0.1 0.021 15.1 0.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGB04562.1 - 0.019 15.0 2.1 6.2 7.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB04562.1 - 0.037 14.3 3.3 8.4 6.8 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB04562.1 - 0.075 13.2 3.1 0.43 10.7 1.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.22 EGB04563.1 - 1.2e-41 142.0 0.1 1.4e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB04563.1 - 1e-25 90.3 0.0 1.4e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB04563.1 - 6.5e-13 48.5 0.0 8.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB04563.1 - 4.3e-05 23.6 0.1 5.7e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.11 EGB04563.1 - 0.00021 20.2 0.0 0.00042 19.3 0.0 1.4 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 EGB04563.1 - 0.00026 20.8 0.0 0.0009 19.0 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGB04563.1 - 0.0045 16.4 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGB04563.1 - 0.012 15.9 0.0 0.019 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 EGB04563.1 - 0.018 14.4 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 EGB04563.1 - 0.17 11.3 0.0 2.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AMP-binding PF00501.28 EGB04564.1 - 7.6e-73 245.5 0.0 8.9e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB04564.1 - 3.7e-08 34.2 0.0 1.3e-07 32.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 EGB04565.1 - 3.4e-33 114.5 0.0 4e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB04565.1 - 2.4e-25 89.1 0.1 3.4e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB04565.1 - 7.9e-10 38.5 0.0 8.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB04565.1 - 1.7e-05 24.3 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGB04565.1 - 0.0021 17.6 0.1 0.026 14.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DLIC PF05783.11 EGB04565.1 - 0.0029 16.5 0.6 0.1 11.4 0.0 2.0 1 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) FeoB_N PF02421.18 EGB04565.1 - 0.0059 16.1 0.1 0.058 12.9 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGB04565.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EGB04565.1 - 0.018 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 NTPase G-alpha PF00503.20 EGB04565.1 - 0.026 13.7 0.7 0.23 10.6 0.0 2.3 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 EGB04565.1 - 0.036 13.6 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EGB04565.1 - 0.053 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGB04565.1 - 0.074 12.8 0.5 0.28 10.9 0.5 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EGB04565.1 - 0.087 12.2 0.1 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 EGB04565.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain ERG4_ERG24 PF01222.17 EGB04566.1 - 2.9e-113 378.9 0.0 3.3e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3767 PF12597.8 EGB04566.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Mtc PF03820.17 EGB04567.1 - 1.2e-70 238.1 0.0 2.2e-70 237.2 0.0 1.4 1 1 0 1 1 1 1 Tricarboxylate carrier Cupin_3 PF05899.12 EGB04568.1 - 1.1e-14 53.8 1.7 6.1e-13 48.3 1.7 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EGB04568.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Cupin domain EutQ PF06249.12 EGB04568.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Nucleoporin_FG PF13634.6 EGB04568.1 - 0.13 13.1 2.4 0.17 12.7 0.3 2.2 3 0 0 3 3 3 0 Nucleoporin FG repeat region Rod_cone_degen PF15201.6 EGB04569.1 - 1.2 9.2 5.0 4 7.6 0.1 3.1 2 0 0 2 2 2 0 Progressive rod-cone degeneration Myb_DNA-binding PF00249.31 EGB04570.1 - 8.3e-16 57.9 0.5 9.2e-16 57.8 0.5 1.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB04570.1 - 1e-07 32.1 0.4 1.1e-07 32.0 0.4 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB04570.1 - 7.1e-05 22.6 0.2 7.9e-05 22.5 0.2 1.1 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EGB04570.1 - 0.015 15.5 0.1 0.015 15.5 0.1 1.1 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 PTH2 PF01981.16 EGB04571.1 - 7.4e-16 58.5 0.0 8.5e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 AMP-binding PF00501.28 EGB04572.1 - 5e-69 232.9 0.0 1.6e-68 231.3 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 EGB04572.1 - 1.6e-16 59.3 30.1 4.4e-05 23.0 2.3 5.9 4 1 0 5 5 5 5 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 EGB04572.1 - 2.8e-06 28.2 0.1 2.8e-06 28.2 0.1 4.1 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 EGB04572.1 - 0.00057 19.6 36.7 0.013 15.2 3.9 6.2 2 2 3 5 5 5 3 Hexapeptide repeat of succinyl-transferase PP-binding PF00550.25 EGB04572.1 - 0.0012 19.1 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site PglD_N PF17836.1 EGB04572.1 - 0.036 14.7 0.0 0.082 13.5 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Ephrin_rec_like PF07699.13 EGB04573.1 - 5.4e-05 22.9 19.6 0.00021 21.0 8.1 11.6 6 3 6 13 13 13 7 Putative ephrin-receptor like Lustrin_cystein PF14625.6 EGB04574.1 - 3.1 8.2 24.6 5.3 7.5 1.3 4.7 2 1 2 4 4 4 0 Lustrin, cysteine-rich repeated domain JAMP PF05571.12 EGB04574.1 - 3.5 7.2 5.7 4.2 6.9 5.7 1.1 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Dickkopf_N PF04706.12 EGB04574.1 - 4 8.0 13.2 32 5.1 0.2 3.5 2 1 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region RabGAP-TBC PF00566.18 EGB04575.1 - 6.2e-32 111.0 0.0 8.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Aldolase PF01081.19 EGB04576.1 - 6.3e-31 107.3 0.1 7.4e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase WW PF00397.26 EGB04578.1 - 4.6e-12 45.8 10.2 1e-07 31.9 2.5 3.1 2 1 1 3 3 3 2 WW domain Lycopene_cycl PF05834.12 EGB04579.1 - 0.0002 20.5 2.6 0.16 11.0 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 EGB04579.1 - 0.0063 15.9 5.1 0.019 14.3 5.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGB04579.1 - 0.011 14.6 1.6 0.12 11.2 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EGB04579.1 - 0.018 13.7 0.7 0.061 12.0 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EGB04579.1 - 0.028 13.7 0.2 0.69 9.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EGB04579.1 - 0.034 14.7 0.1 0.095 13.3 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB04579.1 - 0.24 10.6 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Chlam_PMP PF02415.17 EGB04580.1 - 0.084 13.4 25.2 12 6.6 1.4 7.7 7 1 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glug PF07581.12 EGB04580.1 - 2.6 8.6 6.0 59 4.4 1.0 3.9 2 0 0 2 2 2 0 The GLUG motif Sel1 PF08238.12 EGB04581.1 - 5.9e-11 42.7 1.1 5.2e-06 27.0 0.1 2.6 2 0 0 2 2 2 2 Sel1 repeat zf-MYND PF01753.18 EGB04581.1 - 1.8e-09 37.5 11.3 1.8e-09 37.5 11.3 2.5 2 0 0 2 2 2 1 MYND finger Fer2_3 PF13085.6 EGB04581.1 - 0.001 19.1 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-C3HC4_3 PF13920.6 EGB04581.1 - 0.0041 16.9 6.6 0.0041 16.9 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.13 EGB04581.1 - 2.4 5.9 14.2 0.55 8.0 7.0 2.0 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 Glyco_hydro_92 PF07971.12 EGB04582.1 - 7.8e-56 189.9 0.0 1.1e-55 189.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 EF-hand_1 PF00036.32 EGB04582.1 - 0.00076 18.9 0.2 0.0059 16.1 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB04582.1 - 0.00084 19.1 0.2 0.0067 16.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain Sulfotransfer_3 PF13469.6 EGB04582.1 - 0.0025 18.2 0.0 0.0042 17.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family EF-hand_7 PF13499.6 EGB04582.1 - 0.015 15.7 0.0 0.039 14.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Kinesin PF00225.23 EGB04583.1 - 2.2e-77 260.2 0.0 2.5e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB04583.1 - 4.4e-12 46.2 0.0 3.7e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Microtubule binding Thymidylat_synt PF00303.19 EGB04584.1 - 1.5e-114 381.7 0.0 1.8e-114 381.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 EGB04584.1 - 3.1e-33 114.8 0.0 8.1e-33 113.4 0.0 1.6 2 0 0 2 2 2 1 Dihydrofolate reductase Ion_trans_2 PF07885.16 EGB04585.1 - 5.8e-15 55.0 7.2 7.7e-15 54.6 7.2 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB04585.1 - 1e-05 24.9 0.3 1.5e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EGB04585.1 - 0.00047 19.5 0.7 0.043 13.4 0.1 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EGB04585.1 - 0.0035 17.2 0.8 0.12 12.4 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EGB04585.1 - 0.015 15.8 1.4 0.064 13.7 0.4 2.1 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 EGB04585.1 - 0.059 12.9 2.1 0.11 12.0 0.5 2.3 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 EGB04585.1 - 0.14 12.0 1.0 11 5.9 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair malic PF00390.19 EGB04586.1 - 5.4e-69 231.6 0.0 8.2e-69 231.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 EGB04586.1 - 1e-68 231.4 0.0 1.5e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain WD40 PF00400.32 EGB04586.1 - 3.8e-05 24.4 0.9 0.14 13.1 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat EF-hand_6 PF13405.6 EGB04586.1 - 0.0028 17.4 0.0 0.0092 15.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EGB04586.1 - 0.0098 15.4 0.1 0.025 14.1 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGB04586.1 - 0.071 13.6 0.1 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 EGB04586.1 - 0.2 11.5 0.2 0.75 9.7 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair ASH PF15780.5 EGB04587.1 - 3.9e-16 59.1 0.0 0.00023 21.3 0.0 8.2 8 0 0 8 8 8 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGB04587.1 - 5.4e-07 29.7 0.0 0.0039 17.3 0.0 3.5 3 0 0 3 3 3 2 Flagellar-associated PapD-like Ank_2 PF12796.7 EGB04587.1 - 3e-05 24.5 0.0 0.00011 22.7 0.0 1.9 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB04587.1 - 0.0019 18.5 0.6 0.047 14.0 0.3 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB04587.1 - 0.0024 18.2 0.2 0.025 15.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGB04587.1 - 0.0045 17.4 0.2 0.044 14.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGB04587.1 - 0.0048 17.4 0.0 0.18 12.4 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Motile_Sperm PF00635.26 EGB04587.1 - 0.012 15.4 0.0 15 5.5 0.0 4.7 6 0 0 6 6 6 0 MSP (Major sperm protein) domain DUF1573 PF07610.11 EGB04587.1 - 0.054 13.5 0.0 17 5.5 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1573) SpoIIIAH PF12685.7 EGB04587.1 - 0.89 9.3 6.7 2.1 8.1 6.7 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein AP3D1 PF06375.11 EGB04587.1 - 2.1 8.5 8.6 0.35 11.1 3.9 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Vps35 PF03635.17 EGB04588.1 - 5e-118 395.6 0.0 6.4e-118 395.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 SWIM PF04434.17 EGB04588.1 - 0.0038 16.8 1.9 0.0094 15.6 1.9 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_11 PF17123.5 EGB04588.1 - 0.16 11.7 0.3 0.79 9.5 0.2 2.2 2 0 0 2 2 2 0 RING-like zinc finger PRP1_N PF06424.12 EGB04589.1 - 2.3e-51 174.1 0.2 4.3e-51 173.2 0.2 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGB04589.1 - 1.8e-21 75.0 63.9 0.0051 17.5 0.2 15.1 6 4 9 15 15 15 11 Tetratricopeptide repeat TPR_19 PF14559.6 EGB04589.1 - 2e-07 31.4 30.2 3.8e-05 24.1 0.1 9.2 8 2 3 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB04589.1 - 0.0016 18.0 0.5 2 8.2 0.0 5.4 6 1 1 7 7 7 1 TPR repeat TPR_2 PF07719.17 EGB04589.1 - 0.0021 18.0 7.3 0.53 10.5 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat Thioredoxin_3 PF13192.6 EGB04589.1 - 0.14 12.2 0.0 50 4.0 0.0 3.9 4 0 0 4 4 4 0 Thioredoxin domain APG6_N PF17675.1 EGB04589.1 - 0.29 11.7 7.6 0.05 14.1 1.4 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Cyclin_N PF00134.23 EGB04590.1 - 3.8e-46 156.0 1.1 9.9e-44 148.1 0.3 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGB04590.1 - 1e-17 64.3 0.1 1.7e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain PRiA4_ORF3 PF07929.11 EGB04591.1 - 1.2e-22 80.4 0.0 3e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Plasmid pRiA4b ORF-3-like protein DUF305 PF03713.13 EGB04591.1 - 0.042 14.0 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF305) ArabFuran-catal PF09206.11 EGB04592.1 - 5.9e-114 380.6 8.1 9.8e-114 379.9 8.1 1.3 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic EF-hand_1 PF00036.32 EGB04593.1 - 4e-30 101.1 19.3 0.00016 20.9 0.1 8.7 8 0 0 8 8 8 8 EF hand EF-hand_7 PF13499.6 EGB04593.1 - 1e-25 89.9 15.9 4.2e-09 36.7 0.0 5.8 4 1 3 7 7 7 6 EF-hand domain pair EF-hand_6 PF13405.6 EGB04593.1 - 1.5e-25 86.9 17.4 5.6e-05 22.8 0.0 8.7 8 0 0 8 8 8 6 EF-hand domain EF-hand_5 PF13202.6 EGB04593.1 - 6.5e-18 63.3 22.4 0.0039 16.6 0.0 8.3 8 0 0 8 8 8 6 EF hand EF-hand_8 PF13833.6 EGB04593.1 - 8e-10 38.4 7.3 0.0089 15.9 0.1 6.9 7 1 1 8 8 8 3 EF-hand domain pair EF-hand_4 PF12763.7 EGB04593.1 - 0.42 10.6 13.4 11 6.1 0.9 5.1 5 2 1 6 6 6 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB04593.1 - 5.6 7.3 13.0 84 3.5 0.1 5.8 5 1 0 5 5 5 0 Secreted protein acidic and rich in cysteine Ca binding region CRAL_TRIO PF00650.20 EGB04594.1 - 2.1e-20 73.0 0.0 3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain LRR_8 PF13855.6 EGB04595.1 - 7.1e-15 54.5 8.4 4e-06 26.5 0.0 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EGB04595.1 - 6.6e-12 45.4 5.2 6.3e-05 23.3 4.3 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) CheY-binding PF09078.11 EGB04595.1 - 0.37 11.0 1.1 18 5.5 0.0 2.7 2 1 1 3 3 3 0 CheY binding PhoD PF09423.10 EGB04598.1 - 8.4e-06 25.0 0.1 0.0091 15.0 0.0 2.1 1 1 1 2 2 2 2 PhoD-like phosphatase Metallophos PF00149.28 EGB04598.1 - 0.1 13.1 0.0 2.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Guanylate_kin PF00625.21 EGB04599.1 - 2.9e-49 167.2 0.0 3.7e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 EGB04599.1 - 0.00032 20.8 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGB04599.1 - 0.0079 16.4 0.0 0.28 11.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB04599.1 - 0.021 15.4 0.1 0.12 13.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB04599.1 - 0.099 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NFACT-R_2 PF18297.1 EGB04600.1 - 2.3e-06 27.7 2.4 5.7 7.2 0.1 7.0 1 1 6 7 7 7 1 NFACT protein RNA binding domain Clathrin_H_link PF13838.6 EGB04600.1 - 0.0001 22.2 8.5 35 4.4 0.0 7.5 8 0 0 8 8 8 1 Clathrin-H-link Hydrolase_like PF13242.6 EGB04600.1 - 0.0028 17.7 9.9 54 4.0 0.2 7.0 2 2 3 5 5 5 0 HAD-hyrolase-like RXLR PF16810.5 EGB04600.1 - 4.6 7.7 31.2 12 6.3 0.8 7.3 1 1 6 7 7 7 0 RXLR phytopathogen effector protein, Avirulence activity HWE_HK PF07536.14 EGB04600.1 - 6.4 7.6 40.0 19 6.0 0.6 8.3 2 1 7 9 9 9 0 HWE histidine kinase Aldo_ket_red PF00248.21 EGB04601.1 - 7.7e-60 202.6 0.0 8.9e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family U-box PF04564.15 EGB04602.1 - 4.3e-19 68.4 0.0 4.9e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB04602.1 - 1.2e-05 25.1 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EGB04602.1 - 0.0016 18.6 0.0 0.002 18.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGB04602.1 - 0.063 13.3 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 RING-type zinc-finger Ank_5 PF13857.6 EGB04603.1 - 6.6e-22 77.3 1.9 9.6e-09 35.4 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB04603.1 - 1.8e-18 66.0 1.5 0.00011 22.5 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EGB04603.1 - 2.1e-17 63.5 0.0 8.9e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB04603.1 - 2.3e-14 52.1 0.0 0.00089 19.5 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EGB04603.1 - 1.8e-13 50.7 0.4 1.4e-05 25.5 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) MORN PF02493.20 EGB04604.1 - 5.2e-41 136.1 51.4 2.1e-08 33.6 1.3 8.7 9 0 0 9 9 9 8 MORN repeat DsbC PF11412.8 EGB04604.1 - 0.25 11.4 1.2 0.39 10.8 0.2 1.8 1 1 0 2 2 2 0 Disulphide bond corrector protein DsbC AMP-binding PF00501.28 EGB04605.1 - 4.3e-60 203.5 0.0 5.2e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Neur_chan_LBD PF02931.23 EGB04606.1 - 4.3e-10 39.4 0.0 7.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 EGB04606.1 - 3.4e-06 27.3 1.7 4.2e-06 27.0 1.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Cas1_AcylT PF07779.12 EGB04607.1 - 3.3e-56 191.2 0.1 5.4e-56 190.5 0.1 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF3397 PF11877.8 EGB04607.1 - 0.091 13.0 0.4 0.35 11.1 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) RCDG1 PF15725.5 EGB04607.1 - 0.88 10.0 14.3 0.03 14.7 0.7 3.3 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Thioredoxin PF00085.20 EGB04608.1 - 2.9e-25 88.2 0.1 1.5e-17 63.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EGB04608.1 - 1.1e-14 55.0 0.0 2.7e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EGB04608.1 - 1.3e-07 31.2 0.0 1.1e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGB04608.1 - 1.4e-05 25.1 0.0 4.8e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB04608.1 - 0.032 14.7 0.0 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredox_DsbH PF03190.15 EGB04608.1 - 0.036 14.0 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF255 ABC_tran PF00005.27 EGB04609.1 - 6.1e-43 146.6 0.0 7.4e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGB04609.1 - 7.8e-43 147.1 2.4 9.3e-25 87.8 0.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 EGB04609.1 - 5.4e-06 26.1 0.7 0.032 14.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB04609.1 - 1.5e-05 25.2 0.5 0.41 10.9 0.1 3.7 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGB04609.1 - 1.6e-05 24.4 0.0 3.1 7.2 0.0 4.1 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGB04609.1 - 0.00014 21.9 0.1 0.38 10.8 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB04609.1 - 0.00031 21.2 13.6 0.014 15.8 0.7 3.4 3 1 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGB04609.1 - 0.00048 20.1 0.2 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 EGB04609.1 - 0.00064 19.5 0.1 0.047 13.4 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGB04609.1 - 0.0023 18.1 1.2 0.59 10.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 EGB04609.1 - 0.0028 17.8 1.6 0.11 12.6 0.2 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 EGB04609.1 - 0.0039 17.0 0.0 5.4 6.7 0.0 3.4 3 1 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGB04609.1 - 0.0045 17.4 0.0 3 8.3 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EGB04609.1 - 0.015 15.3 0.1 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 EGB04609.1 - 0.016 15.7 0.3 7.8 6.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EGB04609.1 - 0.019 14.5 0.0 2.8 7.4 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain SbcCD_C PF13558.6 EGB04609.1 - 0.021 15.1 2.1 1.9 8.8 0.1 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EGB04609.1 - 0.027 14.0 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 EGB04609.1 - 0.027 13.7 0.2 4.1 6.5 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EGB04609.1 - 0.03 13.9 15.6 0.54 9.8 0.1 4.6 5 0 0 5 5 5 0 AAA domain DEAD PF00270.29 EGB04609.1 - 0.041 13.6 0.0 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.12 EGB04609.1 - 0.046 13.6 0.1 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EGB04609.1 - 0.076 13.6 0.0 14 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EGB04609.1 - 0.09 12.8 0.0 0.44 10.6 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 EGB04609.1 - 0.14 11.9 0.2 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 EGB04609.1 - 0.16 12.4 0.1 14 6.1 0.0 2.7 3 0 0 3 3 2 0 RNA helicase PLDc_2 PF13091.6 EGB04610.1 - 1.1e-14 54.4 0.0 4.9e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGB04610.1 - 0.00057 20.0 2.4 0.054 13.7 0.2 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif AAA_28 PF13521.6 EGB04611.1 - 7.4 6.8 9.2 0.41 10.9 2.3 2.5 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 EGB04613.1 - 4.9e-33 114.6 0.0 7.9e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04613.1 - 2.8e-18 66.1 0.0 1.4e-17 63.9 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 EGB04613.1 - 6.1e-18 65.2 4.9 3.7e-09 37.0 0.8 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB04613.1 - 7.5e-12 45.5 9.6 6.5e-07 29.8 0.3 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB04613.1 - 1.1e-11 44.7 15.9 1.1e-05 25.6 0.9 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB04613.1 - 8.7e-10 38.0 6.3 0.16 12.6 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EGB04613.1 - 9.8e-10 38.4 14.2 0.00087 19.6 0.1 6.4 6 0 0 6 6 6 3 Ankyrin repeat Glyco_tranf_2_4 PF13704.6 EGB04614.1 - 3.5e-09 37.1 0.0 6.2e-08 33.1 0.0 3.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EGB04614.1 - 9e-05 22.3 0.0 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 92 DUF1336 PF07059.12 EGB04615.1 - 6e-40 137.7 0.0 1.1e-39 136.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) MFS_1 PF07690.16 EGB04615.1 - 2.1e-19 69.7 27.9 2.1e-19 69.7 27.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB04615.1 - 0.00031 19.7 1.3 0.00052 19.0 1.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGB04615.1 - 0.26 10.1 0.8 2.7 6.8 0.8 2.1 1 1 0 1 1 1 0 MFS_1 like family Syja_N PF02383.18 EGB04617.1 - 9.6e-15 54.7 0.0 6.6e-12 45.4 0.0 2.0 2 0 0 2 2 2 2 SacI homology domain TetR_C_15 PF17918.1 EGB04618.1 - 0.26 12.1 5.2 0.63 10.8 4.7 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2849 PF11011.8 EGB04618.1 - 7.6 7.3 11.3 0.81 10.4 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) AA_kinase PF00696.28 EGB04619.1 - 2.5e-20 73.1 0.1 3.5e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family DUF3197 PF11432.8 EGB04619.1 - 0.057 13.3 0.9 0.97 9.3 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3197) WSC PF01822.19 EGB04620.1 - 5.5e-12 45.7 10.2 1.1e-11 44.8 10.2 1.4 1 0 0 1 1 1 1 WSC domain BNR PF02012.20 EGB04620.1 - 0.0016 18.1 6.7 0.77 10.0 0.2 4.0 3 0 0 3 3 3 2 BNR/Asp-box repeat GNT-I PF03071.15 EGB04621.1 - 2.2e-37 128.8 0.4 2.5e-37 128.7 0.4 1.0 1 0 0 1 1 1 1 GNT-I family ADH_zinc_N_2 PF13602.6 EGB04622.1 - 2.3e-16 61.0 0.3 4.9e-16 60.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGB04622.1 - 3.2e-14 53.0 4.9 7.7e-14 51.8 4.9 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 EGB04622.1 - 0.0088 15.8 0.9 0.017 14.8 0.9 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LDcluster4 PF18306.1 EGB04622.1 - 0.0099 15.5 1.8 0.021 14.4 1.8 1.4 1 0 0 1 1 1 1 SLOG cluster4 family DUF2855 PF11017.8 EGB04622.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) adh_short PF00106.25 EGB04622.1 - 0.02 14.4 2.4 0.044 13.2 2.4 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 EGB04622.1 - 0.021 14.3 0.3 0.03 13.8 0.3 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EGB04622.1 - 0.07 13.3 0.5 0.23 11.6 0.4 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 EGB04622.1 - 0.07 12.4 0.2 0.61 9.4 0.1 2.3 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ACP_syn_III_C PF08541.10 EGB04622.1 - 0.13 12.4 0.8 0.54 10.5 0.2 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CbiX PF01903.17 EGB04623.1 - 1.9e-22 79.6 0.0 2.5e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 EGB04623.1 - 0.029 13.7 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Ferrochelatase PF00762.19 EGB04623.1 - 0.074 12.1 0.0 0.083 12.0 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase Ion_trans_2 PF07885.16 EGB04624.1 - 7.1e-26 90.0 16.1 2e-14 53.3 1.2 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 EGB04624.1 - 5.7e-10 38.8 3.8 5.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 EGB04624.1 - 2.4e-05 24.7 0.8 0.0011 19.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB04624.1 - 9.8e-05 21.6 6.3 0.0039 16.6 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB04624.1 - 0.0025 17.6 4.4 0.0073 16.2 0.6 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EGB04624.1 - 0.015 14.7 8.2 0.042 13.4 0.7 2.6 2 0 0 2 2 2 0 EF hand DUF4602 PF15375.6 EGB04624.1 - 0.6 10.4 9.5 1.1 9.6 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) EF-hand_8 PF13833.6 EGB04624.1 - 3.6 7.5 6.0 14 5.6 0.5 2.8 2 0 0 2 2 2 0 EF-hand domain pair GST_C_2 PF13410.6 EGB04625.1 - 1.6e-08 34.4 0.1 3.5e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB04625.1 - 0.0079 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGB04625.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB04625.1 - 0.032 14.4 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB04625.1 - 0.094 13.1 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGB04625.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain E1_dh PF00676.20 EGB04626.1 - 4.8e-84 281.9 0.1 5.4e-84 281.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGB04626.1 - 2.8e-05 23.9 3.6 7.2e-05 22.6 0.4 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EGB04626.1 - 0.00018 20.9 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 EGB04626.1 - 0.0019 17.2 0.0 0.004 16.1 0.0 1.5 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DUF2849 PF11011.8 EGB04626.1 - 1.2 9.9 6.1 0.64 10.7 1.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) SnoaL_2 PF12680.7 EGB04626.1 - 2.2 9.0 8.6 1.2 9.8 3.4 2.7 2 1 2 4 4 4 0 SnoaL-like domain Peptidase_S24 PF00717.23 EGB04627.1 - 2.1e-13 50.0 0.0 3.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGB04627.1 - 5.6e-13 48.9 0.0 8.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Kinesin PF00225.23 EGB04628.1 - 1.3e-15 57.1 0.0 1.4e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C1 PF00112.23 EGB04630.1 - 5.7e-55 186.8 6.5 7e-55 186.5 6.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB04630.1 - 0.00069 18.5 1.2 0.02 13.7 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family zf-C3HC4_3 PF13920.6 EGB04631.1 - 5.7 6.9 11.5 1.9 8.4 6.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Arf PF00025.21 EGB04632.1 - 2.3e-64 216.0 0.1 2.6e-64 215.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGB04632.1 - 5.8e-12 45.4 0.0 5.2e-06 25.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGB04632.1 - 6.3e-12 45.8 0.0 9.6e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGB04632.1 - 4.9e-10 39.2 0.0 5.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGB04632.1 - 5.9e-09 35.6 0.0 8.2e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGB04632.1 - 1.4e-08 34.4 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB04632.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB04632.1 - 0.012 15.5 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EGB04632.1 - 0.018 14.6 0.0 0.2 11.1 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 EGB04632.1 - 0.028 14.5 0.0 0.063 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB04632.1 - 0.042 14.2 0.0 2.9 8.3 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGB04632.1 - 0.047 14.3 0.0 0.094 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGB04632.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Fcf2 PF08698.11 EGB04633.1 - 2.4e-22 79.1 0.0 2.7e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Sua5_yciO_yrdC PF01300.18 EGB04634.1 - 5.2e-43 146.6 0.0 7.9e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGB04634.1 - 1.6e-11 44.9 0.4 2.6e-11 44.2 0.4 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding AAA_16 PF13191.6 EGB04635.1 - 0.0034 17.8 7.9 0.057 13.8 7.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGB04635.1 - 0.041 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Rhodanese PF00581.20 EGB04635.1 - 0.044 14.3 0.2 0.35 11.4 0.1 2.5 3 0 0 3 3 3 0 Rhodanese-like domain AAA_22 PF13401.6 EGB04635.1 - 0.19 12.0 0.8 3.1 8.1 0.8 2.5 1 1 1 2 2 2 0 AAA domain DSPc PF00782.20 EGB04635.1 - 0.2 11.5 0.1 0.33 10.7 0.1 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain U-box PF04564.15 EGB04636.1 - 0.00056 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain Hist_deacetyl PF00850.19 EGB04637.1 - 1e-81 274.8 0.0 1.2e-81 274.6 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain RRM_1 PF00076.22 EGB04638.1 - 4e-15 55.4 0.0 8.3e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 EGB04638.1 - 0.0086 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Sporulation protein family 7 RRM_5 PF13893.6 EGB04638.1 - 0.045 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGB04638.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EGF_2 PF07974.13 EGB04639.1 - 1.8e-06 28.2 52.5 0.0064 16.8 10.3 5.0 4 1 0 4 4 4 3 EGF-like domain EGF_2 PF07974.13 EGB04640.1 - 3.9e-10 39.9 36.8 0.00066 20.0 6.4 4.4 4 0 0 4 4 4 4 EGF-like domain EGF PF00008.27 EGB04640.1 - 0.0076 16.5 2.6 0.0076 16.5 2.6 4.7 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 EGB04640.1 - 0.019 15.6 2.2 0.019 15.6 2.2 4.9 5 1 0 5 5 5 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGB04640.1 - 0.024 14.8 29.1 2.1 8.6 12.4 3.7 2 1 1 3 3 3 0 Laminin EGF domain Peptidase_C1 PF00112.23 EGB04641.1 - 4.8e-45 154.3 6.2 5.7e-45 154.1 6.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB04641.1 - 0.0038 16.1 0.8 0.0053 15.6 0.8 1.1 1 0 0 1 1 1 1 Peptidase C1-like family PrmA PF06325.13 EGB04642.1 - 2.2e-10 40.4 3.3 2.3e-06 27.2 1.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB04642.1 - 4.1e-08 32.9 2.0 3.2e-07 30.0 0.6 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB04642.1 - 5.6e-08 33.4 1.5 1.7e-05 25.4 0.4 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB04642.1 - 3e-06 27.1 0.1 8e-06 25.7 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB04642.1 - 0.00015 22.5 0.3 0.001 19.8 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGB04642.1 - 0.00018 21.3 0.0 0.061 13.0 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_11 PF08241.12 EGB04642.1 - 0.00032 21.3 0.6 0.077 13.7 0.1 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGB04642.1 - 0.00064 19.7 0.2 0.0019 18.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB04642.1 - 0.00089 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF212 PF02681.14 EGB04642.1 - 0.0072 16.4 0.0 0.12 12.5 0.0 2.3 1 1 0 2 2 2 1 Divergent PAP2 family RrnaAD PF00398.20 EGB04642.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PAP2 PF01569.21 EGB04642.1 - 0.015 15.1 9.4 0.092 12.5 7.6 2.5 1 1 1 2 2 2 0 PAP2 superfamily PCMT PF01135.19 EGB04642.1 - 0.017 14.8 0.6 0.037 13.8 0.2 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EGB04642.1 - 0.2 11.4 2.0 0.2 11.4 0.3 1.7 2 0 0 2 2 2 0 Met-10+ like-protein DUF5464 PF17552.2 EGB04642.1 - 2.9 8.2 9.6 23 5.3 2.6 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5464) KH_6 PF15985.5 EGB04643.1 - 3.6e-12 46.4 0.0 5.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 KH domain DnaJ_C PF01556.18 EGB04644.1 - 1.5e-33 115.9 0.0 2.1e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB04644.1 - 2e-27 95.1 1.1 3.2e-27 94.4 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain LprI PF07007.12 EGB04644.1 - 0.064 13.9 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Lysozyme inhibitor LprI DUF3106 PF11304.8 EGB04644.1 - 0.44 11.0 1.6 2.5 8.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) cNMP_binding PF00027.29 EGB04645.1 - 1e-10 41.5 0.0 7.8e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB04645.1 - 6.7e-07 28.8 4.3 1e-06 28.2 4.3 1.2 1 0 0 1 1 1 1 Ion transport protein Glyco_hydro_67M PF07488.12 EGB04646.1 - 7.7e-86 288.1 0.0 1e-85 287.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 EGB04646.1 - 5.8e-39 133.9 0.0 7e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 67 C-terminus Glyco_transf_92 PF01697.27 EGB04647.1 - 3.7e-06 26.8 0.0 5.2e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EGB04647.1 - 0.0026 18.2 1.4 0.0094 16.5 1.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Metallophos PF00149.28 EGB04648.1 - 0.0052 17.3 0.0 0.0071 16.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IF4E PF01652.18 EGB04649.1 - 1.5e-31 109.4 2.9 1.6e-31 109.2 2.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RRM_1 PF00076.22 EGB04650.1 - 7.5e-73 240.3 0.1 4.2e-19 68.1 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGB04650.1 - 7.3e-07 28.8 0.0 0.14 11.8 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGB04650.1 - 1.3e-06 28.3 0.1 0.53 10.3 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGB04650.1 - 3.2e-05 24.0 0.0 1.7 8.9 0.0 4.5 4 1 0 4 4 4 2 RNA recognition motif Limkain-b1 PF11608.8 EGB04650.1 - 0.0015 18.6 0.0 1.2 9.3 0.0 4.0 4 0 0 4 4 4 1 Limkain b1 SET_assoc PF11767.8 EGB04650.1 - 0.05 13.2 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RNA_bind PF08675.11 EGB04650.1 - 0.05 13.6 0.6 1.4 9.0 0.0 3.1 4 0 0 4 4 4 0 RNA binding domain LUD_dom PF02589.15 EGB04650.1 - 0.16 11.7 0.5 0.39 10.4 0.1 1.8 2 0 0 2 2 2 0 LUD domain Vps51 PF08700.11 EGB04651.1 - 0.025 14.6 2.6 0.025 14.6 2.6 3.1 3 1 0 3 3 3 0 Vps51/Vps67 GCR PF02155.15 EGB04651.1 - 0.03 13.4 0.4 0.04 13.0 0.4 1.3 1 0 0 1 1 1 0 Glucocorticoid receptor DUF3209 PF11483.8 EGB04651.1 - 0.033 14.7 7.0 2 8.9 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) YtxH PF12732.7 EGB04651.1 - 0.086 13.4 3.7 1.4 9.5 1.2 3.1 2 1 0 2 2 2 0 YtxH-like protein PCB_OB PF17092.5 EGB04651.1 - 0.65 10.8 3.3 1.1 10.1 0.1 2.4 2 1 0 2 2 2 0 Penicillin-binding protein OB-like domain Arm PF00514.23 EGB04652.1 - 1.3e-19 69.5 45.3 0.0033 17.4 0.0 13.7 15 0 0 15 15 15 8 Armadillo/beta-catenin-like repeat DUF383 PF04063.14 EGB04652.1 - 0.0064 16.2 4.6 0.11 12.1 0.0 3.9 3 2 2 5 5 5 1 Domain of unknown function (DUF383) KAP PF05804.12 EGB04652.1 - 0.2 9.8 11.8 3.1 5.8 0.2 4.3 4 1 1 5 5 5 0 Kinesin-associated protein (KAP) RPAP1_C PF08620.10 EGB04652.1 - 5.5 7.2 6.0 4.3 7.5 0.1 3.2 3 0 0 3 3 3 0 RPAP1-like, C-terminal Pkinase PF00069.25 EGB04653.1 - 6.4e-63 212.6 0.0 7.7e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04653.1 - 6.3e-28 97.8 0.5 1.5e-27 96.5 0.5 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB04653.1 - 2.8e-06 26.4 0.0 4.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGB04653.1 - 0.00035 19.6 0.3 0.00065 18.8 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB04653.1 - 0.0077 16.2 0.1 0.17 11.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGB04653.1 - 0.015 14.9 0.1 0.22 11.1 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGB04653.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like EF-hand_1 PF00036.32 EGB04654.1 - 5.4e-18 63.1 6.3 2.8e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB04654.1 - 3.7e-17 60.7 6.4 0.00024 20.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGB04654.1 - 8.5e-17 61.4 7.6 1.2e-11 44.9 1.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB04654.1 - 3.7e-10 39.5 9.4 9.8e-07 28.5 0.9 4.0 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB04654.1 - 2.6e-09 36.2 2.4 0.01 15.3 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 EGB04654.1 - 3.8e-08 33.2 3.1 0.00054 19.9 0.1 3.2 2 1 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB04654.1 - 3.9e-06 27.2 1.2 3.2e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGB04654.1 - 8.2e-05 22.9 0.2 0.63 10.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain DUF713 PF05218.14 EGB04654.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) EGF_2 PF07974.13 EGB04655.1 - 8.9e-19 67.6 120.4 5.3e-06 26.7 8.1 10.9 11 1 0 11 11 11 8 EGF-like domain EGF PF00008.27 EGB04655.1 - 0.00021 21.5 12.8 0.0021 18.3 3.6 10.0 10 0 0 10 10 10 4 EGF-like domain RRM_1 PF00076.22 EGB04655.1 - 0.014 15.2 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APG6 PF04111.12 EGB04656.1 - 1.6e-23 83.6 0.2 2.8e-23 82.8 0.1 1.4 2 0 0 2 2 2 1 Apg6 BARA domain Arm PF00514.23 EGB04657.1 - 3.5e-25 87.2 16.1 1e-09 38.1 0.0 8.4 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGB04657.1 - 9.3e-18 62.8 8.5 1.9e-05 24.5 0.0 7.8 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 EGB04657.1 - 2.8e-14 53.3 11.4 6.6e-05 23.2 0.1 4.5 3 2 1 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 EGB04657.1 - 1.4e-11 44.6 17.6 0.00087 19.7 0.2 6.7 5 1 2 7 7 7 6 HEAT-like repeat Cnd1 PF12717.7 EGB04657.1 - 1.2e-10 41.7 2.5 0.0017 18.4 0.2 4.5 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGB04657.1 - 3.5e-09 35.8 0.5 0.0022 16.6 0.0 3.7 2 2 1 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.11 EGB04657.1 - 8.9e-09 35.4 0.1 0.039 13.7 0.0 3.8 2 1 0 3 3 3 2 DNA alkylation repair enzyme CLASP_N PF12348.8 EGB04657.1 - 2e-06 27.6 0.1 0.086 12.4 0.0 3.4 3 1 0 3 3 3 2 CLASP N terminal Atx10homo_assoc PF09759.9 EGB04657.1 - 6.8e-06 26.0 0.7 0.085 12.9 0.1 4.0 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain CHASE6_C PF17150.4 EGB04657.1 - 1e-05 26.1 0.9 14 6.5 0.0 6.0 5 1 0 5 5 5 0 C-terminal domain of two-partite extracellular sensor domain Proteasom_PSMB PF10508.9 EGB04657.1 - 8e-05 21.3 6.7 0.0013 17.4 0.2 3.5 2 1 2 4 4 4 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 EGB04657.1 - 0.0023 18.0 0.7 21 5.3 0.0 4.0 3 1 2 5 5 5 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 EGB04657.1 - 0.01 16.4 0.2 0.5 11.0 0.1 3.0 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_UF PF18817.1 EGB04657.1 - 0.012 15.9 1.1 1.9 8.8 0.0 4.2 6 0 0 6 6 4 0 Repeat of uncharacterized protein PH0542 RTP1_C1 PF10363.9 EGB04657.1 - 0.3 11.3 1.4 1.6 8.9 0.0 2.8 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3361 PF11841.8 EGB04657.1 - 0.38 10.7 2.0 25 4.8 0.1 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 EGB04657.1 - 1.5 9.7 17.7 21 6.2 0.1 6.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Motile_Sperm PF00635.26 EGB04658.1 - 1.1e-15 57.4 1.1 1.1e-14 54.2 0.5 2.6 1 1 2 3 3 3 1 MSP (Major sperm protein) domain Cep57_CLD_2 PF14197.6 EGB04658.1 - 0.065 13.3 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Spc24 PF08286.11 EGB04658.1 - 0.086 13.1 0.2 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Golgin_A5 PF09787.9 EGB04659.1 - 0.2 11.1 9.8 0.26 10.7 9.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 EGB04659.1 - 0.25 11.4 6.5 0.35 11.0 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Kinesin PF00225.23 EGB04660.1 - 4.5e-96 321.7 0.0 5.4e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB04660.1 - 2.4e-41 141.1 0.0 3.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding RIIa PF02197.17 EGB04660.1 - 0.032 13.9 0.1 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Hydrolase_4 PF12146.8 EGB04661.1 - 6.7e-11 41.9 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGB04661.1 - 1.9e-06 27.7 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGB04661.1 - 4.3e-05 23.3 0.0 7.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB04661.1 - 4.4e-05 24.2 3.0 4.4e-05 24.2 3.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 EGB04661.1 - 0.019 14.5 0.1 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 2) SHIPPO-rpt PF07004.12 EGB04662.1 - 4.6e-07 30.4 31.7 0.07 14.1 0.1 5.5 6 0 0 6 6 6 4 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EGB04662.1 - 0.013 15.3 1.0 3.1 7.7 0.1 3.4 4 0 0 4 4 4 0 Exosome complex exonuclease RRP4 N-terminal region WD40 PF00400.32 EGB04663.1 - 2e-05 25.2 0.4 0.013 16.3 0.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 EGB04663.1 - 4.6e-05 22.3 0.0 8.4e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Kdo PF06293.14 EGB04663.1 - 0.0091 15.4 0.9 0.014 14.7 0.3 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TMIE PF16038.5 EGB04663.1 - 0.15 12.0 0.3 0.42 10.5 0.1 1.8 2 0 0 2 2 2 0 TMIE protein DUF3543 PF12063.8 EGB04663.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Tctex-1 PF03645.13 EGB04664.1 - 3.6e-28 97.8 1.4 4.3e-28 97.6 1.4 1.1 1 0 0 1 1 1 1 Tctex-1 family Pkinase PF00069.25 EGB04665.1 - 2e-63 214.2 0.0 2.5e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04665.1 - 2.4e-30 105.7 0.0 3.1e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04665.1 - 1e-05 25.0 0.0 0.00012 21.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGB04665.1 - 0.00025 20.1 0.1 0.041 12.8 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain DUF1619 PF07773.11 EGB04666.1 - 7.3e-30 105.0 0.7 2.9e-29 103.0 0.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1619) TH1 PF04858.13 EGB04667.1 - 2.9e-18 65.8 0.0 9.1e-18 64.2 0.0 1.6 1 1 0 1 1 1 1 TH1 protein EGF_2 PF07974.13 EGB04668.1 - 0.00088 19.6 13.4 0.0014 18.9 8.6 2.6 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.24 EGB04668.1 - 0.0087 16.2 14.6 0.014 15.5 4.6 2.9 3 0 0 3 3 3 2 Laminin EGF domain Fil_haemagg PF05594.14 EGB04668.1 - 0.21 12.2 17.9 1.1 9.9 5.2 3.3 3 0 0 3 3 3 0 Haemagluttinin repeat Not3 PF04065.15 EGB04669.1 - 1.2e-85 286.6 25.2 1.2e-85 286.6 25.2 2.3 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGB04669.1 - 5.4e-47 159.2 9.5 1.9e-46 157.4 9.5 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF3489 PF11994.8 EGB04671.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) FYDLN_acid PF09538.10 EGB04671.1 - 0.9 10.3 4.2 69 4.2 4.2 2.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) LRR_8 PF13855.6 EGB04672.1 - 5.2e-16 58.1 11.4 4.3e-07 29.6 0.1 5.6 5 1 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 EGB04672.1 - 5.6e-13 47.8 30.3 0.05 13.7 0.2 9.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 EGB04672.1 - 7.8e-13 48.4 13.4 0.00074 19.9 0.1 6.4 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB04672.1 - 0.0086 16.5 9.9 1e+02 4.1 0.1 7.9 9 0 0 9 9 9 0 Leucine Rich Repeat Tctex-1 PF03645.13 EGB04673.1 - 2.2e-26 92.1 0.1 2.6e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family EF-hand_5 PF13202.6 EGB04675.1 - 6.3e-05 22.3 0.0 0.016 14.7 0.0 2.8 2 0 0 2 2 2 2 EF hand PH PF00169.29 EGB04675.1 - 0.0012 19.4 0.1 0.8 10.2 0.0 3.3 2 1 0 2 2 2 1 PH domain EF-hand_6 PF13405.6 EGB04675.1 - 0.0082 16.0 0.0 0.31 11.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGB04675.1 - 0.009 15.5 0.0 0.38 10.4 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGB04675.1 - 0.024 14.5 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 EGB04675.1 - 0.086 13.3 0.0 8.1 7.0 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair Tup_N PF08581.10 EGB04676.1 - 3.4 8.0 20.9 4.3 7.7 0.6 4.7 4 0 0 4 4 4 0 Tup N-terminal EMP70 PF02990.16 EGB04677.1 - 0.018 13.7 1.7 0.018 13.7 1.7 1.8 1 1 1 2 2 2 0 Endomembrane protein 70 cNMP_binding PF00027.29 EGB04679.1 - 1.4e-16 60.3 0.0 2.2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain polyprenyl_synt PF00348.17 EGB04680.1 - 3e-64 216.5 0.2 4e-64 216.1 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase AAA PF00004.29 EGB04681.1 - 2.9e-34 118.3 0.0 4.2e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB04681.1 - 0.00023 21.6 0.1 0.001 19.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGB04681.1 - 0.0022 18.3 0.0 0.061 13.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB04681.1 - 0.0026 17.9 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EGB04681.1 - 0.0033 17.2 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGB04681.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EGB04681.1 - 0.024 14.6 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGB04681.1 - 0.028 13.8 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGB04681.1 - 0.043 13.7 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 EGB04681.1 - 0.06 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB04681.1 - 0.066 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 EGB04681.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EGB04681.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 EGB04681.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Ras PF00071.22 EGB04682.1 - 1.6e-60 203.4 0.0 1.8e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB04682.1 - 2.8e-34 117.9 0.0 4.9e-34 117.1 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB04682.1 - 1.5e-15 57.1 0.0 1.8e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB04682.1 - 0.00011 22.2 0.0 0.00023 21.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGB04682.1 - 0.0037 16.7 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AIG1 PF04548.16 EGB04682.1 - 0.004 16.5 0.4 1 8.6 0.2 2.0 1 1 1 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EGB04682.1 - 0.0043 17.0 0.0 0.94 9.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGB04682.1 - 0.0063 16.1 0.0 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATPase PF06745.13 EGB04682.1 - 0.11 11.8 0.0 7.4 5.8 0.0 2.1 2 0 0 2 2 2 0 KaiC GUN4 PF05419.12 EGB04683.1 - 3.8e-46 156.6 0.1 4.8e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 GUN4-like Clathrin PF00637.20 EGB04684.1 - 0.038 13.9 4.7 0.1 12.5 0.4 2.5 2 1 1 3 3 3 0 Region in Clathrin and VPS Prp19 PF08606.11 EGB04685.1 - 2.5e-32 110.7 0.7 4e-32 110.0 0.7 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.8 EGB04685.1 - 1.9e-06 27.6 0.3 4.4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EGB04685.1 - 7.2e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain WD40 PF00400.32 EGB04685.1 - 1.3 10.0 0.0 1.3 10.0 0.0 3.5 3 1 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.25 EGB04686.1 - 1.4e-53 182.0 0.0 1.9e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04686.1 - 5.6e-33 114.3 0.0 7.5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Prp19 PF08606.11 EGB04687.1 - 6.2e-28 96.6 3.2 1.1e-27 95.8 3.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EGB04687.1 - 9.4e-14 51.6 8.8 2.6e-08 34.4 0.1 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04687.1 - 1.1e-07 32.1 0.0 0.011 16.0 0.0 3.9 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB04687.1 - 2.2 7.1 4.2 2.1 7.2 0.0 2.9 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 EGB04689.1 - 2e-35 122.4 0.0 2.2e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04689.1 - 3.3e-18 65.9 0.0 3.6e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB04689.1 - 1.6e-05 24.3 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB04689.1 - 9.7e-05 21.8 0.0 9.7e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB04689.1 - 0.00016 21.7 0.1 0.00017 21.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB04689.1 - 0.0029 16.4 0.0 0.0034 16.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGB04689.1 - 0.034 13.7 0.0 0.067 12.8 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 EGB04689.1 - 0.22 10.4 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PIG-L PF02585.17 EGB04690.1 - 1e-13 52.1 0.0 1.6e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF5363 PF17320.2 EGB04690.1 - 0.22 11.4 0.1 0.22 11.4 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5363) ThiF PF00899.21 EGB04691.1 - 2.2e-43 148.4 0.1 2.5e-43 148.2 0.1 1.0 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.27 EGB04691.1 - 0.045 14.3 0.1 0.19 12.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGB04691.1 - 0.11 12.6 0.1 0.19 11.8 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lebercilin PF15619.6 EGB04692.1 - 0.042 13.5 7.2 0.079 12.6 7.2 1.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF5372 PF17342.2 EGB04692.1 - 0.087 13.2 0.0 22 5.5 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5372) Rootletin PF15035.6 EGB04692.1 - 1 9.4 7.3 7.7 6.5 5.3 2.0 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3584 PF12128.8 EGB04692.1 - 4.3 4.7 15.5 5.7 4.3 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) VPS9 PF02204.18 EGB04693.1 - 0.00035 20.7 0.0 0.00059 20.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DEAD PF00270.29 EGB04694.1 - 1.1e-45 155.5 0.0 1.8e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB04694.1 - 9.9e-20 70.9 0.0 4e-19 69.0 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB04694.1 - 0.007 16.4 0.0 0.016 15.2 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit COMM_domain PF07258.14 EGB04695.1 - 4.4e-11 42.8 0.0 8.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 COMM domain UBA_e1_thiolCys PF10585.9 EGB04696.1 - 3.6e-14 53.3 0.0 6e-14 52.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site PAN_1 PF00024.26 EGB04696.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 EGB04696.1 - 0.16 11.9 1.8 0.44 10.5 1.8 1.7 1 0 0 1 1 1 0 PAN domain F-actin_cap_A PF01267.17 EGB04700.1 - 7.9e-60 202.5 0.0 9e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Phage_lysis PF03245.13 EGB04700.1 - 5.6 7.1 6.6 0.34 11.1 0.3 1.9 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Pkinase PF00069.25 EGB04701.1 - 0.033 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04701.1 - 0.061 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Methyltransf_11 PF08241.12 EGB04702.1 - 2.7e-09 37.6 0.0 5.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB04702.1 - 3.5e-05 24.5 0.0 5.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB04702.1 - 4.6e-05 24.0 0.0 8.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB04702.1 - 0.00016 21.6 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB04702.1 - 0.0042 16.9 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGB04702.1 - 0.097 13.7 0.0 0.25 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGB04702.1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 2OG-FeII_Oxy_5 PF13759.6 EGB04703.1 - 3.3e-07 30.7 0.0 6.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Tyrosinase PF00264.20 EGB04705.1 - 8.9e-10 39.2 1.5 1.6e-08 35.1 1.5 2.3 1 1 0 1 1 1 1 Common central domain of tyrosinase Frataxin_Cyay PF01491.16 EGB04706.1 - 3.8e-29 100.9 0.0 4.9e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain DnaJ PF00226.31 EGB04707.1 - 9.3e-17 60.9 0.1 1.5e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3391 PF11871.8 EGB04707.1 - 0.0035 17.9 0.1 0.0042 17.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) ADK PF00406.22 EGB04708.1 - 5.2e-44 150.0 0.0 6.4e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGB04708.1 - 1.5e-30 106.4 0.0 2.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB04708.1 - 5.3e-07 29.9 0.0 7.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB04708.1 - 1.2e-06 29.1 0.0 1.7e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGB04708.1 - 0.0078 15.9 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 EGB04708.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Ribosomal_S19 PF00203.21 EGB04709.1 - 3.7e-33 113.2 0.2 5.2e-33 112.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 COPIIcoated_ERV PF07970.12 EGB04710.1 - 8.5e-29 101.0 0.9 1.2e-28 100.5 0.9 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 EGB04710.1 - 4.7e-20 71.5 0.4 1.8e-19 69.6 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB04710.1 - 0.0004 20.8 0.2 0.00096 19.6 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGB04710.1 - 0.00091 18.7 0.3 0.0014 18.0 0.3 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Proteasome PF00227.26 EGB04711.1 - 1.9e-18 66.6 0.1 3.1e-18 66.0 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit DAP_epimerase PF01678.19 EGB04711.1 - 0.066 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase polyprenyl_synt PF00348.17 EGB04712.1 - 6e-66 222.1 0.1 7.1e-66 221.9 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Bromodomain PF00439.25 EGB04713.1 - 2.4e-23 82.0 0.0 2.7e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Bromodomain HAT_KAT11 PF08214.11 EGB04714.1 - 4.4e-28 98.6 1.4 1.6e-26 93.4 0.2 2.2 1 1 1 2 2 2 2 Histone acetylation protein zf-TAZ PF02135.16 EGB04714.1 - 1.4e-12 47.8 15.0 1.4e-12 47.8 15.0 2.5 2 0 0 2 2 2 1 TAZ zinc finger ZZ PF00569.17 EGB04714.1 - 0.015 15.1 5.9 0.061 13.2 5.9 2.0 1 0 0 1 1 1 0 Zinc finger, ZZ type DM PF00751.18 EGB04714.1 - 6.5 6.7 20.1 1.1 9.3 4.9 3.2 3 0 0 3 3 3 0 DM DNA binding domain AAA PF00004.29 EGB04715.1 - 2.9e-39 134.5 0.3 6.7e-39 133.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGB04715.1 - 1.7e-15 56.7 0.2 4e-15 55.5 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGB04715.1 - 2.7e-10 39.9 0.7 8.3e-10 38.3 0.7 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGB04715.1 - 1.5e-06 28.4 0.1 6.5e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGB04715.1 - 2.3e-06 27.6 0.5 1.1e-05 25.4 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB04715.1 - 7.3e-06 26.5 0.1 8.6e-05 23.0 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGB04715.1 - 2.2e-05 24.7 0.2 0.0023 18.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB04715.1 - 0.00055 20.1 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGB04715.1 - 0.0011 18.8 0.1 0.0038 17.0 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EGB04715.1 - 0.0032 17.3 0.3 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB04715.1 - 0.011 16.3 0.4 0.14 12.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 EGB04715.1 - 0.012 14.8 0.9 0.056 12.7 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain CPT PF07931.12 EGB04715.1 - 0.012 15.4 0.0 0.036 13.9 0.0 1.7 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 EGB04715.1 - 0.023 14.1 0.1 0.055 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGB04715.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EGB04715.1 - 0.028 13.9 0.0 0.075 12.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EGB04715.1 - 0.033 14.2 0.2 0.15 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGB04715.1 - 0.033 13.9 0.7 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGB04715.1 - 0.065 12.9 0.0 0.21 11.3 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 EGB04715.1 - 0.078 12.8 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EGB04715.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGB04715.1 - 0.79 9.0 3.6 1.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 EGB04715.1 - 1.1 9.8 3.4 5.4 7.5 0.0 2.7 2 1 1 3 3 3 0 ABC transporter APS_kinase PF01583.20 EGB04717.1 - 2.3e-60 203.1 0.0 3.6e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 EGB04717.1 - 1.5e-51 174.9 0.0 2.3e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 EGB04717.1 - 5.6e-38 130.3 0.0 1e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 EGB04717.1 - 3.6e-27 95.0 0.0 7.7e-26 90.7 0.0 2.6 2 0 0 2 2 2 1 PUA-like domain AAA_33 PF13671.6 EGB04717.1 - 1.8e-05 24.9 0.0 4.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB04717.1 - 0.005 17.4 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB04717.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 EGB04717.1 - 0.052 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.27 EGB04717.1 - 0.055 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EGB04717.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EGB04717.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_transf_8C PF08437.10 EGB04717.1 - 0.08 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal DUF1729 PF08354.10 EGB04717.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) CbiA PF01656.23 EGB04717.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 EGB04717.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 WD40 PF00400.32 EGB04718.1 - 3.3e-68 223.9 23.3 1.1e-09 38.7 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04718.1 - 9.7e-22 77.1 0.9 0.0011 19.2 0.0 7.2 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGB04718.1 - 3.4e-11 43.0 1.1 0.0001 21.8 0.6 4.9 4 2 0 4 4 4 3 WD40-like domain Nup160 PF11715.8 EGB04718.1 - 2.5e-09 36.3 6.8 0.14 10.7 0.1 5.0 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGB04718.1 - 4.8e-07 29.1 6.6 0.062 12.3 0.0 4.9 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB04718.1 - 2.3e-06 27.7 2.9 0.03 14.2 0.3 3.4 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A DUF5570 PF17731.1 EGB04718.1 - 0.0036 17.4 8.9 1.2 9.3 0.1 4.5 1 1 4 5 5 5 1 Family of unknown function (DUF5570) WD40_3 PF15911.5 EGB04718.1 - 0.015 15.3 0.1 4.9 7.2 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat PKD PF00801.20 EGB04718.1 - 0.18 11.7 1.4 27 4.7 0.1 3.3 3 0 0 3 3 3 0 PKD domain CEP19 PF14933.6 EGB04718.1 - 0.21 11.9 0.1 0.31 11.4 0.1 1.2 1 0 0 1 1 1 0 CEP19-like protein DZR PF12773.7 EGB04719.1 - 0.54 10.3 14.1 0.13 12.3 0.6 3.3 3 0 0 3 3 3 0 Double zinc ribbon C1_1 PF00130.22 EGB04719.1 - 5.3 7.0 12.1 2.1 8.3 1.3 3.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) COP-gamma_platf PF08752.10 EGB04720.1 - 2.1e-10 40.9 0.0 9.6e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Vps39_2 PF10367.9 EGB04720.1 - 1.4e-07 31.9 0.5 3.6e-07 30.6 0.5 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EGB04720.1 - 8.3e-05 22.3 0.0 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 CNH domain Vps39_1 PF10366.9 EGB04720.1 - 0.00088 19.5 0.0 0.0035 17.6 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 EGB04720.1 - 0.053 13.4 0.5 0.11 12.4 0.5 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS Trp_repressor PF01371.19 EGB04720.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Trp repressor protein WD40 PF00400.32 EGB04721.1 - 3.3e-43 144.8 23.2 4.2e-08 33.7 0.2 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04721.1 - 4.9e-25 87.7 0.7 7.8e-09 35.7 0.0 6.1 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB04721.1 - 4.3e-10 39.8 0.0 1.2e-05 25.3 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EGB04721.1 - 1.3e-08 34.5 0.8 2.3e-08 33.7 0.8 1.4 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 EGB04721.1 - 1.4e-06 27.5 0.0 0.077 11.9 0.0 3.2 3 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGB04721.1 - 0.00099 18.5 0.3 0.045 13.1 0.0 2.6 2 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 EGB04721.1 - 0.023 12.7 0.0 0.41 8.6 0.0 2.5 3 0 0 3 3 3 0 IKI3 family Nucleoporin_N PF08801.11 EGB04721.1 - 0.039 12.7 0.0 0.61 8.8 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 EGB04721.1 - 0.059 12.0 0.4 8.2 4.9 0.1 3.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 EGB04721.1 - 0.06 13.3 2.4 1.5 8.8 0.0 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 EGB04721.1 - 0.2 10.7 0.5 26 3.7 0.0 3.2 4 0 0 4 4 4 0 Coatomer WD associated region Ras PF00071.22 EGB04722.1 - 1.3e-35 122.4 0.0 1.6e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB04722.1 - 4.3e-30 104.4 0.0 5.7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB04722.1 - 3.9e-12 46.0 0.0 6e-12 45.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGB04722.1 - 1.3e-06 28.1 0.0 0.00063 19.3 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGB04722.1 - 0.00076 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGB04722.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGB04722.1 - 0.042 13.7 0.0 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 EGB04722.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ephrin_rec_like PF07699.13 EGB04723.1 - 4.2e-06 26.4 15.3 3.2e-05 23.6 3.4 3.9 2 1 3 5 5 5 4 Putative ephrin-receptor like NCD3G PF07562.14 EGB04723.1 - 0.036 14.1 14.7 0.2 11.7 3.5 3.3 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DHHC PF01529.20 EGB04724.1 - 6.1e-26 91.1 10.1 6.1e-26 91.1 10.1 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Imm17 PF15562.6 EGB04724.1 - 0.15 11.9 1.7 7.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Immunity protein 17 PH_15 PF17339.2 EGB04725.1 - 0.11 12.4 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 PH domain Ndr PF03096.14 EGB04725.1 - 0.12 11.1 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 Ndr family DUF5333 PF17267.2 EGB04725.1 - 0.68 10.1 2.9 0.76 10.0 1.2 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5333) SapB_1 PF05184.15 EGB04725.1 - 4.6 7.3 7.7 35 4.5 0.1 3.7 3 0 0 3 3 3 0 Saposin-like type B, region 1 Pantoate_transf PF02548.15 EGB04726.1 - 1.2e-92 310.0 2.0 1.4e-92 309.7 2.0 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 EGB04726.1 - 0.0078 16.1 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF21 PF01595.20 EGB04727.1 - 1.4e-22 80.2 0.1 2.2e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGB04727.1 - 4e-18 65.6 0.8 2e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.17 EGB04727.1 - 2.6e-13 49.8 0.0 6.9e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain Methyltransf_11 PF08241.12 EGB04727.1 - 0.11 13.1 0.0 0.6 10.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Sec20 PF03908.13 EGB04729.1 - 0.00022 21.1 0.4 0.0004 20.2 0.4 1.4 1 1 0 1 1 1 1 Sec20 V-SNARE PF05008.15 EGB04729.1 - 0.069 13.5 3.7 0.54 10.7 0.1 2.6 2 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Proteasome PF00227.26 EGB04730.1 - 1.1e-24 87.0 0.0 1.3e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TTL PF03133.15 EGB04731.1 - 4.8e-73 245.9 0.0 6.6e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB04731.1 - 2.5e-08 33.5 0.0 0.00015 21.1 0.0 3.2 2 2 2 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGB04731.1 - 4.5e-05 22.9 0.0 0.0058 15.9 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EGB04731.1 - 0.00018 21.6 0.1 0.026 14.6 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain GPS PF01825.21 EGB04731.1 - 0.17 12.4 0.1 0.85 10.2 0.0 2.1 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif tRNA-synt_1c PF00749.21 EGB04732.1 - 3.5e-95 318.5 0.0 4.8e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DEAD PF00270.29 EGB04734.1 - 1.8e-45 154.9 0.1 2.8e-45 154.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB04734.1 - 7.7e-26 90.6 0.2 1e-24 87.0 0.1 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB04734.1 - 5.2e-05 23.3 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGB04734.1 - 0.0019 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB04734.1 - 0.0058 16.9 0.1 0.02 15.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB04734.1 - 0.0063 16.9 0.2 0.014 15.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EGB04734.1 - 0.035 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TniB PF05621.11 EGB04734.1 - 0.063 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 EGB04734.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF2075 PF09848.9 EGB04734.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CTP_transf_like PF01467.26 EGB04735.1 - 8.2e-10 39.0 0.3 4e-09 36.8 0.0 2.3 3 0 0 3 3 3 1 Cytidylyltransferase-like PTCB-BRCT PF12738.7 EGB04735.1 - 1.1e-08 34.9 0.1 3.2e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EGB04735.1 - 0.065 13.6 0.0 0.43 11.0 0.0 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain zf-C3HC4_3 PF13920.6 EGB04736.1 - 0.0023 17.7 0.4 0.0023 17.7 0.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MazG_C PF18722.1 EGB04736.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 MazG C-terminal domain Adaptin_N PF01602.20 EGB04737.1 - 2e-116 389.6 13.0 2.6e-116 389.3 13.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGB04737.1 - 4.3e-17 62.4 0.6 7.8e-17 61.6 0.6 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGB04737.1 - 3.6e-12 46.6 5.4 1.1e-05 25.5 0.0 3.5 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGB04737.1 - 4.8e-06 26.4 0.3 0.4 11.1 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EGB04737.1 - 9.1e-06 26.0 4.9 0.59 10.6 0.1 4.4 3 2 2 5 5 5 3 HEAT repeats Proteasom_PSMB PF10508.9 EGB04737.1 - 0.065 11.7 5.5 0.038 12.5 3.1 1.8 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 EGB04737.1 - 0.067 13.3 1.5 0.43 10.7 0.2 3.2 3 1 1 4 4 4 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 EGB04737.1 - 0.17 12.5 1.6 13 6.4 0.0 3.4 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Pox_A28 PF04584.14 EGB04738.1 - 0.047 13.9 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A28 family UVR PF02151.19 EGB04739.1 - 5e-05 22.9 6.8 0.05 13.4 3.4 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif DUF2007 PF09413.10 EGB04739.1 - 0.37 11.0 4.4 2.9 8.1 0.1 3.3 3 1 1 4 4 4 0 Putative prokaryotic signal transducing protein Glyco_transf_34 PF05637.12 EGB04740.1 - 0.031 14.0 0.2 0.18 11.5 0.2 2.1 1 1 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family ETF_QO PF05187.13 EGB04741.1 - 7.5e-31 106.3 0.0 1.2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 EGB04741.1 - 8.1e-08 31.8 2.3 0.0012 18.0 3.5 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGB04741.1 - 2.7e-07 30.5 5.8 0.00017 21.3 1.5 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGB04741.1 - 2.6e-05 24.4 0.0 7.8e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGB04741.1 - 5.3e-05 22.6 0.0 8.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGB04741.1 - 9.3e-05 21.6 0.4 0.00019 20.6 0.3 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGB04741.1 - 0.00018 20.9 0.1 0.00026 20.3 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGB04741.1 - 0.00019 20.7 0.3 0.00042 19.6 0.2 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EGB04741.1 - 0.00022 21.7 0.7 0.28 11.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB04741.1 - 0.00044 19.1 0.2 0.0017 17.2 0.7 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 EGB04741.1 - 0.0007 19.6 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGB04741.1 - 0.0012 18.2 0.7 0.0017 17.7 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB04741.1 - 0.023 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_7 PF12838.7 EGB04741.1 - 0.046 14.3 2.5 0.11 13.2 2.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAD_oxidored PF12831.7 EGB04741.1 - 0.047 13.0 0.1 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AIRS PF00586.24 EGB04741.1 - 0.079 13.6 0.2 11 6.7 0.1 3.2 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain GIDA PF01134.22 EGB04741.1 - 0.24 10.5 0.9 0.32 10.0 0.9 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGB04741.1 - 2.8 6.7 6.1 0.68 8.7 1.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase Aldo_ket_red PF00248.21 EGB04742.1 - 1.8e-15 56.9 0.0 7.2e-07 28.7 0.0 2.8 2 1 1 3 3 3 2 Aldo/keto reductase family Nup88 PF10168.9 EGB04742.1 - 0.87 7.3 2.3 1.3 6.7 2.3 1.1 1 0 0 1 1 1 0 Nuclear pore component Ribosomal_S5 PF00333.20 EGB04743.1 - 5.1e-25 87.2 0.1 5.1e-25 87.2 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGB04743.1 - 4.8e-21 74.0 0.0 7.8e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EGB04743.1 - 2.2 8.9 15.3 5 7.8 15.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ubiquitin PF00240.23 EGB04744.1 - 1.4e-103 338.7 12.4 6.6e-34 115.5 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EGB04744.1 - 6.4e-49 163.7 14.7 8e-16 57.6 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB04744.1 - 3.8e-20 72.1 4.6 6.1e-05 23.4 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB04744.1 - 1.8e-13 50.2 2.1 0.007 16.3 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB04744.1 - 1.9e-12 47.3 0.7 0.03 14.4 0.0 4.0 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGB04744.1 - 9.7e-12 45.1 2.4 0.029 14.7 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 EGB04744.1 - 7.7e-11 42.5 0.2 0.1 13.2 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGB04744.1 - 4.3e-06 26.6 0.0 2.2 8.1 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EGB04744.1 - 9.3e-06 25.6 14.5 17 5.6 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF2870 PF11069.8 EGB04744.1 - 0.00033 21.0 0.0 20 5.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) TmoB PF06234.12 EGB04744.1 - 0.0012 18.9 3.0 15 5.8 0.1 3.8 3 3 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) Raf1_HTH PF18579.1 EGB04744.1 - 0.0022 17.6 0.5 26 4.6 0.0 3.3 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain DUF1940 PF09155.10 EGB04744.1 - 0.0054 16.9 2.8 21 5.2 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1940) UDP-g_GGTase PF06427.11 EGB04744.1 - 0.0066 16.6 0.9 7.5 6.7 0.0 3.0 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EGB04744.1 - 0.0087 15.5 0.0 16 4.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 EGB04744.1 - 0.013 15.7 0.4 49 4.2 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) CorA PF01544.18 EGB04744.1 - 0.043 13.1 0.2 46 3.2 0.0 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein ProRS-C_2 PF09181.10 EGB04744.1 - 0.093 12.9 0.7 1e+02 3.2 0.0 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal ORF11CD3 PF10549.9 EGB04744.1 - 0.1 12.7 1.2 62 3.8 0.0 3.9 6 0 0 6 6 3 0 ORF11CD3 domain Myosin_N PF02736.19 EGB04744.1 - 0.18 11.7 4.3 43 4.0 0.1 4.0 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 EGB04744.1 - 0.19 11.5 3.6 56 3.6 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain DMA PF03474.14 EGB04744.1 - 0.27 10.9 1.5 72 3.1 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif FlgD_ig PF13860.6 EGB04744.1 - 0.3 11.0 2.9 87 3.1 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain EF-hand_1 PF00036.32 EGB04745.1 - 2.3e-10 39.3 5.4 0.0013 18.1 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB04745.1 - 2.8e-10 39.3 1.1 0.11 12.5 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EGB04745.1 - 5.6e-09 36.3 1.1 2.1e-06 28.1 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB04745.1 - 5.6e-08 31.9 10.2 0.00012 21.4 0.2 3.8 4 0 0 4 4 4 3 EF hand Glyco_trans_1_4 PF13692.6 EGB04745.1 - 8.5e-08 32.7 0.0 2.5e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB04745.1 - 2e-07 30.7 0.1 5.9e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 WW PF00397.26 EGB04745.1 - 2.4e-05 24.3 1.8 6.4e-05 23.0 1.8 1.8 1 0 0 1 1 1 1 WW domain Dockerin_1 PF00404.18 EGB04745.1 - 0.00061 19.9 0.2 0.0014 18.8 0.2 1.6 1 0 0 1 1 1 1 Dockerin type I domain DUF2116 PF09889.9 EGB04745.1 - 0.16 12.0 0.3 0.44 10.6 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EF-hand_8 PF13833.6 EGB04745.1 - 0.54 10.2 6.0 6.1 6.8 0.4 3.4 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_4 PF12763.7 EGB04745.1 - 0.62 10.0 3.5 25 4.9 0.2 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand zf-ribbon_3 PF13248.6 EGB04745.1 - 0.64 9.5 2.2 1.2 8.6 2.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Glyco_trans_1_2 PF13524.6 EGB04745.1 - 1.5 9.3 0.0 1.5 9.3 0.0 3.3 3 0 0 3 3 2 0 Glycosyl transferases group 1 AAA PF00004.29 EGB04746.1 - 1.4e-40 138.8 0.0 3.1e-40 137.6 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB04746.1 - 5.4e-10 38.9 0.1 1.2e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGB04746.1 - 3.7e-06 27.2 0.0 9.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGB04746.1 - 7.4e-05 22.8 0.0 0.00042 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB04746.1 - 0.00096 19.6 0.1 0.0066 16.9 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB04746.1 - 0.0011 19.3 0.0 0.0075 16.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EGB04746.1 - 0.0056 16.4 0.0 0.027 14.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EGB04746.1 - 0.0057 15.8 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EGB04746.1 - 0.021 15.0 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB04746.1 - 0.033 13.7 0.0 0.078 12.5 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGB04746.1 - 0.036 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB04746.1 - 0.041 13.6 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB04746.1 - 0.055 14.0 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB04746.1 - 0.09 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGB04746.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EGB04746.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGB04747.1 - 1.5e-41 141.9 0.0 2.9e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGB04747.1 - 4.8e-11 42.5 0.1 1.2e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGB04747.1 - 1.7e-09 37.3 1.6 2e-09 37.1 0.2 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EGB04747.1 - 7.7e-08 32.9 0.4 4.9e-05 23.8 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 EGB04747.1 - 2.5e-06 27.5 0.1 2.6e-05 24.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGB04747.1 - 4.9e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB04747.1 - 7.8e-05 23.0 0.1 0.0092 16.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EGB04747.1 - 0.00017 21.8 0.0 0.00041 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EGB04747.1 - 0.00061 20.1 0.3 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 EGB04747.1 - 0.00087 18.9 0.2 0.0029 17.2 0.0 2.0 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 EGB04747.1 - 0.00094 19.7 0.2 0.0058 17.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGB04747.1 - 0.0013 18.5 0.1 0.0033 17.2 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein DUF815 PF05673.13 EGB04747.1 - 0.0013 17.9 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGB04747.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EGB04747.1 - 0.0015 17.8 0.0 0.0032 16.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGB04747.1 - 0.0021 17.5 0.0 0.005 16.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGB04747.1 - 0.0025 17.4 0.0 0.0062 16.1 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 EGB04747.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGB04747.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGB04747.1 - 0.012 15.4 0.1 0.042 13.6 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 EGB04747.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGB04747.1 - 0.024 14.4 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGB04747.1 - 0.031 13.8 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGB04747.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGB04747.1 - 0.038 13.3 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 KaiC Mac PF12464.8 EGB04747.1 - 0.039 14.2 0.1 2.1 8.7 0.0 3.1 3 0 0 3 3 3 0 Maltose acetyltransferase PhoH PF02562.16 EGB04747.1 - 0.047 13.1 0.1 0.096 12.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 EGB04747.1 - 0.048 13.4 0.4 0.097 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 EGB04747.1 - 0.049 12.7 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EGB04747.1 - 0.055 13.3 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB04747.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 1 0 NACHT domain PIF1 PF05970.14 EGB04747.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.27 EGB04747.1 - 0.14 12.6 0.0 0.44 11.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 EGB04747.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sulfotransfer_3 PF13469.6 EGB04748.1 - 1.5e-05 25.5 0.1 0.029 14.7 0.0 3.0 2 1 1 3 3 3 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB04748.1 - 0.0011 18.5 0.0 0.0034 16.9 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain NAD_synthase PF02540.17 EGB04749.1 - 2.6e-21 75.8 0.0 3.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 EGB04749.1 - 9.2e-10 38.3 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-LYAR PF08790.11 EGB04750.1 - 5.8e-12 45.3 4.0 5.8e-12 45.3 4.0 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EGB04750.1 - 0.00011 21.7 0.2 0.43 10.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 EGB04750.1 - 0.0045 17.4 6.7 0.14 12.7 0.3 2.7 2 1 0 2 2 2 2 Zinc finger, C2H2 type RL11D PF11088.8 EGB04750.1 - 0.12 12.7 1.3 0.16 12.3 1.3 1.2 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 zf-met PF12874.7 EGB04750.1 - 3.3 8.2 10.2 0.91 10.0 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Sgf11 PF08209.11 EGB04750.1 - 3.5 7.3 9.4 0.17 11.5 1.7 2.3 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) MitMem_reg PF13012.6 EGB04752.1 - 3.3e-29 101.6 0.6 5.9e-29 100.8 0.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGB04752.1 - 8.3e-29 100.0 0.0 1.7e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PHO4 PF01384.20 EGB04753.1 - 1.4e-93 313.6 19.8 1.7e-93 313.3 19.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF742 PF05331.11 EGB04753.1 - 0.048 13.5 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF742) Sulfotransfer_1 PF00685.27 EGB04754.1 - 1.7e-34 119.5 0.0 5.4e-34 117.9 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB04754.1 - 2.7e-08 34.5 0.2 6e-06 26.8 0.1 2.4 2 1 0 2 2 2 2 Sulfotransferase family Carboxyl_trans PF01039.22 EGB04755.1 - 8.1e-158 526.1 0.0 1.1e-157 525.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGB04755.1 - 1e-50 172.2 0.0 1.9e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGB04755.1 - 2.6e-30 105.2 0.0 5.8e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGB04755.1 - 1.5e-20 73.3 0.0 5.6e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGB04755.1 - 1.2e-10 41.0 0.1 4.1e-10 39.4 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ACC_central PF08326.12 EGB04755.1 - 1.9e-06 26.4 0.0 1.5e-05 23.5 0.0 1.9 1 1 0 2 2 2 1 Acetyl-CoA carboxylase, central region ATP-grasp PF02222.22 EGB04755.1 - 2.6e-06 27.1 0.0 5.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGB04755.1 - 3.9e-06 27.0 0.0 8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGB04755.1 - 6.1e-06 25.9 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus PE_PPE_C PF12484.8 EGB04755.1 - 8.7 7.3 11.2 9.5 7.2 7.2 3.4 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal Tyrosinase PF00264.20 EGB04756.1 - 4e-09 37.1 0.5 1.4e-08 35.3 0.3 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase Exostosin PF03016.15 EGB04756.1 - 6.8e-06 25.5 0.0 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Sel1 PF08238.12 EGB04756.1 - 2.1e-05 25.0 5.7 0.0019 18.8 0.0 4.2 4 0 0 4 4 4 2 Sel1 repeat Sulfotransfer_2 PF03567.14 EGB04756.1 - 0.00076 19.5 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family adh_short_C2 PF13561.6 EGB04757.1 - 6e-49 166.7 2.4 8.5e-49 166.2 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB04757.1 - 2.6e-46 157.5 0.9 3.6e-46 157.1 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB04757.1 - 1.7e-08 34.6 4.0 6.1e-07 29.5 4.0 2.1 1 1 0 1 1 1 1 KR domain ABATE PF07336.11 EGB04757.1 - 0.0015 19.2 2.8 0.011 16.5 0.5 2.1 2 0 0 2 2 2 1 Putative stress-induced transcription regulator Epimerase PF01370.21 EGB04757.1 - 0.0082 15.6 0.2 0.041 13.3 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PCP PF02429.15 EGB04757.1 - 0.1 12.9 0.2 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein Tic110 PF16940.5 EGB04757.1 - 0.36 9.3 2.5 0.51 8.8 2.5 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter PGM_PMM_I PF02878.16 EGB04757.1 - 1.6 8.4 3.7 2.6 7.8 0.6 2.6 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I ACC_epsilon PF13822.6 EGB04757.1 - 5 7.9 9.9 4.5 8.0 0.3 2.6 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit LRR_8 PF13855.6 EGB04758.1 - 2.9e-24 84.6 14.5 5.7e-08 32.4 0.8 4.0 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGB04758.1 - 5.1e-14 52.2 4.0 0.002 18.5 0.1 5.0 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB04758.1 - 2.2e-09 36.6 6.1 0.27 11.4 0.3 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EGB04758.1 - 1.8e-08 33.8 1.7 0.053 14.1 0.2 5.4 6 0 0 6 6 6 2 Leucine Rich Repeat Pkinase PF00069.25 EGB04759.1 - 1.5e-25 90.1 0.0 1.9e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04759.1 - 1.1e-12 47.9 0.0 1.7e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB04759.1 - 4.5e-06 25.7 0.0 4.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB04759.1 - 0.0038 17.2 0.0 0.0062 16.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB04759.1 - 0.19 11.0 0.3 0.39 10.0 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHHC PF01529.20 EGB04760.1 - 6e-23 81.4 9.6 6.4e-23 81.3 9.6 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1272 PF06906.11 EGB04760.1 - 0.16 12.1 6.7 0.28 11.3 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.6 EGB04760.1 - 0.77 9.7 9.2 2 8.3 9.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GRASP55_65 PF04495.14 EGB04761.1 - 2.7e-54 183.2 0.0 4.2e-38 130.8 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EGB04761.1 - 9.2e-08 31.8 1.1 0.0061 16.4 0.5 2.8 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EGB04761.1 - 3.8e-06 27.1 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EGB04761.1 - 0.0021 18.4 0.0 0.44 10.9 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Acetyltransf_1 PF00583.25 EGB04762.1 - 2.2e-16 60.1 0.0 3.1e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGB04762.1 - 1.2e-08 35.2 0.1 2.2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGB04762.1 - 3.2e-06 27.1 0.0 4.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EGB04762.1 - 0.0016 18.6 0.1 0.002 18.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB04762.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGB04762.1 - 0.048 13.8 0.1 0.084 13.0 0.1 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Sel1 PF08238.12 EGB04764.1 - 1.6e-37 127.1 31.3 5.1e-08 33.3 0.1 8.3 8 1 0 8 8 8 6 Sel1 repeat TPR_12 PF13424.6 EGB04764.1 - 0.0013 19.0 16.2 0.08 13.2 1.7 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat DUF935 PF06074.12 EGB04764.1 - 0.031 13.0 0.5 4.4 5.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF935) DUF1376 PF07120.11 EGB04764.1 - 0.065 13.5 0.1 19 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) DUF4376 PF14301.6 EGB04764.1 - 0.098 13.0 0.0 0.81 10.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4376) TPR_10 PF13374.6 EGB04764.1 - 0.34 10.8 0.1 0.34 10.8 0.1 5.2 8 0 0 8 8 8 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB04764.1 - 0.74 10.3 3.3 30 5.2 0.0 3.5 2 1 1 3 3 3 0 B12 binding domain TPR_8 PF13181.6 EGB04764.1 - 2.5 8.5 7.2 11 6.5 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04764.1 - 8.3 6.4 23.1 0.4 10.6 0.3 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_M19 PF01244.21 EGB04765.1 - 1.1e-101 340.2 0.0 1.3e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ribosomal_S3Ae PF01015.18 EGB04766.1 - 1.7e-92 308.5 1.6 2.1e-92 308.3 1.6 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family PhoLip_ATPase_C PF16212.5 EGB04767.1 - 7.9e-60 202.7 21.0 7.9e-60 202.7 21.0 2.1 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGB04767.1 - 1.3e-18 66.4 0.1 4.6e-18 64.7 0.1 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGB04767.1 - 9.1e-11 41.6 1.5 2e-09 37.3 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGB04767.1 - 1.4e-10 41.1 0.0 1.3e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGB04767.1 - 3.2e-06 27.6 6.6 0.0078 16.5 4.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGB04767.1 - 0.0095 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHMP_kinases_C PF08544.13 EGB04768.1 - 0.00044 20.6 0.3 0.0015 18.8 0.3 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal VHL PF01847.16 EGB04769.1 - 0.0033 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 VHL beta domain EF-hand_7 PF13499.6 EGB04770.1 - 1.1e-12 48.2 0.5 1.2e-12 48.1 0.5 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB04770.1 - 8.2e-12 43.8 4.0 1.1e-05 24.6 1.7 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB04770.1 - 3.7e-11 42.0 0.6 4.2e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB04770.1 - 8.5e-09 35.1 5.6 1.5e-05 24.7 1.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB04770.1 - 8.1e-07 28.3 3.6 0.0011 18.3 1.5 2.2 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGB04770.1 - 4.7e-05 23.6 0.0 5.1e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EGB04770.1 - 0.015 15.3 1.7 0.24 11.4 0.8 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand ACT_7 PF13840.6 EGB04771.1 - 6.2e-20 70.8 0.0 8.6e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 EGB04771.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 ACT domain Peptidase_A22B PF04258.13 EGB04772.1 - 3.4e-57 194.2 3.3 3.7e-57 194.0 3.3 1.0 1 0 0 1 1 1 1 Signal peptide peptidase Tox-HNH-HHH PF15637.6 EGB04772.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif SPP PF06550.11 EGB04772.1 - 4.6 6.6 12.8 0.23 10.9 4.8 2.3 2 1 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease AAA_28 PF13521.6 EGB04774.1 - 7.5e-27 94.6 0.3 1e-26 94.1 0.3 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGB04774.1 - 5.6e-05 22.7 0.0 8.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MeaB PF03308.16 EGB04774.1 - 0.0029 16.6 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGB04774.1 - 0.0054 16.6 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.6 EGB04774.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EGB04774.1 - 0.041 14.0 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 EGB04774.1 - 0.053 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DAP3 PF10236.9 EGB04774.1 - 0.054 12.6 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 EGB04774.1 - 0.1 13.2 0.4 0.2 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EGB04774.1 - 0.15 11.7 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGB04774.1 - 0.62 10.5 2.1 1.2 9.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain Glyco_hydro_47 PF01532.20 EGB04775.1 - 1.2e-88 298.1 0.0 1.4e-88 297.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Gmx_para_CXXCG PF09535.10 EGB04775.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) Kinesin PF00225.23 EGB04776.1 - 1.5e-99 333.1 0.0 1.7e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB04776.1 - 5.2e-22 78.4 0.0 1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Proteasome PF00227.26 EGB04777.1 - 9.6e-43 145.9 0.0 1.2e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB04777.1 - 1.6e-14 53.2 0.1 2.9e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sugar_tr PF00083.24 EGB04778.1 - 7.4e-61 206.4 18.4 7.2e-41 140.5 5.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGB04778.1 - 1.5e-16 60.3 38.9 2.9e-09 36.3 20.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sel1 PF08238.12 EGB04779.1 - 1.8e-49 165.0 36.6 1.2e-10 41.6 0.0 9.5 9 0 0 9 9 9 8 Sel1 repeat TPR_12 PF13424.6 EGB04779.1 - 9.7e-05 22.6 14.6 0.13 12.6 0.0 6.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04779.1 - 0.0046 16.7 0.2 0.099 12.5 0.1 7.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGB04779.1 - 0.0057 16.6 6.7 0.19 11.8 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB04779.1 - 0.018 14.9 15.4 0.21 11.5 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF410 PF04190.13 EGB04779.1 - 0.025 14.4 1.0 0.92 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_8 PF13181.6 EGB04779.1 - 0.19 12.0 11.4 1.2 9.5 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1952 PF09189.10 EGB04779.1 - 0.2 11.5 0.9 44 4.0 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1952) TPR_7 PF13176.6 EGB04779.1 - 3.5 7.9 8.4 46 4.4 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat GAS PF13851.6 EGB04780.1 - 9.5e-05 21.8 0.4 0.00016 21.1 0.1 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4250 PF14056.6 EGB04780.1 - 0.018 15.0 1.1 0.065 13.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) UPF0242 PF06785.11 EGB04780.1 - 0.06 13.5 2.7 0.076 13.1 2.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lectin_N PF03954.14 EGB04780.1 - 0.083 12.6 0.3 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.12 EGB04780.1 - 0.59 10.2 12.4 0.39 10.8 7.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EF-hand_1 PF00036.32 EGB04781.1 - 8.2e-08 31.3 2.2 6.2e-06 25.4 0.9 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB04781.1 - 2.7e-07 31.0 0.7 2.8e-07 30.9 0.7 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB04781.1 - 4.5e-07 29.3 1.3 0.0011 18.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB04781.1 - 9.9e-06 25.3 0.6 1.1e-05 25.2 0.6 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB04781.1 - 5.1e-05 22.6 1.6 0.00033 20.0 0.7 2.1 2 0 0 2 2 2 1 EF hand LTV PF04180.14 EGB04782.1 - 1.6e-11 44.6 16.1 1.4e-05 25.0 14.9 3.4 1 1 1 2 2 2 2 Low temperature viability protein Ion_trans PF00520.31 EGB04783.1 - 1e-58 198.5 24.3 1.6e-33 116.0 11.1 2.5 2 1 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 EGB04783.1 - 1.6e-07 30.4 23.7 0.00087 18.1 2.8 4.3 3 1 1 4 4 4 4 Polycystin cation channel Trypan_PARP PF05887.11 EGB04783.1 - 0.00061 19.8 11.8 0.0018 18.2 11.8 1.8 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 EGB04783.1 - 0.051 12.7 4.6 0.084 12.0 4.6 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF747 PF05346.11 EGB04783.1 - 0.08 12.4 0.9 5.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic membrane protein family AGTRAP PF06396.11 EGB04783.1 - 0.12 12.1 1.5 0.37 10.6 1.5 1.8 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF962 PF06127.11 EGB04783.1 - 0.76 9.9 4.4 2 8.6 0.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF962) DUF3742 PF12553.8 EGB04783.1 - 1.1 9.4 5.8 8.8 6.5 2.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) TonB_N PF16031.5 EGB04783.1 - 3 8.4 18.2 7.5 7.1 18.2 1.6 1 0 0 1 1 1 0 TonB polyproline region ABC1 PF03109.16 EGB04784.1 - 1.4e-22 80.0 0.0 2.8e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Acetyltransf_1 PF00583.25 EGB04784.1 - 6.7e-09 36.0 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGB04784.1 - 1.7e-08 34.5 0.0 3.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cupin_8 PF13621.6 EGB04784.1 - 1.4e-07 31.5 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain Acetyltransf_7 PF13508.7 EGB04784.1 - 4.4e-07 30.2 0.0 9.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AraC_binding PF02311.19 EGB04784.1 - 0.032 14.1 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain JmjC PF02373.22 EGB04784.1 - 0.034 14.6 0.1 0.15 12.5 0.0 2.1 2 1 0 2 2 2 0 JmjC domain, hydroxylase FR47 PF08445.10 EGB04784.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein Cupin_2 PF07883.11 EGB04784.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Cupin domain AAA PF00004.29 EGB04785.1 - 1.3e-17 64.5 0.0 1.7e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGB04785.1 - 7.2e-05 22.1 0.0 9.1e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGB04785.1 - 0.0013 18.8 0.0 0.004 17.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EGB04785.1 - 0.0021 18.6 0.0 0.0026 18.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB04785.1 - 0.003 17.9 0.1 0.0088 16.4 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EGB04785.1 - 0.0041 17.1 0.2 0.95 9.4 0.0 2.1 1 1 1 2 2 2 2 NACHT domain AAA_33 PF13671.6 EGB04785.1 - 0.043 14.0 0.0 0.085 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EGB04785.1 - 0.046 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 EGB04785.1 - 0.056 12.7 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EGB04785.1 - 0.061 13.1 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGB04785.1 - 0.065 13.3 0.1 0.094 12.8 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EGB04785.1 - 0.069 13.7 0.0 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB04785.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 RsgA GTPase ITI_HC_C PF06668.12 EGB04785.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Viral_helicase1 PF01443.18 EGB04785.1 - 0.11 12.2 0.2 0.31 10.8 0.1 1.7 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EGB04785.1 - 0.11 11.8 0.1 0.54 9.6 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 EGB04785.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB04785.1 - 0.13 12.6 0.2 1.9 8.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF1826 PF08856.11 EGB04786.1 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1826) ATP-grasp_2 PF08442.10 EGB04786.1 - 0.00015 21.4 0.0 0.00031 20.4 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain NOA36 PF06524.12 EGB04786.1 - 6.5 6.0 9.1 12 5.1 9.1 1.3 1 0 0 1 1 1 0 NOA36 protein Citrate_bind PF16114.5 EGB04787.1 - 7.5e-83 276.4 0.0 1.4e-82 275.5 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 EGB04787.1 - 3.8e-18 65.7 0.0 1.7e-16 60.3 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EGB04787.1 - 6.9e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EGB04787.1 - 3.6e-06 27.6 0.0 1.2e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 EGB04787.1 - 0.00066 19.3 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain AA_kinase PF00696.28 EGB04788.1 - 3.2e-22 79.3 0.3 6.1e-22 78.4 0.3 1.4 1 1 0 1 1 1 1 Amino acid kinase family DUF2866 PF11065.8 EGB04788.1 - 0.028 14.4 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) PDEase_I PF00233.19 EGB04789.1 - 6.5e-62 209.3 0.0 8.2e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Exo_endo_phos PF03372.23 EGB04790.1 - 1.8e-15 57.1 0.0 4.9e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cupin_4 PF08007.12 EGB04791.1 - 1.5e-47 162.6 0.0 2.4e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB04791.1 - 0.036 13.8 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain E1_dh PF00676.20 EGB04792.1 - 5.8e-44 150.2 0.0 6.9e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGB04792.1 - 6.2e-05 22.8 0.2 0.0026 17.5 0.0 2.8 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EGB04792.1 - 0.012 14.9 0.0 0.075 12.2 0.0 1.8 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DUF190 PF02641.15 EGB04792.1 - 0.097 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 Transketolase_C PF02780.20 EGB04793.1 - 5.9e-25 87.5 0.1 1.1e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EGB04793.1 - 6.6e-15 55.2 0.0 9.8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Aminotran_4 PF01063.19 EGB04794.1 - 7.8e-25 88.0 0.0 9.8e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Aldo_ket_red PF00248.21 EGB04795.1 - 1e-43 149.6 0.0 1.7e-43 148.9 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.26 EGB04796.1 - 3.3e-35 120.8 0.0 3.7e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGB04796.1 - 0.0015 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Carbam_trans_C PF16861.5 EGB04798.1 - 2.9e-45 153.9 0.0 5.3e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 EGB04798.1 - 4e-12 46.5 1.6 0.00012 21.9 0.3 3.0 3 0 0 3 3 3 3 Carbamoyltransferase N-terminus PRIMA1 PF16101.5 EGB04798.1 - 0.8 9.8 2.6 2 8.5 2.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Zeta_toxin PF06414.12 EGB04799.1 - 5.3e-19 68.3 0.0 1.9e-18 66.5 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EGB04799.1 - 4.7e-05 23.6 0.5 0.00028 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB04799.1 - 0.065 13.8 0.0 0.29 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Sigma70_ner PF04546.13 EGB04799.1 - 2.3 8.1 7.8 21 4.9 4.2 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Ion_trans PF00520.31 EGB04800.1 - 5e-30 104.5 5.2 1.2e-29 103.3 5.2 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB04800.1 - 5.1e-09 36.0 5.1 5.1e-09 36.0 5.1 3.2 3 0 0 3 3 3 1 Ion channel DUF2232 PF09991.9 EGB04800.1 - 0.00082 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) SPICE PF15678.5 EGB04800.1 - 0.0071 15.7 3.1 0.012 15.0 3.1 1.2 1 0 0 1 1 1 1 Centriole duplication and mitotic chromosome congression DUF2102 PF09875.9 EGB04800.1 - 0.019 14.7 3.0 0.046 13.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) DUF3899 PF13038.6 EGB04800.1 - 0.16 12.5 2.3 22 5.7 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) dCMP_cyt_deam_1 PF00383.23 EGB04801.1 - 0.0065 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DDDD PF10161.9 EGB04801.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative mitochondrial precursor protein GT87 PF09594.10 EGB04801.1 - 2.9 7.6 10.2 0.21 11.3 5.5 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 87 Glyco_transf_25 PF01755.17 EGB04802.1 - 3.5e-09 36.8 0.0 8.2e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DEAD PF00270.29 EGB04803.1 - 1e-47 162.1 0.0 2e-47 161.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB04803.1 - 2.1e-30 105.3 0.0 6.3e-30 103.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DnaJ PF00226.31 EGB04804.1 - 5.4e-21 74.5 0.4 6e-21 74.3 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain Sigma70_ner PF04546.13 EGB04804.1 - 0.052 13.4 0.2 0.06 13.2 0.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CAP_GLY PF01302.25 EGB04805.1 - 3.9e-21 74.8 0.5 4.2e-21 74.7 0.5 1.0 1 0 0 1 1 1 1 CAP-Gly domain CLASP_N PF12348.8 EGB04806.1 - 2.6e-11 43.6 0.0 4.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal RTP1_C1 PF10363.9 EGB04806.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EGB04806.1 - 0.059 13.7 0.1 0.059 13.7 0.1 5.5 6 0 0 6 6 6 0 HEAT repeat Ldh_1_N PF00056.23 EGB04807.1 - 4.4e-48 163.0 0.1 6.2e-48 162.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGB04807.1 - 3.1e-47 160.6 0.1 6.6e-47 159.6 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EGB04807.1 - 0.0025 16.9 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EGB04807.1 - 0.047 14.1 0.3 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Acyl_transf_1 PF00698.21 EGB04808.1 - 3.1e-23 82.8 0.6 3.9e-23 82.5 0.6 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 EGB04808.1 - 0.011 15.4 0.3 0.35 10.6 0.3 2.2 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis RRM_1 PF00076.22 EGB04809.1 - 4.2e-19 68.1 0.0 5.2e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB04809.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 EGB04809.1 - 0.019 14.6 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-3_zeta PF05091.12 EGB04810.1 - 3.3e-185 617.0 0.0 3.7e-185 616.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GHMP_kinases_N PF00288.26 EGB04811.1 - 1.5e-10 41.1 0.1 3.1e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGB04811.1 - 2.3e-09 37.5 0.0 5.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal RRM_1 PF00076.22 EGB04812.1 - 4.5e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VHL PF01847.16 EGB04812.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 VHL beta domain Ank_5 PF13857.6 EGB04813.1 - 1.4e-11 44.4 3.8 7.2e-05 23.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB04813.1 - 3.5e-09 37.1 0.0 0.0003 21.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB04813.1 - 3.2e-07 30.8 0.3 0.0019 18.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB04813.1 - 2.2e-05 24.5 0.6 0.091 13.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGB04813.1 - 0.099 13.1 3.6 2.8 8.6 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat SPRY PF00622.28 EGB04814.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Pelovaterin PF17859.1 EGB04814.1 - 0.073 13.3 2.2 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 Pelovaterin Chloroa_b-bind PF00504.21 EGB04815.1 - 2.3e-25 90.0 0.0 4.1e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Myb_DNA-binding PF00249.31 EGB04816.1 - 1.5e-44 149.9 15.3 8.4e-11 41.9 0.2 4.8 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB04816.1 - 1.2e-32 111.9 2.8 6.7e-08 32.7 0.1 4.5 4 0 0 4 4 4 4 Myb-like DNA-binding domain Bromodomain PF00439.25 EGB04816.1 - 2.4e-15 56.4 0.0 5.7e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Myb_DNA-bind_7 PF15963.5 EGB04816.1 - 0.0089 15.9 1.8 7.9 6.5 0.0 4.1 3 1 0 3 3 3 1 Myb DNA-binding like Sel1 PF08238.12 EGB04816.1 - 0.028 15.1 0.6 0.028 15.1 0.6 3.1 3 0 0 3 3 3 0 Sel1 repeat Lumazine_bd_2 PF12893.7 EGB04816.1 - 0.086 13.5 1.3 31 5.3 0.0 3.4 3 1 0 3 3 3 0 Putative lumazine-binding SPRY PF00622.28 EGB04816.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 SPRY domain DUF763 PF05559.11 EGB04816.1 - 0.5 9.5 6.0 1.7 7.7 3.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF763) HTH_32 PF13565.6 EGB04816.1 - 0.8 10.4 9.0 4 8.1 0.1 4.7 3 1 0 3 3 3 0 Homeodomain-like domain Borrelia_P83 PF05262.11 EGB04816.1 - 6.4 5.1 20.8 12 4.2 20.8 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Ammonium_transp PF00909.21 EGB04817.1 - 5.6e-110 367.8 19.2 2.1e-109 365.9 19.2 1.7 1 1 0 1 1 1 1 Ammonium Transporter Family DUF3188 PF11384.8 EGB04817.1 - 0.022 14.5 0.1 0.062 13.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Lig_chan PF00060.26 EGB04818.1 - 1.9e-13 50.5 0.0 6.7e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 EGB04818.1 - 7.1e-06 25.6 0.0 2.2e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 EGB04818.1 - 0.0089 15.6 0.0 0.068 12.7 0.0 2.1 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system Abhydrolase_6 PF12697.7 EGB04819.1 - 1.5e-09 38.8 13.1 1.5e-09 38.8 13.1 5.8 1 1 4 5 5 5 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB04819.1 - 3.1e-09 36.4 1.4 1.2e-08 34.5 1.4 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PfkB PF00294.24 EGB04819.1 - 1.1e-08 34.8 0.0 2e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Abhydrolase_1 PF00561.20 EGB04819.1 - 2.2e-08 34.1 0.2 6.4e-08 32.5 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Aldolase PF01081.19 EGB04819.1 - 9.8e-08 31.6 0.3 2.7e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 KDPG and KHG aldolase Thioesterase PF00975.20 EGB04819.1 - 0.0011 19.1 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain CAP_N PF01213.19 EGB04819.1 - 4.6 6.6 4.5 7.2 6.0 4.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal tRNA_U5-meth_tr PF05958.11 EGB04820.1 - 2.4e-102 342.5 0.0 2.7e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EGB04820.1 - 3.3e-05 24.5 0.2 0.00011 22.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB04820.1 - 6.9e-05 23.4 0.1 0.00063 20.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB04820.1 - 0.00068 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB04820.1 - 0.0015 18.1 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGB04820.1 - 0.0044 17.7 0.0 0.0076 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGB04820.1 - 0.0077 15.8 0.0 0.016 14.8 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase NodS PF05401.11 EGB04820.1 - 0.046 13.3 0.5 0.42 10.2 0.1 2.2 1 1 1 2 2 2 0 Nodulation protein S (NodS) SNARE PF05739.19 EGB04821.1 - 0.015 15.3 2.0 0.02 14.9 1.2 1.8 2 1 0 2 2 2 0 SNARE domain HU-CCDC81_bac_2 PF18175.1 EGB04821.1 - 0.089 12.7 0.5 9.6 6.2 0.1 2.1 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Aldo_ket_red PF00248.21 EGB04823.1 - 7e-38 130.5 0.0 1.2e-37 129.7 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Mago-bind PF09282.10 EGB04824.1 - 6.7e-07 29.1 1.7 1.6e-06 27.8 1.7 1.7 1 0 0 1 1 1 1 Mago binding Ank_5 PF13857.6 EGB04824.1 - 9e-06 25.9 0.9 2.3e-05 24.6 0.4 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB04824.1 - 0.00011 22.7 0.1 0.00022 21.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB04824.1 - 0.0069 16.8 0.4 0.54 11.0 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGB04824.1 - 0.0075 16.7 0.1 0.066 13.7 0.5 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGB04824.1 - 0.017 15.7 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) FANC_SAP PF18081.1 EGB04825.1 - 0.063 13.5 2.5 3.7 7.8 0.4 3.5 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain KH_6 PF15985.5 EGB04826.1 - 3.6e-12 46.4 0.0 5.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 KH domain DnaJ_C PF01556.18 EGB04827.1 - 1.4e-33 116.1 0.0 1.9e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB04827.1 - 1.8e-27 95.2 1.1 3e-27 94.5 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain LprI PF07007.12 EGB04827.1 - 0.058 14.0 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Lysozyme inhibitor LprI DUF3106 PF11304.8 EGB04827.1 - 0.31 11.5 1.3 2.4 8.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Got1 PF04178.12 EGB04828.1 - 2.7e-09 37.5 5.4 3.1e-09 37.2 5.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2065 PF09838.9 EGB04828.1 - 1.1 9.3 5.9 1.9 8.5 1.1 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) DUF3040 PF11239.8 EGB04828.1 - 2.9 8.2 9.8 0.35 11.2 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Pkinase_Tyr PF07714.17 EGB04829.1 - 2.5e-46 158.1 0.0 2.8e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB04829.1 - 3.5e-31 108.5 0.0 4e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGB04829.1 - 0.002 17.5 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB04829.1 - 0.0062 15.4 0.0 0.0078 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB04829.1 - 0.0068 15.8 0.0 0.009 15.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB04829.1 - 0.092 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tctex-1 PF03645.13 EGB04831.1 - 2.5e-19 69.4 0.2 4.1e-19 68.7 0.2 1.3 1 0 0 1 1 1 1 Tctex-1 family PRKCSH PF07915.13 EGB04831.1 - 1.1e-11 45.6 0.0 7e-05 23.8 0.1 2.8 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGB04831.1 - 0.013 15.1 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein ThiF PF00899.21 EGB04832.1 - 1.1e-56 192.0 0.0 1.6e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGB04832.1 - 0.00095 19.7 0.0 0.0029 18.1 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.14 EGB04832.1 - 0.0034 17.0 0.1 0.0054 16.3 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGB04832.1 - 0.021 15.1 0.1 0.092 13.0 0.2 2.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF760 PF05542.11 EGB04833.1 - 1.1e-38 131.4 1.0 2.8e-18 66.0 1.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF760) DUF4148 PF13663.6 EGB04834.1 - 6.9 6.9 7.4 0.24 11.6 0.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Amidohydro_1 PF01979.20 EGB04835.1 - 1.1e-08 34.8 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGB04835.1 - 2.3e-07 30.6 0.0 2.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Peptidase_M17 PF00883.21 EGB04836.1 - 1e-96 323.9 3.0 1.4e-96 323.4 3.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain PALP PF00291.25 EGB04837.1 - 2.1e-47 162.0 7.5 2.6e-47 161.6 7.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glycos_transf_3 PF00591.21 EGB04838.1 - 1.3e-79 267.4 0.0 1.7e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EGB04838.1 - 7e-14 51.4 0.0 1.6e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain EMG1 PF03587.14 EGB04839.1 - 9.8e-70 234.2 0.0 1.2e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase TB2_DP1_HVA22 PF03134.19 EGB04840.1 - 5.1e-10 39.2 0.1 9.2e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PT PF04886.12 EGB04840.1 - 0.00047 19.6 34.9 0.017 14.6 21.4 2.6 1 1 1 2 2 2 2 PT repeat VWA_2 PF13519.6 EGB04840.1 - 0.0024 18.5 0.0 0.0049 17.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGB04840.1 - 0.055 13.7 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain ABC2_membrane PF01061.24 EGB04841.1 - 1.9e-27 96.1 0.0 2.4e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGB04841.1 - 8e-21 75.0 0.0 1.3e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB04841.1 - 1e-05 25.5 0.0 0.11 12.3 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGB04841.1 - 1.1e-05 25.1 1.5 0.00018 21.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EGB04841.1 - 0.00042 20.0 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB04841.1 - 0.0013 19.2 0.0 0.0021 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGB04841.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGB04841.1 - 0.0091 16.4 0.1 0.0091 16.4 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 EGB04841.1 - 0.017 14.5 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB04841.1 - 0.037 13.7 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB04841.1 - 0.053 13.4 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain ABC2_membrane_3 PF12698.7 EGB04841.1 - 0.17 10.9 0.3 0.26 10.4 0.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein BATS PF06968.13 EGB04842.1 - 4.8e-17 61.9 0.0 1.4e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EGB04842.1 - 4.6e-14 53.2 0.1 7e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Sugar_tr PF00083.24 EGB04843.1 - 4.7e-67 226.8 4.7 2.4e-65 221.2 4.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB04843.1 - 1.1e-19 70.6 32.5 1e-11 44.4 13.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DOT1 PF08123.13 EGB04843.1 - 1.5e-14 54.1 0.0 3.7e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 MFS_Mycoplasma PF07672.13 EGB04843.1 - 0.033 13.5 0.2 0.35 10.1 0.5 2.0 2 0 0 2 2 2 0 Mycoplasma MFS transporter Methyltransf_31 PF13847.6 EGB04843.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGB04843.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Nha1_C PF08619.10 EGB04843.1 - 7 5.7 15.1 12 5.0 15.1 1.4 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Pkinase PF00069.25 EGB04844.1 - 2.5e-25 89.3 0.0 1.2e-24 87.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04844.1 - 1e-12 47.9 0.0 2.6e-10 40.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGB04844.1 - 0.00043 19.7 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGB04844.1 - 0.0022 18.0 0.2 0.0022 18.0 0.2 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB04844.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4915 PF16261.5 EGB04844.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4915) Ribosomal_L12 PF00542.19 EGB04845.1 - 2.6e-14 53.3 0.1 3.9e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain HTH_22 PF13309.6 EGB04845.1 - 0.065 13.3 0.3 1.1 9.4 0.2 2.3 1 1 0 2 2 2 0 HTH domain EF-hand_1 PF00036.32 EGB04846.1 - 5.2e-12 44.4 1.0 3.8e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB04846.1 - 8e-09 34.6 5.1 2.2e-05 23.8 0.1 2.7 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB04846.1 - 2.2e-08 33.4 2.4 0.00038 20.1 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGB04846.1 - 5.3e-08 33.2 0.2 6.5e-08 32.9 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB04846.1 - 3.7e-07 29.9 2.0 0.02 14.8 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB04846.1 - 0.00036 20.8 0.0 0.00041 20.6 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain Rdx PF10262.9 EGB04847.1 - 3.4e-11 43.2 0.1 3.9e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Rdx family adh_short PF00106.25 EGB04848.1 - 2.8e-26 92.2 2.3 4.1e-26 91.7 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB04848.1 - 4.2e-17 62.5 1.2 5.9e-17 62.0 1.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB04848.1 - 0.00037 20.5 1.7 0.00085 19.3 1.7 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGB04848.1 - 0.0057 16.6 2.8 0.014 15.3 2.8 1.8 1 1 0 1 1 1 1 NAD(P)H-binding AP_endonuc_2 PF01261.24 EGB04849.1 - 0.0081 15.6 0.2 3.1 7.2 0.0 2.5 3 0 0 3 3 3 2 Xylose isomerase-like TIM barrel Ion_trans PF00520.31 EGB04850.1 - 9.7e-13 47.9 10.8 1.6e-12 47.2 10.8 1.3 1 0 0 1 1 1 1 Ion transport protein DUF4710 PF15828.5 EGB04850.1 - 0.017 15.2 0.2 0.046 13.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) RNA_polI_A34 PF08208.11 EGB04850.1 - 6.8 6.7 9.6 11 6.0 9.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Lipase_GDSL_2 PF13472.6 EGB04851.1 - 0.0031 17.9 3.7 0.02 15.3 2.7 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF480 PF04337.12 EGB04851.1 - 0.047 13.8 0.1 0.097 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 His_Phos_1 PF00300.22 EGB04852.1 - 1.7e-30 106.1 0.1 3.1e-22 79.2 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 EGB04853.1 - 1.8e-30 106.1 0.1 1.8e-24 86.6 0.2 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) GCK PF07802.11 EGB04853.1 - 0.21 12.0 0.2 1.1 9.7 0.1 2.0 2 0 0 2 2 2 0 GCK domain DUF389 PF04087.14 EGB04854.1 - 1.2e-26 93.5 12.6 1.2e-26 93.5 12.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF389) Zip PF02535.22 EGB04854.1 - 0.0075 15.5 2.8 0.013 14.7 2.8 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1269 PF06897.12 EGB04854.1 - 0.83 10.0 0.1 0.83 10.0 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Acyl_transf_3 PF01757.22 EGB04855.1 - 5.6e-20 71.7 25.0 5.6e-20 71.7 25.0 2.1 2 0 0 2 2 2 1 Acyltransferase family WD40 PF00400.32 EGB04856.1 - 4.2e-27 93.9 22.7 6.7e-09 36.2 0.0 6.5 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB04856.1 - 3.5e-13 49.6 0.9 0.12 12.7 0.0 5.2 2 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PALP PF00291.25 EGB04857.1 - 5.9e-62 209.7 12.2 7e-62 209.5 12.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 EGB04857.1 - 0.055 13.3 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PSD2 PF07624.11 EGB04857.1 - 0.15 11.8 0.0 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Glutaredoxin PF00462.24 EGB04858.1 - 2.3e-13 50.1 0.0 4.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 EGB04858.1 - 0.0046 17.2 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB04858.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GCV_T PF01571.21 EGB04859.1 - 4.2e-70 236.0 0.2 7.5e-70 235.2 0.0 1.5 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 EGB04859.1 - 1.6e-57 195.7 4.2 2.5e-56 191.8 1.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAO_M PF16350.5 EGB04859.1 - 4.6e-24 84.5 0.1 9.4e-24 83.5 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 EGB04859.1 - 4e-16 58.7 0.4 1.2e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EGB04859.1 - 7.4e-11 42.4 0.1 7.5e-10 39.1 0.0 2.2 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family FAD_binding_2 PF00890.24 EGB04859.1 - 1.1e-06 28.0 3.6 1.1e-06 28.0 3.6 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB04859.1 - 1.5e-06 27.7 0.4 0.00058 19.2 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB04859.1 - 1.9e-05 24.8 0.6 7.4e-05 22.9 0.6 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGB04859.1 - 6.8e-05 22.3 0.6 6.8e-05 22.3 0.6 1.7 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 EGB04859.1 - 0.00055 19.4 0.1 0.93 8.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_9 PF13454.6 EGB04859.1 - 0.0013 18.8 1.0 0.14 12.1 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGB04859.1 - 0.002 17.4 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB04859.1 - 0.0021 18.6 0.5 0.0066 17.0 0.5 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGB04859.1 - 0.0024 17.5 0.3 0.011 15.3 0.4 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EGB04859.1 - 0.0027 17.0 0.1 0.006 15.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGB04859.1 - 0.0035 16.5 1.0 0.3 10.1 0.8 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A KR PF08659.10 EGB04859.1 - 0.014 15.3 0.4 0.027 14.4 0.4 1.5 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 EGB04859.1 - 0.017 15.2 0.1 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EGB04859.1 - 0.071 13.0 0.3 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EGB04859.1 - 0.1 12.0 0.9 0.15 11.3 0.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGB04859.1 - 0.2 10.4 2.0 8 5.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Aldo_ket_red PF00248.21 EGB04860.1 - 6.4e-40 137.2 0.0 8.9e-38 130.1 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Flavoprotein PF02441.19 EGB04861.1 - 1.9e-44 151.2 0.1 2.7e-44 150.7 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein STI1 PF17830.1 EGB04861.1 - 3.2e-05 23.8 0.0 0.086 12.8 0.0 2.5 2 0 0 2 2 2 2 STI1 domain Pkinase PF00069.25 EGB04862.1 - 4.9e-66 222.8 0.0 5.9e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04862.1 - 9.9e-39 133.2 0.0 1.2e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGB04862.1 - 2.1e-06 28.3 0.1 3.4e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 EGB04862.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB04862.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like SET PF00856.28 EGB04863.1 - 1.6e-05 25.4 0.0 4.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 SET domain adh_short_C2 PF13561.6 EGB04864.1 - 1.8e-46 158.6 0.9 2.1e-46 158.4 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB04864.1 - 2.8e-29 102.0 0.3 3.2e-29 101.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB04864.1 - 6e-07 29.5 0.7 8.4e-07 29.1 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB04864.1 - 0.00034 20.1 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB04864.1 - 0.00059 19.8 1.9 0.0027 17.6 1.9 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGB04864.1 - 0.019 15.4 0.7 0.046 14.2 0.2 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EGB04864.1 - 0.035 13.2 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 EGB04864.1 - 0.067 13.3 0.2 0.14 12.3 0.2 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EGB04864.1 - 0.077 12.5 0.5 0.36 10.3 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family Nitroreductase PF00881.24 EGB04865.1 - 9.7e-19 68.0 0.0 1.2e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family GNT-I PF03071.15 EGB04867.1 - 1.5e-31 109.6 0.4 1.7e-31 109.5 0.4 1.0 1 0 0 1 1 1 1 GNT-I family SRCR PF00530.18 EGB04868.1 - 7e-55 183.7 5.6 2.2e-27 95.4 0.2 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EGB04868.1 - 3.8e-08 33.7 0.4 0.0088 16.6 0.0 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 EGB04868.1 - 0.0049 17.4 0.0 1.5 9.4 0.0 2.2 2 0 0 2 2 2 2 Hepsin, SRCR domain Pirin PF02678.16 EGB04869.1 - 4.1e-22 78.2 0.2 7e-22 77.5 0.2 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGB04869.1 - 4.9e-17 62.2 0.0 7.7e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Peptidase_C97 PF05903.14 EGB04870.1 - 6.3e-26 91.0 0.0 7.2e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EGB04870.1 - 0.058 13.7 0.0 0.084 13.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Ion_trans PF00520.31 EGB04871.1 - 6.8e-52 176.1 4.5 7.8e-52 175.9 4.5 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGB04871.1 - 0.044 12.5 12.8 2 7.0 2.2 3.1 3 0 0 3 3 3 0 Polycystin cation channel Adeno_E3_14_5 PF04834.12 EGB04871.1 - 2.3 8.8 4.2 0.78 10.3 0.1 2.3 3 0 0 3 3 3 0 Early E3 14.5 kDa protein Ion_trans PF00520.31 EGB04872.1 - 1.5e-44 152.1 2.2 2e-44 151.7 2.2 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGB04872.1 - 2.8e-09 36.2 5.7 1.7e-06 27.0 3.5 2.6 2 1 0 2 2 2 2 Polycystin cation channel EF-hand_1 PF00036.32 EGB04872.1 - 0.00056 19.3 0.8 0.0014 18.0 0.0 2.1 1 1 1 2 2 2 1 EF hand EF-hand_5 PF13202.6 EGB04872.1 - 0.0097 15.4 2.6 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 EF hand GPHH PF16905.5 EGB04872.1 - 0.027 14.2 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_7 PF13499.6 EGB04872.1 - 0.062 13.7 2.2 4.6 7.8 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EGB04872.1 - 0.068 13.1 0.0 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Aldedh PF00171.22 EGB04873.1 - 1.7e-79 267.5 0.3 1.9e-79 267.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HSP90 PF00183.18 EGB04874.1 - 1.2e-230 766.8 22.9 1.6e-230 766.4 22.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGB04874.1 - 2.2e-14 53.9 0.0 5.1e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGB04874.1 - 7.6e-11 42.0 0.2 2e-10 40.6 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sulfotransfer_3 PF13469.6 EGB04875.1 - 5.2e-14 53.2 0.3 9.2e-08 32.7 0.1 2.3 2 0 0 2 2 2 2 Sulfotransferase family NAD_binding_1 PF00175.21 EGB04876.1 - 9e-26 90.7 0.0 1.5e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 EGB04876.1 - 0.012 15.2 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_6 PF00970.24 EGB04876.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.11 EGB04876.1 - 0.14 12.4 0.0 0.53 10.5 0.0 1.9 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain SNF2_N PF00176.23 EGB04877.1 - 2e-30 105.7 0.1 3.7e-30 104.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB04877.1 - 5.8e-13 49.2 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB04877.1 - 4.1e-10 39.9 0.0 6.7e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB04877.1 - 0.00084 19.2 0.0 0.4 10.4 0.0 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 EGB04877.1 - 0.0079 16.2 0.0 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 Flavivirus DEAD domain Carboxyl_trans PF01039.22 EGB04877.1 - 0.047 12.3 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain Beta_helix PF13229.6 EGB04878.1 - 1.9e-16 60.3 28.0 4.2e-12 46.2 9.5 2.6 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EGB04878.1 - 1.4e-12 47.4 5.0 6.6e-08 32.1 0.8 2.2 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF5123 PF17161.4 EGB04878.1 - 0.00022 22.3 1.1 0.07 14.2 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF5123) Disaggr_assoc PF08480.10 EGB04878.1 - 0.019 14.9 9.5 0.59 10.0 1.0 3.3 1 1 2 3 3 3 0 Disaggregatase related KRTAP PF11759.8 EGB04878.1 - 0.098 13.2 148.3 1.8e+04 -110.2 148.3 7.1 1 1 0 1 1 1 0 Keratin-associated matrix Peptidase_C1 PF00112.23 EGB04879.1 - 1.1e-41 143.4 0.0 1.1e-41 143.3 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB04879.1 - 0.0072 15.2 0.0 0.034 12.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase C1-like family Acetyltransf_1 PF00583.25 EGB04880.1 - 8.5e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGB04880.1 - 3.2e-07 30.7 0.0 5.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGB04880.1 - 7.6e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB04880.1 - 6.7e-05 22.8 0.0 0.00041 20.3 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 EGB04880.1 - 0.00098 19.2 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EGB04880.1 - 0.0032 17.6 0.0 0.0096 16.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGB04880.1 - 0.034 14.8 0.0 0.14 12.9 0.0 1.8 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Baculo_p33 PF05214.12 EGB04880.1 - 0.041 13.6 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 Baculovirus P33 Apyrase PF06079.11 EGB04881.1 - 1.1e-73 248.0 0.0 1.3e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Apyrase EF-hand_1 PF00036.32 EGB04883.1 - 2.5e-24 83.0 3.4 3.4e-06 26.2 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGB04883.1 - 5.9e-23 79.3 3.4 1.1e-05 24.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB04883.1 - 4.4e-21 75.1 0.0 1.9e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB04883.1 - 2e-18 64.7 2.7 0.00097 18.9 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB04883.1 - 7.7e-18 64.1 4.8 2.4e-08 33.7 0.1 3.3 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB04883.1 - 9.5e-06 25.9 0.0 0.025 14.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGB04883.1 - 0.00048 20.0 0.1 2.9 7.9 0.0 3.1 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGB04883.1 - 0.0011 19.1 7.3 0.24 11.6 0.2 4.3 3 2 1 4 4 4 1 Dockerin type I domain EF-hand_9 PF14658.6 EGB04883.1 - 0.0038 17.5 0.0 1.4 9.3 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain VCBS PF13517.6 EGB04883.1 - 0.39 11.3 9.8 14 6.3 0.1 4.0 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Sel1 PF08238.12 EGB04884.1 - 4e-51 170.3 43.9 6.4e-09 36.2 0.2 10.2 10 0 0 10 10 10 7 Sel1 repeat TPR_3 PF07720.12 EGB04884.1 - 0.0076 16.2 9.5 2.3 8.3 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat AAA_lid_10 PF17872.1 EGB04884.1 - 0.013 15.6 0.1 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA lid domain Minor_tail_Z PF06763.11 EGB04884.1 - 0.025 14.4 0.4 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) DUF410 PF04190.13 EGB04884.1 - 0.026 14.3 3.1 2.4 7.9 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF410) TPR_8 PF13181.6 EGB04884.1 - 0.047 13.9 11.2 1.2 9.6 0.3 5.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5555 PF17710.1 EGB04884.1 - 0.56 9.7 5.3 1.7 8.1 0.2 2.8 1 1 1 3 3 3 0 Family of unknown function (DUF5555) TPR_12 PF13424.6 EGB04884.1 - 2.3 8.6 27.9 0.22 11.8 1.4 7.0 5 2 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB04884.1 - 4.6 7.3 23.0 0.85 9.6 0.4 6.7 9 0 0 9 9 9 0 Tetratricopeptide repeat Sulfotransfer_3 PF13469.6 EGB04885.1 - 1.1e-05 25.9 1.7 0.0092 16.4 1.2 3.2 2 1 0 2 2 2 1 Sulfotransferase family UPF0014 PF03649.13 EGB04886.1 - 1.2e-61 208.1 12.6 1.4e-61 208.0 12.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) zf-met PF12874.7 EGB04887.1 - 1.4e-06 28.5 0.7 2.6e-06 27.6 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGB04887.1 - 1.1e-05 25.6 0.3 3.3e-05 24.1 0.3 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 EGB04887.1 - 0.00043 20.3 0.9 0.0013 18.7 0.9 1.9 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-U1 PF06220.12 EGB04887.1 - 0.0014 18.3 0.6 0.0031 17.3 0.6 1.5 1 0 0 1 1 1 1 U1 zinc finger DUF4407 PF14362.6 EGB04887.1 - 1.2 8.4 8.0 0.12 11.7 4.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glyco_hydro_35 PF01301.19 EGB04888.1 - 3.7e-92 309.3 0.1 4.8e-92 309.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EGB04888.1 - 5.2e-09 35.9 0.1 1.4e-07 31.2 0.1 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 EGB04888.1 - 0.0014 19.2 0.0 0.0085 16.7 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Thioredoxin PF00085.20 EGB04889.1 - 1.2e-27 95.9 0.1 1.3e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGB04889.1 - 4.1e-07 30.1 0.0 6.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EGB04889.1 - 0.00082 18.8 0.0 0.00097 18.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF3228 PF11539.8 EGB04889.1 - 0.003 17.1 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Thioredoxin_3 PF13192.6 EGB04889.1 - 0.0041 17.1 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 EGB04889.1 - 0.0054 17.2 0.3 0.086 13.3 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGB04889.1 - 0.013 15.8 0.0 0.063 13.6 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like HyaE PF07449.11 EGB04889.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EGB04889.1 - 0.03 14.2 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 EGB04889.1 - 0.039 13.8 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF3717 PF12512.8 EGB04889.1 - 0.22 11.4 4.8 0.18 11.7 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) RF-1 PF00472.20 EGB04892.1 - 3.6e-15 55.9 0.9 5.2e-15 55.4 0.9 1.3 1 1 0 1 1 1 1 RF-1 domain F-box-like PF12937.7 EGB04893.1 - 0.0075 16.1 1.9 0.0075 16.1 1.9 1.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGB04893.1 - 0.28 11.1 1.5 0.42 10.5 1.5 1.3 1 0 0 1 1 1 0 F-box domain Kinesin PF00225.23 EGB04894.1 - 1.7e-85 286.9 0.0 1.9e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB04894.1 - 1e-22 80.7 0.0 3.4e-22 79.0 0.0 1.9 1 1 0 1 1 1 1 Microtubule binding AAA_30 PF13604.6 EGB04894.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain VCBS PF13517.6 EGB04895.1 - 5.8e-142 462.4 309.2 1.2e-10 41.8 7.8 27.8 11 7 19 30 30 30 28 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Laminin_G_3 PF13385.6 EGB04895.1 - 3.5e-26 92.2 19.1 2.6e-15 56.9 0.1 5.9 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily REJ PF02010.15 EGB04895.1 - 2e-21 76.3 0.0 3e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 REJ domain AbfS_sensor PF18225.1 EGB04895.1 - 0.0011 18.8 0.0 40 4.2 0.0 6.4 9 0 0 9 9 9 1 Sensor histidine kinase (AbfS) sensor domain FAD_binding_3 PF01494.19 EGB04896.1 - 1.4e-11 44.2 0.1 1.2e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain WD40 PF00400.32 EGB04899.1 - 3.1e-16 59.5 3.2 0.011 16.6 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat VCH_CASS14 PF18315.1 EGB04899.1 - 0.095 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain ATP-grasp_4 PF13535.6 EGB04900.1 - 1.8e-21 76.4 0.0 3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 EGB04900.1 - 4.4e-09 36.2 0.0 7.9e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 EGB04900.1 - 1.5e-08 34.4 0.0 3.1e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EGB04900.1 - 3.9e-08 33.1 0.0 7e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGB04900.1 - 4.9e-08 33.2 0.0 1.2e-07 32.0 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 EGB04900.1 - 5.9e-07 30.0 3.0 1.4e-06 28.7 0.2 2.9 3 0 0 3 3 3 1 ATP-grasp N-terminal domain GARS_A PF01071.19 EGB04900.1 - 1.6e-06 28.0 0.0 0.0062 16.3 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 EGB04900.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.16 EGB04900.1 - 0.08 12.3 0.0 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_5 PF13549.6 EGB04900.1 - 0.1 12.0 0.1 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 EGB04900.1 - 0.23 10.7 0.0 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Myb_DNA-binding PF00249.31 EGB04901.1 - 3.6e-11 43.1 0.2 4.6e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB04901.1 - 3e-05 23.8 0.1 3.4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EGB04901.1 - 7e-05 23.0 0.0 8.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Scramblase PF03803.15 EGB04902.1 - 1.3e-17 63.9 0.1 2.8e-11 43.1 0.0 4.4 3 2 0 3 3 3 3 Scramblase Sec10 PF07393.11 EGB04903.1 - 5.6e-05 21.8 0.0 0.0044 15.5 0.0 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 Aa_trans PF01490.18 EGB04904.1 - 1.9e-59 201.4 1.3 2.5e-59 201.1 1.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_11 PF08241.12 EGB04905.1 - 1.9e-24 86.1 0.0 2.6e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB04905.1 - 8.1e-21 74.5 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB04905.1 - 6.3e-19 68.4 0.0 7.9e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB04905.1 - 8.4e-17 61.7 0.0 1.3e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB04905.1 - 4.8e-13 49.2 0.0 5.3e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB04905.1 - 7.4e-10 38.6 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EGB04905.1 - 9e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 EGB04905.1 - 0.00071 19.0 0.0 0.00091 18.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGB04905.1 - 0.0018 17.9 0.0 0.0023 17.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 EGB04905.1 - 0.0018 19.3 0.0 0.0025 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGB04905.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 EGB04905.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 2 0 0 2 2 2 0 Hypothetical methyltransferase AdoMet_MTase PF07757.13 EGB04905.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TPMT PF05724.11 EGB04905.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EGB04905.1 - 0.22 11.5 0.0 0.29 11.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Sigma70_ner PF04546.13 EGB04906.1 - 0.0085 16.0 3.1 0.0085 16.0 3.1 2.4 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF4972 PF16342.5 EGB04906.1 - 0.039 13.7 0.1 0.2 11.4 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) DnaB_bind PF10410.9 EGB04906.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.2 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase PPP4R2 PF09184.11 EGB04906.1 - 4.5 6.8 7.2 1.8 8.1 4.7 1.6 2 0 0 2 2 2 0 PPP4R2 Sulfatase PF00884.23 EGB04907.1 - 8.9e-25 87.7 0.0 9.8e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB04907.1 - 0.00041 20.0 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGB04907.1 - 0.022 13.4 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Acyl-CoA_dh_C PF12806.7 EGB04908.1 - 5.2e-29 100.9 10.6 1.3e-28 99.7 10.6 1.7 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 EGB04908.1 - 6.4e-18 65.4 1.8 6.4e-18 65.4 1.8 3.5 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGB04908.1 - 1.5e-13 50.7 0.0 4.6e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGB04908.1 - 7e-13 49.2 0.6 6.4e-12 46.1 0.0 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 EGB04908.1 - 0.00014 21.8 2.3 0.00033 20.6 2.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Ank_2 PF12796.7 EGB04909.1 - 3.6e-06 27.5 0.3 0.0031 18.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB04909.1 - 2.6e-05 24.4 2.0 0.26 11.7 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB04909.1 - 0.00021 21.8 0.1 0.052 14.1 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB04909.1 - 0.00024 21.3 0.2 11 6.9 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat Cupin_8 PF13621.6 EGB04909.1 - 0.001 18.8 0.0 2.2 7.9 0.0 3.2 2 1 0 2 2 2 1 Cupin-like domain Ank PF00023.30 EGB04909.1 - 0.0012 19.1 6.9 5.3 7.7 1.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat JmjC PF02373.22 EGB04909.1 - 0.031 14.7 0.0 0.13 12.7 0.0 1.9 1 1 1 2 2 2 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGB04909.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 EGB04909.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Cupin zf-nanos PF05741.13 EGB04910.1 - 0.0011 19.2 8.0 0.04 14.1 1.7 3.5 3 0 0 3 3 3 2 Nanos RNA binding domain LRR_4 PF12799.7 EGB04910.1 - 0.18 12.3 0.0 21 5.7 0.0 4.0 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) ChaC PF04752.12 EGB04911.1 - 1.7e-42 145.5 0.0 2.2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 EGB04911.1 - 2.2e-07 31.5 0.0 3.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Npun_R1517 PF18068.1 EGB04911.1 - 0.16 12.4 0.0 0.33 11.3 0.0 1.6 1 1 0 1 1 1 0 Npun R1517 Helicase_C PF00271.31 EGB04912.1 - 1.1e-15 57.9 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EGB04912.1 - 2.2e-06 27.9 0.1 4.7e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGB04913.1 - 7.4e-14 51.9 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Peptidase_M3 PF01432.20 EGB04914.1 - 1.9e-76 258.2 0.0 2.3e-76 257.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Aa_trans PF01490.18 EGB04914.1 - 1.1e-25 90.2 0.0 1.6e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-RING_2 PF13639.6 EGB04915.1 - 0.0068 16.7 6.2 0.0068 16.7 6.2 2.3 2 0 0 2 2 2 1 Ring finger domain PSCyt1 PF07635.11 EGB04915.1 - 0.019 15.5 1.2 4 8.1 0.1 3.2 2 0 0 2 2 2 0 Planctomycete cytochrome C zf-RING_5 PF14634.6 EGB04915.1 - 0.076 13.0 3.5 0.2 11.7 3.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Lactamase_B PF00753.27 EGB04915.1 - 0.42 10.6 4.2 31 4.5 4.0 3.3 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily zf-rbx1 PF12678.7 EGB04915.1 - 0.51 10.7 4.6 0.33 11.3 1.8 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGB04915.1 - 0.57 10.1 3.0 1.3 9.0 3.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB04915.1 - 0.83 9.6 7.1 2.2 8.2 7.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGB04915.1 - 5.4 7.2 6.1 1.3 9.1 2.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pkinase_Tyr PF07714.17 EGB04916.1 - 4.4e-50 170.4 0.0 6.4e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB04916.1 - 1e-41 143.0 0.0 1.7e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGB04916.1 - 0.00078 18.3 0.1 0.0028 16.5 0.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGB04916.1 - 0.0022 17.4 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB04916.1 - 0.004 16.5 0.1 0.18 11.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGB04916.1 - 0.043 13.7 0.3 1.6 8.6 0.3 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC_tran PF00005.27 EGB04917.1 - 3.1e-46 157.3 0.0 7.5e-24 84.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB04917.1 - 1.4e-21 77.6 0.0 3e-09 37.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGB04917.1 - 3e-15 56.2 26.5 1.8e-07 30.6 7.6 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_23 PF13476.6 EGB04917.1 - 7.8e-06 26.5 0.4 0.009 16.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain MukB PF04310.12 EGB04917.1 - 0.00024 21.0 1.2 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 MukB N-terminal AAA_29 PF13555.6 EGB04917.1 - 0.00037 20.2 0.1 0.19 11.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGB04917.1 - 0.0008 19.6 0.0 4.2 7.7 0.0 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EGB04917.1 - 0.0034 17.1 0.0 4.5 6.9 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain SRP54 PF00448.22 EGB04917.1 - 0.0053 16.4 0.6 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EGB04917.1 - 0.0086 15.8 0.5 3.7 7.2 0.3 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGB04917.1 - 0.16 11.6 0.1 15 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EGB04917.1 - 0.27 9.9 0.0 13 4.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Exostosin PF03016.15 EGB04918.1 - 2.5e-23 82.8 0.0 1.3e-22 80.4 0.0 2.1 2 1 0 2 2 2 1 Exostosin family Methyltransf_16 PF10294.9 EGB04919.1 - 7.7e-18 64.8 0.0 9.7e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGB04919.1 - 0.001 19.8 0.0 0.0014 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB04919.1 - 0.0021 17.9 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB04919.1 - 0.0098 16.6 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB04919.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GidB PF02527.15 EGB04919.1 - 0.029 13.7 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RNA_pol_I_A49 PF06870.12 EGB04920.1 - 2.4e-27 95.8 0.0 5.6e-27 94.6 0.0 1.5 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor HMG_box PF00505.19 EGB04920.1 - 6.3e-12 45.7 0.0 1.6e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box Dynamin_N PF00350.23 EGB04920.1 - 9.1e-10 38.8 0.0 3.5e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB04920.1 - 7.8e-06 26.0 0.0 7.5e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase LRR_6 PF13516.6 EGB04920.1 - 3.8e-05 23.4 1.0 0.021 14.8 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat RsgA_GTPase PF03193.16 EGB04920.1 - 0.0017 18.3 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase HMG_box_2 PF09011.10 EGB04920.1 - 0.0018 18.8 0.0 0.0041 17.7 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain ABC_tran PF00005.27 EGB04920.1 - 0.0087 16.6 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter LRR_4 PF12799.7 EGB04920.1 - 0.054 13.9 0.1 1.6 9.3 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) AIG1 PF04548.16 EGB04920.1 - 0.23 10.8 0.0 0.44 9.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family RNA_pol_Rpb2_6 PF00562.28 EGB04921.1 - 5.6e-124 414.2 0.0 7.6e-124 413.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGB04921.1 - 3.2e-53 180.3 0.0 4.6e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGB04921.1 - 2e-48 164.5 0.1 3.6e-48 163.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EGB04921.1 - 1.7e-26 92.2 0.0 4.3e-26 90.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EGB04921.1 - 3.6e-24 84.8 0.1 8.2e-24 83.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.20 EGB04921.1 - 7.1e-22 77.6 0.1 2.1e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 EGB04921.1 - 5.8e-17 62.0 1.0 1.3e-16 60.8 1.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 cNMP_binding PF00027.29 EGB04922.1 - 1.1e-57 192.1 0.4 4.1e-20 71.7 0.0 4.1 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain WD40 PF00400.32 EGB04922.1 - 4e-12 46.4 7.1 0.0016 19.2 0.2 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.25 EGB04922.1 - 9.4e-10 38.3 0.2 9.8e-08 31.7 0.1 2.4 1 1 1 2 2 2 1 Protein kinase domain HEAT_EZ PF13513.6 EGB04922.1 - 2.3e-07 31.2 2.6 7.7e-07 29.5 0.2 3.0 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 EGB04922.1 - 2.5e-06 27.8 0.7 0.00082 19.7 0.0 2.8 1 1 0 2 2 2 1 HEAT repeats ANAPC4_WD40 PF12894.7 EGB04922.1 - 3.1e-06 27.4 0.1 3.8 7.9 0.0 4.9 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.22 EGB04922.1 - 2.1e-05 24.4 0.2 0.11 12.8 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 EGB04922.1 - 0.00011 22.1 4.1 0.11 12.6 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGB04922.1 - 0.0057 15.3 0.1 0.011 14.3 0.1 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Pkinase_Tyr PF07714.17 EGB04922.1 - 0.0061 15.9 0.1 0.015 14.6 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Gp_dh_C PF02800.20 EGB04923.1 - 6e-67 224.2 0.0 9.1e-67 223.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGB04923.1 - 1.7e-34 118.2 1.1 4.1e-33 113.7 1.1 2.4 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EGB04923.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EGB04923.1 - 0.099 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UVR PF02151.19 EGB04924.1 - 0.0002 21.0 11.9 0.023 14.4 0.8 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif XRCC1_N PF01834.16 EGB04924.1 - 0.024 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain HEAT PF02985.22 EGB04924.1 - 0.26 11.6 1.7 7.2 7.2 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat Vac14_Fig4_bd PF11916.8 EGB04925.1 - 4.3e-71 238.3 9.2 1.6e-70 236.4 7.9 2.3 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EGB04925.1 - 2.8e-49 165.7 0.2 2.9e-41 140.0 0.0 4.4 3 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGB04925.1 - 5.2e-19 66.7 1.6 8.3e-05 22.5 0.0 8.1 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.6 EGB04925.1 - 2.4e-12 47.1 0.3 0.0018 18.7 0.0 5.1 4 0 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 EGB04925.1 - 7.1e-09 35.9 1.1 0.29 11.6 0.0 6.2 5 2 0 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EGB04925.1 - 1.2e-08 35.1 1.2 0.031 14.3 0.0 4.9 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGB04925.1 - 1.7e-06 27.7 0.0 0.0023 17.5 0.0 4.3 2 2 2 4 4 4 1 CLASP N terminal IFRD PF05004.13 EGB04925.1 - 0.00038 19.6 0.2 2.2 7.3 0.0 3.7 2 1 2 4 4 4 2 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 EGB04925.1 - 0.00046 19.4 6.3 1.3 8.1 0.3 4.0 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 EGB04925.1 - 0.00081 19.5 1.1 0.082 13.1 0.2 3.6 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 EGB04925.1 - 0.0043 16.6 1.6 0.087 12.3 0.0 3.2 3 0 0 3 3 3 1 Tti2 family Arm PF00514.23 EGB04925.1 - 0.0086 16.1 0.8 6.2 7.0 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat ParcG PF10274.9 EGB04925.1 - 0.011 15.9 4.0 0.32 11.1 0.2 3.6 2 1 2 4 4 4 0 Parkin co-regulated protein Ras PF00071.22 EGB04926.1 - 4e-09 36.3 0.0 5.3e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Ras family PRKCSH-like PF12999.7 EGB04926.1 - 3.2 7.5 8.3 0.081 12.7 1.5 1.7 2 0 0 2 2 2 0 Glucosidase II beta subunit-like Pkinase PF00069.25 EGB04927.1 - 3.8e-64 216.6 0.0 4.5e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04927.1 - 4.7e-38 130.9 0.0 5.8e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04927.1 - 3.1e-05 23.4 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB04927.1 - 0.00017 21.0 1.7 0.0006 19.2 1.8 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB04927.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB04927.1 - 0.09 11.7 0.2 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain HTH_39 PF14090.6 EGB04927.1 - 0.56 10.0 2.6 2.6 7.8 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain CLP_protease PF00574.23 EGB04929.1 - 2.1e-78 262.4 0.0 2.6e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease DEK_C PF08766.11 EGB04930.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 DEK C terminal domain UvrA_DNA-bind PF17755.1 EGB04930.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 UvrA DNA-binding domain INCENP_ARK-bind PF03941.15 EGB04931.1 - 6.2e-14 51.7 0.3 1.6e-13 50.4 0.1 1.8 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region SAP PF02037.27 EGB04931.1 - 1.5e-08 34.2 1.2 3.7e-08 32.9 1.2 1.7 1 0 0 1 1 1 1 SAP domain APC1_C PF18122.1 EGB04934.1 - 2.5e-20 73.1 0.0 4.8e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 EGB04934.1 - 0.00092 19.5 25.2 0.015 15.7 0.4 6.1 6 0 0 6 6 6 3 Proteasome/cyclosome repeat ICA69 PF04629.14 EGB04935.1 - 0.033 14.5 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain HEPN_Apea PF18739.1 EGB04935.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Apea-like HEPN TPR_2 PF07719.17 EGB04938.1 - 6.3e-15 54.0 45.8 0.005 16.9 0.1 12.3 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGB04938.1 - 4.5e-12 46.3 29.3 0.0033 17.9 1.2 7.9 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGB04938.1 - 2.7e-08 34.3 62.5 1.1e-05 26.0 1.4 9.5 10 1 2 12 12 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04938.1 - 1.2e-07 31.2 28.9 0.019 14.8 0.1 9.1 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB04938.1 - 3.2e-07 30.0 6.0 3.4 8.1 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB04938.1 - 3.9e-07 30.3 40.5 0.003 17.8 1.6 9.4 8 3 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB04938.1 - 9e-05 23.0 54.3 0.0017 19.0 2.0 10.8 10 3 3 13 13 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGB04938.1 - 0.00022 21.4 10.1 0.072 13.5 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB04938.1 - 0.00035 20.7 24.8 0.0019 18.4 0.1 5.8 6 1 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGB04938.1 - 0.00089 19.0 21.2 1.4 8.9 0.9 8.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB04938.1 - 0.0032 18.0 23.5 0.69 10.7 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGB04938.1 - 0.0054 17.2 0.8 0.0054 17.2 0.8 8.0 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGB04938.1 - 0.036 14.2 25.3 0.031 14.4 2.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB04938.1 - 0.092 12.8 11.9 13 6.1 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB04938.1 - 0.2 11.4 10.9 2.7 7.8 0.0 6.6 7 1 1 8 8 8 0 TPR repeat Adaptin_N PF01602.20 EGB04939.1 - 3.4e-83 280.0 5.2 5.2e-83 279.4 5.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EGB04939.1 - 1.6e-49 167.4 0.0 2.9e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EGB04939.1 - 4.7e-17 62.2 0.3 1e-16 61.1 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EGB04939.1 - 3.2e-09 37.0 2.1 5.3e-08 33.1 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGB04939.1 - 3.3e-08 33.8 1.8 0.0048 17.3 0.0 4.6 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EGB04939.1 - 3.5e-07 29.9 0.5 0.015 15.5 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EGB04939.1 - 0.00065 20.1 0.5 5.3 7.6 0.0 4.5 4 0 0 4 4 3 1 HEAT-like repeat Arm PF00514.23 EGB04939.1 - 0.0028 17.6 3.1 0.95 9.6 0.4 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat ParcG PF10274.9 EGB04939.1 - 0.017 15.3 1.3 0.48 10.5 0.0 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein Alpha_adaptinC2 PF02883.20 EGB04939.1 - 0.057 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Adaptin C-terminal domain DUF484 PF04340.12 EGB04939.1 - 0.075 12.7 1.1 0.2 11.3 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF484 TPR_2 PF07719.17 EGB04940.1 - 3.2e-09 36.2 3.1 0.0074 16.3 0.0 3.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB04940.1 - 1.7e-05 25.4 11.4 0.00039 21.0 0.7 3.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04940.1 - 9.5e-05 22.1 3.1 0.17 11.7 0.0 3.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB04940.1 - 0.013 16.3 4.1 0.33 11.9 0.0 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB04940.1 - 0.027 15.1 5.5 2.3 9.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 EGB04940.1 - 0.07 12.6 0.2 0.78 9.2 0.1 2.1 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 EGB04940.1 - 0.1 12.9 5.7 3.9 7.8 0.9 3.4 2 2 0 2 2 2 0 Tetratricopeptide repeat PGM_PMM_I PF02878.16 EGB04940.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I MFS_1 PF07690.16 EGB04941.1 - 9.9e-42 143.1 35.7 2.2e-23 82.8 14.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB04941.1 - 1.1e-12 47.6 12.4 1.8e-06 27.1 1.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Glycos_transf_1 PF00534.20 EGB04941.1 - 9.8e-09 35.0 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 EGB04941.1 - 1.2e-07 31.7 0.0 2.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB04941.1 - 2.5e-06 27.5 0.0 1.5e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PAN_1 PF00024.26 EGB04941.1 - 9.5e-06 25.5 2.9 2.4e-05 24.2 2.9 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 EGB04941.1 - 0.0001 22.1 1.8 0.00022 21.1 1.8 1.5 1 0 0 1 1 1 1 PAN domain MFS_1_like PF12832.7 EGB04941.1 - 0.024 13.5 0.2 0.83 8.4 0.0 2.3 2 0 0 2 2 2 0 MFS_1 like family PAN_2 PF08276.11 EGB04941.1 - 0.077 13.1 2.1 0.2 11.8 2.1 1.6 1 0 0 1 1 1 0 PAN-like domain Glyco_transf_18 PF15024.6 EGB04941.1 - 0.24 10.0 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 TRI12 PF06609.13 EGB04941.1 - 3.6 5.9 10.4 0.3 9.4 2.4 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) WW PF00397.26 EGB04942.1 - 1.5e-07 31.3 19.3 0.0032 17.5 4.1 3.4 3 0 0 3 3 3 3 WW domain TPR_10 PF13374.6 EGB04943.1 - 1.1e-54 180.9 23.1 4.3e-11 42.3 0.0 6.5 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGB04943.1 - 6.3e-51 170.6 26.8 4.6e-14 52.5 1.3 5.9 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGB04943.1 - 7e-18 63.3 16.9 2.5e-06 27.1 0.3 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB04943.1 - 3.6e-16 58.0 11.6 0.00041 20.4 0.2 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04943.1 - 2.3e-10 39.9 17.5 0.00012 21.8 0.3 6.2 6 2 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGB04943.1 - 7.6e-10 38.1 18.6 0.00022 21.1 0.3 6.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_5 PF12688.7 EGB04943.1 - 3.3e-06 27.3 5.1 1.1 9.6 0.1 4.5 1 1 3 4 4 4 2 Tetratrico peptide repeat TPR_6 PF13174.6 EGB04943.1 - 0.00023 21.6 6.5 4.7 8.1 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB04943.1 - 0.00037 20.7 6.0 20 5.9 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF1955 PF09205.10 EGB04943.1 - 0.0013 18.5 1.2 14 5.4 0.0 4.2 1 1 4 5 5 5 0 Domain of unknown function (DUF1955) DUF2225 PF09986.9 EGB04943.1 - 0.0019 17.9 0.0 8.2 6.1 0.0 3.3 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Lambda_tail_I PF06805.12 EGB04943.1 - 0.0027 18.0 1.1 32 5.0 0.0 4.6 5 0 0 5 5 5 0 Bacteriophage lambda tail assembly protein I TPR_14 PF13428.6 EGB04943.1 - 0.0058 17.4 13.4 0.47 11.4 0.2 5.4 4 1 2 6 6 6 1 Tetratricopeptide repeat Mob_Pre PF01076.19 EGB04943.1 - 0.018 14.9 0.0 9.5 6.0 0.0 3.5 2 2 0 3 3 3 0 Plasmid recombination enzyme TPR_11 PF13414.6 EGB04943.1 - 0.049 13.3 12.2 0.54 10.0 0.5 4.8 5 0 0 5 5 5 0 TPR repeat DUF5471 PF17565.2 EGB04943.1 - 0.053 13.8 5.6 11 6.4 0.0 4.6 2 1 2 5 5 5 0 Family of unknown function (DUF5471) DUF1501 PF07394.12 EGB04943.1 - 0.089 11.8 0.3 4.6 6.2 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1501) TPR_4 PF07721.14 EGB04943.1 - 0.12 13.1 11.6 5.1 8.0 0.0 6.0 7 1 0 7 7 5 0 Tetratricopeptide repeat Trp_repressor PF01371.19 EGB04943.1 - 0.14 12.3 0.2 24 5.1 0.0 3.7 2 1 3 5 5 5 0 Trp repressor protein TPR_16 PF13432.6 EGB04943.1 - 8.4 7.1 14.2 1.2 9.8 0.6 4.1 2 2 3 5 5 5 0 Tetratricopeptide repeat DnaJ PF00226.31 EGB04944.1 - 3.6e-17 62.3 0.2 7.1e-17 61.3 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain PDZ_6 PF17820.1 EGB04944.1 - 0.0045 16.8 0.2 0.013 15.4 0.2 1.8 1 0 0 1 1 1 1 PDZ domain Nkap_C PF06047.11 EGB04944.1 - 0.089 12.9 0.3 0.089 12.9 0.3 2.2 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain PDZ PF00595.24 EGB04944.1 - 0.15 12.4 0.3 0.36 11.2 0.1 1.7 2 0 0 2 2 2 0 PDZ domain PH_6 PF15406.6 EGB04944.1 - 0.27 11.5 0.0 0.27 11.5 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain DUF525 PF04379.14 EGB04945.1 - 2.5e-22 78.9 0.1 3e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 ApaG domain ArfGap PF01412.18 EGB04946.1 - 1.2e-31 109.2 0.0 1.3e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 EGB04946.1 - 0.1 12.6 0.3 2.8 8.0 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger WW PF00397.26 EGB04947.1 - 1.1e-24 86.1 14.9 3.7e-12 46.1 3.6 2.1 2 0 0 2 2 2 2 WW domain Lpp-LpqN PF10738.9 EGB04947.1 - 0.97 8.9 4.4 7 6.1 0.4 2.1 1 1 1 2 2 2 0 Probable lipoprotein LpqN Peptidase_C14 PF00656.22 EGB04948.1 - 1.9e-49 168.9 0.0 4.8e-49 167.6 0.0 1.5 1 1 0 1 1 1 1 Caspase domain DUF3082 PF11282.8 EGB04949.1 - 6.8e-17 61.5 2.9 6.8e-17 61.5 2.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3082) Beta_helix PF13229.6 EGB04949.1 - 4.3e-13 49.4 0.1 0.00014 21.8 0.1 3.9 1 1 2 3 3 3 3 Right handed beta helix region DUF488 PF04343.13 EGB04949.1 - 1.7e-06 28.6 2.0 0.00056 20.5 2.0 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF488 TRP PF06011.12 EGB04949.1 - 0.58 8.8 7.1 0.025 13.3 0.7 1.8 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Ephrin_rec_like PF07699.13 EGB04949.1 - 9.7 6.1 12.2 0.97 9.3 4.9 2.7 2 1 0 2 2 2 0 Putative ephrin-receptor like Spermine_synth PF01564.17 EGB04950.1 - 6.2e-39 133.4 0.0 8.3e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGB04950.1 - 6.6e-13 48.3 0.1 2e-12 46.8 0.0 1.9 1 1 1 2 2 2 1 Spermidine synthase tetramerisation domain Methyltransf_30 PF05430.11 EGB04950.1 - 7.7e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 EGB04950.1 - 0.0011 19.6 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FerA PF08165.11 EGB04950.1 - 0.0029 17.5 0.1 0.0083 16.1 0.0 1.7 2 0 0 2 2 2 1 FerA (NUC095) domain Methyltransf_24 PF13578.6 EGB04950.1 - 0.02 15.9 0.0 0.064 14.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB04950.1 - 0.12 13.1 0.0 0.32 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Dynamin_N PF00350.23 EGB04951.1 - 8.6e-11 42.2 0.0 3.2e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Dynamin family DUF5600 PF18150.1 EGB04951.1 - 1e-10 42.2 0.1 1.9e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) MMR_HSR1 PF01926.23 EGB04951.1 - 9.7e-08 32.1 0.0 3.5e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGB04951.1 - 0.0028 17.9 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EGB04951.1 - 0.003 17.1 0.1 0.31 10.5 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGB04951.1 - 0.016 15.2 0.6 3.5 7.5 0.0 2.7 4 0 0 4 4 4 0 RsgA GTPase Rieske PF00355.26 EGB04952.1 - 5.8e-19 67.8 0.0 1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 EGB04952.1 - 1.3e-11 44.4 0.0 2.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske_2 PF13806.6 EGB04952.1 - 0.009 15.9 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Na_H_Exchanger PF00999.21 EGB04954.1 - 5.1e-45 153.9 33.2 7.3e-45 153.4 33.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EGB04954.1 - 3.3e-16 59.6 0.1 7.1e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain EF-hand_7 PF13499.6 EGB04954.1 - 2.2e-08 34.4 0.0 4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB04954.1 - 4.3e-05 22.8 0.0 0.0001 21.6 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EGB04954.1 - 6.9e-05 22.1 0.0 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB04954.1 - 0.00039 20.1 0.0 0.00094 18.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_9 PF14658.6 EGB04954.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain HTH_AsnC-type PF13404.6 EGB04954.1 - 2.7 7.9 5.6 10 6.0 0.1 3.6 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain TPH PF13868.6 EGB04955.1 - 1.6e-08 33.5 69.3 1.6e-08 33.5 69.3 5.8 4 2 2 6 6 6 1 Trichohyalin-plectin-homology domain Kelch_1 PF01344.25 EGB04955.1 - 1.7e-08 33.9 3.5 0.0012 18.4 0.0 4.2 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EGB04955.1 - 9e-08 32.1 0.0 0.84 10.0 0.0 4.8 5 0 0 5 5 5 3 Kelch motif zf-C2H2 PF00096.26 EGB04955.1 - 0.12 12.9 0.4 0.33 11.5 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGB04955.1 - 0.14 13.1 0.4 0.45 11.5 0.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Kelch_4 PF13418.6 EGB04955.1 - 0.16 12.0 0.6 4.5 7.4 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain ILVD_EDD PF00920.21 EGB04956.1 - 1.8e-201 670.3 0.6 2.1e-201 670.0 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family HeH PF12949.7 EGB04956.1 - 0.0026 17.4 0.2 0.0047 16.6 0.2 1.3 1 0 0 1 1 1 1 HeH/LEM domain Laminin_G_3 PF13385.6 EGB04957.1 - 1.9e-44 151.4 5.8 9.3e-22 77.8 2.5 4.0 4 0 0 4 4 4 3 Concanavalin A-like lectin/glucanases superfamily REJ PF02010.15 EGB04957.1 - 2e-24 86.2 0.0 2.6e-23 82.6 0.0 2.3 2 1 0 2 2 2 1 REJ domain PT PF04886.12 EGB04957.1 - 4.2e-12 45.4 252.9 0.0038 16.7 20.3 11.7 5 4 5 11 11 11 10 PT repeat Pentaxin PF00354.17 EGB04957.1 - 6.5e-08 32.5 0.0 0.00062 19.5 0.0 3.1 3 0 0 3 3 3 2 Pentaxin family TPR_11 PF13414.6 EGB04957.1 - 0.03 14.0 0.4 0.14 11.9 0.5 2.1 2 0 0 2 2 2 0 TPR repeat Laminin_G_2 PF02210.24 EGB04957.1 - 0.066 13.8 0.1 0.54 10.8 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain TPR_2 PF07719.17 EGB04957.1 - 0.083 13.0 10.6 1.5 9.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TUDOR_5 PF18359.1 EGB04957.1 - 0.11 12.2 0.2 0.4 10.4 0.2 2.0 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 TPR_1 PF00515.28 EGB04957.1 - 2.1 8.3 5.4 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TTL PF03133.15 EGB04958.1 - 1.7e-70 237.5 0.0 2.2e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB04958.1 - 0.0036 16.6 0.0 0.0081 15.4 0.0 1.6 2 0 0 2 2 2 1 YheC/D like ATP-grasp MnmE_helical PF12631.7 EGB04959.1 - 3e-40 138.6 0.4 3.9e-40 138.2 0.4 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EGB04959.1 - 1.3e-34 119.0 0.0 4.3e-34 117.3 0.0 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EGB04959.1 - 7.4e-11 42.1 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GCV_T PF01571.21 EGB04959.1 - 0.045 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain eIF-4B PF06273.11 EGB04960.1 - 2e-11 43.6 6.8 4e-11 42.7 6.7 1.5 1 1 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B DUF4686 PF15742.5 EGB04960.1 - 0.039 13.1 6.3 0.045 12.9 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Pantoate_ligase PF02569.15 EGB04960.1 - 0.051 12.8 1.6 0.065 12.4 1.6 1.1 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Apo-CIII PF05778.12 EGB04960.1 - 0.072 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Pilosulin PF17499.2 EGB04960.1 - 0.089 13.0 3.1 1.7 8.9 0.6 2.2 2 0 0 2 2 2 0 Ant venom peptides OmpH PF03938.14 EGB04960.1 - 0.12 12.7 7.5 0.16 12.3 7.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4192 PF13830.6 EGB04960.1 - 0.42 10.6 9.7 0.52 10.3 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Erythro_esteras PF05139.14 EGB04960.1 - 0.42 10.4 7.7 0.46 10.2 7.7 1.0 1 0 0 1 1 1 0 Erythromycin esterase V_ATPase_I PF01496.19 EGB04960.1 - 0.68 7.8 4.0 0.78 7.6 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L12 PF00542.19 EGB04961.1 - 1.2e-28 99.3 9.4 1.3e-27 96.0 6.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGB04961.1 - 1.2e-17 63.3 5.8 1.2e-17 63.3 5.8 2.8 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DAHP_snth_FXD PF18152.1 EGB04961.1 - 0.13 12.2 1.8 0.26 11.1 0.2 2.3 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain Aldedh PF00171.22 EGB04962.1 - 1.3e-137 459.2 0.0 1.6e-137 458.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TetR_C_6 PF13977.6 EGB04962.1 - 7.3 6.9 18.2 6.1 7.1 4.4 4.2 3 1 1 4 4 4 0 BetI-type transcriptional repressor, C-terminal LSM PF01423.22 EGB04963.1 - 4.9e-16 58.2 0.1 5.9e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SWIRM-assoc_2 PF16496.5 EGB04964.1 - 9.4e-07 28.0 2.9 0.00042 19.3 0.5 2.9 3 0 0 3 3 3 2 SWIRM-associated domain at the N-terminal CAP_GLY PF01302.25 EGB04966.1 - 5.1e-23 80.9 0.5 5.4e-23 80.8 0.5 1.0 1 0 0 1 1 1 1 CAP-Gly domain Cpn60_TCP1 PF00118.24 EGB04968.1 - 5.6e-152 506.8 13.6 6.5e-152 506.6 13.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DEAD PF00270.29 EGB04969.1 - 2.7e-41 141.2 0.0 3.2e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB04969.1 - 0.0001 22.3 0.0 0.00012 22.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGB04969.1 - 0.00016 22.0 0.0 0.00033 20.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EGB04969.1 - 0.067 13.0 0.0 0.095 12.5 0.0 1.4 1 1 0 1 1 1 0 Helicase Sulfatase PF00884.23 EGB04970.1 - 6.7e-38 130.8 0.1 9e-38 130.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Pkinase PF00069.25 EGB04970.1 - 5.1e-32 111.3 0.0 9.3e-32 110.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04970.1 - 6.3e-13 48.6 0.0 9.2e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase His_Phos_1 PF00300.22 EGB04971.1 - 1.6e-37 129.1 0.0 2.3e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Coprogen_oxidas PF01218.18 EGB04972.1 - 3.9e-51 173.5 0.0 1.8e-35 122.1 0.0 2.0 2 0 0 2 2 2 2 Coproporphyrinogen III oxidase Tli4_C PF18426.1 EGB04973.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 1 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain Pyr_redox_2 PF07992.14 EGB04974.1 - 5.5e-22 78.4 0.0 9.3e-22 77.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB04974.1 - 1.9e-06 28.4 0.8 0.042 14.4 1.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB04974.1 - 8.8e-05 22.7 5.9 0.0064 16.7 0.1 3.3 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB04974.1 - 0.00071 19.3 15.5 0.0016 18.1 0.2 3.9 2 2 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB04974.1 - 0.00098 18.3 3.7 0.005 16.0 0.0 2.6 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EGB04974.1 - 0.007 15.5 3.0 0.16 10.9 0.0 2.9 2 1 1 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGB04974.1 - 0.054 12.8 0.2 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGB04974.1 - 0.088 11.9 1.6 3.1 6.8 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EGB04974.1 - 0.089 12.8 4.7 4.8 7.1 0.1 3.3 2 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EGB04974.1 - 0.11 11.2 0.1 0.31 9.7 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EGB04974.1 - 0.14 11.4 0.0 0.7 9.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 EGB04974.1 - 0.17 11.0 0.0 26 3.8 0.1 2.6 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EGB04974.1 - 0.38 10.0 9.1 0.77 8.9 0.7 3.0 4 0 0 4 4 4 0 FAD binding domain Amnionless PF14828.6 EGB04975.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless EBV-NA1 PF02905.14 EGB04975.1 - 0.051 13.4 0.2 0.051 13.4 0.2 2.3 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Zn_peptidase PF04228.13 EGB04975.1 - 0.058 12.8 1.5 0.43 10.0 0.1 2.1 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase DUF4577 PF15145.6 EGB04975.1 - 0.22 11.6 0.0 0.37 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) YHYH PF14240.6 EGB04975.1 - 1.6 8.6 10.5 0.082 12.9 2.0 2.5 1 1 1 2 2 2 0 YHYH protein Pro_isomerase PF00160.21 EGB04976.1 - 1e-37 129.8 0.0 1.2e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Snf7 PF03357.21 EGB04977.1 - 8.4e-42 142.7 13.5 1.1e-41 142.3 13.5 1.1 1 0 0 1 1 1 1 Snf7 Ax_dynein_light PF10211.9 EGB04977.1 - 0.0059 16.6 0.9 0.0059 16.6 0.9 2.2 1 1 1 2 2 2 1 Axonemal dynein light chain Cwf_Cwc_15 PF04889.12 EGB04977.1 - 0.44 10.2 7.6 0.74 9.5 7.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein E2F_CC-MB PF16421.5 EGB04977.1 - 4.2 7.8 8.7 0.93 9.9 2.0 2.4 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain Methyltransf_25 PF13649.6 EGB04978.1 - 5.8e-07 30.1 0.0 2.6e-06 28.1 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB04978.1 - 7.4e-06 25.9 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB04978.1 - 5.8e-05 23.8 0.0 0.00011 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB04978.1 - 0.00026 21.6 0.0 0.00064 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain LRR_8 PF13855.6 EGB04979.1 - 2.4e-42 142.5 29.8 8.5e-10 38.3 0.7 8.2 3 1 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 EGB04979.1 - 2.5e-35 119.9 9.9 0.00031 21.1 0.2 9.5 7 1 3 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB04979.1 - 4.8e-13 47.7 5.1 3.7 8.5 0.1 10.7 12 0 0 12 12 12 1 Leucine Rich Repeat LRR_9 PF14580.6 EGB04979.1 - 4.7e-09 36.0 7.5 0.015 14.8 0.1 5.4 2 2 3 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 EGB04979.1 - 5.8e-09 35.3 15.7 4.2 7.7 0.1 9.0 9 0 0 9 9 9 3 Leucine Rich repeat TPR_2 PF07719.17 EGB04979.1 - 0.00079 19.4 4.5 0.014 15.5 1.6 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB04979.1 - 0.024 14.5 2.9 0.075 12.9 1.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RsmF_methylt_CI PF17126.5 EGB04979.1 - 0.042 13.9 2.9 4.8 7.3 0.0 5.0 6 0 0 6 6 6 0 RsmF rRNA methyltransferase first C-terminal domain RRM_1 PF00076.22 EGB04980.1 - 5.4e-21 74.2 0.0 6.6e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGB04980.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ubiquitin PF00240.23 EGB04982.1 - 3.1e-35 119.7 0.5 3.4e-35 119.6 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB04982.1 - 3.9e-17 61.9 0.8 4.3e-17 61.7 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB04982.1 - 1e-06 29.1 0.1 4.1e-06 27.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB04982.1 - 0.00056 19.8 0.0 0.00063 19.6 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB04982.1 - 0.00091 19.3 0.1 0.0021 18.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGB04982.1 - 0.0018 18.6 0.0 0.0021 18.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGB04982.1 - 0.0031 17.5 0.2 2.4 8.3 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 EGB04982.1 - 0.0083 16.7 0.1 0.0091 16.5 0.1 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGB04982.1 - 0.091 12.6 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Ribosomal_S30 PF04758.14 EGB04983.1 - 6.4e-31 106.3 6.3 7e-31 106.2 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pkinase PF00069.25 EGB04984.1 - 1.7e-78 263.6 0.0 1.9e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB04984.1 - 4.8e-39 134.2 0.0 5.5e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB04984.1 - 5.5e-07 29.2 0.0 1e-06 28.3 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB04984.1 - 5.2e-05 22.2 0.0 7.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB04984.1 - 0.00064 19.1 0.1 0.00092 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB04984.1 - 0.013 15.5 0.2 0.065 13.1 0.4 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DnaJ PF00226.31 EGB04985.1 - 4.5e-16 58.7 0.3 1.2e-15 57.3 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain EF-hand_6 PF13405.6 EGB04986.1 - 4.2e-12 45.0 11.5 0.00039 20.1 2.2 3.4 3 1 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGB04986.1 - 6.5e-11 41.0 9.9 0.00042 19.7 0.6 3.5 3 1 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGB04986.1 - 2e-10 40.9 7.4 2.2e-07 31.2 4.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB04986.1 - 0.00016 21.0 15.1 0.028 13.9 1.6 4.0 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGB04986.1 - 0.0026 17.6 7.9 0.11 12.4 1.3 3.3 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 EGB04986.1 - 0.07 13.1 7.4 0.12 12.3 1.6 3.0 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGB04986.1 - 0.31 11.3 5.7 1.1 9.4 0.1 2.9 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_1 PF00036.32 EGB04987.1 - 1.1e-27 93.4 19.7 2.3e-07 29.9 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB04987.1 - 5.5e-25 85.1 13.2 1.6e-05 24.5 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGB04987.1 - 9.4e-19 67.6 13.6 9.1e-10 38.9 1.6 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB04987.1 - 1e-17 62.7 18.3 2.6e-06 26.7 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB04987.1 - 6.6e-14 51.5 18.3 0.00012 21.9 0.1 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EGB04987.1 - 1.1e-06 28.9 0.8 0.0013 19.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 EGB04987.1 - 2.2e-05 24.2 9.7 0.00068 19.4 0.8 2.9 2 2 1 3 3 3 2 EF hand EF-hand_4 PF12763.7 EGB04987.1 - 0.00024 21.0 7.0 0.064 13.2 0.2 3.2 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EGB04987.1 - 0.11 12.5 4.0 8.4 6.3 0.1 3.2 2 2 1 3 3 3 0 Caleosin related protein HTH_Tnp_4 PF13613.6 EGB04987.1 - 0.14 11.9 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease p25-alpha PF05517.12 EGB04987.1 - 0.15 12.2 1.9 9.1 6.4 0.1 3.0 2 2 0 2 2 2 0 p25-alpha SPARC_Ca_bdg PF10591.9 EGB04987.1 - 0.2 12.0 4.5 0.36 11.2 0.6 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF5640 PF18692.1 EGB04987.1 - 0.59 10.2 5.1 14 5.7 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5640) GatB_N PF02934.15 EGB04988.1 - 2.4e-86 289.5 0.0 3.1e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGB04988.1 - 6.7e-23 81.2 0.0 1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 GatB domain DUF2218 PF09981.9 EGB04988.1 - 0.16 12.4 1.1 0.34 11.3 0.1 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) AA_kinase PF00696.28 EGB04989.1 - 7.4e-35 120.7 0.2 1.2e-34 120.0 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 EGB04989.1 - 2.8e-06 26.1 10.2 0.00043 18.9 8.4 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family SAM_1 PF00536.30 EGB04991.1 - 0.03 14.8 0.1 0.051 14.0 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Helicase_C PF00271.31 EGB04992.1 - 0.00035 20.9 0.0 0.00049 20.4 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ATP-synt_ab PF00006.25 EGB04993.1 - 3.9e-71 239.1 0.1 5.3e-71 238.6 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGB04993.1 - 8e-46 155.5 0.0 1.1e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGB04993.1 - 5.8e-14 52.4 1.0 1.7e-13 50.9 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 EGB04993.1 - 0.014 14.7 0.4 0.055 12.8 0.2 2.0 2 0 0 2 2 2 0 KaiC Epimerase PF01370.21 EGB04994.1 - 1.1e-48 165.9 0.2 1.3e-48 165.6 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB04994.1 - 4.9e-48 164.2 0.1 1.3e-47 162.8 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGB04994.1 - 1.1e-16 60.9 0.0 1.6e-15 57.1 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGB04994.1 - 1.2e-11 44.2 0.0 1.8e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EGB04994.1 - 5.1e-09 35.5 0.0 6.6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGB04994.1 - 1.9e-05 24.0 0.3 0.006 15.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 EGB04994.1 - 0.068 13.1 0.4 0.18 11.7 0.2 1.9 2 1 0 2 2 2 0 KR domain Ribosomal_S20p PF01649.18 EGB04995.1 - 3.3e-24 85.3 10.4 3.9e-24 85.1 10.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S20 DnaJ PF00226.31 EGB04997.1 - 4.6e-25 87.5 0.0 8.1e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 EGB04997.1 - 2.2e-18 66.4 1.8 3.7e-18 65.7 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) RPT PF13446.6 EGB04997.1 - 0.093 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein TPR_1 PF00515.28 EGB04997.1 - 0.096 12.6 0.4 0.39 10.6 0.4 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat Arf PF00025.21 EGB04999.1 - 1.1e-39 135.7 0.0 1.5e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGB04999.1 - 6.2e-08 32.9 0.0 1e-07 32.2 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGB04999.1 - 1.7e-07 30.8 0.0 7.2e-05 22.1 0.0 2.4 2 1 0 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGB04999.1 - 8.3e-07 28.7 0.0 1.3e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGB04999.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB04999.1 - 0.00026 21.4 1.0 0.00072 20.0 1.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 EGB04999.1 - 0.0046 16.4 0.0 0.007 15.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGB04999.1 - 0.0058 16.0 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 EGB04999.1 - 0.014 15.0 0.0 4.2 6.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGB04999.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGB04999.1 - 0.044 13.8 0.0 0.077 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGB04999.1 - 0.071 13.7 0.0 0.14 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EGB04999.1 - 0.14 11.7 0.0 1.7 8.1 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EGB04999.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain LMWPc PF01451.21 EGB05000.1 - 6.3e-17 62.3 0.0 7.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Cytomega_UL20A PF05984.12 EGB05000.1 - 0.023 15.0 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein PT PF04886.12 EGB05001.1 - 2e-07 30.4 100.8 0.00069 19.1 11.2 6.8 1 1 1 2 2 2 1 PT repeat Voltage_CLC PF00654.20 EGB05002.1 - 6.4e-74 249.3 25.2 6.4e-74 249.3 25.2 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGB05002.1 - 1.4e-14 54.2 0.0 4.6e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.25 EGB05003.1 - 2e-25 89.7 0.0 3.8e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05003.1 - 6.6e-16 58.4 0.0 1.2e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB05003.1 - 1.6e-09 37.1 0.1 2.3e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB05003.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 EGB05003.1 - 0.0036 17.5 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 ABC1 family Pox_ser-thr_kin PF05445.11 EGB05003.1 - 0.067 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CH PF00307.31 EGB05004.1 - 1.5e-09 38.0 0.1 1.8e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGB05004.1 - 0.012 15.4 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Ser_hydrolase PF06821.13 EGB05005.1 - 8.4e-06 25.7 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 EGB05005.1 - 0.0058 15.9 0.0 0.034 13.4 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 NTP_transf_3 PF12804.7 EGB05006.1 - 5.4e-06 26.8 0.3 2e-05 25.0 0.1 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain EamA PF00892.20 EGB05006.1 - 0.0015 18.7 23.6 0.0044 17.2 5.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family NTP_transferase PF00483.23 EGB05006.1 - 0.046 13.3 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase TPR_12 PF13424.6 EGB05007.1 - 2.4e-157 511.6 104.5 1.9e-21 76.2 2.7 11.0 2 1 11 13 13 13 13 Tetratricopeptide repeat TPR_10 PF13374.6 EGB05007.1 - 2.8e-110 357.7 59.4 1.2e-10 40.9 0.9 15.4 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05007.1 - 6.1e-59 191.8 53.4 7.1e-08 32.0 0.2 14.6 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05007.1 - 2e-50 166.6 40.4 1.9e-07 30.6 0.3 13.9 14 0 0 14 14 13 10 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05007.1 - 1.3e-44 146.7 50.6 5.8e-06 26.0 0.5 14.0 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05007.1 - 3.1e-38 126.8 39.8 0.00022 21.2 0.1 14.4 15 0 0 15 15 14 9 Tetratricopeptide repeat Glutaredoxin2_C PF04399.13 EGB05007.1 - 2.8e-31 108.0 0.0 7.4e-31 106.7 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain TPR_4 PF07721.14 EGB05007.1 - 5.4e-23 79.2 26.4 0.038 14.6 0.1 13.7 14 0 0 14 14 12 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05007.1 - 2.2e-18 65.6 32.0 0.064 13.9 0.2 13.0 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_5 PF12688.7 EGB05007.1 - 1.5e-17 64.0 28.9 0.0083 16.4 0.1 9.3 3 2 7 10 10 10 5 Tetratrico peptide repeat TPR_MalT PF17874.1 EGB05007.1 - 3.3e-17 62.9 12.3 2.3e-06 27.2 0.5 4.2 2 1 2 4 4 4 4 MalT-like TPR region TPR_14 PF13428.6 EGB05007.1 - 5.1e-16 58.0 53.5 0.11 13.3 0.3 13.9 12 2 1 13 13 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05007.1 - 3.3e-13 49.1 40.3 0.00047 19.8 0.2 10.3 11 2 1 12 12 10 4 TPR repeat TPR_16 PF13432.6 EGB05007.1 - 3e-11 43.8 64.8 8.7e-06 26.3 6.2 9.8 6 3 4 10 10 9 4 Tetratricopeptide repeat TPR_3 PF07720.12 EGB05007.1 - 3.2e-08 33.4 13.3 0.18 11.8 0.1 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat Mob_Pre PF01076.19 EGB05007.1 - 1.1e-05 25.3 0.3 3.1 7.6 0.0 5.8 6 1 1 7 7 7 1 Plasmid recombination enzyme YlmH_RBD PF17774.1 EGB05007.1 - 3.2e-05 24.1 3.5 25 5.2 0.0 6.6 7 2 2 9 9 6 0 Putative RNA-binding domain in YlmH Pox_H7 PF04787.12 EGB05007.1 - 4.6e-05 24.0 0.0 2.8 8.4 0.0 3.8 2 1 1 3 3 3 1 Late protein H7 Fis1_TPR_C PF14853.6 EGB05007.1 - 0.0008 19.4 17.4 1.1 9.3 0.2 6.3 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat SMBP PF16785.5 EGB05007.1 - 0.0035 17.5 6.6 13 6.1 0.1 5.2 3 1 1 5 5 5 0 Small metal-binding protein GST_N_3 PF13417.6 EGB05007.1 - 0.0044 17.4 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RelA_SpoT PF04607.17 EGB05007.1 - 0.019 15.2 0.0 0.066 13.5 0.0 1.9 3 0 0 3 3 1 0 Region found in RelA / SpoT proteins TPR_17 PF13431.6 EGB05007.1 - 0.026 14.9 30.0 49 4.6 0.0 12.4 14 0 0 14 14 12 0 Tetratricopeptide repeat Sel1 PF08238.12 EGB05007.1 - 0.039 14.6 17.9 8.3 7.2 0.1 8.2 7 0 0 7 7 7 0 Sel1 repeat TPR_19 PF14559.6 EGB05007.1 - 0.04 14.4 44.5 1.5 9.4 1.2 9.1 7 2 3 11 11 8 0 Tetratricopeptide repeat TAtT PF16811.5 EGB05007.1 - 0.042 13.1 14.2 2.4 7.4 0.1 5.6 4 2 2 6 6 6 0 TRAP transporter T-component DUF3322 PF11795.8 EGB05007.1 - 0.12 12.3 1.1 30 4.5 0.0 4.1 4 1 1 5 5 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) GST_N_2 PF13409.6 EGB05007.1 - 0.18 12.1 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MIT PF04212.18 EGB05007.1 - 0.54 10.4 10.7 96 3.2 0.1 5.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 EGB05007.1 - 2.1 8.6 34.4 1 9.5 0.8 9.6 5 3 5 10 10 10 0 Tetratricopeptide repeat AAA_6 PF12774.7 EGB05008.1 - 3.3e-48 164.4 0.0 3.9e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 EGB05008.1 - 0.00014 21.9 0.0 0.048 13.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGB05009.1 - 6.4e-34 117.0 0.0 7.1e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EGB05009.1 - 1.3e-05 25.4 0.0 1.6e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGB05009.1 - 2.3e-05 24.4 0.0 3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGB05009.1 - 7.5e-05 23.2 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB05009.1 - 0.00026 21.4 0.1 0.0039 17.6 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EGB05009.1 - 0.00031 20.2 0.1 0.00043 19.7 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGB05009.1 - 0.006 16.8 0.0 0.0079 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB05009.1 - 0.047 14.0 0.2 0.088 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGB05009.1 - 0.057 13.2 0.1 0.083 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGB05009.1 - 0.077 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EGB05009.1 - 0.11 12.3 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 EGB05009.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Dynein_C PF18199.1 EGB05010.1 - 9.5e-66 222.1 0.0 1.6e-65 221.3 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 EGB05010.1 - 1.7e-36 125.5 0.0 3e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_8 PF12780.7 EGB05010.1 - 2.9e-36 125.1 0.0 5.4e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGB05010.1 - 4.5e-25 88.1 0.3 1.6e-24 86.3 0.4 1.8 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 EGB05010.1 - 5.8e-20 71.6 0.1 1.3e-18 67.2 0.0 2.7 2 1 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGB05010.1 - 2e-12 46.8 0.0 3.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 EGB05010.1 - 1e-05 25.6 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Spc7 PF08317.11 EGB05010.1 - 3 6.6 6.3 3.2 6.5 1.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Mito_carr PF00153.27 EGB05011.1 - 3e-62 206.6 4.0 9.3e-21 73.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.8 EGB05011.1 - 0.082 13.3 1.9 4.1 7.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) Serine_protease PF18405.1 EGB05011.1 - 0.61 9.2 3.2 3.8 6.6 0.0 3.4 4 1 0 4 4 4 0 Gammaproteobacterial serine protease DUF21 PF01595.20 EGB05012.1 - 1.7e-22 80.0 0.1 2.8e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGB05012.1 - 2.7e-18 66.1 0.2 1.7e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.17 EGB05012.1 - 1.9e-09 37.4 0.0 5.2e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Transporter associated domain SCAMP PF04144.13 EGB05012.1 - 0.018 15.4 1.2 0.02 15.2 0.0 1.6 2 0 0 2 2 2 0 SCAMP family DUF2721 PF11026.8 EGB05012.1 - 1.4 8.8 4.9 4 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) LIN37 PF15306.6 EGB05013.1 - 0.016 15.5 2.6 0.87 9.8 0.1 2.3 1 1 1 2 2 2 0 LIN37 NIPSNAP PF07978.13 EGB05013.1 - 0.66 10.2 3.4 0.86 9.9 0.1 2.5 3 0 0 3 3 3 0 NIPSNAP TPT PF03151.16 EGB05015.1 - 3.6e-09 36.4 14.7 6.5e-09 35.6 14.7 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family PQ-loop PF04193.14 EGB05015.1 - 9 6.1 10.0 0.53 10.1 0.3 3.6 3 1 1 4 4 4 0 PQ loop repeat TRAPPC-Trs85 PF12739.7 EGB05016.1 - 2.2e-24 86.2 0.0 7.6e-24 84.4 0.0 1.7 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CSN8_PSD8_EIF3K PF10075.9 EGB05017.1 - 4e-23 82.0 0.0 6.1e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EGB05017.1 - 0.00061 19.3 0.4 0.00081 18.9 0.4 1.1 1 0 0 1 1 1 1 SAC3/GANP family AbiJ_NTD4 PF18863.1 EGB05017.1 - 0.033 14.7 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 NUDE_C PF04880.13 EGB05018.1 - 0.069 13.6 4.6 0.14 12.6 4.6 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region WD40 PF00400.32 EGB05019.1 - 0.0059 17.4 12.1 3.4 8.7 0.0 5.5 6 1 0 6 6 6 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGB05019.1 - 0.012 14.6 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 EGB05019.1 - 0.019 14.3 0.0 0.94 8.7 0.0 2.6 2 1 1 3 3 3 0 CPSF A subunit region PP2C PF00481.21 EGB05022.1 - 8.6e-14 51.8 1.8 3.1e-08 33.6 0.2 2.6 2 1 0 2 2 2 2 Protein phosphatase 2C Not3 PF04065.15 EGB05023.1 - 3.8e-84 281.7 26.7 3.8e-84 281.7 26.7 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGB05023.1 - 4.7e-12 46.1 7.8 9.2e-10 38.7 1.4 2.9 1 1 1 2 2 2 2 NOT2 / NOT3 / NOT5 family Kinesin PF00225.23 EGB05024.1 - 9.1e-53 179.3 1.6 3.5e-52 177.4 1.6 1.9 1 1 0 1 1 1 1 Kinesin motor domain SBD_N PF07005.11 EGB05024.1 - 0.019 14.7 0.5 5.9 6.5 0.1 2.7 2 0 0 2 2 2 0 Sugar-binding N-terminal domain TMF_DNA_bd PF12329.8 EGB05024.1 - 0.026 14.5 2.1 0.026 14.5 2.1 4.3 4 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding TPR_19 PF14559.6 EGB05025.1 - 5.9e-39 132.4 65.3 7e-05 23.3 0.8 14.2 10 4 5 15 15 15 13 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05025.1 - 5.6e-22 76.0 76.6 0.0007 19.5 0.9 18.2 19 0 0 19 19 18 7 Tetratricopeptide repeat TPR_14 PF13428.6 EGB05025.1 - 3.8e-19 67.7 79.2 0.0032 18.2 0.1 20.2 13 7 10 23 23 22 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05025.1 - 1.7e-17 62.1 49.6 0.041 14.1 0.2 16.5 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05025.1 - 2.1e-16 59.0 64.3 0.00011 21.8 0.5 16.1 17 0 0 17 17 17 6 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05025.1 - 1.4e-12 48.0 59.7 0.13 12.9 0.1 14.7 10 7 6 17 17 15 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB05025.1 - 2.7e-12 46.7 42.2 0.068 13.4 0.3 10.2 9 2 1 10 10 10 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGB05025.1 - 3.1e-12 46.6 72.6 0.11 12.8 1.2 14.6 11 4 4 15 15 15 9 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05025.1 - 1.3e-10 40.7 30.7 0.031 14.0 1.6 10.9 11 3 3 14 14 14 4 TPR repeat TPR_9 PF13371.6 EGB05025.1 - 6.4e-05 23.0 42.7 0.014 15.6 0.2 8.3 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05025.1 - 0.001 18.9 42.4 1.6 9.0 0.2 13.0 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05025.1 - 0.0057 17.2 50.7 0.88 10.3 0.0 14.8 18 2 0 18 18 13 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05025.1 - 0.0072 16.6 29.4 0.89 10.1 0.2 11.3 11 0 0 11 11 11 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGB05025.1 - 0.1 12.3 21.2 0.23 11.1 0.0 7.5 8 0 0 8 8 8 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF2379 PF09543.10 EGB05025.1 - 0.37 11.0 7.6 0.36 11.0 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2379) COP-gamma_platf PF08752.10 EGB05026.1 - 7.9e-25 87.8 0.0 1.6e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Vps39_2 PF10367.9 EGB05026.1 - 4.1e-06 27.2 0.2 9.2e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EGB05026.1 - 0.00063 20.0 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 EGB05026.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 EGB05026.1 - 0.0013 18.6 0.1 0.0031 17.4 0.1 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS CPBP PF02517.16 EGB05027.1 - 1.7e-11 44.3 2.5 6.8e-11 42.4 2.5 2.1 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Exostosin PF03016.15 EGB05030.1 - 3.3e-05 23.2 0.0 5.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Cupin_4 PF08007.12 EGB05031.1 - 6.5e-28 98.1 0.0 1e-27 97.5 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EGB05031.1 - 5.6e-07 29.5 0.0 0.032 13.9 0.0 2.1 1 1 1 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 EGB05031.1 - 0.0074 16.0 0.0 0.047 13.4 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EGB05031.1 - 0.075 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cupin Metallophos PF00149.28 EGB05032.1 - 1.4e-18 68.2 0.3 2.3e-18 67.4 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EGB05032.1 - 2.3e-12 47.6 0.2 6.2e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGB05032.1 - 0.00042 20.5 0.0 0.0011 19.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pur_ac_phosph_N PF16656.5 EGB05032.1 - 0.0014 19.1 0.0 0.0031 18.1 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PGA_cap PF09587.10 EGB05032.1 - 0.0068 15.9 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap DUF2937 PF11157.8 EGB05033.1 - 0.0049 16.6 7.4 0.0049 16.6 7.4 3.5 2 1 0 3 3 3 1 Protein of unknown function (DUF2937) Siah-Interact_N PF09032.11 EGB05033.1 - 3.9 7.9 7.8 0.52 10.7 0.3 3.1 3 1 1 4 4 4 0 Siah interacting protein, N terminal UbiA PF01040.18 EGB05034.1 - 7.8e-36 123.7 6.6 1.6e-35 122.6 6.6 1.5 1 0 0 1 1 1 1 UbiA prenyltransferase family Lipase_GDSL PF00657.22 EGB05036.1 - 0.026 14.5 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Trypan_PARP PF05887.11 EGB05036.1 - 2.1 8.3 14.1 0.074 13.0 7.5 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PBP1_TM PF14812.6 EGB05036.1 - 5.8 7.4 10.9 1.5 9.3 2.6 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rieske PF00355.26 EGB05037.1 - 1.8e-13 50.2 0.2 3.1e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain KASH_CCD PF14662.6 EGB05038.1 - 3.2e-06 27.1 43.7 0.013 15.4 15.1 3.6 1 1 2 3 3 3 3 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 EGB05038.1 - 0.00017 21.8 35.7 0.1 12.8 4.2 4.8 1 1 3 4 4 4 4 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 EGB05038.1 - 0.00029 21.2 52.2 0.94 10.0 3.3 6.7 1 1 6 7 7 7 3 Cell division protein ZapB EF-hand_6 PF13405.6 EGB05038.1 - 0.00031 20.4 0.0 0.00098 18.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain bZIP_1 PF00170.21 EGB05038.1 - 0.00068 19.7 38.3 0.6 10.3 2.1 7.3 1 1 6 8 8 8 3 bZIP transcription factor EF-hand_5 PF13202.6 EGB05038.1 - 0.00081 18.8 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 EF hand ADIP PF11559.8 EGB05038.1 - 0.0013 18.9 37.3 0.025 14.7 8.6 4.5 1 1 3 4 4 4 2 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 EGB05038.1 - 0.0017 17.7 34.9 0.048 13.0 11.3 4.0 1 1 4 5 5 5 2 Protein of unknown function (DUF3450) EF-hand_1 PF00036.32 EGB05038.1 - 0.0025 17.3 0.0 0.007 15.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGB05038.1 - 0.0027 18.1 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair DivIC PF04977.15 EGB05038.1 - 0.0045 16.7 38.5 0.79 9.5 2.8 6.7 1 1 5 6 6 6 2 Septum formation initiator DUF1664 PF07889.12 EGB05038.1 - 0.007 16.4 18.0 0.079 13.0 0.2 5.1 3 1 1 5 5 4 1 Protein of unknown function (DUF1664) APG6_N PF17675.1 EGB05038.1 - 0.009 16.5 44.1 0.014 16.0 13.6 3.5 1 1 2 3 3 3 1 Apg6 coiled-coil region MbeD_MobD PF04899.12 EGB05038.1 - 0.015 15.4 10.6 10 6.3 0.0 5.4 2 1 2 4 4 4 0 MbeD/MobD like Exostosin PF03016.15 EGB05038.1 - 0.017 14.4 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Exostosin family TMCO5 PF14992.6 EGB05038.1 - 0.05 13.2 35.3 1.1 8.7 18.6 2.8 1 1 1 2 2 2 0 TMCO5 family DUF2205 PF10224.9 EGB05038.1 - 0.069 13.1 0.0 0.069 13.1 0.0 5.1 1 1 5 6 6 6 0 Short coiled-coil protein YabA PF06156.13 EGB05038.1 - 0.076 13.7 32.2 3.3 8.4 8.0 5.0 1 1 3 4 4 4 0 Initiation control protein YabA Leu_zip PF15294.6 EGB05038.1 - 0.11 12.0 39.2 0.94 8.9 15.1 3.3 1 1 2 3 3 3 0 Leucine zipper NPV_P10 PF05531.12 EGB05038.1 - 0.16 12.5 10.2 3 8.4 1.0 4.6 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 EGB05038.1 - 0.18 10.3 26.4 0.11 11.0 12.5 2.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF4618 PF15397.6 EGB05038.1 - 0.23 10.9 23.0 0.42 10.0 0.0 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4618) CALCOCO1 PF07888.11 EGB05038.1 - 0.29 9.9 35.0 0.65 8.8 15.2 2.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HALZ PF02183.18 EGB05038.1 - 0.31 11.3 21.6 1.8 8.9 0.4 6.7 3 2 4 7 7 7 0 Homeobox associated leucine zipper Taxilin PF09728.9 EGB05038.1 - 0.33 10.1 34.9 0.66 9.1 34.5 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein ATG16 PF08614.11 EGB05038.1 - 0.43 10.8 40.7 0.64 10.2 8.2 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Mod_r PF07200.13 EGB05038.1 - 0.43 10.7 36.3 4.4 7.4 9.0 4.8 1 1 4 5 5 5 0 Modifier of rudimentary (Mod(r)) protein ERM PF00769.19 EGB05038.1 - 0.66 9.7 55.6 0.99 9.2 27.5 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family UPF0449 PF15136.6 EGB05038.1 - 0.76 10.3 23.9 2.9 8.4 0.8 4.9 1 1 4 5 5 5 0 Uncharacterised protein family UPF0449 Jnk-SapK_ap_N PF09744.9 EGB05038.1 - 1.1 9.5 35.5 0.46 10.7 15.0 3.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 EGB05038.1 - 1.2 8.2 23.0 0.39 9.8 6.3 2.4 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 EGB05038.1 - 1.8 9.0 37.0 7.4 7.0 10.3 4.3 1 1 3 4 4 4 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 EGB05038.1 - 2.1 8.4 40.1 0.07 13.1 1.9 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 EGB05038.1 - 2.2 8.4 33.1 1.3 9.0 7.6 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 EGB05038.1 - 2.3 8.6 30.2 14 6.1 2.6 5.3 2 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Scaffolding_pro PF11418.8 EGB05038.1 - 2.4 8.8 7.5 15 6.2 0.8 4.1 1 1 4 5 5 5 0 Phi29 scaffolding protein Rootletin PF15035.6 EGB05038.1 - 3.8 7.5 41.1 0.98 9.4 13.2 4.1 2 1 2 4 4 3 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.11 EGB05038.1 - 5.5 7.5 21.1 10 6.6 1.5 5.7 3 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Sec34 PF04136.15 EGB05038.1 - 6.2 6.7 15.8 0.99 9.3 1.8 3.4 1 1 2 4 4 4 0 Sec34-like family Spc7 PF08317.11 EGB05038.1 - 7.2 5.4 40.5 1.2 8.0 15.8 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 EGB05038.1 - 7.5 7.1 18.0 0.21 12.0 3.1 4.3 1 1 2 4 4 4 0 Snapin/Pallidin GIT_CC PF16559.5 EGB05038.1 - 7.6 6.5 19.2 21 5.1 0.5 5.8 2 1 5 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF812 PF05667.11 EGB05038.1 - 7.8 5.2 37.9 11 4.8 11.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) bZIP_Maf PF03131.17 EGB05038.1 - 8.9 6.9 25.6 25 5.5 1.0 6.1 2 1 3 6 6 6 0 bZIP Maf transcription factor SSF PF00474.17 EGB05039.1 - 1.3e-06 27.6 8.0 1.4e-06 27.4 8.0 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family FKBP_C PF00254.28 EGB05040.1 - 1.9e-21 76.2 0.0 2.1e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Aminotran_1_2 PF00155.21 EGB05041.1 - 1.1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PA28_beta PF02252.18 EGB05041.1 - 0.008 15.9 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PFK PF00365.20 EGB05042.1 - 1.2e-55 188.8 0.8 1.6e-55 188.4 0.4 1.4 2 0 0 2 2 2 1 Phosphofructokinase DAGK_cat PF00781.24 EGB05042.1 - 0.0027 17.3 0.0 0.0085 15.7 0.1 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain LSDAT_euk PF18139.1 EGB05042.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM zf_C2H2_10 PF18414.1 EGB05043.1 - 0.13 11.8 0.2 0.3 10.7 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger AMP-binding PF00501.28 EGB05044.1 - 1.1e-54 185.7 0.5 2.1e-54 184.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 EGB05044.1 - 3.9e-05 23.9 0.1 0.00014 22.1 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Tub PF01167.18 EGB05045.1 - 6e-25 88.4 0.0 7e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Tub family HEAT PF02985.22 EGB05046.1 - 0.0039 17.3 17.4 10 6.7 0.0 8.2 8 0 0 8 8 8 2 HEAT repeat TSKS PF15358.6 EGB05046.1 - 0.025 13.0 1.0 0.044 12.2 1.0 1.3 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DUF416 PF04222.12 EGB05046.1 - 0.16 11.3 0.1 0.39 10.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF416) IFRD PF05004.13 EGB05046.1 - 0.58 9.2 0.0 0.58 9.2 0.0 2.7 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) PROCN PF08083.11 EGB05047.1 - 1.9e-234 777.8 6.9 2.9e-234 777.2 6.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGB05047.1 - 2.9e-129 429.5 0.4 4.9e-129 428.8 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGB05047.1 - 3.4e-89 296.9 2.6 9.1e-89 295.5 2.6 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGB05047.1 - 1.9e-86 287.6 2.8 5e-86 286.3 2.8 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGB05047.1 - 1.9e-73 244.9 0.0 3.5e-73 244.0 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EGB05047.1 - 8.4e-52 174.3 0.0 2e-51 173.0 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 EGB05047.1 - 2.5e-47 159.1 0.3 6.8e-47 157.7 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 EGB05047.1 - 5e-07 29.7 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DASH_Spc34 PF08657.10 EGB05048.1 - 0.22 11.3 2.1 0.37 10.5 0.8 1.8 1 1 1 2 2 2 0 DASH complex subunit Spc34 TACC_C PF05010.14 EGB05048.1 - 0.73 9.6 11.1 9.1 6.0 7.3 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GASA PF02704.14 EGB05048.1 - 9.7 6.4 17.5 14 5.9 7.4 2.4 1 1 1 2 2 2 0 Gibberellin regulated protein DASH_Spc34 PF08657.10 EGB05049.1 - 0.095 12.5 2.9 0.42 10.4 2.8 2.0 1 1 0 1 1 1 0 DASH complex subunit Spc34 TBD PF12845.7 EGB05049.1 - 0.13 12.1 0.3 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 TBD domain eIF3_N PF09440.10 EGB05049.1 - 0.62 10.5 4.7 0.35 11.3 1.1 2.2 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Proteasome PF00227.26 EGB05050.1 - 5.1e-46 156.6 1.0 6.1e-46 156.3 1.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 EGB05051.1 - 6.4e-63 212.6 0.0 7.5e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05051.1 - 2.2e-16 59.9 0.0 3.2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05051.1 - 1.1e-06 28.8 0.0 3.8e-05 23.7 0.3 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB05051.1 - 0.014 14.2 0.3 0.03 13.1 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGB05051.1 - 0.055 12.8 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB05051.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EGB05051.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box-like PF12937.7 EGB05055.1 - 0.01 15.7 1.3 0.022 14.6 1.3 1.5 1 0 0 1 1 1 0 F-box-like RNA_pol_Rpb5_C PF01191.19 EGB05056.1 - 4.9e-33 112.8 0.2 1e-32 111.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EGB05056.1 - 2.8e-26 91.9 0.4 4.4e-26 91.3 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EGB05056.1 - 0.03 14.4 0.1 0.12 12.4 0.0 1.9 2 1 0 2 2 2 0 Restriction endonuclease NPIP PF06409.11 EGB05056.1 - 0.036 13.1 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) NAD_binding_10 PF13460.6 EGB05056.1 - 0.17 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Sugar_tr PF00083.24 EGB05057.1 - 1.5e-67 228.4 23.8 1.8e-67 228.2 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB05057.1 - 9e-23 80.8 53.5 1.5e-15 57.0 20.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGB05057.1 - 8.1e-05 21.2 18.6 0.00083 17.9 4.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UQ_con PF00179.26 EGB05058.1 - 1.1e-43 148.2 0.0 1.3e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGB05058.1 - 0.054 13.2 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B TPR_MLP1_2 PF07926.12 EGB05060.1 - 0.00034 20.7 8.5 0.00034 20.7 8.5 16.2 9 4 7 18 18 18 3 TPR/MLP1/MLP2-like protein Ribonuclease_3 PF00636.26 EGB05060.1 - 4.4 8.0 6.7 3.8 8.2 0.7 3.5 2 0 0 2 2 2 0 Ribonuclease III domain Atg8 PF02991.16 EGB05062.1 - 1e-36 125.3 1.3 5.1e-36 123.0 1.3 1.8 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGB05062.1 - 0.0048 17.3 0.0 0.0067 16.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 TGT_C1 PF14809.6 EGB05062.1 - 0.38 11.1 0.1 0.38 11.1 0.1 1.9 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation ELO PF01151.18 EGB05063.1 - 1.3e-58 198.5 15.3 1.4e-58 198.4 15.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Epimerase PF01370.21 EGB05064.1 - 7.6e-24 84.5 0.0 4.4e-23 82.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB05064.1 - 4.3e-17 62.5 0.0 1.4e-15 57.6 0.0 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGB05064.1 - 1.3e-05 24.5 0.0 0.0019 17.4 0.1 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein DEAD PF00270.29 EGB05065.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGB05065.1 - 0.0003 21.1 0.0 0.00068 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGB05065.1 - 0.0036 16.4 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGB05065.1 - 0.0041 16.5 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.6 EGB05065.1 - 0.0059 16.9 0.0 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB05065.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGB05065.1 - 0.036 13.4 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 EGB05065.1 - 0.085 13.0 0.0 0.085 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF3572 PF12096.8 EGB05065.1 - 0.088 13.0 0.2 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) AAA_29 PF13555.6 EGB05065.1 - 0.094 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EGB05065.1 - 0.096 11.7 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 EGB05065.1 - 0.17 11.3 0.0 0.47 9.9 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein PrmA PF06325.13 EGB05066.1 - 1.9e-13 50.5 0.7 2.3e-13 50.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB05066.1 - 9.6e-12 44.8 0.1 1.3e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB05066.1 - 9.9e-11 42.2 0.2 2.5e-10 40.9 0.2 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05066.1 - 2.2e-08 34.0 0.0 3.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB05066.1 - 6.9e-08 33.0 0.1 1.5e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB05066.1 - 3.1e-07 30.2 0.0 4.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EGB05066.1 - 7.6e-06 25.7 0.4 4.2e-05 23.3 0.4 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 EGB05066.1 - 9.4e-05 22.0 0.0 0.00014 21.5 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 EGB05066.1 - 0.00017 22.3 0.1 0.00028 21.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGB05066.1 - 0.00019 21.4 0.1 0.0003 20.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB05066.1 - 0.00035 20.4 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGB05066.1 - 0.00038 20.3 0.0 0.00051 19.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EGB05066.1 - 0.0012 18.6 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGB05066.1 - 0.0031 17.5 0.0 0.0046 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB05066.1 - 0.0042 16.4 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EGB05066.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FtsJ PF01728.19 EGB05066.1 - 0.017 15.2 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase NeA_P2 PF12312.8 EGB05066.1 - 0.037 13.5 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CMAS PF02353.20 EGB05066.1 - 0.084 12.2 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 EGB05066.1 - 0.16 11.7 0.1 0.22 11.2 0.1 1.1 1 0 0 1 1 1 0 Lysine methyltransferase AviRa PF11599.8 EGB05066.1 - 0.2 11.1 1.6 0.34 10.3 1.4 1.4 1 1 0 1 1 1 0 RRNA methyltransferase AviRa Pox_MCEL PF03291.16 EGB05066.1 - 0.26 10.4 0.2 0.37 9.9 0.2 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Pkinase PF00069.25 EGB05067.1 - 1.5e-22 80.3 0.0 1.6e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05067.1 - 3.4e-08 33.1 0.0 3.7e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05067.1 - 0.0069 16.3 0.1 0.0096 15.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB05067.1 - 0.045 13.1 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGB05067.1 - 0.22 10.8 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 EGB05068.1 - 1.3e-14 54.6 0.0 6.1e-06 26.7 0.0 3.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) EF-hand_7 PF13499.6 EGB05068.1 - 2.3e-13 50.4 1.1 7.1e-07 29.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB05068.1 - 3.4e-12 45.0 9.5 7.5e-05 22.0 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGB05068.1 - 2.1e-11 42.8 4.2 0.036 14.0 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB05068.1 - 5.7e-11 42.1 4.2 4.6e-05 23.2 0.2 3.7 3 0 0 3 3 3 2 EF-hand domain pair Ank_5 PF13857.6 EGB05068.1 - 4.9e-10 39.5 1.0 0.00077 19.7 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) EF-hand_5 PF13202.6 EGB05068.1 - 3.1e-08 32.7 11.4 0.016 14.7 0.1 4.1 4 0 0 4 4 4 3 EF hand Ank_3 PF13606.6 EGB05068.1 - 1.1e-07 31.5 0.2 4.8 8.1 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EGB05068.1 - 3.3e-06 27.5 0.0 0.0011 19.4 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB05068.1 - 0.00013 22.2 1.7 5.5 7.6 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat DUF604 PF04646.12 EGB05068.1 - 0.078 12.4 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 ALG3 PF05208.13 EGB05070.1 - 5.1e-85 286.0 0.3 1.1e-84 284.9 0.3 1.5 1 1 0 1 1 1 1 ALG3 protein Fasciclin PF02469.22 EGB05070.1 - 2.1e-12 47.4 0.0 3.7e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain WD40 PF00400.32 EGB05070.1 - 0.00016 22.4 10.3 2.1 9.4 0.0 6.8 7 0 0 7 7 7 2 WD domain, G-beta repeat Mannosyl_trans PF05007.13 EGB05070.1 - 0.00098 19.1 1.8 0.63 9.8 0.1 2.2 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) Alg6_Alg8 PF03155.15 EGB05070.1 - 0.0037 16.3 1.8 0.006 15.6 1.8 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Na_Ca_ex PF01699.24 EGB05071.1 - 7.3e-35 120.2 28.6 6.1e-19 68.5 11.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF5337 PF17272.2 EGB05071.1 - 0.79 9.6 7.4 1.4 8.8 5.5 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF2749 PF10907.8 EGB05071.1 - 4.5 7.5 12.8 3.6 7.8 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2749) DAO_C PF16901.5 EGB05072.1 - 5.3e-40 136.2 0.1 1.1e-39 135.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 EGB05072.1 - 7.1e-40 137.7 0.2 1.5e-39 136.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase EF-hand_1 PF00036.32 EGB05072.1 - 1.7e-10 39.7 0.0 1.2e-05 24.5 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB05072.1 - 5.6e-10 38.3 0.0 0.0024 17.7 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB05072.1 - 2.7e-09 37.3 0.0 5.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 EGB05072.1 - 2.1e-07 30.4 4.2 4.1e-06 26.1 4.2 2.2 1 1 0 1 1 1 1 FAD binding domain EF-hand_8 PF13833.6 EGB05072.1 - 5.5e-05 22.9 0.2 0.0074 16.1 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB05072.1 - 0.0013 18.2 0.0 0.057 12.9 0.0 2.5 2 0 0 2 2 2 1 EF hand Pyr_redox_2 PF07992.14 EGB05072.1 - 0.021 14.1 0.0 0.061 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB05072.1 - 0.025 13.8 0.6 0.65 9.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain DUF1962 PF09227.10 EGB05072.1 - 0.056 13.8 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) FAD_oxidored PF12831.7 EGB05072.1 - 0.071 12.4 3.8 0.063 12.6 1.9 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase MORN PF02493.20 EGB05074.1 - 6.7e-35 116.9 41.7 4.5e-06 26.2 1.6 7.1 7 0 0 7 7 7 7 MORN repeat Nsp3_PL2pro PF12124.8 EGB05074.1 - 0.036 13.8 1.6 0.23 11.2 0.3 2.3 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain DUF3048_C PF17479.2 EGB05074.1 - 0.95 9.9 11.8 7.8 6.9 1.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain PP2C PF00481.21 EGB05075.1 - 2.5e-40 138.8 0.0 3.3e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB05075.1 - 1.9e-08 34.2 0.0 4.7e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C cNMP_binding PF00027.29 EGB05076.1 - 6.7e-36 122.2 0.0 7.1e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGB05077.1 - 2.3e-21 76.3 0.0 2.7e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05077.1 - 1.4e-12 47.5 0.0 1.6e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05077.1 - 0.17 11.1 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ABC_membrane PF00664.23 EGB05078.1 - 5.2e-40 137.8 0.1 6.4e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB05078.1 - 2.8e-28 99.2 0.0 5.2e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB05078.1 - 2.4e-06 28.0 1.9 3.7e-06 27.4 0.5 2.0 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EGB05078.1 - 3.1e-05 23.3 0.1 5.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin SMC_N PF02463.19 EGB05078.1 - 0.00011 21.7 0.2 0.0045 16.5 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGB05078.1 - 0.00097 19.4 0.0 0.0034 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EGB05078.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.6 EGB05078.1 - 0.0039 16.9 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EGB05078.1 - 0.0044 17.2 0.0 0.0099 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGB05078.1 - 0.0068 16.3 0.1 1.9 8.2 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGB05078.1 - 0.019 14.5 0.1 0.5 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGB05078.1 - 0.046 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGB05078.1 - 0.062 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB05078.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGB05078.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGB05078.1 - 0.082 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EGB05078.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 EGB05078.1 - 0.22 10.7 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 EGB05078.1 - 0.24 10.9 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EGB05078.1 - 2.5 7.8 7.0 0.89 9.2 1.9 2.5 2 1 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EGB05079.1 - 5.5e-129 429.8 0.0 3.8e-126 420.5 0.0 4.4 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 EGB05079.1 - 1.2e-91 306.6 0.0 2.8e-91 305.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 EGB05079.1 - 9.6e-90 301.5 8.4 9.6e-90 301.5 8.4 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGB05079.1 - 1.5e-77 259.7 0.0 5.2e-77 257.9 0.0 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 EGB05079.1 - 2e-72 244.1 13.0 7e-72 242.3 13.0 2.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EGB05079.1 - 2.9e-68 230.3 0.0 6.2e-68 229.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGB05079.1 - 2.2e-61 206.5 0.4 9.4e-58 194.7 0.0 4.4 5 0 0 5 5 4 1 P-loop containing dynein motor region DUF572 PF04502.13 EGB05079.1 - 8.7e-46 157.1 0.0 8.7e-46 157.1 0.0 5.1 4 1 0 4 4 3 1 Family of unknown function (DUF572) AAA_lid_11 PF18198.1 EGB05079.1 - 5.8e-44 149.8 0.0 1.6e-43 148.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain RRP36 PF06102.12 EGB05079.1 - 2.2e-35 122.1 20.0 2.2e-35 122.1 20.0 5.3 5 1 0 5 5 1 1 rRNA biogenesis protein RRP36 Dynein_heavy PF03028.15 EGB05079.1 - 8e-35 119.5 0.1 3.4e-33 114.3 0.0 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EGB05079.1 - 1.1e-23 83.7 0.0 3.3e-11 43.3 0.0 6.0 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGB05079.1 - 4.3e-19 68.6 0.0 2.2e-18 66.3 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EGB05079.1 - 1.7e-15 57.3 3.1 7.4e-15 55.2 1.9 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGB05079.1 - 6.4e-05 23.2 0.0 13 6.1 0.0 4.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EGB05079.1 - 0.00015 22.2 0.3 12 6.3 0.0 4.6 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB05079.1 - 0.00078 19.9 1.1 0.75 10.1 0.0 4.9 5 0 0 5 5 4 1 AAA ATPase domain Mg_chelatase PF01078.21 EGB05079.1 - 0.0045 16.4 0.5 0.29 10.5 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EGB05079.1 - 0.023 13.8 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 EGB05079.1 - 0.026 14.9 0.1 3.7 7.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGB05079.1 - 0.051 14.1 3.1 12 6.5 0.0 5.0 6 0 0 6 6 5 0 AAA domain AAA_29 PF13555.6 EGB05079.1 - 0.24 11.2 1.8 2.3 8.0 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EGB05079.1 - 0.33 11.1 6.4 1.6 8.9 0.0 4.2 4 0 0 4 4 3 0 AAA domain Ssu72 PF04722.13 EGB05079.1 - 0.54 9.8 3.6 0.33 10.5 0.0 2.5 3 0 0 3 3 3 0 Ssu72-like protein Patched PF02460.18 EGB05080.1 - 9.4e-32 110.0 19.5 3.9e-17 61.6 0.1 2.8 3 1 1 4 4 4 3 Patched family Sterol-sensing PF12349.8 EGB05080.1 - 7.7e-12 45.3 16.4 9.7e-10 38.5 1.5 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EGB05080.1 - 0.0027 16.7 33.8 0.13 11.2 14.7 3.2 2 2 0 2 2 2 2 MMPL family TPR_12 PF13424.6 EGB05081.1 - 1.1e-89 294.8 39.0 1.4e-18 66.9 1.2 8.3 4 3 4 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGB05081.1 - 2.7e-76 249.6 40.3 1.7e-10 40.4 0.6 12.4 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05081.1 - 2.1e-24 83.7 28.5 0.0035 17.3 0.3 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05081.1 - 1.2e-18 66.1 12.5 0.024 14.4 0.1 10.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05081.1 - 4.6e-18 63.8 27.1 0.005 16.9 0.4 10.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB05081.1 - 1.9e-14 53.8 9.3 2.5e-05 23.8 0.1 4.1 1 1 3 4 4 4 4 MalT-like TPR region TPR_8 PF13181.6 EGB05081.1 - 4.6e-14 51.4 12.5 0.42 11.0 0.0 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB05081.1 - 1.7e-09 37.7 44.6 1.9 9.5 0.5 10.4 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_4 PF07721.14 EGB05081.1 - 2.9e-05 24.3 40.6 0.094 13.4 1.7 9.5 9 0 0 9 9 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGB05081.1 - 0.00085 18.7 3.7 7.1 6.2 0.8 5.9 6 0 0 6 6 6 1 SHNi-TPR TPR_16 PF13432.6 EGB05081.1 - 0.0023 18.5 55.5 0.029 15.0 6.8 9.1 6 3 2 8 8 8 4 Tetratricopeptide repeat Chorion_S16 PF05836.12 EGB05081.1 - 0.0028 17.8 2.1 0.0028 17.8 2.1 2.2 2 0 0 2 2 1 1 Chorion protein S16 TPR_5 PF12688.7 EGB05081.1 - 0.0063 16.8 17.7 0.11 12.8 0.7 6.5 4 2 1 6 6 6 1 Tetratrico peptide repeat TPR_19 PF14559.6 EGB05081.1 - 0.012 16.1 29.4 0.023 15.2 2.4 7.3 5 3 3 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05081.1 - 0.05 14.0 10.5 1.7 9.2 0.3 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGB05081.1 - 3.1 7.9 5.3 1.2 9.2 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05081.1 - 8.1 7.3 8.3 21 6.0 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat JAB PF01398.21 EGB05082.1 - 1.9e-17 63.3 0.0 2.8e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGB05082.1 - 2.4e-12 47.3 0.0 3.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DEAD PF00270.29 EGB05083.1 - 1.2e-13 51.2 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 EGB05083.1 - 2.5e-07 30.9 5.6 2.5e-07 30.9 5.6 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGB05083.1 - 2.8e-07 30.3 5.6 5.6e-07 29.3 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB05083.1 - 3.9e-06 26.6 6.6 3.9e-06 26.6 6.6 2.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 EGB05083.1 - 4.9e-06 26.9 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EGB05083.1 - 0.00053 19.9 5.1 0.0011 18.8 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EGB05083.1 - 0.00061 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 EGB05083.1 - 0.0013 18.7 6.0 0.003 17.6 6.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGB05083.1 - 0.0017 18.6 4.9 0.0017 18.6 4.9 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain TPR_2 PF07719.17 EGB05083.1 - 0.0094 16.0 5.3 0.062 13.4 0.4 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Prok-RING_4 PF14447.6 EGB05083.1 - 0.012 15.5 7.0 0.025 14.4 7.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGB05083.1 - 0.02 14.6 3.2 0.048 13.4 3.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EGB05083.1 - 0.023 14.7 1.3 0.066 13.3 1.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_8 PF13181.6 EGB05083.1 - 0.024 14.8 0.5 0.26 11.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 EGB05083.1 - 0.031 14.4 6.4 0.075 13.2 6.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HHH_5 PF14520.6 EGB05083.1 - 0.16 12.6 0.2 0.73 10.5 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain zf-MYND PF01753.18 EGB05083.1 - 6.3 7.0 24.9 0.013 15.6 12.7 2.7 2 0 0 2 2 1 0 MYND finger Glutaredoxin2_C PF04399.13 EGB05084.1 - 8.3e-40 135.6 0.0 1.1e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 EGB05084.1 - 0.00017 21.9 0.0 0.00037 20.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB05084.1 - 0.0003 21.0 0.0 0.00091 19.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EGB05084.1 - 0.007 16.6 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin NinF PF05810.12 EGB05084.1 - 0.015 15.2 0.4 0.027 14.3 0.4 1.4 1 0 0 1 1 1 0 NinF protein Pkinase PF00069.25 EGB05085.1 - 5.8e-64 216.0 0.0 1.1e-63 215.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05085.1 - 1.2e-29 103.4 0.0 1.7e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05085.1 - 0.00093 19.2 0.2 0.0051 16.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB05085.1 - 0.0018 17.7 0.1 0.0042 16.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB05085.1 - 0.033 13.1 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Topo-VIb_trans PF09239.11 EGB05086.1 - 5.6e-17 62.0 0.0 4.2e-11 42.9 0.0 2.4 1 1 1 2 2 2 2 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.6 EGB05086.1 - 2.5e-06 27.4 0.5 0.00045 20.1 0.1 2.4 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGB05086.1 - 2.6e-05 24.7 0.0 0.00016 22.1 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2OG-FeII_Oxy_2 PF13532.6 EGB05087.1 - 1.9e-34 119.6 0.0 3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2H2_6 PF13912.6 EGB05087.1 - 0.012 15.5 0.4 0.029 14.4 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGB05087.1 - 0.019 15.7 0.4 0.053 14.4 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGB05087.1 - 0.05 14.1 0.4 0.1 13.1 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type AIM24 PF01987.17 EGB05088.1 - 6.1e-47 160.0 0.0 6.8e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Pkinase PF00069.25 EGB05089.1 - 7.9e-47 159.8 0.0 9e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05089.1 - 8.7e-26 90.8 0.0 1.1e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB05089.1 - 0.08 12.3 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CH PF00307.31 EGB05090.1 - 5.1e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain PDZ_2 PF13180.6 EGB05090.1 - 0.00076 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DinB_2 PF12867.7 EGB05090.1 - 2.2 8.8 16.9 2.8 8.5 0.1 5.4 5 0 0 5 5 5 0 DinB superfamily Sulfotransfer_2 PF03567.14 EGB05091.1 - 0.00019 21.5 0.0 0.00066 19.7 0.0 1.9 3 0 0 3 3 3 1 Sulfotransferase family peroxidase PF00141.23 EGB05091.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Peroxidase Caa3_CtaG PF09678.10 EGB05092.1 - 0.051 13.0 0.5 0.2 11.1 0.7 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF5600 PF18150.1 EGB05093.1 - 1e-26 93.6 0.0 1.9e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) PH PF00169.29 EGB05093.1 - 1.3e-18 67.4 0.0 5.5e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 PH domain Dynamin_N PF00350.23 EGB05093.1 - 1.3e-13 51.4 0.0 3.9e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB05093.1 - 1.1e-09 38.3 0.0 1.1e-08 35.2 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase PH_11 PF15413.6 EGB05093.1 - 4.5e-07 30.2 1.1 0.00011 22.6 0.3 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain EHD_N PF16880.5 EGB05093.1 - 2.4e-06 27.3 0.0 4.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein PH_8 PF15409.6 EGB05093.1 - 1.3e-05 25.4 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Roc PF08477.13 EGB05093.1 - 0.001 19.3 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGB05093.1 - 0.0055 16.3 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.18 EGB05093.1 - 0.011 15.2 0.0 0.41 10.1 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGB05093.1 - 0.06 13.2 0.0 29 4.5 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase AIG1 PF04548.16 EGB05093.1 - 0.066 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 EGB05093.1 - 0.07 12.7 0.0 0.22 11.0 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 EGB05093.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF455 PF04305.14 EGB05093.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) AAA_16 PF13191.6 EGB05093.1 - 0.11 12.9 0.1 1.1 9.6 0.0 2.5 2 2 0 2 2 2 0 AAA ATPase domain PH_3 PF14593.6 EGB05093.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 PH domain Lip_A_acyltrans PF03279.13 EGB05093.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Gtr1_RagA PF04670.12 EGB05093.1 - 0.24 10.7 0.3 2.1 7.7 0.3 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Hydrolase_3 PF08282.12 EGB05094.1 - 9.5e-24 84.5 0.0 8.6e-13 48.6 0.2 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase NUDIX PF00293.28 EGB05094.1 - 4.9e-18 65.4 0.1 1e-17 64.4 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain S6PP PF05116.13 EGB05094.1 - 1.6e-07 31.1 0.1 4.2e-07 29.8 0.1 1.5 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EGB05094.1 - 0.00024 21.4 4.3 0.00024 21.4 4.3 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase SH3_3 PF08239.11 EGB05094.1 - 0.003 17.8 0.1 0.0089 16.3 0.1 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Pkinase_Tyr PF07714.17 EGB05095.1 - 5.2e-55 186.5 0.0 6.1e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB05095.1 - 8.3e-42 143.4 0.0 1e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FH2 PF02181.23 EGB05096.1 - 3.7e-37 128.3 0.0 2.8e-33 115.5 0.0 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain CCDC53 PF10152.9 EGB05096.1 - 5.4e-10 39.9 7.3 2.9e-07 31.0 0.1 3.5 3 1 0 3 3 3 2 Subunit CCDC53 of WASH complex DUF1295 PF06966.12 EGB05097.1 - 4.9e-51 173.5 0.1 6.1e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EGB05097.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EGB05097.1 - 0.0012 19.2 0.0 0.0077 16.6 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGB05097.1 - 0.0054 17.1 2.0 0.011 16.2 0.0 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EGB05097.1 - 0.053 12.3 0.1 0.079 11.7 0.1 1.4 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family EF-hand_1 PF00036.32 EGB05098.1 - 1.6e-12 46.0 0.1 6.8e-06 25.3 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB05098.1 - 8.4e-11 42.2 0.0 9.2e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB05098.1 - 2.6e-09 36.1 0.6 0.0015 17.9 0.0 2.4 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB05098.1 - 2.1e-08 33.4 0.1 0.00063 19.5 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB05098.1 - 4.7e-08 32.8 0.2 2.4e-07 30.5 0.0 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB05098.1 - 0.00012 22.4 0.0 0.00013 22.3 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain Pkinase PF00069.25 EGB05099.1 - 2.9e-62 210.4 0.0 3.2e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05099.1 - 4.2e-29 101.6 0.0 6.1e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05099.1 - 0.021 14.1 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ank_4 PF13637.6 EGB05100.1 - 3.4e-26 91.3 3.3 1.7e-11 44.4 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB05100.1 - 6.5e-19 68.3 0.1 2.2e-18 66.6 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB05100.1 - 4.2e-16 57.4 0.1 1.1e-05 25.5 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB05100.1 - 3.3e-15 55.9 2.1 3.4e-08 33.6 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB05100.1 - 4.6e-15 55.3 0.7 6.1e-07 29.6 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat DUF1912 PF08930.10 EGB05100.1 - 0.058 13.5 0.1 2.8 8.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) HTH_16 PF12645.7 EGB05100.1 - 0.16 12.0 0.7 0.91 9.6 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain SpdB PF05122.13 EGB05100.1 - 0.76 10.0 3.5 19 5.5 0.3 2.3 2 0 0 2 2 2 0 Mobile element transfer protein PAS_9 PF13426.7 EGB05101.1 - 1.5e-15 57.3 0.1 2.7e-15 56.5 0.0 1.4 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 EGB05101.1 - 0.00035 20.8 0.0 0.00055 20.2 0.0 1.3 1 0 0 1 1 1 1 PAS fold bZIP_2 PF07716.15 EGB05101.1 - 0.0021 18.1 6.9 0.005 16.9 6.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PAS_4 PF08448.10 EGB05101.1 - 0.0033 17.7 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold bZIP_1 PF00170.21 EGB05101.1 - 0.0075 16.3 3.9 0.012 15.7 3.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.25 EGB05101.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.8 1 1 1 2 2 2 0 PAS fold RNR_inhib PF08591.10 EGB05101.1 - 0.1 13.9 0.1 0.58 11.5 0.0 2.0 2 0 0 2 2 2 0 Ribonucleotide reductase inhibitor EF-hand_7 PF13499.6 EGB05103.1 - 8.3e-09 35.8 0.1 1.6e-05 25.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB05103.1 - 1.2e-07 30.7 1.6 0.15 11.6 0.0 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB05103.1 - 1e-06 28.2 0.3 0.2 11.7 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain C2 PF00168.30 EGB05103.1 - 2.4e-05 24.6 0.0 9.5e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 C2 domain EF-hand_8 PF13833.6 EGB05103.1 - 0.19 11.6 0.9 3.6 7.5 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain pair FPL PF09758.9 EGB05104.1 - 7.6e-44 149.3 0.0 1e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein CMS1 PF14617.6 EGB05106.1 - 9.6e-08 31.7 0.1 9.6e-08 31.7 0.1 2.8 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Peptidase_C97 PF05903.14 EGB05106.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Ydc2-catalyt PF09159.10 EGB05106.1 - 0.041 13.6 0.6 0.064 13.0 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 RNA_polI_A34 PF08208.11 EGB05106.1 - 0.39 10.8 18.8 0.76 9.8 18.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 UDPGT PF00201.18 EGB05107.1 - 5.1e-11 42.0 0.1 1.5e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase FTZ PF03867.14 EGB05107.1 - 0.064 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Cpn60_TCP1 PF00118.24 EGB05108.1 - 7.9e-162 539.3 3.0 9e-162 539.1 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mito_carr PF00153.27 EGB05109.1 - 1.3e-46 156.5 1.4 6.2e-16 58.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FG-GAP_2 PF14312.6 EGB05110.1 - 9.2e-23 80.2 57.2 1e-05 25.7 5.1 5.8 6 0 0 6 6 6 5 FG-GAP repeat Kelch_6 PF13964.6 EGB05110.1 - 4.8e-07 29.8 2.5 0.41 11.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Ran_BP1 PF00638.18 EGB05110.1 - 0.0079 16.4 1.1 33 4.7 0.0 3.9 4 0 0 4 4 4 0 RanBP1 domain Kelch_1 PF01344.25 EGB05110.1 - 0.011 15.3 2.9 18 5.0 0.1 4.1 4 0 0 4 4 4 0 Kelch motif HTH_43 PF09904.9 EGB05110.1 - 0.035 14.0 8.9 3.6 7.6 0.1 4.1 4 0 0 4 4 4 0 Winged helix-turn helix Kelch_4 PF13418.6 EGB05110.1 - 0.067 13.2 5.9 13 5.9 0.0 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain baeRF_family5 PF18846.1 EGB05110.1 - 0.12 12.5 7.2 12 6.1 0.1 3.9 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 5 PFU PF09070.11 EGB05110.1 - 0.14 12.4 3.6 40 4.5 0.0 3.9 4 0 0 4 4 4 0 PFU (PLAA family ubiquitin binding) DUF3833 PF12915.7 EGB05110.1 - 0.31 10.6 12.4 14 5.2 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3833) EF-hand_6 PF13405.6 EGB05111.1 - 0.026 14.5 0.0 0.1 12.6 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Iron_traffic PF04362.14 EGB05111.1 - 0.2 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking RNase_HII PF01351.18 EGB05112.1 - 3e-42 144.7 0.0 3.4e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Rhomboid PF01694.22 EGB05113.1 - 5.8e-26 91.3 11.3 6.4e-26 91.1 11.3 1.0 1 0 0 1 1 1 1 Rhomboid family DsbD PF02683.15 EGB05113.1 - 0.0048 16.8 0.5 0.0053 16.7 0.5 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region FAD_binding_3 PF01494.19 EGB05114.1 - 2.9e-08 33.4 0.2 0.0011 18.2 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EGB05114.1 - 0.0002 20.7 0.0 0.00035 19.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGB05114.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB05114.1 - 0.031 14.5 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGB05114.1 - 0.068 11.9 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EGB05114.1 - 0.085 12.4 0.2 0.43 10.1 0.0 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGB05114.1 - 0.087 12.1 0.1 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGB05114.1 - 0.11 11.6 0.8 1.3 8.0 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.14 EGB05114.1 - 0.15 10.9 0.0 7.8 5.2 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Homoserine_dh PF00742.19 EGB05115.1 - 7.6e-41 139.9 0.4 7.6e-41 139.9 0.4 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase AA_kinase PF00696.28 EGB05115.1 - 3.9e-38 131.4 0.1 7.8e-36 123.9 0.0 2.8 2 1 0 2 2 2 1 Amino acid kinase family NAD_binding_3 PF03447.16 EGB05115.1 - 1.7e-12 48.0 0.3 5.9e-12 46.3 0.3 2.0 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 EGB05115.1 - 8.3e-09 35.1 0.7 0.00025 20.7 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EGB05115.1 - 2.1e-08 33.8 3.9 0.0003 20.5 0.2 2.7 2 0 0 2 2 2 2 ACT domain DapB_N PF01113.20 EGB05115.1 - 0.0026 17.9 0.1 0.0097 16.0 0.1 2.0 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EGB05115.1 - 0.021 15.3 0.4 0.021 15.3 0.4 2.8 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain ACT_6 PF13740.6 EGB05115.1 - 0.13 12.3 0.6 2 8.4 0.0 3.1 3 0 0 3 3 3 0 ACT domain Fasciclin PF02469.22 EGB05115.1 - 0.24 11.6 1.7 0.31 11.3 0.2 2.0 3 0 0 3 3 3 0 Fasciclin domain AAA PF00004.29 EGB05117.1 - 2.2e-39 134.9 0.0 3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB05117.1 - 5.5e-08 33.4 0.0 7.5e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_3 PF17862.1 EGB05117.1 - 4.3e-06 26.4 1.5 1.1e-05 25.2 1.5 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB05117.1 - 8.3e-06 25.9 0.0 0.00062 19.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGB05117.1 - 6e-05 23.2 0.0 0.00016 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGB05117.1 - 0.00013 22.1 0.0 0.00028 21.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGB05117.1 - 0.00031 21.1 0.0 0.00044 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EGB05117.1 - 0.00033 20.9 0.0 0.0019 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGB05117.1 - 0.0051 16.2 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGB05117.1 - 0.0055 17.2 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGB05117.1 - 0.0065 16.2 0.0 0.023 14.4 0.0 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGB05117.1 - 0.008 16.4 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGB05117.1 - 0.0094 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 EGB05117.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 EGB05117.1 - 0.019 14.2 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EGB05117.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EGB05117.1 - 0.029 14.1 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGB05117.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.5 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EGB05117.1 - 0.031 13.9 0.1 0.064 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGB05117.1 - 0.064 13.0 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EGB05117.1 - 0.068 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Torsin TsaE PF02367.17 EGB05117.1 - 0.086 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EGB05117.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activat PF00158.26 EGB05117.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 EGB05117.1 - 0.17 11.2 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 EGB05117.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGB05117.1 - 0.23 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EGB05117.1 - 0.26 10.7 0.0 0.42 10.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein WD40 PF00400.32 EGB05118.1 - 3e-124 401.3 55.4 2.7e-10 40.7 0.2 13.0 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05118.1 - 8.2e-38 128.6 13.6 0.003 17.8 0.1 12.2 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB05118.1 - 2.1e-22 79.5 22.6 0.046 12.4 0.2 12.0 4 3 8 12 12 12 9 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGB05118.1 - 5.1e-16 59.0 47.8 0.0019 17.9 5.9 6.0 1 1 4 5 5 5 5 PQQ-like domain Cytochrom_D1 PF02239.16 EGB05118.1 - 2.5e-15 55.9 13.6 0.00016 20.3 0.4 4.8 1 1 4 5 5 5 5 Cytochrome D1 heme domain PQQ PF01011.21 EGB05118.1 - 4.1e-11 42.3 2.3 6.4 6.9 0.0 10.8 12 0 0 12 12 12 1 PQQ enzyme repeat eIF2A PF08662.11 EGB05118.1 - 1.1e-10 41.7 0.2 0.062 13.2 0.0 5.0 2 2 3 6 6 6 3 Eukaryotic translation initiation factor eIF2A BRK PF07533.16 EGB05118.1 - 1.6e-08 34.0 0.0 60 3.4 0.0 10.2 12 0 0 12 12 12 0 BRK domain PALB2_WD40 PF16756.5 EGB05118.1 - 4.3e-07 29.2 35.7 0.093 11.6 0.7 10.4 3 3 9 12 12 12 3 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 EGB05118.1 - 2.4e-06 27.1 0.0 2.7 7.2 0.0 5.6 3 3 4 7 7 7 1 WD40-like domain Cuticle_4 PF15955.5 EGB05118.1 - 3.7e-06 27.6 5.7 43 4.9 0.1 7.9 8 2 0 8 8 7 0 Cuticle protein Surfac_D-trimer PF09006.11 EGB05118.1 - 5.9e-06 26.1 13.8 1.1e+02 2.9 0.0 11.2 12 0 0 12 12 12 0 Lung surfactant protein D coiled-coil trimerisation FlaG PF03646.15 EGB05118.1 - 1.2e-05 25.4 7.3 69 3.7 0.0 10.1 12 0 0 12 12 12 0 FlaG protein Ge1_WD40 PF16529.5 EGB05118.1 - 1.7e-05 24.0 17.5 2.5 7.0 1.2 9.0 2 2 5 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1652 PF07865.11 EGB05118.1 - 2.4e-05 24.1 4.1 28 4.6 0.0 9.3 11 1 1 12 12 12 0 Protein of unknown function (DUF1652) Frtz PF11768.8 EGB05118.1 - 0.00027 19.4 0.0 2.6 6.3 0.0 4.2 3 3 3 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 EGB05118.1 - 0.0004 20.3 4.7 1e+02 3.0 0.0 7.7 9 1 1 10 10 10 0 WD domain, G-beta repeat TruB_C PF09142.11 EGB05118.1 - 0.0028 17.4 26.3 12 5.8 0.1 9.8 7 3 2 10 10 10 0 tRNA Pseudouridine synthase II, C terminal Nucleoporin_N PF08801.11 EGB05118.1 - 0.01 14.6 0.1 8 5.1 0.0 4.5 3 3 1 4 4 4 0 Nup133 N terminal like CNH PF00780.22 EGB05118.1 - 0.014 15.0 0.0 1.4e+02 1.9 0.0 6.3 7 2 3 10 10 9 0 CNH domain WXG100 PF06013.12 EGB05118.1 - 0.059 13.6 0.0 74 3.7 0.0 4.9 7 0 0 7 7 5 0 Proteins of 100 residues with WXG TrfA PF07042.11 EGB05118.1 - 0.098 11.7 6.3 12 4.8 0.0 6.0 4 3 5 9 9 9 0 TrfA protein DUF5570 PF17731.1 EGB05118.1 - 0.1 12.7 52.8 0.27 11.3 0.7 9.4 1 1 11 12 12 12 0 Family of unknown function (DUF5570) DUF769 PF05590.11 EGB05118.1 - 0.12 11.8 1.7 5 6.5 0.0 3.9 2 2 3 5 5 5 0 Xylella fastidiosa protein of unknown function (DUF769) CbiG_N PF11760.8 EGB05118.1 - 0.81 9.7 36.8 17 5.5 0.3 9.9 5 2 6 11 11 11 0 Cobalamin synthesis G N-terminal PQQ_3 PF13570.6 EGB05118.1 - 3 8.5 52.7 8.8 7.0 0.1 11.9 13 0 0 13 13 13 0 PQQ-like domain PAS_9 PF13426.7 EGB05119.1 - 6.5e-08 32.8 0.0 6.7e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EGB05119.1 - 0.037 14.3 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 EGB05119.1 - 0.038 14.0 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 PAS fold FG-GAP_2 PF14312.6 EGB05120.1 - 2.1e-23 82.3 80.4 1.9e-06 28.0 2.3 12.0 11 1 0 11 11 11 7 FG-GAP repeat BNR_2 PF13088.6 EGB05120.1 - 0.0005 19.4 0.0 0.024 13.9 0.0 2.4 2 0 0 2 2 2 1 BNR repeat-like domain BNR_3 PF13859.6 EGB05120.1 - 0.018 14.3 0.1 9.3 5.4 0.1 3.1 2 1 0 2 2 2 0 BNR repeat-like domain BNR PF02012.20 EGB05120.1 - 0.04 13.9 7.4 26 5.3 0.1 4.6 4 0 0 4 4 4 0 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EGB05120.1 - 0.26 10.0 0.2 47 2.6 0.0 3.2 4 0 0 4 4 4 0 Sortilin, neurotensin receptor 3, PQQ_2 PF13360.6 EGB05120.1 - 3.7 7.1 15.0 1.7 8.2 2.4 3.4 1 1 2 3 3 3 0 PQQ-like domain YjeF_N PF03853.15 EGB05122.1 - 1.3e-34 119.6 0.0 1.5e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ysc84 PF04366.12 EGB05123.1 - 3.3e-34 117.4 0.5 4.7e-34 116.9 0.5 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator FIST_C PF10442.9 EGB05124.1 - 2.5e-14 53.4 0.1 4.5e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 FIST C domain FIST PF08495.10 EGB05124.1 - 3.8e-10 40.1 3.6 1.8e-09 37.8 1.5 2.5 2 1 0 2 2 2 1 FIST N domain Arm PF00514.23 EGB05125.1 - 4.4e-34 115.5 10.6 1.6e-10 40.6 0.2 5.7 5 1 0 5 5 5 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EGB05125.1 - 3.6e-06 26.9 0.4 0.0013 18.7 0.0 2.7 2 1 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EGB05125.1 - 0.0016 18.9 15.2 0.035 14.6 0.4 3.9 4 2 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 EGB05125.1 - 0.021 15.2 12.7 0.21 12.0 1.0 3.7 1 1 2 3 3 3 0 HEAT repeats HEAT PF02985.22 EGB05125.1 - 0.033 14.5 3.6 20 5.8 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat KAP PF05804.12 EGB05125.1 - 0.038 12.1 0.0 0.12 10.6 0.0 1.8 2 1 0 2 2 2 0 Kinesin-associated protein (KAP) DUF383 PF04063.14 EGB05125.1 - 0.11 12.1 0.0 7.6 6.1 0.0 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF383) Lipocalin_2 PF08212.12 EGB05125.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like domain UQ_con PF00179.26 EGB05126.1 - 2.3e-39 134.2 0.0 2.6e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA_12 PF13087.6 EGB05127.1 - 1.3e-07 31.4 0.0 3.6e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB05127.1 - 0.0012 19.2 0.0 0.0064 16.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain ACPS PF01648.20 EGB05128.1 - 5.3e-13 49.1 0.0 7.3e-13 48.6 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Metallophos PF00149.28 EGB05129.1 - 4.6e-30 105.7 0.2 6.4e-30 105.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGB05129.1 - 7.2e-28 96.7 0.0 1.3e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 EGB05129.1 - 3.2e-11 42.5 3.3 3.8e-06 26.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05129.1 - 2.3e-09 36.6 4.6 0.00017 21.5 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05129.1 - 1.8e-07 30.9 0.9 0.0053 16.9 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05129.1 - 3.6e-07 29.8 0.1 0.00069 19.2 0.1 2.8 1 1 1 2 2 2 2 TPR repeat TPR_9 PF13371.6 EGB05129.1 - 3.2e-06 27.2 0.2 7.9e-06 25.9 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB05129.1 - 0.0031 18.2 1.8 0.014 16.2 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05129.1 - 0.0036 17.9 0.9 0.0036 17.9 0.9 3.0 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05129.1 - 0.013 15.9 0.3 0.073 13.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB05129.1 - 0.021 15.1 0.2 0.069 13.5 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB05129.1 - 0.027 14.5 0.4 1.1 9.4 0.1 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EGB05129.1 - 0.23 12.2 0.8 0.8 10.5 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Tub PF01167.18 EGB05130.1 - 9.1e-61 205.7 0.0 1.2e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Tub family Gly_transf_sug PF04488.15 EGB05130.1 - 2.4e-07 31.3 0.0 5.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3527 PF12043.8 EGB05130.1 - 0.0032 17.1 0.0 0.061 12.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) NGP1NT PF08153.12 EGB05133.1 - 8.6e-34 116.5 0.0 1.2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGB05133.1 - 8.6e-17 61.3 0.0 1.1e-13 51.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB05133.1 - 6.7e-06 25.8 0.0 0.029 13.9 0.0 3.1 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGB05133.1 - 2e-05 24.2 0.5 0.00015 21.3 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGB05133.1 - 0.0004 20.3 0.0 0.001 19.0 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EGB05133.1 - 0.0015 18.0 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 EGB05133.1 - 0.043 13.9 0.3 2 8.4 0.0 2.6 2 1 1 3 3 3 0 Dynamin family cobW PF02492.19 EGB05133.1 - 0.15 11.7 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EGB05133.1 - 0.16 12.2 0.1 12 6.1 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RRM_1 PF00076.22 EGB05134.1 - 5.3e-57 189.5 0.0 4.5e-15 55.2 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB05134.1 - 1e-08 34.9 0.0 0.0026 17.6 0.0 3.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EGB05134.1 - 0.00015 21.8 0.0 4 7.6 0.0 4.1 4 0 0 4 4 4 1 RNA recognition motif PHM7_cyt PF14703.6 EGB05134.1 - 0.0003 21.1 0.1 1.5 9.0 0.0 4.5 3 2 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 EGB05134.1 - 0.00059 19.7 0.0 1.7 8.7 0.0 3.0 3 0 0 3 3 3 2 RL domain RRM_Rrp7 PF17799.1 EGB05134.1 - 0.00069 19.4 0.0 11 5.8 0.0 3.6 3 1 0 3 3 3 2 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 EGB05134.1 - 0.011 15.8 0.3 4.2 7.5 0.0 3.9 4 1 0 4 4 4 0 Limkain b1 RRM_3 PF08777.11 EGB05134.1 - 0.013 15.5 0.1 0.5 10.4 0.0 3.3 4 0 0 4 4 4 0 RNA binding motif Phage_TAC_13 PF16459.5 EGB05134.1 - 0.067 13.6 0.0 17 5.9 0.0 3.1 3 0 0 3 3 3 0 Phage tail assembly chaperone, TAC OB_RNB PF08206.11 EGB05134.1 - 7.2 6.4 6.0 6.8 6.5 0.1 2.7 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.25 EGB05135.1 - 4.2e-69 233.4 0.0 5.3e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) EF-hand_7 PF13499.6 EGB05136.1 - 2.1e-15 56.9 0.5 0.00039 20.8 0.0 6.6 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_6 PF13405.6 EGB05136.1 - 9.4e-13 47.0 7.7 0.0024 17.6 0.2 7.1 7 0 0 7 7 7 3 EF-hand domain EF-hand_1 PF00036.32 EGB05136.1 - 3.3e-08 32.5 2.7 0.0011 18.4 0.6 5.4 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EGB05136.1 - 0.00025 20.8 1.0 1.3 8.9 0.0 5.7 6 1 0 6 6 6 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB05136.1 - 0.0012 18.2 2.1 0.0096 15.4 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_14 PF17959.1 EGB05136.1 - 0.066 13.6 0.2 6.7 7.1 0.0 3.9 4 1 1 5 5 5 0 EF-hand domain DUF5580 PF17743.1 EGB05136.1 - 0.15 10.6 0.1 0.64 8.5 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Ank_2 PF12796.7 EGB05137.1 - 4.9e-18 65.5 4.8 2.8e-08 34.2 0.5 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB05137.1 - 8.2e-12 45.1 10.9 0.0015 18.8 1.7 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB05137.1 - 4.5e-09 35.8 3.6 0.43 11.3 0.1 6.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EGB05137.1 - 2.3e-08 34.4 2.5 5.7e-05 23.6 0.5 4.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB05137.1 - 6.1e-05 23.3 13.0 0.41 11.2 0.3 5.8 6 0 0 6 6 6 2 Ankyrin repeat ACBP PF00887.19 EGB05137.1 - 9.2e-05 22.6 0.0 0.00052 20.2 0.0 2.4 2 0 0 2 2 2 1 Acyl CoA binding protein AAA PF00004.29 EGB05138.1 - 8.2e-38 129.8 0.0 1.3e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB05138.1 - 5.3e-07 29.3 2.1 1.4e-06 28.0 0.7 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 EGB05138.1 - 1.8e-05 24.9 0.0 3.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGB05138.1 - 2.4e-05 24.1 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGB05138.1 - 2.9e-05 24.5 3.4 0.0049 17.3 0.1 3.2 1 1 2 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGB05138.1 - 3.8e-05 23.7 0.3 0.0009 19.3 0.3 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGB05138.1 - 0.00025 21.1 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB05138.1 - 0.00029 21.0 0.1 0.00066 19.9 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EGB05138.1 - 0.00046 20.5 0.2 0.0044 17.3 0.1 2.4 1 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGB05138.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGB05138.1 - 0.0012 18.3 0.1 0.0024 17.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGB05138.1 - 0.0032 16.7 0.1 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 EGB05138.1 - 0.004 16.9 0.1 0.015 15.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB05138.1 - 0.0061 17.1 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGB05138.1 - 0.0065 16.2 0.0 0.035 13.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EGB05138.1 - 0.032 14.5 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.22 EGB05138.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AAA_25 PF13481.6 EGB05138.1 - 0.046 13.3 0.5 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB05138.1 - 0.047 13.6 0.3 0.22 11.4 0.2 2.0 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EGB05138.1 - 0.05 13.6 0.3 0.35 10.9 0.1 2.5 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGB05138.1 - 0.061 13.7 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EGB05138.1 - 0.078 12.5 0.1 0.15 11.6 0.1 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EGB05138.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.7 1 1 0 1 1 1 0 KaiC DUF815 PF05673.13 EGB05138.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 EGB05138.1 - 0.1 12.1 0.5 0.19 11.2 0.5 1.3 1 0 0 1 1 1 0 PhoH-like protein IPT PF01745.16 EGB05138.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Isopentenyl transferase TniB PF05621.11 EGB05138.1 - 0.11 11.9 0.0 2.5 7.5 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein PNTB PF02233.16 EGB05140.1 - 5.1e-154 513.6 27.8 5.1e-154 513.6 27.8 2.6 3 0 0 3 3 3 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EGB05140.1 - 1.3e-60 204.4 4.7 1.3e-60 204.4 4.7 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EGB05140.1 - 1.6e-38 132.1 2.2 5.7e-38 130.3 0.3 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EGB05140.1 - 6.8e-26 90.5 0.8 6.8e-26 90.5 0.8 3.9 4 1 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EGB05140.1 - 0.00036 19.9 0.2 0.0088 15.4 0.1 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.22 EGB05141.1 - 2.3e-17 62.6 0.0 3e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB05141.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif GH3 PF03321.13 EGB05142.1 - 7e-101 338.7 0.0 8e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter zf-HIT PF04438.16 EGB05143.1 - 5e-06 26.3 13.9 8.3e-06 25.6 13.9 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EGB05143.1 - 1.5 9.0 18.3 3.1 8.0 18.3 1.6 1 0 0 1 1 1 0 MYND finger CPSase_L_D2 PF02786.17 EGB05144.1 - 5.8e-105 349.4 0.1 2.2e-77 259.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EGB05144.1 - 1.4e-50 170.4 0.0 2.9e-50 169.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EGB05144.1 - 2.3e-46 158.0 0.0 3e-45 154.3 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EGB05144.1 - 8.5e-36 123.0 0.0 1.7e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 EGB05144.1 - 1.4e-14 54.2 0.3 3.8e-08 33.1 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGB05144.1 - 4.2e-14 52.4 0.1 6.8e-07 29.1 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 EGB05144.1 - 1.7e-13 50.5 0.1 9.5e-10 38.3 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EGB05144.1 - 2.6e-09 37.2 0.0 3.3e-07 30.3 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 MGS PF02142.22 EGB05144.1 - 1.7e-07 31.3 0.0 7.4e-06 26.1 0.0 3.4 4 0 0 4 4 3 1 MGS-like domain ATP-grasp_3 PF02655.14 EGB05144.1 - 3.7e-06 27.1 0.1 0.022 14.8 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp domain TrbH PF07283.11 EGB05144.1 - 0.00041 20.5 0.1 4.3 7.6 0.0 3.4 3 0 0 3 3 3 2 Conjugal transfer protein TrbH GARS_A PF01071.19 EGB05144.1 - 0.0065 16.3 0.1 0.2 11.4 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 EGB05144.1 - 0.018 14.9 0.2 1.7 8.4 0.0 3.3 3 0 0 3 3 3 0 DJ-1/PfpI family ATP-grasp_5 PF13549.6 EGB05144.1 - 0.046 13.2 0.0 5 6.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain IMP2_N PF18590.1 EGB05145.1 - 7.7e-30 103.3 0.1 1e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 EGB05145.1 - 9.1e-05 22.2 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain HATPase_c_3 PF13589.6 EGB05146.1 - 3.4e-08 33.4 0.0 6.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGB05146.1 - 0.0028 18.1 0.0 0.0061 17.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SGT1 PF07093.11 EGB05146.1 - 0.23 9.9 0.8 0.34 9.3 0.8 1.1 1 0 0 1 1 1 0 SGT1 protein GCIP PF13324.6 EGB05146.1 - 0.9 9.1 2.8 1.6 8.3 2.8 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4407 PF14362.6 EGB05146.1 - 3.3 7.0 25.4 4.1 6.7 9.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Na_sulph_symp PF00939.19 EGB05147.1 - 3.7e-45 154.9 13.4 7.2e-45 153.9 13.4 1.4 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EGB05147.1 - 1.7e-27 96.4 19.3 1.7e-27 96.4 19.3 4.2 3 1 1 4 4 4 2 Citrate transporter Cytochrom_B561 PF03188.16 EGB05147.1 - 2.8e-16 59.9 6.5 1.4e-07 31.7 0.7 2.8 2 0 0 2 2 2 2 Eukaryotic cytochrome b561 DOMON PF03351.17 EGB05147.1 - 4.6e-09 36.6 0.0 0.0031 17.7 0.0 2.3 2 0 0 2 2 2 2 DOMON domain SEP PF08059.13 EGB05147.1 - 0.1 13.2 0.0 4 8.1 0.0 2.4 2 0 0 2 2 2 0 SEP domain CD20 PF04103.15 EGB05147.1 - 2.5 8.2 16.1 4.2 7.4 2.2 4.7 4 0 0 4 4 4 0 CD20-like family Bromodomain PF00439.25 EGB05148.1 - 4.8e-40 135.5 0.0 3.1e-11 43.2 0.0 5.2 5 0 0 5 5 5 4 Bromodomain Gp_dh_C PF02800.20 EGB05149.1 - 3.5e-19 69.0 0.0 3.9e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ribosomal_L21e PF01157.18 EGB05150.1 - 2.1e-44 149.5 4.2 3.3e-44 148.9 2.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e ANAPC4 PF12896.7 EGB05151.1 - 1.2e-29 103.3 0.0 1.8e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EGB05151.1 - 1.6e-15 57.2 0.1 4.3e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGB05151.1 - 0.017 16.0 0.2 0.2 12.6 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat GUN4 PF05419.12 EGB05152.1 - 3e-46 157.0 0.1 3.4e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 GUN4-like PHTB1_C PF14728.6 EGB05153.1 - 1.3e-77 261.4 0.0 3.5e-77 260.0 0.0 1.6 1 1 0 1 1 1 1 PTHB1 C-terminus PHTB1_N PF14727.6 EGB05153.1 - 1.1e-56 193.0 0.0 9.4e-53 180.0 0.0 3.2 1 1 1 2 2 2 2 PTHB1 N-terminus NTP_transf_3 PF12804.7 EGB05153.1 - 2e-09 38.0 1.6 4.9e-09 36.7 1.6 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EGB05153.1 - 2.3e-09 37.2 0.0 6.2e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EGB05153.1 - 9e-05 22.1 1.8 0.018 14.8 0.2 3.1 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EGB05153.1 - 0.0032 16.5 0.1 0.0068 15.4 0.1 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EGB05153.1 - 0.047 11.8 0.0 0.083 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EGB05153.1 - 0.49 10.2 4.5 0.34 10.7 1.5 2.3 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Tyrosinase PF00264.20 EGB05154.1 - 1.5e-08 35.2 8.7 0.00016 22.1 0.1 3.5 3 0 0 3 3 3 2 Common central domain of tyrosinase DUF309 PF03745.14 EGB05154.1 - 0.097 12.4 1.0 0.23 11.2 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF309) CAF1C_H4-bd PF12265.8 EGB05156.1 - 3.1e-28 97.8 0.2 1.1e-27 96.1 0.2 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGB05156.1 - 1.9e-22 79.1 22.3 3.2e-05 24.6 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05156.1 - 0.006 16.8 1.8 0.26 11.6 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M14 PF00246.24 EGB05157.1 - 2.3e-14 53.9 0.0 9.9e-14 51.8 0.0 2.0 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EGB05157.1 - 3.4e-10 40.2 0.0 6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EGB05157.1 - 0.036 13.1 0.0 0.091 11.8 0.0 1.7 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family tRNA-synt_1c PF00749.21 EGB05158.1 - 2.3e-94 315.8 0.0 2.9e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain WD40 PF00400.32 EGB05159.1 - 2.1e-16 60.0 25.6 0.00058 20.6 1.1 10.3 11 0 0 11 11 10 4 WD domain, G-beta repeat TPR_2 PF07719.17 EGB05159.1 - 2.6e-11 42.7 22.1 0.00088 19.2 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05159.1 - 1.3e-10 40.7 10.5 8.6e-05 22.2 0.1 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB05159.1 - 3.1e-10 40.2 32.7 0.0056 16.9 5.1 5.9 4 2 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05159.1 - 8.8e-08 31.8 4.1 0.017 15.3 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05159.1 - 3.3e-07 30.8 45.1 0.00018 22.1 9.0 6.4 7 0 0 7 7 4 4 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 EGB05159.1 - 1.3e-06 28.6 0.0 0.15 12.4 0.0 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_7 PF13176.6 EGB05159.1 - 1.8e-05 24.4 8.4 0.73 10.0 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05159.1 - 8.7e-05 22.1 10.3 0.00057 19.5 0.0 4.6 5 0 0 5 5 5 1 TPR repeat TPR_21 PF09976.9 EGB05159.1 - 0.0017 18.1 14.3 0.53 10.0 0.3 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 EGB05159.1 - 0.004 17.0 24.6 0.005 16.7 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB05159.1 - 0.02 15.1 4.6 0.19 12.0 0.1 3.5 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGB05159.1 - 0.092 13.6 42.2 0.24 12.3 0.7 8.7 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB05159.1 - 0.13 12.5 20.2 0.046 13.9 3.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat eIF2A PF08662.11 EGB05159.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A TPR_19 PF14559.6 EGB05159.1 - 6 7.5 29.0 0.14 12.7 5.1 5.9 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05159.1 - 6.6 7.6 12.2 1.5e+02 3.4 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Kinesin PF00225.23 EGB05160.1 - 4.6e-96 321.6 0.0 5.4e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB05160.1 - 4.2e-41 140.3 0.0 5.9e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding RIIa PF02197.17 EGB05160.1 - 0.03 14.0 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit LRR_6 PF13516.6 EGB05161.1 - 0.0098 15.9 0.3 0.13 12.4 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeat 4HBT_3 PF13622.6 EGB05161.1 - 0.074 13.3 0.5 0.2 11.9 0.2 1.8 2 0 0 2 2 2 0 Thioesterase-like superfamily NRBF2 PF08961.10 EGB05162.1 - 0.046 13.3 2.1 0.16 11.6 2.1 2.0 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator KaiA PF07688.12 EGB05162.1 - 3 8.0 8.5 2 8.6 0.1 3.4 3 0 0 3 3 3 0 KaiA C-terminal domain SF-assemblin PF06705.11 EGB05163.1 - 0.0018 17.7 8.6 0.0018 17.7 8.6 3.4 1 1 2 3 3 3 1 SF-assemblin/beta giardin COMP PF11598.8 EGB05163.1 - 0.012 16.1 3.7 0.029 14.9 0.3 3.3 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein IKKbetaNEMObind PF12179.8 EGB05163.1 - 0.11 12.6 2.9 0.13 12.4 0.2 2.7 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Fib_alpha PF08702.10 EGB05163.1 - 0.12 12.5 26.5 0.2 11.8 11.7 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family IQ PF00612.27 EGB05163.1 - 0.13 12.1 0.4 0.31 10.9 0.4 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif NPV_P10 PF05531.12 EGB05163.1 - 1.5 9.4 15.1 25 5.4 0.1 4.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4806 PF16064.5 EGB05163.1 - 2.7 8.4 5.8 1.6 9.1 0.7 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4806) AAA_31 PF13614.6 EGB05163.1 - 4.1 7.3 9.6 2.6 7.9 3.1 2.6 2 1 0 2 2 2 0 AAA domain ACR_tran PF00873.19 EGB05163.1 - 5.8 4.4 8.4 9.7 3.7 8.4 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF2347 PF09804.9 EGB05163.1 - 6.6 6.2 13.2 1.7 8.2 0.6 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Apolipoprotein PF01442.18 EGB05163.1 - 7.6 6.4 35.8 9 6.1 12.6 3.2 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain RPN1_RPN2_N PF17781.1 EGB05165.1 - 9.8e-106 353.6 0.0 1.4e-105 353.1 0.0 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGB05165.1 - 1.5e-26 92.2 0.0 2.9e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGB05165.1 - 3.5e-19 68.2 9.1 0.00037 20.8 0.3 7.0 7 0 0 7 7 7 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGB05165.1 - 4.5e-09 36.6 0.5 7.9e-05 23.0 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EGB05165.1 - 0.044 14.3 0.1 3.1 8.4 0.1 3.6 2 1 1 3 3 3 0 HEAT-like repeat HEAT PF02985.22 EGB05165.1 - 0.06 13.6 0.9 7.9 7.0 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Pkinase PF00069.25 EGB05166.1 - 1.7e-60 204.6 0.0 2.2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05166.1 - 7.5e-32 110.6 0.0 9.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05166.1 - 6e-05 22.5 0.0 0.00029 20.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 EGB05166.1 - 1 10.1 4.8 2.4 8.9 4.8 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Ribosomal_S24e PF01282.19 EGB05167.1 - 1.7e-32 111.2 0.6 2.5e-32 110.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e Uds1 PF15456.6 EGB05168.1 - 0.072 13.3 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Up-regulated During Septation PEP-utilisers_N PF05524.13 EGB05168.1 - 0.077 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal LRR_4 PF12799.7 EGB05169.1 - 3.8e-20 71.6 15.6 1.9e-06 28.1 1.1 5.0 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB05169.1 - 5.4e-20 71.6 6.1 4.5e-15 55.6 0.9 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EGB05169.1 - 1e-14 54.0 18.6 2.6e-05 23.9 4.8 5.6 4 1 2 6 6 6 4 Leucine rich repeat MCU PF04678.13 EGB05169.1 - 0.073 13.2 1.8 0.18 11.9 1.8 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter LRR_6 PF13516.6 EGB05169.1 - 0.88 9.8 8.4 5 7.4 0.1 4.8 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 EGB05169.1 - 6.9 7.6 15.7 62 4.7 0.8 6.6 6 2 0 6 6 6 0 Leucine Rich Repeat TPR_2 PF07719.17 EGB05170.1 - 1.3e-15 56.1 9.3 0.0015 18.5 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05170.1 - 2.8e-12 45.9 10.0 3.7e-05 23.4 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB05170.1 - 4.6e-12 46.3 5.8 0.0027 18.2 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB05170.1 - 2.7e-10 40.4 8.9 0.036 14.3 0.0 5.2 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05170.1 - 6.4e-10 38.4 0.4 1.6 9.1 0.0 5.7 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05170.1 - 2e-09 37.9 1.4 2.7 8.7 0.0 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB05170.1 - 3.1e-09 36.9 3.4 0.3 12.0 0.0 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05170.1 - 1.7e-05 24.4 5.2 0.0062 16.2 0.1 4.9 5 1 1 6 6 6 1 TPR repeat ANAPC3 PF12895.7 EGB05170.1 - 3.8e-05 23.8 8.9 0.11 12.8 0.1 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGB05170.1 - 0.00033 20.8 1.6 16 5.7 0.0 4.4 2 2 2 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05170.1 - 0.0024 18.1 5.7 0.71 10.4 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05170.1 - 0.0035 17.9 4.4 8.5 7.3 0.1 5.6 8 0 0 8 8 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05170.1 - 0.0094 15.9 9.2 2.5 8.3 0.0 5.7 5 2 1 6 6 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGB05170.1 - 0.071 13.1 0.4 1.9 8.5 0.1 2.8 2 1 1 3 3 3 0 Putative TPR-like repeat TPR_10 PF13374.6 EGB05170.1 - 3 7.8 9.1 39 4.3 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MORN PF02493.20 EGB05172.1 - 3e-55 180.9 78.7 4.6e-07 29.4 2.6 13.7 14 0 0 14 14 14 13 MORN repeat EIF_2_alpha PF07541.12 EGB05173.1 - 1.1e-38 131.9 0.1 2e-38 131.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGB05173.1 - 1.7e-12 47.5 0.2 2.8e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 S1 RNA binding domain EcKinase PF02958.20 EGB05173.1 - 0.064 12.6 1.0 0.13 11.5 0.1 1.9 3 0 0 3 3 3 0 Ecdysteroid kinase Cmc1 PF08583.10 EGB05173.1 - 0.067 13.2 0.6 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nic96 PF04097.14 EGB05174.1 - 0.28 9.6 1.6 0.38 9.2 1.6 1.1 1 0 0 1 1 1 0 Nup93/Nic96 Spore_III_AF PF09581.10 EGB05174.1 - 0.37 10.8 1.8 0.56 10.2 1.8 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) RR_TM4-6 PF06459.12 EGB05174.1 - 1.5 8.5 5.1 2.3 8.0 5.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAE1_CUT1_RppA PF08392.12 EGB05175.1 - 6e-95 317.9 0.3 1.3e-88 297.1 0.0 2.1 1 1 1 2 2 2 2 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 EGB05175.1 - 4.3e-13 49.5 0.0 8.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 EGB05175.1 - 3.5e-11 43.1 0.0 9.7e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGB05175.1 - 1.6e-05 24.7 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DEAD PF00270.29 EGB05176.1 - 2e-23 83.1 0.0 1.7e-21 76.8 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB05176.1 - 1.5e-20 73.6 0.0 3.7e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EGB05176.1 - 4.2e-11 42.9 2.1 9.2e-11 41.8 2.1 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RRM_1 PF00076.22 EGB05176.1 - 3.5e-09 36.3 0.0 0.00093 19.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MCM PF00493.23 EGB05177.1 - 6.3e-90 300.2 0.2 1.4e-89 299.0 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGB05177.1 - 1.7e-32 111.9 0.0 4.6e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGB05177.1 - 1.4e-21 76.7 0.4 2.7e-21 75.8 0.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGB05177.1 - 2.7e-12 47.2 0.1 5.9e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGB05177.1 - 1.3e-07 31.2 0.2 1.5e-06 27.7 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGB05177.1 - 0.0018 18.1 0.0 0.0048 16.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGB05177.1 - 0.017 14.8 0.1 0.047 13.4 0.1 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 EGB05177.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sulfatase PF00884.23 EGB05178.1 - 1.9e-36 126.0 0.0 2.6e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Tho2 PF11262.8 EGB05179.1 - 8.5e-68 228.7 2.6 1.4e-66 224.8 2.6 2.2 1 1 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 EGB05179.1 - 5e-43 147.7 0.0 2e-27 96.1 0.0 3.2 2 1 0 2 2 2 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 EGB05179.1 - 2.1e-27 95.0 0.0 4.6e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Sel1 PF08238.12 EGB05179.1 - 0.0098 16.6 0.2 0.034 14.8 0.2 2.0 1 0 0 1 1 1 1 Sel1 repeat CENP-B_N PF04218.13 EGB05179.1 - 0.051 13.2 1.1 0.49 10.1 0.1 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Seryl_tRNA_N PF02403.22 EGB05179.1 - 0.098 12.9 0.9 0.36 11.1 0.9 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Aminotran_5 PF00266.19 EGB05181.1 - 7.5e-31 107.4 0.0 1.1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 EGB05181.1 - 7e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Aminotran_1_2 PF00155.21 EGB05181.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_transf_41 PF13844.6 EGB05183.1 - 6.5e-93 311.7 0.0 4.7e-53 180.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 EGB05183.1 - 9.7e-84 274.8 21.3 4.5e-13 48.7 0.9 12.1 2 2 10 12 12 12 11 TPR repeat TPR_1 PF00515.28 EGB05183.1 - 1.6e-77 252.4 25.9 8.9e-09 34.8 0.1 14.4 13 1 0 13 13 13 11 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05183.1 - 5.5e-64 207.2 26.0 8.2e-07 28.7 0.3 13.1 12 1 0 12 12 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05183.1 - 2e-55 181.3 23.8 1.1e-06 28.5 0.1 12.7 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05183.1 - 3.4e-50 164.1 10.6 0.00042 20.3 0.0 12.8 12 2 0 12 12 11 10 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05183.1 - 8.8e-44 147.9 19.0 4.2e-08 33.7 0.1 8.6 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05183.1 - 1.5e-40 134.2 13.2 0.00052 19.8 0.5 12.6 11 1 1 12 12 12 8 Tetratricopeptide repeat TPR_14 PF13428.6 EGB05183.1 - 1.1e-37 125.4 22.2 3.6e-06 27.3 0.7 11.7 4 2 8 12 12 11 9 Tetratricopeptide repeat TPR_12 PF13424.6 EGB05183.1 - 2.3e-31 107.9 36.1 1.8e-06 28.1 0.2 9.1 5 4 2 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGB05183.1 - 1.4e-25 89.6 26.8 0.00024 21.5 0.0 9.4 4 2 2 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 EGB05183.1 - 1.9e-23 81.6 49.3 0.00065 19.5 0.1 12.3 10 1 2 12 12 12 7 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05183.1 - 4.1e-15 55.3 14.0 0.27 12.0 0.0 9.8 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB05183.1 - 1.3e-11 44.4 23.1 0.0039 17.3 0.2 7.8 3 2 6 9 9 9 3 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 EGB05183.1 - 7.7e-10 38.7 15.3 0.0026 17.3 0.1 6.2 6 2 1 7 7 7 3 Est1 DNA/RNA binding domain TPR_4 PF07721.14 EGB05183.1 - 6.3e-08 32.5 30.1 0.054 14.1 1.8 9.3 9 0 0 9 9 8 2 Tetratricopeptide repeat FAT PF02259.23 EGB05183.1 - 8.8e-07 28.5 0.0 0.27 10.4 0.0 4.5 1 1 3 5 5 5 2 FAT domain TPR_15 PF13429.6 EGB05183.1 - 1.4e-06 27.7 3.0 5 6.2 0.1 6.0 2 1 3 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 EGB05183.1 - 1.2e-05 24.5 0.3 2.5 6.9 0.0 4.3 3 2 0 4 4 4 1 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 EGB05183.1 - 5.5e-05 22.7 13.5 0.026 13.9 0.9 5.0 1 1 2 5 5 5 3 MalT-like TPR region SNAP PF14938.6 EGB05183.1 - 0.0011 18.5 11.1 1.2 8.5 1.7 5.8 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP BTAD PF03704.17 EGB05183.1 - 0.0014 19.0 15.1 0.017 15.5 0.0 5.0 3 1 3 6 6 5 1 Bacterial transcriptional activator domain TPR_21 PF09976.9 EGB05183.1 - 0.0026 17.5 1.5 8 6.1 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 EGB05183.1 - 0.0028 17.6 0.6 15 5.7 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGB05183.1 - 0.0033 16.9 0.0 3.5 7.1 0.0 4.3 5 0 0 5 5 4 1 SHNi-TPR PPR PF01535.20 EGB05183.1 - 0.0036 17.5 2.3 13 6.3 0.0 5.6 6 0 0 6 6 5 0 PPR repeat TOM20_plant PF06552.12 EGB05183.1 - 0.013 15.2 0.1 30 4.3 0.0 4.8 4 1 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 EGB05183.1 - 0.054 13.6 1.7 15 5.8 0.1 4.9 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EGB05183.1 - 0.057 13.5 20.1 5.4 7.2 0.3 7.4 6 2 1 7 7 7 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EGB05183.1 - 0.085 13.1 10.3 4.6 7.5 0.2 4.8 3 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 EGB05183.1 - 0.31 11.0 4.3 29 4.7 0.1 4.0 4 2 1 5 5 5 0 Mad3/BUB1 homology region 1 DUF4810 PF16068.5 EGB05183.1 - 0.39 11.3 1.2 69 4.1 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4810) Ras PF00071.22 EGB05184.1 - 5.8e-49 165.8 0.0 9.1e-48 161.9 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGB05184.1 - 4.4e-34 117.3 0.0 7.1e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB05184.1 - 2.4e-15 56.4 0.0 2.8e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB05184.1 - 0.0023 18.0 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB05184.1 - 0.0096 15.5 0.0 0.07 12.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB05184.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AIRC PF00731.20 EGB05184.1 - 0.051 13.1 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 AIR carboxylase MCM PF00493.23 EGB05185.1 - 3.3e-88 294.5 0.0 5.1e-88 293.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGB05185.1 - 6.7e-31 106.8 0.2 1.6e-30 105.6 0.1 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EGB05185.1 - 3e-23 82.1 1.7 3.9e-23 81.7 0.3 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGB05185.1 - 2e-07 30.6 0.0 4.4e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 EGB05185.1 - 2.6e-05 24.7 0.0 6.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 EGB05185.1 - 0.0022 17.8 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGB05185.1 - 0.013 15.3 0.1 0.036 13.8 0.0 1.7 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EGB05185.1 - 0.025 14.6 0.0 0.14 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Nore1-SARAH PF16517.5 EGB05185.1 - 0.17 11.8 0.4 0.35 10.8 0.4 1.5 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Pkinase PF00069.25 EGB05186.1 - 2.1e-63 214.2 0.0 3.7e-63 213.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05186.1 - 8e-32 110.5 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGB05186.1 - 4.1e-19 66.6 0.2 4.1e-06 26.0 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGB05186.1 - 7.1e-16 58.4 4.8 3.4e-07 30.6 1.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EGB05186.1 - 1.8e-14 53.3 4.0 2.2e-05 24.2 0.2 4.4 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGB05186.1 - 1.2e-13 49.8 1.0 0.00041 20.0 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGB05186.1 - 3.7e-09 35.7 4.1 0.00032 20.0 0.0 4.3 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 EGB05186.1 - 2.6e-05 24.5 0.4 0.28 11.5 0.0 2.7 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 EGB05186.1 - 0.0016 18.4 0.2 0.0044 17.0 0.2 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB05186.1 - 0.0017 17.7 2.1 0.029 13.7 0.7 2.8 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_11 PF08976.11 EGB05186.1 - 0.0077 17.1 0.3 0.23 12.3 0.0 2.5 1 1 0 2 2 2 1 EF-hand domain Kinase-like PF14531.6 EGB05186.1 - 0.011 15.1 0.1 0.059 12.7 0.1 2.1 1 1 0 1 1 1 0 Kinase-like EF-hand_9 PF14658.6 EGB05186.1 - 0.019 15.3 0.1 11 6.4 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 EGB05186.1 - 0.076 13.0 1.9 6.5 6.8 0.3 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand FTA2 PF13095.6 EGB05186.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RtcB PF01139.17 EGB05188.1 - 1.2e-146 489.1 0.0 1.4e-146 488.9 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Ubiq-assoc PF09145.10 EGB05188.1 - 0.18 11.8 1.2 0.46 10.5 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin-associated MCM PF00493.23 EGB05189.1 - 8.4e-90 299.8 0.0 1.3e-89 299.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGB05189.1 - 1.7e-29 102.2 0.1 3.1e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGB05189.1 - 1.8e-23 82.8 0.1 5.2e-23 81.3 0.1 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 EGB05189.1 - 5.8e-09 36.1 0.0 1.5e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 EGB05189.1 - 6.7e-09 36.3 0.2 2.1e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGB05189.1 - 6.2e-08 32.3 0.3 0.00045 19.7 0.0 3.1 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 EGB05189.1 - 2.5e-07 31.1 18.6 5.4e-07 30.0 16.6 2.5 2 1 0 2 2 2 1 Mini-chromosome maintenance protein 2 AAA_3 PF07726.11 EGB05189.1 - 0.016 15.1 0.0 0.052 13.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EGB05189.1 - 0.042 13.7 0.2 0.042 13.7 0.2 2.1 2 0 0 2 2 2 0 AAA lid domain PhoU_div PF01865.16 EGB05189.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF47 Cpn60_TCP1 PF00118.24 EGB05190.1 - 5.1e-142 473.9 8.8 5.9e-142 473.8 8.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RCC1 PF00415.18 EGB05193.1 - 1.2e-26 93.1 2.5 1.6e-13 51.0 0.0 2.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB05193.1 - 6e-13 48.2 3.1 0.001 18.8 0.1 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat 7kD_DNA_binding PF02294.18 EGB05193.1 - 0.12 12.5 0.0 3.3 7.8 0.0 2.1 2 0 0 2 2 2 0 7kD DNA-binding domain HECT PF00632.25 EGB05194.1 - 4.5e-50 170.9 0.0 6.2e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WD40 PF00400.32 EGB05195.1 - 1.3e-60 199.9 20.2 6.4e-09 36.3 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05195.1 - 4.5e-19 68.5 2.2 5.5e-05 23.4 0.0 6.7 2 1 6 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Motile_Sperm PF00635.26 EGB05195.1 - 7.5e-10 38.6 0.1 1.7e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain WD40_like PF17005.5 EGB05195.1 - 4.8e-09 36.0 1.8 0.00056 19.3 0.3 5.0 3 2 2 5 5 5 2 WD40-like domain Nup160 PF11715.8 EGB05195.1 - 4.9e-08 32.1 5.9 0.12 11.0 0.0 4.9 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGB05195.1 - 3.6e-05 22.9 4.4 0.016 14.2 1.1 4.1 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 EGB05195.1 - 0.014 15.4 0.2 2 8.5 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF5570 PF17731.1 EGB05195.1 - 0.072 13.2 6.4 11 6.1 0.0 4.1 1 1 3 5 5 4 0 Family of unknown function (DUF5570) PKD PF00801.20 EGB05195.1 - 0.15 12.0 0.2 35 4.3 0.1 3.2 3 0 0 3 3 3 0 PKD domain Pyrophosphatase PF00719.19 EGB05198.1 - 1.7e-42 145.0 0.0 2.3e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase ATP-sulfurylase PF01747.17 EGB05198.1 - 6.8e-23 81.3 0.0 1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase Glyco_transf_8C PF08437.10 EGB05198.1 - 0.024 14.7 0.1 0.067 13.3 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal ENTH PF01417.20 EGB05199.1 - 4.3e-23 81.7 0.2 6.4e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGB05199.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 ANTH domain DpnI_C PF17726.1 EGB05199.1 - 0.18 12.0 0.3 0.34 11.1 0.3 1.4 1 0 0 1 1 1 0 Dam-replacing HTH domain PspA_IM30 PF04012.12 EGB05200.1 - 0.0011 18.6 7.5 0.0014 18.2 7.5 1.1 1 0 0 1 1 1 1 PspA/IM30 family DUF601 PF04642.12 EGB05200.1 - 0.19 11.2 5.1 5.2 6.5 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF601 TPR_1 PF00515.28 EGB05201.1 - 2.5e-25 87.2 10.2 3.4e-07 29.8 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05201.1 - 2e-24 83.7 16.2 1.4e-05 24.8 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05201.1 - 2.6e-16 58.4 1.5 0.021 15.0 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGB05201.1 - 3e-15 55.6 12.6 3.1e-05 24.4 0.1 7.5 6 3 3 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB05201.1 - 4.8e-13 49.4 5.1 0.0033 17.9 0.5 5.9 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05201.1 - 5.2e-13 49.4 4.5 0.00073 20.1 0.0 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGB05201.1 - 3.9e-12 46.3 17.7 0.009 16.3 0.0 7.0 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGB05201.1 - 1e-10 41.6 3.6 0.03 14.4 0.1 4.9 3 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05201.1 - 6.1e-08 32.2 3.6 0.0043 16.7 0.0 6.1 6 1 1 7 7 7 1 TPR repeat TPR_17 PF13431.6 EGB05201.1 - 1.7e-06 28.0 4.7 3.8 8.1 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05201.1 - 0.00032 20.5 8.0 0.056 13.5 0.0 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EGB05201.1 - 0.00051 20.0 0.4 1.2 9.3 0.1 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 EGB05201.1 - 0.0011 19.5 10.7 0.071 13.8 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB05201.1 - 0.002 18.3 16.6 0.072 13.3 1.1 5.4 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGB05201.1 - 0.042 13.1 3.8 0.059 12.6 0.7 2.8 3 1 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EGB05201.1 - 0.062 12.3 0.1 6.4 5.7 0.1 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 EGB05201.1 - 0.09 12.9 16.4 0.2 11.8 0.1 5.4 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Tho2 PF11262.8 EGB05204.1 - 8.2e-77 258.4 0.2 1.1e-76 257.9 0.2 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EGB05204.1 - 2.6e-12 46.6 0.0 1.4e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit ZapB PF06005.12 EGB05204.1 - 0.011 16.2 1.1 0.023 15.1 1.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB CENP-B_N PF04218.13 EGB05204.1 - 0.021 14.5 0.8 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain TACC_C PF05010.14 EGB05204.1 - 0.23 11.3 1.7 0.27 11.0 0.1 1.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TRAPP PF04051.16 EGB05205.1 - 1.9e-26 92.5 0.0 3.5e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.32 EGB05205.1 - 3.5e-11 43.5 12.6 0.00028 21.6 0.2 8.4 9 0 0 9 9 9 2 WD domain, G-beta repeat Syntaxin_2 PF14523.6 EGB05207.1 - 1.4 9.3 7.3 4.1 7.8 7.3 1.9 1 0 0 1 1 1 0 Syntaxin-like protein FapA PF03961.13 EGB05207.1 - 1.7 7.1 11.1 2.4 6.7 0.2 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3772 PF12607.8 EGB05207.1 - 2.9 7.7 7.6 1.1 9.0 1.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) LRR_4 PF12799.7 EGB05208.1 - 5.2e-18 64.9 27.2 3.6e-10 39.9 3.7 4.7 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB05208.1 - 1e-16 61.0 11.0 1.8e-16 60.1 4.0 3.6 2 1 2 4 4 4 2 Leucine-rich repeat LRR_8 PF13855.6 EGB05208.1 - 2.5e-10 40.0 19.3 9.1e-06 25.3 9.1 4.1 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 EGB05208.1 - 1.2 9.3 15.3 1.1 9.5 0.5 4.8 3 1 1 4 4 4 0 Leucine Rich repeat Tyrosinase PF00264.20 EGB05209.1 - 7.1e-09 36.3 0.0 1.6e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase HAT_KAT11 PF08214.11 EGB05210.1 - 1.8e-36 126.2 0.9 1.1e-34 120.3 0.1 2.3 1 1 1 2 2 2 2 Histone acetylation protein Bromodomain PF00439.25 EGB05210.1 - 2.8e-18 65.8 0.0 7.1e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.16 EGB05210.1 - 3.1e-12 46.8 14.3 3.1e-12 46.8 14.3 3.4 3 0 0 3 3 3 1 TAZ zinc finger PHD PF00628.29 EGB05210.1 - 4.5e-05 23.3 4.4 4.5e-05 23.3 4.4 5.2 6 1 0 6 6 6 1 PHD-finger PHD_2 PF13831.6 EGB05210.1 - 0.085 12.4 12.9 0.93 9.1 2.8 3.3 2 0 0 2 2 2 0 PHD-finger DUF902 PF06001.13 EGB05210.1 - 0.57 10.7 6.8 1.9 9.0 6.8 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) ZZ PF00569.17 EGB05210.1 - 1.1 9.2 15.4 1.2 9.0 6.6 3.5 2 0 0 2 2 2 0 Zinc finger, ZZ type DM PF00751.18 EGB05210.1 - 4.7 7.2 18.6 2.2 8.2 4.8 3.6 3 0 0 3 3 3 0 DM DNA binding domain HMGL-like PF00682.19 EGB05211.1 - 1.2e-84 284.0 0.0 2.2e-84 283.2 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EGB05211.1 - 1.2e-29 102.8 1.1 2.4e-29 101.9 1.1 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF374 PF04028.13 EGB05211.1 - 0.0092 15.5 0.1 0.11 12.0 0.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF374) STAT1_TAZ2bind PF12162.8 EGB05211.1 - 0.17 11.5 0.0 0.57 9.8 0.0 1.9 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Kinesin PF00225.23 EGB05212.1 - 1.8e-119 398.6 2.4 5.2e-119 397.1 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGB05212.1 - 1.2e-27 96.7 0.0 6.6e-27 94.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 EGB05212.1 - 0.0047 17.1 14.7 0.02 15.0 14.3 2.3 1 1 0 1 1 1 1 Kinesin-associated DUF812 PF05667.11 EGB05212.1 - 0.079 11.8 31.9 0.12 11.3 31.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NRN1 PF15056.6 EGB05212.1 - 0.13 12.3 0.8 0.44 10.7 0.8 1.9 1 0 0 1 1 1 0 Neuritin protein family Radical_SAM_N PF08497.10 EGB05212.1 - 0.2 10.9 4.4 0.36 10.0 4.4 1.5 1 0 0 1 1 1 0 Radical SAM N-terminal PrmA PF06325.13 EGB05213.1 - 1e-05 25.1 1.4 4.7e-05 22.9 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EGB05213.1 - 0.00013 21.8 0.1 0.0053 16.5 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EGB05213.1 - 0.00014 22.5 1.7 0.0078 16.9 0.2 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGB05213.1 - 0.00036 20.5 0.0 0.0039 17.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB05213.1 - 0.0025 17.5 0.0 0.036 13.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 EGB05213.1 - 0.0061 17.6 0.2 0.16 13.0 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB05213.1 - 0.0081 16.0 0.0 0.059 13.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGB05213.1 - 0.011 15.3 1.0 0.036 13.6 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EGB05213.1 - 0.021 14.6 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 EGB05213.1 - 0.047 13.4 0.2 4.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_11 PF08241.12 EGB05213.1 - 0.067 13.9 2.4 1.3 9.7 0.0 4.0 5 0 0 5 5 5 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB05213.1 - 0.091 13.5 0.2 1 10.1 0.0 3.0 4 1 0 4 4 3 0 Methyltransferase domain RrnaAD PF00398.20 EGB05213.1 - 0.21 10.6 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase RCC1 PF00415.18 EGB05214.1 - 3.5e-21 75.6 5.5 3e-05 24.5 1.9 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat TIG PF01833.24 EGB05214.1 - 6.6e-08 32.5 0.0 0.49 10.5 0.0 5.9 5 1 0 5 5 5 2 IPT/TIG domain RCC1_2 PF13540.6 EGB05214.1 - 0.00015 21.5 11.4 1.2 9.0 0.1 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat HTH_Tnp_IS1 PF12759.7 EGB05215.1 - 0.038 13.6 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 InsA C-terminal domain Ras PF00071.22 EGB05216.1 - 2.7e-59 199.4 0.1 3.4e-59 199.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB05216.1 - 3.5e-32 111.1 0.0 5.6e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB05216.1 - 8.6e-13 48.1 0.0 1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB05216.1 - 3.3e-05 23.9 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB05216.1 - 0.00037 20.4 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGB05216.1 - 0.0039 16.7 0.1 0.022 14.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB05216.1 - 0.007 15.7 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGB05216.1 - 0.0071 16.6 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain DAP3 PF10236.9 EGB05216.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TetR_C_16 PF17920.1 EGB05216.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF202 PF02656.15 EGB05217.1 - 1.6e-13 50.9 9.7 3.1e-13 50.0 8.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ER_lumen_recept PF00810.18 EGB05218.1 - 6.1e-49 166.6 10.1 1.1e-48 165.8 10.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGB05218.1 - 0.12 12.1 10.2 0.21 11.4 0.2 3.8 4 1 1 5 5 5 0 PQ loop repeat FANCI_S3 PF14677.6 EGB05220.1 - 0.021 14.5 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 FANCI solenoid 3 PAS_9 PF13426.7 EGB05221.1 - 2e-12 47.3 0.0 2.1e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EGB05221.1 - 0.00032 20.9 0.0 0.00039 20.6 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EGB05221.1 - 0.039 14.0 0.0 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 PAS fold ECR1_N PF14382.6 EGB05221.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region PAS_3 PF08447.12 EGB05221.1 - 0.14 12.4 0.0 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 PAS fold Ribosomal_S13_N PF08069.12 EGB05222.1 - 5e-30 103.3 0.3 1e-29 102.3 0.3 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGB05222.1 - 1e-12 48.1 2.2 1.5e-12 47.5 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Put_DNA-bind_N PF06971.13 EGB05222.1 - 0.1 12.6 0.5 0.33 11.0 0.3 2.0 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus S1 PF00575.23 EGB05223.1 - 9.3e-31 106.0 0.7 6.5e-17 61.6 0.0 3.4 3 0 0 3 3 3 3 S1 RNA binding domain FlgT_N PF16548.5 EGB05223.1 - 0.11 13.0 0.2 13 6.4 0.1 2.5 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain HAUS-augmin3 PF14932.6 EGB05224.1 - 0.16 11.5 21.5 0.14 11.7 8.1 3.2 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 DUF4599 PF15371.6 EGB05224.1 - 0.33 11.5 6.6 0.16 12.5 2.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4599) Cas_DxTHG PF09455.10 EGB05224.1 - 2.3 7.7 6.1 3.8 7.0 0.1 2.3 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family DUF3924 PF13062.6 EGB05225.1 - 0.047 13.6 1.4 3.2 7.8 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) Peptidase_S9 PF00326.21 EGB05226.1 - 0.00016 21.2 0.0 0.0008 18.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGB05226.1 - 0.00041 19.7 0.0 0.41 9.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF818 PF05677.12 EGB05226.1 - 0.0043 16.0 0.0 0.0094 14.9 0.0 1.6 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 EGB05226.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF126 PF01989.16 EGB05226.1 - 0.045 13.5 0.1 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Aconitase X swivel domain Abhydrolase_1 PF00561.20 EGB05226.1 - 0.075 12.7 0.0 0.36 10.4 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Asp2 PF16929.5 EGB05226.1 - 0.088 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter PBP_like PF12727.7 EGB05226.1 - 0.14 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 PBP superfamily domain Pkinase PF00069.25 EGB05227.1 - 3.4e-52 177.4 0.0 3.9e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05227.1 - 2e-27 96.1 0.0 2.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05227.1 - 0.0071 16.3 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EGB05227.1 - 0.028 13.4 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 EGB05227.1 - 0.059 12.3 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DASH_Dam1 PF08653.10 EGB05227.1 - 0.085 12.7 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 Kinase-like PF14531.6 EGB05227.1 - 0.085 12.2 0.1 0.22 10.8 0.0 1.7 2 1 0 2 2 2 0 Kinase-like Pkinase PF00069.25 EGB05228.1 - 2e-61 207.7 0.0 2.3e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05228.1 - 8.8e-29 100.6 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05228.1 - 0.00049 19.5 0.0 0.00099 18.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB05228.1 - 0.0047 16.9 0.0 0.021 14.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB05228.1 - 0.019 14.3 0.7 0.028 13.8 0.7 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGB05228.1 - 0.04 13.5 0.2 0.065 12.8 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EGB05228.1 - 0.053 12.5 0.2 0.069 12.1 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF825 PF05695.12 EGB05228.1 - 0.077 10.1 0.0 0.098 9.8 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) PI3_PI4_kinase PF00454.27 EGB05229.1 - 2.5e-58 197.9 0.1 3.6e-58 197.3 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EGB05229.1 - 4e-25 88.1 1.3 2.7e-23 82.3 0.6 2.5 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FAT PF02259.23 EGB05229.1 - 5.8e-13 48.8 0.0 9.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 EGB05229.1 - 6e-09 35.6 0.4 1.5e-08 34.3 0.4 1.7 1 0 0 1 1 1 1 FATC domain Thioredoxin PF00085.20 EGB05230.1 - 6.2e-19 67.9 0.1 1.3e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin COPIIcoated_ERV PF07970.12 EGB05230.1 - 2.3e-12 47.2 0.4 3.3e-12 46.7 0.4 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin_2 PF13098.6 EGB05230.1 - 0.00064 20.1 0.2 0.0013 19.2 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGB05230.1 - 0.00088 18.7 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGB05230.1 - 0.099 12.8 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like DSPc PF00782.20 EGB05231.1 - 2.8e-16 59.5 0.1 5.9e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB05231.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RRM_occluded PF16842.5 EGB05231.1 - 0.094 12.6 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif TPR_12 PF13424.6 EGB05232.1 - 0.0021 18.3 0.0 0.0075 16.5 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGB05232.1 - 0.0026 17.6 0.1 0.0061 16.4 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 EGB05232.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB05232.1 - 0.052 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 EGB05232.1 - 0.08 13.2 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Pkinase PF00069.25 EGB05233.1 - 7.8e-46 156.6 0.0 4.4e-45 154.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05233.1 - 4.5e-25 88.4 0.0 7.8e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 EGB05233.1 - 0.0081 16.2 0.0 0.028 14.5 0.0 2.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain APH PF01636.23 EGB05233.1 - 0.055 13.4 0.5 1.2 9.0 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EGB05233.1 - 0.064 12.2 0.1 0.099 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DASH_Dam1 PF08653.10 EGB05233.1 - 0.14 11.9 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 Acyl-CoA_dh_2 PF08028.11 EGB05233.1 - 0.15 12.4 1.6 0.41 10.9 1.6 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Haspin_kinase PF12330.8 EGB05233.1 - 0.2 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DHC_N2 PF08393.13 EGB05234.1 - 1.9e-58 198.5 0.0 3.4e-58 197.7 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EGB05234.1 - 7.4e-05 21.9 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 EGB05234.1 - 0.00031 20.8 0.0 0.0011 19.1 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EGB05234.1 - 0.089 13.2 0.7 0.39 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGB05234.1 - 0.11 12.2 0.2 0.3 10.8 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain L27 PF02828.16 EGB05234.1 - 0.12 12.2 0.0 0.47 10.2 0.0 2.1 1 0 0 1 1 1 0 L27 domain AAA_9 PF12781.7 EGB05235.1 - 4.3e-06 26.0 0.0 8.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region CorA PF01544.18 EGB05239.1 - 0.00051 19.5 0.0 0.00085 18.7 0.0 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Fe-ADH PF00465.19 EGB05239.1 - 0.062 12.1 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase HTH_Tnp_Tc3_1 PF11427.8 EGB05240.1 - 0.016 15.1 0.1 0.044 13.6 0.1 1.9 2 0 0 2 2 2 0 Tc3 transposase DUF4763 PF15960.5 EGB05240.1 - 0.048 13.0 0.2 0.059 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DASH_Duo1 PF08651.10 EGB05240.1 - 0.11 12.2 1.3 0.15 11.9 0.4 1.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 Ank_4 PF13637.6 EGB05241.1 - 3.9e-08 33.7 0.5 1.2e-05 25.8 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB05241.1 - 1.1e-07 32.3 2.7 0.0003 21.3 0.3 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB05241.1 - 2.4e-07 30.9 0.2 1.3e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB05241.1 - 7.2e-06 26.2 1.7 0.00059 20.2 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EGB05241.1 - 6e-05 23.1 0.2 0.00058 20.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat DUF3523 PF12037.8 EGB05242.1 - 2.4e-85 286.1 24.0 3.5e-85 285.6 24.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 EGB05242.1 - 4e-22 79.1 0.0 1.1e-21 77.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGB05242.1 - 6.5e-06 26.0 0.0 1.9e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGB05242.1 - 2.4e-05 24.5 0.0 2.4e-05 24.5 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 EGB05242.1 - 0.00016 21.7 1.9 0.0017 18.3 0.1 3.2 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB05242.1 - 0.00034 20.9 5.8 0.016 15.5 0.0 3.3 2 2 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGB05242.1 - 0.0004 20.8 0.0 0.0004 20.8 0.0 3.6 2 2 1 3 3 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EGB05242.1 - 0.00048 19.6 0.1 0.0021 17.5 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGB05242.1 - 0.0042 17.6 0.1 0.03 14.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB05242.1 - 0.006 16.5 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 EGB05242.1 - 0.0092 15.3 0.1 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 EGB05242.1 - 0.0097 15.7 0.0 0.029 14.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EGB05242.1 - 0.0098 15.9 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGB05242.1 - 0.0099 15.7 0.0 0.03 14.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGB05242.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 EGB05242.1 - 0.019 14.5 0.1 0.019 14.5 0.1 3.1 3 2 0 3 3 2 0 AAA domain AAA_lid_3 PF17862.1 EGB05242.1 - 0.027 14.3 0.9 0.09 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA+ lid domain Sigma54_activ_2 PF14532.6 EGB05242.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGB05242.1 - 0.029 14.4 0.0 0.14 12.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB05242.1 - 0.031 13.8 0.0 0.095 12.2 0.0 1.8 1 1 1 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGB05242.1 - 0.036 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zot PF05707.12 EGB05242.1 - 0.05 13.3 0.6 1.3 8.6 0.0 2.8 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EGB05242.1 - 0.083 12.7 0.0 0.083 12.7 0.0 2.7 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EGB05242.1 - 0.11 13.1 0.1 1.1 9.8 0.0 2.6 2 2 0 2 2 1 0 ABC transporter TPR_12 PF13424.6 EGB05243.1 - 5e-15 55.5 32.0 1.9e-05 24.8 7.5 6.1 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05243.1 - 1.1e-12 47.0 27.3 0.0013 18.7 0.2 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05243.1 - 3.3e-10 40.4 43.1 0.0001 22.9 9.0 5.6 6 1 0 6 6 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05243.1 - 9.6e-09 34.8 1.9 0.17 12.2 0.3 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05243.1 - 1.6e-08 34.1 7.8 7.1e-06 25.6 0.1 5.0 5 0 0 5 5 5 1 TPR repeat TPR_1 PF00515.28 EGB05243.1 - 2.6e-08 33.4 22.0 0.00016 21.3 0.2 5.9 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05243.1 - 2.1e-05 24.2 13.7 2.5 8.3 0.5 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB05243.1 - 5.2e-05 23.0 28.1 0.00034 20.4 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_21 PF09976.9 EGB05243.1 - 0.00014 21.7 17.0 0.8 9.4 3.4 4.4 1 1 0 3 3 3 3 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 EGB05243.1 - 0.00025 21.6 49.1 0.093 13.6 2.8 9.3 8 3 3 11 11 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGB05243.1 - 0.0011 19.1 22.7 0.0085 16.2 3.2 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGB05243.1 - 0.0042 17.0 0.6 18 5.5 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB05243.1 - 0.025 14.8 8.1 0.45 10.8 0.1 4.0 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGB05243.1 - 0.027 15.0 31.2 0.062 13.8 5.1 6.5 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05243.1 - 0.39 11.2 6.3 50 4.6 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF982 PF06169.12 EGB05243.1 - 0.94 9.6 4.6 12 6.0 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF982) SNAP PF14938.6 EGB05243.1 - 4.8 6.5 12.6 1.5 8.2 0.0 3.4 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TFCD_C PF12612.8 EGB05244.1 - 1.8e-10 41.0 0.0 1.5e-09 38.0 0.0 2.6 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal NACHT PF05729.12 EGB05245.1 - 7.1e-07 29.3 0.0 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGB05245.1 - 1.4e-06 28.8 2.1 3.3e-06 27.6 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGB05245.1 - 1.8e-05 25.1 0.3 0.00014 22.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 EGB05245.1 - 2.9e-05 24.1 0.0 9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EGB05245.1 - 0.0012 18.1 0.0 0.0046 16.2 0.0 1.8 1 1 0 1 1 1 1 KAP family P-loop domain TRAPPC-Trs85 PF12739.7 EGB05246.1 - 2.1e-24 86.3 0.0 6.2e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF1126 PF06565.12 EGB05247.1 - 9.8e-30 102.5 0.0 2.8e-12 46.4 0.0 3.7 3 1 1 4 4 4 3 DUF1126 PH-like domain TPT PF03151.16 EGB05248.1 - 5.7e-12 45.6 15.9 8e-12 45.1 15.9 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family BUD22 PF09073.10 EGB05249.1 - 0.25 10.6 12.7 0.46 9.8 12.7 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGB05249.1 - 1.7 6.8 12.0 2.3 6.3 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGB05249.1 - 2.5 6.3 15.6 4.6 5.4 15.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 EGB05249.1 - 2.8 7.6 6.2 4.8 6.8 6.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CLP_protease PF00574.23 EGB05250.1 - 2.8e-24 86.0 0.0 3e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Clp protease Kinesin PF00225.23 EGB05251.1 - 2.7e-119 398.0 2.6 6.8e-119 396.7 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGB05251.1 - 1.1e-27 96.8 0.0 5.7e-27 94.5 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 EGB05251.1 - 0.0016 18.6 11.5 0.0063 16.7 11.4 2.2 1 1 0 1 1 1 1 Kinesin-associated DUF812 PF05667.11 EGB05251.1 - 0.083 11.8 31.3 0.13 11.1 31.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NRN1 PF15056.6 EGB05251.1 - 0.096 12.8 0.9 0.33 11.1 0.9 1.9 1 0 0 1 1 1 0 Neuritin protein family DUF1805 PF08827.11 EGB05253.1 - 3.1e-18 65.9 1.1 3.6e-18 65.7 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1805) MFS_1 PF07690.16 EGB05254.1 - 8.9e-24 84.1 29.3 1.5e-23 83.3 29.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB05254.1 - 2.6e-08 33.2 6.9 2.6e-08 33.2 6.9 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGB05254.1 - 0.46 9.3 6.5 9 5.0 6.5 2.6 1 1 0 1 1 1 0 MFS_1 like family Metallophos PF00149.28 EGB05255.1 - 6.2e-18 66.0 0.0 9.5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.6 EGB05255.1 - 3.7e-09 35.8 0.2 0.0018 18.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB05255.1 - 5.5e-09 34.9 0.2 0.00055 19.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB05255.1 - 7.4e-08 31.5 1.2 0.0075 15.7 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB05255.1 - 1.4e-06 28.6 0.0 0.017 15.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB05255.1 - 5.4e-05 22.9 0.0 0.0084 15.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Metallophos_2 PF12850.7 EGB05255.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MbeB_N PF04837.12 EGB05255.1 - 0.025 14.9 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Chloroa_b-bind PF00504.21 EGB05256.1 - 6.5e-38 130.8 0.1 8e-38 130.5 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Guanylate_cyc PF00211.20 EGB05257.1 - 2.2e-08 33.9 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 EGB05257.1 - 0.016 15.6 0.0 0.053 13.9 0.0 1.9 1 0 0 1 1 1 0 HAMP domain BLOC1S3 PF15753.5 EGB05257.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Lig_chan PF00060.26 EGB05258.1 - 5e-11 42.6 0.0 1.3e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel LapA_dom PF06305.11 EGB05258.1 - 0.031 14.1 2.2 0.13 12.1 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SET PF00856.28 EGB05259.1 - 2.2e-09 37.9 0.0 4.1e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EGB05259.1 - 0.13 13.0 0.0 0.33 11.6 0.0 1.6 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding Sulfotransfer_2 PF03567.14 EGB05260.1 - 2.4e-05 24.4 0.0 7.3e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family C2 PF00168.30 EGB05261.1 - 2.1e-20 72.9 0.0 1e-14 54.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 EGB05261.1 - 1.6e-10 39.8 1.2 0.0015 18.0 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB05261.1 - 9.6e-10 38.8 0.0 2.6e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB05261.1 - 7.9e-08 31.6 1.5 0.0038 17.1 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EGB05261.1 - 3.7e-07 29.3 5.9 0.00041 19.7 0.0 3.4 3 0 0 3 3 3 2 EF hand Hydrolase_4 PF12146.8 EGB05261.1 - 1.6e-06 27.6 0.2 3.5e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EF-hand_8 PF13833.6 EGB05261.1 - 4.5e-05 23.2 2.0 0.1 12.5 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair Abhydrolase_1 PF00561.20 EGB05261.1 - 8.1e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Patatin PF01734.22 EGB05261.1 - 0.0056 16.9 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase EF-hand_10 PF14788.6 EGB05261.1 - 0.2 11.6 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 EF hand GMP_PDE_delta PF05351.11 EGB05262.1 - 8.6e-26 90.9 1.5 2.6e-21 76.3 0.0 2.3 1 1 1 2 2 2 2 GMP-PDE, delta subunit Methyltransf_32 PF13679.6 EGB05262.1 - 1.4e-24 86.9 0.8 1.2e-23 83.8 0.8 2.5 1 1 0 1 1 1 1 Methyltransferase domain LysM PF01476.20 EGB05262.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 LysM domain Methyltransf_25 PF13649.6 EGB05262.1 - 0.001 19.7 0.4 0.013 16.2 0.1 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05262.1 - 0.0025 17.6 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB05262.1 - 0.079 12.7 0.1 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4537 PF15057.6 EGB05262.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) CLP_protease PF00574.23 EGB05263.1 - 1.7e-79 266.0 0.0 2e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease Clr5 PF14420.6 EGB05263.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Clr5 domain THP2 PF09432.10 EGB05264.1 - 0.25 11.4 0.0 0.43 10.6 0.0 1.3 1 0 0 1 1 1 0 Tho complex subunit THP2 RrnaAD PF00398.20 EGB05265.1 - 1.2e-62 211.4 0.0 1.4e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGB05265.1 - 4e-09 37.1 0.0 1.2e-08 35.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB05265.1 - 2.6e-06 28.0 0.0 5.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB05265.1 - 2.3e-05 24.3 0.0 3.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGB05265.1 - 9.7e-05 23.0 0.0 0.00024 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGB05265.1 - 0.00014 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EGB05265.1 - 0.00029 20.7 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB05265.1 - 0.00037 20.1 0.0 0.001 18.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.11 EGB05265.1 - 0.0021 17.7 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_31 PF13847.6 EGB05265.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EGB05265.1 - 0.0039 16.9 0.0 0.011 15.4 0.0 1.7 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 EGB05265.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family BLUF PF04940.12 EGB05265.1 - 0.0069 16.5 0.1 0.78 9.9 0.0 2.4 2 0 0 2 2 2 1 Sensors of blue-light using FAD Methyltransf_4 PF02390.17 EGB05265.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 EGB05265.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGB05265.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2358 PF10184.9 EGB05266.1 - 1.7e-12 47.6 0.0 2.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EGB05266.1 - 0.00083 20.0 1.2 0.012 16.3 0.4 2.2 2 0 0 2 2 2 1 SnoaL-like domain ABC_tran PF00005.27 EGB05267.1 - 2.4e-40 138.2 0.0 1.3e-22 80.8 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB05267.1 - 1.8e-14 54.3 1.9 0.00033 20.5 0.0 4.1 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB05267.1 - 1.3e-09 37.9 0.5 0.06 12.8 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGB05267.1 - 5.8e-06 26.6 0.1 0.2 11.9 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EGB05267.1 - 2.1e-05 25.1 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGB05267.1 - 2.2e-05 24.1 0.3 0.046 13.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EGB05267.1 - 2.7e-05 24.0 0.0 0.2 11.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 EGB05267.1 - 3.5e-05 23.8 0.0 0.29 11.0 0.0 2.6 3 0 0 3 3 2 2 NACHT domain RsgA_GTPase PF03193.16 EGB05267.1 - 6.5e-05 22.9 0.2 0.045 13.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 EGB05267.1 - 0.00012 22.2 0.1 0.18 12.1 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 EGB05267.1 - 0.00014 21.9 0.4 0.065 13.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EGB05267.1 - 0.00017 22.1 4.5 0.25 11.8 0.1 2.5 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EGB05267.1 - 0.00074 19.7 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 EGB05267.1 - 0.0011 19.2 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 EGB05267.1 - 0.0017 17.3 0.0 0.028 13.3 0.0 2.0 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 EGB05267.1 - 0.0018 18.7 0.0 0.34 11.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 EGB05267.1 - 0.0021 17.8 0.2 0.66 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 EGB05267.1 - 0.0028 17.3 0.0 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EGB05267.1 - 0.004 17.3 0.9 0.29 11.2 0.1 2.6 3 0 0 3 3 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 EGB05267.1 - 0.0052 17.1 0.1 4.6 7.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 EGB05267.1 - 0.0063 16.3 0.0 17 5.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_7 PF12775.7 EGB05267.1 - 0.0079 15.7 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF3584 PF12128.8 EGB05267.1 - 0.009 13.6 2.8 0.066 10.7 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) AAA PF00004.29 EGB05267.1 - 0.012 16.1 0.0 12 6.4 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 EGB05267.1 - 0.016 14.8 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EGB05267.1 - 0.017 14.3 0.3 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EGB05267.1 - 0.017 15.0 0.5 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 EGB05267.1 - 0.022 13.7 0.3 12 4.7 0.1 3.3 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EGB05267.1 - 0.027 14.5 0.2 4 7.5 0.0 2.8 2 1 1 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGB05267.1 - 0.035 14.4 0.0 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EGB05267.1 - 0.039 13.9 0.0 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 EGB05267.1 - 0.048 13.4 0.0 6.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EGB05267.1 - 0.082 12.2 0.2 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_13 PF13166.6 EGB05267.1 - 0.099 11.3 0.0 8.6 4.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGB05267.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Dynamin family cobW PF02492.19 EGB05267.1 - 0.13 11.9 0.2 14 5.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EGB05267.1 - 0.3 11.1 0.7 19 5.3 0.1 3.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) MoaE PF02391.17 EGB05268.1 - 1.8e-39 134.5 0.9 2e-39 134.3 0.9 1.0 1 0 0 1 1 1 1 MoaE protein Semialdhyde_dh PF01118.24 EGB05269.1 - 1.2e-08 35.4 0.6 3e-06 27.7 0.6 2.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGB05269.1 - 0.053 13.4 1.0 0.11 12.4 1.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding GATase_2 PF00310.21 EGB05270.1 - 4.6e-159 529.6 0.0 6e-159 529.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EGB05270.1 - 3.5e-150 500.2 3.9 1.6e-146 488.2 0.2 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EGB05270.1 - 1e-103 346.7 0.0 3.6e-103 344.9 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EGB05270.1 - 5.1e-75 251.2 1.1 9.7e-75 250.3 1.1 1.5 1 0 0 1 1 1 1 GXGXG motif Ribosomal_L28e PF01778.17 EGB05271.1 - 4.7e-29 101.5 1.0 6.8e-29 100.9 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family PK PF00224.21 EGB05272.1 - 2e-117 392.0 0.0 2.7e-117 391.5 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGB05272.1 - 6.5e-21 74.7 0.1 2e-20 73.2 0.1 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGB05272.1 - 0.00032 19.9 0.1 0.00032 19.9 0.1 2.4 2 1 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family RCC1 PF00415.18 EGB05274.1 - 3.4e-24 85.2 8.7 4.6e-12 46.4 0.8 3.6 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB05274.1 - 6.6e-15 54.5 14.5 1e-11 44.3 0.9 3.2 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat FMN_dh PF01070.18 EGB05275.1 - 1.5e-98 330.0 0.3 1.7e-98 329.8 0.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGB05275.1 - 1.3e-05 24.4 0.1 2.1e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EGB05275.1 - 0.00011 21.7 0.5 0.00027 20.4 0.2 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.17 EGB05275.1 - 0.0003 20.1 0.0 0.00055 19.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EGB05275.1 - 0.036 13.3 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EGB05275.1 - 0.046 13.2 0.1 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Histidine biosynthesis protein Xlink PF00193.17 EGB05275.1 - 0.17 12.3 0.0 2 8.8 0.0 2.3 2 0 0 2 2 2 0 Extracellular link domain Cofac_haem_bdg PF04187.13 EGB05276.1 - 4.7e-51 173.8 0.2 4.7e-51 173.8 0.2 1.8 2 0 0 2 2 2 1 Haem-binding uptake, Tiki superfamily, ChaN Mito_carr PF00153.27 EGB05276.1 - 2.4e-44 149.2 4.4 3.6e-18 65.3 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein RCC1 PF00415.18 EGB05276.1 - 4.1e-21 75.4 9.2 1.6e-06 28.6 0.0 6.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB05276.1 - 6e-12 45.0 34.6 2.9e-05 23.7 1.4 6.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Synaptobrevin PF00957.21 EGB05277.1 - 1.2e-29 101.9 0.7 1.8e-29 101.4 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGB05277.1 - 1.1e-23 83.1 0.0 1.7e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain LOH1CR12 PF10158.9 EGB05277.1 - 0.11 12.5 0.2 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Tumour suppressor protein CRM1_C PF08767.11 EGB05278.1 - 5.3e-117 390.5 0.1 2.1e-115 385.3 0.0 2.2 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 EGB05278.1 - 5.7e-35 120.6 0.2 1.8e-34 119.0 0.2 1.9 1 0 0 1 1 1 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGB05278.1 - 2.2e-30 104.1 0.2 7.1e-30 102.5 0.2 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGB05278.1 - 1.7e-29 101.6 0.7 1.7e-29 101.6 0.7 2.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGB05278.1 - 1.1e-17 63.2 0.1 2.4e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGB05278.1 - 4.6e-10 39.3 0.0 1.5e-09 37.6 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Glyco_hydro_67M PF07488.12 EGB05279.1 - 4.4e-84 282.3 0.0 6.5e-76 255.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 EGB05279.1 - 2.5e-43 148.2 0.0 4.3e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 67 C-terminus UPF0029 PF01205.19 EGB05279.1 - 3.2e-15 56.3 0.0 8.4e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RGS PF00615.19 EGB05279.1 - 2.4e-10 40.7 0.0 4.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain EF-hand_1 PF00036.32 EGB05279.1 - 3.5e-10 38.7 3.1 0.00043 19.6 0.0 3.4 3 0 0 3 3 3 2 EF hand Methyltransf_16 PF10294.9 EGB05279.1 - 9.2e-10 38.5 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase EF-hand_6 PF13405.6 EGB05279.1 - 1.6e-07 30.7 1.2 0.015 15.2 0.3 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGB05279.1 - 1.4e-06 28.6 1.9 0.025 15.0 0.4 3.0 3 0 0 3 3 3 2 EF-hand domain pair Ricin_B_lectin PF00652.22 EGB05279.1 - 3.9e-06 27.1 0.0 0.0042 17.3 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain EF-hand_5 PF13202.6 EGB05279.1 - 6.1e-06 25.5 5.2 0.003 17.0 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGB05279.1 - 0.00013 21.7 0.3 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Methyltransf_23 PF13489.6 EGB05279.1 - 0.0003 20.7 0.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Glyco_hydro_20b PF02838.15 EGB05279.1 - 0.00035 21.3 0.0 0.00091 20.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Methyltransf_25 PF13649.6 EGB05279.1 - 0.042 14.6 0.1 0.12 13.0 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGB05279.1 - 0.085 13.5 0.1 0.24 12.1 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 EGB05280.1 - 7.4e-42 143.1 0.0 1.9e-41 141.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB05280.1 - 9.8e-24 83.8 0.0 1.8e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 EGB05280.1 - 7e-20 71.3 0.1 1.7e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 SPRY domain AAA_22 PF13401.6 EGB05280.1 - 0.034 14.4 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EGB05280.1 - 0.084 12.9 0.0 3.4 7.6 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EGB05280.1 - 0.24 10.9 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Mito_carr PF00153.27 EGB05281.1 - 2.5e-20 72.2 2.0 2.7e-11 43.2 0.1 2.3 1 1 1 2 2 2 2 Mitochondrial carrier protein L_biotic_typeA PF04604.13 EGB05281.1 - 0.031 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Type-A lantibiotic PseudoU_synth_1 PF01416.20 EGB05282.1 - 3e-06 27.7 0.0 0.0003 21.2 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF4054 PF13262.6 EGB05282.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) DUF2344 PF10105.9 EGB05282.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF615 PF04751.14 EGB05282.1 - 0.038 14.0 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) PSK_trans_fac PF07704.11 EGB05282.1 - 0.05 14.4 2.5 10 6.9 0.0 2.5 2 1 0 2 2 2 0 Rv0623-like transcription factor zf-RING_2 PF13639.6 EGB05284.1 - 3e-10 40.3 7.3 3e-10 40.3 7.3 1.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 EGB05284.1 - 5.9e-08 32.3 2.5 1.1e-07 31.5 2.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGB05284.1 - 1e-06 28.4 7.9 2.2e-06 27.4 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB05284.1 - 5.5e-06 26.6 7.4 2.2e-05 24.6 7.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGB05284.1 - 5.6e-06 26.3 1.0 5.6e-06 26.3 1.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGB05284.1 - 1.2e-05 25.0 4.0 2.2e-05 24.2 4.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EGB05284.1 - 1.5e-05 24.8 7.6 2.9e-05 23.8 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB05284.1 - 0.00013 21.8 7.7 0.00028 20.8 7.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGB05284.1 - 0.0018 18.1 5.5 0.003 17.4 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) T6SS-SciN PF12790.7 EGB05284.1 - 0.02 14.6 0.9 0.029 14.1 0.9 1.2 1 0 0 1 1 1 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 zf-ANAPC11 PF12861.7 EGB05284.1 - 0.047 13.7 3.9 0.13 12.3 3.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGB05284.1 - 0.15 12.0 9.7 0.29 11.0 9.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SPX PF03105.19 EGB05284.1 - 0.4 10.5 1.9 0.41 10.5 1.9 1.2 1 0 0 1 1 1 0 SPX domain PHD PF00628.29 EGB05284.1 - 0.86 9.6 5.8 1.7 8.6 5.8 1.5 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 EGB05284.1 - 1.1 9.5 5.8 4.6 7.5 5.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DER1 PF04511.15 EGB05285.1 - 1.5e-57 194.6 10.0 1.8e-57 194.4 10.0 1.0 1 0 0 1 1 1 1 Der1-like family Na_Ca_ex PF01699.24 EGB05286.1 - 3.9e-34 117.8 19.7 2.2e-18 66.7 2.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_1 PF00036.32 EGB05286.1 - 5.6e-10 38.1 14.5 0.00014 21.2 0.4 4.9 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 EGB05286.1 - 9.5e-10 37.5 12.5 0.0007 19.0 0.2 5.3 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EGB05286.1 - 1.2e-09 38.5 11.1 1.7e-05 25.2 2.1 3.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB05286.1 - 1.9e-08 33.5 10.3 0.00017 21.2 0.3 4.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 EGB05286.1 - 8.8e-05 22.3 9.7 0.043 13.7 0.4 4.3 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB05286.1 - 0.012 15.9 0.1 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Hamartin PF04388.12 EGB05286.1 - 1.3 7.6 26.0 2.3 6.8 26.0 1.3 1 0 0 1 1 1 0 Hamartin protein DUF4281 PF14108.6 EGB05287.1 - 2e-29 102.5 0.6 4.3e-29 101.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) Myb_DNA-binding PF00249.31 EGB05287.1 - 1.3e-18 66.9 2.3 1.5e-07 31.5 0.0 4.4 5 0 0 5 5 4 3 Myb-like DNA-binding domain Glycos_transf_2 PF00535.26 EGB05287.1 - 4.6e-13 49.3 0.1 9.5e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Myb_DNA-bind_6 PF13921.6 EGB05287.1 - 1.5e-12 47.6 0.0 3.9e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain JAB PF01398.21 EGB05287.1 - 1.8e-09 37.6 0.0 3.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGB05287.1 - 6.5e-06 25.9 0.1 3e-05 23.8 0.1 2.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PWWP PF00855.17 EGB05287.1 - 0.00014 22.2 3.8 0.0003 21.1 3.8 1.6 1 0 0 1 1 1 1 PWWP domain Glyco_tranf_2_3 PF13641.6 EGB05287.1 - 0.0039 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Myb_DNA-bind_4 PF13837.6 EGB05287.1 - 0.011 16.1 0.7 0.2 12.1 0.3 3.0 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EGB05287.1 - 0.34 11.0 1.1 4.9 7.3 0.1 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain BUD22 PF09073.10 EGB05287.1 - 9.9 5.4 11.9 19 4.4 11.9 1.4 1 0 0 1 1 1 0 BUD22 Pyr_redox_2 PF07992.14 EGB05288.1 - 2.1e-07 30.5 5.4 3.5e-06 26.5 5.4 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Exostosin PF03016.15 EGB05288.1 - 0.00031 20.1 0.0 0.00056 19.2 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Pyr_redox PF00070.27 EGB05288.1 - 0.035 14.7 0.0 0.2 12.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ParA PF10609.9 EGB05289.1 - 3.4e-54 183.9 0.0 3.8e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGB05289.1 - 1.1e-12 48.2 0.0 1.5e-12 47.7 0.0 1.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGB05289.1 - 2.1e-09 37.6 0.0 4.5e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EGB05289.1 - 2.9e-06 26.8 0.0 4.8e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ VirC1 PF07015.11 EGB05289.1 - 4e-05 23.0 0.1 0.00011 21.6 0.0 1.6 2 0 0 2 2 2 1 VirC1 protein ArsA_ATPase PF02374.15 EGB05289.1 - 9.9e-05 21.7 2.0 0.0059 15.8 0.3 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 EGB05289.1 - 0.0014 18.5 0.1 0.07 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 EGB05289.1 - 0.0091 15.5 0.0 0.016 14.7 0.0 1.3 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Glyco_trans_4_4 PF13579.6 EGB05289.1 - 0.021 15.3 2.8 0.036 14.5 2.8 1.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain MeaB PF03308.16 EGB05289.1 - 0.023 13.7 0.2 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGB05289.1 - 0.058 13.9 0.0 0.065 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EGB05289.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 EGB05289.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_NifH PF00142.18 EGB05289.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1611 PF07755.11 EGB05289.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Syntaxin PF00804.25 EGB05290.1 - 6.3e-33 114.1 4.4 8e-33 113.8 4.4 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EGB05290.1 - 1.2e-08 34.8 2.6 5.2e-08 32.8 0.2 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 EGB05290.1 - 1.9e-06 28.2 3.0 1.9e-06 28.2 3.0 2.2 2 0 0 2 2 2 1 Syntaxin-like protein MIS13 PF08202.11 EGB05290.1 - 0.00097 18.5 1.3 0.41 9.9 0.1 2.1 2 0 0 2 2 2 2 Mis12-Mtw1 protein family SseC PF04888.12 EGB05290.1 - 0.017 14.8 0.1 0.036 13.7 0.1 1.6 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family FadA PF09403.10 EGB05290.1 - 0.033 14.7 8.3 0.31 11.5 3.6 2.5 2 1 0 2 2 2 0 Adhesion protein FadA DUF948 PF06103.11 EGB05290.1 - 0.49 10.7 6.9 0.68 10.2 1.3 3.4 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HisKA PF00512.25 EGB05290.1 - 1.4 9.0 4.0 41 4.3 0.0 3.2 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Fib_alpha PF08702.10 EGB05290.1 - 1.5 9.0 8.2 3.6 7.7 3.1 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EGB05290.1 - 8.9 6.9 9.1 2.6 8.6 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 Methyltransf_25 PF13649.6 EGB05291.1 - 3.5e-05 24.4 0.1 0.00012 22.7 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB05291.1 - 3.7e-05 24.3 0.0 0.00011 22.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB05291.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pirin PF02678.16 EGB05291.1 - 0.00067 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGB05291.1 - 0.0017 18.6 0.0 0.0048 17.2 0.0 1.7 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Methyltransf_12 PF08242.12 EGB05291.1 - 0.0045 17.7 0.0 0.017 15.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05291.1 - 0.014 15.2 0.0 6.7 6.5 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EGB05291.1 - 0.042 13.4 0.1 0.097 12.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PilJ PF13675.6 EGB05291.1 - 0.11 12.5 0.2 3.8 7.6 0.1 2.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term PrmA PF06325.13 EGB05291.1 - 0.21 10.9 0.7 0.35 10.2 0.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Trypan_PARP PF05887.11 EGB05291.1 - 0.23 11.4 13.8 0.099 12.6 9.9 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3098 PF11297.8 EGB05292.1 - 0.062 12.9 0.2 30 4.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) ABC_membrane PF00664.23 EGB05293.1 - 2.3e-51 175.1 0.7 2.8e-51 174.8 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB05293.1 - 8.3e-31 107.3 0.0 1.3e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGB05293.1 - 1.6e-07 31.0 0.5 0.00011 21.7 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB05293.1 - 2.4e-06 28.0 0.5 1.1e-05 25.9 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EGB05293.1 - 0.00011 21.8 2.2 0.00098 18.8 2.2 2.2 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EGB05293.1 - 0.00056 18.8 0.1 0.00098 18.0 0.1 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class ABC_membrane_2 PF06472.15 EGB05293.1 - 0.00056 19.4 0.1 0.00088 18.8 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_22 PF13401.6 EGB05293.1 - 0.00095 19.4 0.8 0.025 14.9 0.4 2.7 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGB05293.1 - 0.014 15.6 2.3 0.23 11.7 2.3 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGB05293.1 - 0.016 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGB05293.1 - 0.035 13.8 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGB05293.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGB05293.1 - 0.047 13.5 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGB05293.1 - 0.076 13.4 0.1 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGB05293.1 - 0.14 11.4 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Helicase_C PF00271.31 EGB05294.1 - 1.9e-09 37.8 0.0 4.8e-08 33.3 0.0 2.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Ank_2 PF12796.7 EGB05295.1 - 3.2e-16 59.7 6.3 2.3e-07 31.3 0.1 5.0 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB05295.1 - 5.4e-15 55.5 4.2 7.8e-07 29.5 0.0 6.1 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB05295.1 - 5.3e-10 39.3 12.2 0.008 16.5 0.0 6.2 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB05295.1 - 5e-09 35.7 2.9 0.3 11.8 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 EGB05295.1 - 0.00066 20.0 10.7 0.037 14.5 0.1 5.5 4 1 0 4 4 4 1 Ankyrin repeat Phostensin_N PF13916.6 EGB05295.1 - 0.0055 17.0 0.0 6.9 7.1 0.0 2.8 2 0 0 2 2 2 2 PP1-regulatory protein, Phostensin N-terminal UBA PF00627.31 EGB05295.1 - 0.096 12.6 0.4 13 5.8 0.1 3.7 3 0 0 3 3 3 0 UBA/TS-N domain UTP15_C PF09384.10 EGB05295.1 - 0.24 11.1 2.2 11 5.7 0.1 2.4 2 0 0 2 2 2 0 UTP15 C terminal PP2C PF00481.21 EGB05296.1 - 3.5e-35 121.9 0.0 4.7e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB05296.1 - 3.4e-05 23.6 0.3 0.00018 21.2 0.3 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L18 PF17135.4 EGB05296.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Pkinase PF00069.25 EGB05297.1 - 7.7e-53 179.5 0.0 8.7e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05297.1 - 1.5e-35 122.7 0.0 1.8e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05297.1 - 1.1e-07 31.5 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB05297.1 - 0.0006 19.2 0.9 0.00083 18.8 0.9 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB05297.1 - 0.011 15.6 1.4 0.028 14.3 1.4 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB05297.1 - 0.049 12.4 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGB05297.1 - 0.05 12.6 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Aldo_ket_red PF00248.21 EGB05298.1 - 8.5e-63 212.3 0.0 9.6e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RCC1_2 PF13540.6 EGB05298.1 - 0.068 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat DUF1864 PF08933.11 EGB05298.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) DUF4536 PF15055.6 EGB05298.1 - 8.4 6.7 5.7 3.3 8.0 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4536) FBPase PF00316.20 EGB05300.1 - 8e-68 227.6 0.2 1.2e-67 227.0 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EGB05300.1 - 0.086 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Inositol monophosphatase family TDA11 PF17084.5 EGB05300.1 - 0.11 11.4 0.0 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 Topoisomerase I damage affected protein 11 AAA_6 PF12774.7 EGB05302.1 - 2e-152 506.9 0.0 5.2e-151 502.2 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB05302.1 - 4.1e-124 414.7 4.5 4.1e-124 414.7 4.5 3.1 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGB05302.1 - 2.4e-102 341.7 0.6 6.4e-102 340.3 0.6 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGB05302.1 - 3.2e-98 328.7 0.0 9.6e-98 327.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGB05302.1 - 8.5e-88 293.2 0.5 2.9e-86 288.1 0.1 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGB05302.1 - 6.6e-80 266.9 0.0 1.4e-74 249.6 0.0 4.0 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB05302.1 - 3.3e-50 170.1 0.1 1.3e-49 168.2 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB05302.1 - 9.2e-46 154.8 0.0 2.2e-41 140.7 0.0 3.6 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGB05302.1 - 1e-45 156.3 10.4 1e-45 156.3 10.4 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EGB05302.1 - 1.4e-28 99.6 0.0 3.9e-28 98.1 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGB05302.1 - 1.4e-22 80.1 0.4 1.8e-07 31.2 0.0 6.1 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGB05302.1 - 3.8e-20 71.9 0.1 1.3e-19 70.3 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGB05302.1 - 3.4e-05 24.1 2.7 0.91 9.8 0.0 5.2 5 0 0 5 5 4 1 AAA domain AAA PF00004.29 EGB05302.1 - 4e-05 24.1 0.0 0.44 11.0 0.0 4.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGB05302.1 - 0.00014 22.4 0.2 0.16 12.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 EGB05302.1 - 0.0002 20.5 1.9 0.035 13.2 0.0 3.9 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_16 PF13191.6 EGB05302.1 - 0.00031 21.2 1.5 8.5 6.7 0.0 4.9 4 1 0 4 4 4 0 AAA ATPase domain RNA_helicase PF00910.22 EGB05302.1 - 0.00045 20.6 0.1 1.4 9.3 0.0 4.0 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 EGB05302.1 - 0.0027 17.5 0.8 6.1 6.5 0.6 3.5 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EGB05302.1 - 0.0028 17.1 3.3 3.9 6.8 0.0 4.4 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGB05302.1 - 0.0047 17.1 0.1 18 5.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain DUF853 PF05872.12 EGB05302.1 - 0.0058 15.3 1.4 4.9 5.6 0.0 3.3 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) Rad17 PF03215.15 EGB05302.1 - 0.067 13.1 0.1 7.9 6.4 0.0 3.3 3 0 0 3 3 3 0 Rad17 P-loop domain ABC_tran PF00005.27 EGB05302.1 - 0.17 12.4 0.2 14 6.2 0.0 3.4 2 0 0 2 2 2 0 ABC transporter SCAB_CC PF16712.5 EGB05302.1 - 2.3 8.0 12.9 0.012 15.4 3.4 2.1 2 0 0 2 2 1 0 Coiled-coil regions of plant-specific actin-binding protein FUSC PF04632.12 EGB05302.1 - 2.6 6.5 4.3 2.7 6.4 0.6 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF4363 PF14276.6 EGB05302.1 - 7 6.8 10.8 1.7 8.8 0.7 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) Abhydrolase_1 PF00561.20 EGB05303.1 - 1.6e-15 57.5 0.1 1.2e-12 48.1 0.2 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB05303.1 - 6.2e-15 56.4 17.4 2.8e-14 54.2 17.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB05303.1 - 6.5e-10 38.7 3.8 1.8e-09 37.2 2.5 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EGB05303.1 - 0.059 13.5 0.2 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein DUF676 PF05057.14 EGB05303.1 - 0.086 12.3 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Sugar_tr PF00083.24 EGB05304.1 - 3.1e-87 293.3 19.6 3.6e-87 293.1 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB05304.1 - 1.8e-21 76.4 66.4 1.2e-20 73.8 38.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HlyIII PF03006.20 EGB05305.1 - 3.8e-34 118.4 15.8 4.4e-34 118.2 15.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF373 PF04123.13 EGB05305.1 - 4 6.8 7.4 5 6.5 7.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) AtuA PF07287.11 EGB05306.1 - 5.1e-67 226.1 0.1 9.3e-67 225.2 0.1 1.4 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA 2OG-FeII_Oxy_3 PF13640.6 EGB05307.1 - 4.6e-07 30.6 0.1 8.6e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p25-alpha PF05517.12 EGB05309.1 - 3.5e-13 50.0 0.7 5.8e-13 49.3 0.7 1.3 1 0 0 1 1 1 1 p25-alpha DUF416 PF04222.12 EGB05309.1 - 0.008 15.6 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF416) Peptidase_S55 PF05580.12 EGB05309.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 SpoIVB peptidase S55 FG-GAP_2 PF14312.6 EGB05310.1 - 3.2e-24 84.9 62.8 1.8e-05 24.9 4.6 6.7 6 0 0 6 6 6 6 FG-GAP repeat CE2_N PF17996.1 EGB05310.1 - 0.0068 16.4 4.6 6 6.9 0.0 4.6 3 1 1 4 4 4 2 Carbohydrate esterase 2 N-terminal HTH_43 PF09904.9 EGB05310.1 - 0.012 15.5 16.1 17 5.4 0.1 6.2 6 0 0 6 6 6 0 Winged helix-turn helix DUF4778 PF16008.5 EGB05310.1 - 0.72 9.9 7.3 1 9.4 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) UCH PF00443.29 EGB05311.1 - 2.6e-29 102.5 0.0 3.5e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB05311.1 - 1e-19 71.3 0.0 4.1e-14 52.9 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Cys_rich_CPXG PF14255.6 EGB05311.1 - 0.066 13.1 2.4 0.12 12.3 0.2 2.5 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-dskA_traR PF01258.17 EGB05311.1 - 0.25 11.3 2.6 0.49 10.4 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-RanBP PF00641.18 EGB05312.1 - 0.073 12.4 9.4 0.12 11.7 9.4 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others RecR PF02132.15 EGB05312.1 - 6.5 6.4 13.6 1.7 8.3 3.2 3.2 3 0 0 3 3 3 0 RecR protein EF-hand_7 PF13499.6 EGB05313.1 - 0.00029 21.2 0.0 0.00063 20.1 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB05313.1 - 0.0055 16.5 0.1 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGB05313.1 - 0.033 13.7 0.2 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 EGB05313.1 - 0.17 11.8 0.3 0.42 10.5 0.1 1.7 2 0 0 2 2 2 0 EF-hand domain pair DnaJ PF00226.31 EGB05314.1 - 2.2e-26 91.8 1.9 2.4e-26 91.6 1.9 1.0 1 0 0 1 1 1 1 DnaJ domain DUF1366 PF07104.11 EGB05314.1 - 0.017 14.8 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) RPT PF13446.6 EGB05314.1 - 0.066 13.2 0.1 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 A repeated domain in UCH-protein Mem_trans PF03547.18 EGB05315.1 - 0.86 7.9 14.0 1.4 7.3 0.3 2.1 2 0 0 2 2 2 0 Membrane transport protein SnoaL PF07366.12 EGB05316.1 - 0.00017 21.3 0.1 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase WD40 PF00400.32 EGB05316.1 - 0.0025 18.6 1.2 1.7 9.7 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat GSK-3_bind PF05350.12 EGB05316.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.5 3 0 0 3 3 3 0 Glycogen synthase kinase-3 binding adh_short_C2 PF13561.6 EGB05318.1 - 6.1e-52 176.5 0.4 8.1e-52 176.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB05318.1 - 2.7e-39 134.6 0.2 3.3e-39 134.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB05318.1 - 1.8e-12 47.5 0.0 4.1e-10 39.8 0.1 2.0 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 EGB05318.1 - 0.00062 19.3 0.1 0.0019 17.7 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family SBP_bac_1 PF01547.25 EGB05318.1 - 0.011 15.7 0.2 0.022 14.7 0.1 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein LDcluster4 PF18306.1 EGB05318.1 - 0.033 13.8 0.8 0.058 13.0 0.8 1.4 1 0 0 1 1 1 0 SLOG cluster4 family EF-hand_1 PF00036.32 EGB05319.1 - 3.6e-13 48.0 0.3 1.9e-05 23.8 0.0 2.2 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB05319.1 - 9.5e-13 47.0 0.3 4.8e-05 23.0 0.2 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB05319.1 - 6.6e-12 44.4 1.5 1.4e-05 24.4 0.0 2.6 2 1 1 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB05319.1 - 6.5e-09 36.1 0.1 5.9e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB05319.1 - 2.2e-05 24.2 0.8 0.045 13.6 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB05319.1 - 0.0046 17.3 0.0 0.0054 17.0 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain IFT46_B_C PF12317.8 EGB05321.1 - 4.9e-91 304.2 0.1 5.6e-91 304.0 0.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Hfx_Cass5 PF18287.1 EGB05321.1 - 0.087 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 Cupin_8 PF13621.6 EGB05322.1 - 1.8e-37 129.5 0.0 2.6e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Acyltransferase PF01553.21 EGB05322.1 - 8.2e-18 64.3 0.0 1.5e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EamA PF00892.20 EGB05322.1 - 3.2e-05 24.1 10.7 3.2e-05 24.1 10.7 2.9 3 0 0 3 3 3 2 EamA-like transporter family Cupin_4 PF08007.12 EGB05322.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein SH3_3 PF08239.11 EGB05322.1 - 0.13 12.5 1.1 0.43 10.9 1.1 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain Rhomboid PF01694.22 EGB05323.1 - 1.8e-17 63.7 18.2 3e-17 63.0 18.2 1.3 1 0 0 1 1 1 1 Rhomboid family NOA36 PF06524.12 EGB05323.1 - 0.0011 18.4 8.2 0.0011 18.4 8.2 2.3 2 0 0 2 2 2 1 NOA36 protein RXT2_N PF08595.11 EGB05323.1 - 0.029 14.4 5.0 0.096 12.7 2.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 EGB05323.1 - 1.5 8.4 6.6 2.3 7.9 2.8 2.8 3 0 0 3 3 3 0 FAM176 family Cwf_Cwc_15 PF04889.12 EGB05323.1 - 3.5 7.3 24.4 0.14 11.9 12.5 2.5 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EGB05323.1 - 4.2 5.5 4.8 8 4.5 4.8 1.3 1 0 0 1 1 1 0 Nop14-like family 2OG-FeII_Oxy_3 PF13640.6 EGB05324.1 - 1.1e-10 42.2 0.0 3.4e-09 37.5 0.0 2.7 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Baculo_PEP_C PF04513.12 EGB05324.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_1 PF00036.32 EGB05325.1 - 0.0034 16.8 0.1 0.0034 16.8 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGB05325.1 - 0.04 14.4 1.7 0.09 13.2 0.0 2.1 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 EGB05325.1 - 0.05 13.5 0.2 0.05 13.5 0.2 1.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EGB05325.1 - 0.38 10.8 1.8 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain HCO3_cotransp PF00955.21 EGB05326.1 - 7.7e-98 328.5 3.6 1.1e-51 176.2 1.0 2.0 1 1 1 2 2 2 2 HCO3- transporter family Htr2 PF17909.1 EGB05326.1 - 1 9.7 7.5 0.23 11.8 0.3 3.1 2 1 0 2 2 2 0 Htr2 transmembrane domain DHC_N1 PF08385.12 EGB05327.1 - 2.9e-34 118.7 0.0 3.2e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 RVT_thumb PF06817.14 EGB05327.1 - 0.035 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase thumb domain AAA_6 PF12774.7 EGB05328.1 - 4.1e-82 275.8 0.0 4.6e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 EGB05328.1 - 4.7e-05 23.4 0.0 0.17 11.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EGB05328.1 - 0.00048 20.5 0.0 0.00092 19.6 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB05328.1 - 0.0031 17.9 0.0 0.0046 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGB05328.1 - 0.011 16.3 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGB05328.1 - 0.014 15.6 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB05328.1 - 0.18 11.5 0.5 0.38 10.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGB05328.1 - 0.18 11.3 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EGB05329.1 - 7.6e-08 32.5 0.0 1.5e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 EGB05329.1 - 0.0019 17.3 0.0 0.033 13.2 0.0 2.1 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region RsgA_GTPase PF03193.16 EGB05329.1 - 0.0094 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_19 PF13245.6 EGB05329.1 - 0.011 16.0 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB05329.1 - 0.017 15.5 0.6 0.017 15.5 0.6 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EGB05329.1 - 0.045 13.5 0.8 0.045 13.5 0.8 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EGB05329.1 - 0.07 13.6 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EGB05329.1 - 0.082 12.7 0.5 0.22 11.3 0.5 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB05329.1 - 0.2 11.9 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGB05329.1 - 0.24 11.2 0.1 0.37 10.5 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_8 PF12780.7 EGB05330.1 - 1.5e-40 139.1 0.0 2.6e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 EGB05330.1 - 8.9e-24 84.1 8.1 1.2e-23 83.7 8.1 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA PF00004.29 EGB05330.1 - 2.4e-06 28.0 0.1 9.1e-06 26.1 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB05330.1 - 2.4e-06 27.9 4.4 0.0013 19.0 0.1 3.8 3 2 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EGB05330.1 - 1.8e-05 24.8 0.0 4.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EGB05330.1 - 0.0021 17.3 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TMF_DNA_bd PF12329.8 EGB05330.1 - 0.0073 16.3 2.9 0.0073 16.3 2.9 2.9 2 1 0 2 2 1 1 TATA element modulatory factor 1 DNA binding DUF4795 PF16043.5 EGB05330.1 - 0.009 15.6 1.0 0.009 15.6 1.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) SHE3 PF17078.5 EGB05330.1 - 0.021 14.6 0.5 0.021 14.6 0.5 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 T3SSipB PF16535.5 EGB05330.1 - 0.022 15.2 4.5 0.022 15.2 4.5 2.9 2 1 0 2 2 2 0 Type III cell invasion protein SipB RuvB_N PF05496.12 EGB05330.1 - 0.031 14.0 0.1 0.091 12.5 0.0 1.8 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain DivIC PF04977.15 EGB05330.1 - 0.031 14.0 0.2 0.031 14.0 0.2 3.6 3 1 1 4 4 3 0 Septum formation initiator AAA_16 PF13191.6 EGB05330.1 - 0.043 14.2 0.3 0.043 14.2 0.3 4.3 3 2 1 4 4 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGB05330.1 - 0.048 13.6 1.4 0.12 12.3 0.0 2.3 4 0 0 4 4 2 0 RsgA GTPase Fib_alpha PF08702.10 EGB05330.1 - 0.056 13.6 0.1 0.056 13.6 0.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EGB05330.1 - 0.067 13.7 2.6 0.32 11.5 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.27 EGB05330.1 - 0.072 13.6 1.0 0.79 10.2 0.0 2.7 3 0 0 3 3 2 0 ABC transporter MPS2 PF17060.5 EGB05330.1 - 0.076 12.3 0.2 0.076 12.3 0.2 1.8 2 0 0 2 2 2 0 Monopolar spindle protein 2 Atg14 PF10186.9 EGB05330.1 - 0.12 11.4 12.9 0.38 9.8 0.6 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 EGB05330.1 - 0.16 10.1 9.2 0.028 12.6 0.3 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA IFT57 PF10498.9 EGB05330.1 - 0.18 10.7 13.3 1.3 7.9 0.9 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 AAA_29 PF13555.6 EGB05330.1 - 0.18 11.5 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Laminin_I PF06008.14 EGB05330.1 - 0.23 11.2 18.2 0.68 9.6 0.8 2.3 2 0 0 2 2 2 0 Laminin Domain I Fez1 PF06818.15 EGB05330.1 - 0.55 10.7 21.9 0.031 14.7 2.9 2.3 2 0 0 2 2 2 0 Fez1 AAA_23 PF13476.6 EGB05330.1 - 0.81 10.2 8.6 51 4.3 0.2 3.1 3 0 0 3 3 3 0 AAA domain UPF0242 PF06785.11 EGB05330.1 - 0.91 9.6 18.3 0.82 9.7 1.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin PF00261.20 EGB05330.1 - 1.5 8.1 30.0 0.19 11.1 1.9 2.9 3 0 0 3 3 3 0 Tropomyosin DUF16 PF01519.16 EGB05330.1 - 2.9 8.4 10.5 0.9 10.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA_13 PF13166.6 EGB05330.1 - 3.7 6.1 12.4 0.32 9.6 0.7 2.2 2 0 0 2 2 2 0 AAA domain FlaC_arch PF05377.11 EGB05330.1 - 4.4 7.8 7.6 0.99 9.8 1.0 3.1 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Helicase_C PF00271.31 EGB05332.1 - 2e-12 47.4 0.0 3.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGB05332.1 - 1.6e-11 43.5 0.0 2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Lipocalin_2 PF08212.12 EGB05333.1 - 1.3e-23 83.6 0.0 1.6e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Thioredoxin PF00085.20 EGB05334.1 - 2.9e-45 152.5 0.0 4.1e-23 81.3 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 EGB05334.1 - 1.2e-14 54.2 1.1 5.8e-06 26.4 0.1 2.6 2 2 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EGB05334.1 - 1.8e-11 44.2 0.0 0.00044 20.5 0.0 2.7 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB05334.1 - 1.1e-10 41.9 0.1 0.0013 19.1 0.0 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EGB05334.1 - 4.6e-07 29.7 0.0 0.031 14.0 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 EGB05334.1 - 7.3e-06 26.0 0.0 0.094 12.5 0.0 2.1 2 0 0 2 2 2 2 F plasmid transfer operon protein Glutaredoxin PF00462.24 EGB05334.1 - 1.7e-05 24.9 0.0 0.3 11.3 0.0 2.3 2 0 0 2 2 2 2 Glutaredoxin DSBA PF01323.20 EGB05334.1 - 0.021 14.6 0.0 8.4 6.1 0.0 2.6 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Gp37 PF09646.10 EGB05334.1 - 0.082 12.7 0.0 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Gp37 protein La PF05383.17 EGB05334.1 - 0.091 12.8 0.0 21 5.2 0.0 2.3 2 0 0 2 2 2 0 La domain ABC_tran_Xtn PF12848.7 EGB05334.1 - 0.23 11.5 0.0 31 4.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Mu-like_Com PF10122.9 EGB05334.1 - 0.5 9.9 2.8 22 4.6 0.2 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-MYND PF01753.18 EGB05335.1 - 6.7e-10 38.9 14.1 1.6e-09 37.6 14.1 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGB05335.1 - 0.001 19.3 5.9 0.0025 18.1 5.9 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-B_box PF00643.24 EGB05335.1 - 0.46 10.7 2.8 1 9.5 2.8 1.6 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_3 PF13920.6 EGB05335.1 - 0.65 9.9 6.7 1.4 8.8 6.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.13 EGB05335.1 - 0.75 7.6 3.2 0.99 7.2 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ribosomal_L7Ae PF01248.26 EGB05336.1 - 6.3e-23 80.3 0.0 7.2e-23 80.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 EGB05337.1 - 1.3e-72 244.4 0.0 1.5e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05337.1 - 1.7e-31 109.4 0.0 4.1e-31 108.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05337.1 - 0.0025 17.2 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB05337.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB05337.1 - 0.02 13.9 0.0 0.77 8.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGB05337.1 - 0.093 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGB05337.1 - 0.26 10.6 0.0 0.74 9.1 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 3HCDH_N PF02737.18 EGB05338.1 - 3.3e-53 180.3 0.1 4.4e-53 179.8 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGB05338.1 - 1.9e-30 105.3 0.0 4.7e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGB05338.1 - 0.0012 19.1 3.3 0.0084 16.3 3.3 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EGB05338.1 - 0.011 15.1 1.0 0.022 14.1 0.7 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGB05338.1 - 0.013 15.0 0.4 0.022 14.3 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EGB05338.1 - 0.048 14.3 3.5 0.18 12.4 3.5 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MORN PF02493.20 EGB05338.1 - 0.13 12.2 0.3 0.29 11.1 0.3 1.6 1 0 0 1 1 1 0 MORN repeat Sulfotransfer_2 PF03567.14 EGB05339.1 - 0.00056 19.9 0.0 0.00092 19.2 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Phosphoprotein PF00922.17 EGB05340.1 - 0.056 13.0 0.1 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Glyco_transf_25 PF01755.17 EGB05341.1 - 2e-08 34.3 0.0 1.8e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NAD_binding_9 PF13454.6 EGB05341.1 - 2.3e-08 34.2 0.2 0.41 10.6 0.1 4.8 4 0 0 4 4 4 3 FAD-NAD(P)-binding K_oxygenase PF13434.6 EGB05341.1 - 5.9e-08 32.2 0.0 2.4e-05 23.7 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGB05341.1 - 1.3e-07 31.2 0.0 5.4e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_tranf_2_4 PF13704.6 EGB05341.1 - 0.00016 22.1 0.0 0.00047 20.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF707 PF05212.12 EGB05341.1 - 0.014 14.7 0.1 0.039 13.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF707) Pyr_redox PF00070.27 EGB05341.1 - 0.078 13.5 0.1 0.44 11.1 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 EGB05343.1 - 1.6e-06 28.8 0.0 2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB05343.1 - 0.00013 22.2 0.0 0.00035 20.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Tyr-DNA_phospho PF06087.12 EGB05345.1 - 2.8e-28 99.0 0.0 3.4e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase R3H PF01424.22 EGB05345.1 - 0.00052 19.9 0.0 0.0017 18.3 0.0 1.9 1 0 0 1 1 1 1 R3H domain Pkinase PF00069.25 EGB05347.1 - 1.1e-67 228.2 0.0 1.2e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05347.1 - 1.7e-31 109.5 0.0 1.9e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB05347.1 - 7.5e-06 25.4 0.0 1.6e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB05347.1 - 3.2e-05 23.4 0.0 8.6e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB05347.1 - 8.1e-05 21.6 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB05347.1 - 0.00022 21.2 0.0 0.00053 20.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family GFO_IDH_MocA PF01408.22 EGB05348.1 - 1.6e-23 83.8 0.1 2.3e-23 83.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGB05348.1 - 1.1e-05 25.4 0.0 3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1843 PF08898.10 EGB05348.1 - 0.066 13.7 0.4 16 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Chloroa_b-bind PF00504.21 EGB05349.1 - 3.7e-26 92.6 0.1 4.8e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Anp1 PF03452.14 EGB05350.1 - 3.5e-38 131.5 0.0 6.4e-38 130.7 0.0 1.3 1 1 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EGB05350.1 - 0.027 14.3 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Pkinase PF00069.25 EGB05351.1 - 5.7e-43 147.2 0.0 6.3e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05351.1 - 2.5e-18 66.3 0.0 2.7e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05351.1 - 3.2e-05 23.4 0.0 6.9e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGB05351.1 - 0.00034 20.6 5.5 0.061 13.2 0.8 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB05351.1 - 0.086 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RbsD_FucU PF05025.13 EGB05352.1 - 1.5e-28 99.9 0.0 1.7e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 RbsD / FucU transport protein family DUF2470 PF10615.9 EGB05353.1 - 7.6e-16 58.5 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyrid_oxidase_2 PF13883.6 EGB05353.1 - 4.6e-13 49.5 0.0 8.3e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EGB05353.1 - 4.1e-06 26.9 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ABC_trans_aux PF03886.13 EGB05353.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component MIP PF00230.20 EGB05354.1 - 1.9e-24 86.7 2.1 2.7e-19 69.8 0.7 2.0 1 1 1 2 2 2 2 Major intrinsic protein Peptidase_C13 PF01650.18 EGB05355.1 - 4.7e-99 331.1 0.3 6e-99 330.7 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family Radical_SAM PF04055.21 EGB05356.1 - 3.6e-26 92.5 0.0 6e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EGB05356.1 - 9.8e-24 83.3 0.0 1.7e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EGB05356.1 - 0.00033 20.6 0.1 0.00077 19.4 0.1 1.6 1 0 0 1 1 1 1 TRAM domain PAE PF03283.13 EGB05357.1 - 8.5e-38 130.4 0.2 1.1e-37 130.0 0.2 1.1 1 0 0 1 1 1 1 Pectinacetylesterase ADH_zinc_N PF00107.26 EGB05358.1 - 1.2e-13 51.2 0.1 1.2e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGB05358.1 - 2.8e-07 31.6 0.2 6e-07 30.6 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGB05358.1 - 0.0035 16.8 0.2 0.0052 16.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EGB05358.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 EGB05358.1 - 0.012 15.5 0.3 0.02 14.8 0.3 1.4 1 0 0 1 1 1 0 KR domain ADH_N PF08240.12 EGB05358.1 - 0.032 14.1 0.1 2 8.3 0.1 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 EGB05358.1 - 0.066 12.9 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TPR_14 PF13428.6 EGB05358.1 - 0.93 10.5 4.1 0.46 11.5 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BOP1NT PF08145.12 EGB05359.1 - 2.3e-80 270.3 0.0 2.9e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGB05359.1 - 1.7e-17 63.5 5.6 0.0089 16.9 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05359.1 - 6.4e-07 29.6 0.0 0.4 11.0 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain GST_C_2 PF13410.6 EGB05360.1 - 6.5e-08 32.5 0.2 6.5e-08 32.5 0.2 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB05360.1 - 1.6e-07 31.6 0.0 3.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB05360.1 - 2e-06 28.0 0.0 4.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB05360.1 - 0.0028 17.8 0.0 0.022 15.0 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGB05360.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin DEAD PF00270.29 EGB05361.1 - 1.1e-41 142.6 0.0 3e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB05361.1 - 3e-23 82.3 0.0 1.2e-21 77.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB05361.1 - 0.0059 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Semialdhyde_dhC PF02774.18 EGB05362.1 - 3.8e-41 141.2 0.0 2.3e-40 138.7 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EGB05362.1 - 3.9e-22 79.0 0.0 6.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGB05362.1 - 0.064 13.9 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HOOK PF05622.12 EGB05363.1 - 0.56 8.3 5.4 0.76 7.8 5.4 1.0 1 0 0 1 1 1 0 HOOK protein COPIIcoated_ERV PF07970.12 EGB05364.1 - 4.1e-65 219.7 0.0 5.1e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGB05364.1 - 8.2e-15 54.9 0.1 1.9e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ABC1 PF03109.16 EGB05365.1 - 4e-29 101.2 0.0 8.7e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family TylF PF05711.11 EGB05366.1 - 2.1e-41 141.9 0.0 4.3e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EGB05366.1 - 2.8e-11 44.4 0.1 2.8e-11 44.4 0.1 3.8 3 2 0 3 3 3 1 Methyltransferase domain TPR_2 PF07719.17 EGB05366.1 - 0.00011 22.1 0.3 0.00088 19.2 0.3 2.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05366.1 - 0.0046 16.7 0.1 0.013 15.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat LXG PF04740.12 EGB05366.1 - 0.072 12.8 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF919 PF06034.11 EGB05366.1 - 0.088 12.6 2.2 0.19 11.6 2.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Mito_fiss_reg PF05308.11 EGB05366.1 - 0.17 12.0 0.5 0.3 11.1 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator BRE PF06113.12 EGB05366.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) DASH_Ask1 PF08655.10 EGB05366.1 - 0.21 11.5 0.2 0.39 10.6 0.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Ask1 OmpH PF03938.14 EGB05366.1 - 0.75 10.1 9.3 0.66 10.3 0.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SRCR PF00530.18 EGB05367.1 - 1.7e-09 38.1 0.8 3.6e-09 37.0 0.8 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Methyltr_RsmB-F PF01189.17 EGB05368.1 - 1.9e-65 220.3 0.0 2.7e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGB05368.1 - 1.1e-08 35.4 0.0 2.7e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF PCMT PF01135.19 EGB05368.1 - 0.0025 17.6 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EGB05368.1 - 0.0049 17.0 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase CCAP PF11105.8 EGB05368.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Pkinase PF00069.25 EGB05369.1 - 2.6e-36 125.4 0.0 1.9e-35 122.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05369.1 - 4.4e-18 65.5 0.0 9.1e-10 38.2 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EGB05369.1 - 6.7e-06 26.4 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 EGB05369.1 - 0.23 10.7 0.0 2.3 7.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Trefoil PF00088.18 EGB05371.1 - 0.7 9.8 13.5 0.98 9.4 3.0 2.3 1 1 1 2 2 2 0 Trefoil (P-type) domain GN3L_Grn1 PF08701.11 EGB05371.1 - 1.4 9.1 11.6 1.1 9.4 4.6 2.2 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Peptidase_M14 PF00246.24 EGB05372.1 - 5.1e-14 52.8 0.0 7.2e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CHORD PF04968.12 EGB05374.1 - 2.8e-40 136.8 31.1 2.8e-20 72.8 13.6 2.3 2 0 0 2 2 2 2 CHORD Granulin PF00396.18 EGB05374.1 - 5 7.6 11.5 6.7 7.1 0.2 3.1 3 0 0 3 3 3 0 Granulin tRNA-synt_2 PF00152.20 EGB05375.1 - 3.1e-68 230.2 0.0 3.8e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGB05375.1 - 2.2e-05 24.4 0.1 3.8e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EGB05375.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain COesterase PF00135.28 EGB05376.1 - 4.9e-53 180.8 0.0 5.7e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGB05376.1 - 5e-11 42.9 3.0 1.3e-06 28.4 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB05376.1 - 0.003 17.1 0.0 0.0094 15.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family UFD1 PF03152.14 EGB05377.1 - 4.3e-13 49.1 0.0 8.9e-13 48.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 SAP PF02037.27 EGB05378.1 - 1.7e-12 46.8 1.4 4.5e-12 45.4 1.4 1.8 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EGB05378.1 - 0.012 15.3 1.0 0.03 14.0 0.0 2.3 2 0 0 2 2 2 0 HeH/LEM domain U79_P34 PF03064.16 EGB05378.1 - 0.73 9.1 12.7 1.1 8.5 12.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Telomere_Sde2_2 PF13297.6 EGB05378.1 - 0.78 9.4 7.1 0.19 11.4 0.5 2.8 2 1 1 3 3 3 0 Telomere stability C-terminal CDC27 PF09507.10 EGB05378.1 - 1.7 7.9 19.2 1.9 7.8 19.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Tho1_MOS11_C PF18592.1 EGB05378.1 - 1.8 8.4 29.9 0.11 12.3 6.3 4.8 3 1 3 6 6 6 0 Tho1/MOS11 C-terminal domain TspO_MBR PF03073.15 EGB05379.1 - 6.9e-17 61.8 6.1 6.9e-17 61.8 6.1 1.7 2 0 0 2 2 2 1 TspO/MBR family TIM PF00121.18 EGB05380.1 - 1.3e-82 276.8 0.1 1.7e-82 276.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CS PF04969.16 EGB05381.1 - 0.026 15.5 0.0 6.9 7.8 0.0 2.4 2 0 0 2 2 2 0 CS domain FeoA PF04023.14 EGB05382.1 - 0.099 12.9 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 FeoA domain TMF_DNA_bd PF12329.8 EGB05382.1 - 0.2 11.7 1.4 0.34 10.9 0.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 EGB05382.1 - 8.3 6.7 6.2 5.9 7.2 0.2 3.3 3 1 0 3 3 3 0 ABC transporter C-terminal domain EF-hand_7 PF13499.6 EGB05383.1 - 2.6e-10 40.6 5.6 0.0029 18.0 0.1 4.7 3 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EGB05383.1 - 2.4e-05 23.9 2.4 1.7 8.8 0.0 5.1 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.32 EGB05383.1 - 9.9e-05 21.6 5.0 0.93 9.2 0.0 4.8 6 0 0 6 6 6 2 EF hand EF-hand_13 PF17958.1 EGB05383.1 - 0.00022 20.9 0.1 0.19 11.6 0.0 3.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EGB05383.1 - 0.12 11.9 0.3 4.6 6.9 0.1 2.9 2 0 0 2 2 2 0 EF hand TraY PF05509.11 EGB05383.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 TraY domain SCAB-ABD PF16711.5 EGB05383.1 - 0.14 12.0 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Scramblase PF03803.15 EGB05384.1 - 9.9e-43 146.0 0.0 1.3e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Scramblase TetR_C_31 PF17940.1 EGB05385.1 - 0.012 15.8 2.9 0.012 15.8 2.9 2.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Lung_7-TM_R PF06814.13 EGB05386.1 - 7.9e-40 136.9 8.0 9.4e-40 136.7 8.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF2569 PF10754.9 EGB05386.1 - 2.2 8.7 15.3 0.23 11.9 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) COPIIcoated_ERV PF07970.12 EGB05387.1 - 1.7e-26 93.4 0.1 3.3e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGB05387.1 - 1.7e-23 82.8 0.0 3.2e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 EGB05387.1 - 4.6e-20 71.5 0.0 7.9e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB05387.1 - 4.1e-06 27.2 0.0 8.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGB05387.1 - 8.7e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGB05387.1 - 0.0077 16.4 0.3 0.036 14.2 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EGB05387.1 - 0.045 13.7 0.1 0.16 11.9 0.1 1.7 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EGB05387.1 - 0.083 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like PhoLip_ATPase_C PF16212.5 EGB05388.1 - 4.5e-55 187.1 12.5 4.5e-55 187.1 12.5 2.4 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGB05388.1 - 9.9e-14 50.8 0.5 9.9e-14 50.8 0.5 2.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGB05388.1 - 4.6e-10 40.2 0.2 0.001 19.4 0.1 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGB05388.1 - 2e-07 31.0 0.0 1.1e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGB05388.1 - 0.00077 19.0 0.0 0.0025 17.4 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGB05388.1 - 0.042 13.6 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DEAD PF00270.29 EGB05389.1 - 2.6e-09 37.1 0.0 8.6e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB05389.1 - 8.9e-08 32.5 0.0 2.5e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CarD_CdnL_TRCF PF02559.16 EGB05389.1 - 0.012 16.3 0.0 0.034 14.9 0.0 1.8 1 1 0 1 1 1 0 CarD-like/TRCF domain ResIII PF04851.15 EGB05389.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Carboxyl_trans PF01039.22 EGB05390.1 - 1.9e-79 267.6 2.0 2.8e-79 267.0 2.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGB05390.1 - 8.7e-45 152.8 0.1 6e-44 150.1 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGB05390.1 - 5.5e-29 100.9 0.1 2.8e-28 98.7 0.1 2.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGB05390.1 - 3.2e-21 75.4 0.0 1.6e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGB05390.1 - 5.6e-11 42.1 2.7 1.3e-10 41.0 2.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EGB05390.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ECH_1 PF00378.20 EGB05390.1 - 0.017 14.4 1.0 0.037 13.3 1.0 1.5 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ATPgrasp_Ter PF15632.6 EGB05390.1 - 0.03 14.1 0.3 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon HlyD_3 PF13437.6 EGB05390.1 - 0.074 13.8 3.2 0.14 12.9 0.3 2.7 2 0 0 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EGB05390.1 - 0.13 12.1 3.1 0.13 12.1 0.2 2.5 3 0 0 3 3 3 0 Biotin-lipoyl like HSF_DNA-bind PF00447.17 EGB05391.1 - 2.8e-10 40.7 0.0 0.0001 22.8 0.1 2.3 2 0 0 2 2 2 2 HSF-type DNA-binding CRAL_TRIO PF00650.20 EGB05392.1 - 2e-29 102.4 0.0 2.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain zf-RING_2 PF13639.6 EGB05392.1 - 9.6e-07 29.0 6.5 2e-06 28.0 6.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGB05392.1 - 1.3e-06 28.3 4.4 3.3e-06 27.0 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGB05392.1 - 2.3e-05 24.1 5.8 4.1e-05 23.4 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB05392.1 - 3.2e-05 23.7 7.9 6.6e-05 22.7 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGB05392.1 - 8.7e-05 22.3 5.4 0.00017 21.4 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGB05392.1 - 0.00016 21.7 7.1 0.00031 20.8 7.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGB05392.1 - 0.00087 19.2 6.0 0.002 18.0 6.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGB05392.1 - 0.003 17.4 8.0 0.037 13.9 8.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 CRAL_TRIO_2 PF13716.6 EGB05392.1 - 0.0044 17.2 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-RING_6 PF14835.6 EGB05392.1 - 0.014 15.2 4.7 0.03 14.2 4.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Elf1 PF05129.13 EGB05392.1 - 0.027 14.5 0.6 0.075 13.1 0.2 2.0 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-ANAPC11 PF12861.7 EGB05392.1 - 0.076 13.1 1.9 0.14 12.2 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGB05392.1 - 0.077 12.8 4.9 0.26 11.1 4.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf_C2HC_14 PF18574.1 EGB05392.1 - 0.087 12.6 2.0 0.18 11.6 2.0 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain zf-rbx1 PF12678.7 EGB05392.1 - 0.12 12.7 7.5 0.04 14.2 4.4 1.8 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EGB05392.1 - 0.95 9.6 5.3 1.9 8.7 5.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 UIM PF02809.20 EGB05392.1 - 6.1 7.0 13.5 0.071 13.1 3.3 3.1 2 0 0 2 2 2 0 Ubiquitin interaction motif GSHPx PF00255.19 EGB05393.1 - 6.6e-05 22.4 0.0 8.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase LCAT PF02450.15 EGB05396.1 - 3.1e-47 161.6 0.0 5.7e-47 160.7 0.0 1.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF3523 PF12037.8 EGB05397.1 - 1e-29 103.7 19.3 1.6e-29 103.1 19.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 EGB05397.1 - 1.9e-22 80.1 0.0 5.1e-22 78.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGB05397.1 - 5.6e-06 26.2 0.1 1.4e-05 24.9 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB05397.1 - 6.1e-05 23.3 3.0 0.055 13.7 0.0 3.6 2 1 2 4 4 4 2 AAA domain Zot PF05707.12 EGB05397.1 - 0.0002 21.0 0.1 0.009 15.7 0.0 2.6 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) NACHT PF05729.12 EGB05397.1 - 0.0012 18.8 0.0 0.6 10.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_11 PF13086.6 EGB05397.1 - 0.004 17.0 6.4 0.59 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB05397.1 - 0.0077 16.4 4.3 0.01 16.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB05397.1 - 0.0078 16.6 0.0 0.0078 16.6 0.0 3.9 3 2 1 4 4 3 1 AAA ATPase domain TsaE PF02367.17 EGB05397.1 - 0.01 15.8 0.4 0.024 14.6 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGB05397.1 - 0.013 14.9 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGB05397.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB05397.1 - 0.02 15.3 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EGB05397.1 - 0.028 13.9 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGB05397.1 - 0.035 14.7 0.1 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGB05397.1 - 0.058 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EGB05397.1 - 0.061 13.8 0.2 0.061 13.8 0.2 3.1 2 2 0 2 2 2 0 AAA domain ATPase PF06745.13 EGB05397.1 - 0.09 12.1 0.0 0.28 10.5 0.0 1.9 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.11 EGB05397.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGB05397.1 - 0.18 12.0 0.0 0.18 12.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.7 EGB05398.1 - 7.1e-29 100.2 13.3 1.5e-11 44.8 1.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB05398.1 - 2.3e-24 85.4 6.0 2.1e-10 40.9 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB05398.1 - 5.4e-23 78.6 5.2 3.7e-06 26.9 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EGB05398.1 - 4.7e-17 61.8 10.2 1.7e-10 40.9 0.8 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB05398.1 - 1.1e-15 57.3 11.5 1.4e-07 31.7 0.4 5.1 5 0 0 5 5 5 4 Ankyrin repeat tRNA-synt_1 PF00133.22 EGB05399.1 - 2.6e-183 610.5 0.0 2.6e-182 607.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGB05399.1 - 7.5e-34 116.9 0.0 1.7e-33 115.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA EF1_GNE PF00736.19 EGB05399.1 - 1.7e-18 66.5 3.0 1.8e-18 66.5 1.4 2.0 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain tRNA-synt_1g PF09334.11 EGB05399.1 - 3.3e-14 52.5 0.6 2.2e-07 30.0 0.0 4.1 4 0 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 EGB05399.1 - 1.4e-11 44.5 4.2 1.4e-11 44.5 4.2 3.6 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm WHEP-TRS PF00458.20 EGB05399.1 - 0.00011 22.3 4.5 0.00011 22.3 4.5 3.2 4 0 0 4 4 4 1 WHEP-TRS domain tRNA-synt_1_2 PF13603.6 EGB05399.1 - 0.0002 21.0 0.0 0.00066 19.2 0.0 1.9 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGB05399.1 - 0.0014 18.0 0.0 0.089 12.1 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain EF-hand_1 PF00036.32 EGB05400.1 - 2.5e-15 54.8 0.3 0.0073 15.8 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB05400.1 - 6.5e-15 55.3 0.0 2.1e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB05400.1 - 7.6e-12 44.2 1.1 0.017 15.0 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGB05400.1 - 1e-10 40.6 4.0 0.032 13.7 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGB05400.1 - 2.1e-08 33.9 0.7 0.68 9.8 0.2 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 EGB05400.1 - 0.01 15.8 0.5 1.8 8.6 0.2 3.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF5372 PF17342.2 EGB05400.1 - 0.055 13.9 0.2 0.17 12.3 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5372) Myb_DNA-binding PF00249.31 EGB05401.1 - 4.2e-39 132.5 3.8 1.9e-17 63.1 0.1 3.3 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB05401.1 - 7.2e-33 112.6 0.0 6.5e-12 45.5 0.1 3.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGB05401.1 - 0.00019 21.4 0.0 4.4 7.4 0.0 3.4 2 1 0 3 3 3 2 SLIDE Rap1_C PF11626.8 EGB05401.1 - 0.00021 21.3 1.1 2.6 8.2 0.2 3.2 2 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EGB05401.1 - 0.00049 19.9 0.0 0.0034 17.3 0.0 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Aminotran_1_2 PF00155.21 EGB05402.1 - 1.4e-57 195.6 0.0 1.5e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGB05402.1 - 0.0013 18.2 0.3 0.0019 17.6 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family XylR_N PF06505.11 EGB05403.1 - 0.0037 17.0 0.5 0.0084 15.8 0.1 1.8 2 0 0 2 2 2 1 Activator of aromatic catabolism TPR_4 PF07721.14 EGB05403.1 - 0.032 14.8 1.0 0.032 14.8 1.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05403.1 - 0.3 11.8 5.3 8.2 7.3 0.8 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGB05403.1 - 0.74 9.5 12.0 1.4 8.6 6.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain EGF_alliinase PF04863.13 EGB05403.1 - 1.8 9.0 4.3 3.8 8.0 0.2 2.3 2 0 0 2 2 2 0 Alliinase EGF-like domain TPR_20 PF14561.6 EGB05403.1 - 5.7 7.4 8.7 57 4.1 5.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Hydrolase PF00702.26 EGB05404.1 - 3.3e-20 73.3 1.6 3.9e-12 46.9 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGB05404.1 - 1e-16 61.0 0.1 4.6e-15 55.6 0.1 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGB05404.1 - 0.0037 17.0 0.1 0.0087 15.8 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB05404.1 - 0.045 14.2 1.5 0.79 10.1 1.0 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGB05404.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) TPP_enzyme_M PF00205.22 EGB05404.1 - 0.12 12.1 1.3 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF2465 PF10239.9 EGB05405.1 - 1.6e-31 109.7 0.0 6e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2465) EF-hand_1 PF00036.32 EGB05406.1 - 1.1e-72 234.3 29.4 0.00016 20.9 0.0 16.8 17 0 0 17 17 17 16 EF hand EF-hand_7 PF13499.6 EGB05406.1 - 4.3e-69 228.9 24.2 4e-10 40.0 0.0 9.8 9 1 1 10 10 10 9 EF-hand domain pair EF-hand_6 PF13405.6 EGB05406.1 - 2.2e-65 211.1 14.6 0.00036 20.2 0.0 16.8 17 0 0 17 17 16 14 EF-hand domain EF-hand_5 PF13202.6 EGB05406.1 - 3.6e-33 111.6 24.1 0.0077 15.7 0.2 14.8 15 0 0 15 15 15 10 EF hand EF-hand_8 PF13833.6 EGB05406.1 - 1.7e-21 75.8 39.0 0.00014 21.6 0.1 14.9 12 5 5 17 17 17 7 EF-hand domain pair Aldo_ket_red PF00248.21 EGB05406.1 - 6.3e-18 65.0 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family EF-hand_4 PF12763.7 EGB05406.1 - 2.3e-12 46.7 34.2 0.59 10.1 0.0 14.6 9 6 5 15 15 15 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 EGB05406.1 - 0.00097 20.0 0.2 12 6.8 0.0 5.4 5 0 0 5 5 5 1 EF-hand domain Phage_FRD3 PF05798.11 EGB05406.1 - 0.047 14.0 0.0 21 5.5 0.0 3.8 4 0 0 4 4 4 0 Bacteriophage FRD3 protein SHOCT PF09851.9 EGB05406.1 - 0.063 13.0 1.1 42 4.0 0.0 3.7 3 0 0 3 3 3 0 Short C-terminal domain MazG_C PF18722.1 EGB05406.1 - 0.063 12.8 1.2 28 4.1 0.0 4.0 4 0 0 4 4 4 0 MazG C-terminal domain Sulfotransfer_4 PF17784.1 EGB05407.1 - 2.9e-10 40.3 0.7 1.5e-09 38.0 0.0 2.4 2 1 0 2 2 2 1 Sulfotransferase domain DUF445 PF04286.12 EGB05407.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Sulfotransfer_3 PF13469.6 EGB05407.1 - 0.046 14.1 9.2 0.13 12.6 0.1 3.6 2 2 1 4 4 4 0 Sulfotransferase family Catalase-rel PF06628.12 EGB05407.1 - 0.06 13.6 0.2 2.5 8.4 0.1 2.6 1 1 1 2 2 2 0 Catalase-related immune-responsive UBN_AB PF14075.6 EGB05407.1 - 0.16 11.7 2.6 2.2 8.0 0.1 2.4 1 1 1 2 2 2 0 Ubinuclein conserved middle domain REPA_OB_2 PF16900.5 EGB05408.1 - 1.3e-28 98.8 0.1 9.5e-28 96.0 0.1 2.1 2 0 0 2 2 2 1 Replication protein A OB domain Rep_fac-A_C PF08646.10 EGB05408.1 - 2.1e-22 79.5 3.0 3.8e-22 78.6 3.0 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 EGB05408.1 - 1.7e-07 31.1 0.2 1.4e-05 25.0 0.0 3.0 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain cNMP_binding PF00027.29 EGB05409.1 - 3e-31 107.3 0.2 8.2e-18 64.3 0.0 2.6 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGB05410.1 - 3.1e-58 197.2 0.0 3.6e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05410.1 - 6.8e-33 114.0 0.0 8.2e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGB05410.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGB05410.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB05410.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Spc7 PF08317.11 EGB05411.1 - 0.002 17.1 12.0 0.002 17.1 12.0 3.2 3 0 0 3 3 3 1 Spc7 kinetochore protein DUF1664 PF07889.12 EGB05411.1 - 0.17 11.9 4.4 4.7 7.3 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Vac_Fusion PF02346.16 EGB05411.1 - 1.2 8.8 3.5 13 5.5 0.1 2.7 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 FapA PF03961.13 EGB05411.1 - 2.7 6.5 6.1 0.33 9.5 1.9 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A XhlA PF10779.9 EGB05411.1 - 3.6 7.8 15.1 6.4 7.1 0.3 5.2 5 1 1 6 6 6 0 Haemolysin XhlA GST_N_3 PF13417.6 EGB05412.1 - 1.2e-13 51.2 0.0 3.1e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB05412.1 - 1.1e-09 38.4 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGB05412.1 - 4.8e-07 30.0 0.0 9.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EGB05412.1 - 0.009 16.7 0.0 0.016 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Mito_carr PF00153.27 EGB05413.1 - 4.8e-21 74.5 2.9 3.3e-08 33.4 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Pescadillo_N PF06732.11 EGB05414.1 - 1e-90 304.0 0.0 1.1e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Pescadillo N-terminus Lenti_VIF_2 PF07401.12 EGB05414.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein Pyr_excise PF03013.14 EGB05414.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase DUF3007 PF11460.8 EGB05415.1 - 6e-27 93.7 0.9 6.6e-27 93.6 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) ABC2_membrane_3 PF12698.7 EGB05415.1 - 0.012 14.8 4.0 0.015 14.4 4.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein LapA_dom PF06305.11 EGB05415.1 - 0.032 14.1 0.7 0.041 13.7 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 EGB05415.1 - 0.11 12.3 0.2 0.11 12.3 0.2 1.7 2 1 0 2 2 2 0 Vpu protein ASF1_hist_chap PF04729.13 EGB05416.1 - 4.1e-56 189.2 0.0 4.8e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Ank_2 PF12796.7 EGB05418.1 - 1.4e-31 108.9 1.7 2.4e-11 44.1 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB05418.1 - 3.6e-27 94.4 4.9 2.7e-12 46.9 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB05418.1 - 1e-23 83.1 7.2 1.2e-07 31.8 0.1 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 EGB05418.1 - 8.6e-22 77.7 11.2 2.1e-21 76.4 11.2 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase Ank PF00023.30 EGB05418.1 - 7e-20 70.5 2.1 9.1e-05 22.7 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EGB05418.1 - 5.6e-19 66.3 1.8 0.0019 18.5 0.1 6.3 5 0 0 5 5 5 4 Ankyrin repeat NAD_binding_8 PF13450.6 EGB05418.1 - 0.035 14.3 0.3 0.72 10.1 0.0 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Tim17 PF02466.19 EGB05419.1 - 1.6e-23 83.2 11.7 1.8e-23 83.1 11.7 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 EGB05419.1 - 0.34 11.3 14.2 0.12 12.8 7.7 2.6 1 1 2 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.6 EGB05419.1 - 1.5 8.6 16.6 0.38 10.5 2.5 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper ACP_syn_III PF08545.10 EGB05420.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MCM PF00493.23 EGB05423.1 - 9.8e-98 325.7 0.2 1.4e-97 325.2 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGB05423.1 - 1.4e-23 83.1 0.5 4.1e-23 81.6 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EGB05423.1 - 2.7e-21 75.7 0.1 4.7e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EGB05423.1 - 0.00022 20.7 0.0 0.0016 17.9 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RcpC PF16976.5 EGB05423.1 - 0.0021 18.1 0.2 0.0061 16.6 0.0 1.9 2 0 0 2 2 2 1 Flp pilus assembly protein RcpC/CpaB AAA_5 PF07728.14 EGB05423.1 - 0.0063 16.5 0.0 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB05423.1 - 0.0065 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49_C PF17856.1 EGB05423.1 - 0.056 13.6 0.2 0.19 11.9 0.1 2.0 2 0 0 2 2 2 0 TIP49 AAA-lid domain Vps16_C PF04840.12 EGB05424.1 - 1.5e-44 152.3 0.8 2.2e-44 151.8 0.8 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 EGB05424.1 - 5.2e-12 45.2 0.2 8.8e-12 44.5 0.2 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region PhoU PF01895.19 EGB05424.1 - 0.02 15.3 0.7 0.083 13.4 0.2 2.3 2 0 0 2 2 2 0 PhoU domain Spt5-NGN PF03439.13 EGB05427.1 - 6.5e-05 22.7 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 EGB05427.1 - 0.00073 19.4 6.5 2.7 8.1 0.0 4.7 4 0 0 4 4 4 2 KOW motif Spt5_N PF11942.8 EGB05427.1 - 0.02 15.9 14.9 0.02 15.9 14.9 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF3246 PF11596.8 EGB05427.1 - 0.071 12.5 3.0 0.18 11.2 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Tub_N PF16322.5 EGB05427.1 - 0.32 11.4 7.0 0.64 10.4 7.0 1.5 1 0 0 1 1 1 0 Tubby N-terminal EF-hand_7 PF13499.6 EGB05428.1 - 1.3e-24 86.4 6.2 2.8e-14 53.3 0.6 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB05428.1 - 3e-23 79.6 7.0 1e-05 24.7 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB05428.1 - 2.5e-20 70.6 4.8 0.0001 21.9 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB05428.1 - 7.5e-18 64.1 5.7 8e-07 28.8 0.3 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB05428.1 - 1.3e-15 56.1 6.4 0.00032 20.1 0.1 4.4 4 1 0 4 4 4 4 EF hand EF-hand_11 PF08976.11 EGB05428.1 - 1.1e-07 32.6 0.1 0.0047 17.8 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB05428.1 - 2.1e-06 28.0 0.4 0.029 14.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGB05428.1 - 4.2e-06 27.0 0.3 0.017 15.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 EGB05428.1 - 5.6e-05 22.9 8.9 0.001 18.8 2.0 3.4 2 2 2 4 4 4 3 EF hand EF-hand_4 PF12763.7 EGB05428.1 - 0.0022 17.9 1.0 0.4 10.6 0.0 2.4 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Rnk_N PF14760.6 EGB05428.1 - 0.018 15.5 0.5 0.045 14.2 0.0 1.9 2 0 0 2 2 2 0 Rnk N-terminus S-layer PF07752.11 EGB05428.1 - 0.071 12.2 0.9 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 S-layer protein S_100 PF01023.19 EGB05428.1 - 0.4 10.4 2.1 4.6 7.0 0.3 3.0 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain PP2C PF00481.21 EGB05429.1 - 1e-36 126.9 0.0 1.4e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB05429.1 - 0.00025 20.7 0.0 0.00046 19.9 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C Med9 PF07544.13 EGB05430.1 - 0.055 13.6 0.4 0.34 11.0 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-SNAP50_C PF12251.8 EGB05431.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal RTP1_C1 PF10363.9 EGB05432.1 - 4.4e-20 72.0 0.0 1.3e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 EGB05432.1 - 0.02 15.3 0.0 0.02 15.3 0.0 3.2 4 1 0 4 4 4 0 HEAT repeats RTP1_C2 PF10304.9 EGB05432.1 - 0.073 12.8 0.3 0.25 11.1 0.3 2.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 HEAT PF02985.22 EGB05432.1 - 0.3 11.5 1.7 10 6.7 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat Pkinase PF00069.25 EGB05433.1 - 9.5e-54 182.5 0.0 1.7e-53 181.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05433.1 - 1.8e-24 86.4 0.0 9.2e-23 80.8 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05433.1 - 0.019 14.9 0.0 0.065 13.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGB05433.1 - 0.02 14.3 0.1 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB05433.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APG6_N PF17675.1 EGB05434.1 - 0.0041 17.6 13.0 0.0041 17.6 13.0 8.4 2 2 5 7 7 7 5 Apg6 coiled-coil region TolA_bind_tri PF16331.5 EGB05434.1 - 0.0043 17.1 0.2 0.0043 17.1 0.2 10.9 8 4 3 11 11 11 1 TolA binding protein trimerisation YwqJ-deaminase PF14431.6 EGB05434.1 - 0.05 13.8 9.7 0.077 13.2 5.4 3.2 1 1 1 2 2 2 0 YwqJ-like deaminase LRR_6 PF13516.6 EGB05435.1 - 0.002 18.0 0.7 0.7 10.1 0.1 2.7 2 0 0 2 2 2 2 Leucine Rich repeat LAL_C2 PF18603.1 EGB05435.1 - 0.12 12.6 1.1 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 WD40 PF00400.32 EGB05436.1 - 7.1e-38 127.9 65.5 0.08 13.9 0.0 25.0 27 0 0 27 27 27 12 WD domain, G-beta repeat HELP PF03451.14 EGB05436.1 - 7.8e-28 96.1 0.0 7.7e-17 60.9 0.0 2.6 2 0 0 2 2 2 2 HELP motif ANAPC4_WD40 PF12894.7 EGB05436.1 - 9.5e-19 67.5 0.0 1.3 9.3 0.0 12.5 11 4 2 13 13 13 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGB05436.1 - 7.3e-06 25.8 0.0 1.8 8.6 0.0 6.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGB05436.1 - 0.00012 21.2 0.4 1.5 7.7 0.0 5.2 6 0 0 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_7 PF13499.6 EGB05436.1 - 0.00023 21.6 0.6 0.021 15.2 0.5 2.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EGB05436.1 - 0.0062 16.4 1.1 0.033 14.0 0.4 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB05436.1 - 0.084 12.9 0.2 0.7 10.0 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EGB05436.1 - 0.2 11.3 0.3 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 EGB05437.1 - 6.4e-10 38.7 0.4 1.3e-09 37.7 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 EGB05437.1 - 5.7e-07 29.9 0.8 2.2e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB05437.1 - 9.2e-05 21.7 0.3 0.00044 19.6 0.2 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB05437.1 - 0.022 14.7 1.3 1.4 9.1 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain DUF4201 PF13870.6 EGB05438.1 - 3.1e-40 137.8 24.2 3.1e-40 137.8 24.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) SecD-TM1 PF13721.6 EGB05438.1 - 0.037 14.5 1.0 0.037 14.5 1.0 3.0 1 1 1 3 3 3 0 SecD export protein N-terminal TM region MazG PF03819.17 EGB05438.1 - 0.51 10.6 6.3 2 8.7 2.2 3.2 2 1 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Biotin_lipoyl_2 PF13533.6 EGB05438.1 - 0.99 9.3 4.5 2.9 7.8 0.1 2.8 3 0 0 3 3 3 0 Biotin-lipoyl like MscS_porin PF12795.7 EGB05438.1 - 2.5 7.6 30.6 0.025 14.1 7.6 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain COG5 PF10392.9 EGB05438.1 - 4.4 7.5 16.0 0.89 9.7 6.0 3.2 2 1 2 4 4 4 0 Golgi transport complex subunit 5 LegC3_N PF18654.1 EGB05438.1 - 5.8 6.1 28.6 0.076 12.2 11.8 2.2 1 1 0 2 2 2 0 LegC3 N-terminal coiled-coil domain DUF948 PF06103.11 EGB05438.1 - 8.1 6.8 9.0 19 5.6 0.7 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 EGB05438.1 - 9.3 6.6 32.3 3.2 8.2 18.9 2.9 1 1 1 2 2 2 0 Fez1 p25-alpha PF05517.12 EGB05440.1 - 0.081 13.1 0.1 0.29 11.3 0.1 1.9 1 0 0 1 1 1 0 p25-alpha zf-B_box PF00643.24 EGB05440.1 - 0.15 12.2 4.6 0.38 10.9 4.6 1.7 1 0 0 1 1 1 0 B-box zinc finger zf-HIT PF04438.16 EGB05440.1 - 5.8 6.9 10.2 16 5.5 10.2 1.7 1 0 0 1 1 1 0 HIT zinc finger SHIPPO-rpt PF07004.12 EGB05441.1 - 9.8e-05 23.1 27.6 11 7.1 0.2 8.6 8 0 0 8 8 8 7 Sperm-tail PG-rich repeat Adap_comp_sub PF00928.21 EGB05442.1 - 8.7e-91 303.9 0.0 1.1e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGB05442.1 - 2.9e-05 24.0 1.5 4.9e-05 23.3 1.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 EGB05442.1 - 0.028 14.4 0.3 0.089 12.8 0.3 1.9 1 1 0 1 1 1 0 Regulated-SNARE-like domain muHD PF10291.9 EGB05442.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain CK_II_beta PF01214.18 EGB05443.1 - 1.3e-77 259.8 0.0 1.5e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit MORN PF02493.20 EGB05444.1 - 1.8e-34 115.5 60.0 3.9e-06 26.4 0.3 10.6 10 1 0 10 10 10 10 MORN repeat HTH_33 PF13592.6 EGB05445.1 - 0.0019 17.8 0.1 0.0075 15.9 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 EGB05445.1 - 0.02 15.5 0.9 0.02 15.5 0.9 2.1 3 0 0 3 3 3 0 Homeodomain-like domain CSD PF00313.22 EGB05446.1 - 3.1e-09 36.6 1.0 3.7e-09 36.3 1.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain FKBP_C PF00254.28 EGB05447.1 - 2.3e-23 82.3 0.0 2.5e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L26 PF16906.5 EGB05448.1 - 4.4e-37 126.4 4.0 5.3e-37 126.1 4.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGB05448.1 - 4.6e-06 26.4 1.0 9.6e-06 25.4 1.0 1.5 1 0 0 1 1 1 1 KOW motif Pkinase PF00069.25 EGB05449.1 - 8.8e-63 212.1 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05449.1 - 1.1e-28 100.2 0.6 1.9e-28 99.5 0.6 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB05449.1 - 2e-05 23.7 0.5 3.3e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGB05449.1 - 0.00012 21.0 0.1 0.00026 19.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGB05449.1 - 0.0024 17.3 0.1 0.0043 16.4 0.1 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB05449.1 - 0.0044 17.0 0.1 0.11 12.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGB05449.1 - 0.042 13.5 0.1 0.33 10.5 0.0 2.2 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MORN PF02493.20 EGB05450.1 - 1.7e-27 93.7 56.0 5.5e-06 26.0 1.3 11.6 12 0 0 12 12 12 8 MORN repeat HCV_NS5a_1a PF08300.13 EGB05450.1 - 5.6 7.2 10.4 2.3 8.4 0.1 4.1 3 1 2 5 5 5 0 Hepatitis C virus non-structural 5a zinc finger domain Ras PF00071.22 EGB05451.1 - 6.8e-26 90.8 0.0 7.9e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB05451.1 - 1.4e-17 64.1 0.0 2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB05451.1 - 1e-07 31.6 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGB05451.1 - 0.00035 20.2 0.0 0.0011 18.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EGB05451.1 - 0.05 12.6 0.0 0.069 12.1 0.0 1.3 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Topoisom_I PF01028.20 EGB05452.1 - 1.3e-84 283.0 4.6 2.5e-84 282.1 4.6 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGB05452.1 - 2e-75 253.0 0.0 2e-75 253.0 0.0 2.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGB05452.1 - 4.3e-24 84.2 0.1 1.1e-23 82.9 0.1 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain SDH_C PF18317.1 EGB05452.1 - 0.085 12.7 0.3 0.22 11.3 0.3 1.8 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain PAH PF02671.21 EGB05453.1 - 5.1e-19 68.1 0.1 9.7e-19 67.3 0.1 1.4 1 1 1 2 2 2 1 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EGB05454.1 - 7e-27 93.4 0.1 1.5e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 EGB05454.1 - 1e-20 73.6 3.3 1.8e-20 72.8 3.3 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat B56 PF01603.20 EGB05455.1 - 1.3e-165 551.4 4.6 1.5e-165 551.2 4.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) AIG1 PF04548.16 EGB05455.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Coatomer_WDAD PF04053.14 EGB05456.1 - 3.5e-113 379.0 0.0 5.2e-113 378.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EGB05456.1 - 8.6e-104 347.5 0.0 1.3e-103 346.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EGB05456.1 - 2.1e-43 145.4 18.1 4.2e-08 33.7 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05456.1 - 5.9e-10 39.3 1.6 0.00016 21.9 0.1 5.6 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGB05456.1 - 0.042 12.6 1.0 0.74 8.5 0.1 3.0 3 1 1 4 4 4 0 Nup133 N terminal like Nup160 PF11715.8 EGB05456.1 - 0.28 9.8 7.2 1.2 7.7 0.1 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Sec63 PF02889.16 EGB05457.1 - 1.1e-24 86.9 0.0 2e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 EGB05457.1 - 8.5e-23 80.3 1.3 1.4e-22 79.6 0.5 1.8 2 0 0 2 2 2 1 DnaJ domain Tctex-1 PF03645.13 EGB05458.1 - 2.7e-18 66.1 0.0 3e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Pkip-1 PF06878.11 EGB05458.1 - 0.037 14.1 0.0 0.043 13.9 0.0 1.0 1 0 0 1 1 1 0 Pkip-1 protein Ins145_P3_rec PF08709.11 EGB05459.1 - 1.7e-16 60.1 0.0 3e-07 29.9 0.0 3.3 3 0 0 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 EGB05459.1 - 2.4e-06 27.3 0.0 5.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 EGB05459.1 - 5.4e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 RIH domain Collagen PF01391.18 EGB05459.1 - 0.0011 18.6 12.4 0.0011 18.6 12.4 2.9 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) MIR PF02815.19 EGB05459.1 - 0.0014 18.5 0.0 0.021 14.7 0.0 2.3 2 0 0 2 2 2 1 MIR domain ETC_C1_NDUFA4 PF04800.12 EGB05460.1 - 4.6e-25 87.7 1.0 5.2e-25 87.5 1.0 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region GHMP_kinases_N PF00288.26 EGB05461.1 - 1.9e-06 28.0 5.4 4.6e-06 26.8 5.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cullin PF00888.22 EGB05462.1 - 3.4e-198 660.2 1.0 4.4e-198 659.8 1.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGB05462.1 - 1.5e-27 95.4 0.6 4.4e-27 93.9 0.6 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.11 EGB05462.1 - 0.018 15.0 0.2 0.069 13.1 0.1 2.0 1 1 1 2 2 2 0 HbrB-like Penicillinase_R PF03965.16 EGB05462.1 - 0.057 13.8 0.1 0.55 10.6 0.0 2.7 2 0 0 2 2 2 0 Penicillinase repressor WAC_Acf1_DNA_bd PF10537.9 EGB05462.1 - 1.8 9.1 4.6 11 6.6 0.0 3.9 5 0 0 5 5 5 0 ATP-utilising chromatin assembly and remodelling N-terminal Glucokinase PF02685.16 EGB05463.1 - 7.7e-48 163.1 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Glucokinase Adaptin_N PF01602.20 EGB05464.1 - 6e-05 21.8 0.0 6.5e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF2451 PF10474.9 EGB05465.1 - 5.5e-20 72.2 0.0 5.9e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Kelch_3 PF13415.6 EGB05466.1 - 5.1e-34 115.9 24.8 2.3e-09 37.3 0.2 7.3 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 EGB05466.1 - 2.5e-29 101.0 16.3 9.2e-08 32.0 0.1 5.8 5 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB05466.1 - 6.1e-29 99.5 14.2 2.7e-05 24.0 0.1 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGB05466.1 - 3.4e-25 87.4 12.8 1.1e-05 24.9 0.0 6.2 5 2 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 EGB05466.1 - 2.8e-21 75.0 14.2 1.6e-05 25.0 0.1 5.9 4 3 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGB05466.1 - 8.5e-21 73.1 14.8 4.2e-05 23.3 0.2 6.3 6 0 0 6 6 6 5 Kelch motif RAG2 PF03089.14 EGB05466.1 - 8.7e-07 28.2 0.4 0.22 10.4 0.0 4.1 3 1 1 4 4 4 3 Recombination activating protein 2 EF-hand_8 PF13833.6 EGB05467.1 - 1.5e-10 40.8 0.1 3.7e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 EGB05467.1 - 4.4e-07 30.3 0.4 2.2e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB05467.1 - 9.4e-05 21.7 0.3 0.00063 19.1 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB05467.1 - 0.0014 18.4 1.0 0.34 11.0 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EGB05467.1 - 0.28 10.8 0.2 0.28 10.8 0.2 1.8 2 0 0 2 2 2 0 EF hand S1 PF00575.23 EGB05470.1 - 9.3e-31 106.0 0.7 6.5e-17 61.6 0.0 3.4 3 0 0 3 3 3 3 S1 RNA binding domain G-alpha PF00503.20 EGB05471.1 - 5.3e-102 341.6 6.0 7.5e-102 341.1 6.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGB05471.1 - 2.6e-14 53.1 1.6 7.1e-11 41.9 0.7 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB05471.1 - 0.0013 18.2 6.7 0.0051 16.2 1.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EGB05471.1 - 0.0056 16.4 0.1 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 EGB05471.1 - 0.13 12.5 3.6 4.2 7.6 0.0 3.3 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGB05471.1 - 0.14 12.3 0.2 9.9 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pkinase PF00069.25 EGB05472.1 - 3.6e-53 180.6 0.0 4.3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05472.1 - 1.3e-19 70.5 0.0 2.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB05472.1 - 2.6e-05 23.7 0.2 4.8e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB05472.1 - 0.0054 16.1 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGB05472.1 - 0.0082 15.8 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGB05472.1 - 0.023 13.5 0.2 0.045 12.5 0.2 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EGB05472.1 - 0.16 10.9 0.2 0.3 10.0 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Dynamin_M PF01031.20 EGB05473.1 - 2.4e-43 148.4 0.0 3.6e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGB05473.1 - 1.6e-37 129.1 0.0 2.8e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family PDZ_6 PF17820.1 EGB05473.1 - 2.8e-11 43.1 0.1 9.1e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EGB05473.1 - 4.7e-06 26.9 0.1 1.3e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 PDZ domain MMR_HSR1 PF01926.23 EGB05473.1 - 0.00012 22.2 0.2 0.0027 17.8 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EGB05473.1 - 0.00012 22.1 0.0 0.0003 20.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain PDZ_2 PF13180.6 EGB05473.1 - 0.00054 20.2 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EGB05473.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain CK_II_beta PF01214.18 EGB05474.1 - 3.3e-38 131.3 1.0 4e-38 131.1 1.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ribosomal_S13_N PF08069.12 EGB05475.1 - 3.6e-30 103.8 0.3 7.5e-30 102.8 0.3 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGB05475.1 - 1.1e-14 54.4 1.8 1.7e-14 53.8 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 FAE1_CUT1_RppA PF08392.12 EGB05476.1 - 4.3e-106 354.5 0.0 8.2e-106 353.5 0.0 1.5 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein FAT PF02259.23 EGB05476.1 - 1.3e-29 103.5 0.8 1.3e-29 103.5 0.8 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGB05476.1 - 3.3e-12 46.8 0.0 1.2e-11 44.9 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Chal_sti_synt_C PF02797.15 EGB05476.1 - 7.8e-12 45.4 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 EGB05476.1 - 6.8e-11 42.2 0.0 9.7e-10 38.5 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGB05476.1 - 0.00024 20.9 0.0 0.00069 19.4 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TIP120 PF08623.10 EGB05476.1 - 0.011 15.5 0.0 0.3 10.8 0.0 3.1 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) IFT46_B_C PF12317.8 EGB05476.1 - 0.045 13.5 0.3 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal RRM_1 PF00076.22 EGB05477.1 - 1.8e-13 50.1 0.0 0.00011 21.9 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GvpG PF05120.12 EGB05477.1 - 0.0098 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Nup35_RRM_2 PF14605.6 EGB05477.1 - 0.048 13.7 0.1 7.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGB05477.1 - 0.062 13.4 0.0 0.44 10.6 0.0 2.4 1 1 1 2 2 2 0 RNA binding motif GCV_T PF01571.21 EGB05477.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DMAP_binding PF06464.11 EGB05477.1 - 0.66 10.8 2.4 1.3 9.9 0.6 2.3 2 1 0 2 2 2 0 DMAP1-binding Domain TPR_1 PF00515.28 EGB05478.1 - 0.00031 20.4 0.1 0.055 13.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05478.1 - 0.0018 18.2 0.1 0.53 10.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat DHC_N1 PF08385.12 EGB05480.1 - 2.3e-32 112.4 0.4 2.5e-32 112.3 0.4 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Dynein_C PF18199.1 EGB05481.1 - 3.7e-50 170.9 0.0 4e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain UBA_5 PF16577.5 EGB05481.1 - 0.058 13.5 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 UBA domain Metallophos PF00149.28 EGB05482.1 - 1.8e-30 107.0 0.8 2.8e-30 106.3 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kinesin PF00225.23 EGB05483.1 - 7.3e-12 44.9 0.0 3.2e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGB05483.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding S4_2 PF13275.6 EGB05483.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 S4 domain Pkinase PF00069.25 EGB05484.1 - 3.8e-33 115.0 0.1 4.5e-33 114.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05484.1 - 2.5e-21 76.2 0.1 2.8e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05484.1 - 1.7e-06 28.2 0.1 0.0037 17.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB05484.1 - 0.00014 21.3 0.3 0.00016 21.1 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB05484.1 - 0.001 18.5 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGB05484.1 - 0.0063 16.1 0.2 0.0075 15.9 0.2 1.1 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGB05484.1 - 0.015 14.2 0.2 0.017 14.1 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF5319 PF17252.2 EGB05484.1 - 0.066 13.4 0.2 0.086 13.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5319) HECT PF00632.25 EGB05485.1 - 2.9e-85 286.5 0.0 4.3e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DnaJ_C PF01556.18 EGB05485.1 - 0.02 15.0 0.0 6.1 6.9 0.0 3.7 1 1 0 1 1 1 0 DnaJ C terminal domain NPCBM_assoc PF10633.9 EGB05485.1 - 0.11 12.8 0.1 11 6.4 0.1 3.3 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Adap_comp_sub PF00928.21 EGB05486.1 - 1.8e-24 86.6 0.0 2.4e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGB05486.1 - 4.4e-05 23.4 0.0 7.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Antimicrobial21 PF14861.6 EGB05487.1 - 0.00093 18.8 1.0 0.0024 17.5 1.0 1.8 1 0 0 1 1 1 1 Plant antimicrobial peptide Gtr1_RagA PF04670.12 EGB05488.1 - 1e-90 303.2 0.1 1.3e-90 302.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EGB05488.1 - 8.5e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EGB05488.1 - 1.6e-09 37.5 0.0 2.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGB05488.1 - 5.5e-09 36.3 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGB05488.1 - 6.3e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB05488.1 - 0.0097 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EGB05488.1 - 0.017 15.6 0.0 0.044 14.3 0.0 1.9 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EGB05488.1 - 0.023 14.4 0.1 0.084 12.6 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 EGB05488.1 - 0.026 13.7 0.9 3.1 6.9 0.0 2.4 1 1 0 2 2 2 0 G-protein alpha subunit DLIC PF05783.11 EGB05488.1 - 0.029 13.2 0.1 0.07 12.0 0.1 1.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 EGB05488.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB05488.1 - 0.13 12.1 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase FKBP_C PF00254.28 EGB05489.1 - 2.9e-29 101.2 0.0 3.4e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Metallophos PF00149.28 EGB05490.1 - 4.5e-35 122.0 0.0 6.2e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 EGB05491.1 - 1.7e-73 247.3 0.0 2.1e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05491.1 - 4.9e-34 117.8 0.0 6.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05491.1 - 0.00028 20.3 0.1 0.02 14.2 0.0 2.4 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGB05491.1 - 0.00047 19.2 0.0 0.0022 17.0 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB05491.1 - 0.026 14.4 0.0 0.085 12.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGB05491.1 - 0.17 11.3 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Clathrin PF00637.20 EGB05492.1 - 3.3e-09 36.8 9.2 2.6 7.9 0.0 7.5 5 1 3 8 8 8 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 EGB05492.1 - 7.2e-07 28.6 2.0 0.14 11.2 0.0 4.2 4 0 0 4 4 4 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 EGB05492.1 - 7.9e-07 29.3 0.2 2.1 8.7 0.0 6.1 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nic96 PF04097.14 EGB05492.1 - 1.9e-05 23.4 0.7 0.078 11.4 0.3 2.7 2 0 0 2 2 2 2 Nup93/Nic96 TPR_14 PF13428.6 EGB05492.1 - 0.0088 16.8 26.0 3.7 8.6 0.5 9.6 9 2 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05492.1 - 0.084 13.0 37.6 5.9 7.3 0.4 9.8 11 1 1 12 12 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05492.1 - 0.19 12.0 10.7 60 4.2 0.1 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Peptidase_C25_C PF03785.14 EGB05492.1 - 0.23 11.3 0.2 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Exonuc_VII_S PF02609.16 EGB05492.1 - 0.42 10.7 2.7 12 6.1 0.3 3.4 2 0 0 2 2 2 0 Exonuclease VII small subunit WD40 PF00400.32 EGB05492.1 - 0.43 11.5 8.4 0.58 11.1 0.0 5.3 8 0 0 8 8 7 0 WD domain, G-beta repeat MIT PF04212.18 EGB05492.1 - 0.6 10.2 15.2 4.3 7.5 0.2 5.5 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EGB05492.1 - 1.7 8.8 29.8 1.2 9.3 0.0 8.7 9 1 0 9 9 8 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGB05493.1 - 2.9e-09 37.4 0.2 4.5e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB05493.1 - 5e-08 33.3 0.2 1.2e-07 32.1 0.2 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB05493.1 - 4.9e-07 29.9 1.0 0.02 15.4 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGB05493.1 - 6.8e-06 26.3 1.1 0.00038 20.7 0.6 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB05493.1 - 3.9e-05 23.7 0.6 0.24 12.1 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat RtcB PF01139.17 EGB05497.1 - 3.2e-146 487.7 0.0 3.7e-146 487.5 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Ubiq-assoc PF09145.10 EGB05497.1 - 0.18 11.8 1.2 0.46 10.5 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin-associated HSF_DNA-bind PF00447.17 EGB05498.1 - 2.9e-26 91.9 0.0 3.3e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding GHMP_kinases_C PF08544.13 EGB05499.1 - 3.4e-11 43.3 3.8 7.8e-11 42.2 3.8 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGB05499.1 - 1.9e-08 34.4 2.8 1.9e-08 34.4 2.8 3.1 3 1 0 3 3 3 1 GHMP kinases N terminal domain Lectin_C_term PF18022.1 EGB05500.1 - 0.0009 19.7 0.4 14 6.2 0.0 3.2 3 0 0 3 3 3 3 Ricin-type beta-trefoil lectin C-terminal domain Ribosomal_L19e PF01280.20 EGB05500.1 - 0.061 13.4 1.2 57 3.8 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein L19e Cas1_AcylT PF07779.12 EGB05501.1 - 1.9e-90 304.1 8.1 2.3e-90 303.8 8.1 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p HA PF03457.14 EGB05503.1 - 1.2e-14 54.4 0.0 0.00016 21.9 0.0 4.7 4 1 0 4 4 4 3 Helicase associated domain LYRIC PF15686.5 EGB05503.1 - 0.00023 20.9 7.6 0.00041 20.1 7.6 1.3 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Trypan_PARP PF05887.11 EGB05503.1 - 5.7 6.9 35.0 1.2 9.1 18.9 3.2 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Sulfotransfer_3 PF13469.6 EGB05504.1 - 1e-36 127.4 0.0 2.8e-36 125.9 0.0 1.8 2 1 0 2 2 2 1 Sulfotransferase family Glyco_hydro_18 PF00704.28 EGB05504.1 - 6.5e-16 58.9 7.0 1.1e-14 54.9 7.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Sulfotransfer_1 PF00685.27 EGB05504.1 - 8e-05 22.2 0.0 0.00032 20.2 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 EGB05504.1 - 0.032 14.1 0.0 0.19 11.5 0.0 2.0 1 1 0 1 1 1 0 Sulfotransferase domain Fve PF09259.11 EGB05504.1 - 0.14 12.3 0.2 0.39 10.9 0.2 1.7 1 0 0 1 1 1 0 Fungal immunomodulatory protein Fve Mito_carr PF00153.27 EGB05505.1 - 2.3e-29 101.1 1.5 5e-10 39.2 0.0 4.1 2 1 2 4 4 4 3 Mitochondrial carrier protein Abhydrolase_1 PF00561.20 EGB05505.1 - 0.022 14.4 0.4 0.036 13.7 0.4 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PQ-loop PF04193.14 EGB05507.1 - 1.5e-16 59.9 1.0 8.1e-09 35.1 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat PX PF00787.24 EGB05509.1 - 1.4e-13 50.8 0.0 1.5e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 PX domain DNA_meth_N PF18284.1 EGB05509.1 - 0.0089 15.9 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 DNA methylase N-terminal domain UQ_con PF00179.26 EGB05511.1 - 6.3e-23 81.0 0.0 7e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGB05511.1 - 0.011 15.6 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 0 UEV domain GCS PF03074.16 EGB05512.1 - 1.9e-149 498.0 0.0 2.4e-149 497.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 EGB05512.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) EF-hand_8 PF13833.6 EGB05513.1 - 1.5e-07 31.2 0.1 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB05513.1 - 2.7e-07 30.0 0.8 0.028 14.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB05513.1 - 2.9e-06 26.4 2.5 0.049 13.2 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB05513.1 - 1.2e-05 25.7 0.2 0.1 13.0 0.0 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB05513.1 - 0.00025 20.4 0.5 0.51 9.9 0.1 2.7 2 0 0 2 2 2 2 EF hand Ribosomal_S21 PF01165.20 EGB05514.1 - 8.7e-13 47.8 9.1 8.7e-13 47.8 9.1 2.3 2 0 0 2 2 2 1 Ribosomal protein S21 GST_C PF00043.25 EGB05514.1 - 9.5e-10 38.6 0.1 3.6e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB05514.1 - 9.9e-06 25.8 0.0 3e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB05514.1 - 6.9e-05 23.2 0.0 0.00021 21.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB05514.1 - 0.0014 18.8 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EGB05514.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EGB05514.1 - 0.016 16.0 0.0 0.032 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 EGB05514.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PVL_ORF50 PF07768.11 EGB05514.1 - 1.2 9.5 8.1 1.9 8.9 8.1 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family 2-oxoacid_dh PF00198.23 EGB05515.1 - 4.8e-41 140.7 0.0 9.1e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGB05515.1 - 3.3e-17 62.1 1.9 5.8e-17 61.3 1.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGB05515.1 - 4.1e-12 46.2 2.1 8.8e-12 45.2 2.1 1.6 1 0 0 1 1 1 1 e3 binding domain Ephrin_rec_like PF07699.13 EGB05515.1 - 8.6e-11 41.4 354.3 2.3e-05 24.1 3.7 36.4 21 9 14 37 37 37 18 Putative ephrin-receptor like Biotin_lipoyl_2 PF13533.6 EGB05515.1 - 0.12 12.3 0.1 0.36 10.7 0.0 1.8 1 1 1 2 2 2 0 Biotin-lipoyl like DUF3336 PF11815.8 EGB05516.1 - 6.1e-24 84.3 0.0 9.8e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGB05516.1 - 6.6e-19 68.9 0.0 1.7e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase RNase_PH PF01138.21 EGB05517.1 - 1.2e-29 103.5 0.0 8e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 S1 PF00575.23 EGB05517.1 - 1.5e-15 57.3 0.1 3.3e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 EGB05517.1 - 1.5e-09 37.5 0.1 3.2e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 EGB05517.1 - 0.0088 16.1 0.1 0.023 14.7 0.1 1.7 1 0 0 1 1 1 1 NusA-like KH domain KH_4 PF13083.6 EGB05517.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 KH domain ArsA_ATPase PF02374.15 EGB05518.1 - 6.2e-57 193.1 0.0 8.5e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 EGB05518.1 - 2.1e-07 31.0 0.0 3.3e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGB05518.1 - 4.6e-07 29.9 0.0 2.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EGB05518.1 - 0.002 17.6 0.0 0.007 15.8 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein SRP54 PF00448.22 EGB05518.1 - 0.0035 17.0 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain ParA PF10609.9 EGB05518.1 - 0.0048 16.4 0.4 0.0048 16.4 0.4 1.9 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EGB05518.1 - 0.0097 15.4 0.2 0.018 14.5 0.2 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_24 PF13479.6 EGB05518.1 - 0.046 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3197 PF11432.8 EGB05518.1 - 0.11 12.5 0.2 0.54 10.2 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3197) SNF2_N PF00176.23 EGB05519.1 - 1.6e-51 175.1 0.0 2.5e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB05519.1 - 3.5e-17 62.7 0.0 2.5e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 EGB05519.1 - 1.9e-08 34.1 1.8 3e-08 33.4 1.8 1.3 1 0 0 1 1 1 1 PHD-finger ResIII PF04851.15 EGB05519.1 - 4.2e-08 33.4 0.0 7.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_2 PF13831.6 EGB05519.1 - 0.00034 20.1 0.5 0.00064 19.2 0.5 1.4 1 0 0 1 1 1 1 PHD-finger SWI2_SNF2 PF18766.1 EGB05519.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Prok-RING_1 PF14446.6 EGB05519.1 - 0.083 12.8 1.5 0.22 11.5 1.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 EGB05519.1 - 0.22 11.9 1.4 0.4 11.1 1.4 1.5 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 EGB05519.1 - 0.26 11.2 3.1 0.14 12.1 0.4 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EGB05519.1 - 0.36 10.4 1.3 0.58 9.8 1.3 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 EGB05519.1 - 7.3 6.8 8.1 1.8e+02 2.3 8.1 2.3 1 1 0 1 1 1 0 KIAA1045 RING finger Pkinase PF00069.25 EGB05520.1 - 5.6e-46 157.0 0.0 7.7e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05520.1 - 2.2e-17 63.2 0.0 3.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB05520.1 - 1.9e-06 27.4 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB05520.1 - 5e-05 23.3 0.4 0.00022 21.2 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB05520.1 - 0.018 13.8 0.0 0.033 13.0 0.0 1.3 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 EGB05520.1 - 0.2 10.9 0.0 0.96 8.7 0.0 1.8 1 1 0 1 1 1 0 Kinase-like LepA_C PF06421.12 EGB05521.1 - 1e-34 118.9 0.7 1.5e-34 118.4 0.7 1.2 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EGB05521.1 - 1.1e-11 44.6 0.0 2.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGB05521.1 - 3e-08 33.9 0.7 8.3e-08 32.5 0.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 EGB05521.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 EGB05521.1 - 0.00083 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 EGB05521.1 - 0.026 14.6 0.0 0.13 12.4 0.0 2.0 1 1 0 1 1 1 0 Elongation Factor G, domain II DUF1918 PF08940.11 EGB05521.1 - 0.34 10.6 2.1 5.6 6.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) TRAM_LAG1_CLN8 PF03798.16 EGB05522.1 - 1e-08 35.2 0.1 1.2e-08 35.0 0.1 1.0 1 0 0 1 1 1 1 TLC domain PWI PF01480.17 EGB05523.1 - 1.5e-27 95.7 0.2 2.3e-27 95.1 0.2 1.3 1 0 0 1 1 1 1 PWI domain Rotamase PF00639.21 EGB05524.1 - 3e-17 63.4 0.0 3.8e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGB05524.1 - 2e-10 41.2 0.0 3.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EGB05524.1 - 1.4e-07 32.3 0.4 1.8e-07 32.0 0.4 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EGB05524.1 - 0.0013 18.8 0.9 0.002 18.2 0.9 1.4 1 0 0 1 1 1 1 WW domain SIMPL PF04402.14 EGB05524.1 - 0.12 12.8 4.0 0.12 12.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Sigma70_r2 PF04542.14 EGB05525.1 - 1.6e-16 59.9 3.5 5.5e-16 58.1 2.7 2.3 2 1 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 EGB05525.1 - 2.7e-10 40.2 0.1 1.6e-07 31.3 0.0 2.8 2 1 0 2 2 2 2 Sigma-70 region 3 Sigma70_r4 PF04545.16 EGB05525.1 - 7.6e-08 31.8 1.1 7.6e-08 31.8 1.1 3.2 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 EGB05525.1 - 0.033 14.2 1.4 0.067 13.2 0.0 2.2 3 0 0 3 3 3 0 Sigma-70 factor, region 1.2 Ribosomal_S9 PF00380.19 EGB05526.1 - 1.9e-32 112.4 0.1 2.1e-32 112.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 IMS PF00817.20 EGB05527.1 - 1.1e-25 90.4 0.0 1.7e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family Ribosomal_L36e PF01158.18 EGB05528.1 - 2.5e-28 98.1 7.9 2.8e-28 98.0 7.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Dermcidin PF15291.6 EGB05528.1 - 0.035 14.6 0.1 0.048 14.2 0.1 1.2 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide zf-MYND PF01753.18 EGB05529.1 - 8.4e-09 35.4 15.6 1.6e-08 34.5 15.6 1.5 1 0 0 1 1 1 1 MYND finger FSH1 PF03959.13 EGB05529.1 - 0.00032 20.4 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) zf-HIT PF04438.16 EGB05529.1 - 0.26 11.2 14.9 0.025 14.5 10.4 1.7 2 0 0 2 2 2 0 HIT zinc finger zf-C6H2 PF15801.5 EGB05529.1 - 1 9.7 8.1 2.1 8.7 8.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RSN1_7TM PF02714.15 EGB05530.1 - 6e-26 91.4 18.7 9.6e-26 90.7 18.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGB05530.1 - 3e-18 66.1 0.3 3e-18 66.1 0.3 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGB05530.1 - 4e-11 43.4 0.0 6.1e-05 23.3 0.0 2.9 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EGB05530.1 - 0.015 14.1 0.1 0.015 14.1 0.1 2.6 3 0 0 3 3 3 0 Calcium-activated chloride channel TIP49 PF06068.13 EGB05531.1 - 5.5e-152 506.0 6.2 1.6e-100 336.7 1.0 2.8 2 1 1 3 3 3 2 TIP49 P-loop domain TIP49_C PF17856.1 EGB05531.1 - 1.1e-23 83.1 1.8 2.7e-23 81.8 1.8 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGB05531.1 - 2.5e-09 37.7 0.4 1.6e-06 28.6 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EGB05531.1 - 4.3e-07 29.5 0.3 9.2e-07 28.4 0.3 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EGB05531.1 - 1e-06 29.0 0.3 0.0064 16.8 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 EGB05531.1 - 2.4e-06 27.6 0.1 0.0014 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGB05531.1 - 4.9e-06 26.4 0.8 0.0029 17.4 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EGB05531.1 - 0.00028 20.3 0.4 0.0075 15.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGB05531.1 - 0.00042 19.9 0.2 0.0012 18.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB05531.1 - 0.00095 19.6 4.2 0.0019 18.6 1.6 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EGB05531.1 - 0.0013 18.7 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 EGB05531.1 - 0.0015 18.8 2.5 0.028 14.7 2.5 2.5 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGB05531.1 - 0.0034 17.1 0.1 1.8 8.3 0.1 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 EGB05531.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EGB05531.1 - 0.014 14.9 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 EGB05531.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF688 PF05097.12 EGB05531.1 - 0.021 14.0 1.1 0.031 13.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) TsaE PF02367.17 EGB05531.1 - 0.022 14.7 0.8 0.058 13.4 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGB05531.1 - 0.028 14.7 0.2 0.1 12.9 0.2 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGB05531.1 - 0.03 13.6 0.4 0.075 12.2 0.4 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 EGB05531.1 - 0.044 14.3 0.2 0.34 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGB05531.1 - 0.053 12.8 0.9 0.11 11.8 0.2 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EGB05531.1 - 0.078 12.7 4.6 1.7 8.3 2.6 2.5 2 1 0 2 2 2 0 AAA domain PDT PF00800.18 EGB05531.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Prephenate dehydratase Parvo_NS1 PF01057.17 EGB05531.1 - 0.19 10.8 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cwf_Cwc_15 PF04889.12 EGB05531.1 - 0.4 10.4 5.5 0.78 9.4 5.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CBFD_NFYB_HMF PF00808.23 EGB05532.1 - 6.9e-19 67.9 2.0 3.1e-18 65.8 2.0 1.8 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB05532.1 - 3.6e-16 59.7 0.2 3.8e-16 59.6 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGB05532.1 - 0.00039 20.5 0.3 0.001 19.2 0.1 1.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-X PF09415.10 EGB05532.1 - 0.0054 17.0 0.0 0.006 16.9 0.0 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X GFO_IDH_MocA PF01408.22 EGB05533.1 - 2.4e-08 34.8 0.0 5.5e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 EGB05533.1 - 0.029 14.8 0.0 0.082 13.4 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain E1-E2_ATPase PF00122.20 EGB05534.1 - 3.4e-44 150.5 0.8 8.5e-44 149.2 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGB05534.1 - 4.7e-42 143.8 0.2 4.7e-42 143.8 0.2 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGB05534.1 - 1.4e-19 69.9 0.0 2.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGB05534.1 - 2.5e-19 70.4 7.9 2.7e-18 67.0 5.8 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGB05534.1 - 1.1e-13 50.7 0.0 2.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGB05534.1 - 0.00013 21.8 0.8 0.0024 17.6 1.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB05534.1 - 0.00028 21.3 1.3 0.0038 17.6 0.7 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase La PF05383.17 EGB05535.1 - 1.6e-18 66.5 0.0 3.9e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 EGB05535.1 - 2.5e-12 46.7 3.6 3.3e-12 46.3 0.1 2.5 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 EGB05535.1 - 0.00016 21.4 0.0 0.002 17.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 EGB05536.1 - 5.2e-74 249.3 0.8 7.5e-74 248.8 0.8 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Sulfotransfer_2 PF03567.14 EGB05536.1 - 0.3 11.0 0.0 0.95 9.3 0.0 1.7 2 1 0 2 2 2 0 Sulfotransferase family Acyltransferase PF01553.21 EGB05537.1 - 7e-14 51.6 0.0 9.7e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase RcsC PF09456.10 EGB05537.1 - 0.095 12.7 0.0 0.38 10.8 0.0 1.8 1 1 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) TPT PF03151.16 EGB05538.1 - 8.8e-81 271.4 10.9 2.3e-71 240.5 6.9 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EGB05538.1 - 5.7e-14 52.4 16.7 2.8e-07 30.8 3.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGB05538.1 - 0.23 10.6 5.4 0.47 9.6 5.4 1.5 1 1 0 1 1 1 0 UAA transporter family zf-RanBP PF00641.18 EGB05539.1 - 3.7e-13 48.5 42.4 3.8e-05 22.9 3.1 4.3 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others DZR PF12773.7 EGB05539.1 - 4.5e-06 26.6 23.5 0.00034 20.6 9.3 3.3 2 1 1 3 3 3 3 Double zinc ribbon FAST_1 PF06743.15 EGB05539.1 - 0.0085 16.0 0.0 1.3 9.0 0.0 3.1 1 1 2 3 3 3 2 FAST kinase-like protein, subdomain 1 PHD_4 PF16866.5 EGB05539.1 - 1.5 8.9 18.0 12 6.1 1.4 4.4 4 0 0 4 4 4 0 PHD-finger Rubredoxin PF00301.20 EGB05539.1 - 2.4 8.3 21.8 5.7 7.0 0.9 5.2 6 0 0 6 6 6 0 Rubredoxin zf-P11 PF03854.14 EGB05539.1 - 3.3 7.4 24.5 0.49 10.1 2.0 4.1 4 0 0 4 4 4 0 P-11 zinc finger Mito_fiss_reg PF05308.11 EGB05539.1 - 7.2 6.6 13.7 4.3 7.4 2.5 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator GTP_EFTU PF00009.27 EGB05540.1 - 4.8e-31 107.8 2.9 2.6e-29 102.1 2.9 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGB05540.1 - 3.2e-21 75.4 0.5 3.2e-21 75.4 0.5 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGB05540.1 - 1.3e-09 38.1 0.2 3.3e-09 36.8 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EGB05540.1 - 1.1e-08 34.7 0.4 3.6e-08 33.1 0.4 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 EGB05540.1 - 3.6e-06 26.5 0.0 7.2e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGB05540.1 - 0.0001 22.2 1.1 0.012 15.5 0.2 2.6 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EGB05540.1 - 0.00029 20.4 0.3 0.00089 18.8 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EGB05540.1 - 0.00049 19.6 0.0 0.002 17.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGB05540.1 - 0.0014 18.4 0.0 0.006 16.3 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EGB05540.1 - 0.0052 17.0 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGB05540.1 - 0.012 15.7 0.0 2.5 8.1 0.0 2.3 1 1 1 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 EGB05540.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Glyco_hydro_2_C PF02836.17 EGB05541.1 - 2.4e-47 161.5 0.0 2.9e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EGB05541.1 - 0.00011 22.8 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 TFIIA PF03153.13 EGB05542.1 - 0.026 14.5 16.2 0.046 13.7 16.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit URO-D PF01208.17 EGB05543.1 - 1.2e-99 333.8 0.0 1.5e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) cNMP_binding PF00027.29 EGB05544.1 - 4.4e-21 74.7 0.0 6.4e-06 26.2 0.0 4.1 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EGB05544.1 - 1.4e-06 28.6 6.2 1.4e-06 28.6 6.2 2.9 2 0 0 2 2 2 1 Patatin-like phospholipase EF-hand_1 PF00036.32 EGB05544.1 - 4.7e-06 25.8 0.1 0.004 16.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB05544.1 - 0.00012 22.4 0.4 0.00025 21.4 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB05544.1 - 0.00032 20.4 0.4 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB05544.1 - 0.00033 20.0 2.0 0.12 11.9 0.1 2.5 2 0 0 2 2 2 2 EF hand LETM1 PF07766.13 EGB05544.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein EF-hand_8 PF13833.6 EGB05544.1 - 0.0062 16.4 0.2 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair UPF0242 PF06785.11 EGB05545.1 - 0.013 15.6 0.3 0.042 14.0 0.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 EGB05545.1 - 0.027 14.7 11.3 0.31 11.3 0.7 4.2 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.6 EGB05545.1 - 0.053 12.2 6.3 0.086 11.5 6.3 1.2 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 EGB05545.1 - 0.065 13.7 17.8 1.2 9.6 9.7 2.2 2 0 0 2 2 2 0 Fez1 TRAF_BIRC3_bd PF16673.5 EGB05545.1 - 0.11 12.3 0.4 0.11 12.3 0.4 4.2 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Prefoldin_2 PF01920.20 EGB05545.1 - 0.36 10.8 4.5 0.48 10.4 0.1 3.1 4 0 0 4 4 4 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 EGB05545.1 - 2 8.4 21.1 0.075 13.0 3.3 3.9 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 EGB05545.1 - 7.1 5.6 6.0 14 4.7 6.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PAF-AH_p_II PF03403.13 EGB05546.1 - 2.6e-13 49.3 0.0 6.1e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 EGB05546.1 - 2.2e-09 37.0 0.7 1.7e-07 30.7 0.4 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGB05546.1 - 1.2e-05 24.9 0.6 0.00032 20.2 0.7 2.7 3 1 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGB05546.1 - 0.00023 20.9 0.8 0.043 13.4 0.1 2.9 2 1 1 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.18 EGB05546.1 - 0.00092 18.8 0.2 0.0021 17.7 0.2 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EGB05546.1 - 0.0024 16.8 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S15 PF02129.18 EGB05546.1 - 0.0027 17.3 0.6 0.0053 16.4 0.6 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 EGB05546.1 - 0.026 14.3 0.0 4.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EGB05546.1 - 0.042 12.9 0.0 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase CRAL_TRIO PF00650.20 EGB05547.1 - 1.6e-21 76.7 0.0 2.2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Sel1 PF08238.12 EGB05548.1 - 4.4e-30 103.4 32.0 1.1e-08 35.4 0.3 5.8 5 1 0 5 5 5 5 Sel1 repeat TPR_11 PF13414.6 EGB05548.1 - 1.3 8.8 12.9 0.92 9.2 0.2 4.4 3 2 1 4 4 4 0 TPR repeat TPR_7 PF13176.6 EGB05548.1 - 2.6 8.3 9.9 8.5 6.7 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Methyltransf_12 PF08242.12 EGB05549.1 - 4.6e-09 36.9 0.0 1.5e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB05549.1 - 2.9e-08 34.3 0.1 2.4e-07 31.3 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB05549.1 - 1.7e-07 31.2 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB05549.1 - 1.5e-06 28.7 0.2 1.4e-05 25.6 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05549.1 - 0.0037 17.1 0.0 0.024 14.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB05549.1 - 0.0087 15.6 0.1 0.039 13.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Ribonuc_red_lgC PF02867.15 EGB05550.1 - 1.2e-182 608.2 0.0 1.7e-182 607.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGB05550.1 - 1.3e-23 82.8 0.1 3.5e-23 81.4 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGB05550.1 - 7.2e-18 64.9 0.1 2e-17 63.6 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain Amidase PF01425.21 EGB05551.1 - 1.9e-56 191.9 2.4 2.4e-56 191.6 2.4 1.1 1 0 0 1 1 1 1 Amidase DUF4332 PF14229.6 EGB05551.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) HEAT PF02985.22 EGB05551.1 - 0.17 12.2 4.2 0.34 11.3 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat Caudal_act PF04731.12 EGB05551.1 - 0.18 12.2 2.4 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 Caudal like protein activation region adh_short PF00106.25 EGB05552.1 - 2e-21 76.3 0.1 2.8e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGB05552.1 - 1.3e-17 64.1 0.6 4.2e-08 33.0 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Helicase_C PF00271.31 EGB05553.1 - 0.0082 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_pol_phi PF04931.13 EGB05556.1 - 0.0096 14.1 3.2 0.011 13.9 3.2 1.0 1 0 0 1 1 1 1 DNA polymerase phi Cwf_Cwc_15 PF04889.12 EGB05556.1 - 0.01 15.6 5.2 0.016 15.0 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 EGB05556.1 - 0.017 15.8 8.8 0.027 15.1 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.8 EGB05556.1 - 0.026 14.8 5.0 0.038 14.2 5.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ThiC_Rad_SAM PF01964.18 EGB05556.1 - 0.076 11.8 0.4 0.34 9.6 0.0 2.0 2 1 0 2 2 2 0 Radical SAM ThiC family GOLD_2 PF13897.6 EGB05556.1 - 0.12 12.8 1.0 0.2 12.2 1.0 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking WRNPLPNID PF15017.6 EGB05556.1 - 0.34 11.8 2.8 19 6.2 0.0 2.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Ribosomal_60s PF00428.19 EGB05556.1 - 1.2 9.7 8.7 0.18 12.4 4.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein PK PF00224.21 EGB05557.1 - 1.5e-109 366.1 0.0 2.2e-109 365.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGB05557.1 - 2.8e-08 34.0 6.2 7.2e-08 32.7 2.7 2.7 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain Prot_ATP_OB_N PF17758.1 EGB05557.1 - 0.028 14.1 0.9 0.092 12.4 0.1 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Chloroa_b-bind PF00504.21 EGB05558.1 - 3.6e-29 102.4 0.0 4.7e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Peptidase_C12 PF01088.21 EGB05560.1 - 1.6e-64 217.5 0.0 3.7e-64 216.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGB05560.1 - 2.8e-18 65.5 0.3 6.6e-18 64.3 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Ank_4 PF13637.6 EGB05561.1 - 2.2e-09 37.7 2.4 1.4e-05 25.6 0.2 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB05561.1 - 2.1e-07 31.5 0.2 6.6e-05 23.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB05561.1 - 0.0019 18.5 0.3 0.42 11.3 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EGB05561.1 - 0.083 13.2 0.1 0.5 10.8 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 EGB05561.1 - 0.1 13.1 2.6 18 6.0 0.1 4.0 4 0 0 4 4 4 0 Ankyrin repeat Omp_AT PF11557.8 EGB05561.1 - 0.23 10.4 0.4 0.43 9.5 0.4 1.3 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain DnaJ PF00226.31 EGB05563.1 - 9.6e-22 76.9 0.0 1.1e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 EGB05564.1 - 2.1e-65 220.7 0.0 2.3e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05564.1 - 2.7e-45 154.7 0.0 3.3e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB05564.1 - 1.3e-05 24.1 0.0 1.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB05564.1 - 2.1e-05 24.0 0.0 0.00051 19.4 0.0 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGB05564.1 - 0.00098 19.1 0.2 0.54 10.1 0.1 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB05564.1 - 0.056 12.8 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB05564.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Methyltransf_11 PF08241.12 EGB05565.1 - 7e-23 81.1 0.0 1.2e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB05565.1 - 9e-22 77.6 0.0 1.9e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05565.1 - 8.4e-18 64.6 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB05565.1 - 1.1e-16 61.2 0.0 1.5e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB05565.1 - 1.7e-14 54.3 0.0 3.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB05565.1 - 1.6e-12 47.3 0.0 2.1e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGB05565.1 - 3.4e-10 39.6 0.1 5.1e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EGB05565.1 - 6.6e-08 31.5 0.0 8.6e-08 31.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 EGB05565.1 - 6.2e-06 25.8 0.0 0.002 17.6 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.14 EGB05565.1 - 0.00036 20.1 0.0 0.00088 18.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EGB05565.1 - 0.00046 20.1 0.0 0.00095 19.1 0.0 1.5 2 0 0 2 2 2 1 Hypothetical methyltransferase DREV PF05219.12 EGB05565.1 - 0.003 16.7 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 EGB05565.1 - 0.0054 16.5 0.0 0.0068 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NAS PF03059.16 EGB05565.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein TehB PF03848.14 EGB05565.1 - 0.037 13.4 0.0 0.074 12.5 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.19 EGB05565.1 - 0.056 13.5 0.0 0.34 11.0 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase ADH_zinc_N PF00107.26 EGB05565.1 - 0.12 12.4 0.1 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase p450 PF00067.22 EGB05566.1 - 2e-51 175.2 0.0 2.4e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF547 PF04784.14 EGB05568.1 - 2.3e-15 56.7 0.0 4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF547 EF-hand_1 PF00036.32 EGB05569.1 - 1.4e-16 58.7 1.6 3.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB05569.1 - 1.5e-14 54.1 0.2 1.7e-14 54.0 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB05569.1 - 1.9e-12 46.8 0.2 1.2e-08 34.7 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB05569.1 - 2.1e-12 45.9 0.2 3.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB05569.1 - 1.3e-11 43.4 1.4 4e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EGB05569.1 - 4.9e-06 26.4 0.1 6.2e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 EGB05569.1 - 0.0028 16.3 0.0 0.0029 16.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 EGB05569.1 - 0.0073 16.6 0.0 0.0084 16.4 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Sep15_SelM PF08806.11 EGB05571.1 - 7.1e-19 67.8 0.1 2.4e-18 66.0 0.0 1.9 3 0 0 3 3 3 1 Sep15/SelM redox domain BTB_2 PF02214.22 EGB05572.1 - 4.3e-11 43.0 0.0 8.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Arylsulfotran_2 PF14269.6 EGB05572.1 - 2.7e-05 23.7 1.4 4.1e-05 23.1 1.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) MTS PF05175.14 EGB05572.1 - 0.0093 15.5 0.3 0.032 13.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Arylsulfotrans PF05935.11 EGB05572.1 - 0.025 13.5 0.2 0.058 12.3 0.1 1.5 1 1 0 1 1 1 0 Arylsulfotransferase (ASST) PrmA PF06325.13 EGB05572.1 - 0.037 13.4 1.0 0.053 12.9 0.2 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGB05572.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Afaf PF15339.6 EGB05572.1 - 0.23 11.1 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor GATA PF00320.27 EGB05573.1 - 3.9e-05 23.2 41.2 0.049 13.2 2.2 8.2 7 1 0 7 7 7 3 GATA zinc finger WSD PF15613.6 EGB05573.1 - 0.055 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF4428 PF14471.6 EGB05573.1 - 0.27 11.2 2.9 23 5.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-C2H2 PF00096.26 EGB05573.1 - 0.29 11.7 21.7 6.2 7.5 0.5 6.5 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EGB05573.1 - 3 8.5 6.6 7.4 7.3 0.0 3.7 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 EGB05573.1 - 6.6 6.8 21.2 3.1 7.9 0.1 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger p450 PF00067.22 EGB05574.1 - 9.5e-50 169.7 0.0 1.3e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BRF1 PF07741.13 EGB05574.1 - 0.19 12.1 1.6 0.22 11.9 0.1 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Fib_alpha PF08702.10 EGB05575.1 - 0.015 15.5 5.4 0.023 14.9 5.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DNA_meth_N PF18284.1 EGB05575.1 - 0.028 14.3 0.2 0.12 12.3 0.4 1.9 2 0 0 2 2 2 0 DNA methylase N-terminal domain DUF1664 PF07889.12 EGB05575.1 - 0.1 12.6 2.9 0.54 10.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2721 PF11026.8 EGB05575.1 - 0.65 9.9 3.8 0.16 11.9 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) HAUS5 PF14817.6 EGB05575.1 - 0.77 8.4 12.1 1.1 7.9 12.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Tropomyosin_1 PF12718.7 EGB05575.1 - 1.3 9.1 17.5 0.46 10.6 7.9 2.3 1 1 1 2 2 2 0 Tropomyosin like LMBR1 PF04791.16 EGB05575.1 - 1.6 7.6 3.1 1.8 7.4 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein VSG_B PF13206.6 EGB05575.1 - 1.6 7.9 8.6 2.2 7.4 8.6 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain SlyX PF04102.12 EGB05575.1 - 1.9 9.2 7.3 3.9 8.2 2.2 2.7 2 0 0 2 2 2 0 SlyX Siah-Interact_N PF09032.11 EGB05575.1 - 5.5 7.4 7.9 3.1 8.2 1.4 2.5 2 0 0 2 2 2 0 Siah interacting protein, N terminal Exonuc_VII_L PF02601.15 EGB05575.1 - 6.2 6.3 7.8 8.7 5.8 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Kelch_3 PF13415.6 EGB05576.1 - 1.4e-21 76.2 0.5 3.9e-05 23.8 0.0 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGB05576.1 - 1.7e-19 69.6 1.2 8.8e-05 22.4 0.2 5.0 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB05576.1 - 7.2e-17 61.0 6.7 0.0014 18.6 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGB05576.1 - 2.1e-10 40.5 0.0 0.063 13.6 0.0 5.0 5 2 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EGB05576.1 - 2.3e-10 39.9 0.2 5.3e-05 22.7 0.0 4.3 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EGB05576.1 - 1.3e-09 37.7 0.1 0.14 12.2 0.0 4.5 4 0 0 4 4 4 3 Kelch motif DNA_pol_B PF00136.21 EGB05577.1 - 3.3e-114 382.1 0.0 5.6e-113 378.1 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EGB05577.1 - 6.7e-34 117.3 3.7 1.2e-33 116.4 3.7 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EGB05577.1 - 5.5e-29 101.4 0.0 9.2e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 EGB05577.1 - 0.01 14.8 0.1 0.021 13.7 0.0 1.4 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 EGB05577.1 - 0.031 12.9 0.1 0.049 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) MazG-like PF12643.7 EGB05578.1 - 2.7e-14 53.2 0.0 3.7e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 EGB05578.1 - 2.4e-05 24.4 0.0 4.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain UCH PF00443.29 EGB05579.1 - 1.8e-69 234.1 0.0 2.1e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB05579.1 - 6.4e-17 62.1 0.0 6.2e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EGB05579.1 - 0.21 11.2 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DHHC PF01529.20 EGB05580.1 - 4.7e-14 52.6 2.7 4.7e-14 52.6 2.7 2.1 3 0 0 3 3 3 1 DHHC palmitoyltransferase Rieske_2 PF13806.6 EGB05581.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain MIF PF01187.18 EGB05582.1 - 3.2e-21 75.8 0.0 3.5e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Ion_trans PF00520.31 EGB05583.1 - 2.7e-13 49.7 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB05583.1 - 3.2e-13 49.4 0.5 3.2e-13 49.4 0.5 1.8 2 0 0 2 2 2 1 Ion channel LRR_6 PF13516.6 EGB05584.1 - 4.8e-11 41.8 5.3 8.2e-08 31.7 0.1 3.4 3 0 0 3 3 3 3 Leucine Rich repeat LRR_8 PF13855.6 EGB05584.1 - 0.01 15.6 0.2 0.4 10.5 0.0 2.8 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 EGB05584.1 - 0.02 15.3 1.4 0.27 11.7 0.4 2.7 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB05584.1 - 0.079 13.5 0.4 6.6 7.7 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat Peptidase_M17 PF00883.21 EGB05585.1 - 1.5e-91 306.9 0.9 2.1e-91 306.5 0.9 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 EGB05585.1 - 4.5e-17 62.4 2.2 3.2e-16 59.7 1.4 2.4 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 Nucleotid_trans PF03407.16 EGB05586.1 - 1.2e-09 38.5 0.0 2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase 6PF2K PF01591.18 EGB05587.1 - 0.026 13.8 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Cupin_4 PF08007.12 EGB05588.1 - 1.2e-27 97.3 0.2 3.5e-27 95.7 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 EGB05588.1 - 3.1e-06 27.1 0.2 0.0014 18.4 0.0 2.6 2 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 EGB05588.1 - 0.04 13.6 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 EGB05588.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Cupin Bromodomain PF00439.25 EGB05589.1 - 2.6e-18 65.8 0.0 1.4e-07 31.5 0.0 4.0 3 1 0 3 3 3 3 Bromodomain EF-hand_8 PF13833.6 EGB05590.1 - 0.13 12.2 1.1 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair DUF908 PF06012.12 EGB05590.1 - 0.36 10.2 4.2 0.6 9.5 4.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Plasmodium_Vir PF05795.11 EGB05590.1 - 6.8 6.0 5.3 12 5.2 5.3 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 EGB05590.1 - 7.4 5.2 8.7 11 4.7 8.7 1.2 1 0 0 1 1 1 0 Presenilin Pyr_redox_2 PF07992.14 EGB05592.1 - 6.8e-30 104.3 0.6 1e-29 103.8 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DoxX PF07681.12 EGB05592.1 - 4.9e-13 49.5 26.5 2.2e-07 31.4 1.9 4.3 4 0 0 4 4 4 2 DoxX 2OG-FeII_Oxy PF03171.20 EGB05592.1 - 8.5e-10 39.0 0.0 0.0039 17.6 0.0 3.1 4 0 0 4 4 4 2 2OG-Fe(II) oxygenase superfamily Pyr_redox PF00070.27 EGB05592.1 - 1.8e-08 34.8 1.1 3.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DoxX_2 PF13564.6 EGB05592.1 - 3.8e-06 26.9 3.7 0.058 13.5 0.3 3.8 2 0 0 2 2 2 2 DoxX-like family Form-deh_trans PF09163.11 EGB05592.1 - 0.0012 18.6 2.4 2.1 8.2 0.2 3.5 2 0 0 2 2 2 2 Formate dehydrogenase N, transmembrane Fer4_19 PF06902.11 EGB05592.1 - 0.17 12.0 0.0 48 4.1 0.0 2.9 3 0 0 3 3 3 0 Divergent 4Fe-4S mono-cluster NAD_binding_9 PF13454.6 EGB05592.1 - 0.19 11.7 3.0 11 6.0 0.0 3.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Collagen_mid PF15984.5 EGB05592.1 - 1.1 8.9 5.4 4.5 7.0 0.4 2.3 2 0 0 2 2 2 0 Bacterial collagen, middle region ADH_zinc_N_2 PF13602.6 EGB05593.1 - 1e-09 39.6 0.0 1.9e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGB05593.1 - 4.8e-09 36.3 0.0 7.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB05593.1 - 0.029 14.3 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain DnaJ PF00226.31 EGB05594.1 - 1.7e-27 95.3 3.9 2.1e-27 95.0 3.9 1.1 1 0 0 1 1 1 1 DnaJ domain GRP PF07172.11 EGB05594.1 - 0.011 16.4 2.5 0.016 15.9 2.5 1.2 1 0 0 1 1 1 0 Glycine rich protein family SH3_9 PF14604.6 EGB05595.1 - 1.5e-14 53.6 0.1 1.6e-14 53.5 0.1 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGB05595.1 - 1.7e-13 50.0 0.0 1.8e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB05595.1 - 1.8e-13 49.8 0.1 2e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 SH3 domain SH3_10 PF17902.1 EGB05595.1 - 0.0065 16.5 0.0 0.0066 16.5 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGB05596.1 - 5.3e-16 58.2 0.1 5.8e-16 58.1 0.1 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB05596.1 - 3.4e-13 49.0 0.1 3.7e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGB05596.1 - 9.4e-13 47.6 0.0 9.9e-13 47.6 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain HSP70 PF00012.20 EGB05597.1 - 1.8e-197 657.2 0.4 2.2e-197 656.9 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGB05597.1 - 1e-14 54.2 0.9 2.3e-14 53.0 0.2 1.8 2 0 0 2 2 2 1 MreB/Mbl protein MutL PF13941.6 EGB05597.1 - 0.016 13.9 0.2 0.74 8.3 0.0 2.3 2 1 0 2 2 2 0 MutL protein FGGY_C PF02782.16 EGB05597.1 - 0.056 13.2 0.7 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EGB05597.1 - 0.12 12.8 0.4 24 5.4 0.0 3.2 3 1 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 EGB05597.1 - 0.16 11.1 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 StbA protein Nuc_sug_transp PF04142.15 EGB05598.1 - 2.8e-40 138.4 1.4 3.5e-40 138.1 1.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB05598.1 - 0.00011 22.4 1.6 0.00011 22.4 1.6 2.4 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 EGB05598.1 - 0.00036 19.8 0.1 0.00045 19.5 0.1 1.4 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EGB05598.1 - 0.02 14.1 0.3 0.036 13.3 0.3 1.6 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport ATPase_gene1 PF09527.10 EGB05598.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.8 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF1997 PF09366.10 EGB05599.1 - 1.7e-31 109.4 0.0 1.9e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) VERL PF11386.8 EGB05599.1 - 0.19 11.9 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin LRR_9 PF14580.6 EGB05600.1 - 9.3e-53 178.3 0.0 1.2e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGB05600.1 - 8.4e-12 45.1 8.6 1.1e-06 28.9 0.3 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB05600.1 - 8.7e-07 28.6 3.4 3.7e-06 26.6 1.1 2.3 1 1 1 2 2 2 1 Leucine rich repeat GA PF01468.17 EGB05600.1 - 0.0056 16.9 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 GA module PAS_9 PF13426.7 EGB05601.1 - 9.7e-11 41.8 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGB05601.1 - 4.6e-09 36.3 0.0 6.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EGB05601.1 - 3.7e-08 33.2 0.0 6.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EGB05601.1 - 0.0001 22.5 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold Calx-beta PF03160.14 EGB05602.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Calx-beta domain HSF_DNA-bind PF00447.17 EGB05603.1 - 1.3e-26 93.0 0.1 1.5e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding WW PF00397.26 EGB05604.1 - 3.9e-15 55.6 9.7 7.3e-09 35.6 0.5 2.5 2 0 0 2 2 2 2 WW domain zf-C2HC_2 PF13913.6 EGB05604.1 - 0.00075 19.3 0.3 0.0017 18.2 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type PALP PF00291.25 EGB05605.1 - 1.4e-60 205.2 2.5 1.7e-60 204.9 2.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Metallophos PF00149.28 EGB05607.1 - 7.8e-24 85.3 0.3 1.2e-23 84.7 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 EGB05607.1 - 1.3e-13 51.2 0.0 3.4e-08 33.8 0.0 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB05607.1 - 1.8e-10 39.6 0.0 0.009 15.5 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EGB05607.1 - 2.2e-09 36.5 0.0 0.0072 16.2 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EGB05607.1 - 3.1e-06 26.9 0.1 0.002 17.9 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB05607.1 - 3.1e-05 23.3 0.0 0.018 14.5 0.0 3.1 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EGB05607.1 - 0.48 10.8 3.6 0.28 11.5 1.4 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Aminotran_3 PF00202.21 EGB05608.1 - 6.9e-108 360.9 0.0 8.4e-108 360.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PSI_PsaF PF02507.15 EGB05609.1 - 1.3e-61 207.4 0.0 1.6e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit III NAD_Gly3P_dh_N PF01210.23 EGB05610.1 - 1e-28 100.3 0.1 1.7e-28 99.6 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EGB05610.1 - 1.3e-23 83.8 0.1 3.4e-23 82.5 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EGB05610.1 - 4.8e-06 27.1 0.1 1.3e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGB05610.1 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PDH PF02153.17 EGB05610.1 - 0.25 10.3 0.0 0.35 9.8 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase adh_short_C2 PF13561.6 EGB05611.1 - 2.3e-52 177.9 4.3 2.7e-52 177.7 4.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB05611.1 - 2e-41 141.6 1.1 2.7e-41 141.2 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB05611.1 - 2.2e-13 50.5 1.9 4.2e-13 49.6 1.9 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB05611.1 - 4.6e-09 36.1 0.7 2e-08 34.0 0.7 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB05611.1 - 0.00072 19.5 3.0 0.001 19.0 2.8 1.7 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGB05611.1 - 0.0021 17.2 0.3 0.003 16.7 0.3 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGB05611.1 - 0.007 15.8 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 EGB05611.1 - 0.0091 16.0 2.2 0.012 15.6 0.9 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 EGB05611.1 - 0.01 15.0 0.1 0.014 14.6 0.1 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EGB05611.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 EGB05611.1 - 0.03 13.3 0.0 0.051 12.6 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGB05611.1 - 0.055 12.6 1.5 1.1 8.4 0.2 2.5 1 1 1 3 3 3 0 Male sterility protein NmrA PF05368.13 EGB05611.1 - 0.085 12.4 4.4 0.12 11.9 1.6 2.3 2 2 0 2 2 2 0 NmrA-like family Methyltransf_11 PF08241.12 EGB05611.1 - 0.087 13.5 0.1 1.8 9.3 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DFP PF04127.15 EGB05611.1 - 0.089 12.6 3.0 0.088 12.6 0.4 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein FKBP_C PF00254.28 EGB05612.1 - 1.2e-21 76.8 0.0 1.7e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DnaJ PF00226.31 EGB05613.1 - 5.6e-24 84.0 5.4 6.7e-24 83.8 5.4 1.1 1 0 0 1 1 1 1 DnaJ domain Cupin_8 PF13621.6 EGB05614.1 - 1.5e-20 74.0 0.0 3.9e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain DnaJ PF00226.31 EGB05614.1 - 2.8e-11 43.3 4.2 3.1e-11 43.2 0.1 3.0 4 0 0 4 4 4 1 DnaJ domain Cupin_4 PF08007.12 EGB05614.1 - 4.7e-08 32.9 0.0 1.5e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Cupin superfamily protein PDZ_6 PF17820.1 EGB05614.1 - 6.5e-05 22.7 0.1 0.00016 21.5 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGB05614.1 - 0.0067 16.8 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Cupin_1 PF00190.22 EGB05614.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 EGB05614.1 - 0.16 11.7 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Cupin domain TPR_2 PF07719.17 EGB05614.1 - 6.7 7.1 7.1 10 6.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 EGB05616.1 - 4e-06 26.7 0.0 5.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 EGB05616.1 - 0.0047 16.6 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase PF06745.13 EGB05616.1 - 0.023 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EGB05616.1 - 0.038 14.3 0.2 0.11 12.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGB05616.1 - 0.042 13.4 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB05616.1 - 0.047 13.2 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 EGB05616.1 - 0.047 12.7 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EGB05616.1 - 0.068 13.5 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB05616.1 - 0.068 13.6 1.0 0.22 11.9 1.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Ploopntkinase1 PF18748.1 EGB05616.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 Rad17 PF03215.15 EGB05616.1 - 0.25 11.3 0.0 0.47 10.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DAO PF01266.24 EGB05617.1 - 4.7e-59 200.7 8.0 1.2e-58 199.4 8.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pkinase PF00069.25 EGB05617.1 - 6e-57 193.0 0.0 7.6e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05617.1 - 6.9e-30 104.2 0.0 9.4e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_2 PF00890.24 EGB05617.1 - 1.9e-08 33.8 0.6 7e-08 32.0 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB05617.1 - 2.9e-05 23.5 0.1 0.0013 18.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGB05617.1 - 3.6e-05 23.1 0.1 6.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Kinase-like PF14531.6 EGB05617.1 - 4.9e-05 22.8 0.0 8.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NAD_binding_8 PF13450.6 EGB05617.1 - 6.2e-05 23.1 0.3 0.00027 21.1 0.2 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Haspin_kinase PF12330.8 EGB05617.1 - 9.7e-05 21.5 0.8 0.00014 20.9 0.8 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FAD_binding_3 PF01494.19 EGB05617.1 - 0.00018 20.9 0.8 0.00031 20.1 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Kdo PF06293.14 EGB05617.1 - 0.00092 18.6 0.3 0.0017 17.7 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox PF00070.27 EGB05617.1 - 0.00097 19.7 0.1 0.032 14.8 0.1 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGB05617.1 - 0.0017 17.8 1.4 0.0034 16.8 1.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGB05617.1 - 0.0028 16.4 0.3 0.014 14.2 0.3 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGB05617.1 - 0.0071 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB05617.1 - 0.012 14.7 0.7 0.036 13.1 0.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pkinase_fungal PF17667.1 EGB05617.1 - 0.017 13.9 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Lycopene_cycl PF05834.12 EGB05617.1 - 0.092 11.8 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FTA2 PF13095.6 EGB05617.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Trp_halogenase PF04820.14 EGB05617.1 - 0.27 10.0 0.6 9.3 5.0 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Methyltransf_24 PF13578.6 EGB05619.1 - 1.2e-09 39.1 0.2 2.6e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EGB05619.1 - 8.4e-05 22.3 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_12 PF08242.12 EGB05619.1 - 0.00011 22.9 0.0 0.00021 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05619.1 - 0.00053 19.8 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGB05619.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ion_trans PF00520.31 EGB05620.1 - 5.7e-17 61.8 0.5 1.3e-16 60.6 0.5 1.7 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB05620.1 - 2.9e-11 43.3 0.0 9e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Arylsulfotrans PF05935.11 EGB05620.1 - 4.2e-11 42.4 0.0 8.3e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB05620.1 - 0.0046 16.4 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DUF1179 PF06678.11 EGB05621.1 - 0.17 11.9 3.9 4.6 7.3 3.9 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1179) Fez1 PF06818.15 EGB05621.1 - 1.2 9.5 3.5 3 8.2 3.5 1.7 1 1 0 1 1 1 0 Fez1 DUF3584 PF12128.8 EGB05621.1 - 8.9 3.7 6.8 16 2.8 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PAS_9 PF13426.7 EGB05622.1 - 1.8e-13 50.6 0.0 1.9e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGB05622.1 - 0.0015 18.5 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EGB05623.1 - 1.5e-14 54.1 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGB05623.1 - 4.1e-05 23.5 0.0 5.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EGB05623.1 - 0.0067 16.7 0.0 0.0084 16.4 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGB05623.1 - 0.093 13.0 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 PAS fold DEAD PF00270.29 EGB05624.1 - 4.1e-41 140.7 0.0 3.9e-40 137.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB05624.1 - 9.6e-29 100.0 0.0 3.4e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB05624.1 - 0.00048 20.2 0.0 0.0026 17.8 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Consortin_C PF15281.6 EGB05624.1 - 0.043 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Consortin C-terminus UTP25 PF06862.12 EGB05624.1 - 0.1 11.4 0.0 5.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_30 PF13604.6 EGB05624.1 - 0.11 12.1 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain EamA PF00892.20 EGB05625.1 - 6.7e-18 65.2 26.7 6.9e-12 45.7 5.8 2.7 3 1 0 3 3 3 2 EamA-like transporter family DUF1294 PF06961.13 EGB05625.1 - 0.23 11.7 0.9 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) SNF2_N PF00176.23 EGB05626.1 - 9.6e-57 192.3 0.0 1.3e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB05626.1 - 9.2e-17 61.4 0.0 3.3e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB05626.1 - 0.0014 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rhodanese PF00581.20 EGB05626.1 - 0.024 15.2 0.0 0.47 11.0 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain FGGY_N PF00370.21 EGB05627.1 - 8.7e-16 58.2 0.0 7.8e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGB05627.1 - 8.8e-15 55.0 0.7 2e-14 53.8 0.7 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain APH PF01636.23 EGB05628.1 - 2.1e-07 31.2 22.4 4.1e-06 26.9 22.4 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_1 PF00036.32 EGB05629.1 - 4.4e-09 35.2 0.3 0.00016 20.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB05629.1 - 7.2e-09 34.9 0.2 0.00046 19.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB05629.1 - 1.2e-08 34.0 0.5 0.00014 21.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB05629.1 - 4.1e-07 30.4 0.5 7.6e-07 29.5 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB05629.1 - 4.1e-07 29.7 1.3 0.0078 16.0 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair AhpC-TSA PF00578.21 EGB05629.1 - 5.9e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGB05629.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Redoxin Condensin2nSMC PF12422.8 EGB05631.1 - 1.1e-21 77.6 0.0 1.9e-12 47.6 0.0 2.6 2 0 0 2 2 2 2 Condensin II non structural maintenance of chromosomes subunit PBP1_TM PF14812.6 EGB05631.1 - 0.31 11.5 3.6 0.68 10.3 3.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IMUP PF15761.5 EGB05631.1 - 8.6 7.1 18.4 7.1 7.4 7.3 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein ABC_tran PF00005.27 EGB05632.1 - 5.5e-43 146.8 0.1 1.6e-22 80.5 0.0 3.9 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGB05632.1 - 8.7e-12 45.0 6.2 0.00014 21.4 0.1 4.1 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGB05632.1 - 4.7e-11 43.0 0.0 0.12 12.2 0.0 4.3 4 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EGB05632.1 - 2e-07 31.4 0.0 0.00062 20.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EGB05632.1 - 2.5e-05 24.9 1.4 0.058 13.9 0.9 2.6 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGB05632.1 - 6.3e-05 22.6 0.3 0.041 13.6 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB05632.1 - 9.7e-05 22.4 0.0 0.012 15.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 EGB05632.1 - 0.00021 21.5 0.2 0.088 13.1 0.0 3.8 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EGB05632.1 - 0.00099 19.0 0.1 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGB05632.1 - 0.0014 18.9 0.2 0.17 12.2 0.1 3.1 3 1 0 4 4 3 1 AAA domain AAA PF00004.29 EGB05632.1 - 0.0021 18.5 0.0 3.1 8.2 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EGB05632.1 - 0.0029 17.4 0.1 3.5 7.2 0.1 2.8 3 1 0 3 3 3 2 AAA ATPase domain G-alpha PF00503.20 EGB05632.1 - 0.0047 16.1 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 EGB05632.1 - 0.005 16.8 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 EGB05632.1 - 0.0076 16.0 0.0 3.7 7.3 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EGB05632.1 - 0.0076 16.4 0.3 0.099 12.8 0.4 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGB05632.1 - 0.0085 16.5 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 EGB05632.1 - 0.013 15.5 0.0 4.5 7.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGB05632.1 - 0.021 14.4 0.1 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGB05632.1 - 0.026 14.2 0.0 0.79 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGB05632.1 - 0.027 14.7 0.0 6.3 7.0 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 EGB05632.1 - 0.043 13.6 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 EGB05632.1 - 0.051 14.0 0.1 0.79 10.1 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain FeoB_N PF02421.18 EGB05632.1 - 0.085 12.4 0.4 3.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 EGB05632.1 - 0.12 12.2 0.2 11 5.9 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EGB05632.1 - 0.16 11.9 0.1 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RCC1 PF00415.18 EGB05633.1 - 8.1e-41 138.4 19.4 1.1e-11 45.2 0.9 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB05633.1 - 2.1e-22 78.4 23.5 0.00023 20.8 0.5 5.9 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat JmjC PF02373.22 EGB05634.1 - 2.9e-07 30.9 0.0 7.7e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGB05634.1 - 0.01 15.5 0.0 0.15 11.8 0.0 2.3 3 0 0 3 3 3 0 Cupin-like domain CHORD PF04968.12 EGB05635.1 - 1.9e-21 76.5 17.5 2.2e-21 76.4 17.5 1.0 1 0 0 1 1 1 1 CHORD Chloroa_b-bind PF00504.21 EGB05636.1 - 2.4e-30 106.2 1.1 3.1e-30 105.8 1.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Sulfatase PF00884.23 EGB05637.1 - 2.1e-63 214.6 0.1 2.6e-63 214.3 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB05637.1 - 9.4e-06 25.4 0.0 0.064 12.8 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EGB05637.1 - 0.054 14.2 0.0 0.095 13.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase EF-hand_7 PF13499.6 EGB05638.1 - 3.1e-05 24.3 0.0 3.1e-05 24.3 0.0 2.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB05638.1 - 0.01 15.6 0.1 0.01 15.6 0.1 3.5 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_1 PF00036.32 EGB05638.1 - 0.011 15.2 0.1 0.011 15.2 0.1 5.2 5 0 0 5 5 5 0 EF hand EF-hand_5 PF13202.6 EGB05638.1 - 0.015 14.8 0.1 0.015 14.8 0.1 5.6 7 0 0 7 7 7 0 EF hand EF-hand_6 PF13405.6 EGB05638.1 - 0.12 12.4 0.0 0.12 12.4 0.0 5.1 6 0 0 6 6 6 0 EF-hand domain DnaJ_C PF01556.18 EGB05638.1 - 0.15 12.1 0.0 1.7 8.7 0.0 2.4 1 1 1 2 2 2 0 DnaJ C terminal domain VCBS PF13517.6 EGB05638.1 - 2.2 9.0 18.2 7.8 7.2 0.0 5.5 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EGB05638.1 - 6.8 6.0 7.6 16 4.8 0.1 3.3 1 1 3 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region FAD_binding_4 PF01565.23 EGB05639.1 - 9.3e-23 80.5 3.9 1.1e-22 80.3 2.7 1.7 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 EGB05639.1 - 2e-17 63.9 0.0 5.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FKBP_C PF00254.28 EGB05640.1 - 3.1e-15 56.3 0.0 3.6e-05 24.0 0.0 4.2 3 1 1 4 4 4 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EGB05640.1 - 0.29 11.4 12.0 1 9.6 1.8 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 EGB05641.1 - 7.3e-28 97.3 0.0 9.5e-27 93.7 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGB05641.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II DUF4205 PF13898.6 EGB05642.1 - 2.7e-08 33.1 0.0 1.4e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4205) UBA_4 PF14555.6 EGB05642.1 - 1.6e-05 24.6 0.0 3.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain INCENP_ARK-bind PF03941.15 EGB05643.1 - 0.0002 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Rad60-SLD PF11976.8 EGB05643.1 - 0.064 13.1 0.0 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like NeuB PF03102.14 EGB05644.1 - 1.2e-56 191.9 0.0 1.4e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 NeuB family AAA_28 PF13521.6 EGB05645.1 - 7e-21 75.2 0.0 8.9e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EGB05645.1 - 0.00024 20.2 0.6 0.00061 18.9 0.3 1.6 1 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 EGB05645.1 - 0.0041 16.6 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EGB05645.1 - 0.011 16.3 0.1 0.019 15.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGB05645.1 - 0.012 15.5 0.2 0.023 14.6 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 EGB05645.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain GDC-P PF02347.16 EGB05646.1 - 1.5e-166 554.6 5.0 3.5e-155 517.1 0.2 3.0 2 1 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EGB05646.1 - 5.2e-05 22.4 1.7 0.00079 18.5 0.1 2.8 2 2 1 3 3 3 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGB05646.1 - 0.00017 21.0 0.1 0.00031 20.1 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase EXS PF03124.14 EGB05647.1 - 2.8e-50 171.5 0.4 3.9e-50 171.0 0.4 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EGB05647.1 - 7.8e-19 68.8 5.2 4.6e-08 33.4 0.0 4.1 3 1 1 4 4 4 4 SPX domain CK2S PF15011.6 EGB05647.1 - 0.0009 19.2 0.1 0.0019 18.1 0.1 1.5 1 0 0 1 1 1 1 Casein Kinase 2 substrate EF-hand_6 PF13405.6 EGB05648.1 - 3.5e-13 48.3 0.1 0.0046 16.8 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 EGB05648.1 - 3.8e-10 38.6 0.0 0.052 13.1 0.0 4.0 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGB05648.1 - 1.4e-09 38.3 0.0 0.014 15.8 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain pair Gal-3-0_sulfotr PF06990.11 EGB05648.1 - 1.2e-06 27.7 2.8 0.011 14.6 0.2 2.5 1 1 1 2 2 2 2 Galactose-3-O-sulfotransferase EF-hand_8 PF13833.6 EGB05648.1 - 0.03 14.2 0.1 63 3.5 0.0 3.6 3 1 1 4 4 4 0 EF-hand domain pair GST_N PF02798.20 EGB05649.1 - 1.6e-08 34.7 0.0 3.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB05649.1 - 3.6e-08 33.5 0.0 6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB05649.1 - 2.2e-07 30.8 3.3 2.7e-07 30.5 2.4 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB05649.1 - 1e-05 25.8 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB05649.1 - 2.1e-05 24.8 0.0 5.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB05649.1 - 0.00074 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain His_Phos_1 PF00300.22 EGB05650.1 - 3.3e-29 102.0 0.0 5.9e-26 91.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 EGB05651.1 - 4.7e-31 108.0 0.1 3.2e-25 89.0 0.2 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) BCCT PF02028.17 EGB05652.1 - 5.7e-146 486.8 23.0 6.6e-146 486.6 23.0 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter Chordopox_A13L PF05961.11 EGB05652.1 - 0.98 9.7 3.0 5.1 7.4 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Arylsulfotrans PF05935.11 EGB05653.1 - 6.9e-10 38.4 0.1 1.1e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Ribosomal_S8e PF01201.22 EGB05655.1 - 6e-53 178.7 2.9 7.1e-53 178.5 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Oscp1 PF10188.9 EGB05656.1 - 2.5e-43 148.2 0.8 3.3e-43 147.8 0.8 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 RRM_1 PF00076.22 EGB05657.1 - 3.7e-07 29.9 0.1 0.17 11.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.27 EGB05657.1 - 5.1e-05 23.1 0.0 8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF563 PF04577.14 EGB05658.1 - 2.5e-13 50.6 0.0 6.1e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Tyrosinase PF00264.20 EGB05659.1 - 1.4e-12 48.4 1.9 7.6e-09 36.2 0.4 2.2 2 0 0 2 2 2 2 Common central domain of tyrosinase PKD PF00801.20 EGB05659.1 - 2.7e-05 23.9 0.2 7.6e-05 22.5 0.2 1.9 1 0 0 1 1 1 1 PKD domain GTP_EFTU PF00009.27 EGB05660.1 - 1.5e-25 89.9 0.0 1.8e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGB05660.1 - 0.0044 17.1 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB05660.1 - 0.019 14.9 0.0 0.052 13.5 0.0 1.7 1 1 1 2 2 2 0 RsgA GTPase Amidohydro_1 PF01979.20 EGB05661.1 - 3.4e-62 210.7 0.2 4.4e-62 210.4 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGB05661.1 - 3e-07 30.3 0.2 1.3e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase family Rhodanese_C PF12368.8 EGB05662.1 - 8.9e-15 54.8 5.8 8.9e-15 54.8 5.8 1.9 2 0 0 2 2 2 1 Rhodanase C-terminal UPF0176_N PF17773.1 EGB05662.1 - 5e-09 36.4 0.0 8.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 EGB05662.1 - 2.1e-05 25.0 1.3 5.4e-05 23.7 0.0 2.4 3 1 0 3 3 3 1 Rhodanese-like domain Sigma70_r3 PF04539.16 EGB05662.1 - 0.0018 18.3 0.2 0.0034 17.4 0.2 1.3 1 0 0 1 1 1 1 Sigma-70 region 3 RNA_pol_Rpc4 PF05132.14 EGB05662.1 - 0.06 13.8 3.3 0.11 13.0 3.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ribosomal_L44 PF00935.19 EGB05663.1 - 9.3e-35 118.9 14.2 1.6e-34 118.2 14.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 SVWC PF15430.6 EGB05663.1 - 0.048 13.9 3.9 0.29 11.4 0.6 2.2 2 0 0 2 2 2 0 Single domain von Willebrand factor type C Lzipper-MIP1 PF14389.6 EGB05664.1 - 0.68 10.3 17.1 6.5 7.1 2.7 6.4 5 1 1 6 6 6 0 Leucine-zipper of ternary complex factor MIP1 Syntaxin_2 PF14523.6 EGB05664.1 - 1.4 9.3 12.5 3.3 8.1 0.1 5.0 4 1 2 6 6 6 0 Syntaxin-like protein Baculo_PEP_C PF04513.12 EGB05664.1 - 3.9 7.5 13.5 2.6 8.1 0.8 4.5 6 0 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EGB05664.1 - 5.7 7.0 21.8 0.32 11.1 0.5 6.3 6 1 0 6 6 6 0 Protein of unknown function (DUF1664) SET PF00856.28 EGB05665.1 - 4.7e-23 82.4 0.0 1.6e-22 80.7 0.0 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 EGB05665.1 - 8.1e-14 52.2 5.2 8.1e-14 52.2 5.2 1.6 2 0 0 2 2 2 1 Pre-SET motif Aldose_epim PF01263.20 EGB05666.1 - 9.1e-35 120.4 0.0 1.1e-34 120.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AAA PF00004.29 EGB05667.1 - 1.6e-11 44.7 1.2 1.7e-11 44.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB05667.1 - 1.2e-07 32.3 1.1 9.7e-05 22.8 0.3 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EGB05667.1 - 2e-07 31.1 0.0 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EGB05667.1 - 5.9e-06 26.3 0.0 0.00095 19.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 EGB05667.1 - 9.4e-06 26.2 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB05667.1 - 1e-05 25.3 0.5 1e-05 25.3 0.5 1.6 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EGB05667.1 - 1.6e-05 25.2 0.3 0.00071 19.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGB05667.1 - 0.00026 20.8 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EGB05667.1 - 0.00048 19.8 0.5 0.0027 17.3 0.1 2.1 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 EGB05667.1 - 0.00066 19.6 0.2 0.0061 16.5 0.1 2.1 1 1 1 2 2 2 1 NACHT domain AAA_28 PF13521.6 EGB05667.1 - 0.00088 19.5 0.8 0.0023 18.2 0.8 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGB05667.1 - 0.0013 18.7 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGB05667.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGB05667.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGB05667.1 - 0.0023 17.9 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 NTPase TsaE PF02367.17 EGB05667.1 - 0.0031 17.5 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EGB05667.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 KaiC Zeta_toxin PF06414.12 EGB05667.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 EGB05667.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 EGB05667.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EGB05667.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGB05667.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EGB05667.1 - 0.022 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 EGB05667.1 - 0.027 14.6 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 EGB05667.1 - 0.03 13.5 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EGB05667.1 - 0.035 14.6 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 EGB05667.1 - 0.051 13.3 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EGB05667.1 - 0.057 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 EGB05667.1 - 0.06 13.2 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 EGB05667.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 EGB05667.1 - 0.074 13.4 1.9 0.093 13.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 EGB05667.1 - 0.09 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Mg_chelatase PF01078.21 EGB05667.1 - 0.1 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EGB05667.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EGB05667.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 EGB05667.1 - 0.16 12.4 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGB05667.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EGB05667.1 - 0.32 11.4 0.0 0.32 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain Pkinase PF00069.25 EGB05668.1 - 7.5e-15 55.0 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05668.1 - 0.00023 20.5 0.0 0.0011 18.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB05668.1 - 0.052 12.9 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FKBP_C PF00254.28 EGB05669.1 - 4.7e-34 116.6 0.0 5.4e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ABC_tran PF00005.27 EGB05670.1 - 0.0033 17.9 0.0 0.0037 17.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGB05671.1 - 3e-20 73.0 0.0 3.6e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region VCBS PF13517.6 EGB05672.1 - 1.6e-16 60.6 42.4 1.4e-07 32.0 4.4 7.5 5 2 1 6 6 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 EGB05672.1 - 8.2e-14 51.6 135.6 0.0012 19.1 1.4 15.6 15 0 0 15 15 14 10 FG-GAP repeat REJ PF02010.15 EGB05672.1 - 6.9e-12 44.9 0.0 1e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 REJ domain zf-RING_2 PF13639.6 EGB05672.1 - 1e-08 35.4 1.3 2.4e-08 34.2 1.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGB05672.1 - 8.7e-08 32.3 1.4 2e-07 31.2 1.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain FG-GAP PF01839.23 EGB05672.1 - 1.4e-07 31.5 58.8 0.00021 21.4 1.5 11.4 10 0 0 10 10 9 4 FG-GAP repeat zf-C3HC4_2 PF13923.6 EGB05672.1 - 1.4e-05 24.9 4.0 4.7e-05 23.1 4.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGB05672.1 - 0.00012 21.7 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger PT PF04886.12 EGB05672.1 - 0.00012 21.5 50.9 0.0002 20.8 14.1 16.9 10 3 4 14 14 11 6 PT repeat zf-C3HC4 PF00097.25 EGB05672.1 - 0.00037 20.3 1.2 0.00072 19.4 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB05672.1 - 0.002 18.1 1.1 0.0041 17.1 1.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger RCC1_2 PF13540.6 EGB05672.1 - 0.0058 16.4 21.4 6.7 6.6 0.3 8.0 8 0 0 8 8 8 1 Regulator of chromosome condensation (RCC1) repeat NCD3G PF07562.14 EGB05672.1 - 0.0063 16.5 7.1 5.5 7.1 0.1 3.8 3 0 0 3 3 3 2 Nine Cysteines Domain of family 3 GPCR zf-C3HC4_3 PF13920.6 EGB05672.1 - 0.011 15.6 1.3 0.028 14.3 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TcdB_toxin_midN PF12256.8 EGB05672.1 - 0.014 14.7 7.4 5.7 6.3 0.1 5.2 5 0 0 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region Zn_ribbon_17 PF17120.5 EGB05672.1 - 0.022 14.4 1.7 0.07 12.8 1.7 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGB05672.1 - 0.039 14.0 0.2 0.19 11.8 0.2 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGB05672.1 - 0.096 12.7 1.5 0.22 11.5 1.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Ephrin_rec_like PF07699.13 EGB05672.1 - 9.5 6.1 14.7 4.4 7.1 0.0 4.4 5 0 0 5 5 4 0 Putative ephrin-receptor like AAA_12 PF13087.6 EGB05673.1 - 1.1e-22 80.6 0.2 1.3e-22 80.4 0.2 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB05673.1 - 0.00022 21.0 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain FAA_hydrolase PF01557.18 EGB05674.1 - 2.8e-39 135.1 0.0 3.3e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cyt-b5 PF00173.28 EGB05675.1 - 4.3e-07 30.0 0.1 6.5e-07 29.4 0.1 1.5 1 1 1 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NUP50 PF08911.11 EGB05675.1 - 0.3 11.8 1.2 0.48 11.1 1.2 1.2 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) RINGv PF12906.7 EGB05676.1 - 5.6e-08 32.8 3.1 1.2e-07 31.7 3.1 1.6 1 0 0 1 1 1 1 RING-variant domain DUF179 PF02622.15 EGB05676.1 - 0.00023 21.2 0.0 0.00051 20.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Sel1 PF08238.12 EGB05677.1 - 3.2e-23 81.7 12.6 3.8e-10 40.1 0.1 4.5 4 1 0 4 4 4 3 Sel1 repeat DUF3686 PF12458.8 EGB05677.1 - 0.0073 14.9 0.0 0.0086 14.6 0.0 1.0 1 0 0 1 1 1 1 ATPase involved in DNA repair TPR_14 PF13428.6 EGB05677.1 - 0.046 14.6 6.5 7.6 7.6 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05677.1 - 0.12 13.0 11.2 9.3 7.0 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05677.1 - 0.33 10.7 2.8 24 4.7 0.2 3.4 3 1 0 3 3 3 0 TPR repeat TPR_2 PF07719.17 EGB05677.1 - 0.37 11.0 14.0 8.6 6.8 0.2 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB05677.1 - 0.44 10.5 6.7 7.3 6.6 1.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05677.1 - 2 8.4 10.6 45 4.1 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat PI-PLC-X PF00388.19 EGB05678.1 - 3.2e-47 159.8 0.0 4e-46 156.2 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGB05678.1 - 8.3e-24 84.2 0.0 2.1e-23 82.9 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGB05678.1 - 1.1e-16 61.0 0.0 3.5e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain PHD PF00628.29 EGB05679.1 - 3.3e-14 52.5 3.3 5.6e-14 51.8 3.3 1.4 1 0 0 1 1 1 1 PHD-finger PhyH PF05721.13 EGB05679.1 - 4.9e-11 43.3 0.0 9.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PHD_2 PF13831.6 EGB05679.1 - 0.00054 19.5 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 EGB05679.1 - 0.00097 19.4 0.6 0.0022 18.3 0.6 1.6 1 0 0 1 1 1 1 C1 domain zf-PHD-like PF15446.6 EGB05679.1 - 0.074 12.7 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 EGB05679.1 - 0.12 12.8 5.1 0.2 12.0 5.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_9 PF13901.6 EGB05679.1 - 0.21 11.6 0.9 0.34 10.9 0.9 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD_4 PF16866.5 EGB05679.1 - 0.56 10.3 5.0 1.4 9.1 5.0 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EGB05679.1 - 1.1 9.2 10.3 0.04 13.8 3.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 EGB05679.1 - 1.5 8.9 6.8 12 6.0 2.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon CH PF00307.31 EGB05680.1 - 2.1e-13 50.4 0.0 2.3e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain ASF1_hist_chap PF04729.13 EGB05681.1 - 1.3e-54 184.3 0.0 1.6e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Ysc84 PF04366.12 EGB05682.1 - 2e-29 101.9 0.5 2.6e-29 101.6 0.5 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator Metallophos PF00149.28 EGB05683.1 - 5.1e-12 46.7 0.0 6.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB05683.1 - 1.1e-06 29.0 0.1 1.7e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_34 PF13872.6 EGB05684.1 - 3e-116 387.6 0.0 4.5e-116 387.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ResIII PF04851.15 EGB05684.1 - 0.0027 17.7 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arm PF00514.23 EGB05685.1 - 2.2e-33 113.3 14.9 1.4e-07 31.3 0.5 6.4 6 1 0 6 6 6 5 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EGB05685.1 - 1e-06 28.4 0.2 0.0033 16.9 0.3 3.2 2 1 0 2 2 2 2 Armadillo-like HEAT_2 PF13646.6 EGB05685.1 - 2.2e-06 28.0 8.0 0.037 14.4 0.2 3.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EGB05685.1 - 0.00091 19.3 5.0 0.17 12.3 0.0 4.7 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EGB05685.1 - 0.0012 19.3 15.8 0.54 10.8 0.1 5.0 2 1 3 5 5 5 2 HEAT-like repeat KAP PF05804.12 EGB05685.1 - 0.036 12.2 0.0 0.42 8.7 0.0 2.1 1 1 1 2 2 2 0 Kinesin-associated protein (KAP) Sel1 PF08238.12 EGB05687.1 - 2.4e-45 151.9 28.3 3.9e-08 33.7 0.4 8.4 8 0 0 8 8 8 8 Sel1 repeat DUF977 PF06163.11 EGB05687.1 - 6.5e-07 29.3 1.0 0.17 11.9 0.1 3.7 3 1 1 4 4 4 2 Bacterial protein of unknown function (DUF977) TPR_16 PF13432.6 EGB05687.1 - 0.00058 20.5 27.4 0.065 13.9 1.2 6.4 7 1 1 8 8 7 2 Tetratricopeptide repeat DUF4715 PF15835.5 EGB05687.1 - 0.0034 17.5 0.2 5.6 7.0 0.0 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF4715) DUF3228 PF11539.8 EGB05687.1 - 0.13 11.8 0.1 6.5 6.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3228) VIT PF08487.10 EGB05687.1 - 0.16 12.2 3.8 38 4.5 0.0 4.1 3 1 1 4 4 4 0 Vault protein inter-alpha-trypsin domain MIT PF04212.18 EGB05687.1 - 0.23 11.6 9.7 8.3 6.6 0.1 4.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EGB05687.1 - 0.27 11.5 0.2 0.27 11.5 0.2 6.0 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05687.1 - 0.74 9.7 0.0 0.74 9.7 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB05687.1 - 1.7 9.6 18.4 14 6.8 0.0 6.8 5 3 3 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05687.1 - 6 7.4 20.2 4.4 7.8 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PP2C PF00481.21 EGB05688.1 - 4.7e-40 137.8 0.0 6.3e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB05688.1 - 4.2e-08 33.3 0.0 0.00022 21.2 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGB05688.1 - 6.5e-06 25.9 0.0 3.3e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2380 PF09533.10 EGB05688.1 - 0.059 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) TRAPP PF04051.16 EGB05689.1 - 5.9e-36 123.4 0.0 6.5e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component IncFII_repA PF02387.15 EGB05689.1 - 0.016 14.5 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 IncFII RepA protein family Flavokinase PF01687.17 EGB05690.1 - 1.5e-29 102.5 0.0 1.8e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Amino_oxidase PF01593.24 EGB05691.1 - 1.6e-14 54.0 0.0 2.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB05691.1 - 1.6e-10 41.0 0.0 6e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGB05691.1 - 2e-08 33.8 1.0 1.3e-05 24.5 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGB05691.1 - 7.1e-05 22.5 0.0 0.049 13.2 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGB05691.1 - 0.00013 21.3 0.5 0.00025 20.4 0.5 1.4 1 0 0 1 1 1 1 Thi4 family GDI PF00996.18 EGB05691.1 - 0.00023 19.8 0.1 0.43 9.0 0.1 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_oxidored PF12831.7 EGB05691.1 - 0.00035 20.0 0.1 0.0012 18.3 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGB05691.1 - 0.0011 18.3 0.0 0.027 13.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB05691.1 - 0.0025 16.6 2.8 0.046 12.4 1.4 2.3 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGB05691.1 - 0.025 13.8 0.0 0.083 12.1 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB05691.1 - 0.045 12.8 1.8 1.5 7.8 0.9 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGB05691.1 - 0.11 13.0 0.3 1.6 9.3 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB05691.1 - 0.14 11.4 0.4 0.29 10.3 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain LRR_9 PF14580.6 EGB05693.1 - 5.8e-11 42.2 0.1 1.9e-10 40.5 0.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGB05693.1 - 4.5e-07 30.1 0.4 0.052 14.0 0.1 3.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB05693.1 - 3.2e-06 26.8 0.2 5.4e-05 22.9 0.0 2.6 3 0 0 3 3 3 1 Leucine rich repeat HA2 PF04408.23 EGB05694.1 - 6.7e-20 71.4 0.0 2e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGB05694.1 - 3.9e-13 49.6 0.0 7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGB05694.1 - 9.5e-11 42.0 0.0 2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB05694.1 - 6.1e-05 22.9 0.4 0.00024 20.9 0.4 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGB05694.1 - 0.00023 21.5 0.3 0.00082 19.7 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB05694.1 - 0.00024 20.9 0.1 0.00051 19.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGB05694.1 - 0.0039 16.3 0.0 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 EGB05694.1 - 0.018 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGB05694.1 - 0.021 15.2 0.3 0.049 14.0 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain Flavi_DEAD PF07652.14 EGB05694.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 EGB05694.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB05694.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EGB05694.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB05694.1 - 0.075 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EGB05694.1 - 0.094 13.2 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB05694.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.8 3 1 0 3 3 2 0 AAA domain ResIII PF04851.15 EGB05694.1 - 0.16 12.0 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit cobW PF02492.19 EGB05694.1 - 0.28 10.7 0.5 0.79 9.3 0.2 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain EF-hand_7 PF13499.6 EGB05695.1 - 2.1e-13 50.5 0.4 2.4e-11 43.9 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB05695.1 - 2.6e-10 39.1 3.2 6.8e-07 28.4 0.5 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB05695.1 - 6.3e-09 35.1 1.6 0.0029 17.4 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EGB05695.1 - 8.8e-07 28.7 5.7 4.6e-06 26.4 1.1 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 EGB05695.1 - 1.3e-06 28.7 0.3 3.2e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EGB05695.1 - 0.0015 17.9 0.9 0.0015 17.9 0.9 3.5 4 1 1 5 5 5 1 EF hand EF-hand_10 PF14788.6 EGB05695.1 - 0.014 15.3 0.5 0.027 14.4 0.2 1.7 2 0 0 2 2 2 0 EF hand EspA PF03433.13 EGB05695.1 - 0.033 14.1 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 EspA-like secreted protein Lip_prot_lig_C PF10437.9 EGB05695.1 - 0.099 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus RPN2_C PF18004.1 EGB05696.1 - 1.3e-29 103.2 0.2 4e-27 95.1 0.2 2.3 1 1 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGB05696.1 - 2.9e-26 90.5 25.5 0.0016 18.8 0.5 8.7 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGB05696.1 - 1e-18 67.5 0.9 9.3e-12 45.2 0.0 4.6 3 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EGB05696.1 - 0.00015 21.7 0.9 0.81 10.1 0.1 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EGB05696.1 - 0.038 14.5 4.0 0.093 13.3 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.20 EGB05696.1 - 0.097 11.2 0.8 2.8 6.4 0.1 2.6 2 1 1 3 3 3 0 Adaptin N terminal region Ribosomal_L21e PF01157.18 EGB05697.1 - 1.8e-44 149.7 4.1 3.3e-44 148.9 2.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e PIP5K PF01504.18 EGB05698.1 - 8.2e-47 159.7 0.3 1.1e-36 126.5 0.1 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase IMP2_N PF18590.1 EGB05699.1 - 2.8e-24 85.5 0.0 5.3e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 EGB05699.1 - 8.3e-07 28.8 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain SlyX PF04102.12 EGB05699.1 - 0.63 10.7 4.1 18 6.0 0.3 2.7 2 0 0 2 2 2 0 SlyX Methyltransf_25 PF13649.6 EGB05700.1 - 0.00079 20.1 0.0 0.0021 18.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB05700.1 - 0.013 16.2 0.1 0.038 14.6 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB05700.1 - 0.015 16.0 0.1 0.21 12.4 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGB05700.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGB05700.1 - 0.028 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RNA_pol_Rpb2_6 PF00562.28 EGB05701.1 - 2.4e-124 415.3 0.0 3.3e-124 414.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGB05701.1 - 8.9e-60 201.7 0.1 6.2e-34 117.3 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGB05701.1 - 8.9e-48 162.4 0.1 1.6e-47 161.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGB05701.1 - 7.9e-27 93.5 0.0 2.2e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGB05701.1 - 1.9e-26 92.0 0.0 4.7e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EGB05701.1 - 1.1e-24 86.4 0.1 2.9e-24 85.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGB05701.1 - 1.3e-16 60.9 0.8 3.3e-16 59.6 0.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Agenet PF05641.12 EGB05701.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Agenet domain 2OG-FeII_Oxy_3 PF13640.6 EGB05702.1 - 3.6e-10 40.6 0.0 1.2e-09 39.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB05702.1 - 3.3e-05 24.5 0.0 8.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Baculo_PEP_C PF04513.12 EGB05702.1 - 0.034 14.2 1.0 0.33 11.0 0.1 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2959 PF11172.8 EGB05702.1 - 0.17 12.0 6.5 0.044 13.9 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Mer2 PF09074.10 EGB05702.1 - 1 9.1 7.1 12 5.6 6.2 2.7 2 1 1 3 3 3 0 Mer2 Phasin PF05597.11 EGB05702.1 - 3.8 7.5 11.4 0.12 12.4 3.8 2.3 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pkinase PF00069.25 EGB05703.1 - 5.6e-58 196.4 0.1 4.5e-56 190.1 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05703.1 - 9e-23 80.9 0.0 8.5e-16 58.0 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGB05703.1 - 0.00016 21.1 0.2 0.00025 20.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB05703.1 - 0.0075 15.6 0.1 1.4 8.1 0.0 3.1 3 0 0 3 3 3 1 Kinase-like Pox_ser-thr_kin PF05445.11 EGB05703.1 - 0.12 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dynamin_M PF01031.20 EGB05704.1 - 1.4e-42 145.9 0.7 2e-42 145.4 0.7 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGB05704.1 - 5.1e-36 124.3 0.0 9.2e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family PDZ_6 PF17820.1 EGB05704.1 - 8.8e-09 35.1 0.0 3.7e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EGB05704.1 - 2.7e-06 27.6 0.4 5.8e-06 26.6 0.4 1.6 1 0 0 1 1 1 1 PDZ domain MMR_HSR1 PF01926.23 EGB05704.1 - 3.4e-05 23.9 0.2 0.00033 20.7 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase PDZ_2 PF13180.6 EGB05704.1 - 3.6e-05 24.0 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain GED PF02212.18 EGB05704.1 - 6.8e-05 22.9 0.3 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain FeoB_N PF02421.18 EGB05704.1 - 0.034 13.7 0.0 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B WW PF00397.26 EGB05705.1 - 3.8e-13 49.3 0.2 6.2e-13 48.6 0.2 1.4 1 0 0 1 1 1 1 WW domain CCDC50_N PF15295.6 EGB05705.1 - 0.0013 18.9 0.5 0.0019 18.3 0.5 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus DUF5635 PF18685.1 EGB05705.1 - 0.17 11.8 1.3 2 8.4 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5635) AMP-binding PF00501.28 EGB05706.1 - 3.2e-32 111.7 0.0 4.1e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB05706.1 - 5.3e-09 36.9 0.0 3.2e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGB05706.1 - 8.9e-05 22.3 0.1 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus HGTP_anticodon PF03129.20 EGB05708.1 - 2.6e-22 78.8 0.0 3.2e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain DUF3376 PF11856.8 EGB05708.1 - 0.2 10.6 0.0 0.21 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Abhydrolase_2 PF02230.16 EGB05709.1 - 1.7e-42 145.7 0.0 2.3e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EGB05709.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EGB05709.1 - 2e-05 25.3 0.3 3.3e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGB05709.1 - 0.00013 21.9 0.1 0.00024 21.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB05709.1 - 0.0068 15.9 0.1 3.7 7.0 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGB05709.1 - 0.011 15.1 0.2 0.15 11.3 0.1 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EGB05709.1 - 0.052 13.0 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 EGB05709.1 - 0.083 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 EGB05709.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 EGB05709.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 Putative esterase PH PF00169.29 EGB05709.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 PH domain Lipase_3 PF01764.25 EGB05709.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) AAA PF00004.29 EGB05710.1 - 1.3e-36 125.9 0.0 1.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGB05710.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGB05710.1 - 8.1e-05 22.6 0.0 0.00029 20.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB05710.1 - 0.00013 22.4 0.2 0.00046 20.6 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EGB05710.1 - 0.0014 18.8 0.0 0.0045 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 EGB05710.1 - 0.0031 17.5 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGB05710.1 - 0.0033 17.7 0.1 0.4 10.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGB05710.1 - 0.004 16.5 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGB05710.1 - 0.007 16.0 0.6 0.2 11.2 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB05710.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGB05710.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGB05710.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EGB05710.1 - 0.047 12.9 0.0 0.11 11.6 0.0 1.6 1 1 1 2 2 2 0 TIP49 P-loop domain NACHT PF05729.12 EGB05710.1 - 0.063 13.2 0.0 0.59 10.0 0.0 2.0 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EGB05710.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 EGB05710.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EGB05710.1 - 0.15 12.1 0.0 0.61 10.2 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 EGB05710.1 - 0.16 12.1 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family PXA PF02194.15 EGB05711.1 - 2.2e-14 53.9 0.0 4.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 PXA domain PX PF00787.24 EGB05711.1 - 1.5e-11 44.2 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 PX domain Nexin_C PF08628.12 EGB05711.1 - 5.9e-06 26.8 0.1 2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Sorting nexin C terminal RUN PF02759.19 EGB05711.1 - 0.18 11.7 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 RUN domain IQ PF00612.27 EGB05712.1 - 6.1 6.9 5.6 2.9 7.9 2.0 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif NAC PF01849.18 EGB05713.1 - 2.3e-22 78.7 0.1 4.4e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 NAC domain Peptidase_M24 PF00557.24 EGB05714.1 - 8.2e-25 87.7 0.0 1.1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TPR_1 PF00515.28 EGB05715.1 - 4.4e-08 32.6 3.0 0.61 10.0 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05715.1 - 2.8e-06 27.0 13.7 1.2 9.4 0.6 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB05715.1 - 0.0012 19.1 18.5 0.3 11.4 0.2 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB05715.1 - 0.0022 18.1 17.1 1.1 9.4 0.1 7.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05715.1 - 0.0048 17.0 1.3 0.6 10.5 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05715.1 - 0.013 15.8 6.2 2.2e+02 2.6 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05715.1 - 0.31 11.7 33.4 0.33 11.6 0.2 8.0 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05715.1 - 2.2 9.1 9.1 68 4.4 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05715.1 - 7 6.9 6.4 1.8 8.8 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PRiA4_ORF3 PF07929.11 EGB05716.1 - 0.059 13.1 0.5 0.083 12.6 0.5 1.3 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein DBR1 PF05011.13 EGB05716.1 - 0.12 12.8 1.6 0.21 12.0 1.6 1.4 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain ATPgrasp_Ter PF15632.6 EGB05716.1 - 0.14 11.9 0.5 0.38 10.5 0.0 1.9 2 1 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Acyl-CoA_ox_N PF14749.6 EGB05716.1 - 0.15 12.6 3.3 0.28 11.7 3.3 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal CotJB PF12652.7 EGB05716.1 - 0.16 12.2 0.7 0.37 11.0 0.7 1.6 1 0 0 1 1 1 0 CotJB protein ParB PF08775.10 EGB05716.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 ParB family Ureide_permease PF07168.11 EGB05718.1 - 0.71 8.6 3.7 0.86 8.3 3.7 1.0 1 0 0 1 1 1 0 Ureide permease PHD PF00628.29 EGB05719.1 - 0.00098 19.0 11.7 0.0036 17.2 11.7 2.1 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 EGB05719.1 - 0.066 13.3 10.0 0.27 11.3 10.0 2.1 1 1 0 1 1 1 0 PHD-finger Chordopox_A30L PF06015.12 EGB05719.1 - 0.2 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Chloroa_b-bind PF00504.21 EGB05720.1 - 1.1e-27 97.5 0.0 1.5e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Coatomer_WDAD PF04053.14 EGB05721.1 - 1.1e-115 387.3 0.0 1.6e-115 386.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EGB05721.1 - 2.6e-101 339.3 0.0 3.6e-101 338.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EGB05721.1 - 4.5e-43 144.4 19.7 2.1e-09 37.8 0.3 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05721.1 - 8e-11 42.1 1.1 0.00014 22.1 0.1 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGB05721.1 - 0.14 10.9 1.0 1.4 7.6 0.0 3.0 3 1 1 4 4 4 0 Nup133 N terminal like Nup160 PF11715.8 EGB05721.1 - 3.5 6.2 8.5 2.9 6.4 0.2 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Cyclin PF08613.11 EGB05722.1 - 8.8e-36 123.7 0.2 1e-35 123.5 0.2 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGB05722.1 - 5.6e-09 35.8 0.1 7e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Plus-3 PF03126.18 EGB05723.1 - 3.7e-29 101.4 0.0 2.8e-28 98.6 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain DUF3734 PF12536.8 EGB05723.1 - 0.31 11.4 6.1 0.12 12.7 2.4 2.2 2 1 0 2 2 2 0 Patatin phospholipase HABP4_PAI-RBP1 PF04774.15 EGB05723.1 - 1.8 9.4 5.7 2.2 9.2 2.4 2.8 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family DOT1 PF08123.13 EGB05725.1 - 1.4e-11 44.4 0.3 1.6e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Histone methylation protein DOT1 CC2D2AN-C2 PF15625.6 EGB05726.1 - 1.3e-18 67.4 0.4 8.3e-18 64.7 0.1 2.5 3 0 0 3 3 3 1 CC2D2A N-terminal C2 domain ENTH PF01417.20 EGB05727.1 - 1.2e-35 122.3 0.0 1.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGB05727.1 - 0.0061 15.6 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DpnI_C PF17726.1 EGB05727.1 - 0.057 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Dam-replacing HTH domain XOO_2897-deam PF14440.6 EGB05727.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Pyrophosphatase PF00719.19 EGB05728.1 - 4.4e-45 153.3 0.1 5.7e-45 153.0 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase B9-C2 PF07162.11 EGB05729.1 - 5.4e-46 156.9 0.0 6.6e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Coatomer_WDAD PF04053.14 EGB05730.1 - 5.8e-137 457.4 0.0 8.8e-137 456.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EGB05730.1 - 8.5e-30 102.4 2.3 8.1e-08 32.8 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05730.1 - 0.00049 20.3 0.2 2.8 8.3 0.0 5.1 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain ARL2_Bind_BART PF11527.8 EGB05731.1 - 4.8e-31 107.3 1.7 4.8e-31 107.3 1.7 2.4 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART BTB_2 PF02214.22 EGB05731.1 - 3.4e-15 56.1 0.0 7.3e-14 51.9 0.0 2.9 2 0 0 2 2 2 1 BTB/POZ domain RPN1_RPN2_N PF17781.1 EGB05732.1 - 1.2e-109 366.5 0.0 1.7e-109 366.0 0.0 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGB05732.1 - 7.4e-25 86.7 0.1 1.4e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGB05732.1 - 1.2e-19 69.7 9.4 0.00036 20.8 0.3 7.1 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGB05732.1 - 1.7e-07 31.6 1.9 0.00043 20.6 0.0 3.6 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EGB05732.1 - 0.12 12.9 0.5 25 5.5 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 EGB05732.1 - 0.35 11.2 1.3 32 5.1 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Pkinase PF00069.25 EGB05735.1 - 2.6e-68 230.3 0.0 3e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05735.1 - 9.2e-37 126.7 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05735.1 - 9.8e-06 25.1 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGB05735.1 - 0.00025 20.1 0.6 0.00035 19.6 0.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain CENP-B_N PF04218.13 EGB05735.1 - 0.25 11.0 0.9 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain cNMP_binding PF00027.29 EGB05736.1 - 9.9e-58 192.2 1.5 3.1e-22 78.5 0.0 4.9 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGB05736.1 - 6.1e-52 176.6 0.0 1.4e-51 175.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05736.1 - 7.5e-27 94.2 0.0 1.4e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05736.1 - 0.00075 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB05736.1 - 0.15 12.0 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Coatomer_b_Cpla PF14806.6 EGB05737.1 - 1.7e-56 189.7 0.0 3.8e-56 188.5 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EGB05737.1 - 1.8e-51 173.7 0.0 3.1e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Coatomer beta C-terminal region Adaptin_N PF01602.20 EGB05737.1 - 1.7e-44 152.3 0.1 2.4e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_g_Cpla PF16381.5 EGB05737.1 - 0.00077 19.6 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform DUF484 PF04340.12 EGB05737.1 - 0.0066 16.2 0.3 0.021 14.5 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF484 HEAT_2 PF13646.6 EGB05737.1 - 0.025 15.0 1.5 3.3 8.2 0.1 2.5 1 1 1 2 2 2 0 HEAT repeats Arm PF00514.23 EGB05737.1 - 0.14 12.2 1.4 0.71 10.0 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Alpha_adaptinC2 PF02883.20 EGB05737.1 - 0.16 12.3 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Adaptin C-terminal domain Ins_P5_2-kin PF06090.12 EGB05738.1 - 1.4e-11 44.5 0.0 1.8e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Vac14_Fab1_bd PF12755.7 EGB05739.1 - 2e-44 150.1 0.0 9.5e-42 141.5 0.0 2.3 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGB05739.1 - 9.1e-14 50.4 0.6 2.5e-05 24.1 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 EGB05739.1 - 3.6e-08 33.6 0.0 0.00058 19.9 0.0 3.1 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGB05739.1 - 1.5e-07 31.8 0.1 0.0018 18.7 0.0 3.7 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 EGB05739.1 - 5.6e-07 29.9 0.0 0.37 11.2 0.0 4.3 1 1 0 2 2 2 2 HEAT repeats Tti2 PF10521.9 EGB05739.1 - 0.0023 17.5 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 Tti2 family MMS19_C PF12460.8 EGB05739.1 - 0.16 11.1 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Pkinase PF00069.25 EGB05740.1 - 3.3e-58 197.1 0.1 4.9e-58 196.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05740.1 - 1.7e-27 96.3 0.6 1.2e-25 90.3 0.6 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB05740.1 - 0.0004 19.8 0.1 0.001 18.5 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC4_D PF16856.5 EGB05740.1 - 0.019 14.8 0.6 0.052 13.4 0.1 1.9 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain APH PF01636.23 EGB05740.1 - 0.058 13.3 0.1 0.24 11.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC2_membrane PF01061.24 EGB05741.1 - 0.056 12.9 2.8 0.073 12.5 2.8 1.1 1 0 0 1 1 1 0 ABC-2 type transporter WD40 PF00400.32 EGB05742.1 - 9.1e-14 51.6 3.9 0.00058 20.6 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05742.1 - 1.3e-08 35.0 0.1 1.4 9.3 0.0 5.2 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3334 PF11813.8 EGB05742.1 - 0.097 12.4 2.2 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) Filamin PF00630.19 EGB05743.1 - 3.8e-43 146.5 0.0 9.2e-11 42.5 0.0 8.1 8 0 0 8 8 8 6 Filamin/ABP280 repeat PA14 PF07691.12 EGB05743.1 - 6.9e-14 51.9 0.0 7.7e-07 29.0 0.0 3.1 3 0 0 3 3 3 2 PA14 domain Invasin_D3 PF09134.10 EGB05743.1 - 3.4e-09 36.9 11.2 0.47 10.8 0.0 7.2 7 0 0 7 7 7 4 Invasin, domain 3 Calx-beta PF03160.14 EGB05743.1 - 0.0016 18.5 0.0 0.0053 16.9 0.0 1.9 1 0 0 1 1 1 1 Calx-beta domain Neurexophilin PF06312.12 EGB05743.1 - 0.023 14.1 0.0 0.37 10.2 0.0 2.6 2 0 0 2 2 2 0 Neurexophilin Peptidase_M14 PF00246.24 EGB05744.1 - 2.5e-15 57.0 0.0 9.9e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EGB05744.1 - 9.9e-08 32.3 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EGB05744.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Glyco_transf_8 PF01501.20 EGB05745.1 - 2.4e-06 27.3 0.0 1.1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGB05745.1 - 0.0038 16.6 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Pkinase PF00069.25 EGB05746.1 - 1.3e-52 178.8 0.0 1.6e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05746.1 - 2.6e-37 128.5 0.0 3.4e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05746.1 - 0.0028 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TIP41 PF04176.13 EGB05747.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 TIP41-like family JAB PF01398.21 EGB05748.1 - 1.3e-07 31.6 0.0 3.7e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPR_2 PF07719.17 EGB05749.1 - 3.5e-07 29.8 0.1 6.6e-05 22.7 0.7 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05749.1 - 0.015 15.1 0.7 0.037 13.8 0.5 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05749.1 - 0.099 12.3 0.1 0.79 9.5 0.2 2.2 1 1 1 2 2 2 0 TPR repeat Ribosomal_L5_C PF00673.21 EGB05750.1 - 1.1e-21 76.7 0.1 1.8e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGB05750.1 - 3.6e-19 68.9 0.0 1.7e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EGB05750.1 - 0.11 12.2 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain MCM PF00493.23 EGB05751.1 - 6.6e-102 339.3 0.0 1.1e-101 338.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGB05751.1 - 7.4e-31 106.6 1.4 1.2e-30 105.9 1.4 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 EGB05751.1 - 1.1e-12 48.5 0.3 2.3e-12 47.4 0.3 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGB05751.1 - 5.7e-07 29.1 0.1 3.7e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB05751.1 - 8.7e-06 25.8 0.0 3.9e-05 23.7 0.0 2.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB05751.1 - 4.6e-05 23.3 0.1 0.00015 21.6 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGB05751.1 - 0.029 14.8 0.1 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGB05751.1 - 0.079 12.7 0.0 0.49 10.1 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 EGB05751.1 - 0.11 12.9 3.7 1.9 8.8 0.1 3.3 2 2 0 3 3 3 0 AAA ATPase domain B56 PF01603.20 EGB05752.1 - 4.5e-158 526.6 12.1 4.9e-131 437.5 2.2 2.0 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) tRNA-synt_1b PF00579.25 EGB05754.1 - 5.3e-82 275.4 0.0 6.5e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Transmemb_17 PF09799.9 EGB05755.1 - 2.4e-16 60.2 3.9 2.4e-16 60.2 3.9 1.4 1 1 1 2 2 2 1 Predicted membrane protein DAD PF02109.16 EGB05755.1 - 0.027 14.8 0.5 0.044 14.1 0.5 1.3 1 0 0 1 1 1 0 DAD family HMGL-like PF00682.19 EGB05756.1 - 1.1e-86 290.7 0.0 1.5e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EGB05756.1 - 2.6e-30 105.0 0.7 5.3e-30 104.0 0.7 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain RhoGEF PF00621.20 EGB05759.1 - 3.6e-19 69.7 0.0 5.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain cNMP_binding PF00027.29 EGB05760.1 - 1.1e-27 95.9 0.0 1.8e-18 66.4 0.0 2.5 1 1 1 2 2 2 2 Cyclic nucleotide-binding domain PI3_PI4_kinase PF00454.27 EGB05761.1 - 1.7e-52 178.7 0.0 2.4e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EGB05761.1 - 1e-19 70.7 0.3 1.7e-19 70.0 0.3 1.4 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 EGB05761.1 - 1.4e-13 50.4 0.8 3.5e-13 49.1 0.3 2.0 2 0 0 2 2 2 1 FATC domain EF-hand_7 PF13499.6 EGB05762.1 - 8.6e-10 38.9 3.0 1.9e-09 37.8 3.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB05762.1 - 2.6e-09 36.0 7.7 0.00016 20.9 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB05762.1 - 5.4e-07 29.4 5.3 9.2e-07 28.6 1.7 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB05762.1 - 6.5e-07 28.8 6.5 0.00034 20.3 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB05762.1 - 0.012 15.1 9.4 0.57 9.8 0.5 2.6 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 EGB05762.1 - 0.025 14.9 0.2 0.099 13.0 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain Mlo PF03094.15 EGB05762.1 - 0.036 12.4 4.2 0.03 12.7 0.7 2.1 2 0 0 2 2 2 0 Mlo family NLE PF08154.12 EGB05763.1 - 0.16 12.5 0.0 1.7 9.2 0.0 2.3 2 0 0 2 2 2 0 NLE (NUC135) domain CD36 PF01130.21 EGB05764.1 - 8.4e-34 116.9 0.4 7.5e-16 57.7 0.0 3.3 3 0 0 3 3 3 3 CD36 family DUF3638 PF12340.8 EGB05765.1 - 1e-18 67.5 0.0 2.3e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGB05765.1 - 4.9e-14 51.4 0.1 1.3e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) SH3_9 PF14604.6 EGB05765.1 - 1.9e-11 43.6 0.0 4.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB05765.1 - 4.3e-11 42.2 0.0 1.1e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGB05765.1 - 1.8e-09 37.1 0.0 3.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_1 PF00036.32 EGB05765.1 - 1.8e-06 27.1 0.8 0.0042 16.5 0.0 3.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EGB05765.1 - 2.3e-06 28.0 0.9 5.5e-05 23.5 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB05765.1 - 1.2e-05 24.8 5.0 0.16 12.0 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EGB05765.1 - 5.5e-05 22.9 0.0 0.0026 17.6 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB05765.1 - 0.014 14.9 0.1 2.4 7.8 0.0 2.8 2 0 0 2 2 2 0 EF hand Tim54 PF11711.8 EGB05765.1 - 0.019 13.8 2.9 0.26 10.0 0.6 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Roughex PF06020.11 EGB05765.1 - 3.9 6.5 8.3 7.2 5.6 8.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein B9-C2 PF07162.11 EGB05766.1 - 4.6e-35 121.3 0.1 5e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF1484 PF07363.11 EGB05767.1 - 0.14 13.2 2.4 0.3 12.1 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1484) Mce4_CUP1 PF11887.8 EGB05767.1 - 0.34 10.3 1.7 0.72 9.2 1.7 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF2951 PF11166.8 EGB05768.1 - 0.012 15.9 3.4 0.012 15.9 3.4 4.9 5 2 1 7 7 7 0 Protein of unknown function (DUF2951) PglZ PF08665.12 EGB05768.1 - 0.3 11.2 0.1 0.3 11.2 0.1 3.1 2 1 1 3 3 3 0 PglZ domain DUF3772 PF12607.8 EGB05768.1 - 0.91 9.3 3.7 15 5.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) Tankyrase_bdg_C PF15327.6 EGB05769.1 - 0.12 12.8 2.5 0.31 11.5 2.5 1.7 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Astro_capsid_p PF12226.8 EGB05769.1 - 8.9 5.4 6.4 14 4.8 6.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FH2 PF02181.23 EGB05770.1 - 2.8e-06 26.7 0.0 0.024 13.8 0.0 2.6 3 0 0 3 3 3 2 Formin Homology 2 Domain Pkinase PF00069.25 EGB05771.1 - 2.7e-76 256.4 0.0 3.1e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05771.1 - 9.1e-35 120.2 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05771.1 - 0.00012 21.6 0.1 0.027 13.8 0.0 2.3 1 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 EGB05771.1 - 0.00076 18.5 0.0 0.013 14.4 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB05771.1 - 0.016 15.1 0.0 0.072 13.0 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGB05771.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PP2C PF00481.21 EGB05772.1 - 1.5e-32 113.2 0.0 2.1e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Methyltrans_SAM PF10672.9 EGB05773.1 - 7.1e-15 54.9 0.0 1.4e-14 54.0 0.0 1.4 1 1 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 EGB05773.1 - 2.3e-05 24.1 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EGB05773.1 - 0.033 13.9 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Prim-Pol PF09250.11 EGB05773.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.4 1 1 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Cauli_VI PF01693.16 EGB05774.1 - 2.5e-19 69.3 3.5 2.8e-19 69.1 3.5 1.0 1 0 0 1 1 1 1 Caulimovirus viroplasmin Metallophos PF00149.28 EGB05775.1 - 2.4e-07 31.5 0.0 3.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB05775.1 - 7.1e-07 29.6 0.1 0.0013 19.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain HCO3_cotransp PF00955.21 EGB05776.1 - 5.1e-95 319.2 13.6 6.3e-56 190.2 0.2 2.3 1 1 1 2 2 2 2 HCO3- transporter family SLATT_1 PF18181.1 EGB05776.1 - 1.4 8.9 5.8 5.4 7.0 5.8 2.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 ABC_tran PF00005.27 EGB05777.1 - 1e-22 81.1 0.0 1.9e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB05777.1 - 0.00042 20.3 0.2 0.00076 19.4 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane PF01061.24 EGB05777.1 - 0.0027 17.1 4.1 0.0027 17.1 4.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter AAA_23 PF13476.6 EGB05777.1 - 0.029 14.9 0.1 0.05 14.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGB05777.1 - 0.04 13.7 0.2 0.086 12.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGB05777.1 - 0.055 13.2 1.5 0.12 12.1 1.5 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGB05777.1 - 0.11 12.4 0.1 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 EGB05777.1 - 0.37 11.2 3.5 0.26 11.7 0.2 2.4 3 0 0 3 3 3 0 AAA ATPase domain CIA30 PF08547.12 EGB05778.1 - 3.2e-11 43.5 0.0 1.4e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Scramblase PF03803.15 EGB05779.1 - 5.9e-15 55.2 0.7 9.8e-14 51.2 0.7 2.2 1 1 0 1 1 1 1 Scramblase RRM_1 PF00076.22 EGB05781.1 - 5.8e-32 109.3 0.0 6.9e-13 48.2 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB05781.1 - 3.4e-06 26.8 0.0 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif CLZ PF16526.5 EGB05781.1 - 0.11 12.9 4.8 5.3 7.5 0.3 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Radical_SAM PF04055.21 EGB05782.1 - 2.3e-11 44.4 0.0 3.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Chalcone_2 PF16035.5 EGB05782.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Chalcone isomerase like TrmO PF01980.16 EGB05783.1 - 1e-35 122.5 0.0 1.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O Ribosomal_S10 PF00338.22 EGB05784.1 - 3.2e-29 101.0 0.1 4.4e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ACT_4 PF13291.6 EGB05784.1 - 0.036 14.7 0.3 0.24 12.0 0.1 2.1 2 0 0 2 2 2 0 ACT domain ATP-synt_C PF00137.21 EGB05785.1 - 2.4e-27 95.1 26.9 1.5e-14 54.1 8.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C zf-C3HC4_3 PF13920.6 EGB05786.1 - 1.8e-14 53.3 12.4 2e-14 53.2 12.4 1.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB05786.1 - 0.00017 21.4 10.6 0.00022 21.0 10.6 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGB05786.1 - 0.00038 20.4 10.4 0.00048 20.0 10.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGB05786.1 - 0.0046 17.3 13.7 0.0069 16.7 13.7 1.3 1 0 0 1 1 1 1 Ring finger domain DUF1644 PF07800.12 EGB05786.1 - 0.29 11.2 10.6 0.58 10.2 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) RabGAP-TBC PF00566.18 EGB05788.1 - 1.1e-13 51.3 0.0 2.4e-12 47.0 0.0 2.2 2 1 0 2 2 2 2 Rab-GTPase-TBC domain ARL2_Bind_BART PF11527.8 EGB05789.1 - 1.4e-06 28.4 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 2 2 The ARF-like 2 binding protein BART Pkinase PF00069.25 EGB05791.1 - 7.1e-50 169.8 0.0 8e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05791.1 - 7.1e-30 104.2 0.0 7.9e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05791.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB05791.1 - 0.002 18.1 1.1 0.0055 16.7 1.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB05791.1 - 0.0055 16.1 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB05791.1 - 0.059 12.1 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPR_1 PF00515.28 EGB05792.1 - 2.4e-33 112.6 8.7 1.4e-08 34.2 1.4 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05792.1 - 7.6e-28 94.4 8.0 1.4e-05 24.8 1.4 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGB05792.1 - 5.9e-23 80.3 1.0 2.3e-06 27.2 0.5 7.4 3 1 6 9 9 9 5 TPR repeat TPR_16 PF13432.6 EGB05792.1 - 6.7e-21 74.7 18.4 7.6e-08 32.9 0.1 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGB05792.1 - 8e-19 67.9 7.2 1.1e-08 35.4 0.2 6.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB05792.1 - 8.8e-19 66.6 15.5 0.003 18.2 0.1 8.5 3 1 5 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05792.1 - 9.6e-17 59.7 0.9 0.047 13.9 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGB05792.1 - 3e-16 59.5 20.3 0.00013 22.2 0.3 6.6 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05792.1 - 6.6e-16 57.5 7.3 0.048 14.1 0.4 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB05792.1 - 1.3e-15 57.3 26.6 4.1e-07 30.1 0.2 4.4 2 1 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGB05792.1 - 6e-10 38.4 6.7 0.27 11.4 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB05792.1 - 1.5e-08 34.6 22.3 0.0005 20.2 1.5 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGB05792.1 - 7.1e-07 28.9 0.5 0.0032 17.1 0.1 3.5 2 1 2 4 4 4 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 EGB05792.1 - 2e-05 24.4 0.5 0.00043 20.0 0.0 3.1 2 1 2 4 4 4 1 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 EGB05792.1 - 2.3e-05 23.8 0.1 0.56 9.4 0.0 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGB05792.1 - 8.6e-05 22.8 2.2 0.002 18.4 0.3 3.7 3 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05792.1 - 0.0001 22.7 4.5 17 6.3 0.0 6.2 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB05792.1 - 0.015 14.7 5.3 0.034 13.5 1.7 2.7 2 1 1 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 EGB05792.1 - 0.022 14.6 17.4 3.3 7.7 0.4 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGB05792.1 - 0.11 12.6 0.8 0.95 9.5 0.0 2.6 2 1 1 3 3 3 0 Putative TPR-like repeat TOM20_plant PF06552.12 EGB05792.1 - 0.19 11.5 0.1 15 5.3 0.0 3.4 2 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.12 EGB05792.1 - 0.4 10.7 7.1 0.23 11.5 1.9 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat cNMP_binding PF00027.29 EGB05793.1 - 2.1e-27 95.0 0.0 6.6e-14 51.7 0.0 3.0 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain GMP_PDE_delta PF05351.11 EGB05794.1 - 1.8e-33 115.8 0.1 2.7e-33 115.2 0.1 1.3 1 1 0 1 1 1 1 GMP-PDE, delta subunit RmlD_sub_bind PF04321.17 EGB05795.1 - 1.7e-12 47.0 0.0 5e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGB05795.1 - 5.3e-07 29.3 0.0 7.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGB05795.1 - 0.00045 19.4 0.0 0.00091 18.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGB05795.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Latrotoxin_C PF15658.6 EGB05795.1 - 0.036 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Latrotoxin C-terminal domain ABC_membrane PF00664.23 EGB05796.1 - 7.2e-17 61.9 0.0 7.9e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region CS PF04969.16 EGB05797.1 - 0.00031 21.7 0.0 0.0015 19.5 0.1 2.1 2 1 0 2 2 2 1 CS domain Mannosyl_trans3 PF11051.8 EGB05798.1 - 0.099 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative LCAT PF02450.15 EGB05800.1 - 1.5e-32 113.2 0.0 1.8e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EGB05800.1 - 4.8e-05 24.1 0.1 7.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGB05800.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 EGB05800.1 - 0.025 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 EGB05800.1 - 0.051 12.9 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 EGB05800.1 - 0.16 11.8 0.4 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase MTP18 PF10558.9 EGB05801.1 - 1.1e-32 113.3 0.1 1.8e-32 112.6 0.1 1.3 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Beta_elim_lyase PF01212.21 EGB05802.1 - 1.6e-77 260.7 1.6 2e-77 260.4 1.6 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGB05802.1 - 3.2e-07 29.8 0.0 5.5e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGB05802.1 - 0.049 12.9 0.0 0.18 11.1 0.1 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family VCBS PF13517.6 EGB05804.1 - 5.3e-88 289.6 185.9 6.6e-09 36.2 9.2 19.8 9 4 11 20 20 20 18 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3197 PF11432.8 EGB05804.1 - 1.2e-12 47.7 3.8 9 6.2 0.0 12.1 6 3 7 14 14 14 3 Protein of unknown function (DUF3197) AbfS_sensor PF18225.1 EGB05804.1 - 1.5e-12 47.3 0.0 15 5.5 0.0 11.8 13 0 0 13 13 13 2 Sensor histidine kinase (AbfS) sensor domain DUF3060 PF11259.8 EGB05804.1 - 0.0023 17.6 5.2 3.6 7.4 0.0 4.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3060) BT1 PF03092.16 EGB05805.1 - 9.4e-19 67.0 7.9 1.4e-10 40.0 0.6 3.1 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 EGB05805.1 - 0.0013 17.8 3.2 0.034 13.1 0.1 2.5 2 1 0 2 2 2 2 PUCC protein SNARE_assoc PF09335.11 EGB05805.1 - 0.032 14.7 0.2 0.032 14.7 0.2 3.6 4 0 0 4 4 4 0 SNARE associated Golgi protein DUF1772 PF08592.11 EGB05805.1 - 1.9 8.8 10.8 4.6 7.6 0.6 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) FAD_binding_7 PF03441.14 EGB05806.1 - 9.7e-30 103.6 0.9 1e-29 103.5 0.9 1.0 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Aldo_ket_red PF00248.21 EGB05807.1 - 1.1e-15 57.7 0.0 6.7e-09 35.3 0.0 2.2 1 1 1 2 2 2 2 Aldo/keto reductase family Glycos_transf_1 PF00534.20 EGB05807.1 - 0.00034 20.2 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_47 PF01532.20 EGB05810.1 - 2.5e-103 346.4 0.0 3e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 EF-hand_7 PF13499.6 EGB05811.1 - 2.1e-82 271.5 4.5 1.3e-09 38.3 0.0 11.4 11 0 0 11 11 11 10 EF-hand domain pair EF-hand_6 PF13405.6 EGB05811.1 - 3.4e-54 176.2 14.6 0.062 13.3 0.1 19.3 18 0 0 18 18 18 16 EF-hand domain EF-hand_1 PF00036.32 EGB05811.1 - 7.7e-53 172.2 26.9 0.0022 17.4 0.1 18.4 18 1 0 18 18 18 16 EF hand EF-hand_5 PF13202.6 EGB05811.1 - 1.2e-50 166.8 28.4 0.017 14.6 0.1 17.7 18 0 0 18 18 18 15 EF hand EF-hand_8 PF13833.6 EGB05811.1 - 4e-41 138.7 21.2 6.8e-05 22.6 0.0 15.2 12 3 3 15 15 15 9 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB05811.1 - 1.8e-14 54.0 4.7 2.2 8.7 0.0 10.4 10 0 0 10 10 10 3 Secreted protein acidic and rich in cysteine Ca binding region WW PF00397.26 EGB05811.1 - 6.1e-14 51.8 12.2 1.5e-08 34.6 0.2 4.3 4 0 0 4 4 4 3 WW domain HSF_DNA-bind PF00447.17 EGB05813.1 - 8.8e-14 51.9 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding PP2C PF00481.21 EGB05814.1 - 2.7e-33 115.7 0.0 3.8e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB05814.1 - 2.3e-07 30.7 0.2 4.4e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB05814.1 - 0.0057 16.6 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Glyco_hydro_30 PF02055.16 EGB05816.1 - 3.2e-56 190.8 0.0 2e-55 188.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain SpoU_methylase PF00588.19 EGB05816.1 - 1.9e-23 83.2 0.0 4e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family Glyco_hydro_30C PF17189.4 EGB05816.1 - 5.1e-07 29.8 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Ricin_B_lectin PF00652.22 EGB05816.1 - 0.0003 21.0 0.0 0.0085 16.3 0.0 2.1 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain SpoU_sub_bind PF08032.12 EGB05816.1 - 0.00057 20.1 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding LANC_like PF05147.13 EGB05817.1 - 3e-48 164.2 0.0 3.7e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Exostosin PF03016.15 EGB05819.1 - 2.2e-22 79.7 0.0 6.1e-22 78.2 0.0 1.7 1 1 0 1 1 1 1 Exostosin family Nucleotid_trans PF03407.16 EGB05820.1 - 1.3e-28 100.5 0.2 1.7e-28 100.0 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Dus PF01207.17 EGB05821.1 - 1.1e-43 149.5 0.0 1.4e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) EF-hand_4 PF12763.7 EGB05822.1 - 2.6e-06 27.3 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EGB05822.1 - 2.7e-06 27.7 0.4 0.0059 17.0 0.0 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB05822.1 - 2.8e-05 23.4 0.0 0.00018 20.8 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB05822.1 - 9.3e-05 22.1 0.1 0.0054 16.6 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EGB05822.1 - 0.045 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 EF hand SQS_PSY PF00494.19 EGB05823.1 - 1.5e-66 224.6 0.0 2.1e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Sulfotransfer_2 PF03567.14 EGB05824.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family PITH PF06201.13 EGB05826.1 - 1.2e-21 77.5 0.0 2.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 PITH domain Cupin_8 PF13621.6 EGB05826.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin-like domain JmjC PF02373.22 EGB05826.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase C2 PF00168.30 EGB05827.1 - 4.9e-22 78.2 0.0 8.6e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain FYVE PF01363.21 EGB05827.1 - 2.9e-13 49.7 9.8 4.9e-13 49.0 9.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGB05827.1 - 0.054 13.7 5.9 0.11 12.7 5.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger CASP_C PF08172.12 EGB05828.1 - 0.034 13.5 3.1 0.021 14.2 0.7 1.8 2 0 0 2 2 2 0 CASP C terminal GAS PF13851.6 EGB05828.1 - 0.36 10.1 5.0 0.66 9.3 5.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cwf_Cwc_15 PF04889.12 EGB05831.1 - 0.28 10.9 7.6 0.46 10.2 7.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DFRP_C PF16543.5 EGB05831.1 - 1.4 9.5 3.4 3 8.4 3.4 1.5 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Nucleotid_trans PF03407.16 EGB05832.1 - 5.6e-24 85.3 0.0 7.9e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Adap_comp_sub PF00928.21 EGB05833.1 - 4.8e-17 62.2 0.0 7.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family NeA_P2 PF12312.8 EGB05833.1 - 0.082 12.3 0.2 0.082 12.3 0.2 1.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein DUF2732 PF10809.8 EGB05833.1 - 0.11 12.4 0.8 0.22 11.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) FHA PF00498.26 EGB05834.1 - 9.5e-07 29.1 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF1640 PF07798.11 EGB05834.1 - 0.0024 18.0 3.7 0.0024 18.0 3.7 11.9 7 4 3 11 11 11 4 Protein of unknown function (DUF1640) Yop-YscD_cpl PF16697.5 EGB05834.1 - 0.0024 18.2 0.2 0.0072 16.6 0.2 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Surfac_D-trimer PF09006.11 EGB05834.1 - 0.093 12.6 2.6 0.44 10.5 0.0 3.7 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation 3-PAP PF12578.8 EGB05834.1 - 1.7 8.4 10.2 0.33 10.7 0.2 4.8 4 0 0 4 4 4 0 Myotubularin-associated protein HlyD_2 PF12700.7 EGB05834.1 - 1.8 7.2 5.3 0.77 8.4 0.0 2.9 4 0 0 4 4 4 0 HlyD family secretion protein Med28 PF11594.8 EGB05835.1 - 0.78 9.8 5.9 1.2 9.2 0.2 4.4 4 0 0 4 4 4 0 Mediator complex subunit 28 CoA_transf_3 PF02515.17 EGB05836.1 - 4e-39 134.8 1.4 2.1e-33 115.9 0.2 3.2 2 1 0 2 2 2 2 CoA-transferase family III eIF3_subunit PF08597.10 EGB05836.1 - 0.00073 19.5 8.9 0.0011 18.9 8.9 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit MPC PF03650.13 EGB05837.1 - 3e-46 156.1 1.6 2.6e-25 88.7 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial pyruvate carriers PCIF1_WW PF12237.8 EGB05839.1 - 2.6e-54 183.4 0.0 3.5e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain RHH_1 PF01402.21 EGB05839.1 - 0.067 13.2 0.4 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family GST_C_6 PF17171.4 EGB05839.1 - 0.11 12.3 0.9 23 4.9 0.1 2.9 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain cNMP_binding PF00027.29 EGB05840.1 - 7.7e-18 64.4 0.0 1.2e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3268 PF11672.8 EGB05840.1 - 0.035 14.4 0.0 5.3 7.4 0.0 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain Late_protein_L1 PF00500.18 EGB05840.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 L1 (late) protein RTC PF01137.21 EGB05841.1 - 5.8e-37 127.0 0.0 6.7e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGB05841.1 - 1.4e-21 76.9 0.0 2.6e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain FSH1 PF03959.13 EGB05842.1 - 1.5e-13 50.9 0.0 2.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) WD40 PF00400.32 EGB05842.1 - 6.3e-08 33.2 3.3 0.13 13.2 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.6 EGB05842.1 - 1.4 9.5 15.4 11 6.7 0.3 5.4 5 0 0 5 5 5 0 PQQ-like domain Glyco_hydro_35 PF01301.19 EGB05843.1 - 2.6e-52 178.4 0.0 3.6e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 zf-TRAF_2 PF15965.5 EGB05843.1 - 0.00012 22.5 2.7 0.18 12.3 0.2 2.5 2 0 0 2 2 2 2 TRAF-like zinc-finger NTP_transf_2 PF01909.23 EGB05843.1 - 0.0018 18.5 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGB05843.1 - 0.022 15.0 0.0 0.066 13.4 0.0 1.9 1 1 0 1 1 1 0 Cid1 family poly A polymerase Polbeta PF18765.1 EGB05843.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-TRAF PF02176.18 EGB05843.1 - 0.97 10.2 3.9 12 6.6 0.5 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger Ion_trans_2 PF07885.16 EGB05844.1 - 3.5e-31 107.0 20.0 2.5e-19 69.0 5.6 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 EGB05844.1 - 7.8e-09 35.1 5.6 5.7e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 EGB05844.1 - 0.0016 18.8 0.6 0.0046 17.4 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB05844.1 - 0.0037 17.1 0.8 0.02 14.8 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain Lig_chan PF00060.26 EGB05844.1 - 0.016 15.0 1.1 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel EF-hand_5 PF13202.6 EGB05844.1 - 0.051 13.1 0.7 0.051 13.1 0.7 2.8 2 1 0 2 2 2 0 EF hand EF-hand_1 PF00036.32 EGB05844.1 - 0.064 12.8 0.4 0.064 12.8 0.4 2.9 3 1 1 4 4 4 0 EF hand Mito_carr PF00153.27 EGB05845.1 - 1.8e-28 98.3 5.1 3.4e-14 52.5 0.0 5.0 3 2 1 4 4 4 4 Mitochondrial carrier protein Hydrolase_4 PF12146.8 EGB05846.1 - 1.9e-05 24.1 0.5 0.093 12.0 0.3 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Ephrin_rec_like PF07699.13 EGB05846.1 - 0.00036 20.2 1.1 0.00036 20.2 1.1 4.0 2 2 2 4 4 4 1 Putative ephrin-receptor like Peptidase_S9 PF00326.21 EGB05846.1 - 0.0075 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGB05846.1 - 0.02 14.5 0.3 0.74 9.4 0.3 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold UPF0093 PF03653.13 EGB05846.1 - 0.089 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) HSP70 PF00012.20 EGB05847.1 - 4.6e-199 662.5 1.5 5.8e-199 662.2 1.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGB05847.1 - 3.3e-06 26.2 0.8 1.7e-05 23.8 0.7 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Beach PF02138.18 EGB05848.1 - 3.2e-36 125.1 0.0 5e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGB05848.1 - 0.0056 17.5 1.0 14 6.8 0.1 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05848.1 - 0.026 14.8 0.0 0.88 9.9 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_24 PF13578.6 EGB05849.1 - 1.5e-08 35.6 0.0 3.6e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C97 PF05903.14 EGB05850.1 - 8.9e-30 103.5 0.0 9.7e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain OTU PF02338.19 EGB05851.1 - 3.3e-07 30.8 0.0 6.7e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease DAGAT PF03982.13 EGB05852.1 - 4.7e-78 262.1 0.0 5.7e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase SAP PF02037.27 EGB05853.1 - 2.7e-06 27.0 1.5 2.7e-06 27.0 1.5 3.9 4 0 0 4 4 3 1 SAP domain DUF2961 PF11175.8 EGB05853.1 - 3.3e-06 27.0 0.0 4.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) AP3D1 PF06375.11 EGB05853.1 - 0.0063 16.8 11.6 0.02 15.1 11.6 1.8 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 BCAS3 PF12490.8 EGB05853.1 - 0.022 14.3 2.2 0.035 13.6 2.2 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Peptidase_S49_N PF08496.10 EGB05853.1 - 0.2 11.7 9.5 0.45 10.6 9.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.8 EGB05853.1 - 1.2 8.0 15.7 1.9 7.3 15.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 D5_N PF08706.11 EGB05853.1 - 2.1 8.6 6.8 16 5.7 0.1 2.9 2 1 0 2 2 2 0 D5 N terminal like DUF3464 PF11947.8 EGB05853.1 - 2.8 7.7 6.4 10 5.9 6.4 2.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 XRCC4 PF06632.12 EGB05853.1 - 3 6.6 9.9 4.9 5.9 9.9 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SR-25 PF10500.9 EGB05853.1 - 3.9 7.0 24.0 0.34 10.5 15.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Connexin PF00029.19 EGB05853.1 - 8.3 6.1 4.5 13 5.4 4.5 1.2 1 0 0 1 1 1 0 Connexin Rieske PF00355.26 EGB05854.1 - 5.4e-15 55.1 0.0 6.1e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EGB05854.1 - 1.1e-07 31.8 0.0 1.2e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain WD40 PF00400.32 EGB05855.1 - 3.8e-36 122.5 17.1 9.3e-05 23.1 0.2 10.7 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB05855.1 - 1.9e-20 73.0 2.9 0.00045 20.4 0.0 6.9 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB05855.1 - 8.1e-08 32.4 0.0 0.1 12.5 0.0 3.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGB05855.1 - 6.9e-06 24.4 0.0 0.17 9.8 0.0 3.2 3 1 0 3 3 3 2 IKI3 family Frtz PF11768.8 EGB05855.1 - 0.00018 20.0 0.0 0.7 8.1 0.0 3.3 2 2 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 EGB05855.1 - 0.0012 17.9 3.9 2.5 7.0 0.1 5.1 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGB05855.1 - 0.0024 17.8 4.3 0.23 11.4 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EGB05855.1 - 0.27 10.0 1.6 19 3.8 0.2 3.1 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region cobW PF02492.19 EGB05856.1 - 3.6e-23 82.1 0.2 3.9e-23 81.9 0.2 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Herpes_ori_bp PF02399.15 EGB05856.1 - 0.029 12.4 0.0 0.038 12.0 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein AAA_29 PF13555.6 EGB05856.1 - 0.11 12.2 0.3 0.2 11.4 0.2 1.5 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EGB05856.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB05856.1 - 0.18 11.3 0.0 0.74 9.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGB05856.1 - 0.18 12.3 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB05856.1 - 0.19 12.1 0.0 0.2 12.0 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EGB05856.1 - 0.19 12.2 0.0 0.25 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.26 EGB05857.1 - 1.7e-53 181.0 0.1 2.2e-53 180.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB05857.1 - 3.7e-14 52.1 0.0 6.1e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature EBP PF05241.12 EGB05858.1 - 1.7e-25 89.5 2.5 1.7e-25 89.5 2.5 2.0 2 0 0 2 2 2 1 Emopamil binding protein CRAL_TRIO PF00650.20 EGB05858.1 - 1.2e-15 57.5 0.0 4.9e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain 7tm_1 PF00001.21 EGB05858.1 - 0.0058 16.0 3.1 0.011 15.1 3.1 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) adh_short_C2 PF13561.6 EGB05859.1 - 3.5e-60 203.5 4.2 5.5e-60 202.8 4.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB05859.1 - 8.8e-53 178.7 0.7 1.5e-52 177.9 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_3 PF01596.17 EGB05859.1 - 2.8e-42 144.3 0.0 4.3e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGB05859.1 - 4.7e-12 46.9 0.3 1.7e-10 41.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain KR PF08659.10 EGB05859.1 - 7.3e-10 39.0 1.4 1.5e-09 38.0 1.4 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EGB05859.1 - 7.2e-05 23.4 0.9 0.067 13.9 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Epimerase PF01370.21 EGB05859.1 - 0.00016 21.2 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cons_hypoth95 PF03602.15 EGB05859.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Shikimate_DH PF01488.20 EGB05859.1 - 0.0055 16.8 0.1 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PCMT PF01135.19 EGB05859.1 - 0.0088 15.8 0.1 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGB05859.1 - 0.013 15.2 0.0 0.032 14.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 EGB05859.1 - 0.077 13.1 0.7 0.18 11.9 0.7 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGB05859.1 - 0.099 12.0 0.1 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EGB05859.1 - 0.15 11.9 0.8 0.3 10.9 0.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPR_9 PF13371.6 EGB05860.1 - 0.00035 20.7 5.1 0.00035 20.7 5.1 8.8 8 1 2 10 10 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGB05860.1 - 0.0057 17.2 1.4 0.0057 17.2 1.4 14.1 13 2 1 14 14 14 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB05860.1 - 0.21 12.1 4.8 9.5 6.9 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Ras PF00071.22 EGB05862.1 - 1.5e-41 141.7 0.0 1.8e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB05862.1 - 1.8e-21 76.5 0.0 2.4e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB05862.1 - 3.2e-08 33.2 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGB05862.1 - 0.0015 18.5 0.0 0.048 13.6 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EGB05862.1 - 0.014 14.9 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 EGB05862.1 - 0.027 13.9 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGB05862.1 - 0.046 13.8 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 EGB05862.1 - 0.19 11.1 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 EGB05862.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PilJ PF13675.6 EGB05863.1 - 0.018 15.1 2.2 0.029 14.4 1.6 1.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term SlyX PF04102.12 EGB05863.1 - 0.26 11.9 1.1 0.82 10.3 0.2 2.1 1 1 1 2 2 2 0 SlyX PRIMA1 PF16101.5 EGB05864.1 - 0.011 15.8 3.3 0.011 15.8 3.3 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Arf PF00025.21 EGB05865.1 - 1.6e-74 249.2 0.1 1.8e-74 249.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGB05865.1 - 7.1e-16 58.5 0.0 9.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGB05865.1 - 3e-13 49.7 0.0 3.4e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGB05865.1 - 4.5e-12 45.8 0.2 1e-07 31.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGB05865.1 - 4.1e-11 42.6 0.0 4.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGB05865.1 - 7.1e-09 35.4 0.0 9.1e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB05865.1 - 1.2e-08 35.0 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB05865.1 - 0.00051 19.6 0.7 0.0037 16.8 0.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 EGB05865.1 - 0.0034 17.9 0.1 0.027 15.0 0.1 1.9 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 EGB05865.1 - 0.077 12.0 0.1 1.6 7.6 0.2 2.5 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGB05865.1 - 0.13 12.8 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhyH PF05721.13 EGB05866.1 - 1.1e-15 58.5 0.1 1.8e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-UBR PF02207.20 EGB05866.1 - 0.0001 22.4 14.8 0.00023 21.3 14.8 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) GFO_IDH_MocA PF01408.22 EGB05867.1 - 9.2e-17 62.0 0.8 1.7e-16 61.1 0.8 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGB05867.1 - 0.046 13.7 0.0 0.21 11.6 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain VCH_CASS14 PF18315.1 EGB05868.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain DEAD PF00270.29 EGB05869.1 - 2.3e-24 86.1 0.0 3.9e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EGB05869.1 - 5.8e-19 68.6 0.1 1.8e-18 67.0 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EGB05869.1 - 3.4e-12 46.7 0.0 1.8e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGB05869.1 - 0.049 13.6 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EGB05869.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Yae1_N PF09811.9 EGB05870.1 - 2.8e-05 23.7 18.6 0.26 11.0 1.8 4.7 1 1 2 3 3 3 3 Essential protein Yae1, N terminal Cyclin_N PF00134.23 EGB05871.1 - 2.5e-12 46.7 0.1 2.4e-10 40.2 0.0 2.3 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EGB05871.1 - 0.0046 17.3 0.0 0.0074 16.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 EGB05871.1 - 0.023 14.7 0.5 1.4 9.0 0.2 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C PF02984.19 EGB05871.1 - 0.079 13.0 0.1 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 Cyclin, C-terminal domain Ank_2 PF12796.7 EGB05872.1 - 8.3e-25 87.2 6.2 1e-07 32.4 0.2 6.2 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB05872.1 - 1.3e-18 67.1 6.2 0.028 15.0 0.0 8.1 6 1 0 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB05872.1 - 8.9e-15 54.6 23.2 0.00056 20.2 0.5 6.9 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB05872.1 - 2.4e-10 39.7 8.6 1.5 9.6 0.1 8.5 9 0 0 9 9 9 4 Ankyrin repeat Lactamase_B PF00753.27 EGB05872.1 - 4.6e-08 33.3 5.6 5.7e-08 33.0 2.5 2.9 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Ank PF00023.30 EGB05872.1 - 0.00081 19.7 27.4 2.2 8.8 0.8 9.2 10 0 0 10 10 10 3 Ankyrin repeat gpW PF02831.15 EGB05873.1 - 2.9 7.8 17.4 7.7 6.5 0.2 5.8 6 0 0 6 6 6 0 gpW Ferredoxin_N PF16947.5 EGB05873.1 - 6.8 6.9 12.7 33 4.7 0.2 4.8 5 0 0 5 5 5 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding Bestrophin PF01062.21 EGB05874.1 - 2.6e-27 96.0 0.3 1.1e-13 51.2 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel PAP_fibrillin PF04755.12 EGB05874.1 - 7e-07 29.4 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 PAP_fibrillin TraW_N PF12477.8 EGB05874.1 - 5 7.2 8.5 0.43 10.6 1.6 3.0 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal TIR_2 PF13676.6 EGB05876.1 - 3e-09 37.5 0.1 5.8e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 TIR domain DUF3429 PF11911.8 EGB05876.1 - 0.011 16.0 2.4 0.018 15.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) PAN_2 PF08276.11 EGB05876.1 - 0.033 14.3 0.5 0.32 11.2 0.1 2.4 2 0 0 2 2 2 0 PAN-like domain FA_desaturase PF00487.24 EGB05876.1 - 0.23 11.3 2.1 0.27 11.1 0.7 1.7 2 0 0 2 2 2 0 Fatty acid desaturase Glycos_transf_4 PF00953.21 EGB05877.1 - 1.4e-30 106.3 10.3 2.3e-30 105.7 10.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 4 DUF5600 PF18150.1 EGB05878.1 - 1.3e-36 125.5 0.0 5.2e-36 123.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 EGB05878.1 - 2.4e-14 53.7 0.0 6e-13 49.2 0.0 2.1 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 EGB05878.1 - 1.4e-09 37.7 0.1 1.4e-09 37.7 0.1 2.0 2 0 0 2 2 2 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 EGB05878.1 - 5.9e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB05878.1 - 0.0015 18.1 0.0 0.0083 15.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EGB05878.1 - 0.0078 16.4 0.0 0.98 9.7 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EGB05878.1 - 0.039 13.5 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 EGB05878.1 - 0.097 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB05878.1 - 0.11 12.9 0.0 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGB05878.1 - 0.13 12.1 0.0 16 5.4 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_2 PF07724.14 EGB05880.1 - 4.1e-44 150.7 0.0 2.9e-41 141.4 0.0 3.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGB05880.1 - 9.6e-31 105.8 0.1 9.6e-31 105.8 0.1 3.4 4 0 0 4 4 2 1 AAA lid domain AAA PF00004.29 EGB05880.1 - 3.5e-24 85.7 0.0 3.1e-11 43.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGB05880.1 - 9.9e-17 61.2 0.0 2.7e-10 40.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 EGB05880.1 - 7.9e-12 45.1 12.6 2.9e-09 36.9 0.3 3.8 4 0 0 4 4 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 EGB05880.1 - 8.7e-11 41.7 0.2 7.2e-10 38.8 0.0 2.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 EGB05880.1 - 6.6e-10 39.4 2.4 0.00037 20.8 0.0 4.3 4 2 0 4 4 2 2 AAA domain Sigma54_activat PF00158.26 EGB05880.1 - 6.6e-10 38.9 0.0 1.1e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 EGB05880.1 - 4e-08 33.8 1.0 6.8e-06 26.6 0.0 5.7 3 3 2 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 EGB05880.1 - 6.5e-08 33.2 0.0 0.021 15.4 0.0 3.7 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EGB05880.1 - 5.3e-07 29.5 0.0 0.018 14.8 0.0 3.0 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 EGB05880.1 - 7.3e-07 28.8 0.0 0.0031 16.9 0.0 3.1 2 1 1 3 3 3 2 Bacterial TniB protein AAA_7 PF12775.7 EGB05880.1 - 8.9e-07 28.6 0.0 0.021 14.3 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region RuvB_N PF05496.12 EGB05880.1 - 4.2e-06 26.6 2.1 0.1 12.3 1.2 3.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGB05880.1 - 4.2e-06 26.8 0.0 0.016 15.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 EGB05880.1 - 5.4e-05 23.0 0.0 0.052 13.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGB05880.1 - 9.5e-05 22.8 0.0 0.78 10.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase_2 PF01637.18 EGB05880.1 - 0.0001 22.3 0.0 0.41 10.5 0.0 3.8 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EGB05880.1 - 0.00028 20.3 1.1 1.9 7.8 0.0 4.1 3 2 0 3 3 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EGB05880.1 - 0.00039 20.5 0.0 1.1 9.2 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGB05880.1 - 0.0022 18.4 0.4 1.4 9.2 0.0 3.8 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 EGB05880.1 - 0.0027 17.0 0.4 0.69 9.2 0.0 3.1 3 0 0 3 3 2 1 Zeta toxin AAA_23 PF13476.6 EGB05880.1 - 0.0027 18.2 0.1 7.8 6.9 0.0 3.4 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGB05880.1 - 0.0067 16.1 0.4 2 8.0 0.0 3.0 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_3 PF07726.11 EGB05880.1 - 0.0098 15.7 0.0 5.3 6.9 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGB05880.1 - 0.012 14.6 0.0 0.045 12.8 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein TsaE PF02367.17 EGB05880.1 - 0.013 15.5 0.0 7.9 6.5 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EGB05880.1 - 0.013 15.4 0.0 3.4 7.6 0.0 2.7 3 0 0 3 3 2 0 RsgA GTPase Rad17 PF03215.15 EGB05880.1 - 0.014 15.3 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 EGB05880.1 - 0.015 15.4 2.4 0.067 13.3 0.0 2.9 4 0 0 4 4 2 0 Helicase HerA, central domain NACHT PF05729.12 EGB05880.1 - 0.016 15.1 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 EGB05880.1 - 0.017 15.3 0.0 9.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EGB05880.1 - 0.02 14.5 0.0 0.02 14.5 0.0 3.7 4 0 0 4 4 3 0 AAA domain TIP49 PF06068.13 EGB05880.1 - 0.021 14.0 0.3 6.5 5.8 0.0 3.0 3 0 0 3 3 3 0 TIP49 P-loop domain DNA_pol3_delta2 PF13177.6 EGB05880.1 - 0.021 14.6 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit ABC_tran PF00005.27 EGB05880.1 - 0.022 15.3 0.0 7.9 7.0 0.0 3.2 3 0 0 3 3 2 0 ABC transporter AAA_28 PF13521.6 EGB05880.1 - 0.026 14.7 11.3 0.35 11.1 0.0 4.6 5 1 1 6 6 2 0 AAA domain AAA_29 PF13555.6 EGB05880.1 - 0.03 14.1 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_6 PF12774.7 EGB05880.1 - 0.038 12.9 0.0 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EGB05880.1 - 0.059 13.5 13.9 0.82 9.8 0.0 4.7 5 1 0 5 5 2 0 AAA domain NTPase_1 PF03266.15 EGB05880.1 - 0.079 12.9 0.1 5.9 6.8 0.0 3.0 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.6 EGB05880.1 - 0.12 12.1 3.7 5.8 6.6 0.0 3.6 4 0 0 4 4 3 0 AAA domain zf-C4H2 PF10146.9 EGB05880.1 - 0.13 12.6 1.0 0.25 11.6 0.2 1.9 2 0 0 2 2 1 0 Zinc finger-containing protein MerR-DNA-bind PF09278.11 EGB05880.1 - 0.28 11.7 6.1 4.9 7.8 0.0 4.4 4 0 0 4 4 3 0 MerR, DNA binding AAA_17 PF13207.6 EGB05880.1 - 0.43 11.0 3.3 33 4.9 0.0 3.7 4 1 0 4 4 3 0 AAA domain CorA PF01544.18 EGB05880.1 - 2 7.7 3.9 2.2 7.5 1.5 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4355 PF14265.6 EGB05880.1 - 8.6 6.6 8.7 61 3.9 8.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) Mannosyl_trans PF05007.13 EGB05881.1 - 2.8e-36 125.7 0.0 1.5e-35 123.3 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGB05881.1 - 6.1e-06 25.5 0.0 9.6e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2079 PF09852.9 EGB05881.1 - 7.5 5.3 12.2 0.37 9.6 4.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) SNF PF00209.18 EGB05882.1 - 1.5e-92 311.0 4.7 5.2e-45 154.1 6.7 3.0 1 1 2 3 3 3 3 Sodium:neurotransmitter symporter family adh_short PF00106.25 EGB05883.1 - 2.9e-28 98.7 6.3 8.1e-26 90.7 2.6 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGB05883.1 - 9.5e-19 67.9 6.7 2.5e-15 56.7 2.9 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB05883.1 - 1.5e-09 38.0 0.8 2.4e-09 37.4 0.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB05883.1 - 1.9e-05 24.3 1.2 4.4e-05 23.1 1.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB05883.1 - 0.0028 17.5 5.4 0.0042 17.0 5.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGB05883.1 - 0.092 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AAA PF00004.29 EGB05884.1 - 1.7e-13 51.2 0.0 2.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGB05884.1 - 1.3e-05 24.7 0.1 0.0018 17.7 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGB05884.1 - 3.8e-05 23.9 0.0 5.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGB05884.1 - 0.0011 19.2 0.0 0.49 10.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 EGB05884.1 - 0.0025 17.6 0.0 0.0067 16.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EGB05884.1 - 0.0029 17.3 0.5 0.0054 16.5 0.5 1.5 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGB05884.1 - 0.0036 17.0 0.0 0.15 11.7 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGB05884.1 - 0.0053 17.2 0.3 0.025 15.0 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EGB05884.1 - 0.0057 17.0 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB05884.1 - 0.015 15.5 0.1 0.03 14.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGB05884.1 - 0.018 14.2 0.2 1.4 8.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGB05884.1 - 0.027 14.9 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EGB05884.1 - 0.04 14.5 0.0 0.083 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGB05884.1 - 0.042 13.8 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EGB05884.1 - 0.056 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF374 PF04028.13 EGB05884.1 - 0.063 12.8 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Viral_helicase1 PF01443.18 EGB05884.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cNMP_binding PF00027.29 EGB05885.1 - 1.1e-20 73.5 0.0 2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 EGB05885.1 - 0.034 13.9 0.4 0.066 12.9 0.4 1.4 1 0 0 1 1 1 0 Cupin domain Methyltransf_4 PF02390.17 EGB05886.1 - 6.8e-40 136.3 0.0 8.5e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGB05886.1 - 0.00062 20.4 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RsmJ PF04378.13 EGB05886.1 - 0.0025 17.1 0.0 0.0055 16.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Methyltransf_31 PF13847.6 EGB05886.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB05886.1 - 0.18 12.6 0.0 1.4 9.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Myosin_head PF00063.21 EGB05887.1 - 4.4e-33 114.5 0.0 4.6e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB05887.1 - 0.0016 18.9 0.0 0.0026 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGB05887.1 - 0.013 15.8 0.2 0.023 14.9 0.1 1.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGB05887.1 - 0.025 14.6 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGB05887.1 - 0.031 13.5 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 EGB05887.1 - 0.037 13.1 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF600 PF04634.12 EGB05887.1 - 0.053 13.6 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF600 AAA_6 PF12774.7 EGB05887.1 - 0.062 12.3 0.1 0.081 11.9 0.1 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DNA_pol3_delta2 PF13177.6 EGB05887.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_7 PF12775.7 EGB05887.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EGB05887.1 - 0.16 12.3 0.1 0.24 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 EGB05888.1 - 4.7e-92 309.3 0.0 5.5e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Palm_thioest PF02089.15 EGB05889.1 - 3e-54 184.4 0.0 3.5e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGB05889.1 - 0.00055 19.5 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) zf-MYND PF01753.18 EGB05890.1 - 1.1e-08 35.0 29.2 7.1e-06 26.0 16.3 2.5 2 0 0 2 2 2 2 MYND finger zf-CCCH PF00642.24 EGB05891.1 - 1.3e-05 25.0 0.2 2.3e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGB05891.1 - 0.00011 22.1 3.3 0.00023 21.1 3.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGB05891.1 - 0.00093 18.9 0.4 0.00093 18.9 0.4 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger Methyltransf_32 PF13679.6 EGB05891.1 - 0.091 12.7 0.1 0.44 10.5 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain zf-CCCH_2 PF14608.6 EGB05891.1 - 0.22 12.0 0.5 0.47 11.0 0.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Kelch_6 PF13964.6 EGB05892.1 - 2e-08 34.2 0.1 0.00017 21.8 0.0 4.8 3 1 1 4 4 4 1 Kelch motif MFS_1 PF07690.16 EGB05892.1 - 2.5e-07 30.0 52.2 5.2e-07 28.9 52.2 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Kelch_3 PF13415.6 EGB05892.1 - 3.5e-07 30.4 2.4 0.0022 18.2 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 EGB05892.1 - 1.1e-06 28.6 0.2 0.006 16.6 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EGB05892.1 - 1.8e-06 27.4 8.9 0.00036 20.1 0.0 4.4 5 1 0 5 5 5 2 Kelch motif F-box PF00646.33 EGB05892.1 - 3.8e-05 23.4 0.6 8.1e-05 22.4 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGB05892.1 - 0.00012 21.9 0.3 0.00028 20.7 0.3 1.6 1 0 0 1 1 1 1 F-box-like Kelch_2 PF07646.15 EGB05892.1 - 0.0013 18.7 0.1 0.73 9.9 0.0 3.3 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 EGB05892.1 - 0.13 12.3 1.4 0.4 10.7 0.2 2.5 2 0 0 2 2 2 0 Kelch motif Rhomboid PF01694.22 EGB05893.1 - 1.7e-17 63.8 0.2 1.9e-17 63.6 0.2 1.1 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 EGB05893.1 - 0.01 15.8 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 0 Der1-like family DUF1751 PF08551.10 EGB05893.1 - 0.012 16.1 0.0 0.014 16.0 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) NAD_binding_1 PF00175.21 EGB05894.1 - 2.3e-13 50.7 0.0 3.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Peptidase_C16 PF01831.17 EGB05894.1 - 0.0056 16.4 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C16 family BSP_II PF05432.11 EGB05895.1 - 0.053 13.2 8.2 0.11 12.2 8.2 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.12 EGB05895.1 - 0.28 10.5 10.4 0.5 9.6 10.4 1.3 1 0 0 1 1 1 0 NOA36 protein Spem1 PF15670.5 EGB05895.1 - 0.46 10.0 0.9 0.72 9.4 0.9 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Cwf_Cwc_15 PF04889.12 EGB05895.1 - 1.3 8.7 11.2 2 8.1 11.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 EGB05895.1 - 1.3 8.1 4.2 2.2 7.4 4.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.11 EGB05895.1 - 1.3 9.0 7.2 2.3 8.2 7.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 EGB05895.1 - 1.6 6.9 8.7 2.2 6.4 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 EGB05895.1 - 1.8 8.2 6.9 3.2 7.4 6.9 1.3 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.11 EGB05895.1 - 2.5 6.9 6.6 3.4 6.4 6.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sigma70_ner PF04546.13 EGB05895.1 - 2.5 7.9 6.4 4.8 7.0 6.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EGB05895.1 - 2.6 6.3 6.8 4.4 5.5 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EGB05895.1 - 4 5.4 12.4 5.7 4.9 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Afi1 PF07792.12 EGB05895.1 - 7 7.1 6.4 59 4.1 7.9 1.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sporozoite_P67 PF05642.11 EGB05895.1 - 8.9 4.3 6.7 14 3.6 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_S9_N PF02897.15 EGB05896.1 - 3.2e-65 220.6 0.0 5.4e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGB05896.1 - 7.2e-52 175.9 0.0 1.1e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EGB05896.1 - 0.016 15.1 1.0 5.9 7.0 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 EGB05896.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AMP-binding PF00501.28 EGB05897.1 - 6.2e-61 206.3 0.0 6.9e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Sacchrp_dh_NADP PF03435.18 EGB05898.1 - 2.5e-14 53.6 0.5 4.4e-14 52.9 0.5 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGB05898.1 - 0.00036 20.5 2.4 0.00036 20.5 2.4 1.7 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EGB05898.1 - 0.013 15.1 0.2 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Methyltransf_25 PF13649.6 EGB05899.1 - 6.2e-14 52.5 0.1 1.8e-13 51.0 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05899.1 - 4.1e-11 42.9 0.0 7.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB05899.1 - 5e-11 43.1 0.0 1.5e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB05899.1 - 3.1e-10 40.1 0.0 6.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB05899.1 - 3.1e-09 37.5 0.0 6.9e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF4213 PF13938.6 EGB05899.1 - 0.042 14.1 0.4 0.56 10.5 0.0 2.5 2 0 0 2 2 2 0 Putative heavy-metal chelation TIMELESS_C PF05029.13 EGB05900.1 - 0.027 13.6 1.2 0.053 12.7 1.2 1.4 1 0 0 1 1 1 0 Timeless protein C terminal region DLH PF01738.18 EGB05901.1 - 6.8e-23 81.4 0.1 1.2e-22 80.6 0.1 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGB05901.1 - 1.4e-08 34.5 0.0 4.3e-05 23.1 0.1 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family FKBP_C PF00254.28 EGB05901.1 - 5.3e-06 26.7 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PAZ PF02170.22 EGB05901.1 - 9.6e-05 22.2 0.0 0.00026 20.8 0.0 1.6 2 0 0 2 2 2 1 PAZ domain Abhydrolase_3 PF07859.13 EGB05901.1 - 0.0076 16.1 0.9 0.11 12.3 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EGB05901.1 - 0.01 15.5 0.0 0.031 13.9 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Pyrophosphatase PF00719.19 EGB05902.1 - 1.2e-45 155.2 0.0 1.6e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase RCC1 PF00415.18 EGB05904.1 - 5.6e-18 65.3 12.5 6.1e-12 46.0 0.1 3.8 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB05904.1 - 4.2e-16 58.3 15.1 4.2e-07 29.6 1.6 3.2 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat zf-C3HC4_3 PF13920.6 EGB05905.1 - 1.7e-14 53.4 6.1 2.1e-14 53.1 6.1 1.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB05905.1 - 8e-09 35.2 8.1 9.4e-09 35.0 8.1 1.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGB05905.1 - 8.3e-07 28.8 7.1 1.1e-06 28.4 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB05905.1 - 1.1e-05 25.7 9.2 1.4e-05 25.4 9.2 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB05905.1 - 1.5e-05 24.8 9.2 1.8e-05 24.5 9.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB05905.1 - 0.00056 19.8 9.5 0.00072 19.5 9.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB05905.1 - 0.017 15.1 5.4 0.18 11.9 6.0 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 EGB05905.1 - 0.12 12.1 9.9 0.46 10.3 9.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain dNK PF01712.19 EGB05907.1 - 1.2e-15 57.9 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase Herpes_TK PF00693.18 EGB05907.1 - 0.0001 21.7 0.0 0.35 10.0 0.1 2.1 1 1 0 2 2 2 2 Thymidine kinase from herpesvirus Thymidylate_kin PF02223.17 EGB05907.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_18 PF13238.6 EGB05907.1 - 0.04 14.5 0.0 0.1 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Caskin-Pro-rich PF16907.5 EGB05907.1 - 0.067 13.7 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Proline rich region of Caskin proteins AAA_28 PF13521.6 EGB05907.1 - 0.072 13.3 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF3335 PF11814.8 EGB05908.1 - 0.025 14.1 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family SpoIIE PF07228.12 EGB05909.1 - 0.001 19.1 6.4 0.12 12.3 6.4 3.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGB05909.1 - 0.012 15.3 0.3 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein phosphatase 2C FTCD_C PF04961.12 EGB05909.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.0 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase RCC1 PF00415.18 EGB05910.1 - 5.3e-48 161.4 27.7 1.5e-12 47.9 1.1 9.2 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB05910.1 - 1.9e-30 104.0 41.5 9.6e-07 28.5 0.6 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat EamA PF00892.20 EGB05910.1 - 6.4e-13 49.0 27.1 2.1e-10 40.9 9.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family DUF616 PF04765.13 EGB05910.1 - 3.9e-08 32.9 0.0 2.7e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF616) SLC35F PF06027.12 EGB05910.1 - 1e-06 28.5 2.5 1.8e-06 27.7 2.5 1.3 1 0 0 1 1 1 1 Solute carrier family 35 GST_C_3 PF14497.6 EGB05910.1 - 3.1e-06 27.3 0.0 6.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB05910.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AAA_lid_2 PF17863.1 EGB05910.1 - 0.0092 15.8 0.3 0.045 13.6 0.3 2.2 1 0 0 1 1 1 1 AAA lid domain CRT-like PF08627.10 EGB05910.1 - 0.017 14.1 0.2 0.2 10.5 0.5 2.0 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 EGB05910.1 - 0.027 13.7 0.5 0.054 12.7 0.5 1.4 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport DUF3267 PF11667.8 EGB05910.1 - 0.31 11.4 1.8 1 9.7 1.8 1.8 1 0 0 1 1 1 0 Putative zincin peptidase TMEM234 PF10639.9 EGB05910.1 - 0.66 10.0 3.6 4.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 TPT PF03151.16 EGB05910.1 - 1.4 8.2 10.0 0.06 12.7 4.2 1.6 2 0 0 2 2 2 0 Triose-phosphate Transporter family Aldo_ket_red PF00248.21 EGB05911.1 - 1.4e-44 152.5 0.0 1.6e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family VCBS PF13517.6 EGB05912.1 - 2.8e-46 155.9 103.1 6.5e-10 39.5 9.8 6.2 1 1 6 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AbfS_sensor PF18225.1 EGB05912.1 - 1.5e-05 24.8 0.0 6.6 6.7 0.0 5.0 6 0 0 6 6 6 1 Sensor histidine kinase (AbfS) sensor domain HTH_31 PF13560.6 EGB05912.1 - 0.0001 22.6 0.3 9.8 6.6 0.0 5.6 5 1 1 6 6 6 1 Helix-turn-helix domain Dockerin_1 PF00404.18 EGB05912.1 - 0.0002 21.5 38.3 1.1 9.5 0.4 7.3 7 0 0 7 7 7 3 Dockerin type I domain DUF3701 PF12482.8 EGB05912.1 - 0.0018 18.3 2.5 27 4.9 0.0 5.0 5 0 0 5 5 5 0 Phage integrase protein DUF5541 PF17695.1 EGB05912.1 - 0.0033 17.8 0.0 62 4.1 0.0 5.2 3 2 3 6 6 6 0 Family of unknown function (DUF5541) NUDIX-like PF09296.11 EGB05912.1 - 0.0034 18.0 2.9 8.8 7.0 0.2 4.6 1 1 1 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain Hydrolase_4 PF12146.8 EGB05912.1 - 0.0036 16.6 2.8 10 5.3 0.0 4.2 2 2 1 4 4 4 0 Serine aminopeptidase, S33 Nrap_D5 PF17406.2 EGB05912.1 - 0.0083 15.9 0.9 12 5.6 0.0 4.2 2 1 3 5 5 5 0 Nrap protein PAP/OAS1-like domain 5 vWF_A PF12450.8 EGB05912.1 - 0.015 15.3 5.9 4.4 7.3 0.0 4.8 6 0 0 6 6 6 0 von Willebrand factor BBS2_Mid PF14783.6 EGB05912.1 - 0.069 13.2 11.6 1.6 8.8 1.3 5.8 5 1 1 6 6 6 0 Ciliary BBSome complex subunit 2, middle region DUF371 PF04027.13 EGB05912.1 - 0.099 12.6 5.5 38 4.2 0.0 4.6 6 0 0 6 6 6 0 Domain of unknown function (DUF371) Phage_r1t_holin PF16945.5 EGB05912.1 - 0.13 12.4 12.2 5.3 7.3 0.2 4.3 4 0 0 4 4 4 0 Putative lactococcus lactis phage r1t holin VPS13_mid_rpt PF16910.5 EGB05912.1 - 0.19 11.2 0.1 2.1 7.7 0.0 2.4 1 1 2 3 3 3 0 Repeating coiled region of VPS13 SyrA PF11089.8 EGB05912.1 - 0.29 11.2 6.5 1.6e+02 2.5 0.1 5.0 5 0 0 5 5 5 0 Exopolysaccharide production repressor Atracotoxin PF05353.11 EGB05912.1 - 0.92 9.6 6.5 2.1e+02 2.0 0.0 5.4 7 0 0 7 7 6 0 Delta Atracotoxin CbiA PF01656.23 EGB05912.1 - 1.4 9.0 11.8 16 5.5 0.1 4.7 4 2 1 5 5 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_S13 PF02113.15 EGB05912.1 - 4.9 5.8 15.5 1.3 7.6 2.4 3.1 1 1 3 4 4 4 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Flavokinase PF01687.17 EGB05913.1 - 8.2e-28 96.9 0.0 9e-28 96.8 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase BolA PF01722.18 EGB05914.1 - 1.4e-10 41.3 0.0 2.2e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein VCBS PF13517.6 EGB05915.1 - 1.9e-37 127.7 79.8 4.5e-10 40.0 5.0 6.1 1 1 5 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB05915.1 - 0.00058 19.9 57.7 0.015 15.4 2.3 7.5 7 0 0 7 7 7 5 FG-GAP repeat DNAP_B_exo_N PF08452.10 EGB05915.1 - 0.25 10.8 1.7 16 5.0 0.0 3.5 4 0 0 4 4 4 0 DNA polymerase family B exonuclease domain, N-terminal Peptidase_C1 PF00112.23 EGB05916.1 - 1.5e-11 44.9 3.2 1.6e-11 44.7 3.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB05916.1 - 0.048 12.4 0.9 0.049 12.4 0.9 1.0 1 0 0 1 1 1 0 Peptidase C1-like family AMP-binding PF00501.28 EGB05917.1 - 1.1e-101 340.5 0.1 1.4e-101 340.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DHQ_synthase PF01761.20 EGB05918.1 - 7.8e-56 189.1 0.0 9.7e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EGB05918.1 - 2.2e-09 37.4 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EGB05918.1 - 9e-05 21.4 0.2 0.00023 20.1 0.1 1.8 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Mito_carr PF00153.27 EGB05919.1 - 5.3e-57 189.8 0.1 2.8e-20 72.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGB05919.1 - 0.055 12.6 0.1 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Methyltransf_16 PF10294.9 EGB05920.1 - 1.3e-19 70.6 0.0 2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Sulfotransfer_3 PF13469.6 EGB05920.1 - 3.6e-12 47.2 0.4 0.00043 20.7 0.2 3.5 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB05920.1 - 1.2e-08 34.7 0.0 0.00043 19.9 0.0 3.3 2 2 0 2 2 2 2 Sulfotransferase domain FKBP_C PF00254.28 EGB05920.1 - 6e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Methyltransf_25 PF13649.6 EGB05920.1 - 1e-05 26.1 0.0 4.1e-05 24.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB05920.1 - 9.7e-05 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGB05920.1 - 0.00093 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05920.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB05920.1 - 0.0053 17.5 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGB05920.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain fn3 PF00041.21 EGB05921.1 - 1.2e-14 54.4 0.0 0.00034 20.9 0.1 5.6 5 0 0 5 5 5 3 Fibronectin type III domain Kelch_6 PF13964.6 EGB05921.1 - 1.1e-11 44.6 4.9 0.00022 21.4 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EGB05921.1 - 1.4e-06 28.1 3.9 0.12 12.4 0.1 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 EGB05921.1 - 1e-05 25.5 0.7 0.0001 22.2 0.1 5.4 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EGB05921.1 - 2.4e-05 23.8 1.6 0.018 14.6 0.0 4.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 EGB05921.1 - 7.8e-05 22.9 13.7 0.0048 17.2 0.1 7.1 5 1 0 5 5 5 2 Galactose oxidase, central domain Gly_rich PF12810.7 EGB05921.1 - 0.00014 21.9 41.7 0.00014 21.9 41.7 3.4 3 1 1 4 4 4 1 Glycine rich protein P_proprotein PF01483.20 EGB05921.1 - 0.025 14.6 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Proprotein convertase P-domain Kelch_2 PF07646.15 EGB05921.1 - 0.025 14.6 3.3 9.6 6.4 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Sulfotransfer_3 PF13469.6 EGB05922.1 - 0.017 15.5 0.4 0.16 12.3 0.3 2.6 2 1 0 2 2 2 0 Sulfotransferase family Kelch_6 PF13964.6 EGB05924.1 - 7.5e-24 83.2 0.0 2.9e-11 43.2 0.0 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 EGB05924.1 - 1.3e-18 66.3 3.8 1.3e-07 31.1 0.0 3.9 3 1 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 EGB05924.1 - 6e-17 61.4 0.8 6.8e-07 29.2 0.0 3.4 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGB05924.1 - 4.6e-16 58.1 1.6 0.00057 19.8 0.1 3.5 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EGB05924.1 - 6.9e-15 54.7 0.4 0.00071 19.5 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EGB05924.1 - 1e-14 54.4 5.7 3.5e-07 30.4 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain UCH PF00443.29 EGB05925.1 - 2e-61 207.8 0.0 2.2e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB05925.1 - 6.5e-10 39.1 0.0 9.4e-05 22.1 0.0 2.4 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EGB05925.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal Arc_C PF18162.1 EGB05925.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Arc C-lobe TF_Zn_Ribbon PF08271.12 EGB05925.1 - 0.17 11.4 0.6 0.4 10.2 0.6 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Lipase_3 PF01764.25 EGB05926.1 - 1.7e-10 40.9 1.0 2.9e-10 40.2 0.0 1.9 2 1 0 2 2 2 1 Lipase (class 3) Abhydrolase_3 PF07859.13 EGB05926.1 - 0.0036 17.2 0.3 0.0085 16.0 0.3 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB05926.1 - 4 8.0 25.5 0.091 13.3 13.6 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family Pkinase PF00069.25 EGB05929.1 - 4e-56 190.3 0.0 8.7e-56 189.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05929.1 - 1.6e-26 93.1 0.0 2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05929.1 - 4.3e-05 23.0 0.0 0.0011 18.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB05929.1 - 0.0001 21.2 0.0 0.00014 20.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB05929.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VPS9 PF02204.18 EGB05930.1 - 1.2e-22 80.1 0.0 1.3e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Amidohydro_1 PF01979.20 EGB05931.1 - 5.4e-73 246.3 1.0 8.5e-73 245.6 1.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EGB05931.1 - 5.3e-51 172.0 1.4 1.8e-50 170.3 1.4 2.0 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 EGB05931.1 - 1e-41 141.2 1.9 1.8e-41 140.5 0.1 2.4 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 EGB05931.1 - 4.3e-38 129.3 0.1 1.3e-37 127.7 0.1 1.9 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 EGB05931.1 - 9.2e-09 35.3 0.5 2.5e-06 27.2 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family cobW PF02492.19 EGB05932.1 - 1.5e-32 112.6 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGB05932.1 - 2.4e-05 23.5 0.4 0.02 13.8 0.1 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 EGB05932.1 - 0.014 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EGB05932.1 - 0.025 15.0 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EGB05932.1 - 0.049 13.6 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EGB05932.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase TIP49 PF06068.13 EGB05932.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 EGB05932.1 - 0.075 13.5 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EGB05932.1 - 0.09 13.3 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EGB05932.1 - 0.19 11.7 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Actin PF00022.19 EGB05933.1 - 1.1e-146 488.6 0.0 3.6e-146 487.0 0.0 1.6 1 1 0 1 1 1 1 Actin TauD PF02668.16 EGB05934.1 - 1.8e-25 90.3 0.0 2.7e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EGB05934.1 - 0.0014 17.8 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 CsiD AMPK1_CBM PF16561.5 EGB05935.1 - 3.6e-33 113.6 0.7 5.9e-33 112.9 0.7 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGB05935.1 - 1.9e-23 82.5 1.8 2.9e-23 81.9 1.8 1.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain WD40 PF00400.32 EGB05935.1 - 0.00021 22.0 4.6 0.13 13.2 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat WD40_like PF17005.5 EGB05935.1 - 0.012 14.9 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 WD40-like domain Myb_DNA-binding PF00249.31 EGB05936.1 - 5.2e-24 84.2 2.9 2.5e-11 43.6 0.2 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB05936.1 - 1.8e-21 76.1 0.7 2.1e-13 50.3 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB05936.1 - 0.0034 17.2 0.2 0.014 15.3 0.0 1.9 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 EGB05936.1 - 0.0088 16.1 2.0 0.019 15.1 0.1 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Sel1 PF08238.12 EGB05937.1 - 9e-28 96.1 7.2 5.3e-05 23.7 0.0 6.4 6 0 0 6 6 6 6 Sel1 repeat TPR_12 PF13424.6 EGB05937.1 - 3.2e-05 24.1 9.4 4.7e-05 23.6 0.3 4.2 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05937.1 - 0.0084 15.9 11.1 0.2 11.5 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05937.1 - 0.03 14.4 14.0 1.2 9.4 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05937.1 - 0.82 10.4 11.9 1.6 9.4 0.3 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat Arf PF00025.21 EGB05938.1 - 1.2e-59 200.7 0.2 2.5e-45 154.1 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EGB05938.1 - 2.3e-12 46.7 1.7 1.1e-06 28.0 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit Roc PF08477.13 EGB05938.1 - 1.1e-11 45.0 0.0 4.7e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGB05938.1 - 2.2e-11 43.6 0.0 1.2e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGB05938.1 - 8.1e-10 38.4 0.0 4.4e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGB05938.1 - 3.4e-09 36.5 0.0 0.0001 22.0 0.0 2.1 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.23 EGB05938.1 - 7.9e-06 25.9 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB05938.1 - 0.00011 21.9 0.3 0.02 14.4 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EGB05938.1 - 0.0011 19.5 0.1 0.0031 18.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EGB05938.1 - 0.0072 16.1 0.1 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGB05938.1 - 0.039 13.9 0.2 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DLIC PF05783.11 EGB05938.1 - 0.12 11.2 0.2 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1_Xtn PF16897.5 EGB05938.1 - 0.13 12.2 0.1 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_14 PF13173.6 EGB05938.1 - 0.15 12.1 0.0 0.74 9.9 0.0 1.9 1 1 0 2 2 2 0 AAA domain Rad10 PF03834.14 EGB05938.1 - 0.29 11.2 0.7 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Anophelin PF10731.9 EGB05939.1 - 8.5 6.3 9.1 5.6 6.9 3.1 3.1 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito Peptidase_M41 PF01434.18 EGB05940.1 - 4.1e-61 206.2 0.1 6.6e-61 205.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGB05940.1 - 8.9e-42 142.6 0.0 1.5e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB05940.1 - 1.5e-11 43.9 0.4 3.7e-11 42.7 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EGB05940.1 - 3.7e-07 30.5 0.0 2.2e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 EGB05940.1 - 0.0002 21.6 0.5 0.077 13.3 0.1 3.0 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 EGB05940.1 - 0.0017 17.6 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EGB05940.1 - 0.0033 17.4 0.0 0.0095 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGB05940.1 - 0.0065 16.6 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGB05940.1 - 0.0069 16.1 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGB05940.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EGB05940.1 - 0.063 13.7 1.8 0.8 10.1 0.1 2.8 2 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 EGB05940.1 - 0.065 12.6 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGB05940.1 - 0.078 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGB05940.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGB05940.1 - 0.14 12.5 0.9 22 5.3 0.4 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGB05940.1 - 0.2 11.1 0.1 0.73 9.3 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EGB05940.1 - 0.24 10.8 1.1 1.6 8.2 0.4 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EGB05940.1 - 0.57 9.9 2.6 14 5.3 0.4 2.5 2 0 0 2 2 2 0 AAA domain DUF616 PF04765.13 EGB05941.1 - 1.2e-06 28.0 0.0 0.00042 19.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF616) Sulfotransfer_3 PF13469.6 EGB05942.1 - 4.2e-12 46.9 0.3 1.1e-11 45.6 0.1 1.8 2 0 0 2 2 2 1 Sulfotransferase family Rieske PF00355.26 EGB05942.1 - 2.5e-11 43.4 0.7 1.3e-10 41.1 0.7 2.1 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EGB05942.1 - 1.8e-10 40.7 0.0 0.00036 20.4 0.0 2.4 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain AmoC PF04896.12 EGB05943.1 - 0.045 13.0 1.3 0.094 12.0 1.3 1.5 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C Proteasome PF00227.26 EGB05944.1 - 1.3e-27 96.5 0.0 1.5e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB05944.1 - 3.9e-11 42.4 0.1 6.3e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sulfatase PF00884.23 EGB05945.1 - 1.1e-44 153.2 0.1 1.4e-44 152.8 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB05945.1 - 2.8e-06 27.2 0.2 6.6e-06 25.9 0.2 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EGB05945.1 - 0.003 18.3 0.0 0.0059 17.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 EGB05945.1 - 0.19 10.8 0.3 0.36 9.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) TB2_DP1_HVA22 PF03134.19 EGB05946.1 - 1.3e-05 25.0 0.1 0.00046 20.1 0.0 2.9 2 1 0 2 2 2 1 TB2/DP1, HVA22 family PsbX PF06596.11 EGB05946.1 - 0.43 10.6 2.5 1.7 8.7 2.5 2.1 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Methyltransf_11 PF08241.12 EGB05947.1 - 1.2e-10 41.8 0.1 3e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB05947.1 - 3.8e-07 30.7 0.1 1.7e-06 28.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05947.1 - 9.5e-06 25.5 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB05947.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-ZPR1 PF03367.13 EGB05948.1 - 9.8e-104 344.0 0.0 2.4e-51 173.7 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EGB05948.1 - 0.00065 19.7 2.7 0.8 9.7 1.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EGB05948.1 - 0.076 13.1 10.4 5.5 7.2 1.3 4.2 4 0 0 4 4 4 0 Zinc ribbon domain Terminase_GpA PF05876.12 EGB05948.1 - 0.16 10.5 0.3 0.28 9.7 0.3 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.6 EGB05948.1 - 0.18 12.2 10.4 0.4 11.1 4.7 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.11 EGB05948.1 - 1.5 8.8 9.4 14 5.7 0.8 3.4 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 EGB05948.1 - 3 7.9 7.4 2.1 8.4 3.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 EGB05948.1 - 3.4 7.5 12.6 1.2 9.0 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf_UBZ PF18439.1 EGB05948.1 - 3.5 7.3 6.5 58 3.4 0.2 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 EGB05948.1 - 3.9 7.5 6.5 9.4 6.3 1.4 2.5 2 0 0 2 2 2 0 zinc-ribbons Pkinase PF00069.25 EGB05949.1 - 4.1e-58 196.8 0.0 4.6e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05949.1 - 2e-28 99.4 0.0 2.3e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB05949.1 - 2e-07 30.6 0.0 3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB05949.1 - 0.041 13.8 3.1 0.041 13.8 1.1 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB05949.1 - 0.081 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ldh_2 PF02615.14 EGB05950.1 - 3.5e-52 177.6 0.6 3.9e-52 177.5 0.6 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ThylakoidFormat PF11264.8 EGB05951.1 - 1.7e-23 83.5 1.6 9.1e-23 81.1 0.0 2.5 2 1 0 2 2 2 1 Thylakoid formation protein EGF_2 PF07974.13 EGB05952.1 - 2.8e-14 53.2 55.5 2.8e-05 24.4 8.2 5.2 4 1 0 4 4 4 4 EGF-like domain Laminin_EGF PF00053.24 EGB05952.1 - 2.4e-05 24.4 43.2 0.23 11.6 3.6 4.6 2 1 2 4 4 4 3 Laminin EGF domain EGF_alliinase PF04863.13 EGB05952.1 - 0.00099 19.5 6.9 0.00099 19.5 6.9 5.6 4 2 1 5 5 5 3 Alliinase EGF-like domain EGF PF00008.27 EGB05952.1 - 0.0019 18.5 45.1 0.3 11.5 1.4 6.1 6 0 0 6 6 6 4 EGF-like domain S_locus_glycop PF00954.20 EGB05952.1 - 0.043 14.4 17.2 0.31 11.6 1.8 3.3 3 0 0 3 3 3 0 S-locus glycoprotein domain EGF_3 PF12947.7 EGB05952.1 - 3.9 7.8 28.9 0.77 10.0 1.1 5.2 4 1 0 4 4 4 0 EGF domain EF-hand_1 PF00036.32 EGB05953.1 - 3.7e-12 44.9 6.1 1e-05 24.7 0.7 3.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EGB05953.1 - 6.2e-12 44.4 4.3 0.00081 19.1 0.4 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EGB05953.1 - 9.2e-12 44.6 1.0 2.1e-05 24.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EGB05953.1 - 1.7e-10 41.2 0.0 9.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB05953.1 - 7.9e-10 37.8 3.0 0.00015 21.1 0.7 2.6 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 EGB05953.1 - 0.06 13.2 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 EF hand ABC1 PF03109.16 EGB05954.1 - 2.8e-28 98.5 0.0 4.7e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB05954.1 - 1e-06 28.8 1.9 3.7e-05 23.8 0.2 2.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGB05954.1 - 0.00061 19.2 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Zein-binding PF04576.15 EGB05954.1 - 0.11 12.8 0.9 0.57 10.5 0.4 2.3 2 0 0 2 2 2 0 Zein-binding U-box PF04564.15 EGB05956.1 - 2.6e-42 142.8 0.1 3.6e-20 71.9 0.1 2.7 2 0 0 2 2 2 2 U-box domain OST-HTH PF12872.7 EGB05956.1 - 1.5e-14 53.6 0.0 0.00027 20.7 0.0 4.4 4 0 0 4 4 4 4 OST-HTH/LOTUS domain Ribosomal_L9_N PF01281.19 EGB05956.1 - 9.5e-10 37.9 0.0 2.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain zf-Nse PF11789.8 EGB05956.1 - 2.5e-09 36.8 0.0 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit RRM_1 PF00076.22 EGB05956.1 - 7.1e-08 32.2 0.0 0.003 17.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-NOSIP PF15906.5 EGB05956.1 - 1.3e-07 31.7 0.0 0.012 15.8 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGB05956.1 - 3.2e-05 23.9 0.0 0.062 13.3 0.0 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-CCCH PF00642.24 EGB05956.1 - 0.00014 21.7 1.2 0.00025 20.9 1.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGB05956.1 - 0.00025 21.0 2.8 0.00054 19.9 2.8 1.6 1 0 0 1 1 1 1 Zinc finger domain CSD PF00313.22 EGB05956.1 - 0.008 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCCH_2 PF14608.6 EGB05956.1 - 0.013 16.0 2.0 0.023 15.2 2.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGB05956.1 - 0.087 12.7 1.6 0.16 11.8 1.6 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGB05956.1 - 0.22 11.7 0.0 0.45 10.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger containing family Pkinase PF00069.25 EGB05957.1 - 6.4e-54 183.1 0.0 7.7e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05957.1 - 4e-27 95.1 0.0 5.5e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05957.1 - 0.0002 21.4 4.3 0.00048 20.1 4.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB05957.1 - 0.026 13.8 0.0 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 EGB05957.1 - 0.24 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 NolV PF06635.12 EGB05957.1 - 5.2 6.4 8.3 12 5.2 1.1 2.8 3 0 0 3 3 3 0 Nodulation protein NolV TPR_12 PF13424.6 EGB05958.1 - 1.7e-26 92.3 7.7 4.1e-13 49.4 0.2 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGB05958.1 - 3.4e-25 87.1 9.0 2.4e-06 27.2 0.3 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGB05958.1 - 3.2e-12 45.6 4.2 0.0078 16.2 0.0 4.4 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGB05958.1 - 4.4e-10 38.9 7.6 0.019 14.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB05958.1 - 3.1e-09 36.7 4.5 3.6e-09 36.5 3.3 1.5 1 1 1 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 EGB05958.1 - 5.9e-09 36.0 15.0 0.00046 20.8 1.0 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB05958.1 - 6.2e-09 35.3 12.2 0.01 15.9 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB05958.1 - 5.9e-08 33.1 7.3 2.2e-05 24.9 3.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB05958.1 - 4.1e-06 27.3 13.6 0.032 14.9 0.1 4.0 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB05958.1 - 8.6e-06 25.6 5.7 1.1 9.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGB05958.1 - 0.00025 21.4 13.6 0.02 15.5 1.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB05958.1 - 0.071 13.8 3.4 5.2 7.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 EGB05958.1 - 0.071 13.4 1.6 0.094 13.0 0.4 1.9 3 0 0 3 3 2 0 Tetratrico peptide repeat TPR_17 PF13431.6 EGB05958.1 - 0.65 10.5 3.4 6.3 7.4 0.2 3.9 5 1 0 5 5 5 0 Tetratricopeptide repeat Neur_chan_LBD PF02931.23 EGB05960.1 - 8.8e-21 74.3 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 EGB05960.1 - 2.3e-10 40.9 0.0 3.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.32 EGB05960.1 - 7.6e-08 31.4 0.1 0.0018 17.7 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB05960.1 - 8.9e-08 32.5 0.5 8.9e-08 32.5 0.5 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB05960.1 - 9.1e-07 28.3 1.7 0.00082 19.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EGB05960.1 - 0.0078 15.7 0.1 3.4 7.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 EGB05960.1 - 0.019 14.8 0.5 0.22 11.4 0.0 2.5 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 EGB05960.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Polysacc_synt_C PF14667.6 EGB05961.1 - 2.6e-08 34.0 4.7 2.6e-08 34.0 4.7 3.3 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 EGB05961.1 - 4.4e-05 22.3 2.6 7.4e-05 21.5 1.9 1.6 1 1 0 1 1 1 1 Lipid II flippase MurJ UPF0220 PF05255.11 EGB05961.1 - 0.067 12.7 0.1 0.067 12.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) PALP PF00291.25 EGB05962.1 - 8.2e-63 212.5 0.6 9.3e-63 212.4 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 EGB05962.1 - 0.0039 17.2 0.4 0.059 13.4 0.1 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase SNF2_N PF00176.23 EGB05963.1 - 3.3e-41 141.2 0.0 5.8e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB05963.1 - 4.9e-12 46.2 0.0 8.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB05963.1 - 6e-09 36.1 0.0 1.4e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB05963.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EGB05963.1 - 0.073 13.3 0.0 0.36 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 EGB05964.1 - 5.5e-27 94.8 0.0 6.6e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05964.1 - 5.3e-26 91.4 0.0 6.2e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05964.1 - 0.014 15.4 6.1 0.014 15.3 0.4 2.8 1 1 2 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGB05964.1 - 0.1 12.2 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 EGB05964.1 - 0.23 10.5 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Lectin_C PF00059.21 EGB05965.1 - 3.6e-05 24.5 0.6 6.1e-05 23.7 0.6 1.4 1 0 0 1 1 1 1 Lectin C-type domain Aa_trans PF01490.18 EGB05965.1 - 0.00027 19.8 1.1 0.00051 18.9 1.1 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L14 PF00238.19 EGB05966.1 - 2e-34 118.3 0.0 2.4e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF3846 PF12957.7 EGB05966.1 - 0.068 13.5 0.0 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) Baculo_PEP_C PF04513.12 EGB05968.1 - 4.7e-06 26.7 19.4 0.0016 18.5 2.0 5.3 4 1 0 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus PspB PF06667.12 EGB05968.1 - 0.011 15.7 0.1 0.11 12.5 0.1 2.9 1 0 0 1 1 1 0 Phage shock protein B TolA_bind_tri PF16331.5 EGB05968.1 - 1.2 9.3 0.0 1.2 9.3 0.0 7.6 6 2 3 9 9 9 0 TolA binding protein trimerisation SHE3 PF17078.5 EGB05968.1 - 1.3 8.7 44.6 0.038 13.7 10.9 4.9 2 1 2 4 4 4 0 SWI5-dependent HO expression protein 3 E1-E2_ATPase PF00122.20 EGB05969.1 - 6.1e-21 74.7 0.3 1.4e-20 73.6 0.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGB05969.1 - 4.1e-15 56.6 2.3 1.7e-06 28.5 1.9 3.3 3 2 0 3 3 3 2 haloacid dehalogenase-like hydrolase DSBA PF01323.20 EGB05970.1 - 6.5e-24 84.8 0.0 8.4e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 EGB05970.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 EGB05970.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Myb_DNA-binding PF00249.31 EGB05971.1 - 1.1e-22 79.9 3.6 3.2e-07 30.4 0.0 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB05971.1 - 7.5e-11 42.1 0.1 0.036 14.3 0.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGB05971.1 - 0.0023 18.0 0.0 4.8 7.2 0.0 3.2 3 0 0 3 3 3 2 SLIDE fn3 PF00041.21 EGB05971.1 - 0.0024 18.2 1.9 0.033 14.5 0.1 3.3 2 1 1 3 3 3 1 Fibronectin type III domain WD40 PF00400.32 EGB05972.1 - 3.8e-07 30.7 6.2 0.24 12.4 0.1 6.5 7 1 0 7 7 7 3 WD domain, G-beta repeat Abhydrolase_1 PF00561.20 EGB05973.1 - 8e-22 78.1 0.1 1.3e-21 77.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB05973.1 - 4.6e-08 32.6 0.2 4e-06 26.3 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGB05973.1 - 0.00015 22.4 17.0 0.00032 21.4 17.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGB05973.1 - 0.031 13.7 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAP_fibrillin PF04755.12 EGB05974.1 - 3.4e-08 33.7 0.0 2.4e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 PAP_fibrillin 2OG-FeII_Oxy PF03171.20 EGB05974.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Na_Ca_ex PF01699.24 EGB05975.1 - 4.2e-14 52.8 1.2 4.4e-14 52.7 1.2 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 EGB05976.1 - 3.3e-23 82.3 14.5 4.4e-23 81.9 14.5 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein CbiQ PF02361.16 EGB05976.1 - 0.038 13.6 2.8 0.086 12.5 0.1 2.1 2 0 0 2 2 2 0 Cobalt transport protein DUF4022 PF13214.6 EGB05976.1 - 0.045 14.0 1.6 0.068 13.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) Methyltransf_11 PF08241.12 EGB05977.1 - 5.3e-19 68.7 0.0 8.6e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB05977.1 - 1.9e-18 67.0 0.0 3.5e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB05977.1 - 3.1e-13 49.9 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB05977.1 - 2.1e-12 47.1 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB05977.1 - 1.1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EGB05977.1 - 2.4e-10 41.0 0.0 3.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB05977.1 - 2.1e-06 27.2 0.0 3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family OsmC PF02566.19 EGB05977.1 - 0.044 14.3 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 OsmC-like protein MTS PF05175.14 EGB05977.1 - 0.05 13.1 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Metallophos PF00149.28 EGB05978.1 - 4.9e-07 30.4 0.2 6.9e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA-synt_His PF13393.6 EGB05979.1 - 6.2e-46 157.1 0.0 9.9e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGB05979.1 - 3.7e-12 46.2 0.0 6.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGB05979.1 - 5.9e-08 32.9 0.0 7.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EGB05979.1 - 0.023 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Melibiase_2 PF16499.5 EGB05980.1 - 1.4e-69 234.4 2.1 2.5e-69 233.6 2.1 1.4 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGB05980.1 - 7.4e-17 61.2 0.1 2.1e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGB05980.1 - 0.00018 20.6 0.0 0.00047 19.2 0.0 1.6 2 0 0 2 2 2 1 Melibiase Melibiase_2_C PF17450.2 EGB05980.1 - 0.0027 17.9 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain TrbC PF04956.13 EGB05980.1 - 0.07 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 TrbC/VIRB2 family DnaJ PF00226.31 EGB05981.1 - 1.4e-18 66.8 3.9 1.5e-18 66.6 3.9 1.0 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGB05981.1 - 0.0041 17.0 0.1 0.0077 16.1 0.1 1.6 1 1 0 1 1 1 1 A repeated domain in UCH-protein DUF1217 PF06748.12 EGB05981.1 - 0.064 13.3 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) Proteasome PF00227.26 EGB05982.1 - 2.2e-56 190.4 0.3 3e-56 189.9 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB05982.1 - 8.2e-14 51.0 0.2 1.6e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pribosyltran_N PF13793.6 EGB05983.1 - 4e-40 136.4 0.0 3.8e-38 130.0 0.0 2.2 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGB05983.1 - 4.4e-30 105.1 0.5 9.3e-30 104.0 0.5 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGB05983.1 - 2.5e-15 56.3 2.9 2.9e-13 49.6 1.3 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain Symplekin_C PF12295.8 EGB05984.1 - 4.7e-47 160.5 0.0 8.4e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal CTXphi_pIII-N1 PF16710.5 EGB05984.1 - 0.057 13.5 0.2 17 5.5 0.0 2.6 2 0 0 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Cohesin_HEAT PF12765.7 EGB05984.1 - 0.065 13.5 0.4 0.19 12.1 0.4 1.8 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion FSH1 PF03959.13 EGB05984.1 - 0.13 11.9 0.0 21 4.7 0.0 2.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Pkinase PF00069.25 EGB05987.1 - 6.1e-58 196.3 0.0 8.1e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB05987.1 - 6.4e-24 84.6 0.0 1.6e-23 83.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB05987.1 - 5.2e-07 29.8 1.7 5.2e-07 29.8 1.7 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB05987.1 - 3.2e-05 23.4 0.0 6.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB05987.1 - 0.00085 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGB05987.1 - 0.0052 16.4 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGB05987.1 - 0.21 10.9 0.0 0.68 9.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like EF-hand_1 PF00036.32 EGB05988.1 - 1.5e-15 55.5 0.0 0.0014 18.0 0.0 5.4 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EGB05988.1 - 5.7e-15 55.5 0.1 1.7e-08 34.8 0.2 4.2 2 1 3 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 EGB05988.1 - 2.7e-14 51.8 0.1 0.054 13.4 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EGB05988.1 - 8.5e-11 41.5 0.2 9.9e-06 25.3 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair Tyrosinase PF00264.20 EGB05988.1 - 2.1e-08 34.7 0.2 0.00032 21.0 0.0 2.4 2 0 0 2 2 2 2 Common central domain of tyrosinase EF-hand_5 PF13202.6 EGB05988.1 - 3.7e-05 23.0 2.4 0.27 10.8 0.0 4.8 5 0 0 5 5 5 2 EF hand UvrD-helicase PF00580.21 EGB05989.1 - 5.8e-12 45.8 0.0 2.2e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EGB05989.1 - 2.3e-06 27.4 0.0 5.3e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EGB05989.1 - 2.5e-06 27.9 0.0 1.3e-05 25.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB05989.1 - 0.00013 21.8 0.0 0.31 10.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain UvrD_C PF13361.6 EGB05989.1 - 0.00036 20.0 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 EGB05989.1 - 0.0012 18.3 0.0 0.55 9.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.18 EGB05989.1 - 0.013 15.2 0.0 4.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGB05989.1 - 0.055 13.7 0.0 9.6 6.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain DEC-1_N PF04625.13 EGB05989.1 - 0.09 11.8 2.0 0.27 10.2 1.5 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Tyrosinase PF00264.20 EGB05990.1 - 2.8e-14 53.9 0.1 2.8e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Common central domain of tyrosinase TIG PF01833.24 EGB05991.1 - 1e-45 153.7 36.5 3e-07 30.4 0.0 13.9 14 0 0 14 14 14 12 IPT/TIG domain Ephrin_rec_like PF07699.13 EGB05991.1 - 1e-16 60.4 179.5 6.3e-05 22.6 1.3 16.0 8 3 9 17 17 17 11 Putative ephrin-receptor like Cupin_4 PF08007.12 EGB05991.1 - 8.1e-12 45.2 0.3 1.6e-11 44.3 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB05991.1 - 0.0081 15.9 0.2 0.042 13.6 0.0 2.3 2 0 0 2 2 2 1 Cupin domain TRP PF06011.12 EGB05991.1 - 0.011 14.5 9.2 0.13 11.0 7.0 2.7 2 1 0 2 2 2 0 Transient receptor potential (TRP) ion channel 7TM_GPCR_Srbc PF10316.9 EGB05991.1 - 0.042 13.4 0.9 0.094 12.2 0.9 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc UPF0242 PF06785.11 EGB05991.1 - 0.1 12.7 0.3 14 5.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Neur_chan_LBD PF02931.23 EGB05992.1 - 1.6e-18 67.0 0.0 2.4e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain LRR_6 PF13516.6 EGB05993.1 - 3.2e-16 57.9 9.1 0.55 10.4 0.0 9.0 9 0 0 9 9 9 5 Leucine Rich repeat EF-hand_1 PF00036.32 EGB05993.1 - 1.8e-09 36.5 0.0 0.0028 17.1 0.0 2.7 2 0 0 2 2 2 2 EF hand LRR_1 PF00560.33 EGB05993.1 - 2e-06 27.6 0.2 33 5.6 0.0 7.4 8 0 0 8 8 8 0 Leucine Rich Repeat EF-hand_7 PF13499.6 EGB05993.1 - 2.9e-06 27.6 0.0 9.6e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair LRR_4 PF12799.7 EGB05993.1 - 3.6e-06 27.2 1.2 3.4 8.2 0.0 5.2 2 2 5 7 7 7 2 Leucine Rich repeats (2 copies) EF-hand_5 PF13202.6 EGB05993.1 - 6.7e-06 25.4 0.0 0.044 13.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB05993.1 - 1e-05 25.3 0.0 0.00011 22.0 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB05993.1 - 2e-05 24.1 0.0 0.082 12.9 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain DUF4476 PF14771.6 EGB05993.1 - 7.7e-05 22.9 0.0 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) LRR_8 PF13855.6 EGB05993.1 - 0.00027 20.6 7.1 2.5 7.9 0.0 5.5 2 2 3 5 5 5 3 Leucine rich repeat NAM-associated PF14303.6 EGB05993.1 - 0.9 10.2 13.2 1.7 9.4 0.1 2.9 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain TRP PF06011.12 EGB05994.1 - 4.1e-08 32.4 2.7 6.5e-08 31.7 2.7 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Ephrin_rec_like PF07699.13 EGB05994.1 - 2.4e-06 27.2 23.3 0.00096 18.9 6.7 3.7 2 1 1 3 3 3 3 Putative ephrin-receptor like DUF3792 PF12670.7 EGB05994.1 - 0.71 10.1 7.2 2.8 8.1 7.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) MSC PF09402.10 EGB05994.1 - 5 6.5 4.5 0.88 9.0 0.5 1.6 1 1 0 2 2 2 0 Man1-Src1p-C-terminal domain E1-E2_ATPase PF00122.20 EGB05995.1 - 7.6e-43 146.1 3.2 7.6e-43 146.1 3.2 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGB05995.1 - 2.4e-29 102.3 0.5 2.4e-29 102.3 0.5 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGB05995.1 - 1.6e-15 58.0 6.5 5.5e-12 46.4 2.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGB05995.1 - 5.3e-13 48.9 0.0 1.7e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGB05995.1 - 1.1e-10 41.0 0.0 2.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FliMN_C PF01052.20 EGB05995.1 - 0.016 15.2 0.2 0.057 13.4 0.2 1.9 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Hydrolase_3 PF08282.12 EGB05995.1 - 0.031 14.0 0.2 0.053 13.3 0.2 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ninjurin PF04923.12 EGB05995.1 - 0.41 10.6 3.2 1.5 8.8 1.7 2.4 2 0 0 2 2 2 0 Ninjurin AAA PF00004.29 EGB05996.1 - 9.4e-42 142.6 0.0 1.4e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB05996.1 - 1e-08 35.7 0.2 1.4e-08 35.3 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGB05996.1 - 6.4e-07 29.3 0.0 1.9e-06 27.7 0.0 1.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB05996.1 - 1.4e-06 28.7 0.0 0.0016 18.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 EGB05996.1 - 1.1e-05 25.5 0.0 7.3e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGB05996.1 - 1.8e-05 24.9 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGB05996.1 - 0.00014 21.3 0.2 0.0004 19.8 0.1 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGB05996.1 - 0.00024 21.1 0.0 0.00055 20.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 EGB05996.1 - 0.0003 20.1 0.1 0.00086 18.6 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 EGB05996.1 - 0.00057 20.1 0.1 0.00085 19.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB05996.1 - 0.0008 20.0 0.0 0.0016 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGB05996.1 - 0.00081 19.7 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.6 EGB05996.1 - 0.0009 19.7 0.0 0.0018 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGB05996.1 - 0.00097 18.9 0.0 0.0019 17.9 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 EGB05996.1 - 0.0018 18.5 0.1 0.0046 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EGB05996.1 - 0.0032 17.4 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 EGB05996.1 - 0.0053 16.5 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EGB05996.1 - 0.0054 17.2 0.0 0.025 15.1 0.0 1.9 1 1 1 2 2 2 1 ABC transporter AAA_25 PF13481.6 EGB05996.1 - 0.0058 16.2 0.7 0.18 11.3 0.1 2.4 1 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGB05996.1 - 0.0061 15.9 0.1 0.022 14.0 0.1 2.0 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.6 EGB05996.1 - 0.0063 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGB05996.1 - 0.01 15.6 0.0 0.037 13.7 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 EGB05996.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGB05996.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 EGB05996.1 - 0.028 13.6 0.0 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGB05996.1 - 0.032 13.7 0.0 0.074 12.6 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 EGB05996.1 - 0.033 14.3 0.0 0.058 13.5 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGB05996.1 - 0.038 14.3 0.0 0.057 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGB05996.1 - 0.04 13.1 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.11 EGB05996.1 - 0.045 13.6 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 EGB05996.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.6 EGB05996.1 - 0.083 12.7 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EGB05996.1 - 0.094 12.4 0.0 0.65 9.7 0.0 1.9 1 1 1 2 2 2 0 Thymidylate kinase AAA_30 PF13604.6 EGB05996.1 - 0.098 12.4 0.1 0.4 10.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EGB05996.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Hydin_ADK PF17213.3 EGB05996.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ATPase PF06745.13 EGB05996.1 - 0.16 11.3 0.0 0.53 9.6 0.0 1.7 2 0 0 2 2 2 0 KaiC SRPRB PF09439.10 EGB05996.1 - 0.19 11.1 0.0 0.51 9.7 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit LRR_6 PF13516.6 EGB05997.1 - 4.7e-15 54.3 7.6 0.0049 16.8 0.1 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 EGB05997.1 - 9.8e-07 29.0 4.0 0.0049 17.3 0.0 5.1 3 2 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB05997.1 - 0.00027 20.5 0.0 0.0023 17.5 0.0 2.5 3 0 0 3 3 3 1 Leucine-rich repeat EF-hand_8 PF13833.6 EGB05997.1 - 0.024 14.5 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair LRR_8 PF13855.6 EGB05997.1 - 0.076 12.8 7.8 10 6.0 0.2 4.7 3 2 0 3 3 3 0 Leucine rich repeat DcpS_C PF11969.8 EGB05998.1 - 0.077 13.5 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Amidohydro_1 PF01979.20 EGB05999.1 - 2.6e-51 175.0 0.0 3.1e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGB05999.1 - 4.7e-10 39.5 0.8 1.1e-06 28.5 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EGB05999.1 - 0.0041 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase BTAD PF03704.17 EGB05999.1 - 0.067 13.6 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain AhpC-TSA_2 PF13911.6 EGB06000.1 - 1e-07 32.1 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 EGB06000.1 - 1.5e-05 24.8 0.0 0.038 13.7 0.0 2.2 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 EGB06000.1 - 0.05 13.5 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family TraF PF13728.6 EGB06000.1 - 0.096 12.5 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 F plasmid transfer operon protein Myosin_head PF00063.21 EGB06001.1 - 1e-158 529.6 0.0 2.4e-158 528.4 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB06001.1 - 9.5e-05 22.8 0.6 0.0029 18.0 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGB06001.1 - 0.0011 19.3 0.1 0.0067 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 EGB06001.1 - 0.049 12.5 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EGB06001.1 - 0.19 12.1 0.0 0.51 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Dzip-like_N PF13815.6 EGB06002.1 - 7.5e-25 87.2 1.3 7.5e-25 87.2 1.3 1.8 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal ubiquitin PF00240.23 EGB06002.1 - 0.00094 18.9 0.0 0.75 9.6 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin family TolA_bind_tri PF16331.5 EGB06002.1 - 0.014 15.4 1.3 0.32 11.1 0.1 3.0 2 0 0 2 2 2 0 TolA binding protein trimerisation Rad60-SLD PF11976.8 EGB06002.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1664 PF07889.12 EGB06002.1 - 0.11 12.5 2.3 19 5.3 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) DUF2894 PF11445.8 EGB06002.1 - 0.79 10.2 11.7 1.4 9.4 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2894) UQ_con PF00179.26 EGB06004.1 - 2.3e-19 69.5 0.0 3e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGB06004.1 - 0.16 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain Glyco_transf_20 PF00982.21 EGB06005.1 - 7.8e-98 328.2 0.0 1.3e-97 327.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGB06005.1 - 4.9e-39 133.8 0.0 1.9e-38 131.9 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase DUF3863 PF12979.7 EGB06005.1 - 0.034 13.0 0.0 2.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3863) FYVE PF01363.21 EGB06006.1 - 4.3e-08 33.2 20.9 1e-06 28.8 9.2 2.6 2 0 0 2 2 2 2 FYVE zinc finger Lipase_3 PF01764.25 EGB06006.1 - 0.0031 17.4 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) zf-C2HC_2 PF13913.6 EGB06006.1 - 1.8 8.6 7.8 2.2 8.3 2.8 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-AN1 PF01428.16 EGB06006.1 - 5.5 7.2 14.9 0.29 11.3 1.1 3.5 3 0 0 3 3 3 0 AN1-like Zinc finger LPMO_10 PF03067.15 EGB06007.1 - 7e-05 23.6 2.8 0.00016 22.4 0.2 2.5 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FSH1 PF03959.13 EGB06008.1 - 2.9e-20 72.8 0.0 5.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MMR_HSR1 PF01926.23 EGB06008.1 - 2.3e-15 56.7 0.0 6.9e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_C PF08438.10 EGB06008.1 - 2e-10 41.2 0.1 1.4e-08 35.3 0.0 3.5 2 1 0 2 2 2 1 GTPase of unknown function C-terminal Ion_trans PF00520.31 EGB06008.1 - 0.00012 21.4 8.7 0.00019 20.8 8.7 1.2 1 0 0 1 1 1 1 Ion transport protein FeoB_N PF02421.18 EGB06008.1 - 0.00081 18.9 0.0 0.078 12.5 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B RWD PF05773.22 EGB06008.1 - 0.029 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain Dynamin_N PF00350.23 EGB06008.1 - 0.25 11.4 0.2 0.65 10.0 0.2 1.7 1 0 0 1 1 1 0 Dynamin family Methyltransf_15 PF09445.10 EGB06009.1 - 1.9e-16 60.1 0.3 2.2e-16 59.8 0.3 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EGB06009.1 - 1.8e-06 28.6 0.5 2.7e-06 28.0 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGB06009.1 - 4.1e-06 26.7 0.0 4.6e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 EGB06009.1 - 0.00024 20.8 2.7 0.0056 16.4 2.7 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 EGB06009.1 - 0.00044 19.7 0.7 0.00047 19.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGB06009.1 - 0.00046 20.0 0.4 0.00056 19.7 0.4 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB06009.1 - 0.0017 18.9 0.1 0.0031 18.1 0.1 1.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGB06009.1 - 0.0073 15.9 0.5 0.0082 15.7 0.5 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGB06009.1 - 0.0074 16.2 0.1 0.009 15.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB06009.1 - 0.014 15.0 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 EGB06009.1 - 0.022 14.1 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Disulph_isomer PF06491.11 EGB06009.1 - 0.07 13.2 0.1 0.083 13.0 0.1 1.1 1 0 0 1 1 1 0 Disulphide isomerase Methyltransf_29 PF03141.16 EGB06009.1 - 0.13 10.8 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase tRNA_U5-meth_tr PF05958.11 EGB06009.1 - 0.19 10.7 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase YHYH PF14240.6 EGB06010.1 - 1.4e-16 61.0 0.1 7e-15 55.5 0.0 2.3 1 1 1 2 2 2 2 YHYH protein PPR_2 PF13041.6 EGB06011.1 - 2.8e-17 62.7 0.0 1.9e-09 37.6 0.0 4.4 3 1 1 4 4 4 2 PPR repeat family PPR PF01535.20 EGB06011.1 - 1.9e-12 46.5 3.0 4.8e-05 23.3 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 EGB06011.1 - 1.9e-10 40.2 0.1 0.00026 20.6 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EGB06011.1 - 2.4e-10 40.1 2.9 1.4e-06 27.9 0.2 5.1 3 1 1 5 5 5 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGB06011.1 - 3.3e-09 36.7 0.0 2.7e-05 24.1 0.0 4.4 4 1 0 4 4 4 1 Pentatricopeptide repeat domain TPR_6 PF13174.6 EGB06011.1 - 4.9e-05 23.7 4.5 0.014 16.0 0.1 6.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06011.1 - 0.00045 20.1 0.1 0.00045 20.1 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06011.1 - 0.0049 16.6 0.0 0.042 13.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06011.1 - 0.0084 16.3 0.4 0.23 11.8 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06011.1 - 0.014 16.2 0.3 0.014 16.2 0.3 15.7 12 3 6 18 18 15 0 Tetratricopeptide repeat Sel1 PF08238.12 EGB06011.1 - 0.014 16.0 0.9 3.1 8.6 0.1 3.2 2 0 0 2 2 2 0 Sel1 repeat TPR_7 PF13176.6 EGB06011.1 - 0.16 12.1 1.0 2.4 8.4 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF563 PF04577.14 EGB06013.1 - 3.3e-20 73.1 0.0 6.4e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Sulfotransfer_2 PF03567.14 EGB06013.1 - 0.0014 18.6 0.0 0.0037 17.2 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Xan_ur_permease PF00860.20 EGB06014.1 - 5.6e-60 203.1 20.2 4e-58 197.0 20.2 2.1 1 1 0 1 1 1 1 Permease family HSP70 PF00012.20 EGB06016.1 - 6.8e-75 252.4 2.9 6.8e-75 252.4 2.9 2.4 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGB06016.1 - 0.0019 17.1 0.7 0.0072 15.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FHA PF00498.26 EGB06017.1 - 5.4e-06 26.7 0.1 8.8e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 FHA domain adh_short PF00106.25 EGB06017.1 - 0.0001 21.9 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase WD40 PF00400.32 EGB06019.1 - 9.5e-53 175.0 27.5 4.6e-11 43.1 0.6 6.4 7 0 0 7 7 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06019.1 - 5.4e-16 58.7 3.3 0.0078 16.5 0.1 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB06019.1 - 3e-13 49.3 5.5 0.026 13.2 0.1 5.9 3 2 3 6 6 6 5 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGB06019.1 - 5.4e-06 26.2 16.4 0.0077 15.8 7.2 3.0 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.16 EGB06019.1 - 6.2e-06 25.0 2.7 0.00021 20.0 0.2 2.5 1 1 2 3 3 3 3 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 EGB06019.1 - 3.1e-05 23.1 17.5 0.1 11.5 0.5 5.3 3 2 2 6 6 6 2 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 EGB06019.1 - 0.00022 21.0 0.0 51 4.1 0.0 5.4 6 0 0 6 6 5 0 PQQ enzyme repeat eIF2A PF08662.11 EGB06019.1 - 0.00097 19.1 0.0 0.044 13.7 0.0 2.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Surfac_D-trimer PF09006.11 EGB06019.1 - 0.0015 18.4 2.1 83 3.2 0.0 5.1 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation PQQ_3 PF13570.6 EGB06019.1 - 0.0025 18.2 13.2 17 6.0 0.0 5.3 5 0 0 5 5 5 0 PQQ-like domain DUF1652 PF07865.11 EGB06019.1 - 0.0098 15.7 0.3 1.6e+02 2.2 0.0 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF1652) DHFR_2 PF06442.11 EGB06019.1 - 0.021 14.7 0.3 2.5 8.0 0.1 3.8 3 2 0 3 3 3 0 R67 dihydrofolate reductase DUF5570 PF17731.1 EGB06019.1 - 0.025 14.7 13.7 0.74 9.9 0.7 4.0 1 1 4 5 5 5 0 Family of unknown function (DUF5570) Prot_ATP_ID_OB PF16450.5 EGB06019.1 - 0.031 14.2 4.2 40 4.3 0.0 4.4 4 1 0 4 4 4 0 Proteasomal ATPase OB C-terminal domain WD40_like PF17005.5 EGB06019.1 - 0.073 12.4 0.0 13 5.0 0.0 3.1 1 1 3 4 4 4 0 WD40-like domain DUF333 PF03891.15 EGB06019.1 - 0.088 13.0 0.0 37 4.6 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF333) Frtz PF11768.8 EGB06019.1 - 0.096 11.0 0.0 1.1 7.5 0.0 2.3 1 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz NHL PF01436.21 EGB06019.1 - 0.32 11.1 9.7 1.1e+02 3.1 0.1 5.3 5 0 0 5 5 5 0 NHL repeat Ribosomal_S17 PF00366.20 EGB06019.1 - 1.6 8.9 9.4 41 4.4 0.1 4.1 4 0 0 4 4 4 0 Ribosomal protein S17 AvrPtoB_bdg PF16847.5 EGB06020.1 - 0.17 12.3 0.0 1.9 9.0 0.0 2.5 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain aGPT-Pplase1 PF18723.1 EGB06023.1 - 1.9e-49 168.6 0.0 6.9e-49 166.8 0.0 1.8 1 1 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 PHD PF00628.29 EGB06023.1 - 3.7e-12 46.0 2.5 7.9e-12 44.9 2.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGB06023.1 - 0.013 15.0 0.1 0.013 15.0 0.1 2.5 3 0 0 3 3 3 0 PHD-finger zf-RING_4 PF14570.6 EGB06023.1 - 3.9 7.3 10.6 0.65 9.8 5.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 EGB06023.1 - 4.6 7.3 10.1 0.35 10.8 3.3 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 HD_4 PF13328.6 EGB06026.1 - 3.5e-48 163.3 0.6 9.6e-48 161.9 0.6 1.8 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 EGB06026.1 - 1.3e-23 83.5 0.0 3e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 EGB06026.1 - 1.1e-18 67.1 0.0 2.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain HD PF01966.22 EGB06026.1 - 1.2e-07 31.9 0.1 3.6e-07 30.4 0.1 1.9 1 0 0 1 1 1 1 HD domain Ub-Mut7C PF14451.6 EGB06026.1 - 0.0056 16.5 0.0 0.02 14.7 0.0 2.0 1 0 0 1 1 1 1 Mut7-C ubiquitin Arm PF00514.23 EGB06027.1 - 9.4e-23 79.5 1.2 1.2e-07 31.5 0.0 3.0 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGB06027.1 - 5.3e-11 41.8 0.6 0.00099 19.2 0.0 3.0 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 EGB06027.1 - 2.2e-09 37.6 3.9 7e-09 36.0 3.3 2.0 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 EGB06027.1 - 2.1e-08 34.5 1.2 0.0014 19.1 0.1 2.9 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 EGB06027.1 - 0.0023 18.0 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 EGB06027.1 - 0.029 13.8 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like HEAT_PBS PF03130.16 EGB06027.1 - 2.5 9.0 10.0 42 5.2 1.0 3.9 3 2 0 3 3 3 0 PBS lyase HEAT-like repeat Glycos_transf_1 PF00534.20 EGB06028.1 - 3e-40 137.5 0.0 4.4e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGB06028.1 - 8.2e-22 78.1 0.1 1.4e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGB06028.1 - 2e-14 53.9 1.0 1.5e-13 51.1 0.8 2.2 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGB06028.1 - 2.4e-11 44.3 5.9 2.4e-11 44.3 5.9 2.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGB06028.1 - 4.1e-11 43.1 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 ICMT PF04140.14 EGB06029.1 - 5.7e-27 94.0 0.3 1.2e-26 92.9 0.3 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGB06029.1 - 2.4e-09 37.5 0.1 5.6e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EGB06029.1 - 4.1 7.4 7.8 1.1 9.2 3.2 2.1 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase BCS1_N PF08740.11 EGB06030.1 - 1.2e-31 110.1 0.0 1.8e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGB06030.1 - 3e-15 56.8 0.0 4.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGB06030.1 - 0.047 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB06030.1 - 0.084 13.2 0.6 0.27 11.6 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain HpcH_HpaI PF03328.14 EGB06031.1 - 1.3e-36 125.8 0.0 1.7e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ADH_zinc_N PF00107.26 EGB06031.1 - 0.027 14.5 0.2 0.39 10.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Exostosin PF03016.15 EGB06032.1 - 4.8e-06 26.0 0.0 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Exostosin family TPT PF03151.16 EGB06032.1 - 0.012 14.9 6.8 0.019 14.4 6.8 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family YXWGXW PF12779.7 EGB06032.1 - 0.4 10.9 2.6 0.96 9.7 2.6 1.6 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) ABC_tran PF00005.27 EGB06033.1 - 9.3e-48 162.2 0.0 3.8e-31 108.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGB06033.1 - 1.8e-42 145.9 0.6 2e-25 90.0 0.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGB06033.1 - 2.9e-09 36.7 3.4 0.0056 16.1 0.4 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB06033.1 - 1.2e-08 35.6 0.7 0.0008 19.8 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGB06033.1 - 6.4e-08 32.8 0.1 0.016 15.0 0.0 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGB06033.1 - 7.4e-05 22.8 0.3 0.4 10.8 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGB06033.1 - 0.00015 22.3 0.1 0.093 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGB06033.1 - 0.00054 20.3 2.7 0.24 11.7 0.2 2.9 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EGB06033.1 - 0.001 19.2 1.7 0.083 12.9 0.1 2.3 2 0 0 2 2 2 1 Dynamin family ABC_ATPase PF09818.9 EGB06033.1 - 0.0024 16.7 0.0 0.006 15.4 0.0 1.6 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 EGB06033.1 - 0.0059 16.3 2.4 0.98 9.2 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 EGB06033.1 - 0.0093 16.1 1.5 0.019 15.0 0.1 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 EGB06033.1 - 0.011 15.9 0.3 3.2 7.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGB06033.1 - 0.02 14.8 0.9 7 6.5 0.2 2.6 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 EGB06033.1 - 0.028 13.7 1.0 1.9 7.7 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EGB06033.1 - 0.039 13.7 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB06033.1 - 0.039 14.5 0.1 2.3 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGB06033.1 - 0.062 13.5 2.9 12 6.3 0.1 4.5 4 1 0 4 4 4 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EGB06033.1 - 0.094 12.4 3.7 2 8.1 0.4 3.0 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 EGB06033.1 - 0.11 12.2 0.2 11 5.7 0.1 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 EGB06033.1 - 0.11 11.5 1.0 2.1 7.3 0.2 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGB06033.1 - 0.13 11.6 1.4 9.5 5.5 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 EGB06033.1 - 0.16 11.4 0.8 0.82 9.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI dNK PF01712.19 EGB06033.1 - 0.16 11.8 0.0 19 5.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_10 PF12846.7 EGB06033.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.6 EGB06033.1 - 0.33 10.6 0.2 3.2 7.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF4239 PF14023.6 EGB06035.1 - 3e-17 63.1 0.6 1.2e-16 61.1 0.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4239) DUF4126 PF13548.6 EGB06035.1 - 0.011 15.4 2.5 0.035 13.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) Na_Ca_ex PF01699.24 EGB06036.1 - 1.4e-15 57.5 25.1 2.2e-08 34.2 6.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein NAC PF01849.18 EGB06037.1 - 4.8e-20 71.3 0.2 3.5e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 NAC domain Metallophos PF00149.28 EGB06038.1 - 4.7e-15 56.6 0.1 6.8e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RGS PF00615.19 EGB06039.1 - 2.2e-13 50.5 0.0 4.1e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ank_4 PF13637.6 EGB06039.1 - 2.6e-08 34.2 0.1 7.8e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB06039.1 - 3.4e-07 30.7 0.1 8.8e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DOT1 PF08123.13 EGB06039.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Ank_5 PF13857.6 EGB06039.1 - 3.4e-06 27.2 0.6 0.00015 22.0 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB06039.1 - 6.9e-05 22.9 0.1 0.22 12.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat BTB PF00651.31 EGB06039.1 - 9.1e-05 22.7 0.0 0.0028 17.9 0.0 2.8 3 0 0 3 3 3 1 BTB/POZ domain NAD_binding_8 PF13450.6 EGB06039.1 - 0.00054 20.1 1.6 0.0019 18.4 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain SET PF00856.28 EGB06039.1 - 0.0049 17.3 0.4 2.3 8.6 0.0 3.5 3 0 0 3 3 3 1 SET domain Acetyltransf_10 PF13673.7 EGB06039.1 - 0.044 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB06039.1 - 0.045 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank PF00023.30 EGB06039.1 - 0.09 13.3 0.5 0.55 10.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat fn3 PF00041.21 EGB06041.1 - 1e-193 628.3 110.9 1.6e-09 38.0 0.0 46.4 50 0 0 50 50 50 34 Fibronectin type III domain PA14 PF07691.12 EGB06041.1 - 1.1e-53 181.0 2.3 1.9e-20 73.2 0.2 5.9 6 0 0 6 6 6 3 PA14 domain Pur_ac_phosph_N PF16656.5 EGB06041.1 - 1.1e-26 93.2 99.1 0.0023 18.5 0.1 26.5 29 0 0 29 29 29 10 Purple acid Phosphatase, N-terminal domain Filamin PF00630.19 EGB06041.1 - 3.2e-23 82.5 0.0 8.1e-07 29.8 0.0 8.1 6 1 0 6 6 6 4 Filamin/ABP280 repeat DUF2369 PF10179.9 EGB06041.1 - 1.1e-11 44.9 0.1 8.7 6.8 0.0 10.1 11 0 0 11 11 11 2 Uncharacterised conserved protein (DUF2369) POTRA_1 PF08478.10 EGB06041.1 - 0.00021 21.5 0.1 1.3e+02 3.0 0.0 8.9 12 0 0 12 12 12 0 POTRA domain, FtsQ-type DUF3823_C PF18003.1 EGB06041.1 - 0.0015 19.3 10.1 0.97 10.2 0.1 8.9 10 0 0 10 10 10 1 Domain of unknown function (DUF3823_C) SusE PF14292.6 EGB06041.1 - 0.018 15.3 56.7 0.047 13.9 0.0 17.1 18 0 0 18 18 18 0 SusE outer membrane protein NAR2 PF16974.5 EGB06041.1 - 1.2 8.5 5.4 2 7.8 0.2 4.3 4 0 0 4 4 4 0 High-affinity nitrate transporter accessory Big_4 PF07532.11 EGB06041.1 - 8.5 6.2 32.3 1.3 8.8 0.1 8.2 8 0 0 8 8 8 0 Bacterial Ig-like domain (group 4) XPG_N PF00752.17 EGB06042.1 - 6.1e-21 74.8 0.0 1.1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGB06042.1 - 1.8e-17 63.5 0.1 4.7e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EGB06042.1 - 6e-06 25.9 0.2 1e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EGB06042.1 - 0.0064 17.1 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF3701 PF12482.8 EGB06042.1 - 0.033 14.2 0.0 0.099 12.7 0.0 1.8 1 0 0 1 1 1 0 Phage integrase protein DDHD PF02862.17 EGB06042.1 - 0.21 11.7 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 DDHD domain KH_1 PF00013.29 EGB06043.1 - 1.5e-11 43.9 0.8 2.4e-11 43.3 0.8 1.3 1 0 0 1 1 1 1 KH domain RNase_Zc3h12a PF11977.8 EGB06043.1 - 3.8e-10 39.8 0.0 7.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain VCBS PF13517.6 EGB06043.1 - 0.0056 17.3 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB06043.1 - 0.027 14.6 2.2 0.027 14.6 2.2 2.4 2 0 0 2 2 2 0 FG-GAP repeat KH_4 PF13083.6 EGB06043.1 - 0.032 14.1 0.2 0.075 12.9 0.2 1.6 1 0 0 1 1 1 0 KH domain KH_2 PF07650.17 EGB06043.1 - 0.05 13.4 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 KH domain Sulfatase PF00884.23 EGB06044.1 - 8.5e-44 150.2 0.1 9.8e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB06044.1 - 0.022 14.3 0.4 0.24 10.9 0.4 2.2 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGB06044.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Cullin_binding PF03556.15 EGB06045.1 - 1.2e-20 74.2 0.3 1.5e-20 73.8 0.3 1.1 1 0 0 1 1 1 1 Cullin binding adh_short_C2 PF13561.6 EGB06046.1 - 2.6e-53 181.0 5.2 3.5e-53 180.6 5.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB06046.1 - 9.4e-48 162.3 0.7 1.3e-47 161.8 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB06046.1 - 1.1e-11 45.0 2.6 1.8e-11 44.3 2.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGB06046.1 - 1.1e-05 25.4 5.7 1.7e-05 24.8 5.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGB06046.1 - 3.2e-05 23.5 0.9 9.5e-05 22.0 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGB06046.1 - 0.0041 16.3 3.8 0.0055 15.8 3.8 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Aldo_ket_red PF00248.21 EGB06047.1 - 6.9e-36 124.0 0.0 2.8e-35 122.0 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family 7TMR-DISMED2 PF07696.11 EGB06047.1 - 0.024 14.7 0.0 0.054 13.5 0.0 1.5 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 Sigma70_r2 PF04542.14 EGB06048.1 - 9e-21 73.4 0.1 9e-21 73.4 0.1 2.5 3 0 0 3 3 3 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EGB06048.1 - 1.4e-13 50.1 1.3 5.5e-13 48.2 0.5 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 EGB06048.1 - 1.5e-13 50.6 2.7 1.1e-09 38.2 0.4 3.7 3 0 0 3 3 3 2 Sigma-70 region 3 PgaD PF13994.6 EGB06048.1 - 0.0036 17.4 1.6 0.063 13.3 0.5 2.2 2 0 0 2 2 2 1 PgaD-like protein Sigma70_r1_2 PF00140.20 EGB06048.1 - 0.0058 16.6 0.9 0.015 15.3 0.9 1.8 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 TerB_C PF15615.6 EGB06048.1 - 0.18 12.1 5.1 2.6 8.3 0.4 2.2 2 0 0 2 2 2 0 TerB-C domain Aminotran_3 PF00202.21 EGB06049.1 - 2.2e-99 332.9 0.0 2.7e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EGB06049.1 - 8.5e-06 25.2 0.0 2.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGB06049.1 - 0.0097 15.1 0.0 0.018 14.2 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Myb_DNA-binding PF00249.31 EGB06050.1 - 2.2e-26 91.8 1.9 5.8e-14 52.0 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB06050.1 - 3.3e-20 72.1 0.1 2.8e-12 46.7 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EGB06050.1 - 0.00035 20.6 2.5 0.00084 19.4 0.2 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGB06050.1 - 0.0024 18.2 1.7 0.026 14.9 0.2 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGB06050.1 - 0.036 14.4 0.1 2.6 8.4 0.0 2.2 1 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3693 PF12472.8 EGB06050.1 - 0.073 12.7 2.3 1.6 8.5 0.6 2.5 2 1 0 2 2 2 0 Phage related protein ANF_receptor PF01094.28 EGB06051.1 - 5.2e-15 55.4 0.1 1e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region Thioredoxin PF00085.20 EGB06051.1 - 2.5e-11 43.5 0.0 6.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Hpt PF01627.23 EGB06051.1 - 0.017 15.3 0.3 0.017 15.3 0.3 2.0 2 0 0 2 2 2 0 Hpt domain Thioredoxin_2 PF13098.6 EGB06051.1 - 0.054 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain zf-C3HC4_3 PF13920.6 EGB06052.1 - 1.1e-07 31.6 5.9 2.2e-07 30.6 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EGB06052.1 - 2.3e-07 30.8 0.0 8.7e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 EGB06052.1 - 2.5e-07 30.4 7.3 5.6e-07 29.3 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB06052.1 - 6.1e-07 29.7 8.3 1.7e-06 28.2 8.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGB06052.1 - 1.4e-06 28.1 5.8 3e-06 27.0 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB06052.1 - 4.8e-06 26.3 5.6 9.8e-06 25.3 5.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGB06052.1 - 6.8e-06 25.9 5.6 1.3e-05 25.0 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB06052.1 - 8.5e-06 25.7 3.5 2.4e-05 24.3 3.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGB06052.1 - 0.00064 20.0 6.6 0.0015 18.7 6.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGB06052.1 - 0.0015 18.6 6.8 0.0032 17.6 6.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 EGB06052.1 - 0.055 13.6 2.0 0.18 12.0 0.8 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 EGB06052.1 - 0.4 10.8 2.5 0.89 9.7 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Siva PF05458.12 EGB06052.1 - 0.55 9.9 2.9 1 9.0 2.9 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_4 PF14570.6 EGB06052.1 - 0.82 9.5 6.2 2 8.3 6.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGB06052.1 - 0.94 9.2 7.9 2 8.1 7.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PAP_fibrillin PF04755.12 EGB06053.1 - 1.1e-05 25.4 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin Thioredoxin_6 PF13848.6 EGB06054.1 - 6.4e-23 81.6 1.1 4.7e-20 72.3 1.1 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 EGB06054.1 - 2.2e-22 79.0 0.0 6.2e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGB06054.1 - 0.0024 17.8 0.1 0.0076 16.2 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EGB06054.1 - 0.0057 17.1 0.1 0.031 14.7 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGB06054.1 - 0.028 14.6 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 EGB06054.1 - 0.033 14.5 0.0 0.13 12.6 0.0 2.1 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 EGB06054.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Redoxin GRP PF07172.11 EGB06054.1 - 3.9 8.2 23.3 8.5 7.1 23.3 1.6 1 0 0 1 1 1 0 Glycine rich protein family DUF308 PF03729.13 EGB06055.1 - 0.1 13.0 0.2 0.21 11.9 0.2 1.4 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) BBL5 PF07289.11 EGB06056.1 - 3.6e-145 483.2 0.0 4.1e-145 483.0 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein bPH_3 PF14470.6 EGB06056.1 - 4.6e-06 26.9 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 2 Bacterial PH domain Vps36_ESCRT-II PF11605.8 EGB06056.1 - 4.8e-06 26.7 0.1 0.0016 18.6 0.1 2.5 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.13 EGB06056.1 - 0.0001 22.4 0.0 0.3 11.2 0.0 2.5 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling PH_TFIIH PF08567.11 EGB06056.1 - 0.00056 20.2 0.0 0.23 11.8 0.0 2.4 2 0 0 2 2 2 2 TFIIH p62 subunit, N-terminal domain SBD_N PF07005.11 EGB06058.1 - 1e-50 172.6 1.6 1e-50 172.6 1.6 1.7 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 EGB06058.1 - 4.1e-35 121.8 2.1 4.1e-35 121.8 2.1 2.4 3 0 0 3 3 3 1 Nucleotide-binding C-terminal domain NAD_binding_11 PF14833.6 EGB06058.1 - 0.00039 20.6 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F_bP_aldolase PF01116.20 EGB06059.1 - 5.4e-66 222.9 0.2 6e-66 222.8 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ras PF00071.22 EGB06060.1 - 1.5e-63 213.3 0.2 1.7e-63 213.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB06060.1 - 5.2e-36 123.5 0.1 8e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB06060.1 - 3.3e-16 59.2 0.0 4.1e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB06060.1 - 8.5e-06 25.8 0.0 1.6e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB06060.1 - 3.2e-05 23.5 0.4 0.00014 21.5 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB06060.1 - 0.00012 22.0 0.1 0.26 11.2 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGB06060.1 - 0.00025 20.5 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGB06060.1 - 0.00092 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGB06060.1 - 0.02 15.2 0.0 0.03 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain CENP-M PF11111.8 EGB06060.1 - 0.049 12.8 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_16 PF13191.6 EGB06060.1 - 0.097 13.0 0.0 0.1 12.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 EGB06060.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 EGB06060.1 - 0.099 12.6 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 EGB06060.1 - 0.15 11.6 0.0 1.5 8.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EGB06060.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Ank_5 PF13857.6 EGB06061.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ATP-synt_E PF05680.12 EGB06061.1 - 3.5 8.0 6.6 0.19 12.1 0.6 1.9 2 0 0 2 2 2 0 ATP synthase E chain SRP9-21 PF05486.12 EGB06062.1 - 1.4e-07 31.8 0.0 3.4e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF4547 PF15080.6 EGB06062.1 - 0.064 12.9 0.1 0.065 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) cNMP_binding PF00027.29 EGB06063.1 - 5.4e-11 42.4 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Methyltransf_32 PF13679.6 EGB06064.1 - 1.2e-09 38.4 0.3 7.7e-09 35.7 0.3 2.0 1 1 0 1 1 1 1 Methyltransferase domain Biotin_lipoyl PF00364.22 EGB06065.1 - 6.2e-19 67.6 2.6 6.9e-19 67.5 2.6 1.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGB06065.1 - 1.9e-05 24.4 0.8 0.01 15.7 0.0 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EGB06065.1 - 0.0031 18.2 2.4 0.26 12.0 0.0 2.0 1 1 1 2 2 2 2 HlyD family secretion protein QRPTase_N PF02749.16 EGB06065.1 - 0.067 13.2 0.3 0.89 9.7 0.0 2.1 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Utp21 PF04192.12 EGB06066.1 - 3e-26 92.4 0.0 4.6e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EGB06066.1 - 1.2e-08 35.4 2.8 0.17 12.8 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06066.1 - 0.00017 21.8 0.0 6.2 7.2 0.0 4.7 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 EGB06066.1 - 0.063 11.9 0.0 0.18 10.3 0.0 1.6 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Helicase_C PF00271.31 EGB06068.1 - 2.3e-09 37.5 0.0 2.9e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavodoxin_1 PF00258.25 EGB06069.1 - 7.3e-20 71.6 0.1 9.5e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGB06070.1 - 2e-05 25.2 0.0 3.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGB06070.1 - 0.00042 20.6 0.0 0.0011 19.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain PDZ_6 PF17820.1 EGB06071.1 - 0.009 15.8 0.7 0.021 14.7 0.7 1.6 1 0 0 1 1 1 1 PDZ domain GAF_2 PF13185.6 EGB06071.1 - 0.22 11.8 1.7 0.48 10.7 0.3 2.2 3 0 0 3 3 3 0 GAF domain Prenyltrans PF00432.21 EGB06072.1 - 1.6e-56 187.6 30.1 1.8e-12 46.8 0.6 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGB06072.1 - 1e-06 28.1 0.9 0.00052 19.2 0.0 2.8 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain CAP59_mtransfer PF11735.8 EGB06073.1 - 0.00067 19.4 0.0 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_4 PF13704.6 EGB06073.1 - 0.016 15.7 0.0 0.23 12.0 0.0 2.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 NUDIX PF00293.28 EGB06073.1 - 0.036 14.1 0.0 0.14 12.2 0.0 2.0 1 0 0 1 1 1 0 NUDIX domain DUF5082 PF16888.5 EGB06073.1 - 0.2 12.0 0.6 0.45 10.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) MFS_1 PF07690.16 EGB06075.1 - 4.1e-18 65.4 37.6 6.5e-10 38.5 22.0 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 EGB06075.1 - 3.7e-06 26.2 11.0 0.025 13.6 7.7 2.3 2 0 0 2 2 2 2 PUCC protein MFS_2 PF13347.6 EGB06075.1 - 0.0011 17.7 7.5 0.006 15.2 0.0 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein Methyltransf_34 PF11312.8 EGB06075.1 - 0.12 11.7 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase MerR-DNA-bind PF09278.11 EGB06075.1 - 3.7 8.1 6.9 36 5.0 0.1 2.8 2 0 0 2 2 2 0 MerR, DNA binding Sugar_tr PF00083.24 EGB06075.1 - 4.3 6.1 10.8 0.066 12.1 2.2 2.0 2 0 0 2 2 2 0 Sugar (and other) transporter VCBS PF13517.6 EGB06076.1 - 6.3e-38 129.2 85.4 4.5e-10 40.0 7.9 8.2 5 3 4 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB06076.1 - 3.6e-28 97.3 98.4 0.00018 21.6 1.4 10.9 9 1 1 10 10 10 9 FG-GAP repeat BBS2_Mid PF14783.6 EGB06076.1 - 4.5e-10 39.5 3.0 13 5.8 0.0 9.0 10 0 0 10 10 10 2 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 EGB06076.1 - 0.062 12.3 23.1 0.82 8.6 0.0 7.9 10 0 0 10 10 10 0 Integrin-alpha FG-GAP repeat-containing protein 2 BBS1 PF14779.6 EGB06076.1 - 7.6 5.9 18.2 40 3.5 0.0 7.5 9 1 1 10 10 10 0 Ciliary BBSome complex subunit 1 ABC_tran PF00005.27 EGB06077.1 - 6.2e-06 26.8 0.0 8.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DHC_N1 PF08385.12 EGB06078.1 - 3.2e-165 551.0 16.8 3.2e-165 551.0 16.8 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EGB06078.1 - 2.4e-138 460.6 0.1 2.1e-136 454.2 0.0 3.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB06078.1 - 3.4e-109 365.6 11.5 3.4e-109 365.6 11.5 4.2 4 0 0 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGB06078.1 - 5.2e-85 284.9 0.0 3e-84 282.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGB06078.1 - 1.6e-81 273.9 0.0 7.2e-81 271.8 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGB06078.1 - 1.6e-72 243.2 0.2 7.1e-72 241.1 0.2 2.3 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGB06078.1 - 1.6e-57 194.0 0.5 1.2e-53 181.3 0.0 4.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB06078.1 - 1.7e-49 167.8 0.0 4.3e-49 166.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB06078.1 - 3.9e-35 120.5 0.0 2.2e-34 118.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGB06078.1 - 1.5e-34 119.6 10.0 3.3e-34 118.4 10.0 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EGB06078.1 - 6.6e-20 71.5 0.7 4.1e-19 68.9 0.0 2.9 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGB06078.1 - 4.5e-16 58.9 0.1 9.4e-15 54.6 0.0 3.2 2 1 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EGB06078.1 - 8.1e-12 45.3 0.1 0.00032 20.7 0.0 5.3 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB06078.1 - 2.1e-05 24.9 2.6 10 6.5 0.0 6.1 5 0 0 5 5 5 0 AAA ATPase domain AAA_22 PF13401.6 EGB06078.1 - 0.00012 22.3 4.4 11 6.3 0.1 5.4 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EGB06078.1 - 0.00043 20.8 0.3 1.2 9.6 0.0 3.6 3 0 0 3 3 2 1 ABC transporter Activator-TraM PF11657.8 EGB06078.1 - 0.021 14.7 0.5 0.068 13.0 0.5 1.8 1 0 0 1 1 1 0 Transcriptional activator TraM AAA PF00004.29 EGB06078.1 - 0.029 14.8 6.0 0.51 10.8 0.0 4.7 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) Exonuc_VII_S PF02609.16 EGB06078.1 - 0.28 11.3 2.7 1.7 8.8 1.4 3.2 2 0 0 2 2 2 0 Exonuclease VII small subunit AAA_18 PF13238.6 EGB06078.1 - 0.73 10.4 6.3 5.3 7.6 0.0 4.7 5 0 0 5 5 3 0 AAA domain BST2 PF16716.5 EGB06078.1 - 0.86 10.2 8.5 0.85 10.2 3.7 3.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Sel1 PF08238.12 EGB06079.1 - 2.4e-24 85.2 15.7 2.9e-08 34.1 0.2 4.6 4 1 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB06079.1 - 0.0022 18.6 14.3 0.32 11.7 8.8 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 EGB06079.1 - 0.0023 17.9 4.1 0.0043 17.1 0.3 2.7 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EGB06079.1 - 0.0047 17.2 9.8 0.09 13.1 2.2 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB06079.1 - 0.0085 16.4 0.5 11 6.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2514 PF10721.9 EGB06079.1 - 0.011 15.8 0.6 0.013 15.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TPR_10 PF13374.6 EGB06079.1 - 0.11 12.4 13.4 1.4 8.9 0.5 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06079.1 - 0.16 12.3 12.7 0.25 11.7 0.5 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06079.1 - 0.17 12.1 21.3 0.1 12.7 2.5 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat VIT PF08487.10 EGB06079.1 - 0.24 11.6 1.9 5.5 7.3 0.0 2.7 2 1 1 3 3 3 0 Vault protein inter-alpha-trypsin domain TPR_6 PF13174.6 EGB06079.1 - 0.54 11.0 10.1 8 7.3 1.8 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EGB06080.1 - 3.7e-38 131.4 0.0 5.6e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_4 PF12146.8 EGB06081.1 - 1.5e-12 47.3 0.0 4.4e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB06081.1 - 1e-06 28.6 0.0 1.9e-05 24.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB06081.1 - 6.9e-05 23.6 2.2 0.00012 22.8 1.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGB06081.1 - 0.00094 18.7 0.1 0.016 14.7 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EGB06081.1 - 0.0022 17.6 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Ndr PF03096.14 EGB06081.1 - 0.004 15.9 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S15 PF02129.18 EGB06081.1 - 0.0086 15.7 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EGB06081.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EGB06081.1 - 0.14 11.9 0.0 3.6 7.3 0.0 2.3 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 EGB06081.1 - 0.19 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase UPF0227 PF05728.12 EGB06081.1 - 0.2 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Sel1 PF08238.12 EGB06082.1 - 1.6e-33 114.4 31.7 7.5e-07 29.6 0.2 8.6 8 1 0 8 8 8 8 Sel1 repeat Flu_M1_C PF08289.11 EGB06082.1 - 0.0001 22.4 0.0 0.9 9.8 0.0 2.6 3 0 0 3 3 3 2 Influenza Matrix protein (M1) C-terminal domain B12-binding_2 PF02607.17 EGB06082.1 - 0.016 15.7 0.5 5.7 7.5 0.0 3.1 2 2 1 3 3 3 0 B12 binding domain HU-CCDC81_bac_2 PF18175.1 EGB06082.1 - 0.024 14.5 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 TPR_16 PF13432.6 EGB06082.1 - 0.046 14.4 5.5 0.046 14.4 5.5 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06082.1 - 0.056 13.7 20.6 0.58 10.5 1.7 5.8 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB06082.1 - 0.063 13.7 0.5 39 4.9 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3228 PF11539.8 EGB06082.1 - 0.064 12.8 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) AAA_lid_10 PF17872.1 EGB06082.1 - 0.099 12.8 0.0 24 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA lid domain TPR_8 PF13181.6 EGB06082.1 - 0.1 12.9 2.7 20 5.7 0.0 3.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EGB06083.1 - 7.7e-47 159.9 0.0 9.1e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06083.1 - 2.8e-30 105.5 0.0 3.3e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB06083.1 - 6.3e-05 22.4 0.2 8.7e-05 22.0 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB06083.1 - 0.0013 18.7 0.8 0.1 12.5 0.5 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EGB06083.1 - 0.0026 17.4 0.0 1 9.0 0.0 2.1 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 TFIIF_beta PF02270.15 EGB06083.1 - 0.077 13.1 0.0 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain Sel1 PF08238.12 EGB06084.1 - 1.5e-44 149.4 36.0 4.1e-08 33.6 0.1 9.9 9 2 0 9 9 9 8 Sel1 repeat TPR_12 PF13424.6 EGB06084.1 - 6.2e-05 23.2 28.7 0.35 11.2 1.3 7.0 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGB06084.1 - 0.00012 22.6 34.8 0.071 13.8 6.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat Rubrerythrin PF02915.17 EGB06084.1 - 0.00031 21.1 3.7 0.17 12.3 0.2 2.7 2 1 0 3 3 3 2 Rubrerythrin B12-binding_2 PF02607.17 EGB06084.1 - 0.00098 19.5 1.8 6.2 7.3 0.0 3.8 3 2 0 3 3 3 1 B12 binding domain TPR_17 PF13431.6 EGB06084.1 - 0.0042 17.4 4.6 47 4.7 0.0 6.1 6 1 1 7 7 6 0 Tetratricopeptide repeat HEXIM PF15313.6 EGB06084.1 - 0.0044 17.2 0.1 5.6 7.1 0.0 2.9 3 0 0 3 3 3 1 Hexamethylene bis-acetamide-inducible protein AAA_lid_10 PF17872.1 EGB06084.1 - 0.0066 16.6 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA lid domain Flu_M1_C PF08289.11 EGB06084.1 - 0.012 15.8 0.4 1 9.6 0.0 2.6 3 0 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain Ribonuc_red_lgC PF02867.15 EGB06084.1 - 0.015 13.9 1.7 0.19 10.2 0.1 2.3 2 1 0 2 2 2 0 Ribonucleotide reductase, barrel domain DUF3228 PF11539.8 EGB06084.1 - 0.1 12.1 0.2 18 4.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3228) PDDEXK_10 PF07788.11 EGB06084.1 - 0.26 11.2 1.0 18 5.4 0.0 3.1 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily TPR_8 PF13181.6 EGB06084.1 - 0.62 10.4 17.4 15 6.1 1.3 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat RHH_1 PF01402.21 EGB06084.1 - 0.83 9.7 3.4 20 5.3 0.1 3.5 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Phage_X PF05155.15 EGB06084.1 - 1.1 9.7 3.3 63 4.1 0.0 3.8 6 0 0 6 6 4 0 Phage X family TPR_6 PF13174.6 EGB06084.1 - 5.2 7.9 23.6 16 6.4 0.2 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat WD40 PF00400.32 EGB06085.1 - 8.3e-28 96.1 14.2 1.6e-08 35.1 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06085.1 - 5e-05 23.5 0.0 1.8 8.9 0.0 4.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1206 PF06724.11 EGB06085.1 - 0.14 12.3 0.9 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) F-box-like PF12937.7 EGB06085.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.8 1 1 0 1 1 1 0 F-box-like Abhydrolase_2 PF02230.16 EGB06086.1 - 3e-27 95.8 0.0 3.7e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EGB06086.1 - 7.1e-08 32.6 0.1 9.4e-05 22.4 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB06086.1 - 3.6e-07 29.7 0.2 0.031 13.6 0.0 2.9 2 1 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGB06086.1 - 4.5e-05 24.2 5.9 6.3e-05 23.7 5.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGB06086.1 - 6.9e-05 22.4 0.0 0.029 13.8 0.0 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 EGB06086.1 - 0.00029 20.5 0.4 0.00073 19.2 0.4 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Thioesterase PF00975.20 EGB06086.1 - 0.00042 20.5 0.6 0.00063 19.9 0.6 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EGB06086.1 - 0.011 15.3 0.3 0.035 13.8 0.3 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EGB06086.1 - 0.056 13.0 0.1 0.071 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2048 PF09752.9 EGB06086.1 - 0.11 11.5 0.0 0.59 9.2 0.1 1.9 2 0 0 2 2 2 0 Abhydrolase domain containing 18 cNMP_binding PF00027.29 EGB06087.1 - 4.4e-33 113.2 0.0 8.6e-18 64.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CENP-Q PF13094.6 EGB06088.1 - 0.0017 18.6 3.7 0.0035 17.5 3.7 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CENP-H PF05837.12 EGB06088.1 - 0.024 15.0 4.3 0.027 14.9 3.3 1.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Macoilin PF09726.9 EGB06088.1 - 0.087 11.4 1.6 0.11 11.0 1.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF3818 PF12825.7 EGB06088.1 - 0.39 9.7 1.0 0.57 9.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) PAH PF02671.21 EGB06089.1 - 6e-16 58.3 0.0 9.3e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat ACT PF01842.25 EGB06089.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 ACT domain PAH PF02671.21 EGB06090.1 - 2.4e-19 69.2 1.6 3.3e-19 68.8 1.6 1.2 1 0 0 1 1 1 1 Paired amphipathic helix repeat Rx_N PF18052.1 EGB06090.1 - 0.01 16.1 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 Rx N-terminal domain CCM2_C PF16545.5 EGB06090.1 - 0.06 13.9 0.1 0.062 13.8 0.1 1.1 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology Glyco_hydro_99 PF16317.5 EGB06091.1 - 2.8e-99 332.5 0.0 3.2e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 EGB06091.1 - 0.00036 20.1 0.0 0.0007 19.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase WbsX DUF5010 PF16402.5 EGB06091.1 - 0.007 15.2 0.0 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5010) Glyco_hydro_71 PF03659.14 EGB06091.1 - 0.14 10.9 0.0 0.23 10.3 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 71 PTPLA PF04387.14 EGB06092.1 - 2.6e-37 128.1 7.7 5.5e-37 127.0 7.7 1.5 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CRAL_TRIO PF00650.20 EGB06093.1 - 5.1e-16 58.8 0.0 6.9e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Ribosomal_L10 PF00466.20 EGB06096.1 - 1e-22 80.1 0.0 1.7e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGB06096.1 - 7.6e-20 70.7 0.1 2e-19 69.3 0.1 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EGB06096.1 - 0.0018 18.8 0.1 0.0072 16.9 0.0 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein bZIP_1 PF00170.21 EGB06096.1 - 0.29 11.3 0.6 9.2 6.4 0.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor Tctex-1 PF03645.13 EGB06097.1 - 6.6e-23 80.9 0.1 7.5e-23 80.7 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Ank_5 PF13857.6 EGB06098.1 - 7.7e-22 77.1 1.1 6.6e-11 42.2 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB06098.1 - 9.1e-20 70.2 0.7 4.9e-07 29.9 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGB06098.1 - 5.1e-19 68.4 0.4 7.2e-07 29.7 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB06098.1 - 1.2e-16 61.1 0.0 7.6e-10 39.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB06098.1 - 1.7e-12 46.4 0.8 0.00052 20.3 0.1 3.9 3 1 0 3 3 3 3 Ankyrin repeat CPP1-like PF11833.8 EGB06099.1 - 3.4e-09 36.6 0.1 2.8e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like cNMP_binding PF00027.29 EGB06100.1 - 8.4e-19 67.4 0.0 9e-19 67.3 0.0 1.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HlyE PF06109.13 EGB06100.1 - 0.017 14.5 0.0 0.02 14.2 0.0 1.0 1 0 0 1 1 1 0 Haemolysin E (HlyE) Dynamin_N PF00350.23 EGB06101.1 - 6.8e-28 97.8 0.0 7.7e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB06101.1 - 8.1e-08 32.3 0.1 2.1e-07 31.0 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB06101.1 - 0.00031 20.3 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGB06101.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 EGB06101.1 - 0.011 15.9 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EGB06101.1 - 0.013 16.0 0.1 0.02 15.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB06101.1 - 0.033 14.6 0.0 0.044 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EGB06101.1 - 0.049 13.3 0.0 0.095 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGB06101.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sulfotransfer_3 PF13469.6 EGB06103.1 - 0.079 13.3 0.1 4.4 7.6 0.0 2.4 1 1 0 2 2 2 0 Sulfotransferase family DUF3040 PF11239.8 EGB06103.1 - 3.5 8.0 5.8 41 4.5 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Semialdhyde_dh PF01118.24 EGB06105.1 - 1.4e-13 51.3 0.0 2.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 EGB06105.1 - 7.8e-13 48.9 0.1 2.2e-12 47.4 0.1 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Gp_dh_C PF02800.20 EGB06105.1 - 4.4e-05 23.1 0.0 0.00015 21.3 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain E1-E2_ATPase PF00122.20 EGB06106.1 - 7.4e-36 123.4 4.4 7.4e-36 123.4 4.4 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGB06106.1 - 7.5e-19 68.8 3.7 2.3e-18 67.3 3.7 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB06106.1 - 0.0003 21.3 0.8 0.0011 19.5 0.8 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGB06106.1 - 0.0042 17.5 2.8 0.0053 17.2 1.1 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGB06106.1 - 0.023 14.4 0.7 0.035 13.8 0.7 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rdx PF10262.9 EGB06107.1 - 6.7e-12 45.4 0.1 8.1e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 Rdx family Mpv17_PMP22 PF04117.12 EGB06108.1 - 3.9e-17 62.2 0.4 3.9e-17 62.2 0.4 1.7 1 1 1 2 2 2 1 Mpv17 / PMP22 family Kinesin PF00225.23 EGB06109.1 - 1.5e-90 303.5 0.0 1.7e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB06109.1 - 4.6e-25 88.3 0.0 6.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding DUF2347 PF09804.9 EGB06110.1 - 1e-37 130.3 0.0 1.1e-35 123.6 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 EGB06110.1 - 3.2e-07 29.4 0.0 0.015 14.0 0.0 2.7 2 1 0 3 3 3 2 Transport protein Avl9 SPA PF08616.10 EGB06110.1 - 2.4e-05 24.3 0.0 3.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Stabilization of polarity axis HTH_31 PF13560.6 EGB06110.1 - 2.4 8.6 11.5 0.44 10.9 4.7 3.3 2 2 0 2 2 2 0 Helix-turn-helix domain E1-E2_ATPase PF00122.20 EGB06111.1 - 3e-43 147.4 4.8 1.1e-42 145.6 4.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGB06111.1 - 8.1e-19 68.7 2.1 2.1e-18 67.4 1.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGB06111.1 - 0.0039 17.0 0.9 0.0057 16.4 0.3 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LRR_8 PF13855.6 EGB06112.1 - 1.5e-10 40.7 0.5 3.1e-05 23.7 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeat RNase_T PF00929.24 EGB06112.1 - 2.4e-09 38.0 0.0 3.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Exonuclease LRR_4 PF12799.7 EGB06112.1 - 2.2e-08 34.2 0.0 0.0019 18.5 0.1 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) WW PF00397.26 EGB06112.1 - 6.3e-08 32.6 7.4 1.5e-07 31.4 7.4 1.6 1 0 0 1 1 1 1 WW domain LRR_1 PF00560.33 EGB06112.1 - 0.0044 17.4 1.6 27 5.8 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat HHH PF00633.23 EGB06112.1 - 0.0054 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF5051 PF16473.5 EGB06112.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like DUF2052 PF09747.9 EGB06112.1 - 0.1 12.7 6.2 0.23 11.5 6.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) LRR_6 PF13516.6 EGB06112.1 - 0.13 12.3 1.9 72 3.8 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeat DNA_pol_phi PF04931.13 EGB06112.1 - 0.41 8.7 3.9 0.58 8.2 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 EGB06114.1 - 5.9e-59 199.6 0.0 7.2e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06114.1 - 2.4e-33 115.5 0.0 3e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB06114.1 - 9.9e-06 25.1 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB06114.1 - 2.1e-05 24.6 0.9 6.2e-05 23.0 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB06114.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YfkB PF08756.10 EGB06114.1 - 0.2 11.5 0.0 0.83 9.4 0.0 1.9 2 0 0 2 2 2 0 YfkB-like domain PseudoU_synth_2 PF00849.22 EGB06115.1 - 5e-21 75.5 0.0 8.9e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase MMR_HSR1_Xtn PF16897.5 EGB06116.1 - 1.6e-35 121.3 0.3 3e-35 120.4 0.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGB06116.1 - 2.3e-20 72.8 0.0 4.7e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EGB06116.1 - 1.8e-18 66.3 0.0 3.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGB06116.1 - 5e-11 42.4 0.0 1.2e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGB06116.1 - 0.0021 17.6 0.1 0.029 13.9 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGB06116.1 - 0.011 15.8 0.1 5.6 7.0 0.0 2.5 1 1 1 2 2 2 0 Dynamin family MeaB PF03308.16 EGB06116.1 - 0.028 13.4 0.3 0.053 12.5 0.3 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EGB06116.1 - 0.074 12.9 0.3 5.7 6.8 0.1 3.0 2 1 1 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 EGB06116.1 - 0.11 13.0 0.1 0.25 11.9 0.1 1.6 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 EGB06116.1 - 0.12 12.6 0.1 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Tubulin PF00091.25 EGB06117.1 - 1e-67 228.2 0.0 1.7e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB06117.1 - 2e-40 137.9 0.1 3e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGB06117.1 - 0.00014 22.2 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGB06117.1 - 0.003 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGB06117.1 - 0.02 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Annexin PF00191.20 EGB06118.1 - 1.9e-60 200.8 0.2 2.8e-18 65.7 0.0 4.0 4 0 0 4 4 4 4 Annexin FeoB_Cyto PF17910.1 EGB06118.1 - 0.073 13.6 1.9 19 5.9 0.0 3.3 2 1 1 3 3 3 0 FeoB cytosolic helical domain TetR_C_31 PF17940.1 EGB06118.1 - 0.098 12.9 0.2 0.89 9.8 0.2 2.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ATP-synt_ab PF00006.25 EGB06119.1 - 1.3e-62 211.2 0.0 2.4e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGB06119.1 - 6.4e-20 71.5 1.2 1.7e-19 70.1 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.6 EGB06119.1 - 0.053 13.9 0.5 0.13 12.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGB06119.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EGB06119.1 - 0.12 11.5 0.5 0.24 10.6 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 EGB06119.1 - 0.13 11.4 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_M20 PF01546.28 EGB06120.1 - 1.8e-31 109.5 0.0 2.4e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGB06120.1 - 1.9e-11 43.8 0.0 6.4e-11 42.1 0.0 1.9 3 0 0 3 3 3 1 Peptidase dimerisation domain Herpes_capsid PF06112.11 EGB06121.1 - 1.3 9.1 9.7 0.57 10.2 1.4 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Peptidase_C97 PF05903.14 EGB06122.1 - 2.8e-19 69.4 0.0 3.9e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Pro_isomerase PF00160.21 EGB06123.1 - 2.4e-42 144.9 0.0 2.7e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VDE PF07137.11 EGB06124.1 - 2.9e-73 246.3 0.0 4.2e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 VDE lipocalin domain CSD PF00313.22 EGB06124.1 - 0.00013 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Lipocalin PF00061.23 EGB06124.1 - 0.037 14.2 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Rho_RNA_bind PF07497.12 EGB06124.1 - 0.21 11.5 0.1 0.52 10.2 0.1 1.6 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain TPR_1 PF00515.28 EGB06125.1 - 6.3e-34 114.4 17.0 2.5e-06 27.1 1.6 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06125.1 - 4.5e-31 104.4 33.9 5.2e-06 26.2 3.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGB06125.1 - 1.6e-25 88.5 11.9 1.6e-07 30.9 0.1 6.1 3 2 3 6 6 6 5 TPR repeat TPR_8 PF13181.6 EGB06125.1 - 3.7e-19 67.3 8.9 0.0021 18.1 0.3 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGB06125.1 - 5.5e-19 67.1 13.1 0.0024 18.1 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGB06125.1 - 1e-15 57.6 32.6 5.2e-07 29.7 2.5 5.9 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGB06125.1 - 3.8e-13 49.8 71.5 1.7e-06 28.6 7.0 7.7 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06125.1 - 5e-11 42.7 29.9 1.1e-06 28.8 5.2 5.9 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGB06125.1 - 8.6e-08 32.3 16.9 0.41 11.4 1.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB06125.1 - 6.4e-07 29.8 23.0 0.019 15.4 1.2 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06125.1 - 7.1e-05 22.6 18.3 1.2 9.4 0.6 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06125.1 - 7.4e-05 23.3 53.1 0.00015 22.3 3.6 7.6 5 2 3 8 8 6 5 Tetratricopeptide repeat DUF3856 PF12968.7 EGB06125.1 - 8.4e-05 22.7 1.5 0.7 10.0 0.0 4.3 4 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 EGB06125.1 - 0.00059 18.9 0.1 0.46 9.3 0.2 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 MIT PF04212.18 EGB06125.1 - 0.3 11.2 6.3 14 5.8 0.0 4.6 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EGB06125.1 - 0.38 11.5 0.2 0.38 11.5 0.2 9.3 11 0 0 11 11 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB06125.1 - 5.5 7.0 29.9 0.3 11.0 1.2 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Cob_adeno_trans PF01923.18 EGB06127.1 - 3.3e-39 134.7 0.0 4.6e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF5522 PF17653.1 EGB06127.1 - 1.7e-20 72.7 6.4 2.9e-20 72.0 6.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5522) DUF4112 PF13430.6 EGB06128.1 - 0.051 13.9 0.0 0.19 12.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) Armet PF10208.9 EGB06129.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding His_Phos_1 PF00300.22 EGB06130.1 - 8.1e-30 104.0 1.0 3.9e-28 98.5 1.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cyt-b5 PF00173.28 EGB06130.1 - 2.5e-09 37.2 0.0 6.4e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Hydrolase_4 PF12146.8 EGB06131.1 - 0.00015 21.1 0.1 0.00054 19.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB06131.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PI3_PI4_kinase PF00454.27 EGB06132.1 - 5.9e-46 157.3 0.0 7.8e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGB06132.1 - 4.1e-14 52.1 0.1 8.1e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 FATC domain Kinesin PF00225.23 EGB06133.1 - 4e-108 361.3 0.2 6e-108 360.7 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB06133.1 - 6.7e-26 91.0 0.0 1.7e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding FlxA PF14282.6 EGB06133.1 - 0.025 14.6 10.0 0.14 12.1 10.1 2.2 1 1 1 2 2 2 0 FlxA-like protein GHMP_kinases_C PF08544.13 EGB06133.1 - 0.24 11.8 2.2 0.71 10.3 0.1 3.0 3 0 0 3 3 3 0 GHMP kinases C terminal RRM_1 PF00076.22 EGB06134.1 - 5.9e-09 35.6 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_21 PF13304.6 EGB06135.1 - 4.2e-12 46.5 0.1 3.4e-05 23.8 0.3 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EGB06135.1 - 5.6e-12 46.4 0.0 1.1e-11 45.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGB06135.1 - 5.1e-05 22.8 0.1 0.078 12.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGB06135.1 - 0.0015 19.1 0.1 0.0021 18.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB06135.1 - 0.0034 17.1 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB06135.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EGB06135.1 - 0.016 14.8 0.0 0.06 12.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGB06135.1 - 0.017 14.8 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGB06135.1 - 0.018 14.8 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EGB06135.1 - 0.025 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB06135.1 - 0.027 14.2 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGB06135.1 - 0.039 14.5 0.0 0.061 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EGB06135.1 - 0.046 13.6 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 EGB06135.1 - 0.052 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EGB06135.1 - 0.057 13.6 0.1 0.097 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EGB06135.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB06135.1 - 0.09 12.1 0.4 0.33 10.3 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EGB06135.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Roc PF08477.13 EGB06135.1 - 0.16 12.2 0.1 0.36 11.0 0.0 1.7 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EGB06135.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB06135.1 - 0.19 12.0 0.4 1.8 8.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB06135.1 - 0.2 11.6 0.3 0.47 10.4 0.3 1.6 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.8 EGB06135.1 - 0.25 8.8 0.1 0.34 8.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SH3_14 PF18343.1 EGB06137.1 - 7.2 6.7 5.6 5.5 7.1 0.1 3.4 4 0 0 4 4 4 0 Dda helicase SH3 domain Glucosamine_iso PF01182.20 EGB06138.1 - 1.4e-16 61.1 0.1 2.1e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Methyltransf_16 PF10294.9 EGB06139.1 - 5.7e-15 55.5 0.0 9.9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF3275 PF11679.8 EGB06139.1 - 4.8 7.1 6.2 32 4.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3275) Glyco_transf_25 PF01755.17 EGB06140.1 - 1.4e-15 57.7 0.0 2.4e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) CAP_N PF01213.19 EGB06140.1 - 2.7 7.4 6.8 4.1 6.8 6.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal H_PPase PF03030.16 EGB06142.1 - 1.4e-228 760.8 38.0 1.6e-228 760.6 38.0 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DnaJ PF00226.31 EGB06143.1 - 5.6e-28 96.9 4.8 7.2e-28 96.5 4.8 1.1 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGB06143.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 1 1 1 2 2 2 0 A repeated domain in UCH-protein AhpC-TSA_2 PF13911.6 EGB06145.1 - 8.5e-14 51.6 0.0 2.1e-12 47.1 0.0 2.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DJ-1_PfpI PF01965.24 EGB06146.1 - 8.7e-39 133.0 0.2 1e-38 132.8 0.2 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family FKBP_C PF00254.28 EGB06147.1 - 9.4e-13 48.3 0.0 1.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_hydro_47 PF01532.20 EGB06148.1 - 1.5e-42 146.1 0.0 1.6e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HSF_DNA-bind PF00447.17 EGB06149.1 - 3.4e-20 72.5 0.1 3.7e-20 72.3 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding FMO-like PF00743.19 EGB06150.1 - 1.1e-70 238.6 0.0 1.4e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGB06150.1 - 4.5e-21 75.4 0.1 1.3e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB06150.1 - 1.8e-14 53.7 0.0 4.3e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB06150.1 - 1e-12 47.9 3.3 1.1e-10 41.2 0.0 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGB06150.1 - 4.1e-06 26.6 1.3 0.24 11.0 0.7 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGB06150.1 - 2.2e-05 24.6 0.2 0.00027 21.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EGB06150.1 - 0.0018 18.7 0.1 0.45 11.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EGB06150.1 - 0.0043 16.2 0.2 0.021 13.9 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EGB06150.1 - 0.02 13.6 0.6 0.057 12.1 0.5 1.8 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 EGB06150.1 - 0.028 14.4 4.7 1.2 9.1 1.2 3.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EGB06150.1 - 0.042 13.2 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGB06150.1 - 0.06 12.6 2.1 0.6 9.3 0.7 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 EGB06150.1 - 0.19 10.9 0.4 0.41 9.8 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EGB06150.1 - 0.62 10.7 4.3 39 4.9 0.7 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sel1 PF08238.12 EGB06151.1 - 1.2e-40 137.0 39.2 2.3e-09 37.6 0.1 8.7 8 2 0 8 8 8 7 Sel1 repeat TPR_16 PF13432.6 EGB06151.1 - 5.9e-07 30.0 30.2 0.012 16.3 4.6 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 EGB06151.1 - 0.0037 17.6 5.5 0.07 13.5 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB06151.1 - 0.0055 17.0 3.7 1.8 9.1 0.4 4.6 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF410 PF04190.13 EGB06151.1 - 0.023 14.5 1.2 0.92 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF410) B12-binding_2 PF02607.17 EGB06151.1 - 0.12 12.8 2.1 28 5.3 0.1 3.3 2 1 1 3 3 3 0 B12 binding domain TPR_12 PF13424.6 EGB06151.1 - 0.16 12.3 0.4 0.16 12.3 0.4 6.0 3 3 4 7 7 7 0 Tetratricopeptide repeat TetR_C_11 PF16859.5 EGB06151.1 - 0.65 10.3 4.3 9.7 6.5 0.1 4.0 5 1 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain ANAPC3 PF12895.7 EGB06151.1 - 2.8 8.2 7.5 1.3 9.3 1.3 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PH PF00169.29 EGB06153.1 - 8.6e-07 29.4 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGB06153.1 - 9.1e-05 22.8 0.0 0.0002 21.7 0.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EGB06153.1 - 0.00014 22.0 0.1 0.0069 16.6 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain ABC_tran PF00005.27 EGB06154.1 - 1.5e-29 103.2 0.0 1.9e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGB06154.1 - 9.8e-08 31.7 0.0 0.00019 20.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGB06154.1 - 0.00071 19.8 1.9 0.012 15.8 1.9 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EGB06154.1 - 0.0047 16.7 0.8 1.7 8.3 0.3 2.1 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_29 PF13555.6 EGB06154.1 - 0.0055 16.4 0.3 0.014 15.1 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB06154.1 - 0.0064 16.3 0.3 0.036 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGB06154.1 - 0.012 15.9 0.1 0.048 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB06154.1 - 0.024 14.5 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EGB06154.1 - 0.13 12.3 0.1 0.78 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB06154.1 - 0.13 12.6 5.7 1.2 9.5 5.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain TPR_14 PF13428.6 EGB06155.1 - 0.15 13.0 0.1 0.15 13.0 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06155.1 - 0.61 10.3 0.1 0.61 10.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MARVEL PF01284.23 EGB06156.1 - 2.5e-06 27.6 3.0 5.4e-06 26.5 3.0 1.6 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 EGB06156.1 - 4.3e-05 23.3 11.6 5.9e-05 22.9 8.5 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF588) tRNA-synt_2 PF00152.20 EGB06157.1 - 4.5e-79 265.8 0.0 5.7e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGB06157.1 - 4.5e-11 42.6 0.0 9.5e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGB06157.1 - 4.9e-07 29.5 0.1 0.00087 18.8 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) EF-hand_1 PF00036.32 EGB06158.1 - 1.4e-06 27.4 5.7 0.014 14.9 0.9 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB06158.1 - 3.2e-05 23.5 4.9 0.007 16.2 0.5 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EGB06158.1 - 0.018 15.5 4.0 0.046 14.2 1.4 2.4 2 0 0 2 2 2 0 EF-hand domain pair REF PF05755.12 EGB06158.1 - 0.26 11.1 8.5 29 4.4 9.0 2.3 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) EF-hand_5 PF13202.6 EGB06158.1 - 0.43 10.2 5.0 1.9 8.1 0.4 2.6 2 0 0 2 2 2 0 EF hand NAM-associated PF14303.6 EGB06158.1 - 3.6 8.3 18.9 2.9 8.6 10.8 3.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain S10_plectin PF03501.15 EGB06159.1 - 9.7e-47 157.0 0.4 1.1e-46 156.8 0.4 1.0 1 0 0 1 1 1 1 Plectin/S10 domain RQC PF09382.10 EGB06159.1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.6 2 0 0 2 2 2 0 RQC domain Pox_vIL-18BP PF05566.12 EGB06159.1 - 0.14 12.3 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein Thiolase_N PF00108.23 EGB06160.1 - 1.8e-80 270.0 3.2 3.2e-80 269.2 3.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sulfotransfer_4 PF17784.1 EGB06160.1 - 7e-55 186.2 0.0 1.1e-54 185.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain AAA PF00004.29 EGB06160.1 - 6.6e-41 139.8 0.0 1.2e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thiolase_C PF02803.18 EGB06160.1 - 4.9e-36 123.1 3.8 1.6e-35 121.4 3.8 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain Lactamase_B_2 PF12706.7 EGB06160.1 - 3.8e-13 49.4 4.7 3.4e-07 30.0 0.2 3.3 2 1 0 2 2 2 2 Beta-lactamase superfamily domain AAA_lid_3 PF17862.1 EGB06160.1 - 1e-10 41.3 0.1 3.3e-10 39.6 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain Lactamase_B PF00753.27 EGB06160.1 - 8.7e-06 25.9 2.4 1.7e-05 24.9 0.3 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily AAA_5 PF07728.14 EGB06160.1 - 3.1e-05 24.0 0.0 0.0001 22.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB06160.1 - 0.00016 22.1 0.1 0.00064 20.2 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EGB06160.1 - 0.00025 20.9 0.1 0.00078 19.4 0.1 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EGB06160.1 - 0.00047 20.3 0.0 0.00086 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGB06160.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB06160.1 - 0.0015 18.8 0.0 0.039 14.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain ketoacyl-synt PF00109.26 EGB06160.1 - 0.0048 16.5 2.5 0.0048 16.5 2.5 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AAA_33 PF13671.6 EGB06160.1 - 0.0064 16.7 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGB06160.1 - 0.0096 15.2 0.0 0.024 13.8 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGB06160.1 - 0.015 15.1 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EGB06160.1 - 0.027 14.3 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGB06160.1 - 0.033 14.4 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB06160.1 - 0.037 13.4 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGB06160.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGB06160.1 - 0.074 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB06160.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EGB06160.1 - 0.16 11.8 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EGB06160.1 - 0.17 11.3 0.0 0.68 9.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 EGB06160.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EGB06160.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EGB06160.1 - 0.25 11.0 1.6 0.3 10.8 0.0 1.9 2 1 0 2 2 1 0 Sigma-54 interaction domain DnaJ PF00226.31 EGB06161.1 - 5.9e-20 71.2 0.0 6.5e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain Voltage_CLC PF00654.20 EGB06162.1 - 2.4e-75 254.0 26.8 2.4e-75 254.0 26.8 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGB06162.1 - 5.7e-07 29.9 0.0 0.00055 20.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain CBFB_NFYA PF02045.15 EGB06162.1 - 0.00014 22.4 1.9 0.00014 22.4 1.9 3.0 4 0 0 4 4 4 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DcpS_C PF11969.8 EGB06163.1 - 2e-16 60.5 0.0 3.4e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ERCC4 PF02732.15 EGB06164.1 - 1.3e-09 38.5 0.0 1.4e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 ERCC4 domain Mpv17_PMP22 PF04117.12 EGB06165.1 - 1.6e-16 60.3 0.0 9.3e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Aldose_epim PF01263.20 EGB06166.1 - 4.4e-33 114.9 0.0 4.9e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Cyclin_N PF00134.23 EGB06167.1 - 2e-23 82.5 0.1 2.9e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGB06167.1 - 0.074 13.1 0.6 0.16 12.1 0.1 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain TTL PF03133.15 EGB06168.1 - 1.5e-60 204.9 0.0 1.7e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB06168.1 - 5.8e-08 32.3 0.0 7.3e-06 25.4 0.0 2.4 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGB06168.1 - 0.0006 19.1 0.0 0.0028 16.9 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EGB06168.1 - 0.037 14.1 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain GSP_synth PF03738.14 EGB06168.1 - 0.038 13.2 0.0 0.3 10.2 0.0 2.2 1 1 0 2 2 2 0 Glutathionylspermidine synthase preATP-grasp Glyco_hydro_16 PF00722.21 EGB06169.1 - 7.8e-25 87.4 0.0 9.5e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGB06169.1 - 5.5e-07 28.4 0.0 0.00045 18.8 0.1 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Dev_Cell_Death PF10539.9 EGB06170.1 - 3.3e-08 33.5 0.0 5.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Development and cell death domain UQ_con PF00179.26 EGB06171.1 - 4e-40 136.7 0.0 4.5e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-MYND PF01753.18 EGB06172.1 - 1.2e-08 34.9 18.1 3.7e-08 33.3 18.1 2.0 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.6 EGB06172.1 - 0.0098 16.2 11.7 0.044 14.1 2.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat BolA PF01722.18 EGB06172.1 - 0.053 13.8 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 BolA-like protein Rtt106 PF08512.12 EGB06173.1 - 1.8e-23 82.8 0.0 3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like SSrecog PF03531.14 EGB06173.1 - 7.6e-20 70.6 0.0 1.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.19 EGB06173.1 - 1.3e-18 67.2 0.1 1.3e-18 67.2 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB06173.1 - 2.5e-14 53.6 0.1 7.5e-14 52.1 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain POB3_N PF17292.2 EGB06173.1 - 2.7e-09 37.3 0.1 8.8e-09 35.7 0.1 1.9 1 0 0 1 1 1 1 POB3-like N-terminal PH domain XRCC4 PF06632.12 EGB06173.1 - 0.13 11.0 8.8 0.23 10.2 8.8 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Glypican PF01153.19 EGB06173.1 - 3.2 6.5 4.9 4.8 5.9 4.9 1.2 1 0 0 1 1 1 0 Glypican APH PF01636.23 EGB06174.1 - 1.1e-18 68.0 8.4 1.1e-18 68.0 8.4 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGB06174.1 - 0.00034 20.2 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EGB06174.1 - 0.00058 19.2 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase RBFA PF02033.18 EGB06174.1 - 0.0027 18.1 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 Ribosome-binding factor A 2-Hacid_dh_C PF02826.19 EGB06175.1 - 3.6e-35 120.9 0.0 5.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGB06175.1 - 0.0015 17.8 0.0 0.003 16.9 0.0 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IlvN PF07991.12 EGB06175.1 - 0.06 12.9 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EGB06175.1 - 0.079 13.5 0.8 0.18 12.3 0.8 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.21 EGB06175.1 - 0.13 11.6 4.3 0.17 11.2 0.9 2.1 1 1 1 2 2 2 0 ThiF family Shikimate_DH PF01488.20 EGB06175.1 - 0.16 12.0 0.2 0.7 10.0 0.2 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 EGB06175.1 - 0.17 11.9 0.9 0.65 10.0 0.5 2.1 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 EGB06175.1 - 0.21 12.2 3.0 13 6.5 3.0 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AMP-binding_C PF13193.6 EGB06176.1 - 9.2e-20 71.4 0.1 1.3e-19 70.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EGB06176.1 - 2.3e-16 59.4 0.3 3.2e-16 59.0 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGB06177.1 - 1.1e-42 146.3 8.8 1.9e-42 145.6 8.8 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB06177.1 - 2.1e-31 108.4 0.0 3.5e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGB06177.1 - 0.0011 19.4 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension RRM_9 PF18444.1 EGB06177.1 - 0.026 14.4 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif ACP_syn_III PF08545.10 EGB06177.1 - 2 8.3 7.0 0.91 9.4 1.1 3.4 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Actin PF00022.19 EGB06178.1 - 8.5e-65 218.9 0.0 3.6e-32 111.5 0.0 3.0 1 1 1 3 3 3 3 Actin MreB_Mbl PF06723.13 EGB06178.1 - 3.8e-10 39.1 0.0 2.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Na_H_Exchanger PF00999.21 EGB06179.1 - 3.2e-42 144.7 31.9 4.3e-42 144.3 31.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GTP_EFTU PF00009.27 EGB06180.1 - 3.3e-32 111.6 3.1 1.4e-31 109.5 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGB06180.1 - 5.1e-18 65.1 0.0 1.5e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 EGB06180.1 - 1.8e-10 40.6 0.0 3.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EGB06180.1 - 4.1e-06 27.1 3.7 0.0067 16.8 0.1 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGB06180.1 - 8.2e-06 25.9 0.0 2.5e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB06180.1 - 0.0027 17.6 0.2 5.7 6.8 0.0 3.3 2 1 1 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 EGB06180.1 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EGB06180.1 - 0.14 12.5 0.1 1.4 9.2 0.1 2.6 1 1 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.23 EGB06181.1 - 3.2e-17 63.3 0.0 5.2e-17 62.7 0.0 1.3 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB06181.1 - 0.0034 16.2 0.2 0.0051 15.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C39_2 PF13529.6 EGB06181.1 - 0.0071 16.9 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase_C39 like family Cyto_heme_lyase PF01265.17 EGB06182.1 - 6.3e-29 101.5 6.5 2.1e-27 96.5 6.5 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF3768 PF12599.8 EGB06182.1 - 0.032 14.2 0.3 0.1 12.6 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3768) AAA PF00004.29 EGB06183.1 - 2.7e-19 69.9 0.0 4.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB06183.1 - 3.6e-05 24.2 2.3 0.0003 21.2 2.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EGB06183.1 - 0.00078 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGB06183.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGB06183.1 - 0.0033 17.7 1.0 0.2 11.9 0.2 2.4 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EGB06183.1 - 0.0035 16.7 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.17 EGB06183.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.6 EGB06183.1 - 0.0096 16.3 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGB06183.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EGB06183.1 - 0.017 14.7 1.0 0.063 12.8 0.2 2.1 1 1 2 3 3 3 0 AAA domain AAA_5 PF07728.14 EGB06183.1 - 0.019 15.0 0.1 0.35 10.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EGB06183.1 - 0.019 14.2 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 EGB06183.1 - 0.02 14.1 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 EGB06183.1 - 0.023 15.0 0.0 0.07 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGB06183.1 - 0.038 13.8 0.0 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGB06183.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 EGB06183.1 - 0.12 13.0 0.0 0.19 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGB06183.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EGB06183.1 - 0.16 11.8 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Hydin_ADK PF17213.3 EGB06183.1 - 0.18 12.1 0.1 0.34 11.2 0.1 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Acyl-CoA_dh_1 PF00441.24 EGB06184.1 - 2.3e-49 167.5 1.7 2.3e-49 167.5 1.7 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGB06184.1 - 7.1e-27 94.3 0.7 3.9e-26 91.9 0.5 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGB06184.1 - 8.5e-22 77.9 2.6 8.5e-22 77.9 2.6 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGB06184.1 - 1.2e-20 73.4 0.0 3.3e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ribosomal_L19e PF01280.20 EGB06185.1 - 3.3e-63 212.0 10.5 3.3e-63 212.0 10.5 1.3 2 0 0 2 2 2 1 Ribosomal protein L19e Sel1 PF08238.12 EGB06186.1 - 2.2e-11 44.1 1.6 5.9e-10 39.5 0.4 2.0 2 0 0 2 2 2 2 Sel1 repeat VPS13_C PF16909.5 EGB06188.1 - 1.7e-19 70.3 0.0 4.9e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal DWNN PF08783.11 EGB06189.1 - 9.6e-28 96.3 0.1 1.1e-27 96.1 0.1 1.0 1 0 0 1 1 1 1 DWNN domain DUF371 PF04027.13 EGB06189.1 - 0.078 12.9 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF371) Ras PF00071.22 EGB06190.1 - 4.8e-35 120.6 0.0 5.9e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB06190.1 - 7.6e-27 93.9 0.0 1.1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB06190.1 - 1.7e-09 37.4 0.0 2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB06190.1 - 0.00016 21.1 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB06190.1 - 0.00062 19.8 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGB06190.1 - 0.0053 16.0 0.1 1.3 8.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit IIGP PF05049.13 EGB06190.1 - 0.018 14.1 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EGB06190.1 - 0.14 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGB06190.1 - 0.17 11.7 0.0 0.52 10.0 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGB06190.1 - 0.17 11.8 0.0 1.3 8.9 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase Acyltransferase PF01553.21 EGB06191.1 - 9.6e-26 90.0 0.0 1.1e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase FKBP_C PF00254.28 EGB06192.1 - 3.8e-31 107.3 0.0 4.8e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WD40_3 PF15911.5 EGB06193.1 - 2.7e-21 75.3 0.0 2.3e-20 72.3 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06193.1 - 1e-11 45.0 0.0 0.079 13.3 0.0 4.7 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGB06193.1 - 2.4e-08 34.5 4.8 0.55 11.2 0.1 7.1 6 1 1 7 7 7 1 WD domain, G-beta repeat TPR_14 PF13428.6 EGB06193.1 - 6.6e-07 29.6 15.7 0.27 12.2 0.2 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat IKI3 PF04762.12 EGB06193.1 - 6.2e-06 24.5 0.0 0.13 10.3 0.0 3.8 4 0 0 4 4 4 2 IKI3 family Clathrin PF00637.20 EGB06193.1 - 4.5e-05 23.3 0.1 0.38 10.6 0.0 4.1 1 1 4 5 5 5 2 Region in Clathrin and VPS TPR_7 PF13176.6 EGB06193.1 - 8.5e-05 22.3 11.8 1.5 9.0 0.1 6.7 8 1 1 9 9 7 2 Tetratricopeptide repeat eIF2A PF08662.11 EGB06193.1 - 0.00075 19.4 0.0 0.071 13.0 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nic96 PF04097.14 EGB06193.1 - 0.0056 15.2 1.8 0.052 12.0 0.4 3.1 1 1 2 3 3 3 1 Nup93/Nic96 TPR_19 PF14559.6 EGB06193.1 - 0.015 15.8 12.0 5.7 7.5 0.1 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EGB06193.1 - 0.022 13.8 4.7 1 8.3 0.2 3.5 4 0 0 4 4 4 0 Coatomer WD associated region PALB2_WD40 PF16756.5 EGB06193.1 - 0.032 13.1 0.0 0.083 11.8 0.0 1.6 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SGL PF08450.12 EGB06193.1 - 0.07 12.7 0.1 1 8.9 0.0 2.8 3 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region TPR_4 PF07721.14 EGB06193.1 - 1.5 9.7 9.9 69 4.5 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06193.1 - 5.2 7.4 22.2 6.1 7.2 0.2 7.4 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06193.1 - 5.9 7.2 19.9 5 7.5 0.0 7.6 7 1 1 8 8 8 0 Tetratricopeptide repeat SNAP PF14938.6 EGB06193.1 - 6.4 6.1 10.8 12 5.2 6.8 2.9 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP Annexin PF00191.20 EGB06194.1 - 1.5e-53 178.7 0.0 3.7e-15 55.7 0.0 4.0 4 0 0 4 4 4 4 Annexin Peptidase_S10 PF00450.22 EGB06195.1 - 6.4e-65 220.2 0.0 5.4e-64 217.1 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase RraA-like PF03737.15 EGB06196.1 - 3.7e-27 95.3 0.0 7.2e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Aldolase/RraA FAST_1 PF06743.15 EGB06196.1 - 3.6e-12 46.0 0.0 0.98 9.4 0.0 8.9 6 2 5 11 11 11 5 FAST kinase-like protein, subdomain 1 RAP PF08373.10 EGB06196.1 - 3.6e-09 36.6 0.0 7.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 RAP domain DUF1601 PF07671.11 EGB06196.1 - 9.4e-06 25.4 21.7 1.8 8.5 0.1 10.3 12 0 0 12 12 12 3 Protein of unknown function (DUF1601) MTES_1575 PF18741.1 EGB06196.1 - 0.051 13.8 0.0 0.98 9.6 0.0 2.3 2 0 0 2 2 2 0 REase_MTES_1575 C2 PF00168.30 EGB06197.1 - 2.2e-19 69.6 0.0 4.3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 EGB06197.1 - 2.5e-17 63.1 0.0 3.2e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB06197.1 - 2.5e-16 58.2 2.4 0.0029 17.4 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGB06197.1 - 2.9e-16 57.7 8.5 9.4e-05 21.7 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGB06197.1 - 1.1e-11 43.6 11.5 0.0006 19.2 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB06197.1 - 1.1e-08 34.8 1.6 0.00061 19.6 0.1 4.1 4 1 1 5 5 5 1 EF-hand domain pair Abhydrolase_1 PF00561.20 EGB06197.1 - 4e-07 29.9 0.0 7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PRT_C PF08372.10 EGB06197.1 - 0.00021 21.1 1.0 0.21 11.4 0.1 2.6 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal Peptidase_S15 PF02129.18 EGB06197.1 - 0.00036 20.2 0.0 0.00081 19.1 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Reticulon PF02453.17 EGB06197.1 - 0.00043 20.3 2.7 0.28 11.2 0.5 2.4 2 0 0 2 2 2 2 Reticulon Hydrolase_4 PF12146.8 EGB06197.1 - 0.00081 18.7 0.0 0.0035 16.6 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Pex24p PF06398.11 EGB06197.1 - 0.0031 16.6 0.0 0.31 10.0 0.0 2.2 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin SPARC_Ca_bdg PF10591.9 EGB06197.1 - 0.015 15.6 0.0 19 5.6 0.0 3.7 3 1 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGB06197.1 - 0.025 14.4 1.8 22 5.0 0.4 3.7 3 0 0 3 3 3 0 EF hand DUF639 PF04842.12 EGB06197.1 - 0.064 12.7 1.0 1.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) PhoR PF11808.8 EGB06197.1 - 0.099 13.1 0.1 0.099 13.1 0.1 2.2 2 0 0 2 2 1 0 Phosphate regulon sensor protein PhoR Peptidase_S9 PF00326.21 EGB06197.1 - 0.56 9.7 1.8 2.4 7.6 0.1 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family PhyH PF05721.13 EGB06198.1 - 1.5e-09 38.4 0.0 9.1e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) LSM PF01423.22 EGB06200.1 - 5.2e-20 70.9 0.1 6.1e-20 70.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain HECT PF00632.25 EGB06201.1 - 2.9e-71 240.5 0.0 3.3e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L22 PF00237.19 EGB06202.1 - 6.3e-40 135.6 0.4 9.4e-40 135.0 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Enkurin PF13864.6 EGB06203.1 - 5.2e-23 81.3 7.1 8.2e-23 80.7 7.1 1.3 1 0 0 1 1 1 1 Calmodulin-binding Y_phosphatase3 PF13350.6 EGB06203.1 - 0.0085 16.1 1.2 0.049 13.6 0.1 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family JAKMIP_CC3 PF16034.5 EGB06203.1 - 0.011 15.7 3.1 0.013 15.4 3.1 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain NuA4 PF09340.10 EGB06203.1 - 0.88 9.5 3.2 0.54 10.2 0.5 2.0 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Cas1_AcylT PF07779.12 EGB06204.1 - 3e-50 171.5 0.5 4.8e-50 170.9 0.5 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p TPH PF13868.6 EGB06204.1 - 2.4e-35 121.7 122.4 2.8e-35 121.5 122.4 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain tRNA-synt_2b PF00587.25 EGB06205.1 - 3.3e-35 121.7 0.0 5.5e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGB06205.1 - 3.5e-21 75.2 0.0 6.6e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 EGB06205.1 - 3.9e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 EGB06205.1 - 3.7e-05 23.7 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CN_hydrolase PF00795.22 EGB06207.1 - 1.6e-58 198.1 0.0 1.9e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SBF_like PF13593.6 EGB06208.1 - 5.8e-63 213.1 11.4 1.1e-62 212.2 11.4 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Actin PF00022.19 EGB06208.1 - 2.5e-14 52.7 0.0 1.5e-13 50.1 0.0 2.0 1 1 0 1 1 1 1 Actin SBF PF01758.16 EGB06208.1 - 2e-06 27.6 1.8 4.5e-06 26.5 1.8 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family PKD PF00801.20 EGB06208.1 - 3.1e-05 23.7 0.3 0.00023 21.0 0.1 2.7 2 0 0 2 2 2 1 PKD domain zf_Rg PF17915.1 EGB06208.1 - 0.032 13.6 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 Reverse gyrase zinc finger ABC_tran PF00005.27 EGB06211.1 - 1e-23 84.4 0.0 1.3e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB06211.1 - 5.4e-05 23.2 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EGB06211.1 - 0.00036 20.4 0.0 0.19 11.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGB06211.1 - 0.0015 19.1 0.0 0.0023 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB06211.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGB06211.1 - 0.0025 17.3 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB06211.1 - 0.0056 16.4 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB06211.1 - 0.021 15.2 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_C7 PF01830.18 EGB06211.1 - 0.032 13.7 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase C7 family cobW PF02492.19 EGB06211.1 - 0.039 13.5 0.4 0.072 12.7 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGB06211.1 - 0.068 13.5 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGB06211.1 - 0.084 13.0 0.4 0.16 12.0 0.4 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RuvB_N PF05496.12 EGB06211.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EGB06211.1 - 0.12 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 EGB06211.1 - 0.16 12.0 0.1 0.56 10.2 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EGB06211.1 - 0.18 12.3 0.2 0.32 11.4 0.2 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGB06211.1 - 0.18 11.4 0.2 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB06212.1 - 2.8e-48 163.9 0.0 7e-23 81.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EGB06212.1 - 6.1e-44 150.0 41.8 3.1e-26 92.1 12.1 2.6 2 0 0 2 2 2 2 ABC-2 type transporter RsgA_GTPase PF03193.16 EGB06212.1 - 8.2e-11 42.1 0.5 0.00045 20.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EGB06212.1 - 1.5e-10 41.4 0.1 0.034 13.9 0.0 4.1 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB06212.1 - 1.6e-09 37.4 0.3 0.00022 20.9 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB06212.1 - 7.5e-08 33.1 0.2 0.017 15.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGB06212.1 - 3.4e-07 29.9 0.0 0.22 10.9 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EGB06212.1 - 1.1e-05 25.3 0.6 0.0059 16.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGB06212.1 - 1.1e-05 25.9 0.2 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGB06212.1 - 4.6e-05 23.7 0.5 0.3 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGB06212.1 - 5.5e-05 23.0 0.6 0.078 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGB06212.1 - 0.0002 21.4 0.9 0.59 10.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 EGB06212.1 - 0.00078 19.1 1.6 0.52 9.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 EGB06212.1 - 0.00081 18.6 8.7 0.00081 18.6 8.7 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein Rad17 PF03215.15 EGB06212.1 - 0.00094 19.1 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain PduV-EutP PF10662.9 EGB06212.1 - 0.0012 18.6 1.1 0.75 9.5 0.1 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EGB06212.1 - 0.0015 19.1 0.2 1.7 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EGB06212.1 - 0.0024 17.5 4.1 0.56 9.8 0.4 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGB06212.1 - 0.0024 18.0 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EGB06212.1 - 0.0039 17.2 0.6 4.2 7.4 0.1 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EGB06212.1 - 0.0039 17.6 0.6 2.8 8.4 0.3 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGB06212.1 - 0.0094 15.7 0.2 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGB06212.1 - 0.011 16.1 0.1 4 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 EGB06212.1 - 0.022 14.7 2.2 0.95 9.4 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 EGB06212.1 - 0.028 14.7 2.7 3.4 7.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGB06212.1 - 0.034 14.1 0.4 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGB06212.1 - 0.049 13.1 0.6 5.7 6.4 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 EGB06212.1 - 0.057 12.8 0.2 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.17 EGB06212.1 - 0.059 13.1 0.1 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein FeoB_N PF02421.18 EGB06212.1 - 0.1 12.1 1.1 7.5 6.1 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 EGB06212.1 - 0.13 12.4 0.4 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 EGB06212.1 - 0.14 11.9 0.1 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Septin PF00735.18 EGB06212.1 - 0.15 11.3 0.3 4.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Septin Mg_chelatase PF01078.21 EGB06212.1 - 0.16 11.4 0.1 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EGB06212.1 - 0.17 11.2 0.3 7.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 EGB06212.1 - 0.17 11.5 0.0 18 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 EGB06212.1 - 0.19 11.6 0.0 20 5.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGB06212.1 - 0.29 11.0 3.4 10 6.0 0.9 2.4 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 EGB06212.1 - 1.9 8.9 3.7 8.1 6.9 0.2 2.7 2 1 1 3 3 3 0 AAA domain UbiA PF01040.18 EGB06213.1 - 3.5e-44 151.0 18.7 4.7e-44 150.6 18.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family LIM PF00412.22 EGB06214.1 - 1.5e-24 85.9 4.1 4.9e-08 33.1 0.0 4.3 4 1 0 4 4 4 4 LIM domain DUF1272 PF06906.11 EGB06214.1 - 0.011 15.8 9.8 0.029 14.5 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DNA_ligase_ZBD PF03119.16 EGB06214.1 - 0.011 15.7 6.0 2 8.5 0.9 3.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-A20 PF01754.16 EGB06214.1 - 0.02 14.8 5.5 0.76 9.8 0.1 3.9 3 0 0 3 3 3 0 A20-like zinc finger RecO_C PF02565.15 EGB06214.1 - 0.3 10.9 3.2 9.5 6.0 0.8 2.5 2 1 0 2 2 2 0 Recombination protein O C terminal DUF2321 PF10083.9 EGB06214.1 - 1.8 8.2 7.3 10 5.7 1.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Fer4_10 PF13237.6 EGB06214.1 - 3.3 7.9 10.8 3.3 7.9 4.6 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain IDH PF03971.14 EGB06215.1 - 0 1148.0 0.0 0 1147.8 0.0 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase Hint PF01079.20 EGB06216.1 - 2.4e-25 89.3 0.0 4.9e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Hint module Cupin_8 PF13621.6 EGB06217.1 - 1.8e-17 63.9 0.1 8.5e-16 58.4 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain Ank_2 PF12796.7 EGB06217.1 - 1.4e-05 25.6 0.1 4.4e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB06217.1 - 0.0001 22.8 1.9 0.0045 17.5 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB06217.1 - 0.00057 20.1 0.5 0.012 15.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB06217.1 - 0.012 16.1 0.3 10 7.1 0.1 3.1 2 0 0 2 2 2 0 Ankyrin repeat Cupin_2 PF07883.11 EGB06217.1 - 0.058 13.1 0.0 1.2 8.9 0.1 2.8 3 0 0 3 3 3 0 Cupin domain Se-cys_synth_N PF12390.8 EGB06217.1 - 4.1 7.7 11.6 0.74 10.1 2.6 3.9 3 0 0 3 3 3 0 Selenocysteine synthase N terminal dCMP_cyt_deam_1 PF00383.23 EGB06218.1 - 2.2e-16 59.6 0.6 2.5e-16 59.4 0.6 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGB06218.1 - 1.1e-07 31.7 0.3 1.2e-07 31.5 0.3 1.0 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 EGB06218.1 - 0.01 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 APOBEC3 PF18771.1 EGB06218.1 - 0.026 14.6 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 NAD1 PF18778.1 EGB06218.1 - 0.075 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Glyco_hydro_28 PF00295.17 EGB06219.1 - 1.3e-32 113.2 0.5 1.8e-32 112.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EGB06219.1 - 5.7e-08 32.9 4.1 8e-06 25.8 2.3 3.4 1 1 1 2 2 2 2 Pectate lyase superfamily protein FH2 PF02181.23 EGB06220.1 - 1.6e-64 218.4 0.0 2.4e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Lipase_GDSL_2 PF13472.6 EGB06221.1 - 3e-06 27.7 2.7 9.3e-06 26.1 2.7 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB06221.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase ApbA_C PF08546.11 EGB06222.1 - 1.8e-21 76.6 0.0 2.9e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGB06222.1 - 4.4e-19 68.6 0.0 6.6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 EGB06222.1 - 0.0018 18.1 0.1 0.0036 17.1 0.1 1.4 1 0 0 1 1 1 1 Rossmann-like domain 2-Hacid_dh_C PF02826.19 EGB06222.1 - 0.054 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGB06222.1 - 0.19 11.3 0.4 0.3 10.6 0.4 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TPR_1 PF00515.28 EGB06223.1 - 7.9e-11 41.3 20.3 0.004 16.9 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06223.1 - 9.1e-08 31.7 34.0 0.0049 16.9 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06223.1 - 4.6e-05 23.3 7.4 2 8.8 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB06223.1 - 7.3e-05 23.3 6.5 7.3e-05 23.3 6.5 6.0 5 1 0 5 5 5 2 Tetratricopeptide repeat CS PF04969.16 EGB06223.1 - 8.5e-05 23.5 0.0 0.00015 22.7 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_9 PF13371.6 EGB06223.1 - 0.0012 19.0 40.1 0.094 12.9 2.4 5.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB06223.1 - 0.0016 18.1 13.0 1.3 8.7 0.6 3.6 3 0 0 3 3 3 3 TPR repeat TPR_19 PF14559.6 EGB06223.1 - 0.0055 17.2 1.7 0.0055 17.2 1.7 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat HSP20 PF00011.21 EGB06223.1 - 0.039 14.1 5.3 0.14 12.3 0.1 3.3 2 1 1 3 3 3 0 Hsp20/alpha crystallin family TPR_17 PF13431.6 EGB06223.1 - 1.3 9.6 5.6 2.8 8.5 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 EGB06225.1 - 9.4e-12 45.2 4.3 2e-07 31.3 0.5 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB06225.1 - 2.1e-11 42.5 6.4 0.0024 17.3 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB06225.1 - 2.9e-09 36.1 6.1 0.063 13.2 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EGB06225.1 - 6.2e-08 31.8 10.3 0.039 13.5 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGB06225.1 - 2.2e-06 27.4 4.6 0.067 13.0 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair DUF3977 PF13122.6 EGB06225.1 - 0.011 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3977) PTN_MK_N PF05196.13 EGB06225.1 - 0.04 14.1 0.3 0.26 11.5 0.2 2.4 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain Trm112p PF03966.16 EGB06226.1 - 7.7e-12 45.6 0.0 1.6e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 Trm112p-like protein RRM_1 PF00076.22 EGB06227.1 - 8.9e-27 92.7 0.0 1.3e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB06227.1 - 0.12 12.2 0.0 0.67 9.9 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif FliJ PF02050.16 EGB06228.1 - 0.0034 17.6 1.4 0.0059 16.8 1.4 1.4 1 0 0 1 1 1 1 Flagellar FliJ protein Apolipoprotein PF01442.18 EGB06228.1 - 0.095 12.6 9.8 0.15 11.9 9.8 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tropomyosin PF00261.20 EGB06228.1 - 0.88 8.9 7.2 1.3 8.3 7.2 1.2 1 0 0 1 1 1 0 Tropomyosin SNARE PF05739.19 EGB06228.1 - 2 8.5 3.3 1.8 8.6 0.4 2.3 2 1 0 2 2 2 0 SNARE domain YscO PF07321.12 EGB06228.1 - 4.7 7.1 17.2 30 4.5 17.2 2.2 1 1 0 1 1 1 0 Type III secretion protein YscO DUF3584 PF12128.8 EGB06228.1 - 9.5 3.6 8.1 13 3.2 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spermine_synth PF01564.17 EGB06230.1 - 2.5e-25 89.0 0.0 3.2e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGB06230.1 - 2.8e-05 23.9 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_24 PF13578.6 EGB06230.1 - 0.011 16.8 2.6 0.3 12.1 0.0 2.6 2 1 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGB06230.1 - 0.054 14.2 0.2 0.15 12.8 0.2 1.7 1 0 0 1 1 1 0 Methyltransferase domain Arm PF00514.23 EGB06231.1 - 8.2e-34 114.6 14.6 8.4e-09 35.2 0.2 8.0 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB06231.1 - 1.5e-15 57.3 4.3 5.5e-05 23.5 0.2 5.0 2 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.6 EGB06231.1 - 1.8e-12 47.5 8.2 0.086 13.4 0.1 6.5 4 2 2 6 6 6 3 HEAT-like repeat HEAT PF02985.22 EGB06231.1 - 8.4e-11 41.2 11.2 0.045 14.0 0.1 6.9 7 1 0 7 7 7 3 HEAT repeat Proteasom_PSMB PF10508.9 EGB06231.1 - 0.00035 19.2 0.0 0.0065 15.0 0.0 2.4 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit CRM1_repeat_3 PF18787.1 EGB06231.1 - 0.031 14.4 0.0 0.24 11.6 0.0 2.3 1 1 1 2 2 2 0 CRM1 / Exportin repeat 3 Ecm29 PF13001.7 EGB06231.1 - 0.05 12.3 0.0 0.85 8.2 0.0 2.5 3 0 0 3 3 3 0 Proteasome stabiliser MarR_2 PF12802.7 EGB06231.1 - 0.1 12.5 0.3 77 3.3 0.0 3.8 4 0 0 4 4 4 0 MarR family NeuB PF03102.14 EGB06233.1 - 1.7 8.1 4.9 0.25 10.7 1.0 1.6 2 0 0 2 2 2 0 NeuB family TrkH PF02386.16 EGB06234.1 - 4.4e-30 104.6 11.7 1.2e-18 66.8 1.3 3.1 3 0 0 3 3 3 3 Cation transport protein RSN1_TM PF13967.6 EGB06234.1 - 0.68 9.7 4.1 0.39 10.5 0.2 2.5 3 0 0 3 3 3 0 Late exocytosis, associated with Golgi transport Alpha-2-MRAP_C PF06401.11 EGB06235.1 - 0.029 14.4 0.1 0.046 13.7 0.1 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain YflT PF11181.8 EGB06235.1 - 0.14 12.7 0.2 0.41 11.2 0.2 1.8 1 0 0 1 1 1 0 Heat induced stress protein YflT DUF1682 PF07946.14 EGB06235.1 - 0.16 11.1 1.4 0.24 10.6 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SRCR PF00530.18 EGB06236.1 - 1e-47 160.7 23.4 1.8e-16 60.5 0.1 5.0 5 0 0 5 5 5 4 Scavenger receptor cysteine-rich domain REJ PF02010.15 EGB06236.1 - 2e-07 30.2 0.0 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 REJ domain SRCR_2 PF15494.6 EGB06236.1 - 1.9e-06 28.3 17.2 0.48 11.0 0.0 4.5 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Corona_nucleoca PF00937.18 EGB06236.1 - 1.5 7.8 3.9 2.5 7.0 3.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein His_Phos_1 PF00300.22 EGB06237.1 - 5.8e-08 32.7 0.3 2.6e-05 24.0 0.4 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) COPI_assoc PF08507.10 EGB06237.1 - 3e-05 24.1 0.7 5.7e-05 23.2 0.7 1.4 1 0 0 1 1 1 1 COPI associated protein COesterase PF00135.28 EGB06238.1 - 4.1e-44 151.3 1.9 4.5e-44 151.2 1.9 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGB06238.1 - 9.3e-13 48.5 1.9 2.7e-12 47.0 1.9 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB06238.1 - 0.00096 18.7 0.3 0.0011 18.5 0.2 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGB06238.1 - 0.0059 17.2 4.9 0.0069 17.0 4.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EGB06238.1 - 0.025 14.2 0.2 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 Putative esterase I-EGF_1 PF18372.1 EGB06240.1 - 2.4e-06 27.5 1.0 6e-06 26.2 1.0 1.7 1 0 0 1 1 1 1 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 EGB06240.1 - 0.017 15.5 2.2 0.017 15.5 2.2 2.2 2 0 0 2 2 2 0 EGF-like domain BNR PF02012.20 EGB06240.1 - 0.067 13.2 0.8 0.31 11.2 0.8 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat Glyco_hydro_43 PF04616.14 EGB06240.1 - 0.075 12.3 0.1 1.9 7.7 0.1 2.5 3 0 0 3 3 3 0 Glycosyl hydrolases family 43 DSL PF01414.19 EGB06240.1 - 0.36 11.1 2.4 0.86 9.9 2.4 1.6 1 0 0 1 1 1 0 Delta serrate ligand Laminin_EGF PF00053.24 EGB06240.1 - 0.4 10.9 4.4 0.17 12.1 1.3 1.9 2 0 0 2 2 2 0 Laminin EGF domain Mito_carr PF00153.27 EGB06241.1 - 2.8e-17 62.4 1.4 7e-05 22.7 0.0 4.6 4 1 0 4 4 4 3 Mitochondrial carrier protein DUF2285 PF10074.9 EGB06241.1 - 0.11 13.2 5.6 0.043 14.5 1.7 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) WD40 PF00400.32 EGB06242.1 - 1.4e-29 101.6 22.1 3.5e-05 24.5 0.1 11.5 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06242.1 - 3.8e-13 49.5 0.4 0.021 15.1 0.0 7.1 3 3 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGB06242.1 - 8.9e-05 22.0 0.0 0.067 12.5 0.0 4.1 4 1 1 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 EGB06242.1 - 0.0011 18.0 0.1 4.3 6.2 0.0 3.9 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 EGB06242.1 - 0.0015 19.0 3.8 0.12 13.0 0.3 5.4 7 0 0 7 7 7 1 PQQ-like domain Nup160 PF11715.8 EGB06242.1 - 0.01 14.6 1.1 2 7.0 0.1 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 TIM PF00121.18 EGB06243.1 - 2.6e-73 246.4 0.0 3.2e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Yae1_N PF09811.9 EGB06244.1 - 1.8 8.3 36.7 0.36 10.6 0.5 7.9 6 3 2 8 8 8 0 Essential protein Yae1, N terminal PDZ PF00595.24 EGB06245.1 - 0.00057 20.2 0.2 0.00097 19.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EGB06245.1 - 0.021 14.7 0.0 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 PDZ domain Ribosomal_S4 PF00163.19 EGB06246.1 - 9.3e-09 36.1 0.4 9.3e-09 36.1 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EGB06246.1 - 9.5e-09 34.8 0.1 2.1e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 S4 domain CPBP PF02517.16 EGB06247.1 - 9.8e-11 41.9 13.2 4e-10 39.9 13.1 2.2 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease DUF3246 PF11596.8 EGB06248.1 - 0.019 14.4 1.4 0.022 14.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF658 PF04936.12 EGB06248.1 - 0.11 12.2 0.8 0.14 11.9 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF658) DUF1154 PF06631.11 EGB06248.1 - 0.37 10.8 5.4 0.59 10.2 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) NOA36 PF06524.12 EGB06248.1 - 0.63 9.3 4.0 0.73 9.1 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EGB06248.1 - 2.6 6.1 6.3 2.6 6.0 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ank_4 PF13637.6 EGB06249.1 - 4e-22 78.3 5.0 4.3e-10 39.9 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB06249.1 - 3e-15 56.6 1.7 4.7e-15 55.9 1.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB06249.1 - 5.8e-15 55.2 2.9 1.2e-09 38.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB06249.1 - 4.4e-14 52.2 7.4 3.4e-05 24.1 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGB06249.1 - 1.9e-11 43.1 2.3 0.0025 18.2 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat ECH_1 PF00378.20 EGB06250.1 - 3.2e-47 160.9 0.0 3.7e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB06250.1 - 5.6e-33 114.8 0.3 9.2e-27 94.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGB06250.1 - 0.21 11.5 1.9 0.52 10.3 0.0 2.4 2 1 1 3 3 3 0 Peptidase family S49 SMC_N PF02463.19 EGB06251.1 - 6.6e-76 254.6 0.0 8.6e-76 254.2 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Dus PF01207.17 EGB06251.1 - 6.2e-51 173.3 1.1 6.2e-51 173.3 1.1 2.5 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) SMC_hinge PF06470.13 EGB06251.1 - 1.6e-22 80.0 0.1 1.6e-22 80.0 0.1 3.4 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGB06251.1 - 2.6e-12 47.2 0.0 3.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGB06251.1 - 1.5e-11 45.2 0.0 1.5e-11 45.2 0.0 4.4 4 1 1 5 5 5 1 AAA domain AAA_15 PF13175.6 EGB06251.1 - 9.1e-09 35.5 0.0 4.6e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGB06251.1 - 4.4e-06 26.3 0.0 1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGB06251.1 - 0.0031 18.0 0.0 0.49 10.9 0.0 3.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGB06252.1 - 6e-34 117.4 0.0 7.3e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGB06252.1 - 1.1e-05 25.4 0.0 1.3e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGB06252.1 - 0.035 14.3 0.0 0.068 13.4 0.0 1.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MIX PF18529.1 EGB06252.1 - 0.096 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins Ribosomal_S18 PF01084.20 EGB06252.1 - 0.17 12.1 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S18 SecA_DEAD PF07517.14 EGB06253.1 - 3e-112 374.6 0.0 5.7e-112 373.7 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 EGB06253.1 - 5.1e-38 131.1 0.0 7.9e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 EGB06253.1 - 9.7e-29 100.3 0.0 2.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 EGB06253.1 - 2.7e-06 27.2 0.0 5.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.32 EGB06254.1 - 1.3e-32 111.3 12.0 1.1e-06 29.2 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06254.1 - 2.8e-08 34.0 0.2 0.19 12.0 0.0 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB06254.1 - 0.00022 20.3 0.7 6.9 5.5 0.0 4.3 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PKD PF00801.20 EGB06254.1 - 0.12 12.3 1.1 2.1 8.2 0.3 2.9 2 1 0 2 2 2 0 PKD domain Pertussis_S2S3 PF02918.15 EGB06254.1 - 0.15 12.0 2.1 0.73 9.8 0.1 2.5 3 0 0 3 3 3 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Phage_GP20 PF06810.11 EGB06255.1 - 0.022 14.5 0.5 0.022 14.5 0.5 5.5 3 2 1 5 5 5 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 EGB06255.1 - 0.17 12.3 0.6 8.4 6.9 0.1 3.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 EGB06255.1 - 2.7 8.2 5.6 2.2 8.5 0.7 3.1 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Nucleoporin_N PF08801.11 EGB06256.1 - 8.8e-32 110.4 0.0 3.4e-17 62.3 0.0 2.0 2 0 0 2 2 2 2 Nup133 N terminal like Abhydrolase_1 PF00561.20 EGB06258.1 - 3.3e-11 43.3 0.0 4.9e-10 39.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB06258.1 - 0.001 18.4 0.1 0.0087 15.3 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGB06258.1 - 0.15 11.5 0.0 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGB06259.1 - 1.2e-24 86.9 0.0 2.9e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 zf-C3HC4_3 PF13920.6 EGB06259.1 - 1.4e-13 50.5 13.4 1.4e-13 50.5 13.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3431 PF11913.8 EGB06259.1 - 1.2e-06 28.4 0.0 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) Prok-RING_4 PF14447.6 EGB06259.1 - 4.6e-05 23.2 13.0 0.00013 21.8 13.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGB06259.1 - 0.00025 21.3 13.5 0.00025 21.3 13.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB06259.1 - 0.0039 17.0 14.0 0.011 15.6 14.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB06259.1 - 0.012 15.6 13.1 0.037 14.0 13.1 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Abhydrolase_5 PF12695.7 EGB06259.1 - 0.033 13.9 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-P11 PF03854.14 EGB06259.1 - 2.3 8.0 7.4 6.6 6.5 7.4 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 EGB06259.1 - 8 6.7 10.0 22 5.3 10.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING EF-hand_7 PF13499.6 EGB06260.1 - 1.5e-28 99.0 8.6 7e-14 52.0 0.7 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB06260.1 - 2.1e-28 95.7 11.4 2.5e-07 29.8 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB06260.1 - 9.5e-26 87.5 9.6 1.3e-06 27.8 0.5 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB06260.1 - 7e-25 85.4 8.8 1e-05 24.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB06260.1 - 8.2e-22 76.8 9.1 2.1e-10 40.3 0.6 3.3 2 2 2 4 4 4 3 EF-hand domain pair TerB PF05099.13 EGB06260.1 - 0.0038 17.2 0.1 0.99 9.4 0.1 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_11 PF08976.11 EGB06260.1 - 0.011 16.6 0.1 0.2 12.6 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB06260.1 - 0.017 15.4 0.0 2.5 8.5 0.0 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PMBR PF09373.10 EGB06260.1 - 0.03 14.5 0.0 22 5.5 0.0 3.7 4 0 0 4 4 4 0 Pseudomurein-binding repeat HicA_toxin PF07927.12 EGB06260.1 - 0.067 13.2 1.5 3.4 7.8 0.0 2.7 3 0 0 3 3 3 0 HicA toxin of bacterial toxin-antitoxin, EF-hand_4 PF12763.7 EGB06260.1 - 0.09 12.7 0.7 3 7.8 0.1 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGB06260.1 - 0.095 12.9 7.0 7.1 6.9 3.0 3.7 2 1 2 4 4 4 0 Dockerin type I domain GhoS PF11080.8 EGB06260.1 - 0.13 12.2 0.0 2.1 8.4 0.0 2.1 1 1 1 2 2 2 0 Endoribonuclease GhoS Phage_TAC_6 PF09550.10 EGB06260.1 - 2 8.9 5.5 1.4 9.4 0.7 2.8 3 1 0 3 3 3 0 Phage tail assembly chaperone protein, TAC DUF3618 PF12277.8 EGB06260.1 - 2.7 8.3 7.7 1.9 8.8 0.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3618) Pro_isomerase PF00160.21 EGB06261.1 - 5.1e-26 91.8 0.0 6.8e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_C97 PF05903.14 EGB06262.1 - 6.5e-20 71.5 0.0 7.3e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain EF-hand_1 PF00036.32 EGB06263.1 - 3.2e-07 29.4 5.4 1.1e-05 24.6 0.9 2.9 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB06263.1 - 3.9e-07 29.5 2.6 0.0019 18.0 0.4 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB06263.1 - 4.4e-07 30.3 1.3 5.4e-07 30.0 1.3 1.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB06263.1 - 2.6e-05 24.0 0.6 2.6e-05 24.0 0.6 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB06263.1 - 0.00057 19.3 0.7 0.00057 19.3 0.7 2.4 3 0 0 3 3 3 1 EF hand AAA PF00004.29 EGB06264.1 - 2.5e-17 63.5 0.0 3.5e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGB06264.1 - 0.00014 21.1 0.0 0.00018 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGB06264.1 - 0.0017 18.4 0.0 0.0076 16.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB06264.1 - 0.0037 17.7 0.1 0.01 16.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EGB06264.1 - 0.0037 17.8 0.0 0.0049 17.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 EGB06264.1 - 0.0083 16.1 0.2 1.4 8.8 0.0 2.2 1 1 1 2 2 2 2 NACHT domain Ploopntkinase3 PF18751.1 EGB06264.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 EGB06264.1 - 0.071 13.3 0.1 0.16 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGB06264.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EGB06264.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGB06264.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB06264.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGB06264.1 - 0.13 12.8 0.0 0.24 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain ITI_HC_C PF06668.12 EGB06264.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus AAA_29 PF13555.6 EGB06264.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EGB06264.1 - 0.18 11.6 0.1 0.46 10.2 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EGB06264.1 - 0.21 10.9 0.1 0.78 9.0 0.0 1.7 2 0 0 2 2 2 0 KaiC FKBP_C PF00254.28 EGB06266.1 - 1.6e-12 47.5 0.0 3.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SH3_9 PF14604.6 EGB06266.1 - 6.6e-07 29.1 0.1 1.4e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGB06266.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB06266.1 - 0.003 17.1 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 SH3 domain 2OG-FeII_Oxy_3 PF13640.6 EGB06267.1 - 0.0035 18.2 0.0 0.0067 17.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DoxX_2 PF13564.6 EGB06268.1 - 0.047 13.8 12.0 0.087 12.9 10.7 2.1 1 1 0 1 1 1 0 DoxX-like family NrfD PF03916.14 EGB06268.1 - 3.1 7.3 7.0 1.5 8.4 0.2 2.4 2 1 1 3 3 3 0 Polysulphide reductase, NrfD TPT PF03151.16 EGB06269.1 - 5.4e-14 52.2 16.6 6.8e-14 51.9 16.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UBA_4 PF14555.6 EGB06270.1 - 1.6e-09 37.4 6.1 0.0051 16.6 0.6 3.2 3 0 0 3 3 3 3 UBA-like domain HOIP-UBA PF16678.5 EGB06270.1 - 0.0002 21.4 6.0 0.064 13.3 0.4 2.7 2 1 0 2 2 2 2 HOIP UBA domain pair TAP_C PF03943.13 EGB06270.1 - 0.0016 18.0 0.1 0.74 9.5 0.0 2.9 3 0 0 3 3 3 2 TAP C-terminal domain HTH_8 PF02954.19 EGB06270.1 - 0.13 12.1 4.7 5.8 6.8 0.0 3.5 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family UBA PF00627.31 EGB06270.1 - 0.4 10.6 9.5 2.4 8.2 0.3 3.9 4 0 0 4 4 4 0 UBA/TS-N domain cNMP_binding PF00027.29 EGB06271.1 - 4e-17 62.1 0.3 8.2e-17 61.1 0.1 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGB06271.1 - 5e-11 42.4 5.2 8.1e-11 41.7 5.2 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB06271.1 - 2.9e-08 33.3 4.4 4.1e-08 32.7 4.4 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5413 PF17434.2 EGB06271.1 - 0.048 14.0 1.0 0.081 13.3 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5413) Esterase PF00756.20 EGB06272.1 - 2.1e-45 155.3 0.0 3.1e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase ADH_zinc_N PF00107.26 EGB06272.1 - 9.3e-24 83.9 0.3 2.2e-23 82.6 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB06272.1 - 1.6e-19 69.7 1.7 4.3e-19 68.4 1.7 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Hydrolase_4 PF12146.8 EGB06272.1 - 0.0015 17.9 0.1 0.0036 16.6 0.1 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AlaDh_PNT_C PF01262.21 EGB06272.1 - 0.002 17.5 4.3 0.0025 17.1 2.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EGB06272.1 - 0.002 17.5 0.1 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGB06272.1 - 0.0078 16.5 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EGB06272.1 - 0.057 13.0 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UreD PF01774.17 EGB06273.1 - 1.8e-43 148.9 1.2 2.8e-43 148.3 1.2 1.3 1 0 0 1 1 1 1 UreD urease accessory protein UreF PF01730.16 EGB06273.1 - 1.8e-21 77.1 9.8 5.4e-21 75.5 9.8 1.9 1 0 0 1 1 1 1 UreF Mito_fiss_reg PF05308.11 EGB06273.1 - 0.49 10.4 1.8 0.8 9.7 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EGB06273.1 - 1.4 8.3 6.7 2.2 7.7 6.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EGB06273.1 - 3.1 7.9 6.9 6.2 6.9 6.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Hist_deacetyl PF00850.19 EGB06274.1 - 6.4e-32 111.3 0.3 8e-32 110.9 0.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TRAPP PF04051.16 EGB06275.1 - 5.5e-35 120.2 0.1 6.6e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FYVE PF01363.21 EGB06276.1 - 6.8e-14 51.8 2.9 1e-13 51.2 2.9 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGB06276.1 - 0.075 13.2 3.6 0.14 12.4 3.6 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger HypA PF01155.19 EGB06276.1 - 0.13 12.3 0.4 0.23 11.5 0.4 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Acyl-CoA_dh_1 PF00441.24 EGB06277.1 - 9.6e-47 159.0 5.6 1.7e-46 158.1 5.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGB06277.1 - 5.3e-29 101.2 0.6 1.3e-28 99.9 0.6 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGB06277.1 - 5.6e-28 97.0 0.2 1.2e-27 95.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGB06277.1 - 2.3e-22 79.7 6.0 4.5e-22 78.8 6.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cnn_1N PF07989.11 EGB06278.1 - 0.0018 18.4 1.3 0.13 12.4 0.0 3.2 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 HR1 PF02185.16 EGB06278.1 - 0.037 14.1 3.0 0.21 11.7 1.9 2.7 2 0 0 2 2 2 0 Hr1 repeat GAS PF13851.6 EGB06278.1 - 6.4 6.1 7.4 1.1 8.6 0.1 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPT PF03151.16 EGB06279.1 - 2.5e-93 312.6 10.8 2.9e-93 312.4 10.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB06279.1 - 6.6e-10 39.3 23.1 8.5e-05 22.7 9.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGB06279.1 - 1.5e-05 24.4 9.2 2e-05 24.0 9.2 1.2 1 0 0 1 1 1 1 UAA transporter family Ephrin_rec_like PF07699.13 EGB06280.1 - 2e-17 62.7 37.0 1.3e-06 28.1 2.7 5.7 1 1 3 5 5 5 5 Putative ephrin-receptor like NCD3G PF07562.14 EGB06280.1 - 1.1e-08 34.9 24.2 0.06 13.3 3.6 4.9 2 1 4 6 6 6 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EGB06280.1 - 0.0044 17.4 27.0 1.7 9.1 0.7 6.4 2 1 1 4 4 4 3 TNFR/NGFR cysteine-rich region Response_reg PF00072.24 EGB06281.1 - 6.4e-19 68.2 0.0 7.6e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Abhydrolase_3 PF07859.13 EGB06282.1 - 7.7e-07 29.2 2.6 2.3e-06 27.6 2.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB06282.1 - 0.007 15.9 0.1 0.68 9.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EGB06282.1 - 0.012 14.5 0.1 0.058 12.3 0.1 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EGB06282.1 - 0.06 13.9 25.5 0.018 15.7 19.2 2.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB06282.1 - 0.084 12.1 0.5 0.75 9.0 0.1 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 RSN1_7TM PF02714.15 EGB06283.1 - 2.4e-40 138.6 11.1 3.2e-40 138.2 11.1 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Ricin_B_lectin PF00652.22 EGB06283.1 - 2.7e-16 60.0 0.2 3.2e-09 37.1 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain PHM7_cyt PF14703.6 EGB06283.1 - 2.1e-09 37.8 0.0 0.00019 21.7 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Glyco_hydro_130 PF04041.13 EGB06283.1 - 7e-07 28.5 0.0 1.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase RicinB_lectin_2 PF14200.6 EGB06283.1 - 0.03 15.0 0.3 0.37 11.5 0.1 2.2 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like ORMDL PF04061.14 EGB06285.1 - 3.2e-23 82.1 0.1 3.5e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 ORMDL family CbtA PF09490.10 EGB06286.1 - 0.00092 19.1 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) PBP_N PF17093.5 EGB06286.1 - 0.057 13.7 0.1 0.079 13.2 0.1 1.2 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF2207 PF09972.9 EGB06286.1 - 0.093 11.5 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spc7_N PF15402.6 EGB06286.1 - 0.37 9.0 4.6 0.46 8.7 4.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 MORN PF02493.20 EGB06287.1 - 1.1e-58 191.8 35.7 6.9e-08 31.9 0.9 11.1 11 0 0 11 11 11 10 MORN repeat Peptidase_S55 PF05580.12 EGB06287.1 - 0.0016 18.4 5.2 9.9 6.0 0.1 4.3 2 1 2 4 4 4 3 SpoIVB peptidase S55 DUF3048_C PF17479.2 EGB06287.1 - 0.0094 16.3 12.0 8.2 6.9 0.3 4.9 2 1 2 4 4 4 2 Protein of unknown function (DUF3048) C-terminal domain PATR PF12951.7 EGB06287.1 - 0.033 14.3 10.4 14 5.9 0.0 5.2 5 0 0 5 5 5 0 Passenger-associated-transport-repeat cNMP_binding PF00027.29 EGB06289.1 - 1.3e-14 54.0 0.5 2.4e-05 24.3 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Nucleotid_trans PF03407.16 EGB06290.1 - 1.1e-05 25.5 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DMRT-like PF15791.5 EGB06290.1 - 0.14 12.6 6.2 0.28 11.6 6.2 1.4 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 LRR_4 PF12799.7 EGB06291.1 - 5.2e-19 68.0 0.4 7e-06 26.3 0.0 5.3 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB06291.1 - 3.6e-16 58.7 7.0 7.1e-08 32.1 0.3 4.9 2 1 4 6 6 6 5 Leucine rich repeat LRR_6 PF13516.6 EGB06291.1 - 5.6e-10 38.5 1.3 3.6 7.9 0.0 6.1 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 EGB06291.1 - 1.6e-07 30.9 4.3 10 7.1 0.0 7.0 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_9 PF14580.6 EGB06291.1 - 0.00035 20.1 0.0 0.87 9.1 0.0 3.4 1 1 2 3 3 3 2 Leucine-rich repeat NTP_transf_3 PF12804.7 EGB06292.1 - 2e-13 51.0 3.8 2e-13 51.0 3.8 3.2 3 1 0 3 3 3 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EGB06292.1 - 3.4e-05 23.5 0.0 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase LicD PF04991.13 EGB06292.1 - 0.00069 19.8 0.0 0.002 18.3 0.0 1.6 2 0 0 2 2 2 1 LicD family IspD PF01128.19 EGB06292.1 - 0.043 13.5 1.6 0.067 12.9 0.1 2.0 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Laminin_G_3 PF13385.6 EGB06293.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily TFIIS_M PF07500.14 EGB06294.1 - 3.6e-21 75.7 0.0 7.8e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGB06294.1 - 8e-17 60.8 3.5 1.4e-16 60.0 3.5 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGB06294.1 - 2.6e-08 33.7 0.3 7.1e-08 32.4 0.3 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Lar_restr_allev PF14354.6 EGB06294.1 - 0.0009 19.6 3.7 0.048 14.0 1.2 2.9 3 0 0 3 3 3 1 Restriction alleviation protein Lar Baculo_LEF5_C PF11792.8 EGB06294.1 - 0.03 14.0 0.4 0.077 12.7 0.4 1.8 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Histone_HNS PF00816.21 EGB06294.1 - 5.3 7.9 6.7 11 6.9 4.0 2.9 2 1 0 2 2 2 0 H-NS histone family FMN_red PF03358.15 EGB06295.1 - 1.3e-26 93.2 0.1 1.5e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGB06295.1 - 7.9e-07 29.0 0.0 1.5e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Skp1_POZ PF03931.15 EGB06296.1 - 4.1e-09 36.5 0.0 8.1e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGB06296.1 - 0.051 13.8 0.0 0.066 13.5 0.0 1.3 1 1 0 1 1 1 0 BTB/POZ domain HAD PF12710.7 EGB06297.1 - 9.2e-05 22.9 3.0 9.2e-05 22.9 3.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB06297.1 - 0.0047 17.2 4.2 0.22 11.8 1.2 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB06297.1 - 0.0073 16.4 0.8 0.92 9.6 0.0 2.8 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.6 EGB06297.1 - 0.013 15.6 0.0 3.6 7.6 0.0 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase tRNA_edit PF04073.15 EGB06298.1 - 6.6e-13 48.8 0.1 1.1e-12 48.1 0.1 1.3 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain A2M PF00207.22 EGB06298.1 - 0.055 13.3 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Alpha-2-macroglobulin family tRNA_bind PF01588.20 EGB06299.1 - 7e-25 87.0 0.0 8.5e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain DNA_primase_lrg PF04104.14 EGB06300.1 - 3.4e-77 259.5 0.0 5.2e-77 258.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sel1 PF08238.12 EGB06301.1 - 4.6e-51 170.1 38.4 1.3e-08 35.3 0.2 10.6 10 1 0 10 10 10 9 Sel1 repeat DUF4123 PF13503.6 EGB06301.1 - 7.8e-06 26.3 0.1 3.2 8.2 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4123) TPR_10 PF13374.6 EGB06301.1 - 0.00026 20.8 20.9 0.1 12.5 0.0 7.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06301.1 - 0.00048 20.4 20.2 0.11 12.8 0.1 6.4 5 3 3 8 8 8 4 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB06301.1 - 0.0065 16.9 3.2 13 6.4 0.0 4.1 3 1 1 4 4 4 1 B12 binding domain EF-hand_3 PF09069.11 EGB06301.1 - 0.0081 16.6 0.1 1.8 9.0 0.0 3.4 4 0 0 4 4 3 1 EF-hand TPR_1 PF00515.28 EGB06301.1 - 0.011 15.5 28.8 0.05 13.4 0.0 7.7 10 0 0 10 10 10 0 Tetratricopeptide repeat 3D PF06725.11 EGB06301.1 - 0.014 15.6 0.2 20 5.4 0.0 3.5 3 0 0 3 3 3 0 3D domain DUF977 PF06163.11 EGB06301.1 - 0.024 14.6 1.6 4.4 7.3 0.1 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF977) TPR_7 PF13176.6 EGB06301.1 - 0.051 13.6 14.0 3.2 8.0 0.0 6.5 6 1 0 6 6 5 0 Tetratricopeptide repeat DUF4398 PF14346.6 EGB06301.1 - 0.052 14.2 3.4 0.052 14.2 3.4 4.9 4 2 1 5 5 5 0 Domain of unknown function (DUF4398) TPR_2 PF07719.17 EGB06301.1 - 2.6 8.4 0.0 2.6 8.4 0.0 10.4 12 1 1 13 13 13 0 Tetratricopeptide repeat ubiquitin PF00240.23 EGB06302.1 - 1.1e-22 79.6 0.3 1.2e-22 79.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB06302.1 - 1.5e-10 40.8 0.3 1.6e-10 40.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB06302.1 - 0.00012 22.4 0.0 0.00012 22.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB06302.1 - 0.00053 19.9 0.0 0.00053 19.9 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain FGGY_C PF02782.16 EGB06304.1 - 8.5e-07 28.9 3.8 1.1e-06 28.5 0.2 2.7 2 1 1 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGB06304.1 - 0.0006 19.5 0.0 0.0085 15.7 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain HSP90 PF00183.18 EGB06305.1 - 7.4e-67 226.4 0.0 1e-36 127.0 0.0 2.0 2 0 0 2 2 2 2 Hsp90 protein DEC-1_N PF04625.13 EGB06306.1 - 0.033 13.2 3.1 0.039 13.0 3.1 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RPN5_C PF18098.1 EGB06307.1 - 2.4e-15 56.3 3.2 5.5e-15 55.2 3.2 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 EGB06307.1 - 3.8e-15 56.3 0.1 1.6e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EGB06307.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Phos_pyr_kin PF08543.12 EGB06309.1 - 3.2e-72 242.9 3.0 3.8e-72 242.6 3.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGB06309.1 - 1.9e-05 24.2 3.5 0.0059 16.0 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Ribonuc_red_sm PF00268.21 EGB06310.1 - 3.1e-115 384.4 0.1 3.7e-115 384.2 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain ERG4_ERG24 PF01222.17 EGB06311.1 - 4.3e-96 322.3 0.3 4.9e-96 322.1 0.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGB06311.1 - 0.0074 15.8 0.2 0.021 14.4 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Rhomboid PF01694.22 EGB06312.1 - 1.6e-32 112.6 10.7 2.9e-32 111.8 10.7 1.4 1 0 0 1 1 1 1 Rhomboid family MtrF PF09472.10 EGB06312.1 - 0.019 14.3 0.4 0.19 11.2 0.2 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF2254 PF10011.9 EGB06312.1 - 0.33 9.7 2.6 0.21 10.3 0.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Fasciclin PF02469.22 EGB06313.1 - 1.4e-22 80.2 0.0 1.7e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Glyco_transf_25 PF01755.17 EGB06314.1 - 0.00084 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) PhyH PF05721.13 EGB06314.1 - 0.0025 18.1 0.1 0.034 14.4 0.1 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) EF-hand_6 PF13405.6 EGB06315.1 - 5.8e-12 44.5 0.2 0.00016 21.3 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB06315.1 - 5e-11 42.9 0.2 7.9e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB06315.1 - 3.8e-09 35.4 0.1 0.0035 16.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.10 EGB06315.1 - 4.3e-05 23.5 0.8 0.0025 17.9 0.0 2.5 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_8 PF13833.6 EGB06315.1 - 7.6e-05 22.5 0.3 1.6 8.6 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB06315.1 - 0.00015 21.1 0.3 0.26 10.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGB06315.1 - 0.0054 17.0 0.0 0.82 10.0 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain CLP1_P PF16575.5 EGB06316.1 - 1.4e-28 100.0 0.0 2.5e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DSPc PF00782.20 EGB06316.1 - 4.1e-22 78.4 0.0 6.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Neur_chan_LBD PF02931.23 EGB06316.1 - 4.3e-21 75.3 0.0 5.9e-20 71.6 0.0 2.1 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Sel1 PF08238.12 EGB06316.1 - 1.2e-16 60.7 15.2 5.6e-05 23.7 0.5 4.7 4 0 0 4 4 4 3 Sel1 repeat Neur_chan_memb PF02932.16 EGB06316.1 - 2.7e-07 30.9 0.0 5.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PAH PF02671.21 EGB06316.1 - 5e-05 23.4 0.0 9.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat PTPlike_phytase PF14566.6 EGB06316.1 - 0.00014 22.0 0.0 0.00036 20.7 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGB06316.1 - 0.0046 16.5 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AAA_22 PF13401.6 EGB06316.1 - 0.0063 16.8 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB06316.1 - 0.018 15.2 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB06316.1 - 0.26 11.6 3.3 0.24 11.8 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 EGB06317.1 - 3.2e-12 46.4 0.0 3.4e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGB06317.1 - 2.3e-11 44.6 0.0 2.4e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB06317.1 - 2.5e-05 23.9 0.0 6.2e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EGB06317.1 - 7e-05 22.7 0.0 7e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB06317.1 - 0.00026 20.9 0.0 0.00026 20.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 EGB06317.1 - 0.0036 16.0 0.0 0.0036 16.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGB06317.1 - 0.056 14.0 0.1 0.071 13.6 0.1 1.2 1 0 0 1 1 1 0 ABC transporter AAA_27 PF13514.6 EGB06317.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB06317.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Ploopntkinase3 PF18751.1 EGB06317.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 SMC_N PF02463.19 EGB06318.1 - 7.7e-10 38.6 0.0 8.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF1283 PF06932.11 EGB06318.1 - 0.049 13.8 0.5 0.092 13.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) Ldh_2 PF02615.14 EGB06319.1 - 6.9e-106 354.2 0.0 8.5e-106 353.9 0.0 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Cpn60_TCP1 PF00118.24 EGB06320.1 - 1.5e-90 304.2 13.3 2.6e-90 303.4 13.3 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ion_trans PF00520.31 EGB06320.1 - 1.4e-21 76.9 0.5 2.9e-21 75.8 0.5 1.4 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB06320.1 - 4e-11 42.7 0.6 4e-11 42.7 0.6 2.6 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 EGB06320.1 - 0.00085 19.4 0.0 0.0026 17.8 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 EGB06321.1 - 1.3e-25 89.2 0.2 6e-20 71.1 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ras PF00071.22 EGB06322.1 - 4.8e-39 133.5 0.0 7.9e-39 132.8 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGB06322.1 - 5.6e-26 91.1 0.0 6.1e-25 87.8 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB06322.1 - 1.3e-08 34.5 0.0 7.9e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB06322.1 - 0.0021 17.4 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB06322.1 - 0.0061 16.6 0.0 0.01 15.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 EGB06322.1 - 0.041 14.2 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EGB06322.1 - 0.053 12.9 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EGB06322.1 - 0.076 13.4 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGB06322.1 - 0.08 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_S10 PF00450.22 EGB06323.1 - 0.087 12.2 0.0 0.91 8.9 0.0 2.0 1 1 0 1 1 1 0 Serine carboxypeptidase DUF563 PF04577.14 EGB06324.1 - 1.8e-12 47.9 0.0 3.4e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Herpes_LMP1 PF05297.11 EGB06324.1 - 0.18 11.0 3.3 0.28 10.3 3.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Nop14 PF04147.12 EGB06324.1 - 1.1 7.4 6.2 1.5 7.0 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 EGB06324.1 - 1.7 8.7 7.5 2.5 8.1 7.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Acyl_transf_3 PF01757.22 EGB06325.1 - 2.2e-12 46.7 16.5 2.2e-12 46.7 16.5 1.8 2 0 0 2 2 2 1 Acyltransferase family PTCRA PF15028.6 EGB06325.1 - 0.2 11.3 3.4 0.67 9.7 3.4 1.8 1 0 0 1 1 1 0 Pre-T-cell antigen receptor CobN-Mg_chel PF02514.16 EGB06326.1 - 0 1135.4 0.0 0 1135.1 0.0 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 EGB06326.1 - 1.8e-51 174.4 0.8 3.8e-51 173.4 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) CmlA_N PF18456.1 EGB06326.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain Chloroa_b-bind PF00504.21 EGB06328.1 - 2.4e-31 109.4 0.1 3.9e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein 6PGD PF00393.19 EGB06329.1 - 7.6e-105 350.4 0.0 9.2e-105 350.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGB06329.1 - 5.5e-32 111.1 0.0 8.7e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGB06329.1 - 4.3 7.6 10.1 0.2 11.9 0.3 3.2 3 1 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Hydrolase_4 PF12146.8 EGB06330.1 - 9.8e-08 31.6 3.6 6.5e-07 28.9 0.1 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 EF-hand_1 PF00036.32 EGB06330.1 - 0.00014 21.1 0.0 0.00037 19.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGB06330.1 - 0.00022 21.6 0.2 0.028 14.9 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB06330.1 - 0.001 18.8 0.0 0.0032 17.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain Peptidase_S15 PF02129.18 EGB06330.1 - 0.0018 17.9 0.1 0.011 15.3 0.0 2.3 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) EF-hand_5 PF13202.6 EGB06330.1 - 0.0069 15.8 1.0 0.02 14.4 1.0 1.8 1 0 0 1 1 1 1 EF hand PIP5K PF01504.18 EGB06331.1 - 2.4e-50 171.3 0.0 4.3e-49 167.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase GCD14_N PF14801.6 EGB06331.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Rhamno_transf PF11316.8 EGB06332.1 - 4.3e-32 111.4 0.1 1.8e-16 60.3 0.2 2.3 2 0 0 2 2 2 2 Putative rhamnosyl transferase Glyco_trans_2_3 PF13632.6 EGB06332.1 - 0.092 12.6 0.1 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family group 2 GTP_CH_N PF12471.8 EGB06333.1 - 7.3e-75 251.0 0.0 1.1e-74 250.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal UPRTase PF14681.6 EGB06333.1 - 1.7e-59 200.7 0.1 3.5e-59 199.7 0.0 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase GTP_cyclohydro2 PF00925.20 EGB06333.1 - 6.8e-15 55.0 0.0 1.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II PRAI PF00697.22 EGB06333.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Ribonuc_red_lgC PF02867.15 EGB06334.1 - 2.9e-85 286.8 0.0 4.4e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGB06334.1 - 2.4e-23 81.9 0.5 7.2e-23 80.4 0.1 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGB06334.1 - 6.1e-18 65.2 0.1 1.3e-17 64.1 0.1 1.6 1 0 0 1 1 1 1 ATP cone domain Pkinase PF00069.25 EGB06335.1 - 2.4e-46 158.2 0.0 2.7e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06335.1 - 1.3e-27 96.7 0.0 1.5e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB06335.1 - 5.1e-09 36.4 0.1 0.00093 19.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB06335.1 - 2.8e-07 30.1 0.0 3.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB06335.1 - 0.00068 18.7 0.0 0.00094 18.2 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB06335.1 - 0.16 11.3 0.0 0.33 10.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Arm PF00514.23 EGB06336.1 - 6.2e-43 143.6 7.7 5.1e-10 39.0 0.0 5.0 5 0 0 5 5 5 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGB06336.1 - 4.2e-05 23.9 11.9 0.17 12.5 0.2 3.7 2 2 2 4 4 4 3 HEAT-like repeat DUF3954 PF13128.6 EGB06336.1 - 0.047 13.5 0.1 73 3.3 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3954) Arm_2 PF04826.13 EGB06336.1 - 0.08 12.4 0.0 0.68 9.3 0.0 2.2 1 1 1 2 2 2 0 Armadillo-like RTP1_C2 PF10304.9 EGB06336.1 - 0.26 11.0 5.2 5.4 6.8 0.2 3.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 2 BicD PF09730.9 EGB06336.1 - 4.7 5.5 5.7 30 2.9 0.0 2.9 2 1 1 3 3 3 0 Microtubule-associated protein Bicaudal-D LRR_4 PF12799.7 EGB06337.1 - 7.5e-17 61.2 0.8 0.0002 21.6 0.0 4.1 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB06337.1 - 8.5e-07 28.7 5.0 0.0067 16.2 1.1 3.6 1 1 4 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 EGB06337.1 - 0.00035 20.7 0.4 24 6.0 0.0 5.1 3 2 0 3 3 3 1 Leucine Rich Repeat LRR_9 PF14580.6 EGB06337.1 - 0.00067 19.2 0.0 0.12 11.9 0.0 2.5 1 1 1 2 2 2 1 Leucine-rich repeat OrgA_MxiK PF09482.10 EGB06337.1 - 0.12 12.3 1.8 0.75 9.6 0.3 2.5 1 1 1 2 2 2 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) LRR_6 PF13516.6 EGB06337.1 - 0.51 10.5 3.8 14 6.0 0.2 4.1 5 0 0 5 5 5 0 Leucine Rich repeat TPR_12 PF13424.6 EGB06338.1 - 1.6e-60 201.3 42.2 4.6e-15 55.7 5.3 7.4 2 2 5 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.6 EGB06338.1 - 2.9e-56 185.9 32.5 2.5e-11 43.1 0.3 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06338.1 - 9.3e-19 66.0 10.4 0.0006 19.8 0.2 7.0 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06338.1 - 3.5e-17 61.1 25.3 3.5e-05 23.5 0.1 7.9 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06338.1 - 4.8e-15 54.6 17.0 0.00013 21.6 0.6 7.5 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06338.1 - 4.8e-12 45.0 20.3 0.00011 22.0 1.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGB06338.1 - 7.1e-07 29.3 0.3 0.0025 18.3 0.2 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB06338.1 - 5.9e-05 23.2 7.4 3.8 8.1 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB06338.1 - 0.00021 20.8 2.9 0.023 14.1 0.2 2.1 1 1 0 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 EGB06338.1 - 0.00031 21.3 26.4 0.05 14.3 0.4 5.2 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06338.1 - 0.0006 20.4 28.0 0.17 12.8 1.0 6.7 4 2 1 7 7 6 2 Tetratricopeptide repeat Mob_Pre PF01076.19 EGB06338.1 - 0.00068 19.5 0.0 1.2 9.0 0.0 4.2 3 2 2 5 5 5 1 Plasmid recombination enzyme TPR_6 PF13174.6 EGB06338.1 - 0.0026 18.3 13.5 0.058 14.1 0.4 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat YlmH_RBD PF17774.1 EGB06338.1 - 0.0038 17.5 0.9 21 5.5 0.0 4.1 3 1 1 4 4 4 0 Putative RNA-binding domain in YlmH TPR_11 PF13414.6 EGB06338.1 - 0.0039 16.8 13.7 0.06 13.0 0.2 4.9 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 EGB06338.1 - 0.0046 17.4 8.2 1.1 9.8 1.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Tcf25 PF04910.14 EGB06338.1 - 0.01 14.9 0.0 8.3 5.4 0.0 3.0 2 1 1 3 3 3 0 Transcriptional repressor TCF25 DUF1955 PF09205.10 EGB06338.1 - 0.02 14.7 0.1 15 5.3 0.0 3.8 1 1 3 5 5 5 0 Domain of unknown function (DUF1955) pKID PF02173.17 EGB06338.1 - 0.023 14.2 11.1 5.3 6.6 0.1 5.6 6 0 0 6 6 6 0 pKID domain SMBP PF16785.5 EGB06338.1 - 0.071 13.3 2.8 0.75 10.0 0.3 3.2 1 1 3 4 4 4 0 Small metal-binding protein DUF2225 PF09986.9 EGB06338.1 - 0.1 12.3 0.0 3.6 7.3 0.0 2.9 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF5471 PF17565.2 EGB06338.1 - 0.11 12.7 6.7 29 5.0 0.0 4.8 5 1 1 6 6 5 0 Family of unknown function (DUF5471) DUF4807 PF16065.5 EGB06338.1 - 0.12 12.1 0.1 20 4.9 0.0 3.9 4 2 1 6 6 6 0 Domain of unknown function (DUF4807) Vta1_C PF18097.1 EGB06338.1 - 6.3 6.6 5.8 21 4.9 0.1 3.8 5 0 0 5 5 4 0 Vta1 C-terminal domain ABC1 PF03109.16 EGB06339.1 - 2.8e-22 79.1 0.0 4.4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB06339.1 - 0.00093 19.2 7.6 0.0016 18.4 4.8 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGB06339.1 - 0.0021 17.5 0.0 0.041 13.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Peptidase_M14 PF00246.24 EGB06340.1 - 1.4e-16 61.2 0.0 2.7e-16 60.2 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EGB06340.1 - 5.8e-12 45.9 0.0 1.4e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EGB06340.1 - 0.00033 19.8 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family adh_short PF00106.25 EGB06341.1 - 1.1e-29 103.4 0.1 1.6e-29 102.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB06341.1 - 9.8e-23 80.9 4.6 1.9e-21 76.7 4.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGB06341.1 - 5.7e-07 29.2 0.3 3e-06 26.9 0.3 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGB06341.1 - 4.2e-06 26.8 0.8 7.6e-06 25.9 0.8 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EGB06341.1 - 0.0049 16.0 0.1 0.0074 15.4 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGB06341.1 - 0.011 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_C1 PF00112.23 EGB06342.1 - 7.5e-58 196.2 5.4 1.1e-57 195.6 5.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB06342.1 - 9.4e-06 26.0 0.2 2.3e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB06342.1 - 0.092 11.5 0.5 0.91 8.2 0.2 2.0 2 0 0 2 2 2 0 Peptidase C1-like family ELO PF01151.18 EGB06343.1 - 1e-34 120.2 15.5 1.6e-34 119.6 15.5 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family Exo_endo_phos PF03372.23 EGB06345.1 - 1.6e-10 40.9 0.1 3.1e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DIOX_N PF14226.6 EGB06345.1 - 0.18 12.6 0.0 0.37 11.5 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Nudix_N_2 PF14803.6 EGB06345.1 - 0.25 11.3 6.1 0.091 12.7 0.4 2.5 2 0 0 2 2 2 0 Nudix N-terminal Ribosomal_L18A PF01775.17 EGB06346.1 - 9.1e-50 167.8 0.6 1.1e-49 167.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Acetyltransf_3 PF13302.7 EGB06347.1 - 1.3e-20 74.5 0.1 1.5e-20 74.3 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGB06347.1 - 2.4e-07 31.0 0.0 3.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EGB06347.1 - 0.00021 21.0 0.4 0.00074 19.2 0.4 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB06347.1 - 0.00024 21.0 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGB06347.1 - 0.058 13.5 0.0 0.068 13.3 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 EGB06348.1 - 4.5e-35 120.9 0.4 5.8e-35 120.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB06348.1 - 1.4e-27 96.7 0.5 1.8e-27 96.4 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB06348.1 - 6e-09 36.1 0.3 8.7e-09 35.5 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGB06348.1 - 0.0016 18.4 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 EGB06349.1 - 2.4e-35 122.2 5.5 4.8e-35 121.3 5.5 1.5 1 0 0 1 1 1 1 Subtilase family Peptidase_S8_N PF16361.5 EGB06349.1 - 0.0004 20.9 0.2 0.001 19.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal of Subtilase family SelR PF01641.18 EGB06350.1 - 1.8e-29 102.2 0.0 2.1e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain zf-tcix PF14952.6 EGB06350.1 - 0.21 11.3 4.6 0.89 9.2 0.0 2.8 3 1 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding zf-Mss51 PF13824.6 EGB06350.1 - 0.26 11.4 0.2 5.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.13 EGB06350.1 - 2 8.1 4.6 10 5.9 0.4 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit WD40 PF00400.32 EGB06351.1 - 3.4e-09 37.2 0.2 0.00085 20.1 0.0 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ PF01011.21 EGB06351.1 - 0.14 12.2 2.1 43 4.3 0.1 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 EGB06351.1 - 0.41 11.2 3.3 15 6.2 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain tify PF06200.14 EGB06351.1 - 0.54 9.6 3.7 10 5.6 0.2 2.5 2 0 0 2 2 2 0 tify domain PDEase_I PF00233.19 EGB06352.1 - 2.1e-69 233.9 0.1 2.9e-69 233.4 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EGB06352.1 - 0.033 14.4 0.7 0.069 13.4 0.6 1.5 1 1 0 1 1 1 0 HD domain Trypsin_2 PF13365.6 EGB06353.1 - 2.5e-23 83.7 7.0 3.7e-23 83.1 4.5 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_3 PF17815.1 EGB06353.1 - 6.2e-15 55.3 0.0 9.9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGB06353.1 - 3.8e-12 46.4 0.1 1e-11 45.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 EGB06353.1 - 3e-10 40.3 0.1 5.1e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ PF00595.24 EGB06353.1 - 6.1e-07 29.7 0.1 5.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGB06353.1 - 2.2e-06 27.4 1.0 1.2e-05 25.0 0.8 2.3 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 EGB06353.1 - 0.022 13.4 0.2 0.039 12.6 0.2 1.3 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S39 PF02122.15 EGB06353.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 TPR_8 PF13181.6 EGB06354.1 - 4.8e-13 48.2 9.2 0.2 11.9 0.0 8.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06354.1 - 1.5e-11 43.4 42.4 0.0039 17.2 0.4 10.2 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06354.1 - 2e-10 40.0 22.8 0.0086 15.9 0.3 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB06354.1 - 5.5e-07 29.2 1.5 0.0035 17.0 0.0 4.1 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 EGB06354.1 - 1.2e-06 28.5 9.9 0.00064 19.9 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB06354.1 - 3.5e-06 27.4 18.3 0.00052 20.5 0.9 10.6 9 2 0 9 9 6 4 Tetratricopeptide repeat EF-hand_7 PF13499.6 EGB06354.1 - 2.3e-05 24.7 3.2 0.00011 22.5 1.8 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB06354.1 - 0.00044 19.6 2.0 0.011 15.2 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB06354.1 - 0.00046 19.9 1.6 0.011 15.5 0.2 3.4 3 0 0 3 3 3 1 EF-hand domain TPR_12 PF13424.6 EGB06354.1 - 0.00049 20.3 0.6 0.00049 20.3 0.6 9.0 8 2 1 9 9 7 3 Tetratricopeptide repeat LRR_6 PF13516.6 EGB06354.1 - 0.00071 19.4 6.1 9.4 6.6 0.1 7.2 8 0 0 8 8 8 0 Leucine Rich repeat TPR_14 PF13428.6 EGB06354.1 - 0.0083 16.9 0.9 0.0083 16.9 0.9 17.0 11 5 5 16 16 9 2 Tetratricopeptide repeat LRR_4 PF12799.7 EGB06354.1 - 0.0088 16.4 0.0 2.6 8.6 0.0 4.2 5 0 0 5 5 4 1 Leucine Rich repeats (2 copies) TF_Zn_Ribbon PF08271.12 EGB06354.1 - 0.014 14.9 0.5 0.027 14.0 0.5 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding TPR_7 PF13176.6 EGB06354.1 - 0.055 13.5 16.7 4.5 7.5 0.1 8.3 8 0 0 8 8 7 0 Tetratricopeptide repeat VHP PF02209.19 EGB06354.1 - 0.1 12.7 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Villin headpiece domain EF-hand_8 PF13833.6 EGB06354.1 - 0.11 12.4 1.0 3.7 7.5 0.3 2.6 2 0 0 2 2 2 0 EF-hand domain pair TPR_6 PF13174.6 EGB06354.1 - 0.15 12.8 38.1 0.51 11.1 0.1 11.0 11 0 0 11 11 8 0 Tetratricopeptide repeat IQ PF00612.27 EGB06354.1 - 0.16 11.9 15.9 7.6 6.6 2.8 5.4 4 0 0 4 4 4 0 IQ calmodulin-binding motif Tnp_22_trimer PF17489.2 EGB06354.1 - 0.18 11.8 4.9 0.54 10.3 4.9 1.8 1 0 0 1 1 1 0 L1 transposable element trimerization domain DUF1741 PF08427.10 EGB06354.1 - 0.25 11.0 5.3 0.062 13.0 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) SBF_like PF13593.6 EGB06355.1 - 7e-78 262.1 14.2 8e-78 261.9 14.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EGB06355.1 - 5e-13 49.2 2.4 5e-13 49.2 2.4 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 EGB06355.1 - 0.0015 17.0 4.5 0.014 13.8 0.0 2.1 2 0 0 2 2 2 2 Membrane transport protein Kinesin PF00225.23 EGB06356.1 - 8.3e-95 317.5 0.0 9.3e-95 317.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB06356.1 - 7e-16 58.5 0.0 9.9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding ABC_tran PF00005.27 EGB06357.1 - 7.5e-17 62.1 0.0 5.2e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 EGB06357.1 - 3e-05 24.1 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EGB06357.1 - 0.00044 19.9 1.1 0.0027 17.3 0.5 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGB06357.1 - 0.0011 18.5 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB06357.1 - 0.0025 18.2 0.7 0.0054 17.1 0.7 1.7 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 EGB06357.1 - 0.003 17.2 0.1 0.0043 16.7 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGB06357.1 - 0.0041 17.3 0.2 0.007 16.5 0.2 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EGB06357.1 - 0.0046 16.5 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_21 PF13304.6 EGB06357.1 - 0.0058 16.5 0.2 0.019 14.8 0.1 1.8 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB06357.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 EGB06357.1 - 0.0076 15.5 0.2 0.38 9.9 0.2 2.0 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 EGB06357.1 - 0.0097 16.0 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 1 Dynamin family AAA_22 PF13401.6 EGB06357.1 - 0.012 15.9 0.5 0.035 14.4 0.4 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB06357.1 - 0.019 14.9 0.2 0.029 14.3 0.2 1.2 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EGB06357.1 - 0.022 14.8 0.2 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EGB06357.1 - 0.046 14.2 0.0 0.064 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB06357.1 - 0.049 13.3 0.6 0.047 13.4 0.6 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB06357.1 - 0.054 13.4 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGB06357.1 - 0.14 12.7 0.1 0.24 12.0 0.1 1.5 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EGB06357.1 - 0.15 12.3 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB06357.1 - 0.17 12.3 0.0 1.9 8.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EGB06357.1 - 0.17 12.3 0.1 0.83 10.1 0.2 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGB06357.1 - 0.18 11.7 0.0 2.4 8.0 0.0 2.0 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 EGB06357.1 - 0.21 11.3 0.5 0.29 10.9 0.5 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EGB06357.1 - 0.32 10.9 0.1 1.1 9.1 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 EGB06357.1 - 0.34 10.1 0.1 0.6 9.3 0.0 1.4 2 0 0 2 2 2 0 Septin ABC_membrane PF00664.23 EGB06358.1 - 1.7e-32 113.1 0.0 2.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB06358.1 - 7e-23 81.7 0.0 1.2e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB06358.1 - 0.0002 21.8 0.6 0.00062 20.2 0.6 1.8 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGB06358.1 - 0.00027 20.4 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EGB06358.1 - 0.0023 18.1 0.1 0.0036 17.4 0.1 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 EGB06358.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB06358.1 - 0.065 13.0 0.2 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGB06358.1 - 0.073 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase E1-E2_ATPase PF00122.20 EGB06359.1 - 6e-42 143.2 0.1 6e-42 143.2 0.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 EGB06359.1 - 1.3e-13 51.2 0.0 1.7e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Sulfatase PF00884.23 EGB06360.1 - 2.1e-40 139.0 0.0 2.5e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB06360.1 - 0.00072 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Rhomboid PF01694.22 EGB06362.1 - 7.8e-16 58.4 2.7 1.3e-07 31.7 0.1 2.2 2 0 0 2 2 2 2 Rhomboid family ubiquitin PF00240.23 EGB06362.1 - 1.4e-13 50.3 0.0 2.4e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 EGB06362.1 - 0.00014 21.7 3.3 0.17 11.8 0.4 2.7 1 1 1 2 2 2 2 STI1 domain Rad60-SLD PF11976.8 EGB06362.1 - 0.00093 19.0 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 EGB06362.1 - 0.04 13.6 8.1 0.023 14.4 2.7 2.9 3 0 0 3 3 3 0 XPC-binding domain Pik1 PF11522.8 EGB06362.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 CSTF2_hinge PF14327.6 EGB06362.1 - 0.13 12.7 2.8 0.27 11.7 2.8 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Nop10p PF04135.12 EGB06363.1 - 1.2e-21 76.5 0.5 1.4e-21 76.2 0.5 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family LRR_8 PF13855.6 EGB06364.1 - 3e-08 33.3 0.1 6.8e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EGB06364.1 - 0.00062 20.1 0.7 0.0021 18.4 0.7 1.9 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB06364.1 - 0.017 15.1 0.6 4.1 7.7 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat VioE PF18234.1 EGB06364.1 - 0.067 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE CLZ PF16526.5 EGB06365.1 - 0.1 13.0 8.4 4.6 7.7 1.5 3.7 2 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 EGB06365.1 - 0.41 11.0 2.3 4.1 7.8 0.2 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 EGB06365.1 - 5.7 7.0 11.0 0.34 10.9 1.7 2.9 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 EGB06365.1 - 9.6 6.4 15.0 0.096 12.8 1.7 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 EGB06365.1 - 9.6 6.6 27.6 0.35 11.3 4.7 3.2 1 1 1 3 3 3 0 Fez1 FAM76 PF16046.5 EGB06366.1 - 0.013 14.9 4.0 0.013 14.9 4.0 2.6 3 0 0 3 3 3 0 FAM76 protein zinc_ribbon_4 PF13717.6 EGB06366.1 - 2 8.4 6.0 13 5.8 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-RanBP PF00641.18 EGB06366.1 - 7.1 6.0 17.1 0.54 9.6 0.6 3.1 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others MGDG_synth PF06925.11 EGB06367.1 - 1.2e-16 61.3 0.0 1.5e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 EGB06367.1 - 3.7e-13 49.8 0.0 5.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 EGB06367.1 - 1.8e-07 31.6 1.9 2.4e-05 24.8 0.3 2.5 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB06367.1 - 0.0012 18.4 0.3 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Methyltransf_21 PF05050.12 EGB06368.1 - 0.079 13.0 0.0 0.25 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase FkbM domain Pkinase PF00069.25 EGB06369.1 - 6.1e-34 117.6 0.0 9.3e-19 67.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06369.1 - 2.7e-12 46.5 0.0 1.1e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DDT PF02791.17 EGB06370.1 - 1.1e-06 28.9 0.1 2.4e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EGB06370.1 - 6.4e-06 25.6 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DraK_HK_N PF18092.1 EGB06370.1 - 5 7.6 7.1 1.1 9.7 0.8 3.2 4 0 0 4 4 4 0 DraK Histidine Kinase N-terminal domain RPE65 PF03055.15 EGB06371.1 - 9.6e-79 265.7 0.0 1.2e-78 265.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Sel1 PF08238.12 EGB06372.1 - 1.2e-66 219.6 45.6 3.5e-10 40.2 0.4 12.5 12 0 0 12 12 12 11 Sel1 repeat TPR_16 PF13432.6 EGB06372.1 - 1.3e-08 35.4 47.5 0.00056 20.5 2.7 9.0 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06372.1 - 3.6e-05 24.0 34.9 0.058 13.7 0.3 8.8 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06372.1 - 4.4e-05 23.1 13.3 0.0018 18.0 2.3 10.8 13 0 0 13 13 13 3 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB06372.1 - 0.00012 22.5 1.7 9.2 6.8 0.0 4.6 5 0 0 5 5 4 1 B12 binding domain TPR_17 PF13431.6 EGB06372.1 - 0.00018 21.6 5.5 8.7 7.0 0.1 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat DUF977 PF06163.11 EGB06372.1 - 0.00035 20.5 2.0 0.31 11.0 0.0 4.2 3 2 1 4 4 4 1 Bacterial protein of unknown function (DUF977) TPR_10 PF13374.6 EGB06372.1 - 0.00077 19.3 39.2 0.024 14.5 0.0 10.3 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06372.1 - 0.0014 18.6 6.2 0.009 16.1 3.2 13.0 16 0 0 16 16 15 3 Tetratricopeptide repeat DUF410 PF04190.13 EGB06372.1 - 0.0034 17.2 4.3 1 9.1 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF410) YicC_N PF03755.13 EGB06372.1 - 0.055 13.9 0.8 10 6.6 0.1 3.2 3 0 0 3 3 3 0 YicC-like family, N-terminal region AAA_lid_10 PF17872.1 EGB06372.1 - 0.097 12.8 0.1 36 4.5 0.0 3.3 3 0 0 3 3 3 0 AAA lid domain Metallophos_2 PF12850.7 EGB06372.1 - 0.11 12.7 0.2 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain TPR_3 PF07720.12 EGB06372.1 - 0.2 11.7 14.3 0.26 11.3 1.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06372.1 - 0.65 10.2 0.1 0.65 10.2 0.1 10.4 9 3 1 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06372.1 - 0.71 10.2 37.0 1.8 9.0 1.4 9.8 12 0 0 12 12 11 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB06372.1 - 0.86 9.9 13.8 2.7 8.3 0.5 4.3 4 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Ank PF00023.30 EGB06373.1 - 4.3e-09 36.4 0.5 5e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGB06373.1 - 5.1e-09 36.6 0.0 1.9e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB06373.1 - 1.7e-07 31.7 0.0 9.6e-07 29.2 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB06373.1 - 7.4e-06 25.9 0.1 0.018 15.5 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGB06373.1 - 1.8e-05 24.9 0.1 5.4e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) FKBP_C PF00254.28 EGB06374.1 - 4.4e-29 100.6 0.0 4.8e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SKI PF01202.22 EGB06375.1 - 9.7e-42 142.8 0.0 1.1e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EGB06375.1 - 1.8e-05 24.9 0.1 4.3e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB06375.1 - 0.00013 22.5 0.0 0.00047 20.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGB06375.1 - 0.017 14.5 0.2 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB06375.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 EGB06375.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 EGB06375.1 - 0.11 12.9 0.2 0.15 12.4 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGB06375.1 - 0.11 12.7 0.0 0.62 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB06375.1 - 0.15 12.6 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGB06375.1 - 0.16 12.4 0.0 0.2 12.1 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4366 PF14283.6 EGB06376.1 - 1.1e-06 28.8 0.0 0.07 13.2 0.0 3.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4366) Insulin_TMD PF17870.1 EGB06376.1 - 0.026 14.6 8.6 0.85 9.7 1.1 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF2909 PF11137.8 EGB06376.1 - 0.028 14.3 9.6 1.7 8.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) SP_C-Propep PF08999.10 EGB06376.1 - 0.3 10.9 8.1 2.1 8.2 0.1 2.6 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF983 PF06170.12 EGB06376.1 - 0.45 10.9 5.1 11 6.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Flavi_NS4A PF01350.17 EGB06376.1 - 7.8 6.4 9.4 3.1 7.7 1.9 2.3 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A zf-RING_5 PF14634.6 EGB06377.1 - 0.088 12.8 0.5 0.25 11.4 0.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_transf_34 PF05637.12 EGB06377.1 - 0.91 9.2 1.8 34 4.0 2.6 2.5 2 1 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family HEAT PF02985.22 EGB06378.1 - 1.8e-12 46.4 26.2 1 9.8 0.0 11.8 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.6 EGB06378.1 - 3.7e-08 33.7 48.5 0.0002 21.7 0.2 8.2 6 4 3 9 9 9 6 HEAT repeats Vac14_Fab1_bd PF12755.7 EGB06378.1 - 6.9e-05 23.4 1.7 0.048 14.3 0.1 4.5 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGB06378.1 - 0.013 15.6 7.0 1.9 8.5 0.2 5.3 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 API5 PF05918.11 EGB06378.1 - 1.2 7.8 2.4 6.6 5.4 0.0 2.8 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) NIT PF08376.10 EGB06379.1 - 5.3e-13 50.0 28.1 5.3e-13 50.0 28.1 3.2 3 1 0 3 3 3 1 Nitrate and nitrite sensing WD40 PF00400.32 EGB06380.1 - 1.2e-07 32.2 0.9 1.2 10.1 0.0 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat EF-hand_8 PF13833.6 EGB06380.1 - 0.034 14.0 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair PP_kinase_C_1 PF17941.1 EGB06380.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 OAD_gamma PF04277.13 EGB06380.1 - 9.4 6.9 8.4 1.5 9.5 2.3 3.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Sel1 PF08238.12 EGB06381.1 - 2.3e-40 136.1 27.8 4.6e-10 39.8 0.3 7.5 7 1 0 7 7 7 6 Sel1 repeat GSH-S_N PF02951.14 EGB06381.1 - 0.0049 17.0 0.0 0.046 13.8 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, N-terminal domain TPR_12 PF13424.6 EGB06381.1 - 0.0088 16.3 22.2 0.47 10.8 0.7 6.1 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06381.1 - 0.011 15.5 5.2 0.021 14.6 1.9 7.5 11 0 0 11 11 11 0 Tetratricopeptide repeat HEXIM PF15313.6 EGB06381.1 - 0.014 15.6 0.0 5.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein TPR_3 PF07720.12 EGB06381.1 - 0.1 12.6 4.1 2.5 8.2 1.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat CZB PF13682.6 EGB06381.1 - 0.1 13.0 0.1 3.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain TPR_10 PF13374.6 EGB06381.1 - 0.42 10.5 0.0 0.42 10.5 0.0 6.9 7 1 1 8 8 8 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB06381.1 - 1.4 9.5 9.2 16 6.0 0.1 3.7 3 1 1 4 4 4 0 B12 binding domain VIT PF08487.10 EGB06381.1 - 2.8 8.2 4.0 21 5.4 0.2 3.0 3 1 0 3 3 3 0 Vault protein inter-alpha-trypsin domain 5_nucleotid PF05761.14 EGB06382.1 - 2.2e-148 495.0 0.0 2.4e-148 494.8 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family zf-RING_2 PF13639.6 EGB06383.1 - 6.1e-13 48.9 8.3 8e-13 48.5 8.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGB06383.1 - 1.5e-09 37.4 2.4 1.5e-09 37.4 2.4 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EGB06383.1 - 1.7e-07 31.4 5.2 2.7e-07 30.7 5.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGB06383.1 - 3.5e-07 30.0 4.7 4.5e-07 29.6 4.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB06383.1 - 3.9e-07 29.8 5.8 5.5e-07 29.4 5.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB06383.1 - 4.9e-07 29.5 7.9 7e-07 29.0 7.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB06383.1 - 1.7e-05 24.8 6.2 2.6e-05 24.2 6.2 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGB06383.1 - 0.0014 18.7 2.3 0.0022 18.0 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGB06383.1 - 0.0018 18.1 6.0 0.0031 17.4 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGB06383.1 - 0.0029 17.2 5.8 0.0045 16.6 5.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGB06383.1 - 0.074 13.0 7.6 0.17 11.8 7.8 1.6 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 EGB06383.1 - 0.096 12.9 7.7 4.1 7.6 7.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EGB06383.1 - 1.1 9.6 7.8 1.6 9.1 7.8 1.3 1 0 0 1 1 1 0 RING-like domain zinc_ribbon_16 PF17034.5 EGB06383.1 - 2 8.7 6.1 4.2 7.6 6.1 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family MoaC PF01967.21 EGB06384.1 - 2.1e-49 167.1 0.3 2.3e-49 166.9 0.3 1.0 1 0 0 1 1 1 1 MoaC family PhyH PF05721.13 EGB06385.1 - 3.3e-09 37.3 0.0 7.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 EGB06385.1 - 0.00028 21.7 0.0 0.0007 20.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PIH1 PF08190.12 EGB06386.1 - 2.5e-10 40.1 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 EGB06386.1 - 5.8e-05 23.4 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 EGB06386.1 - 0.0085 15.6 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Methyltransf_15 PF09445.10 EGB06387.1 - 4.4e-09 36.1 0.0 7.5e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EGB06387.1 - 0.029 15.1 0.1 0.11 13.2 0.1 2.0 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB06387.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 EF-hand_1 PF00036.32 EGB06388.1 - 7.5e-07 28.3 1.5 0.0061 16.0 0.8 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB06388.1 - 0.00032 20.0 1.4 0.0039 16.6 0.7 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGB06388.1 - 0.0033 17.8 1.7 0.5 10.9 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB06388.1 - 0.0071 16.2 1.5 0.82 9.6 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB06388.1 - 0.0094 15.8 8.8 0.29 11.2 1.3 3.4 3 0 0 3 3 3 2 EF-hand domain Thioredoxin PF00085.20 EGB06389.1 - 1e-24 86.5 0.0 1.2e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB06389.1 - 6.1e-07 29.9 0.0 9.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGB06389.1 - 1.3e-06 28.0 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGB06389.1 - 0.00027 20.7 0.0 0.00032 20.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGB06389.1 - 0.00051 20.3 0.0 0.00076 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGB06389.1 - 0.00059 19.7 0.0 0.00069 19.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EGB06389.1 - 0.0052 16.9 0.0 0.0073 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EGB06389.1 - 0.0099 15.7 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein T4_deiodinase PF00837.17 EGB06389.1 - 0.03 13.6 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase DUF2847 PF11009.8 EGB06389.1 - 0.054 13.4 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Pyr_redox_2 PF07992.14 EGB06390.1 - 8.3e-40 136.9 3.4 1.1e-39 136.5 3.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB06390.1 - 3.8e-24 85.5 4.7 2.5e-20 72.9 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB06390.1 - 2.1e-15 57.0 7.9 2.4e-14 53.6 0.1 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB06390.1 - 1.4e-06 28.2 13.1 0.027 14.1 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGB06390.1 - 1.7e-05 25.2 0.3 0.00059 20.2 0.1 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EGB06390.1 - 0.00031 20.0 11.3 0.19 10.7 5.6 3.4 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 EGB06390.1 - 0.00033 20.2 3.1 0.00033 20.2 3.1 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGB06390.1 - 0.00098 18.4 6.1 0.81 8.9 4.6 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EGB06390.1 - 0.0029 16.8 10.3 0.29 10.2 2.6 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 EGB06390.1 - 0.0073 15.0 9.8 3.7 6.2 0.0 3.4 4 0 0 4 4 4 3 HI0933-like protein FAD_binding_3 PF01494.19 EGB06390.1 - 0.013 14.8 6.5 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 EGB06390.1 - 0.013 14.7 0.0 0.035 13.2 0.0 1.6 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.6 EGB06390.1 - 0.017 15.6 0.9 0.11 13.0 0.2 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_8 PF13450.6 EGB06390.1 - 2.7 8.3 11.1 1.9 8.8 4.1 3.2 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB06391.1 - 1.2e-48 166.6 10.6 1.4e-48 166.3 10.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB06391.1 - 0.00018 20.8 3.9 0.00023 20.4 3.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB06391.1 - 0.00024 20.4 1.0 0.42 9.8 0.8 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB06391.1 - 0.00047 19.5 0.6 0.00082 18.7 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EGB06391.1 - 0.0017 17.3 3.0 0.072 11.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 EGB06391.1 - 0.0025 18.4 1.5 0.0049 17.4 1.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB06391.1 - 0.003 17.8 0.7 0.0072 16.5 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGB06391.1 - 0.03 14.3 3.2 0.082 12.9 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 EGB06391.1 - 0.072 12.3 1.0 0.13 11.5 1.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 EGB06391.1 - 0.088 12.4 0.2 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA EF-hand_7 PF13499.6 EGB06392.1 - 4.2e-12 46.4 21.5 0.04 14.4 0.5 8.1 9 0 0 9 9 9 3 EF-hand domain pair EF-hand_1 PF00036.32 EGB06392.1 - 4.3e-10 38.4 0.7 0.096 12.3 0.0 5.5 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EGB06392.1 - 1.7e-05 24.4 17.9 0.37 10.8 0.0 8.9 12 0 0 12 12 12 3 EF-hand domain DUF3349 PF11829.8 EGB06392.1 - 0.002 18.9 0.0 6.2 7.7 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3349) EF-hand_8 PF13833.6 EGB06392.1 - 0.0057 16.5 1.8 3.1 7.7 0.0 4.8 4 0 0 4 4 4 1 EF-hand domain pair EAP30 PF04157.16 EGB06392.1 - 0.021 14.1 0.0 9.6 5.4 0.0 2.7 2 0 0 2 2 2 0 EAP30/Vps36 family UAA PF08449.11 EGB06393.1 - 2.3e-53 181.4 14.9 2.6e-53 181.2 14.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB06393.1 - 3.5e-07 30.5 21.1 0.00013 22.2 11.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGB06393.1 - 0.16 11.3 10.8 0.22 10.8 5.0 2.2 2 1 0 2 2 2 0 Triose-phosphate Transporter family RCDG1 PF15725.5 EGB06393.1 - 0.18 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Helicase_C PF00271.31 EGB06394.1 - 8.1e-10 39.0 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1279 PF06916.13 EGB06394.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) WW PF00397.26 EGB06395.1 - 8.2e-17 61.0 10.9 3.4e-08 33.4 1.7 2.6 2 0 0 2 2 2 2 WW domain zf-C2HC_2 PF13913.6 EGB06395.1 - 3.4e-08 33.2 3.7 3.4e-08 33.2 3.7 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-UDP PF14569.6 EGB06395.1 - 0.36 11.0 5.5 0.091 12.9 0.6 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger HypA PF01155.19 EGB06395.1 - 4.6 7.3 5.4 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Acetyltransf_10 PF13673.7 EGB06396.1 - 1.6e-13 50.7 0.0 6.5e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGB06396.1 - 9.3e-12 45.2 0.1 1.6e-11 44.4 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGB06396.1 - 1.8e-09 37.4 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGB06396.1 - 1.8e-09 37.9 0.0 3.9e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGB06396.1 - 0.00016 21.7 0.4 0.0011 19.0 0.1 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGB06396.1 - 0.00092 19.3 0.9 0.0051 16.9 0.1 2.4 2 1 0 2 2 2 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EGB06396.1 - 0.046 13.5 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 EGB06396.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 EGB06396.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Helicase_C PF00271.31 EGB06397.1 - 1.9e-16 60.4 0.0 4.3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB06397.1 - 3.6e-07 30.1 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 EGB06397.1 - 1.2e-06 28.8 0.1 2.9e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) ATPase PF06745.13 EGB06397.1 - 1.6e-05 24.4 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 EGB06397.1 - 2.3e-05 24.8 0.1 5.1e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB06397.1 - 4e-05 23.9 0.0 9.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB06397.1 - 0.0017 18.1 0.4 0.004 16.9 0.4 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGB06397.1 - 0.03 14.4 0.0 0.42 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGB06397.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EGB06397.1 - 0.059 13.7 0.3 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 EGB06397.1 - 0.089 12.6 0.2 1.2 8.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGB06397.1 - 0.089 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CoA_trans PF01144.23 EGB06397.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Viral_helicase1 PF01443.18 EGB06397.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EGB06397.1 - 0.18 12.3 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Ferrochelatase PF00762.19 EGB06398.1 - 5.1e-105 351.1 0.0 5.7e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 EGB06398.1 - 0.0013 19.0 0.0 0.46 10.8 0.0 2.6 2 1 0 2 2 2 2 CbiX Rieske PF00355.26 EGB06399.1 - 6.4e-12 45.3 0.2 8.9e-12 44.8 0.2 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 EGB06399.1 - 2.5e-07 30.6 1.9 2.5e-07 30.6 1.9 2.2 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit Guanylate_cyc_2 PF09778.9 EGB06400.1 - 1.8e-59 200.7 0.0 2e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C70 PF12385.8 EGB06400.1 - 0.00017 21.6 0.6 0.00068 19.6 0.0 2.0 2 0 0 2 2 2 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 EGB06400.1 - 0.00046 20.8 0.1 0.019 15.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 EGB06400.1 - 0.0091 15.8 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C39 family GBP PF02263.19 EGB06402.1 - 4.3e-61 206.4 0.0 5.5e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGB06402.1 - 6.3e-11 42.2 0.0 9.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EGB06402.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGB06402.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Dynamin family RHD3 PF05879.12 EGB06402.1 - 0.22 9.6 0.0 0.32 9.1 0.0 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) polyprenyl_synt PF00348.17 EGB06403.1 - 7.6e-71 238.2 0.0 1e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Cu_amine_oxid PF01179.20 EGB06404.1 - 1.2e-28 100.2 0.0 1.8e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EGB06404.1 - 0.081 12.7 0.0 0.25 11.2 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1965) Histone PF00125.24 EGB06405.1 - 4.5e-37 127.3 2.7 4.9e-37 127.2 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGB06405.1 - 0.00025 21.4 0.1 0.00035 20.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGB06405.1 - 0.0035 17.4 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 EGB06405.1 - 0.0054 16.8 0.0 0.0072 16.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EGB06405.1 - 0.015 15.5 0.2 0.023 15.0 0.2 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 EGB06405.1 - 0.074 13.2 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) MIP PF00230.20 EGB06406.1 - 1.9e-50 171.7 12.1 2.3e-50 171.4 12.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein LRR_4 PF12799.7 EGB06408.1 - 1.1e-19 70.2 0.2 0.026 15.0 0.0 8.6 6 3 5 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB06408.1 - 5e-11 42.2 9.9 0.0022 17.7 0.0 7.8 4 3 5 9 9 9 3 Leucine rich repeat LRR_6 PF13516.6 EGB06408.1 - 5.1e-06 26.1 0.0 14 6.0 0.0 6.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.6 EGB06408.1 - 5.2e-06 26.1 2.2 0.11 12.0 0.1 4.5 2 2 2 5 5 5 2 Leucine-rich repeat LRR_1 PF00560.33 EGB06408.1 - 0.00052 20.2 2.7 58 4.8 0.0 7.9 10 2 0 10 10 10 0 Leucine Rich Repeat Radical_SAM PF04055.21 EGB06409.1 - 5.6e-12 46.4 0.0 8.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 EGB06409.1 - 8.2e-11 42.3 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family SHR-BD PF06650.12 EGB06410.1 - 0.0064 15.9 0.0 0.88 8.9 0.0 2.1 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EGB06410.1 - 0.22 11.7 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 PMSR PF01625.21 EGB06411.1 - 0.0026 18.0 2.4 0.013 15.7 2.4 2.0 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3377 PF11857.8 EGB06411.1 - 0.045 13.7 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) E1-E2_ATPase PF00122.20 EGB06412.1 - 3.3e-46 157.1 0.3 3.3e-46 157.1 0.3 3.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGB06412.1 - 6.9e-45 153.0 0.5 6.9e-45 153.0 0.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EGB06412.1 - 2.9e-18 65.3 0.0 6.2e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGB06412.1 - 2.1e-15 56.6 0.0 3.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGB06412.1 - 6.8e-14 52.7 10.0 1.2e-12 48.6 10.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB06412.1 - 2.4e-05 24.8 0.2 8.2e-05 23.1 0.2 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGB06412.1 - 0.00015 21.6 0.9 0.00027 20.8 0.9 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase BT1 PF03092.16 EGB06413.1 - 2.3e-14 52.5 13.8 4.4e-08 31.8 0.2 3.2 3 0 0 3 3 3 3 BT1 family Exostosin PF03016.15 EGB06413.1 - 4.6e-14 52.3 0.0 2.4e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 Exostosin family DUF938 PF06080.12 EGB06414.1 - 1.3e-54 185.1 0.0 2.5e-54 184.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 EGB06414.1 - 0.021 15.5 0.0 2.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB06414.1 - 0.067 13.9 0.0 0.18 12.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Sulfotransfer_1 PF00685.27 EGB06415.1 - 1.2e-50 172.4 0.0 1.4e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB06415.1 - 2.8e-09 37.7 0.0 1.8e-07 31.8 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family GMC_oxred_C PF05199.13 EGB06416.1 - 2.8e-24 86.3 0.3 3.1e-24 86.2 0.3 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Glyoxalase PF00903.25 EGB06417.1 - 1.2e-07 32.0 0.0 2.5e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGB06417.1 - 0.0004 20.6 0.1 0.00068 19.9 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ACPS PF01648.20 EGB06418.1 - 7.5e-13 48.6 0.0 1.4e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Lactamase_B_2 PF12706.7 EGB06419.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGB06419.1 - 0.0013 18.7 4.3 0.01 15.9 4.3 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2214 PF09980.9 EGB06420.1 - 7.2e-53 178.3 0.1 8.1e-53 178.2 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2214) TPR_2 PF07719.17 EGB06422.1 - 7.5 6.9 10.6 8.2 6.8 1.6 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 EGB06423.1 - 8.7e-16 57.8 0.2 1.6e-15 57.0 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 EGB06423.1 - 0.001 19.0 0.8 0.21 11.8 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat RRM_1 PF00076.22 EGB06423.1 - 0.0015 18.3 0.1 4.1 7.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGB06423.1 - 0.0028 17.7 21.7 0.01 15.9 3.5 3.0 3 0 0 3 3 3 2 Zinc knuckle TPR_19 PF14559.6 EGB06423.1 - 0.0081 16.7 6.6 0.024 15.1 0.1 4.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06423.1 - 0.015 15.1 0.0 0.079 12.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB06423.1 - 0.086 12.5 0.0 0.64 9.8 0.0 2.5 2 0 0 2 2 2 0 TPR repeat zf-CCHC_4 PF14392.6 EGB06423.1 - 0.49 10.2 9.4 0.38 10.5 0.5 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGB06423.1 - 7.7 6.3 14.5 2 8.2 4.8 3.1 2 1 0 2 2 2 0 C2H2 zinc-finger Arm PF00514.23 EGB06424.1 - 8e-39 130.5 12.5 3.4e-11 42.8 0.5 4.0 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB06424.1 - 3.1e-08 33.9 11.9 0.00077 19.8 1.1 2.8 1 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 EGB06424.1 - 2e-07 31.3 13.7 0.027 15.0 3.0 4.2 3 1 1 4 4 4 4 HEAT-like repeat HEAT PF02985.22 EGB06424.1 - 0.00087 19.3 9.9 4.8 7.7 0.2 4.5 4 1 0 4 4 4 2 HEAT repeat Atx10homo_assoc PF09759.9 EGB06424.1 - 0.0025 17.8 0.0 0.25 11.4 0.0 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EGB06424.1 - 0.0081 15.6 0.0 0.11 12.0 0.0 2.5 1 1 0 1 1 1 1 Armadillo-like KAP PF05804.12 EGB06424.1 - 0.011 13.9 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) RICTOR_N PF14664.6 EGB06424.1 - 0.039 12.9 0.1 6.4 5.7 0.0 3.2 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Tetradecapep PF08187.11 EGB06424.1 - 0.044 13.8 9.4 20 5.5 0.3 4.3 4 0 0 4 4 4 0 Myoactive tetradecapeptides family Aconitase_B_N PF11791.8 EGB06424.1 - 0.049 13.7 0.7 32 4.6 0.1 3.2 2 1 0 3 3 3 0 Aconitate B N-terminal domain HEAT_PBS PF03130.16 EGB06424.1 - 0.18 12.6 23.4 1.1 10.2 0.7 5.4 6 1 0 6 6 6 0 PBS lyase HEAT-like repeat LPP PF04728.13 EGB06424.1 - 0.95 9.9 3.0 15 6.0 0.2 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF5132 PF17195.4 EGB06424.1 - 10 6.3 8.5 0.81 9.8 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) cobW PF02492.19 EGB06425.1 - 7.3e-57 191.8 0.9 9.1e-57 191.5 0.9 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB06425.1 - 1.7e-15 56.7 0.0 3.2e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 EGB06425.1 - 0.00027 20.5 0.2 0.088 12.3 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB06425.1 - 0.00063 19.7 0.1 0.57 10.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB06425.1 - 0.002 18.6 0.0 0.0075 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EGB06425.1 - 0.013 14.5 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EGB06425.1 - 0.027 14.7 0.2 0.1 12.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 EGB06425.1 - 0.032 14.0 0.1 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.14 EGB06425.1 - 0.042 13.7 0.4 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EGB06425.1 - 0.045 14.0 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 EGB06425.1 - 0.055 14.0 0.0 0.096 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGB06425.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 EGB06425.1 - 0.088 12.8 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGB06425.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB06425.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EGB06425.1 - 0.16 11.6 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EGB06425.1 - 0.19 10.8 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MMR_HSR1 PF01926.23 EGB06425.1 - 0.22 11.6 0.8 1.4 9.0 0.8 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-MYND PF01753.18 EGB06426.1 - 2.3e-09 37.2 13.8 3.7e-09 36.5 13.8 1.4 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 EGB06426.1 - 0.045 14.1 3.4 0.097 13.1 3.4 1.5 1 0 0 1 1 1 0 Rhodanase C-terminal zf-C6H2 PF15801.5 EGB06426.1 - 5.7 7.3 10.4 10 6.5 10.4 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Myotub-related PF06602.14 EGB06427.1 - 1.9e-105 352.7 0.0 2.4e-105 352.4 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 EGB06427.1 - 0.0029 17.4 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGB06427.1 - 0.0052 16.8 0.1 0.016 15.2 0.1 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGB06427.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Aldose_epim PF01263.20 EGB06428.1 - 1e-25 90.7 0.0 2.1e-25 89.6 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase Yae1_N PF09811.9 EGB06430.1 - 2.7e-05 23.8 57.6 0.00018 21.2 1.2 10.8 3 2 9 12 12 12 10 Essential protein Yae1, N terminal Gly-zipper_YMGG PF13441.6 EGB06430.1 - 0.015 15.0 7.5 0.015 15.0 7.5 7.9 3 2 5 8 8 8 0 YMGG-like Gly-zipper Ribosomal_L32p PF01783.23 EGB06431.1 - 4.2e-07 30.1 1.2 5e-07 29.9 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Mob1_phocein PF03637.17 EGB06432.1 - 2e-25 89.7 0.0 2.7e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Dpy-30 PF05186.13 EGB06433.1 - 4.6e-19 67.8 0.2 5.2e-19 67.7 0.2 1.1 1 0 0 1 1 1 1 Dpy-30 motif Myb_DNA-binding PF00249.31 EGB06434.1 - 3.3e-31 107.2 2.1 5e-17 61.8 0.2 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB06434.1 - 1.6e-23 82.7 0.2 7.9e-17 61.3 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGB06434.1 - 0.016 15.5 0.7 0.84 10.0 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 EGB06434.1 - 0.072 13.0 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 Myb DNA-binding like Sigma70_r4_2 PF08281.12 EGB06434.1 - 0.086 12.5 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 Peptidase_M16_C PF05193.21 EGB06435.1 - 2.1e-21 76.8 0.0 3.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGB06435.1 - 1.4e-12 47.8 0.0 2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Aldo_ket_red PF00248.21 EGB06436.1 - 7.4e-42 143.5 0.0 1.4e-39 136.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family zf-TAZ PF02135.16 EGB06437.1 - 0.00061 20.2 0.2 0.0017 18.8 0.2 1.7 1 0 0 1 1 1 1 TAZ zinc finger Ank_5 PF13857.6 EGB06437.1 - 0.0041 17.4 0.4 1 9.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB06437.1 - 0.0042 17.6 0.1 0.049 14.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB06437.1 - 0.0065 16.9 0.0 0.26 12.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EGB06437.1 - 0.037 14.6 0.2 0.48 11.1 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) TFIIB_C_1 PF18542.1 EGB06437.1 - 3.9 7.6 11.0 1.2 9.2 1.8 3.6 3 0 0 3 3 3 0 Transcription factor IIB C-terminal module 1 Rab5ip PF07019.12 EGB06438.1 - 3.8e-15 56.2 4.1 4.4e-15 56.0 4.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) NicO PF03824.16 EGB06439.1 - 5.5e-41 140.8 5.1 8.4e-41 140.2 5.1 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein Rad10 PF03834.14 EGB06440.1 - 3.9e-40 136.4 0.1 5.4e-40 136.0 0.1 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EGB06440.1 - 8.2e-06 26.3 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EGB06440.1 - 0.0024 17.9 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Alanine_zipper PF11839.8 EGB06440.1 - 0.64 10.4 14.0 1.4 9.4 14.0 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Tubulin PF00091.25 EGB06441.1 - 6.6e-14 52.6 0.0 7.1e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin PF00091.25 EGB06442.1 - 3.6e-23 82.8 0.0 3.9e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 EGB06442.1 - 0.031 14.0 0.0 0.032 13.9 0.0 1.0 1 0 0 1 1 1 0 Tubulin domain Com_YlbF PF06133.11 EGB06443.1 - 0.019 15.5 0.1 0.023 15.3 0.1 1.0 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA TPR_2 PF07719.17 EGB06444.1 - 1.5e-14 52.8 2.6 3.7e-05 23.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06444.1 - 2.4e-14 52.5 1.6 2e-06 27.4 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB06444.1 - 4.6e-08 33.6 10.5 6.6e-05 23.5 1.7 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06444.1 - 7.3e-08 32.6 5.8 0.0002 21.9 0.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB06444.1 - 8.6e-08 32.6 9.6 2.9e-06 27.7 5.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB06444.1 - 9.5e-08 32.1 0.3 1.7e-07 31.2 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06444.1 - 3.9e-07 29.8 0.5 0.025 14.8 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB06444.1 - 1.2e-05 25.2 3.7 0.00095 19.2 0.5 2.7 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EGB06444.1 - 1.9e-05 25.0 6.7 0.01 16.4 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB06444.1 - 3.4e-05 23.4 5.0 0.0089 15.7 0.3 3.3 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 EGB06444.1 - 0.0011 19.1 1.7 0.15 12.5 0.1 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 EGB06444.1 - 0.0013 18.8 0.3 0.18 11.9 0.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 EGB06444.1 - 0.0037 17.2 0.2 0.6 10.3 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB06444.1 - 0.004 17.4 3.9 0.0091 16.2 1.3 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGB06444.1 - 0.0044 17.3 1.5 0.077 13.3 0.2 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat VWA_2 PF13519.6 EGB06444.1 - 0.028 15.1 0.4 1.6 9.4 0.0 2.5 1 1 1 2 2 2 0 von Willebrand factor type A domain DUF4919 PF16266.5 EGB06444.1 - 0.29 11.1 2.6 1 9.3 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) DUF1995 PF09353.10 EGB06445.1 - 1.9e-13 50.9 0.1 4.3e-13 49.8 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) ETF PF01012.21 EGB06445.1 - 2.5 8.0 6.5 4.9 7.0 6.5 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein domain ABC1 PF03109.16 EGB06446.1 - 3.2e-30 104.7 0.0 5.9e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 EGB06446.1 - 0.0081 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 EGB06446.1 - 0.064 13.2 0.2 0.064 13.2 0.2 4.3 3 2 0 3 3 3 0 Phosphotransferase enzyme family HAGH_C PF16123.5 EGB06447.1 - 3.7e-18 65.8 0.0 5.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGB06447.1 - 3.6e-15 56.5 0.9 2.2e-13 50.7 0.9 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGB06447.1 - 0.00025 20.6 0.0 0.00051 19.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain IU_nuc_hydro PF01156.19 EGB06448.1 - 1.8e-12 47.4 0.9 3.4e-10 40.0 0.0 2.7 1 1 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase DUF1593 PF07632.11 EGB06448.1 - 0.11 12.0 0.1 0.35 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) Ribosomal_L2_C PF03947.18 EGB06450.1 - 2.7e-45 153.7 2.3 4.4e-45 152.9 2.0 1.5 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGB06450.1 - 3.4e-13 49.4 0.2 8.1e-13 48.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Sulfatase PF00884.23 EGB06451.1 - 9.5e-42 143.5 0.0 1.6e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EGB06451.1 - 5.9e-06 25.2 0.0 8.1e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 EGB06451.1 - 0.078 13.3 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Peptidase_M16 PF00675.20 EGB06452.1 - 1.2e-33 116.2 0.0 1.5e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGB06452.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain A_deamin PF02137.18 EGB06453.1 - 5.6e-32 111.5 0.0 9.9e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain RCC1 PF00415.18 EGB06454.1 - 1.4e-10 41.6 9.0 0.00033 21.2 0.1 5.4 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB06454.1 - 4.9e-05 23.0 23.9 0.016 15.0 0.2 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat zf-Di19 PF05605.12 EGB06454.1 - 5.1e-05 23.5 0.3 0.00012 22.3 0.3 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-GRF PF06839.12 EGB06454.1 - 0.00014 21.9 2.2 0.00038 20.5 2.2 1.8 1 0 0 1 1 1 1 GRF zinc finger NUDIX PF00293.28 EGB06454.1 - 0.00061 19.8 0.0 0.0031 17.6 0.0 2.2 2 0 0 2 2 2 1 NUDIX domain EF-hand_1 PF00036.32 EGB06454.1 - 0.0092 15.5 0.8 2.7 7.8 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB06454.1 - 0.049 13.6 0.2 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Lipase_GDSL_2 PF13472.6 EGB06457.1 - 0.00025 21.5 0.0 0.00039 20.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB06457.1 - 0.015 15.2 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Sel1 PF08238.12 EGB06459.1 - 1.5e-24 85.8 15.0 3.2e-08 34.0 0.5 4.4 4 1 0 4 4 4 4 Sel1 repeat TPR_8 PF13181.6 EGB06459.1 - 0.0027 17.8 6.9 0.26 11.6 0.4 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06459.1 - 0.0073 16.6 8.7 0.19 12.1 0.8 3.8 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB06459.1 - 0.013 15.4 7.6 1.7 8.6 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB06459.1 - 0.013 15.8 0.3 1.6 9.3 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06459.1 - 0.025 14.4 11.8 0.15 12.0 1.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EGB06459.1 - 0.11 12.6 4.1 0.25 11.4 0.4 2.8 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EGB06459.1 - 0.2 11.8 5.8 6.3 7.1 0.4 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06459.1 - 0.57 10.4 16.3 1.2 9.5 1.7 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat SAM_1 PF00536.30 EGB06460.1 - 2e-06 28.2 0.0 3.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGB06460.1 - 4e-06 26.8 0.0 7.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Peptidase_C48 PF02902.19 EGB06462.1 - 2.7e-33 115.6 0.0 3.4e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Transket_pyr PF02779.24 EGB06463.1 - 1.9e-47 161.2 0.1 3e-47 160.6 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGB06463.1 - 1.7e-40 137.7 0.2 3.6e-40 136.7 0.2 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Trypan_PARP PF05887.11 EGB06464.1 - 0.00011 22.2 44.3 0.0021 18.0 44.5 2.3 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TMEM154 PF15102.6 EGB06464.1 - 0.0027 17.6 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 EGB06464.1 - 0.0079 16.0 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4366 PF14283.6 EGB06464.1 - 0.023 14.8 4.0 0.89 9.6 4.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4519 PF15012.6 EGB06464.1 - 0.051 13.8 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF4690 PF15756.5 EGB06464.1 - 0.46 11.1 7.1 1.3 9.7 7.1 1.8 1 1 0 1 1 1 0 Small Novel Rich in Cartilage FA_desaturase PF00487.24 EGB06465.1 - 4e-35 121.9 18.3 4e-35 121.9 18.3 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGB06465.1 - 4e-13 49.3 0.1 1.1e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain His_Phos_1 PF00300.22 EGB06466.1 - 4.4e-32 111.4 0.0 5.1e-26 91.6 0.0 2.7 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) DUF2151 PF10221.9 EGB06467.1 - 0.19 10.3 0.3 0.26 9.8 0.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator AAA_11 PF13086.6 EGB06467.1 - 0.3 10.8 3.1 0.63 9.8 3.1 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_S49_N PF08496.10 EGB06467.1 - 1.6 8.8 12.6 0.13 12.4 6.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal XRN_M PF17846.1 EGB06467.1 - 4.1 6.2 7.2 7.5 5.4 7.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain HAUS6_N PF14661.6 EGB06467.1 - 6.1 6.3 8.6 13 5.3 8.6 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Complex1_LYR PF05347.15 EGB06468.1 - 8.7e-05 22.5 0.1 0.00012 22.1 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) GlyL_C PF12524.8 EGB06469.1 - 0.12 12.5 0.4 12 6.2 0.0 2.7 2 0 0 2 2 2 0 dsDNA virus glycoprotein L C terminal Pyr_redox_2 PF07992.14 EGB06470.1 - 1.7e-06 27.5 0.4 6e-06 25.7 0.2 1.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB06470.1 - 5.3e-06 26.6 0.5 0.00024 21.3 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGB06470.1 - 0.00094 19.7 0.5 0.98 10.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB06470.1 - 0.0081 15.4 1.6 0.093 12.0 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB06470.1 - 0.019 14.6 4.2 0.28 10.7 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGB06470.1 - 0.027 13.7 0.7 0.15 11.3 0.0 2.5 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 EGB06470.1 - 0.95 9.4 0.0 0.95 9.4 0.0 3.3 5 0 0 5 5 5 0 FAD-NAD(P)-binding PH PF00169.29 EGB06472.1 - 4.3e-45 152.5 0.0 1.4e-15 57.7 0.0 4.2 4 0 0 4 4 4 4 PH domain PH_8 PF15409.6 EGB06472.1 - 7e-20 71.1 0.3 4.9e-06 26.7 0.0 4.3 4 0 0 4 4 4 3 Pleckstrin homology domain PH_11 PF15413.6 EGB06472.1 - 1.8e-11 44.4 13.9 0.0023 18.3 0.9 5.8 4 2 0 4 4 4 3 Pleckstrin homology domain PH_2 PF08458.10 EGB06472.1 - 2.1e-05 24.8 0.0 0.065 13.6 0.0 3.4 3 0 0 3 3 3 1 Plant pleckstrin homology-like region PH_9 PF15410.6 EGB06472.1 - 0.00089 19.6 2.8 20 5.6 0.1 4.5 3 2 0 3 3 3 0 Pleckstrin homology domain EF-hand_6 PF13405.6 EGB06472.1 - 0.0015 18.3 0.5 0.018 15.0 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGB06472.1 - 0.0025 17.3 0.1 0.0063 16.0 0.1 1.7 1 0 0 1 1 1 1 EF hand PH_13 PF16652.5 EGB06472.1 - 0.0058 16.4 0.0 3.8 7.3 0.0 3.0 4 0 0 4 4 4 1 Pleckstrin homology domain PH_4 PF15404.6 EGB06472.1 - 0.056 13.2 0.0 25 4.6 0.0 3.7 3 0 0 3 3 3 0 Pleckstrin homology domain EF-hand_5 PF13202.6 EGB06472.1 - 0.12 11.9 0.4 0.28 10.8 0.4 1.5 1 0 0 1 1 1 0 EF hand PH_6 PF15406.6 EGB06472.1 - 0.22 11.8 12.4 1.1 9.6 0.1 4.3 4 1 1 5 5 5 0 Pleckstrin homology domain DUF966 PF06136.13 EGB06472.1 - 1 9.0 7.1 1.9 8.1 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFIIA PF03153.13 EGB06472.1 - 2.2 8.2 6.4 4 7.3 6.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 EGB06473.1 - 9.8e-25 87.7 17.5 9.8e-25 87.7 17.5 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EGB06473.1 - 3.5e-13 49.6 0.2 8.4e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 NUC130/3NT domain FMN_red PF03358.15 EGB06474.1 - 2.2e-24 86.0 0.0 2.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGB06474.1 - 0.064 13.0 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold Kinesin PF00225.23 EGB06475.1 - 1.7e-73 247.4 0.1 2.1e-73 247.1 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB06475.1 - 0.057 13.4 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Microtubule binding DUF5420 PF17457.2 EGB06475.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5420) PCMT PF01135.19 EGB06476.1 - 6.8e-21 75.0 0.0 8.3e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EGB06476.1 - 0.00071 20.6 0.0 0.0015 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB06476.1 - 0.061 13.1 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HALZ PF02183.18 EGB06477.1 - 0.029 14.6 0.9 0.029 14.6 0.9 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DASH_Spc34 PF08657.10 EGB06477.1 - 5.9 6.6 14.4 0.72 9.6 9.4 1.8 1 1 1 2 2 2 0 DASH complex subunit Spc34 TMPIT PF07851.13 EGB06477.1 - 9 5.4 7.5 15 4.7 7.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein WD40 PF00400.32 EGB06479.1 - 2.1e-17 63.1 16.4 0.0014 19.4 0.0 8.9 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06479.1 - 1e-05 25.7 0.2 6 7.3 0.0 5.6 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB06479.1 - 0.04 12.6 0.0 0.88 8.1 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Hira PF07569.11 EGB06479.1 - 0.058 13.1 0.0 8 6.1 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split PQQ PF01011.21 EGB06479.1 - 0.067 13.1 0.3 6.3 6.9 0.0 3.8 3 0 0 3 3 3 0 PQQ enzyme repeat BBS2_Mid PF14783.6 EGB06479.1 - 0.11 12.6 0.0 1.9 8.6 0.0 2.9 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EGB06479.1 - 0.17 10.6 0.0 8.1 5.1 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Sel1 PF08238.12 EGB06480.1 - 1.6e-105 343.1 83.9 5.6e-08 33.2 0.3 24.4 24 0 0 24 24 24 20 Sel1 repeat AAA_lid_10 PF17872.1 EGB06480.1 - 2.7e-06 27.4 0.1 2.2 8.5 0.0 5.6 5 0 0 5 5 5 1 AAA lid domain DUF4123 PF13503.6 EGB06480.1 - 5.9e-06 26.7 0.1 4.5 7.7 0.0 5.1 5 0 0 5 5 5 2 Domain of unknown function (DUF4123) TPR_12 PF13424.6 EGB06480.1 - 1.4e-05 25.3 50.5 0.16 12.2 0.3 12.6 11 3 2 13 13 13 4 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB06480.1 - 2.1e-05 24.9 7.0 22 5.6 0.1 7.1 7 0 0 7 7 7 0 B12 binding domain TPR_1 PF00515.28 EGB06480.1 - 7.3e-05 22.4 63.1 0.16 11.8 0.1 15.9 18 0 0 18 18 18 5 Tetratricopeptide repeat Flu_M1_C PF08289.11 EGB06480.1 - 0.00023 21.3 0.1 15 5.9 0.0 5.1 5 0 0 5 5 5 0 Influenza Matrix protein (M1) C-terminal domain TPR_17 PF13431.6 EGB06480.1 - 0.0037 17.6 5.8 53 4.5 0.0 7.8 7 0 0 7 7 6 0 Tetratricopeptide repeat PhoD PF09423.10 EGB06480.1 - 0.0051 15.9 2.6 5.5 5.9 0.1 4.8 5 0 0 5 5 5 1 PhoD-like phosphatase CathepsinC_exc PF08773.11 EGB06480.1 - 0.063 13.5 0.0 35 4.7 0.0 3.7 3 0 0 3 3 3 0 Cathepsin C exclusion domain TPR_10 PF13374.6 EGB06480.1 - 0.067 13.1 50.3 1.3 9.0 0.0 14.6 19 1 1 20 20 19 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06480.1 - 0.22 11.6 26.6 4.4 7.6 0.0 11.0 12 1 1 13 13 11 0 Tetratricopeptide repeat Rubrerythrin PF02915.17 EGB06480.1 - 0.4 11.1 3.4 2.3 8.6 0.1 3.4 3 1 0 3 3 3 0 Rubrerythrin DUF410 PF04190.13 EGB06480.1 - 0.76 9.5 10.8 7.8 6.2 0.1 5.1 5 1 0 6 6 6 0 Protein of unknown function (DUF410) TPR_8 PF13181.6 EGB06480.1 - 3 8.3 36.9 14 6.2 0.1 12.2 13 0 0 13 13 13 0 Tetratricopeptide repeat PKD_channel PF08016.12 EGB06482.1 - 3.2e-11 42.6 0.6 1.4e-09 37.2 0.6 2.1 1 1 0 1 1 1 1 Polycystin cation channel Lipase_GDSL_2 PF13472.6 EGB06483.1 - 2.1e-17 64.1 0.0 2.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB06483.1 - 1.5e-06 28.3 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LRR_6 PF13516.6 EGB06484.1 - 0.00069 19.5 0.4 3.4 7.9 0.2 3.1 3 0 0 3 3 3 3 Leucine Rich repeat fn3 PF00041.21 EGB06485.1 - 7.7e-15 55.0 0.2 2.2e-05 24.7 0.0 4.9 4 1 0 4 4 4 3 Fibronectin type III domain WD40 PF00400.32 EGB06485.1 - 1.3e-07 32.2 0.6 2e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Pur_ac_phosph_N PF16656.5 EGB06485.1 - 1.4e-06 28.7 0.0 0.0069 16.9 0.0 3.3 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 EGB06485.1 - 0.059 13.2 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Tissue factor Kinesin PF00225.23 EGB06486.1 - 1.7e-91 306.6 0.0 1.9e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB06486.1 - 5.3e-23 81.6 0.0 7.6e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding Mpv17_PMP22 PF04117.12 EGB06487.1 - 4.2e-17 62.1 4.2 7.9e-17 61.2 4.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pkinase PF00069.25 EGB06488.1 - 5.9e-62 209.4 0.0 6.6e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06488.1 - 1.5e-40 139.2 0.0 1.7e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB06488.1 - 1.4e-06 27.8 0.0 9.2e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB06488.1 - 0.00016 20.6 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB06488.1 - 0.0069 16.3 1.0 0.33 10.8 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB06488.1 - 0.058 12.7 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ion_trans PF00520.31 EGB06489.1 - 8.4e-14 51.4 3.7 1.3e-13 50.8 3.7 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB06489.1 - 6.1e-06 26.2 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MerR-DNA-bind PF09278.11 EGB06489.1 - 0.11 13.1 3.2 0.22 12.1 1.8 2.1 2 0 0 2 2 2 0 MerR, DNA binding ATG_C PF09333.11 EGB06490.1 - 0.094 13.1 3.2 1.2 9.6 0.0 3.0 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Palm_thioest PF02089.15 EGB06492.1 - 1.4e-61 208.4 0.0 1.6e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase cNMP_binding PF00027.29 EGB06493.1 - 1.6e-29 101.8 0.1 2.8e-14 52.9 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain DFP PF04127.15 EGB06494.1 - 4.8e-23 82.0 0.1 1.3e-12 47.9 0.1 2.4 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein FAD-oxidase_C PF02913.19 EGB06495.1 - 1.1e-49 169.3 0.0 1.8e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGB06495.1 - 9.3e-39 132.3 2.4 1.6e-38 131.5 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain PYC_OADA PF02436.18 EGB06496.1 - 4.7e-66 222.3 0.0 8.1e-66 221.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_D2 PF02786.17 EGB06496.1 - 6.3e-66 221.9 0.0 9.9e-66 221.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGB06496.1 - 1.7e-39 134.8 0.1 4e-39 133.6 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGB06496.1 - 2.3e-29 101.6 0.0 9.1e-29 99.7 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGB06496.1 - 3.2e-26 92.5 0.0 8.3e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGB06496.1 - 3.7e-15 55.5 7.4 8.7e-15 54.3 7.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGB06496.1 - 4.3e-07 29.7 0.0 7.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EGB06496.1 - 2.3e-06 27.3 8.6 4.8e-05 23.1 3.6 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EGB06496.1 - 0.00012 22.1 0.0 0.00038 20.5 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EGB06496.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain DUF3182 PF11379.8 EGB06496.1 - 0.004 16.2 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3182) ATPgrasp_ST PF14397.6 EGB06496.1 - 0.017 14.4 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 EGB06496.1 - 0.12 11.6 4.9 1.9 7.7 0.2 2.7 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Ion_trans_2 PF07885.16 EGB06497.1 - 1.3e-09 37.9 4.0 2.6e-09 36.9 3.9 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB06497.1 - 9.1e-06 25.1 3.1 1.1e-05 24.8 3.1 1.1 1 0 0 1 1 1 1 Ion transport protein Tmemb_40 PF10160.9 EGB06497.1 - 0.011 15.2 1.9 0.022 14.2 1.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein IRK PF01007.20 EGB06497.1 - 0.046 13.5 1.4 0.066 13.0 1.4 1.2 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain HSP70 PF00012.20 EGB06498.1 - 5.5e-19 67.8 2.9 1.2e-16 60.0 0.3 3.0 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EGB06498.1 - 0.00011 21.2 0.5 0.0013 17.6 0.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Acyl-CoA_dh_1 PF00441.24 EGB06499.1 - 3.2e-29 102.1 1.0 5.9e-29 101.2 1.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGB06499.1 - 2.3e-25 89.4 0.1 5e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGB06499.1 - 2.8e-17 62.7 0.0 4.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGB06499.1 - 2e-09 37.8 0.4 2e-09 37.8 0.4 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain T2SSE_N PF05157.15 EGB06500.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Ribosomal_L34e PF01199.18 EGB06501.1 - 3.6e-37 126.5 6.6 3.6e-37 126.5 6.6 1.4 2 0 0 2 2 2 1 Ribosomal protein L34e SET PF00856.28 EGB06502.1 - 0.00093 19.6 0.0 0.0024 18.3 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGB06503.1 - 1.7 8.8 24.5 0.056 13.5 18.1 1.9 2 0 0 2 2 2 0 MYND finger Metallophos PF00149.28 EGB06504.1 - 1.1e-24 88.1 0.0 1.3e-24 87.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SHOCT PF09851.9 EGB06505.1 - 0.00012 21.6 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 Short C-terminal domain HC2 PF07382.11 EGB06505.1 - 0.061 13.4 33.1 0.24 11.5 28.2 1.8 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 GvpG PF05120.12 EGB06505.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G ASFV_J13L PF05568.11 EGB06505.1 - 0.88 9.3 4.0 1.7 8.4 4.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Fringe PF02434.16 EGB06506.1 - 9.8e-06 25.2 0.0 0.019 14.4 0.0 2.2 2 0 0 2 2 2 2 Fringe-like DUF604 PF04646.12 EGB06506.1 - 0.009 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Galactosyl_T PF01762.21 EGB06506.1 - 0.02 14.7 0.0 0.07 12.9 0.0 1.7 2 0 0 2 2 2 0 Galactosyltransferase Sel1 PF08238.12 EGB06507.1 - 9.4e-36 121.5 22.0 1.4e-09 38.3 0.5 6.4 6 0 0 6 6 6 6 Sel1 repeat TPR_3 PF07720.12 EGB06507.1 - 0.044 13.8 1.3 0.28 11.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF410 PF04190.13 EGB06507.1 - 0.16 11.8 0.2 9.1 6.0 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_12 PF13424.6 EGB06507.1 - 3.1 8.2 13.2 5 7.5 0.6 5.2 3 3 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 EGB06508.1 - 5.5e-40 134.6 7.0 3e-06 27.8 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06508.1 - 6.8e-14 51.9 0.1 5.5e-05 23.4 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB06508.1 - 3.4e-07 29.5 1.0 0.0097 14.9 0.0 3.5 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EGB06508.1 - 3.7e-06 26.7 2.9 1.5e-05 24.7 1.2 2.3 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 EGB06508.1 - 0.00046 19.0 0.1 3.3 6.2 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGB06508.1 - 0.00085 19.7 8.1 3.4 8.3 0.1 5.6 5 1 1 6 6 6 1 PQQ-like domain BiPBP_C PF06832.12 EGB06508.1 - 0.00095 19.2 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family Ret2_MD PF18528.1 EGB06508.1 - 0.032 14.6 0.0 4.7 7.7 0.0 3.1 2 1 1 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain PQQ PF01011.21 EGB06508.1 - 0.048 13.6 2.3 6.1 7.0 0.0 4.2 4 1 0 4 4 4 0 PQQ enzyme repeat RCC1_2 PF13540.6 EGB06508.1 - 0.53 10.1 3.2 0.71 9.7 0.2 2.7 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Cpn60_TCP1 PF00118.24 EGB06509.1 - 1e-161 538.9 1.0 1.2e-161 538.7 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FtsJ PF01728.19 EGB06510.1 - 1.7e-60 204.1 0.1 1.9e-60 204.0 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EGB06510.1 - 0.0005 19.9 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB06510.1 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB06510.1 - 0.0022 18.6 0.6 0.02 15.6 0.2 2.6 2 1 0 2 2 2 1 Methyltransferase domain UPF0146 PF03686.13 EGB06510.1 - 0.05 13.5 0.1 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltr_RsmB-F PF01189.17 EGB06510.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CbiA PF01656.23 EGB06510.1 - 0.14 12.2 0.1 18 5.4 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain BON PF04972.17 EGB06510.1 - 6.1 7.2 7.9 0.25 11.7 1.2 2.1 3 0 0 3 3 3 0 BON domain Methyltransf_23 PF13489.6 EGB06511.1 - 1.1e-17 64.3 0.0 1.4e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB06511.1 - 1.9e-15 57.3 0.7 2.6e-15 56.9 0.7 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB06511.1 - 1.2e-14 54.9 0.1 1.7e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB06511.1 - 1.5e-14 54.4 0.5 2.3e-14 53.8 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB06511.1 - 8.7e-11 41.8 0.0 9.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB06511.1 - 3.1e-06 26.7 0.0 4.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGB06511.1 - 8.6e-06 25.3 0.4 1.1e-05 25.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB06511.1 - 2.3e-05 24.0 1.0 2.8e-05 23.7 1.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EGB06511.1 - 0.00021 21.0 0.0 0.00028 20.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 EGB06511.1 - 0.00099 18.8 0.1 0.0037 17.0 0.1 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EGB06511.1 - 0.0012 18.8 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EGB06511.1 - 0.0013 18.7 0.5 0.0018 18.3 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_9 PF08003.11 EGB06511.1 - 0.059 12.3 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 EGB06511.1 - 0.067 12.6 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 EGB06511.1 - 0.17 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 EGB06511.1 - 0.18 12.1 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TROVE PF05731.11 EGB06512.1 - 0.0031 16.6 0.1 0.0048 16.0 0.1 1.2 1 0 0 1 1 1 1 TROVE domain Ion_trans PF00520.31 EGB06512.1 - 0.0048 16.2 0.0 0.0079 15.4 0.0 1.4 1 0 0 1 1 1 1 Ion transport protein zf-TAZ PF02135.16 EGB06513.1 - 6e-11 42.6 9.2 6e-11 42.6 9.2 1.7 2 0 0 2 2 2 1 TAZ zinc finger Chloroa_b-bind PF00504.21 EGB06514.1 - 6.8e-32 111.2 0.2 1e-31 110.7 0.2 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NAPRTase PF04095.16 EGB06515.1 - 3.1e-61 207.0 0.0 4.1e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 EGB06515.1 - 1.7e-39 134.2 0.2 3.9e-39 133.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) Peptidase_M24 PF00557.24 EGB06516.1 - 1.5e-48 165.2 0.2 1.9e-48 164.9 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGB06516.1 - 2.1e-08 34.3 8.7 1.2e-07 31.9 8.7 2.3 1 1 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGB06516.1 - 0.01 15.9 1.0 0.01 15.9 1.0 2.7 3 0 0 3 3 3 0 MYND finger Peptidase_S28 PF05577.12 EGB06517.1 - 3.2e-74 250.3 0.0 4.9e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 PPR_long PF17177.4 EGB06517.1 - 1.9e-18 66.6 2.9 3.9e-16 59.1 2.9 2.2 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PRORP PF16953.5 EGB06517.1 - 3.3e-17 62.8 0.0 2.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Protein-only RNase P RNase_Zc3h12a PF11977.8 EGB06517.1 - 3.2e-06 27.0 0.0 5.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Peptidase_S9 PF00326.21 EGB06517.1 - 0.00032 20.2 0.5 0.0011 18.5 0.2 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGB06517.1 - 0.0013 18.0 0.1 0.0045 16.3 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB06517.1 - 0.0017 18.1 0.1 0.0037 16.9 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PPR_2 PF13041.6 EGB06517.1 - 0.0032 17.6 0.0 0.38 11.0 0.0 3.6 4 0 0 4 4 4 1 PPR repeat family Peptidase_S37 PF05576.11 EGB06517.1 - 0.0055 15.4 0.0 0.012 14.3 0.0 1.5 1 0 0 1 1 1 1 PS-10 peptidase S37 Esterase PF00756.20 EGB06517.1 - 0.023 14.3 0.1 0.059 13.0 0.1 1.6 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 EGB06517.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PPR PF01535.20 EGB06517.1 - 0.21 11.9 0.0 57 4.3 0.0 3.6 3 0 0 3 3 3 0 PPR repeat MOZ_SAS PF01853.18 EGB06519.1 - 1e-71 240.3 0.0 1.3e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGB06519.1 - 6.8e-16 57.6 1.3 1.6e-15 56.5 0.2 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGB06519.1 - 1.6e-11 43.9 0.1 2.9e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EGB06519.1 - 0.0066 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGB06519.1 - 0.015 15.5 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Myb_DNA-binding PF00249.31 EGB06520.1 - 3.3e-39 132.8 9.3 7.5e-13 48.5 0.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB06520.1 - 5.3e-30 103.5 0.3 5.1e-13 49.1 0.0 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB06520.1 - 0.0037 17.1 0.1 0.28 11.1 0.0 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EGB06520.1 - 0.0044 17.1 4.6 3.4 7.8 0.3 3.3 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EGB06520.1 - 0.012 16.0 5.3 0.2 12.0 0.1 3.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EGB06520.1 - 0.037 14.2 0.2 0.44 10.8 0.1 2.8 2 1 1 3 3 3 0 Rap1 Myb domain SLIDE PF09111.10 EGB06520.1 - 0.085 12.9 0.0 11 6.1 0.0 2.9 2 1 1 3 3 3 0 SLIDE Fe-S_biosyn PF01521.20 EGB06521.1 - 1.4e-12 47.8 0.0 5.7e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF21 PF01595.20 EGB06522.1 - 4.6e-29 101.4 2.6 6.2e-29 100.9 2.6 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain G-patch PF01585.23 EGB06523.1 - 6.8e-08 32.3 1.0 1.9e-07 30.9 1.0 1.8 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EGB06523.1 - 2.6e-06 27.7 0.5 6.1e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal GCFC PF07842.12 EGB06523.1 - 0.0026 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch_2 PF12656.7 EGB06523.1 - 0.0034 17.4 1.7 0.0092 16.0 0.6 2.3 2 0 0 2 2 2 1 G-patch domain PIH1 PF08190.12 EGB06524.1 - 4.7e-28 97.7 0.0 7.8e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain THF_DHG_CYH_C PF02882.19 EGB06524.1 - 3.7e-24 84.9 0.1 8.8e-24 83.6 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PIH1_CS PF18201.1 EGB06524.1 - 3.2e-16 59.6 0.0 6.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain Pterin_4a PF01329.19 EGB06524.1 - 2.1e-10 40.6 0.0 5.6e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase NMT1 PF09084.11 EGB06524.1 - 0.00019 21.5 0.1 0.02 14.8 0.0 2.9 2 1 0 2 2 2 1 NMT1/THI5 like THF_DHG_CYH PF00763.23 EGB06524.1 - 0.00067 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Kelch_3 PF13415.6 EGB06524.1 - 0.16 12.3 1.3 11 6.4 0.0 3.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Ion_trans PF00520.31 EGB06525.1 - 3.6e-15 55.9 0.2 5.8e-15 55.2 0.2 1.3 1 0 0 1 1 1 1 Ion transport protein Peptidase_A22B PF04258.13 EGB06525.1 - 9.4e-14 51.6 0.1 1.7e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Signal peptide peptidase cNMP_binding PF00027.29 EGB06525.1 - 1e-11 44.7 0.1 2.4e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGB06525.1 - 1.8e-11 43.8 2.7 5.3e-11 42.3 2.7 1.8 1 0 0 1 1 1 1 Ion channel CorA PF01544.18 EGB06525.1 - 1.1e-09 38.0 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1556 PF07590.11 EGB06525.1 - 3.6 8.0 5.6 0.87 9.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Peptidase_S10 PF00450.22 EGB06526.1 - 7.8e-101 338.5 0.0 9e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase SoxD PF04267.12 EGB06527.1 - 0.17 12.0 0.1 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family Peptidase_M22 PF00814.25 EGB06528.1 - 2.2e-74 250.6 0.3 2.4e-74 250.4 0.3 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EGB06528.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus MFS_1 PF07690.16 EGB06530.1 - 1.2e-08 34.2 43.9 9.5e-07 28.0 21.1 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily ELMO_CED12 PF04727.13 EGB06530.1 - 1.9e-06 28.1 0.0 5e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 ELMO/CED-12 family Sugar_tr PF00083.24 EGB06530.1 - 0.00047 19.1 8.5 0.00047 19.1 8.5 3.6 3 1 0 3 3 3 2 Sugar (and other) transporter PAS_9 PF13426.7 EGB06531.1 - 1.7e-20 73.2 0.0 1.9e-06 28.1 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 EGB06531.1 - 9.5e-07 28.8 0.0 0.0035 17.3 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 EGB06531.1 - 4.2e-06 26.7 0.1 0.11 12.5 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 EGB06531.1 - 7.8e-06 26.1 0.2 0.038 14.2 0.0 3.2 2 0 0 2 2 2 2 PAS fold DUF4328 PF14219.6 EGB06531.1 - 0.14 11.7 2.0 0.19 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) bZIP_1 PF00170.21 EGB06531.1 - 0.57 10.3 10.7 1.5 9.0 10.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor Mpp10 PF04006.12 EGB06531.1 - 4 5.8 8.4 7.3 4.9 8.4 1.3 1 0 0 1 1 1 0 Mpp10 protein PT PF04886.12 EGB06536.1 - 2.5e-13 49.3 43.1 0.00015 21.2 7.5 5.4 4 1 1 5 5 5 5 PT repeat Trypan_PARP PF05887.11 EGB06536.1 - 3.5 7.6 23.6 9.7e+02 -0.3 23.6 2.1 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMEM65 PF10507.9 EGB06537.1 - 9.5e-21 73.8 4.0 1e-20 73.7 4.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 zf-HIT PF04438.16 EGB06538.1 - 0.28 11.1 6.3 0.54 10.2 6.3 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-B_box PF00643.24 EGB06538.1 - 7.5 6.8 8.9 5.1 7.3 6.4 2.0 2 0 0 2 2 2 0 B-box zinc finger Thioredoxin PF00085.20 EGB06539.1 - 0.045 13.7 0.0 0.06 13.3 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin PFK PF00365.20 EGB06540.1 - 8.6e-56 189.3 0.2 1e-55 189.1 0.2 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 EGB06540.1 - 0.0073 15.9 0.6 0.02 14.5 0.2 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain A_thal_3526 PF09713.10 EGB06541.1 - 1e-23 83.3 0.2 9.6e-22 77.0 0.2 2.5 2 0 0 2 2 2 2 Plant protein 1589 of unknown function (A_thal_3526) GAF PF01590.26 EGB06541.1 - 1.4e-06 29.0 0.0 6.4e-06 26.8 0.0 2.2 1 0 0 1 1 1 1 GAF domain Aa_trans PF01490.18 EGB06542.1 - 3.6e-39 134.6 2.5 5.5e-39 134.0 2.5 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBR PF01485.21 EGB06542.1 - 1.4e-12 47.6 29.0 8.1e-08 32.4 7.3 3.9 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGB06542.1 - 0.0017 18.2 0.5 0.0017 18.2 0.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PEN-2 PF10251.9 EGB06543.1 - 7.1e-18 64.8 0.3 8.6e-18 64.6 0.3 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Abhydrolase_9_N PF15420.6 EGB06543.1 - 0.0044 17.0 0.3 0.0053 16.8 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus PMM PF03332.13 EGB06544.1 - 1.2e-97 326.0 0.0 1.4e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGB06544.1 - 3.2e-06 27.1 0.0 9.5e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGB06544.1 - 0.0033 17.0 0.0 0.29 10.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Alpha-amyl_C PF09071.10 EGB06544.1 - 0.048 13.5 0.0 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 Alpha-amylase, C terminal Pkinase PF00069.25 EGB06545.1 - 5.4e-51 173.5 0.0 7.5e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06545.1 - 2.3e-30 105.7 0.0 2.8e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB06545.1 - 6.4e-06 26.3 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB06545.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB06545.1 - 0.0091 15.4 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB06545.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGB06545.1 - 0.022 13.7 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Sulfotransfer_3 PF13469.6 EGB06546.1 - 7.6e-05 23.2 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family FAIM1 PF06905.13 EGB06547.1 - 0.0046 16.7 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) 2-Hacid_dh_C PF02826.19 EGB06548.1 - 6.7e-34 116.8 0.0 1.2e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGB06548.1 - 5.7e-15 55.1 0.0 7.8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGB06548.1 - 0.00019 21.6 0.0 0.00041 20.6 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EGB06548.1 - 0.0043 16.6 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EGB06548.1 - 0.055 13.3 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGB06548.1 - 0.079 13.5 0.0 0.2 12.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NifU PF01106.17 EGB06549.1 - 2.4e-21 75.7 0.0 2.5e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 NifU-like domain Peptidase_S8 PF00082.22 EGB06550.1 - 4.4e-28 98.4 10.2 3.2e-18 66.0 0.7 2.5 2 1 0 2 2 2 2 Subtilase family P_proprotein PF01483.20 EGB06550.1 - 1.6e-12 47.2 0.2 7.5e-12 45.1 0.1 2.0 2 0 0 2 2 2 1 Proprotein convertase P-domain MHYT PF03707.16 EGB06550.1 - 0.51 10.5 4.8 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Glyco_transf_9 PF01075.17 EGB06551.1 - 0.058 12.7 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Ank_2 PF12796.7 EGB06552.1 - 1.1e-17 64.4 0.0 4.4e-11 43.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB06552.1 - 4.2e-15 55.9 2.9 0.015 15.8 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB06552.1 - 2.9e-12 45.6 0.2 0.0074 16.7 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EGB06552.1 - 2.8e-10 40.2 1.3 0.0042 17.4 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB06552.1 - 9.1e-09 35.4 0.4 0.0023 18.3 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat OST-HTH PF12872.7 EGB06552.1 - 0.0035 17.1 0.0 0.009 15.8 0.0 1.7 2 0 0 2 2 2 1 OST-HTH/LOTUS domain DnaJ PF00226.31 EGB06552.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain CH PF00307.31 EGB06553.1 - 3.8e-21 75.3 0.0 4.6e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EGB06553.1 - 0.00036 20.7 0.0 0.00051 20.2 0.0 1.2 1 0 0 1 1 1 1 CDC24 Calponin PHD PF00628.29 EGB06554.1 - 2.6e-09 36.8 4.2 4.8e-09 36.0 4.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGB06554.1 - 0.11 12.1 1.0 0.26 10.9 0.3 1.9 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 EGB06554.1 - 0.46 10.8 4.3 0.5 10.7 2.3 2.0 2 0 0 2 2 2 0 C1 domain TPR_12 PF13424.6 EGB06555.1 - 4.5e-15 55.7 3.3 1.3e-07 31.8 0.0 4.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGB06555.1 - 1.5e-10 40.6 1.1 0.14 12.1 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB06555.1 - 7e-06 25.6 0.4 0.00034 20.1 0.1 2.2 1 1 1 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 EGB06555.1 - 0.0029 18.3 4.5 2.1 9.4 0.1 5.0 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06555.1 - 0.0033 17.3 0.2 45 4.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06555.1 - 0.12 12.5 9.4 4.1 7.8 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB06555.1 - 0.14 12.8 2.6 33 5.2 0.3 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06555.1 - 0.2 11.6 6.9 0.8 9.6 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06555.1 - 0.64 10.4 6.4 32 5.1 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_A22B PF04258.13 EGB06556.1 - 7e-41 140.6 0.1 8.3e-41 140.4 0.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EGB06556.1 - 0.0023 17.5 1.4 0.019 14.4 1.4 2.1 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease SGL PF08450.12 EGB06557.1 - 7.8e-05 22.4 1.0 0.021 14.4 0.0 3.3 3 1 0 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region SelR PF01641.18 EGB06558.1 - 1.8e-29 102.3 0.3 2.4e-29 101.9 0.3 1.1 1 0 0 1 1 1 1 SelR domain Zn_Tnp_IS1 PF03811.13 EGB06558.1 - 3 7.6 12.4 8.7 6.2 5.6 2.6 2 0 0 2 2 2 0 InsA N-terminal domain Nodulin-like PF06813.13 EGB06560.1 - 4.6e-25 88.5 8.2 5.1e-25 88.4 8.2 1.0 1 0 0 1 1 1 1 Nodulin-like zf-CSL PF05207.13 EGB06561.1 - 1.1e-16 60.3 0.3 1.3e-16 60.1 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 EGB06561.1 - 0.00021 21.3 0.2 0.00031 20.8 0.2 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Mpv17_PMP22 PF04117.12 EGB06562.1 - 2.8e-15 56.3 2.3 2.8e-15 56.3 2.3 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Wtap PF17098.5 EGB06563.1 - 3e-07 30.5 4.0 2.8e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 WTAP/Mum2p family Rootletin PF15035.6 EGB06563.1 - 0.026 14.6 3.2 0.028 14.5 1.0 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GIT_CC PF16559.5 EGB06563.1 - 0.056 13.3 1.3 0.18 11.7 1.3 1.9 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 EGB06563.1 - 0.66 10.0 5.4 0.74 9.8 0.7 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EGB06563.1 - 0.78 9.0 5.9 4.5 6.6 1.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 EGB06563.1 - 1.1 9.9 5.7 1 10.0 2.8 2.4 2 0 0 2 2 2 0 SlyX ZapB PF06005.12 EGB06563.1 - 1.3 9.5 7.3 0.31 11.5 3.6 1.8 2 0 0 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 EGB06563.1 - 1.3 9.3 4.8 6.1 7.1 0.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EGB06563.1 - 2.7 7.8 6.8 0.98 9.2 3.7 1.8 2 0 0 2 2 2 0 Septum formation initiator CENP-H PF05837.12 EGB06563.1 - 3.8 7.9 7.2 2.9 8.3 1.6 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) adh_short_C2 PF13561.6 EGB06564.1 - 1.3e-24 87.1 6.0 2.5e-14 53.4 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB06564.1 - 9.6e-18 64.3 3.8 3.5e-12 46.2 1.4 2.5 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 EGB06564.1 - 1.5e-08 34.7 0.5 2.4e-08 34.1 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB06564.1 - 0.018 14.5 0.3 0.024 14.1 0.3 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-MYND PF01753.18 EGB06565.1 - 4.2e-11 42.7 14.2 5.4e-11 42.4 14.2 1.1 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGB06565.1 - 0.085 13.2 8.0 0.17 12.2 8.0 1.5 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Sel1 PF08238.12 EGB06566.1 - 3.3e-13 49.8 7.0 3.7e-06 27.4 0.4 3.3 3 1 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.6 EGB06566.1 - 0.82 10.4 3.9 7.2 7.5 0.5 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Coprogen_oxidas PF01218.18 EGB06567.1 - 1.2e-58 198.2 0.0 1.4e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Pyr_redox_2 PF07992.14 EGB06568.1 - 9.3e-07 28.4 5.0 0.007 15.6 0.5 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB06568.1 - 0.019 15.2 0.1 0.056 13.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EGB06568.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 EGB06569.1 - 0.00096 19.8 0.0 0.0019 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB06569.1 - 0.0026 17.6 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB06569.1 - 0.092 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TIP41 PF04176.13 EGB06570.1 - 1.4e-09 37.7 0.2 2e-09 37.2 0.2 1.2 1 0 0 1 1 1 1 TIP41-like family PQQ_2 PF13360.6 EGB06570.1 - 0.00044 19.9 12.6 0.00044 19.9 12.6 2.2 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 EGB06570.1 - 0.00099 18.9 2.2 0.0067 16.3 0.0 3.2 3 1 1 4 4 4 1 PQQ enzyme repeat WD40 PF00400.32 EGB06570.1 - 0.067 14.1 0.4 2.7 9.0 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Mito_carr PF00153.27 EGB06571.1 - 2.5e-54 181.2 8.8 5.8e-18 64.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EGB06571.1 - 2.8e-19 67.2 0.0 0.00013 21.3 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB06571.1 - 7.7e-18 62.8 0.3 0.00029 20.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGB06571.1 - 1.2e-17 64.1 0.6 3.9e-09 36.8 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB06571.1 - 5.1e-12 44.7 0.2 0.0002 20.7 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EGB06571.1 - 3.3e-06 26.9 0.8 0.012 15.5 0.1 4.0 2 1 2 4 4 4 1 EF-hand domain pair EutK_C PF16365.5 EGB06571.1 - 0.0013 18.8 0.3 1.2 9.2 0.2 2.7 2 0 0 2 2 2 2 Ethanolamine utilization protein EutK C-terminus EF-hand_9 PF14658.6 EGB06571.1 - 0.049 14.0 0.1 2.9 8.3 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB06571.1 - 0.1 13.0 0.2 6.2 7.2 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PAS_9 PF13426.7 EGB06572.1 - 3.2e-15 56.2 0.0 3.6e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGB06572.1 - 5.4e-06 26.4 0.0 6.9e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGB06572.1 - 0.00021 21.5 0.0 0.00024 21.3 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EGB06572.1 - 0.00039 20.6 0.0 0.00045 20.4 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EGB06572.1 - 0.054 13.5 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 PAS domain U-box PF04564.15 EGB06573.1 - 1.4e-16 60.4 0.0 2.3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 U-box domain Ank_4 PF13637.6 EGB06573.1 - 1.7e-05 25.2 0.0 7e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-Nse PF11789.8 EGB06573.1 - 0.00088 19.1 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ank_5 PF13857.6 EGB06573.1 - 0.088 13.2 0.3 0.51 10.7 0.0 2.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) zf-PARP PF00645.18 EGB06574.1 - 0.055 14.3 0.0 0.14 13.0 0.0 1.8 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Evr1_Alr PF04777.13 EGB06576.1 - 2.8e-13 50.2 0.0 3.2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Arm PF00514.23 EGB06577.1 - 2.1e-14 53.0 4.9 1.2e-05 25.1 0.2 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat 2OG-FeII_Oxy_3 PF13640.6 EGB06577.1 - 1.7e-13 51.2 0.0 4.2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CRAL_TRIO PF00650.20 EGB06577.1 - 2.4e-08 33.9 0.0 5.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain 2OG-FeII_Oxy_4 PF13661.6 EGB06577.1 - 2.6e-06 28.0 0.0 7.3e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HEAT PF02985.22 EGB06577.1 - 0.0015 18.6 0.0 1.8 9.0 0.0 4.1 3 0 0 3 3 2 1 HEAT repeat FliJ PF02050.16 EGB06577.1 - 0.04 14.1 15.9 0.16 12.2 15.9 2.0 1 0 0 1 1 1 0 Flagellar FliJ protein RTP1_C1 PF10363.9 EGB06577.1 - 0.072 13.3 0.0 4.1 7.6 0.0 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Filament PF00038.21 EGB06577.1 - 0.09 12.3 16.2 0.18 11.3 16.2 1.5 1 0 0 1 1 1 0 Intermediate filament protein Peptidase_M3_N PF08439.10 EGB06577.1 - 0.11 12.8 0.2 1.1 9.5 0.6 2.3 2 0 0 2 2 2 0 Oligopeptidase F Leu_zip PF15294.6 EGB06577.1 - 0.28 10.7 13.4 0.53 9.8 13.4 1.4 1 0 0 1 1 1 0 Leucine zipper GRP PF07172.11 EGB06577.1 - 0.34 11.6 7.8 1.1 10.0 7.8 1.8 1 0 0 1 1 1 0 Glycine rich protein family Exonuc_VII_L PF02601.15 EGB06577.1 - 0.61 9.6 7.7 1.6 8.2 7.7 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Perilipin PF03036.16 EGB06577.1 - 0.63 9.0 8.7 1.7 7.6 8.7 1.7 1 0 0 1 1 1 0 Perilipin family Nup88 PF10168.9 EGB06577.1 - 2.7 5.7 15.3 4.7 4.9 15.3 1.3 1 0 0 1 1 1 0 Nuclear pore component FAM76 PF16046.5 EGB06577.1 - 4.5 6.5 17.9 21 4.4 18.1 1.9 1 1 0 1 1 1 0 FAM76 protein DUF5082 PF16888.5 EGB06577.1 - 5.1 7.4 11.3 10 6.4 11.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 EGB06577.1 - 5.3 7.1 5.8 1.1 9.2 1.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EGB06577.1 - 7.3 6.8 8.6 20 5.4 8.6 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PAP_fibrillin PF04755.12 EGB06578.1 - 4.1e-08 33.4 0.1 4.7e-06 26.7 0.4 3.3 2 1 0 2 2 2 1 PAP_fibrillin DOPA_dioxygen PF08883.11 EGB06578.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family TMCO5 PF14992.6 EGB06578.1 - 9.7 5.7 7.1 20 4.6 7.1 1.4 1 0 0 1 1 1 0 TMCO5 family PAP_fibrillin PF04755.12 EGB06579.1 - 7.9e-11 42.3 1.1 1.2e-07 31.9 1.1 3.0 1 1 0 1 1 1 1 PAP_fibrillin F-box-like_2 PF13013.6 EGB06579.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.2 1 0 0 1 1 1 0 F-box-like domain SNF2_N PF00176.23 EGB06580.1 - 1.2e-51 175.5 0.0 1.8e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGB06580.1 - 2e-12 47.4 0.0 4.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGB06580.1 - 6.7e-09 36.1 0.0 2.4e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB06580.1 - 2.1e-05 24.4 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pol_alpha_B_N PF08418.10 EGB06580.1 - 0.00017 21.6 0.8 0.00041 20.4 0.8 1.6 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DUF2075 PF09848.9 EGB06580.1 - 0.00053 19.3 0.0 0.00095 18.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Bromodomain PF00439.25 EGB06580.1 - 0.011 15.7 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Bromodomain AAA_22 PF13401.6 EGB06580.1 - 0.045 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.6 EGB06581.1 - 2e-52 173.7 32.8 4e-11 42.4 0.2 8.0 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06581.1 - 2.2e-50 168.9 26.5 4.3e-13 49.4 0.4 7.0 1 1 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06581.1 - 4.7e-15 54.4 26.4 0.078 13.0 0.5 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06581.1 - 4.8e-11 42.0 11.0 0.25 11.7 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06581.1 - 3.6e-08 32.9 20.8 0.24 11.6 0.2 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06581.1 - 5.7e-08 32.2 15.1 0.43 10.5 0.2 6.8 6 2 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06581.1 - 3.8e-07 30.4 23.5 0.43 11.5 0.1 6.8 5 2 2 7 7 7 2 Tetratricopeptide repeat DUF1955 PF09205.10 EGB06581.1 - 0.00012 21.9 0.8 13 5.5 0.1 5.3 1 1 5 6 6 6 0 Domain of unknown function (DUF1955) TPR_6 PF13174.6 EGB06581.1 - 0.00015 22.2 10.1 3.1 8.6 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF2225 PF09986.9 EGB06581.1 - 0.00023 21.0 0.1 8.3 6.1 0.0 4.2 1 1 2 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) Mob_Pre PF01076.19 EGB06581.1 - 0.0017 18.2 0.0 22 4.8 0.0 4.2 2 2 1 4 4 4 0 Plasmid recombination enzyme DUF5471 PF17565.2 EGB06581.1 - 0.003 17.8 15.1 1.4 9.2 0.4 5.8 1 1 5 6 6 6 1 Family of unknown function (DUF5471) SPO22 PF08631.10 EGB06581.1 - 0.01 15.4 0.0 2.5 7.5 0.0 2.9 1 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF4807 PF16065.5 EGB06581.1 - 0.022 14.4 0.1 93 2.7 0.0 4.7 3 2 2 6 6 6 0 Domain of unknown function (DUF4807) TPR_17 PF13431.6 EGB06581.1 - 0.044 14.2 8.7 28 5.4 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGB06581.1 - 0.046 14.3 19.5 4.9 8.1 0.1 7.3 6 3 1 7 7 7 0 Tetratricopeptide repeat Trp_repressor PF01371.19 EGB06581.1 - 0.1 12.7 0.0 11 6.2 0.0 3.3 2 2 3 5 5 5 0 Trp repressor protein SMBP PF16785.5 EGB06581.1 - 0.22 11.7 1.3 10 6.4 1.3 2.4 1 1 0 1 1 1 0 Small metal-binding protein TPR_11 PF13414.6 EGB06581.1 - 2.3 8.0 10.8 27 4.6 0.1 5.1 5 0 0 5 5 5 0 TPR repeat TPR_16 PF13432.6 EGB06581.1 - 4.6 8.0 25.0 3.7 8.3 4.6 5.0 3 3 2 5 5 5 0 Tetratricopeptide repeat MRFAP1 PF15155.6 EGB06581.1 - 6.2 7.4 8.1 23 5.5 0.1 3.9 2 1 2 4 4 4 0 MORF4 family-associated protein1 PCI PF01399.27 EGB06582.1 - 0.00085 19.8 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 PCI domain PhyH PF05721.13 EGB06584.1 - 3.7e-09 37.2 0.0 2.5e-08 34.5 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EGB06584.1 - 0.088 11.6 0.0 0.66 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 EGB06584.1 - 0.097 13.6 0.0 0.24 12.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EGB06584.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PMSR PF01625.21 EGB06585.1 - 2.1e-44 151.4 0.0 2.7e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Glutaredoxin PF00462.24 EGB06586.1 - 9.9e-18 64.1 0.0 1.2e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EGB06586.1 - 0.0018 18.7 0.0 0.0021 18.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB06586.1 - 0.0056 17.0 0.0 0.007 16.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 EGB06586.1 - 0.042 14.3 0.2 0.26 11.8 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Sof1 PF04158.14 EGB06587.1 - 6.9e-23 80.7 6.5 1.6e-22 79.5 6.5 1.7 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EGB06587.1 - 1.1e-15 57.7 9.2 0.0062 17.4 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat adh_short_C2 PF13561.6 EGB06588.1 - 1.1e-53 182.2 5.5 2.1e-52 178.0 5.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB06588.1 - 1.7e-49 168.0 2.4 2.1e-49 167.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB06588.1 - 3.7e-12 46.5 1.7 5.7e-12 45.9 1.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB06588.1 - 5.7e-08 32.5 0.4 1.5e-07 31.1 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGB06588.1 - 2.8e-05 24.4 0.3 4.7e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EGB06588.1 - 3.3e-05 23.2 0.2 4.1e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EGB06588.1 - 5.8e-05 23.1 0.4 0.00013 21.9 0.4 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EGB06588.1 - 0.001 18.6 0.1 0.0036 16.7 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGB06588.1 - 0.0025 16.9 0.4 0.0049 15.9 0.4 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EGB06588.1 - 0.0034 17.6 0.2 0.0076 16.5 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_25 PF13649.6 EGB06588.1 - 0.015 16.0 0.0 0.03 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.13 EGB06588.1 - 0.05 13.2 0.6 0.076 12.6 0.6 1.3 1 0 0 1 1 1 0 NmrA-like family UTP15_C PF09384.10 EGB06589.1 - 2.2e-36 124.8 0.0 3.1e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal ANAPC4_WD40 PF12894.7 EGB06589.1 - 3.2e-07 30.6 0.0 0.0001 22.6 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGB06589.1 - 1.8e-06 28.5 10.3 0.64 11.0 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat MMR_HSR1_Xtn PF16897.5 EGB06590.1 - 1.7e-37 127.7 0.0 3.1e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGB06590.1 - 8e-20 71.0 0.1 2.4e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EGB06590.1 - 7.2e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGB06590.1 - 4.7e-09 36.0 0.0 1.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGB06590.1 - 0.0047 17.0 4.5 0.17 12.0 0.0 2.8 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.16 EGB06590.1 - 0.046 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 EGB06590.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Na_Ca_ex PF01699.24 EGB06591.1 - 4.8e-43 146.7 34.1 1.9e-23 83.1 17.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 EGB06591.1 - 1.2e-29 102.5 0.7 2.1e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Calx-beta domain Sel1 PF08238.12 EGB06593.1 - 1.8e-39 133.3 25.3 3.6e-08 33.8 0.1 8.6 8 1 0 8 8 8 7 Sel1 repeat TPR_10 PF13374.6 EGB06593.1 - 0.00042 20.1 0.2 0.00042 20.1 0.2 7.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06593.1 - 0.0019 18.5 14.2 0.0074 16.5 0.4 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB06593.1 - 0.028 14.8 0.1 11 6.6 0.0 3.0 2 1 1 3 3 3 0 B12 binding domain Smac_DIABLO PF09057.10 EGB06593.1 - 0.058 12.7 0.1 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases TPR_1 PF00515.28 EGB06593.1 - 0.074 12.9 0.0 0.074 12.9 0.0 6.9 10 0 0 10 10 9 0 Tetratricopeptide repeat VIT PF08487.10 EGB06593.1 - 0.082 13.1 1.2 47 4.2 0.0 4.0 4 0 0 4 4 4 0 Vault protein inter-alpha-trypsin domain TPR_2 PF07719.17 EGB06593.1 - 0.39 10.9 0.1 0.39 10.9 0.1 8.5 10 0 0 10 10 10 0 Tetratricopeptide repeat RHH_1 PF01402.21 EGB06593.1 - 0.51 10.4 2.8 10 6.2 0.1 3.3 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family TPR_7 PF13176.6 EGB06593.1 - 0.98 9.6 14.6 11 6.4 0.0 6.5 6 1 0 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 EGB06593.1 - 3.3 8.9 5.9 2.7e+02 3.2 0.0 5.2 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.6 EGB06593.1 - 6.1 7.3 16.1 3.6 8.0 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat UDPGP PF01704.18 EGB06594.1 - 4.1e-12 45.5 0.0 6.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pkinase PF00069.25 EGB06595.1 - 6.5e-53 179.8 0.0 7.4e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06595.1 - 2.7e-27 95.7 0.0 3e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB06595.1 - 0.00023 20.2 0.0 0.00028 20.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB06595.1 - 0.00044 19.7 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB06595.1 - 0.00077 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB06595.1 - 0.0014 18.6 0.1 0.0026 17.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGB06595.1 - 0.03 13.9 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Aha1_N PF09229.11 EGB06596.1 - 1.8e-15 57.4 0.0 2.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Fer2_3 PF13085.6 EGB06597.1 - 2e-32 111.4 0.0 3.1e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGB06597.1 - 2.8e-09 37.4 5.6 2.8e-09 37.4 5.6 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGB06597.1 - 3.6e-07 30.5 7.9 3.6e-07 30.5 7.9 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGB06597.1 - 9.3e-07 28.9 3.0 9.3e-07 28.9 3.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGB06597.1 - 0.00075 19.4 1.8 0.00075 19.4 1.8 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EGB06597.1 - 0.011 15.9 0.3 0.23 11.6 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGB06597.1 - 0.035 14.7 7.7 0.035 14.7 7.7 2.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain DUF5433 PF17498.2 EGB06597.1 - 0.18 12.1 1.6 0.65 10.3 1.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5433) Fer4_9 PF13187.6 EGB06597.1 - 0.56 10.4 12.9 0.12 12.5 7.3 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain PSII_BNR PF14870.6 EGB06598.1 - 5.1e-130 433.1 2.5 6e-130 432.9 2.5 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 EGB06598.1 - 4.1e-08 32.0 4.9 1.9 8.8 0.0 5.6 6 0 0 6 6 6 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EGB06598.1 - 8.3e-05 21.6 0.1 0.068 11.9 0.0 3.1 2 1 0 3 3 3 2 Sortilin, neurotensin receptor 3, TAT_signal PF10518.9 EGB06598.1 - 0.069 13.0 14.3 0.04 13.8 7.3 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 EGB06598.1 - 2.8 7.4 10.2 0.14 11.5 3.7 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal IDO PF01231.18 EGB06600.1 - 2.1e-66 224.5 0.0 7.2e-46 156.9 0.0 3.4 3 1 0 3 3 3 3 Indoleamine 2,3-dioxygenase DnaJ PF00226.31 EGB06601.1 - 2.8e-19 69.0 0.0 3.1e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain zf-MYND PF01753.18 EGB06602.1 - 8e-05 22.6 9.9 0.00017 21.6 9.9 1.6 1 0 0 1 1 1 1 MYND finger DUF3458_C PF17432.2 EGB06602.1 - 0.049 13.0 0.2 0.83 9.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3458_C) ARM repeats zf-C6H2 PF15801.5 EGB06602.1 - 0.8 10.1 5.9 2 8.8 5.9 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding THF_DHG_CYH_C PF02882.19 EGB06603.1 - 2.4e-65 218.7 2.3 4.3e-65 217.9 2.3 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGB06603.1 - 4.4e-38 130.1 0.2 7e-38 129.5 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain FTHFS PF01268.19 EGB06604.1 - 2.2e-58 197.9 0.4 2.4e-58 197.7 0.4 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 EGB06604.1 - 0.005 16.9 0.9 0.0082 16.2 0.9 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Lzipper-MIP1 PF14389.6 EGB06605.1 - 0.0046 17.2 0.0 0.0081 16.4 0.0 1.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF4391 PF14335.6 EGB06605.1 - 0.12 12.1 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF4140 PF13600.6 EGB06605.1 - 0.38 11.2 4.5 0.78 10.2 0.3 2.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1192 PF06698.11 EGB06605.1 - 9 6.4 9.1 1.8 8.7 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) START PF01852.19 EGB06606.1 - 1.2e-08 34.7 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 START domain MiAMP1 PF09117.10 EGB06606.1 - 0.027 14.7 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 MiAMP1 AMP-binding PF00501.28 EGB06607.1 - 6.3e-78 262.2 0.0 8.2e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB06607.1 - 1.5e-16 61.1 4.2 1.5e-16 61.1 4.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGB06607.1 - 3.7e-11 42.8 0.1 8e-11 41.7 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus ThiF PF00899.21 EGB06608.1 - 1.2e-14 54.2 0.3 2.3e-14 53.3 0.3 1.4 1 0 0 1 1 1 1 ThiF family PRiA4_ORF3 PF07929.11 EGB06608.1 - 2.2e-14 53.5 0.0 4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 EGB06608.1 - 1.8e-10 40.7 13.7 1.8e-10 40.7 13.7 2.0 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EGB06608.1 - 2.1 8.7 8.0 4.9 7.5 8.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HMG_box PF00505.19 EGB06609.1 - 5.2e-09 36.4 1.6 9.4e-09 35.6 1.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box INCENP_ARK-bind PF03941.15 EGB06609.1 - 1.6e-06 28.0 0.2 2.8e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region WXG100 PF06013.12 EGB06611.1 - 0.3 11.3 0.1 0.3 11.3 0.1 3.8 4 1 0 4 4 4 0 Proteins of 100 residues with WXG GxGYxYP_C PF14323.6 EGB06612.1 - 1.7e-13 51.0 0.1 3.1e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 GxGYxYP putative glycoside hydrolase C-terminal domain GxGYxYP_N PF16216.5 EGB06612.1 - 9.5e-05 22.7 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Pkinase PF00069.25 EGB06613.1 - 2.5e-50 171.3 0.0 3.9e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06613.1 - 3.7e-27 95.3 0.0 7.4e-27 94.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB06613.1 - 7.6e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB06613.1 - 0.00023 20.6 0.1 0.00056 19.3 0.1 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB06613.1 - 0.0036 17.2 0.1 0.024 14.6 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CBP_BcsQ PF06564.12 EGB06613.1 - 0.095 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Got1 PF04178.12 EGB06614.1 - 9.1e-33 113.0 9.9 2.3e-32 111.7 9.7 1.6 1 1 1 2 2 2 2 Got1/Sft2-like family TP_methylase PF00590.20 EGB06615.1 - 2e-17 63.8 0.3 7.8e-17 61.9 0.3 1.8 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MFS_1 PF07690.16 EGB06616.1 - 4.1e-26 91.7 19.8 6.9e-25 87.7 10.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGB06616.1 - 0.0057 15.6 0.7 0.0057 15.6 0.7 2.5 2 1 0 2 2 2 1 MFS_1 like family IspA PF04279.15 EGB06616.1 - 0.16 12.1 2.3 0.43 10.7 1.9 2.0 2 0 0 2 2 2 0 Intracellular septation protein A DUF2842 PF11003.8 EGB06616.1 - 5.7 7.3 9.3 1.5 9.1 1.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2842) cNMP_binding PF00027.29 EGB06617.1 - 5.2e-15 55.3 0.1 1.1e-14 54.2 0.1 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain ANF_receptor PF01094.28 EGB06618.1 - 1.1e-21 77.3 0.6 2.2e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region Ephrin_rec_like PF07699.13 EGB06618.1 - 3.8 7.4 24.4 0.02 14.7 2.7 4.0 2 1 2 4 4 4 0 Putative ephrin-receptor like Tetraspanin PF00335.20 EGB06618.1 - 5.6 6.6 7.4 8.4 6.0 0.6 2.5 2 0 0 2 2 2 0 Tetraspanin family TLD PF07534.16 EGB06619.1 - 2e-05 24.8 0.0 2.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 TLD Chorismate_bind PF00425.18 EGB06620.1 - 2.8e-61 207.3 0.0 4e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EGB06620.1 - 6.4e-35 120.6 0.0 9e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGB06620.1 - 2.6e-09 37.2 0.4 2.7e-08 33.8 0.4 2.2 1 1 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.13 EGB06620.1 - 5.7e-07 29.8 0.0 1e-05 25.8 0.0 2.8 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Carboxyl_trans PF01039.22 EGB06621.1 - 4.6e-142 474.1 0.0 6.7e-142 473.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 EGB06621.1 - 1.9e-69 234.7 0.0 2.6e-67 227.7 0.0 2.7 1 1 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 EGB06621.1 - 1.6e-50 171.6 0.0 3e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGB06621.1 - 5.3e-31 107.4 1.0 9.5e-31 106.6 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGB06621.1 - 6e-22 77.8 0.0 1.4e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGB06621.1 - 4.7e-13 48.8 1.6 1e-12 47.7 0.3 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EGB06621.1 - 2.2e-05 24.6 0.0 7.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 EGB06621.1 - 0.0032 17.0 0.0 0.022 14.3 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EGB06621.1 - 0.0041 16.9 0.0 0.18 11.6 0.0 2.8 2 0 0 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EGB06621.1 - 0.0059 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGB06621.1 - 0.16 11.7 0.0 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon BKACE PF05853.12 EGB06622.1 - 2.5e-83 279.6 0.0 2.9e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme TTL PF03133.15 EGB06623.1 - 4.5e-24 85.1 0.0 6.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ABC_tran PF00005.27 EGB06624.1 - 1.5e-32 112.9 0.0 3.3e-32 111.9 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 EGB06624.1 - 4e-29 102.1 0.1 5.4e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGB06624.1 - 1.1e-07 31.5 0.0 2.6e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB06624.1 - 0.00018 22.0 0.2 0.00039 20.8 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB06624.1 - 0.0012 18.7 0.0 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB06624.1 - 0.0013 18.4 0.1 0.0034 17.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB06624.1 - 0.002 18.4 0.1 0.023 15.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGB06624.1 - 0.0029 17.5 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EGB06624.1 - 0.0035 16.9 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGB06624.1 - 0.0085 16.3 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGB06624.1 - 0.019 15.0 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 EGB06624.1 - 0.059 12.2 0.4 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 EGB06624.1 - 0.072 13.6 0.0 0.19 12.2 0.1 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB06624.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EGB06624.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.25 EGB06624.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 EGB06624.1 - 0.12 12.3 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3584 PF12128.8 EGB06624.1 - 0.16 9.5 0.1 0.22 9.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DnaJ_C PF01556.18 EGB06625.1 - 7.8e-37 126.6 0.0 1.2e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB06625.1 - 3e-21 75.3 0.2 6.3e-21 74.3 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGB06625.1 - 4.2e-13 49.4 16.0 8.4e-13 48.5 16.0 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGB06625.1 - 0.086 12.8 18.8 0.55 10.2 4.0 3.5 2 1 3 5 5 5 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 EGB06625.1 - 0.68 10.0 10.1 1.6 8.9 9.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EGB06625.1 - 0.91 9.6 7.1 2.7 8.0 7.1 1.8 1 1 0 1 1 1 0 zinc-ribbons TackOD1 PF18551.1 EGB06625.1 - 1 9.0 7.2 0.57 9.8 1.4 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-CHY PF05495.12 EGB06625.1 - 6.9 7.2 7.1 1.2 9.6 2.1 2.0 1 1 1 2 2 2 0 CHY zinc finger RseC_MucC PF04246.12 EGB06625.1 - 9.9 6.1 10.0 1.4 8.9 2.1 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC GHMP_kinases_N PF00288.26 EGB06626.1 - 3.6e-05 23.9 0.1 8.4e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Dimer_Tnp_hAT PF05699.14 EGB06626.1 - 0.00018 21.2 0.2 0.00035 20.3 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ribosomal_L13e PF01294.18 EGB06627.1 - 5.8e-61 205.5 1.8 6.4e-61 205.3 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e FlhE PF06366.13 EGB06628.1 - 0.024 14.6 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 Flagellar protein FlhE Kinesin PF00225.23 EGB06629.1 - 5.9e-94 314.7 0.0 7.1e-94 314.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB06629.1 - 5.4e-18 65.4 0.0 8.9e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding PCO_ADO PF07847.12 EGB06630.1 - 2.4e-29 102.2 0.0 3.2e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 EGB06630.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Cupin domain CDO_I PF05995.12 EGB06630.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I DNA_gyraseB PF00204.25 EGB06631.1 - 9.2e-46 155.5 0.0 1.3e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 EGB06631.1 - 6.2e-26 90.4 0.1 1.1e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 EGB06631.1 - 1.2e-16 61.2 0.0 4.4e-16 59.4 0.0 2.0 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGB06631.1 - 2e-14 53.7 0.0 1e-13 51.4 0.0 2.1 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 EGB06631.1 - 0.0064 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.27 EGB06632.1 - 2.2e-45 152.5 0.2 6.7e-15 54.8 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein FAD_binding_3 PF01494.19 EGB06634.1 - 7.2e-20 71.5 2.2 2.5e-10 40.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGB06634.1 - 1.2e-08 35.0 8.1 2.2e-05 24.2 1.6 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB06634.1 - 1.5e-05 24.3 1.8 0.0003 20.0 0.4 2.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB06634.1 - 0.00034 20.0 0.0 0.0015 17.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB06634.1 - 0.00083 19.5 0.1 0.0035 17.5 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGB06634.1 - 0.0013 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB06634.1 - 0.0016 17.2 0.1 0.019 13.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 EGB06634.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 EGB06634.1 - 0.0094 15.0 0.3 0.027 13.5 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EGB06634.1 - 0.064 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Peptidase_C54 PF03416.19 EGB06635.1 - 1.7e-50 172.0 0.0 7.6e-38 130.5 0.0 2.8 2 1 0 2 2 2 2 Peptidase family C54 Peptidase_C78 PF07910.13 EGB06635.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C78 Rep_fac-A_C PF08646.10 EGB06636.1 - 2.8e-43 147.2 5.7 6.7e-42 142.7 6.4 2.2 2 0 0 2 2 2 1 Replication factor-A C terminal domain DUF2838 PF10998.8 EGB06636.1 - 9.2e-36 122.5 0.4 1.7e-35 121.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) REPA_OB_2 PF16900.5 EGB06636.1 - 2.7e-23 81.7 0.0 7.9e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 EGB06636.1 - 7.6e-20 70.8 0.0 1.4e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EGB06636.1 - 1.5e-10 40.9 0.1 8.8e-08 32.0 0.0 3.0 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Ureidogly_lyase PF04115.12 EGB06636.1 - 6.6e-06 26.0 0.0 2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Ureidoglycolate lyase NAD_binding_1 PF00175.21 EGB06637.1 - 3.9e-22 79.0 0.0 5.2e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGB06637.1 - 7.2e-15 55.2 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGB06637.1 - 0.035 14.2 0.0 3 8.0 0.0 2.1 1 1 1 2 2 2 0 Ferric reductase NAD binding domain UCH PF00443.29 EGB06638.1 - 1e-30 107.1 0.0 1.6e-14 54.1 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB06638.1 - 2.6e-08 33.8 0.0 1.1e-05 25.3 0.1 2.0 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGB06638.1 - 0.13 11.7 0.0 8.3 5.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ureidogly_lyase PF04115.12 EGB06639.1 - 2.5e-07 30.6 0.0 1.4e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Ureidoglycolate lyase UCH PF00443.29 EGB06640.1 - 2e-33 116.0 0.0 3.4e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FAD_binding_6 PF00970.24 EGB06640.1 - 1.3e-13 51.1 0.0 2.7e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain UCH_1 PF13423.6 EGB06640.1 - 0.00023 20.9 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGB06640.1 - 0.0022 18.6 0.0 0.0044 17.6 0.0 1.5 1 0 0 1 1 1 1 DUSP domain zf-MYND PF01753.18 EGB06641.1 - 6.2e-10 39.0 16.8 1.7e-09 37.6 16.8 1.8 1 0 0 1 1 1 1 MYND finger PSK_trans_fac PF07704.11 EGB06641.1 - 0.083 13.7 1.8 1.1 10.1 0.0 3.2 2 1 0 2 2 2 0 Rv0623-like transcription factor Sfi1 PF08457.10 EGB06641.1 - 0.088 11.3 0.3 0.13 10.7 0.3 1.2 1 0 0 1 1 1 0 Sfi1 spindle body protein B9-C2 PF07162.11 EGB06642.1 - 6.1e-48 163.2 0.0 7e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Complex1_LYR PF05347.15 EGB06643.1 - 1e-08 35.1 1.6 1.3e-08 34.8 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Herpes_DNAp_acc PF04929.12 EGB06643.1 - 5.8 5.8 7.0 6.1 5.7 7.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RIIa PF02197.17 EGB06644.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit COMM_domain PF07258.14 EGB06645.1 - 3.4e-06 27.1 0.0 4.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 COMM domain Bromodomain PF00439.25 EGB06646.1 - 4.9e-13 48.9 0.0 5.6e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.32 EGB06647.1 - 2.7e-24 84.9 16.8 3.3e-08 34.0 1.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06647.1 - 2.7e-06 27.6 0.4 0.64 10.4 0.0 3.2 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB06647.1 - 0.015 14.0 0.4 3.5 6.1 0.0 3.2 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGB06647.1 - 0.022 13.3 0.0 0.14 10.7 0.0 1.9 1 1 0 2 2 2 0 Cytochrome D1 heme domain Marek_SORF3 PF07153.11 EGB06647.1 - 0.065 12.6 0.1 0.2 11.0 0.1 1.7 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein Ge1_WD40 PF16529.5 EGB06647.1 - 0.39 9.6 3.8 6.2 5.7 0.1 3.2 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CKS PF01111.19 EGB06648.1 - 7.4e-34 115.8 1.4 9.6e-34 115.5 1.4 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit AMP-binding PF00501.28 EGB06649.1 - 1.4e-30 106.3 0.0 2.6e-30 105.4 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Acyl_transf_3 PF01757.22 EGB06649.1 - 2.8e-06 26.7 35.5 4.9e-06 25.8 35.2 1.6 1 1 0 1 1 1 1 Acyltransferase family PP-binding PF00550.25 EGB06649.1 - 5.2e-06 26.7 0.1 1e-05 25.8 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGB06649.1 - 0.0041 18.1 0.1 0.015 16.2 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_4 PF12799.7 EGB06650.1 - 9.9e-18 64.0 3.5 0.0035 17.7 0.1 6.2 2 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB06650.1 - 2e-15 55.5 17.7 0.001 18.9 0.1 9.7 9 1 0 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.6 EGB06650.1 - 1.4e-09 37.6 2.8 0.26 11.1 0.2 4.9 3 2 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 EGB06650.1 - 0.00041 20.5 5.0 2.6 8.9 0.0 6.3 6 2 0 6 6 6 1 Leucine Rich Repeat Nudc_N PF14050.6 EGB06650.1 - 0.11 12.5 0.1 43 4.2 0.0 3.6 5 0 0 5 5 5 0 N-terminal conserved domain of Nudc. Transp_inhibit PF18791.1 EGB06650.1 - 0.12 11.9 5.0 30 4.2 0.0 5.7 7 0 0 7 7 7 0 Transport inhibitor response 1 protein domain Sulfolobus_pRN PF05584.11 EGB06650.1 - 0.23 11.5 5.1 18 5.5 0.0 4.2 3 1 3 6 6 6 0 Sulfolobus plasmid regulatory protein SAM_Ste50p PF09235.10 EGB06650.1 - 5.1 7.4 16.0 4.8 7.5 2.2 4.2 4 1 1 5 5 5 0 Ste50p, sterile alpha motif Bact_lectin PF18483.1 EGB06651.1 - 5.5e-16 59.2 0.0 9.8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EGB06651.1 - 3e-11 43.3 0.0 5e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain DUF393 PF04134.12 EGB06651.1 - 1.8e-06 29.3 0.4 7.1e-06 27.3 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF393 TIG PF01833.24 EGB06651.1 - 3.8e-05 23.7 0.0 9.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain fn3 PF00041.21 EGB06651.1 - 0.093 13.1 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain PLAC8 PF04749.17 EGB06654.1 - 1.7e-08 35.3 16.9 1.7e-08 35.3 16.9 2.3 2 0 0 2 2 2 2 PLAC8 family Myosin_head PF00063.21 EGB06656.1 - 2.2e-152 508.7 0.0 2.5e-152 508.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) CbiA PF01656.23 EGB06656.1 - 0.099 12.7 1.1 0.18 11.8 0.4 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC1 PF03109.16 EGB06658.1 - 3.3e-22 78.9 0.1 6.4e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 ABC1 family Caprin-1_dimer PF18293.1 EGB06658.1 - 0.051 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Caprin-1 dimerization domain WaaY PF06176.11 EGB06658.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1126 PF06565.12 EGB06659.1 - 3.8e-49 164.9 0.0 5.9e-16 58.2 0.0 3.5 3 1 0 3 3 3 3 DUF1126 PH-like domain YchF-GTPase_C PF06071.13 EGB06660.1 - 3.5e-36 123.2 0.0 8.2e-36 122.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGB06660.1 - 9.5e-25 86.9 0.1 3.1e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB06660.1 - 3.1e-08 33.3 0.5 1.1e-07 31.5 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EGB06660.1 - 0.026 13.5 0.2 0.063 12.3 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EGB06660.1 - 0.054 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 EGB06660.1 - 0.097 12.2 0.9 1.9 8.1 0.3 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGB06660.1 - 0.1 12.5 0.1 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Mpv17_PMP22 PF04117.12 EGB06661.1 - 5.5e-18 64.9 1.2 1.3e-17 63.7 1.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family RBP_receptor PF14752.6 EGB06662.1 - 8.2e-10 37.9 10.9 2.8e-05 22.9 1.9 2.9 2 1 1 3 3 3 2 Retinol binding protein receptor LapA_dom PF06305.11 EGB06662.1 - 0.013 15.3 2.3 3.5 7.5 0.2 3.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain CYSTM PF12734.7 EGB06662.1 - 0.059 13.7 0.8 0.15 12.4 0.8 1.7 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF155 PF02582.14 EGB06663.1 - 1e-27 97.4 0.0 1.6e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 EMP24_GP25L PF01105.24 EGB06663.1 - 0.16 11.9 0.6 0.16 11.9 0.6 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Endomucin PF07010.12 EGB06663.1 - 0.73 9.8 1.9 1.1 9.1 1.9 1.2 1 0 0 1 1 1 0 Endomucin Myb_DNA-binding PF00249.31 EGB06664.1 - 8.1e-11 41.9 0.6 0.00035 20.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB06664.1 - 1.3e-10 41.4 0.0 4.1e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Usp PF00582.26 EGB06666.1 - 9.8e-09 35.9 6.7 6.3e-07 30.0 0.1 3.4 3 1 0 3 3 3 2 Universal stress protein family Aconitase_B_N PF11791.8 EGB06666.1 - 0.088 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Aconitate B N-terminal domain Pkinase PF00069.25 EGB06667.1 - 1.6e-52 178.5 0.0 1.9e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06667.1 - 4.4e-24 85.2 0.0 5.4e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB06667.1 - 4.5e-05 22.9 0.0 0.0082 15.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGB06667.1 - 0.00014 21.9 1.3 0.29 11.0 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family bZIP_1 PF00170.21 EGB06668.1 - 0.00033 20.7 17.5 0.0009 19.3 17.5 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGB06668.1 - 0.0012 18.8 19.8 0.016 15.2 19.8 2.2 1 1 0 1 1 1 1 Basic region leucine zipper ZapB PF06005.12 EGB06668.1 - 0.22 12.0 7.0 0.25 11.8 6.0 1.5 1 1 0 1 1 1 0 Cell division protein ZapB PI3K_P85_iSH2 PF16454.5 EGB06668.1 - 0.22 11.1 6.6 0.31 10.6 6.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain bZIP_Maf PF03131.17 EGB06668.1 - 0.44 11.1 16.0 0.75 10.4 16.0 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 EGB06668.1 - 1.2 8.9 4.7 2.2 8.1 4.7 1.4 1 0 0 1 1 1 0 Septum formation initiator HAP1_N PF04849.13 EGB06668.1 - 1.3 8.2 10.9 3.7 6.7 8.9 1.9 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Casc1_N PF15927.5 EGB06668.1 - 2.4 7.8 11.7 3.5 7.3 11.7 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus TMCO5 PF14992.6 EGB06668.1 - 2.7 7.5 7.4 3.5 7.1 7.4 1.1 1 0 0 1 1 1 0 TMCO5 family IATP PF04568.12 EGB06668.1 - 3 8.3 8.2 0.55 10.7 3.8 2.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF3552 PF12072.8 EGB06668.1 - 5.4 6.4 14.8 7.8 5.9 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2462 PF09495.10 EGB06669.1 - 1.2e-05 25.9 13.5 1.2e-05 25.9 13.5 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Nexin_C PF08628.12 EGB06669.1 - 0.033 14.7 1.1 0.051 14.2 1.1 1.3 1 0 0 1 1 1 0 Sorting nexin C terminal Glyco_hydro_32N PF00251.20 EGB06670.1 - 2.6e-28 99.5 0.0 1.4e-26 93.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EGB06670.1 - 3.3e-08 33.7 0.0 5.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DOMON PF03351.17 EGB06672.1 - 3.2e-09 37.0 1.1 5.7e-09 36.3 1.1 1.4 1 0 0 1 1 1 1 DOMON domain MBD PF01429.19 EGB06672.1 - 2.4e-08 33.6 0.1 4.8e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain Bromodomain PF00439.25 EGB06672.1 - 3.7e-06 26.9 0.0 1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Bromodomain HMG_box PF00505.19 EGB06672.1 - 0.0018 18.7 1.0 0.021 15.3 0.4 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB06672.1 - 0.0038 17.8 3.8 0.0039 17.8 0.8 2.6 3 0 0 3 3 3 1 HMG-box domain ThiF PF00899.21 EGB06673.1 - 4.1e-91 304.7 0.0 4.7e-67 225.9 0.0 2.1 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGB06673.1 - 2.2e-79 266.9 0.1 2.9e-79 266.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EGB06673.1 - 3e-26 91.9 0.0 5.6e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EGB06673.1 - 2e-16 60.0 0.0 3.3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EGB06673.1 - 1.8e-11 44.0 0.0 4.6e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle RRM_1 PF00076.22 EGB06674.1 - 3.2e-43 145.4 0.0 3.4e-15 55.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGB06674.1 - 0.0019 18.2 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 EGB06674.1 - 0.037 14.1 0.0 66 3.7 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif OB_RNB PF08206.11 EGB06674.1 - 0.18 11.5 0.6 4.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain PPR PF01535.20 EGB06675.1 - 1.6e-11 43.7 0.1 0.18 12.2 0.0 6.8 7 0 0 7 7 7 4 PPR repeat PPR_1 PF12854.7 EGB06675.1 - 1.3e-07 31.2 0.0 0.11 12.3 0.0 5.4 5 1 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 EGB06675.1 - 5.3e-07 29.6 0.0 0.014 15.5 0.0 4.4 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGB06675.1 - 9e-06 25.8 0.0 0.25 11.6 0.0 4.6 4 0 0 4 4 4 1 PPR repeat family PPR_long PF17177.4 EGB06675.1 - 0.0025 17.2 0.4 0.024 14.0 0.3 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP EF-hand_1 PF00036.32 EGB06675.1 - 0.033 13.7 0.1 0.079 12.5 0.1 1.7 1 0 0 1 1 1 0 EF hand DUF4632 PF15451.6 EGB06675.1 - 0.32 11.1 5.0 2.2 8.4 5.0 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF1325 PF07039.11 EGB06676.1 - 4.5e-08 33.2 0.0 8.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain EamA PF00892.20 EGB06676.1 - 3.3e-05 24.1 16.3 0.0039 17.3 1.8 2.5 2 0 0 2 2 2 2 EamA-like transporter family DUF89 PF01937.19 EGB06677.1 - 1.3e-73 248.0 0.0 1.6e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Kringle PF00051.18 EGB06678.1 - 1.1e-14 54.5 0.7 2.4e-14 53.4 0.7 1.5 1 0 0 1 1 1 1 Kringle domain GPI-anchored PF10342.9 EGB06678.1 - 0.00016 22.4 0.4 24 5.8 0.0 6.0 8 0 0 8 8 8 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1804 PF08822.11 EGB06678.1 - 0.17 11.9 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) cNMP_binding PF00027.29 EGB06679.1 - 4.6e-16 58.7 0.1 1.4e-15 57.1 0.1 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain 5-FTHF_cyc-lig PF01812.20 EGB06680.1 - 1.4e-37 129.4 0.0 2.1e-37 128.8 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Pyrid_oxidase_2 PF13883.6 EGB06680.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Thioredoxin PF00085.20 EGB06681.1 - 9.1e-18 64.1 0.5 1e-17 64.0 0.5 1.0 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EGB06681.1 - 5.6e-05 23.3 0.1 7.7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_8 PF13905.6 EGB06681.1 - 0.00013 22.2 0.0 0.00017 21.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EGB06681.1 - 0.00016 21.7 0.4 0.00031 20.9 0.4 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EGB06681.1 - 0.00031 20.5 0.4 0.0004 20.1 0.4 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 EGB06681.1 - 0.0012 19.2 0.3 0.006 17.0 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EGB06681.1 - 0.0031 17.3 0.1 0.0033 17.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGB06681.1 - 0.0035 17.3 0.1 0.0038 17.1 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EGB06681.1 - 0.074 12.4 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Guanylate_cyc PF00211.20 EGB06682.1 - 1.3e-23 83.6 0.0 6.9e-14 51.9 0.0 2.5 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 EGB06682.1 - 4.6e-11 43.4 1.7 4.6e-11 43.4 1.7 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB06682.1 - 0.0017 18.6 0.0 0.053 13.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain Fe-S_biosyn PF01521.20 EGB06683.1 - 8.7e-08 32.4 0.0 1.1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Na_H_Exchanger PF00999.21 EGB06684.1 - 1.2e-45 155.9 24.3 1.7e-45 155.5 24.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cnd1 PF12717.7 EGB06685.1 - 6.6e-31 107.5 0.0 8.3e-28 97.5 0.0 4.1 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Transglut_core PF01841.19 EGB06685.1 - 0.0034 17.8 1.6 2.2 8.8 0.2 3.1 2 0 0 2 2 2 2 Transglutaminase-like superfamily Cnd3 PF12719.7 EGB06685.1 - 0.0071 15.6 0.0 0.024 13.8 0.0 1.9 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 EGB06685.1 - 0.012 14.2 0.0 0.72 8.3 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region FAM176 PF14851.6 EGB06685.1 - 0.61 9.8 18.6 3.5 7.3 4.0 3.6 3 0 0 3 3 3 0 FAM176 family PqqD PF05402.12 EGB06685.1 - 1.5 9.2 3.7 9.4 6.6 0.0 3.7 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) Methyltransf_10 PF05971.12 EGB06686.1 - 1.1e-81 274.5 0.0 1.3e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EGB06686.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGB06686.1 - 0.045 14.5 0.1 0.52 11.1 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_24 PF13578.6 EGB06686.1 - 0.054 14.5 0.0 0.12 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGB06686.1 - 0.14 12.9 0.0 0.46 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Sulfotransfer_1 PF00685.27 EGB06687.1 - 3.8e-21 75.8 0.0 9.8e-20 71.1 0.0 2.6 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB06687.1 - 2.9e-06 27.9 0.1 0.0043 17.4 0.0 3.2 3 1 1 4 4 4 2 Sulfotransferase family Ephrin_rec_like PF07699.13 EGB06687.1 - 0.009 15.8 18.0 0.033 13.9 3.1 3.7 2 1 1 3 3 3 3 Putative ephrin-receptor like dCache_1 PF02743.18 EGB06687.1 - 0.02 14.7 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Cache domain TRP PF06011.12 EGB06687.1 - 0.13 11.0 0.8 0.22 10.2 0.8 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel NCD3G PF07562.14 EGB06687.1 - 8.7 6.4 11.1 2.8 8.0 0.6 3.0 2 1 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR RRM_1 PF00076.22 EGB06688.1 - 1.8e-06 27.7 0.0 4.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IGPS PF00218.21 EGB06689.1 - 2.6e-23 82.5 0.0 4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase LRR_9 PF14580.6 EGB06689.1 - 2.1e-07 30.6 0.0 3.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EGB06689.1 - 0.0013 18.5 0.1 0.09 12.6 0.1 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EGB06689.1 - 0.0024 18.2 0.4 0.13 12.7 0.3 3.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Rubredoxin_2 PF18073.1 EGB06689.1 - 2.1 8.2 8.9 0.11 12.2 2.8 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain MSC PF09402.10 EGB06689.1 - 8 5.8 5.0 17 4.7 5.0 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain UQ_con PF00179.26 EGB06690.1 - 3.4e-51 172.6 0.0 3.9e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGB06690.1 - 0.0013 18.4 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGB06690.1 - 0.0053 17.0 0.1 0.0081 16.4 0.1 1.5 1 1 0 1 1 1 1 RWD domain AftA_C PF12249.8 EGB06690.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.4 2 0 0 2 2 2 0 Arabinofuranosyltransferase A C terminal Uso1_p115_C PF04871.13 EGB06690.1 - 5.5 7.4 8.7 8.1 6.8 8.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PBP1_TM PF14812.6 EGB06690.1 - 8 6.9 12.1 13 6.2 12.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAD_binding_2 PF00890.24 EGB06691.1 - 4.9e-124 414.6 5.9 6.4e-124 414.2 5.9 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGB06691.1 - 4.5e-43 146.3 0.4 6.6e-43 145.8 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EGB06691.1 - 2.2e-05 23.9 1.7 9.1e-05 21.8 0.2 2.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB06691.1 - 5e-05 22.5 3.2 0.003 16.7 3.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EGB06691.1 - 9e-05 21.8 0.5 0.13 11.5 0.2 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EGB06691.1 - 0.0059 15.9 1.2 0.0077 15.5 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGB06691.1 - 0.012 15.2 0.3 0.027 14.1 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGB06691.1 - 0.051 12.9 4.2 0.13 11.6 4.2 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGB06691.1 - 0.11 11.2 2.5 0.14 10.8 1.3 1.8 2 0 0 2 2 2 0 HI0933-like protein Actin PF00022.19 EGB06692.1 - 7.9e-51 172.9 0.0 4.6e-29 101.3 0.0 2.1 2 0 0 2 2 2 2 Actin ThiF PF00899.21 EGB06693.1 - 1.5e-62 211.2 0.0 1.2e-48 165.7 0.0 3.4 3 1 0 3 3 3 2 ThiF family UBA_e1_thiolCys PF10585.9 EGB06693.1 - 1.1e-56 192.6 0.0 1.8e-56 191.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 EGB06693.1 - 5.9e-15 55.2 0.0 1.4e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 EGB06693.1 - 0.00013 22.1 0.0 0.00065 19.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain Tho1_MOS11_C PF18592.1 EGB06693.1 - 0.15 11.9 0.9 0.3 10.9 0.9 1.4 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain WD40 PF00400.32 EGB06694.1 - 8.9e-24 83.3 29.2 0.054 14.4 0.0 17.6 19 0 0 19 19 19 5 WD domain, G-beta repeat HELP PF03451.14 EGB06694.1 - 5.1e-22 77.5 0.3 1.1e-10 41.2 0.1 3.4 3 0 0 3 3 3 2 HELP motif ANAPC4_WD40 PF12894.7 EGB06694.1 - 1.5e-12 47.6 0.0 0.11 12.8 0.0 8.1 8 3 2 10 10 10 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_6 PF13405.6 EGB06694.1 - 6.5e-05 22.5 1.1 0.12 12.3 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB06694.1 - 0.0025 17.3 2.9 0.2 11.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB06694.1 - 0.011 16.2 1.3 1.6 9.3 0.3 2.6 1 1 0 2 2 2 0 EF-hand domain pair TruB_C PF09142.11 EGB06694.1 - 2.8 7.8 5.4 19 5.1 0.0 4.1 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal WD40 PF00400.32 EGB06695.1 - 0.0012 19.7 1.1 2 9.4 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Oxysterol_BP PF01237.18 EGB06695.1 - 0.19 10.5 0.9 0.29 9.9 0.9 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Tyrosinase PF00264.20 EGB06696.1 - 1.6e-08 35.1 4.4 1.6e-08 35.1 4.4 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase EGF_2 PF07974.13 EGB06697.1 - 1.9e-12 47.3 61.1 2.7e-05 24.4 8.6 5.8 5 1 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 EGB06697.1 - 0.0068 16.5 6.1 0.0068 16.5 6.1 4.7 4 1 0 4 4 4 2 Laminin EGF domain EGF PF00008.27 EGB06697.1 - 1.9 8.8 50.8 2.8 8.3 6.7 6.0 6 0 0 6 6 6 0 EGF-like domain U-box PF04564.15 EGB06698.1 - 5.4e-11 42.5 0.0 9.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain DnaJ PF00226.31 EGB06698.1 - 4e-08 33.3 0.2 8.6e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain zf-Nse PF11789.8 EGB06698.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGB06698.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger SAM_1 PF00536.30 EGB06698.1 - 0.19 12.2 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Sugarporin_N PF11471.8 EGB06699.1 - 0.1 12.6 0.5 0.2 11.6 0.5 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Aminotran_5 PF00266.19 EGB06700.1 - 1.3e-18 67.2 0.0 1.8e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V ABC_tran PF00005.27 EGB06701.1 - 5.8e-47 159.6 0.4 2.4e-22 79.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGB06701.1 - 6.3e-25 87.0 2.8 2.3e-24 85.2 1.9 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EGB06701.1 - 6.4e-10 39.3 10.5 0.032 14.0 0.2 4.6 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB06701.1 - 2e-08 33.9 3.1 0.0016 17.9 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EGB06701.1 - 7.3e-06 26.3 0.3 0.04 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGB06701.1 - 8.1e-06 25.5 0.2 0.0037 17.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB06701.1 - 1.2e-05 25.7 6.7 0.017 15.5 0.0 3.0 3 1 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 EGB06701.1 - 6.8e-05 22.7 3.3 0.066 12.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGB06701.1 - 0.00058 19.8 0.4 0.031 14.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 EGB06701.1 - 0.0008 19.4 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 EGB06701.1 - 0.0012 18.1 0.2 1.6 7.9 0.1 2.7 2 0 0 2 2 2 2 Zeta toxin RuvB_N PF05496.12 EGB06701.1 - 0.0014 18.4 1.1 17 5.1 0.0 4.3 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGB06701.1 - 0.0019 18.8 0.2 0.58 10.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EGB06701.1 - 0.002 18.4 2.5 1.2 9.4 0.1 3.7 3 1 0 3 3 3 1 AAA domain SRP54 PF00448.22 EGB06701.1 - 0.0026 17.4 0.3 0.17 11.5 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EGB06701.1 - 0.0027 17.8 0.2 0.093 12.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EGB06701.1 - 0.0058 17.1 13.5 0.13 12.7 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 EGB06701.1 - 0.0059 16.8 0.4 5.3 7.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF3584 PF12128.8 EGB06701.1 - 0.0078 13.8 0.0 0.0078 13.8 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3584) AAA PF00004.29 EGB06701.1 - 0.0084 16.5 0.5 5.6 7.4 0.0 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 EGB06701.1 - 0.0091 15.7 0.1 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 Thymidylate kinase MeaB PF03308.16 EGB06701.1 - 0.011 14.7 2.3 2.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EGB06701.1 - 0.018 15.2 3.5 0.14 12.3 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain DUF853 PF05872.12 EGB06701.1 - 0.034 12.8 0.1 0.034 12.8 0.1 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_24 PF13479.6 EGB06701.1 - 0.047 13.4 0.0 10 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EGB06701.1 - 0.064 12.8 0.1 8.2 6.0 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EGB06701.1 - 0.082 12.2 0.4 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 EGB06701.1 - 0.18 12.2 3.3 6.5 7.2 0.1 3.3 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EGB06701.1 - 0.18 12.2 0.0 16 5.9 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_27 PF13514.6 EGB06701.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.7 4 0 0 4 4 2 0 AAA domain AAA_13 PF13166.6 EGB06701.1 - 0.32 9.6 0.0 0.32 9.6 0.0 3.2 5 0 0 5 5 4 0 AAA domain AAA_15 PF13175.6 EGB06701.1 - 2.1 8.0 5.2 16 5.0 0.0 3.5 3 1 1 4 4 4 0 AAA ATPase domain AAA_25 PF13481.6 EGB06701.1 - 3.1 7.3 7.7 5 6.7 0.3 3.4 3 1 0 3 3 2 0 AAA domain Globin PF00042.22 EGB06702.1 - 1.3e-11 45.0 0.0 1.7e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Globin Ribonuc_L-PSP PF01042.21 EGB06703.1 - 3e-30 104.7 0.0 3.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP H_PPase PF03030.16 EGB06704.1 - 1.2e-222 741.2 36.8 1.8e-222 740.6 36.8 1.2 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase LSR PF05624.14 EGB06704.1 - 6.4 6.9 6.3 29 4.7 6.3 2.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Hydrolase_4 PF12146.8 EGB06705.1 - 1.4e-07 31.0 0.4 0.0081 15.4 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGB06705.1 - 4.9e-05 22.9 0.0 0.00038 20.0 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGB06705.1 - 6.4e-05 22.7 0.1 0.16 11.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB06705.1 - 8.6e-05 23.2 11.7 0.028 15.0 5.8 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 EGB06705.1 - 0.0023 17.5 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGB06705.1 - 0.1 12.4 0.0 0.77 9.5 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Asp2 PF16929.5 EGB06705.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Pro_isomerase PF00160.21 EGB06706.1 - 8.1e-41 139.9 0.0 1.2e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 EGB06706.1 - 0.014 15.8 0.1 0.019 15.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Mito_carr PF00153.27 EGB06707.1 - 2.1e-31 107.7 2.0 9.6e-17 60.7 0.4 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein L_biotic_typeA PF04604.13 EGB06707.1 - 0.09 12.6 1.1 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Type-A lantibiotic Ras PF00071.22 EGB06708.1 - 4.7e-46 156.4 0.6 9.5e-35 119.6 0.2 2.3 1 1 1 2 2 2 2 Ras family Amino_oxidase PF01593.24 EGB06708.1 - 4e-36 125.3 0.0 5.1e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Roc PF08477.13 EGB06708.1 - 1.1e-19 70.8 0.1 3.7e-10 40.1 0.1 2.6 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB06708.1 - 6.7e-07 28.9 0.1 1.3e-05 24.7 0.0 2.2 1 1 1 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGB06708.1 - 1.5e-05 25.0 0.3 0.091 12.7 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB06708.1 - 0.066 13.6 0.0 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGB06708.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB06708.1 - 0.15 12.5 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.29 EGB06709.1 - 2.1e-30 105.8 0.0 5.2e-30 104.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB06709.1 - 1.6e-19 70.3 0.0 3.4e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB06709.1 - 5.6e-05 23.2 0.0 8.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGB06709.1 - 0.19 12.0 0.1 2.3 8.5 0.1 2.6 1 1 0 2 2 2 0 AAA domain Acyl_transf_3 PF01757.22 EGB06710.1 - 2.7e-17 62.8 8.0 7.5e-17 61.4 8.0 1.7 1 1 0 1 1 1 1 Acyltransferase family KH_1 PF00013.29 EGB06711.1 - 1.3e-18 66.5 2.3 6e-10 38.8 0.1 2.1 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 EGB06711.1 - 9.8e-08 31.8 0.9 3e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EGB06711.1 - 1.7e-07 31.0 0.4 0.0013 18.5 0.2 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 EGB06711.1 - 0.11 12.5 0.8 0.57 10.3 0.3 2.0 2 0 0 2 2 2 0 NusA-like KH domain DEAD PF00270.29 EGB06714.1 - 1.3e-40 139.0 0.0 2.3e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB06714.1 - 6.1e-31 107.0 0.0 7.8e-28 97.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGB06714.1 - 0.00043 20.3 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGB06714.1 - 0.004 16.9 2.9 0.026 14.2 0.1 3.1 3 2 0 3 3 3 1 AAA domain PALP PF00291.25 EGB06715.1 - 3.2e-64 217.2 9.6 3.6e-64 217.0 9.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF389 PF04087.14 EGB06715.1 - 0.42 10.6 3.0 0.69 9.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Glyco_hydro_3 PF00933.21 EGB06716.1 - 6.8e-15 55.3 0.0 4.7e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Sulfatase PF00884.23 EGB06717.1 - 2.6e-24 86.2 0.0 7.4e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 EGB06717.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Phosphodiest PF01663.22 EGB06717.1 - 0.039 13.5 0.0 0.084 12.4 0.0 1.4 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase ETF PF01012.21 EGB06720.1 - 4.9e-47 160.2 2.7 6.4e-47 159.8 2.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain BID PF06393.11 EGB06720.1 - 0.084 12.4 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) Hist_deacetyl PF00850.19 EGB06721.1 - 1.9e-40 139.2 0.0 4.2e-40 138.1 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain Glyco_hydro_3_C PF01915.22 EGB06721.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain TraE PF05309.11 EGB06721.1 - 0.15 11.4 0.0 0.86 9.0 0.0 2.0 2 0 0 2 2 2 0 TraE protein RNA_pol_Rpb1_5 PF04998.17 EGB06722.1 - 1.5e-62 211.5 0.0 5.7e-54 183.3 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGB06722.1 - 5.8e-54 182.8 0.0 1e-53 182.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGB06722.1 - 2.7e-27 95.6 0.0 4.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGB06722.1 - 3.1e-19 68.9 0.0 5.9e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 EGB06722.1 - 0.0014 18.0 0.0 0.0096 15.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 DUF2457 PF10446.9 EGB06722.1 - 2.1 7.4 10.3 4.3 6.4 10.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 EGB06722.1 - 3.1 5.9 8.2 5.4 5.1 8.2 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGB06722.1 - 6 6.1 15.6 0.34 10.2 10.3 1.5 2 0 0 2 2 2 0 BUD22 Thioredoxin PF00085.20 EGB06723.1 - 1.9e-07 31.0 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DnaJ PF00226.31 EGB06723.1 - 7.3e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_8 PF13905.6 EGB06723.1 - 0.021 15.2 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB06723.1 - 0.024 15.1 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.10 EGB06723.1 - 0.037 13.7 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 EGB06723.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DUF563 PF04577.14 EGB06724.1 - 8.5e-15 55.4 0.0 1.4e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TetR_C_20 PF17925.1 EGB06724.1 - 0.42 10.9 5.2 0.49 10.7 2.1 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain fn3 PF00041.21 EGB06725.1 - 1e-12 48.2 0.2 0.059 13.7 0.0 5.6 6 1 0 6 6 6 3 Fibronectin type III domain Ank_2 PF12796.7 EGB06725.1 - 2.4e-12 47.3 0.1 1.5e-06 28.7 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB06725.1 - 1.1e-08 35.4 0.0 4.1e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB06725.1 - 3.9e-07 30.2 0.1 0.013 15.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB06725.1 - 1.2e-05 25.3 0.0 0.023 15.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EGB06725.1 - 0.00014 22.1 0.1 0.99 10.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Tup_N PF08581.10 EGB06726.1 - 0.0044 17.3 7.9 1.8 8.9 0.2 3.5 1 1 1 3 3 3 2 Tup N-terminal THOC7 PF05615.13 EGB06726.1 - 0.023 15.0 18.9 0.14 12.5 8.4 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4800 PF16057.5 EGB06726.1 - 0.091 12.0 17.7 1.6 8.0 4.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4800) Spc7 PF08317.11 EGB06726.1 - 0.19 10.6 16.5 4.5 6.1 16.9 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 EGB06726.1 - 0.83 7.1 26.5 1.9 5.9 26.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CortBP2 PF09727.9 EGB06726.1 - 1 9.3 15.1 3.7 7.4 14.1 2.2 1 1 2 3 3 3 0 Cortactin-binding protein-2 CASP_C PF08172.12 EGB06726.1 - 3.7 6.8 10.4 4 6.7 2.4 2.5 1 1 1 2 2 2 0 CASP C terminal ADIP PF11559.8 EGB06726.1 - 8.4 6.5 18.9 13 5.8 8.1 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DSBA PF01323.20 EGB06727.1 - 1.4e-05 24.9 0.2 8e-05 22.5 0.0 2.0 1 1 0 2 2 2 1 DSBA-like thioredoxin domain Med3 PF11593.8 EGB06727.1 - 1 8.5 3.3 1.4 8.0 3.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PSII_Pbs27 PF13326.6 EGB06728.1 - 5.3e-27 94.9 0.3 5.9e-27 94.7 0.3 1.0 1 0 0 1 1 1 1 Photosystem II Pbs27 Pyr_redox_2 PF07992.14 EGB06729.1 - 1.8e-42 145.6 1.6 2.4e-42 145.2 1.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB06729.1 - 3e-06 27.7 8.0 3.6e-05 24.2 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Hydrolase_like PF13242.6 EGB06729.1 - 0.045 13.8 0.0 0.59 10.2 0.0 2.4 2 0 0 2 2 2 0 HAD-hyrolase-like tRNA_bind PF01588.20 EGB06730.1 - 6.6e-29 99.9 0.0 8.8e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain WD40 PF00400.32 EGB06731.1 - 1.3e-38 130.2 19.5 1.7e-07 31.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06731.1 - 3.4e-19 68.9 1.0 8.1e-05 22.8 0.0 5.9 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB06731.1 - 3.7e-12 45.9 1.4 0.16 10.9 0.0 5.3 2 1 3 5 5 5 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB06731.1 - 1.8e-09 37.7 1.2 4.4e-05 23.4 0.0 4.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EGB06731.1 - 4.1e-06 25.4 0.0 0.037 12.4 0.0 2.9 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EGB06731.1 - 5.4e-06 26.0 0.5 0.037 13.4 0.0 4.0 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 EGB06731.1 - 3.6e-05 22.5 0.6 0.61 8.6 0.0 3.2 2 1 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 EGB06731.1 - 0.005 15.6 2.4 0.13 10.9 0.1 3.0 1 1 2 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 EGB06731.1 - 0.0051 16.7 3.0 1.3 9.1 0.0 4.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 EGB06731.1 - 0.011 14.7 0.1 0.011 14.7 0.1 2.8 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain IKI3 PF04762.12 EGB06731.1 - 0.024 12.7 0.1 0.16 10.0 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Coatomer_WDAD PF04053.14 EGB06731.1 - 0.028 13.5 0.0 0.074 12.1 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region DUF1513 PF07433.11 EGB06731.1 - 0.083 12.0 3.4 4 6.4 1.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) Sulfotransfer_2 PF03567.14 EGB06732.1 - 9.6e-08 32.2 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Glyco_hydro_20 PF00728.22 EGB06733.1 - 3.3e-72 243.8 0.0 1.4e-70 238.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGB06733.1 - 2.5e-14 54.1 0.0 7.8e-13 49.3 0.0 2.2 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGB06733.1 - 7.1e-06 26.8 0.0 1.8e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Castor_Poll_mid PF06241.12 EGB06734.1 - 1.4e-23 82.8 0.0 1.2e-21 76.6 0.0 2.4 2 0 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel APG6_N PF17675.1 EGB06735.1 - 0.0024 18.4 7.2 0.0059 17.1 7.2 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region ZapB PF06005.12 EGB06735.1 - 0.05 14.1 8.4 0.044 14.2 4.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 EGB06735.1 - 0.099 12.7 6.5 0.19 11.8 6.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 EGB06735.1 - 0.13 11.5 3.7 0.33 10.2 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC24 PF15669.5 EGB06735.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.8 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 24 family GIT_CC PF16559.5 EGB06735.1 - 0.39 10.6 1.7 0.64 9.9 0.5 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor NYD-SP28_assoc PF14775.6 EGB06735.1 - 1.4 9.1 5.6 1.5 9.0 1.7 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain Cnn_1N PF07989.11 EGB06735.1 - 1.5 9.0 4.1 3.8 7.7 4.1 1.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Med21 PF11221.8 EGB06735.1 - 3.5 7.9 6.4 3.9 7.7 3.8 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Kinesin PF00225.23 EGB06737.1 - 1.4e-59 201.7 0.0 1.6e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB06737.1 - 1.9e-22 79.8 0.0 3e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding TTL PF03133.15 EGB06740.1 - 1.8e-13 50.3 0.0 4.3e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB06740.1 - 1.2e-07 31.3 0.0 2.1e-05 23.9 0.0 2.4 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGB06740.1 - 0.0039 16.5 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EGB06740.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain TPR_19 PF14559.6 EGB06740.1 - 0.016 15.7 6.3 0.4 11.2 5.6 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06740.1 - 0.24 11.6 6.5 7.7 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06740.1 - 1.9 8.8 9.8 3.5 8.0 4.9 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4239 PF14023.6 EGB06741.1 - 5.1e-11 42.7 0.1 1.1e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4239) Cyclin_N PF00134.23 EGB06742.1 - 1.3e-13 50.8 0.0 2.4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC1 PF03109.16 EGB06743.1 - 2.5e-16 59.9 0.0 3e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 EGB06743.1 - 0.022 14.1 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 EGB06743.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGB06743.1 - 0.36 10.7 17.0 0.013 15.4 3.4 3.6 3 1 0 3 3 3 0 Phosphotransferase enzyme family zf-RING_5 PF14634.6 EGB06744.1 - 9.2e-05 22.3 7.1 9.2e-05 22.3 7.1 5.4 8 0 0 8 8 8 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGB06744.1 - 0.006 16.9 7.5 0.006 16.9 7.5 5.9 6 1 0 6 6 6 1 Ring finger domain Prefoldin PF02996.17 EGB06745.1 - 3.2e-25 88.4 2.7 4.8e-25 87.8 2.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 EGB06745.1 - 0.67 9.8 10.6 0.15 11.9 2.2 2.4 2 1 0 2 2 2 0 Septum formation initiator Csm1_N PF18504.1 EGB06745.1 - 0.71 10.2 12.3 1.8 9.0 2.7 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Atg14 PF10186.9 EGB06745.1 - 0.87 8.6 7.8 1.6 7.7 0.7 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FmdA_AmdA PF03069.15 EGB06746.1 - 2.2e-171 569.8 0.0 2.5e-171 569.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Abhydrolase_3 PF07859.13 EGB06748.1 - 0.00025 21.0 0.0 0.00074 19.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EGB06748.1 - 0.0007 19.8 0.1 0.0011 19.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGB06748.1 - 0.00096 19.8 11.8 0.00096 19.8 11.8 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB06748.1 - 0.0022 17.3 0.2 0.0069 15.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGB06748.1 - 0.0034 17.2 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EGB06748.1 - 0.012 14.6 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1749 PF08538.10 EGB06748.1 - 0.025 13.7 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Esterase PF00756.20 EGB06748.1 - 0.035 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 EGB06748.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 EGB06748.1 - 0.096 12.3 0.1 0.29 10.7 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGB06748.1 - 0.11 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Sel1 PF08238.12 EGB06749.1 - 7e-26 90.1 12.1 1.5e-08 35.0 0.1 4.3 4 1 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB06749.1 - 0.00028 21.4 7.1 0.002 18.8 2.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06749.1 - 0.15 12.3 3.8 1 9.7 0.5 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 EGB06750.1 - 8.3e-15 54.9 9.5 9.6e-15 54.6 9.5 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGB06750.1 - 1.4e-11 43.9 7.6 1.4e-11 43.9 7.6 1.4 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGB06750.1 - 8.8e-10 38.3 8.9 1.1e-09 38.0 8.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB06750.1 - 2.9e-09 37.1 9.5 7.8e-09 35.7 9.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGB06750.1 - 3.4e-09 36.6 1.1 3.4e-09 36.6 1.1 1.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGB06750.1 - 3.4e-08 33.2 6.2 4.1e-08 33.0 6.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB06750.1 - 7.4e-08 32.1 8.9 9.5e-08 31.8 8.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB06750.1 - 1e-06 28.6 7.7 1.3e-06 28.2 7.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGB06750.1 - 0.00018 21.5 7.4 0.00054 20.0 7.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGB06750.1 - 0.00032 20.5 6.5 0.0021 17.9 6.6 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGB06750.1 - 0.0023 18.0 6.4 0.0086 16.2 6.5 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EGB06750.1 - 0.0086 15.7 7.6 0.016 14.8 7.6 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EGB06750.1 - 0.011 15.5 8.0 0.017 14.9 8.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EGB06750.1 - 0.012 15.7 11.4 0.44 10.8 11.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.11 EGB06750.1 - 0.013 15.5 2.0 0.017 15.1 2.0 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.7 EGB06750.1 - 0.017 15.2 7.0 0.029 14.5 7.0 1.4 1 1 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 EGB06750.1 - 0.068 13.1 7.1 1.5 8.8 4.1 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Rtf2 PF04641.12 EGB06750.1 - 0.11 11.9 0.9 0.13 11.7 0.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CxC4 PF18717.1 EGB06750.1 - 0.14 12.0 2.2 0.16 11.9 2.2 1.0 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases PHD PF00628.29 EGB06750.1 - 0.44 10.5 8.8 1.5 8.7 8.9 1.8 1 1 0 1 1 1 0 PHD-finger Abhydrolase_2 PF02230.16 EGB06751.1 - 3.1e-08 33.7 0.0 4.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase ADH_N PF08240.12 EGB06751.1 - 9.4e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGB06751.1 - 5e-05 23.3 0.0 9.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Esterase PF00756.20 EGB06751.1 - 0.0063 16.2 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 EGB06751.1 - 0.042 13.4 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family RCC1 PF00415.18 EGB06752.1 - 3e-33 114.2 15.8 9.7e-11 42.1 0.5 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB06752.1 - 1.1e-11 44.2 19.8 0.0074 16.1 0.2 5.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Tyrosinase PF00264.20 EGB06752.1 - 1.3e-09 38.7 0.1 3.6e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Common central domain of tyrosinase DAGAT PF03982.13 EGB06753.1 - 8.9e-70 234.9 0.0 9.7e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase FKBP_C PF00254.28 EGB06754.1 - 0.003 17.9 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyclase_polyket PF04673.12 EGB06754.1 - 0.033 14.4 0.1 0.087 13.1 0.1 1.7 1 0 0 1 1 1 0 Polyketide synthesis cyclase PK PF00224.21 EGB06755.1 - 2.6e-105 352.1 0.0 3.5e-105 351.7 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGB06755.1 - 7.5e-27 93.9 0.0 1.8e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 EGB06755.1 - 0.012 14.6 0.0 0.14 11.1 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Asp-Al_Ex PF06826.12 EGB06756.1 - 0.027 14.3 1.6 1.2 8.9 0.1 2.3 1 1 1 2 2 2 0 Predicted Permease Membrane Region DUF4293 PF14126.6 EGB06756.1 - 0.089 13.0 0.0 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) LRR_9 PF14580.6 EGB06758.1 - 9.2e-18 64.3 0.3 1.1e-17 64.1 0.3 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGB06758.1 - 1.9e-13 50.4 1.2 0.0002 21.6 0.0 3.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB06758.1 - 8.1e-09 35.1 4.4 0.0002 21.0 1.9 2.5 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EGB06758.1 - 0.00035 20.7 4.1 1.7 9.5 0.0 3.8 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 EGB06758.1 - 1.7 8.9 4.3 46 4.4 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Methyltransf_21 PF05050.12 EGB06759.1 - 3.5e-10 40.2 0.0 6.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain COesterase PF00135.28 EGB06760.1 - 8.2e-67 226.2 0.0 9e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGB06760.1 - 4.3e-05 23.5 0.0 0.0003 20.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB06760.1 - 0.002 17.6 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2754 PF10953.8 EGB06761.1 - 0.016 15.4 2.6 36 4.7 1.3 4.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2754) Chorion_1 PF01723.16 EGB06761.1 - 0.031 14.2 0.7 0.43 10.5 0.3 2.2 1 1 1 2 2 2 0 Chorion protein Lamprin PF06403.11 EGB06761.1 - 0.24 11.4 4.2 2.6 8.0 4.2 2.5 1 1 0 1 1 1 0 Lamprin cNMP_binding PF00027.29 EGB06762.1 - 0.00031 20.8 0.0 0.00074 19.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TAT_ubiq PF07706.12 EGB06762.1 - 0.16 12.2 0.1 30 4.9 0.0 2.6 2 0 0 2 2 2 0 Aminotransferase ubiquitination site ArfGap PF01412.18 EGB06763.1 - 3.9e-32 110.8 0.3 4.6e-32 110.6 0.3 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 EGB06763.1 - 0.036 14.0 2.1 0.22 11.5 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn_Tnp_IS1595 PF12760.7 EGB06763.1 - 0.046 13.7 0.3 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Vint PF14623.6 EGB06764.1 - 1.5e-22 80.2 0.0 2.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Methyltransf_23 PF13489.6 EGB06764.1 - 1.5e-16 60.6 0.0 2.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Vwaint PF14624.6 EGB06764.1 - 2.6e-14 53.1 0.0 5.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 EGB06764.1 - 3.5e-11 43.6 0.0 6.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Methyltransf_11 PF08241.12 EGB06764.1 - 1.9e-09 38.0 1.1 3.6e-08 33.9 0.1 3.1 3 0 0 3 3 3 1 Methyltransferase domain VWA_2 PF13519.6 EGB06764.1 - 3.8e-09 37.1 0.1 1.4e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Methyltransf_25 PF13649.6 EGB06764.1 - 9.1e-09 35.9 0.1 4.7e-08 33.6 0.1 2.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB06764.1 - 8.2e-07 28.6 0.0 2.5e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGB06764.1 - 1.2e-06 29.1 0.0 3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain VWA_3 PF13768.6 EGB06764.1 - 5.9e-06 26.3 0.3 5.1e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain Methyltransf_31 PF13847.6 EGB06764.1 - 7.1e-05 22.6 0.0 0.00047 20.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Lipase_GDSL_2 PF13472.6 EGB06765.1 - 0.064 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family LRR_1 PF00560.33 EGB06766.1 - 1.3e-06 28.1 0.0 4.2 8.3 0.0 6.7 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 EGB06766.1 - 4.2e-06 26.4 19.1 0.25 11.5 0.0 8.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_8 PF13855.6 EGB06766.1 - 0.0001 22.0 2.2 4.6 7.1 0.9 5.6 6 1 0 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 EGB06766.1 - 0.00012 22.4 0.1 0.56 10.7 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 EGB06767.1 - 0.00011 22.0 0.1 0.00097 19.1 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06767.1 - 0.00017 21.2 0.0 0.0009 19.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB06767.1 - 0.00098 19.6 0.0 0.26 11.8 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06767.1 - 0.0047 17.6 0.2 0.16 12.9 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06767.1 - 0.014 15.7 0.1 0.048 13.9 0.0 1.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB06767.1 - 0.021 14.7 0.1 0.058 13.3 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06767.1 - 0.032 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB06767.1 - 0.05 13.8 0.2 0.43 10.8 0.3 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06767.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB06767.1 - 0.085 13.3 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 EGB06768.1 - 1e-15 57.2 29.0 8.5e-08 31.9 7.6 4.8 6 0 0 6 6 6 2 RING/Ubox like zinc-binding domain cNMP_binding PF00027.29 EGB06768.1 - 9.2e-15 54.5 0.0 5.3e-13 48.9 0.0 3.0 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain zf-RING_2 PF13639.6 EGB06768.1 - 5.9e-11 42.5 22.3 4.1e-05 23.8 7.2 2.8 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 EGB06768.1 - 0.00011 22.0 21.0 0.046 13.6 6.5 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 EGB06768.1 - 0.0028 17.4 7.4 0.74 9.7 0.9 3.2 2 0 0 2 2 2 2 Zinc finger, ZZ type zf-RING_UBOX PF13445.6 EGB06768.1 - 0.0065 16.5 12.2 0.42 10.7 2.4 2.6 2 0 0 2 2 2 2 RING-type zinc-finger Vps39_2 PF10367.9 EGB06768.1 - 0.0078 16.6 1.6 6.5 7.3 0.1 3.1 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.25 EGB06768.1 - 0.029 14.2 18.8 0.73 9.8 5.4 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cwf_Cwc_15 PF04889.12 EGB06768.1 - 0.095 12.4 24.3 0.0083 15.9 9.4 3.0 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein TackOD1 PF18551.1 EGB06768.1 - 0.18 11.5 6.0 5.9 6.5 0.6 2.8 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 SHNi-TPR PF10516.9 EGB06768.1 - 0.23 10.9 0.8 27 4.3 0.1 2.7 2 0 0 2 2 2 0 SHNi-TPR zf-RING_11 PF17123.5 EGB06768.1 - 0.55 10.0 12.8 3.5 7.4 2.6 2.6 2 0 0 2 2 2 0 RING-like zinc finger PPIP5K2_N PF18086.1 EGB06769.1 - 3.8e-38 129.5 0.0 6.8e-38 128.7 0.0 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain His_Phos_2 PF00328.22 EGB06769.1 - 3.9e-33 115.3 0.1 6.4e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.11 EGB06769.1 - 0.00098 18.8 0.0 0.0023 17.6 0.0 1.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Hemerythrin PF01814.23 EGB06769.1 - 4.9 7.8 5.8 48 4.6 0.1 3.7 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain Glutaredoxin PF00462.24 EGB06770.1 - 0.036 14.3 0.6 0.77 10.0 0.0 2.6 2 1 1 3 3 3 0 Glutaredoxin adh_short_C2 PF13561.6 EGB06771.1 - 5.9e-52 176.5 3.2 7.5e-52 176.2 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB06771.1 - 4.4e-50 169.9 0.1 5.8e-50 169.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB06771.1 - 1.4e-11 44.7 0.6 2e-11 44.1 0.6 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGB06771.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 EGB06771.1 - 0.022 14.6 1.0 0.032 14.1 1.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EGB06771.1 - 0.032 13.7 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-DNL PF05180.12 EGB06772.1 - 8.7e-14 51.2 0.3 9e-14 51.2 0.3 1.0 1 0 0 1 1 1 1 DNL zinc finger Pkinase PF00069.25 EGB06773.1 - 1.8e-47 161.9 0.0 2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06773.1 - 6.3e-33 114.1 0.0 6.9e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB06773.1 - 2.1e-05 23.5 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB06773.1 - 0.01 15.8 1.0 0.79 9.6 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Alpha-mann_mid PF09261.11 EGB06773.1 - 0.05 13.7 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha mannosidase middle domain Kinase-like PF14531.6 EGB06773.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EGB06773.1 - 0.14 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 dCache_1 PF02743.18 EGB06774.1 - 8.3e-06 25.8 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Cache domain DZR PF12773.7 EGB06775.1 - 1 9.4 4.1 15 5.7 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon ABC_tran PF00005.27 EGB06776.1 - 3.7e-39 134.4 0.0 7.8e-28 97.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGB06776.1 - 3.3e-29 102.4 0.2 4.8e-29 101.9 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGB06776.1 - 0.00013 21.5 0.0 1.6 8.2 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EGB06776.1 - 0.0024 18.0 0.2 0.0043 17.2 0.2 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 EGB06776.1 - 0.0052 17.2 0.4 0.0052 17.2 0.4 2.6 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGB06776.1 - 0.0092 16.1 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGB06776.1 - 0.016 14.9 0.0 0.053 13.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EGB06776.1 - 0.018 14.1 0.3 0.034 13.1 0.3 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EGB06776.1 - 0.026 14.6 0.1 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EGB06776.1 - 0.19 11.5 2.1 0.56 9.9 2.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGB06777.1 - 1.2e-35 122.8 0.0 1.6e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB06777.1 - 6.4e-10 38.7 1.4 7.6e-10 38.4 0.1 1.9 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 EGB06777.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EGB06777.1 - 0.00015 21.6 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGB06777.1 - 0.00035 21.0 0.2 0.036 14.5 0.1 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EGB06777.1 - 0.00056 20.1 0.0 0.00077 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGB06777.1 - 0.001 19.1 0.6 0.019 15.0 0.6 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGB06777.1 - 0.0033 16.8 0.1 0.0063 15.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EGB06777.1 - 0.0068 16.7 0.2 0.036 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB06777.1 - 0.0075 16.4 0.0 0.014 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGB06777.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EGB06777.1 - 0.039 13.1 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 EGB06777.1 - 0.044 14.3 0.1 0.074 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB06777.1 - 0.07 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB06777.1 - 0.078 12.9 0.1 1.3 8.9 0.1 2.3 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 EGB06777.1 - 0.096 12.3 1.0 0.34 10.4 1.0 2.0 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGB06777.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EGB06777.1 - 0.26 10.7 0.1 0.4 10.1 0.1 1.4 1 1 0 1 1 1 0 PhoH-like protein Calreticulin PF00262.18 EGB06778.1 - 3.9e-06 26.0 0.3 6.2e-06 25.3 0.3 1.2 1 0 0 1 1 1 1 Calreticulin family DUF4913 PF16259.5 EGB06778.1 - 0.0066 16.5 1.5 0.1 12.7 1.5 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4913) Actin PF00022.19 EGB06780.1 - 1.9e-144 481.2 0.0 6.2e-144 479.6 0.0 1.6 1 1 0 1 1 1 1 Actin Sulfate_transp PF00916.20 EGB06781.1 - 5.8e-30 104.3 28.1 3.8e-28 98.3 28.1 2.1 1 1 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 EGB06781.1 - 6.8e-07 29.5 0.4 6.8e-07 29.5 0.4 3.3 4 0 0 4 4 4 1 STAS domain STAS PF01740.21 EGB06781.1 - 1.8e-05 24.3 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain zf-MYND PF01753.18 EGB06781.1 - 0.0011 19.0 9.6 0.0011 19.0 9.6 2.5 3 0 0 3 3 3 1 MYND finger Rdx PF10262.9 EGB06782.1 - 5.8e-08 32.8 0.0 7.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family DHFR_2 PF06442.11 EGB06782.1 - 0.099 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 R67 dihydrofolate reductase Peptidase_S24 PF00717.23 EGB06783.1 - 1.9e-09 37.3 0.0 4.8e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGB06783.1 - 5.2e-08 32.8 0.1 1.8e-07 31.0 0.1 1.9 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Beta_helix PF13229.6 EGB06783.1 - 0.00012 21.9 0.0 0.05 13.5 0.0 2.4 2 0 0 2 2 2 2 Right handed beta helix region LRR_8 PF13855.6 EGB06783.1 - 0.00037 20.2 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EGB06783.1 - 0.0014 19.0 0.0 2.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Ephrin_rec_like PF07699.13 EGB06783.1 - 3.2 7.6 5.8 5.8 6.8 0.7 2.5 2 0 0 2 2 2 0 Putative ephrin-receptor like DUF4212 PF13937.6 EGB06783.1 - 9.3 6.7 9.0 0.38 11.2 1.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Exo_endo_phos PF03372.23 EGB06784.1 - 1.1e-07 31.6 0.0 3.3e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EGB06785.1 - 1.5e-27 95.3 26.9 7.9e-05 23.4 0.1 11.9 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06785.1 - 1.4e-08 34.9 0.6 0.19 12.1 0.0 5.0 6 0 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGB06785.1 - 0.081 13.4 4.2 27 5.4 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain FBPase PF00316.20 EGB06786.1 - 5.4e-56 189.1 0.2 7.6e-56 188.6 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain WD40 PF00400.32 EGB06787.1 - 4.5e-15 55.8 17.5 0.0019 19.0 0.4 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06787.1 - 2.1e-11 43.9 0.2 0.0096 16.2 0.1 4.4 3 2 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB06787.1 - 1.4e-06 28.3 1.1 0.02 14.8 0.2 3.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGB06787.1 - 5.1e-06 26.3 0.1 0.11 12.5 0.0 3.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGB06787.1 - 0.0045 16.0 0.9 0.28 10.1 0.4 3.4 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 EGB06787.1 - 0.019 13.7 2.0 7.5 5.2 0.3 3.6 2 1 2 4 4 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 EGB06787.1 - 0.032 14.2 0.1 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3748) IKI3 PF04762.12 EGB06787.1 - 0.06 11.3 1.5 4.4 5.2 0.9 2.5 2 1 0 3 3 3 0 IKI3 family Ribul_P_3_epim PF00834.19 EGB06788.1 - 2.7e-62 209.7 0.0 3.2e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family IMPDH PF00478.25 EGB06788.1 - 0.097 11.7 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain SufE PF02657.15 EGB06789.1 - 1.5e-31 108.8 0.0 1.6e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain Zip PF02535.22 EGB06790.1 - 1e-08 34.8 10.3 1e-08 34.8 10.3 2.5 3 1 0 3 3 3 2 ZIP Zinc transporter DUF543 PF04418.12 EGB06790.1 - 0.75 9.8 9.8 16 5.6 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF543) Zip PF02535.22 EGB06791.1 - 4.2e-16 59.1 15.8 2.3e-15 56.7 6.7 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter PelG PF16933.5 EGB06791.1 - 0.064 12.1 0.2 0.14 11.0 0.2 1.5 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) ABC2_membrane_5 PF13346.6 EGB06791.1 - 0.079 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Pkinase PF00069.25 EGB06792.1 - 1.5e-50 172.0 0.0 2e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06792.1 - 1.3e-25 90.2 0.0 1.8e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB06792.1 - 1.8e-05 24.8 0.1 0.0018 18.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGB06792.1 - 0.0009 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 EGB06792.1 - 0.0069 15.7 0.0 1.5 8.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kri1 PF05178.12 EGB06792.1 - 0.046 14.3 0.1 0.084 13.4 0.1 1.5 1 0 0 1 1 1 0 KRI1-like family Gly-zipper_Omp PF13488.6 EGB06793.1 - 0.02 14.9 13.3 0.02 14.9 13.3 6.8 2 1 4 6 6 6 0 Glycine zipper Aa_trans PF01490.18 EGB06794.1 - 4.7e-47 160.6 8.1 6.5e-47 160.1 8.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PhyH PF05721.13 EGB06794.1 - 2.8e-09 37.5 0.5 7.4e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Trp_Tyr_perm PF03222.13 EGB06794.1 - 0.00063 18.9 4.0 0.0014 17.7 4.0 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family GST_N_2 PF13409.6 EGB06795.1 - 2.5e-16 59.7 0.0 7.6e-16 58.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB06795.1 - 3.6e-06 27.3 0.1 0.0002 21.7 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB06795.1 - 3.5e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB06795.1 - 0.00022 21.2 1.5 0.00022 21.2 1.5 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PAS_9 PF13426.7 EGB06796.1 - 6.7e-23 80.9 0.0 7.7e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EGB06796.1 - 2.8e-08 33.9 0.0 3.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EGB06796.1 - 5e-08 32.9 0.0 7.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGB06796.1 - 9.9e-07 29.0 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EGB06796.1 - 0.021 14.8 0.0 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 PAS domain FA_desaturase PF00487.24 EGB06797.1 - 1.6e-24 87.2 16.0 2e-24 86.9 16.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EGB06797.1 - 3.9e-12 45.5 1.7 7e-12 44.6 1.7 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) PP2C PF00481.21 EGB06798.1 - 3.4e-50 171.1 0.0 4e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB06798.1 - 4.7e-07 29.9 0.1 0.022 14.7 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGB06798.1 - 6e-06 26.0 0.1 1.5e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C DEAD PF00270.29 EGB06799.1 - 5.3e-16 58.9 0.0 9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB06799.1 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGB06799.1 - 7.2e-06 26.3 0.0 1.5e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGB06799.1 - 0.0031 17.3 0.0 0.0083 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGB06799.1 - 0.0099 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 EGB06799.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Myosin_head PF00063.21 EGB06800.1 - 3.6e-22 78.4 0.1 3.8e-22 78.3 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.21 EGB06801.1 - 3.8e-75 253.5 0.0 4.6e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pyrid_oxidase_2 PF13883.6 EGB06802.1 - 1.7e-14 54.1 0.0 1.9e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Thioredoxin_8 PF13905.6 EGB06803.1 - 5.8e-56 186.8 0.0 1.1e-28 99.3 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin PF00085.20 EGB06803.1 - 6.5e-18 64.6 0.0 1.2e-05 25.2 0.0 4.2 3 1 1 4 4 4 3 Thioredoxin AhpC-TSA PF00578.21 EGB06803.1 - 3.3e-15 56.1 0.0 1.3e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 EGB06803.1 - 2.3e-12 46.8 0.0 2.9e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_2 PF13098.6 EGB06803.1 - 3.5e-12 46.7 0.0 2e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGB06803.1 - 2.4e-06 27.6 0.0 0.12 12.6 0.0 3.0 2 2 0 2 2 2 2 Thioredoxin-like NADH_4Fe-4S PF10589.9 EGB06803.1 - 0.019 15.1 0.0 7 6.8 0.0 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region TraF PF13728.6 EGB06803.1 - 0.024 14.5 0.0 0.92 9.3 0.0 3.1 3 1 0 3 3 3 0 F plasmid transfer operon protein HyaE PF07449.11 EGB06803.1 - 0.13 12.2 0.0 31 4.6 0.0 2.9 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Usp PF00582.26 EGB06803.1 - 0.18 12.3 1.4 0.72 10.4 0.5 2.2 2 0 0 2 2 2 0 Universal stress protein family Ribosomal_S3_C PF00189.20 EGB06804.1 - 2e-24 85.9 1.4 1.1e-23 83.6 2.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGB06804.1 - 4.6e-12 45.6 0.1 8e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EGB06804.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Methyltransf_2 PF00891.18 EGB06806.1 - 0.00011 21.5 0.0 0.00022 20.6 0.0 1.4 1 1 1 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGB06806.1 - 0.001 19.8 0.1 0.0019 18.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB06806.1 - 0.0022 17.9 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB06806.1 - 0.0037 17.1 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB06806.1 - 0.023 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain TPR_12 PF13424.6 EGB06807.1 - 2.9e-159 517.7 100.3 3.4e-17 62.5 1.8 11.1 3 2 10 14 14 14 14 Tetratricopeptide repeat TPR_10 PF13374.6 EGB06807.1 - 1e-117 381.3 70.2 2e-11 43.4 0.8 17.6 17 1 0 17 17 17 17 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06807.1 - 1.6e-59 195.4 53.4 0.00015 21.4 0.1 17.1 17 0 0 17 17 17 13 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06807.1 - 1e-53 175.1 65.7 0.0014 18.6 0.5 16.8 17 0 0 17 17 17 13 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06807.1 - 2.3e-44 146.2 51.9 0.00015 21.6 0.3 17.3 17 0 0 17 17 17 10 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06807.1 - 1.7e-37 124.5 44.5 0.0016 18.5 0.3 15.0 16 0 0 16 16 14 9 Tetratricopeptide repeat TPR_16 PF13432.6 EGB06807.1 - 1.4e-24 86.4 64.6 3.9e-06 27.4 4.0 12.7 5 3 7 14 14 14 8 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB06807.1 - 2e-23 83.3 27.4 0.00042 19.8 3.7 6.8 1 1 6 7 7 7 7 MalT-like TPR region TPR_14 PF13428.6 EGB06807.1 - 8.8e-20 69.7 66.5 0.068 14.0 0.4 16.2 5 3 10 16 16 16 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGB06807.1 - 1.2e-19 70.5 47.8 0.057 13.9 0.8 11.7 3 3 12 15 15 15 12 Tetratricopeptide repeat TPR_17 PF13431.6 EGB06807.1 - 1.1e-16 59.9 32.8 0.37 11.3 0.2 16.1 17 0 0 17 17 17 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB06807.1 - 2.5e-13 49.5 33.3 1.7 8.4 0.3 13.4 14 2 2 16 16 16 5 TPR repeat SHNi-TPR PF10516.9 EGB06807.1 - 5.9e-09 35.2 9.7 1 8.9 0.0 9.1 10 0 0 10 10 9 2 SHNi-TPR TPR_5 PF12688.7 EGB06807.1 - 1.4e-08 35.0 24.0 0.071 13.4 0.1 8.6 6 3 1 7 7 7 2 Tetratrico peptide repeat ANAPC3 PF12895.7 EGB06807.1 - 5.2e-08 33.0 31.7 1.8 8.9 0.9 10.4 3 3 8 11 11 11 4 Anaphase-promoting complex, cyclosome, subunit 3 DUF4404 PF14357.6 EGB06807.1 - 3.5e-06 27.5 5.4 17 6.1 0.1 6.6 6 2 2 8 8 5 0 Domain of unknown function (DUF4404) TPR_4 PF07721.14 EGB06807.1 - 0.00011 22.5 32.4 15 6.5 0.1 12.4 15 0 0 15 15 12 0 Tetratricopeptide repeat CMV_1a_C PF12503.8 EGB06807.1 - 0.0014 18.6 0.0 21 5.2 0.0 4.3 2 2 2 4 4 4 0 Cucumber mosaic virus 1a protein C terminal 14-3-3 PF00244.20 EGB06807.1 - 0.0025 17.4 7.5 2.7 7.5 0.4 5.4 3 2 4 7 7 6 2 14-3-3 protein TPR_9 PF13371.6 EGB06807.1 - 0.071 13.3 25.3 0.44 10.7 0.9 6.8 4 3 3 7 7 7 0 Tetratricopeptide repeat PI3K_P85_iSH2 PF16454.5 EGB06807.1 - 0.074 12.6 0.4 2.4 7.7 0.0 3.6 5 0 0 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tcf25 PF04910.14 EGB06807.1 - 0.14 11.2 0.8 23 3.9 0.0 3.2 4 0 0 4 4 4 0 Transcriptional repressor TCF25 FUR PF01475.19 EGB06807.1 - 0.16 12.1 0.8 2e+02 2.1 0.0 4.3 2 2 2 4 4 4 0 Ferric uptake regulator family Coatomer_E PF04733.14 EGB06807.1 - 0.17 11.3 8.8 18 4.6 0.0 5.6 4 2 3 8 8 8 0 Coatomer epsilon subunit MIT PF04212.18 EGB06807.1 - 0.72 10.0 31.6 49 4.1 0.0 10.9 10 2 2 12 12 11 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGB06807.1 - 1.3 9.8 0.0 1.3 9.8 0.0 13.6 15 0 0 15 15 14 0 Tetratricopeptide repeat GTP1_OBG PF01018.22 EGB06808.1 - 1.4e-48 164.4 1.7 2.1e-48 163.9 1.7 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 EGB06808.1 - 4.3e-20 71.9 0.0 6.8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB06808.1 - 5.6e-08 32.5 0.0 2.3e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EGB06808.1 - 0.0012 18.3 0.1 0.41 10.1 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGB06808.1 - 0.012 15.6 0.2 0.11 12.4 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase cobW PF02492.19 EGB06808.1 - 0.021 14.4 0.0 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EGB06808.1 - 0.031 13.8 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB06808.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MeaB PF03308.16 EGB06808.1 - 0.08 11.9 0.1 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Myosin_head PF00063.21 EGB06809.1 - 5.7e-164 547.0 0.0 6.7e-164 546.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_19 PF13245.6 EGB06809.1 - 0.024 15.0 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB06809.1 - 0.075 13.4 0.2 0.31 11.4 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGB06809.1 - 0.076 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PqiA PF04403.13 EGB06810.1 - 8.5e-18 64.7 15.0 3e-12 46.6 3.2 3.0 2 1 0 2 2 2 2 Paraquat-inducible protein A RicinB_lectin_2 PF14200.6 EGB06810.1 - 6e-09 36.5 1.9 0.00022 21.9 0.1 4.0 5 0 0 5 5 5 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EGB06810.1 - 4.4e-08 33.4 0.1 0.00019 21.7 0.0 3.3 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain Tyrosinase PF00264.20 EGB06810.1 - 0.00015 22.1 1.6 0.00015 22.1 1.6 2.4 2 0 0 2 2 2 1 Common central domain of tyrosinase JHBP PF06585.11 EGB06810.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) LRR_4 PF12799.7 EGB06811.1 - 1.5e-11 44.3 5.6 0.034 14.6 0.1 5.4 2 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB06811.1 - 0.023 14.4 9.4 0.54 10.1 0.7 4.2 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 EGB06811.1 - 0.036 14.6 13.0 8.4 7.4 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 EGB06811.1 - 0.096 12.2 0.4 5.5 6.5 0.0 3.0 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 EGB06811.1 - 4 7.7 6.9 26 5.2 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat PHD PF00628.29 EGB06812.1 - 5.8e-16 58.1 18.8 4.1e-11 42.6 5.8 5.2 3 1 2 5 5 5 3 PHD-finger PHD_4 PF16866.5 EGB06812.1 - 2.8e-05 24.1 4.5 2.8e-05 24.1 4.5 4.6 2 1 2 4 4 4 3 PHD-finger PHD_2 PF13831.6 EGB06812.1 - 0.081 12.5 30.3 0.057 13.0 1.7 4.8 3 1 1 4 4 4 0 PHD-finger zf-HC5HC2H PF13771.6 EGB06813.1 - 1.2e-11 44.7 9.0 1.5e-11 44.4 9.0 1.2 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGB06813.1 - 1.4e-09 38.1 8.4 1.7e-09 37.8 8.4 1.2 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-C2HE PF16278.5 EGB06813.1 - 0.054 13.9 0.0 0.094 13.2 0.0 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger PHD PF00628.29 EGB06813.1 - 0.51 10.3 13.2 1.8 8.5 9.1 2.4 2 1 0 2 2 2 0 PHD-finger SET PF00856.28 EGB06814.1 - 5.4e-18 65.9 0.1 5.2e-17 62.8 0.1 1.9 1 1 0 1 1 1 1 SET domain DUF4176 PF13780.6 EGB06814.1 - 0.017 15.2 0.3 0.051 13.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) DUF1612 PF07756.12 EGB06815.1 - 0.11 12.7 5.1 0.24 11.6 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) Nup192 PF11894.8 EGB06816.1 - 0.0063 13.7 0.0 0.032 11.4 0.0 1.9 3 0 0 3 3 3 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 VCBS PF13517.6 EGB06817.1 - 9.6e-80 263.1 246.5 1.3e-09 38.5 9.4 17.4 3 3 14 17 17 17 17 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AbfS_sensor PF18225.1 EGB06817.1 - 8.3e-11 41.6 0.0 52 3.8 0.0 12.0 13 0 0 13 13 13 0 Sensor histidine kinase (AbfS) sensor domain GPI-anchored PF10342.9 EGB06817.1 - 8e-06 26.5 0.0 0.0027 18.5 0.0 4.3 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pirin_C PF05726.13 EGB06817.1 - 0.0085 16.4 0.1 56 4.2 0.0 6.4 3 2 5 8 8 8 0 Pirin C-terminal cupin domain Dockerin_1 PF00404.18 EGB06817.1 - 0.014 15.5 116.6 4.5 7.5 7.2 16.0 11 6 4 15 15 15 0 Dockerin type I domain HTH_31 PF13560.6 EGB06817.1 - 0.023 15.1 12.0 68 3.9 0.0 9.5 12 0 0 12 12 12 0 Helix-turn-helix domain DSPc PF00782.20 EGB06818.1 - 8.3e-24 83.9 0.0 9.2e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB06818.1 - 0.0028 17.2 0.3 0.01 15.5 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGB06818.1 - 0.0082 16.4 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EGB06818.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.3 1 1 0 1 1 1 0 Inositol hexakisphosphate Aldo_ket_red PF00248.21 EGB06819.1 - 8.8e-40 136.7 0.0 4.8e-38 131.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GDP_Man_Dehyd PF16363.5 EGB06820.1 - 1.7e-52 178.9 0.0 4.4e-52 177.5 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGB06820.1 - 3.2e-47 161.0 0.0 4.1e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB06820.1 - 9.9e-11 41.1 0.0 1.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGB06820.1 - 2.4e-09 36.7 0.0 0.00015 21.1 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EGB06820.1 - 2.4e-08 33.5 0.0 1.8e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGB06820.1 - 4.8e-07 29.2 0.0 6.6e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EGB06820.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 EGB06820.1 - 0.18 11.7 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding AstE_AspA PF04952.14 EGB06821.1 - 3e-08 33.1 0.0 4.1e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 EGB06821.1 - 3.8e-07 29.8 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) Peptidase_M14 PF00246.24 EGB06821.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase PMSR PF01625.21 EGB06822.1 - 1.4e-56 190.9 0.2 2.4e-56 190.2 0.2 1.3 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 EGB06822.1 - 0.017 15.0 0.1 0.045 13.6 0.1 1.7 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Pribosyltran PF00156.27 EGB06823.1 - 1.4e-12 47.4 0.0 2.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_trans_4_4 PF13579.6 EGB06823.1 - 0.0024 18.3 0.0 0.0044 17.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Fe-ADH PF00465.19 EGB06823.1 - 0.016 14.1 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase LETM1 PF07766.13 EGB06824.1 - 6.5e-06 25.7 0.0 0.00012 21.5 0.0 2.0 2 0 0 2 2 2 2 LETM1-like protein SWIRM PF04433.17 EGB06825.1 - 2e-20 72.9 0.0 2.2e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 SWIRM domain ADH_zinc_N PF00107.26 EGB06826.1 - 1.4e-21 76.8 1.2 2.5e-21 76.0 1.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGB06826.1 - 1.1e-13 52.4 0.5 2.7e-13 51.1 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB06826.1 - 7.6e-08 32.2 0.1 4.2e-07 29.8 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EGB06826.1 - 0.0014 18.2 1.5 0.0026 17.3 1.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ATP-grasp_2 PF08442.10 EGB06827.1 - 6e-64 215.3 1.5 9.4e-64 214.7 1.5 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGB06827.1 - 8.3e-26 90.6 2.8 2.4e-25 89.1 2.8 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGB06827.1 - 2.1e-11 43.7 2.1 8.2e-11 41.8 2.1 1.8 1 1 0 1 1 1 1 ATP-grasp domain GTP_EFTU PF00009.27 EGB06828.1 - 7.5e-09 35.4 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB06828.1 - 0.00063 19.7 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 EGB06828.1 - 0.0052 16.9 0.2 0.011 15.9 0.2 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain ATP_bind_1 PF03029.17 EGB06828.1 - 0.013 15.3 0.4 3.9 7.2 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGB06828.1 - 0.075 13.5 0.1 0.14 12.7 0.1 1.3 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EGB06828.1 - 0.093 12.5 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EGB06828.1 - 0.094 12.5 1.4 0.29 10.9 0.2 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB06828.1 - 0.13 12.6 1.9 0.32 11.4 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU_D2 PF03144.25 EGB06828.1 - 0.23 11.8 1.9 0.42 11.0 0.8 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 DEAD PF00270.29 EGB06829.1 - 1.3e-42 145.6 0.0 2.3e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB06829.1 - 8.3e-24 84.1 0.0 1.7e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGB06829.1 - 5.6e-18 64.9 1.5 1.6e-17 63.5 1.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGB06829.1 - 0.003 17.6 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGB06829.1 - 0.0036 16.6 0.0 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase LRR_8 PF13855.6 EGB06830.1 - 8.9e-13 47.8 1.2 7.2e-07 28.9 0.3 2.9 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EGB06830.1 - 2.5e-07 30.9 0.3 1.1 9.8 0.1 4.2 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB06830.1 - 0.002 18.4 0.3 18 6.4 0.1 4.6 4 2 1 5 5 5 2 Leucine Rich Repeat CSTF_C PF14304.6 EGB06831.1 - 1.9e-09 36.9 5.7 0.00062 19.3 0.1 3.3 3 1 1 4 4 4 2 Transcription termination and cleavage factor C-terminal Coatomer_E PF04733.14 EGB06832.1 - 1.3e-86 290.6 2.9 1.5e-86 290.5 2.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 EGB06832.1 - 6.6e-06 26.3 5.1 0.015 15.5 0.3 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGB06832.1 - 0.00014 22.3 16.4 0.00022 21.7 0.8 4.1 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06832.1 - 0.00074 20.1 3.7 0.48 11.4 0.0 4.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06832.1 - 0.00077 19.7 8.3 0.0025 18.1 0.2 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06832.1 - 0.015 15.4 7.1 0.35 11.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB06832.1 - 0.02 15.5 5.6 0.032 14.9 0.1 3.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06832.1 - 0.034 14.2 0.1 0.36 10.9 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06832.1 - 0.27 11.1 3.7 1.2 9.0 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB06832.1 - 0.41 10.6 2.3 0.88 9.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 EGB06833.1 - 6.3e-22 78.6 0.0 1e-21 77.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB06833.1 - 0.00012 22.0 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB06833.1 - 0.00029 20.4 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 EGB06833.1 - 0.0053 16.4 0.0 0.0068 16.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 EGB06833.1 - 0.017 15.5 0.3 0.031 14.7 0.3 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGB06833.1 - 0.037 14.3 0.0 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGB06833.1 - 0.054 13.2 0.1 0.1 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGB06833.1 - 0.097 13.0 0.0 0.26 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EGB06834.1 - 2e-11 44.3 0.1 0.00041 20.9 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB06834.1 - 3.9e-10 40.1 0.5 0.0013 19.3 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB06834.1 - 1.2e-09 38.2 2.0 0.0015 18.8 0.4 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB06834.1 - 8e-08 32.4 0.3 0.0074 16.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGB06834.1 - 0.0031 17.9 0.9 5.1 8.0 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeat MCU PF04678.13 EGB06834.1 - 0.37 10.9 1.6 21 5.2 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Prok-RING_2 PF14445.6 EGB06835.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Glyco_transf_49 PF13896.6 EGB06836.1 - 8.1e-28 97.7 0.0 1.2e-08 34.7 0.0 3.2 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan RAP PF08373.10 EGB06836.1 - 2.3e-18 66.0 0.0 3.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 EGB06836.1 - 2.2e-10 40.3 0.0 0.72 9.8 0.0 7.0 6 3 3 9 9 9 3 FAST kinase-like protein, subdomain 1 2OG-FeII_Oxy_3 PF13640.6 EGB06836.1 - 5.9e-06 27.1 0.0 1.6e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1601 PF07671.11 EGB06836.1 - 1.1e-05 25.2 7.6 1.4 8.9 0.0 7.6 9 0 0 9 9 9 1 Protein of unknown function (DUF1601) SAP PF02037.27 EGB06836.1 - 0.0019 17.9 0.1 0.0036 17.0 0.1 1.5 1 0 0 1 1 1 1 SAP domain 2OG-FeII_Oxy_4 PF13661.6 EGB06836.1 - 0.0056 17.3 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MTES_1575 PF18741.1 EGB06836.1 - 0.064 13.4 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 REase_MTES_1575 Peptidase_M41 PF01434.18 EGB06837.1 - 1.5e-47 161.9 1.5 1.1e-36 126.5 0.1 2.2 1 1 1 2 2 2 2 Peptidase family M41 AAA PF00004.29 EGB06837.1 - 6.1e-47 159.4 0.0 4.2e-44 150.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB06837.1 - 5.5e-11 42.1 0.6 4.5e-10 39.2 0.4 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EGB06837.1 - 4.3e-06 27.2 1.4 6.5e-05 23.4 1.4 2.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGB06837.1 - 1.1e-05 25.2 0.0 0.00016 21.5 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGB06837.1 - 2.5e-05 24.5 0.0 0.0009 19.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGB06837.1 - 6e-05 22.4 0.1 0.00014 21.2 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGB06837.1 - 0.00024 21.4 0.2 0.15 12.4 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EGB06837.1 - 0.00044 20.3 1.2 0.014 15.4 0.5 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EGB06837.1 - 0.00079 19.9 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB06837.1 - 0.0052 16.9 0.0 0.015 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGB06837.1 - 0.0084 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGB06837.1 - 0.013 15.7 0.3 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGB06837.1 - 0.024 14.7 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EGB06837.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGB06837.1 - 0.042 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Peptidase_M50B PF13398.6 EGB06837.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like AAA_18 PF13238.6 EGB06837.1 - 0.069 13.7 0.0 0.17 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB06837.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EGB06839.1 - 2.6e-28 98.8 0.0 3.2e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGB06839.1 - 5.7e-06 25.5 0.2 0.0074 15.3 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGB06839.1 - 0.049 13.5 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 NTPase GHMP_kinases_C PF08544.13 EGB06839.1 - 0.12 12.8 0.0 0.69 10.3 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal NTPase_1 PF03266.15 EGB06840.1 - 2.2e-38 131.8 0.0 2.6e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 EGB06840.1 - 1.7e-06 28.5 0.3 3.5e-06 27.5 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EGB06840.1 - 2.2e-06 27.5 0.6 3.6e-06 26.8 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGB06840.1 - 0.00012 22.5 0.0 0.00023 21.6 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB06840.1 - 0.00018 21.8 0.1 0.00059 20.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGB06840.1 - 0.0021 17.4 0.1 0.011 15.1 0.0 1.9 1 1 1 2 2 2 1 Zeta toxin AAA_25 PF13481.6 EGB06840.1 - 0.0027 17.3 2.4 0.0058 16.2 2.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB06840.1 - 0.0031 18.1 0.0 0.0049 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB06840.1 - 0.0051 17.1 0.1 0.008 16.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGB06840.1 - 0.0066 16.5 0.2 0.044 13.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 EGB06840.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EGB06840.1 - 0.016 15.3 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EGB06840.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EGB06840.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2478 PF10649.9 EGB06840.1 - 0.025 14.2 1.9 0.037 13.6 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2478) TsaE PF02367.17 EGB06840.1 - 0.027 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ArsA_ATPase PF02374.15 EGB06840.1 - 0.033 13.4 0.5 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_14 PF13173.6 EGB06840.1 - 0.039 14.0 0.0 3.2 7.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGB06840.1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 EGB06840.1 - 0.096 12.4 0.1 2 8.1 0.0 2.1 1 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 EGB06840.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EGB06840.1 - 0.19 11.6 0.0 1.6 8.6 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 EGB06840.1 - 0.22 11.0 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EGB06840.1 - 0.28 11.7 0.0 0.31 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Amino_oxidase PF01593.24 EGB06842.1 - 4.7e-56 191.0 5.2 6.1e-56 190.6 5.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB06842.1 - 1.2e-16 60.7 0.6 6.7e-16 58.3 0.4 2.5 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGB06842.1 - 5.4e-06 26.9 1.2 2e-05 25.0 0.7 2.2 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB06842.1 - 8.7e-06 25.2 0.6 4.9e-05 22.7 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB06842.1 - 0.00012 21.7 15.9 0.0011 18.6 15.9 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB06842.1 - 0.002 17.3 2.7 0.0035 16.5 2.7 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EGB06842.1 - 0.0021 18.1 4.0 1.1 9.3 0.1 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EGB06842.1 - 0.0025 16.6 1.8 0.0026 16.5 0.9 1.4 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EGB06842.1 - 0.0048 16.2 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EGB06842.1 - 0.0058 15.9 2.4 0.0063 15.8 1.1 1.6 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 EGB06842.1 - 0.011 15.6 0.8 0.018 14.9 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EGB06842.1 - 0.017 14.5 2.1 0.042 13.2 2.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGB06842.1 - 0.018 14.3 0.1 0.042 13.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DUF347 PF03988.12 EGB06842.1 - 0.023 14.9 1.0 0.16 12.2 0.4 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) GIDA PF01134.22 EGB06842.1 - 0.039 13.0 1.3 0.061 12.4 1.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGB06842.1 - 0.055 12.5 0.3 0.1 11.6 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EGB06842.1 - 0.37 10.0 0.6 0.56 9.4 0.6 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase His_Phos_1 PF00300.22 EGB06843.1 - 2.6e-12 46.8 0.0 8e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DEAD PF00270.29 EGB06844.1 - 1.7e-19 70.3 0.0 2.2e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB06844.1 - 3.6e-11 43.3 0.0 4.3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit YycC PF14174.6 EGB06844.1 - 0.031 14.1 0.1 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 YycC-like protein Zot PF05707.12 EGB06844.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) QRPTase_C PF01729.19 EGB06845.1 - 1.8e-57 193.8 0.4 2.3e-57 193.5 0.4 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGB06845.1 - 3.4e-14 52.7 0.0 7.7e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Beta_helix PF13229.6 EGB06846.1 - 2e-06 27.8 1.1 0.22 11.4 0.2 3.9 4 1 1 5 5 5 3 Right handed beta helix region TPR_19 PF14559.6 EGB06846.1 - 0.00084 19.8 4.0 0.00084 19.8 4.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06846.1 - 0.0014 18.6 0.1 0.0014 18.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06846.1 - 0.002 17.8 0.1 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06846.1 - 0.0038 17.9 3.6 0.0038 17.9 3.6 6.4 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06846.1 - 0.078 13.0 0.2 0.3 11.2 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TRP PF06011.12 EGB06846.1 - 0.09 11.5 3.8 0.052 12.3 0.2 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel TPR_12 PF13424.6 EGB06846.1 - 0.28 11.5 9.0 0.063 13.6 4.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MSC PF09402.10 EGB06846.1 - 1.8 7.9 4.3 3.1 7.2 4.3 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Adaptin_binding PF10199.9 EGB06847.1 - 1.4e-05 25.7 0.0 0.0023 18.5 0.1 2.7 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 TcpQ PF10671.9 EGB06847.1 - 0.12 12.5 0.5 0.99 9.6 0.7 2.2 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q CCDC53 PF10152.9 EGB06847.1 - 1.8 9.0 5.1 0.54 10.7 1.7 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HAD_2 PF13419.6 EGB06848.1 - 6.3e-10 39.4 0.0 8.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB06848.1 - 6.9e-09 36.3 0.1 2.3e-08 34.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosom_S12_S23 PF00164.25 EGB06849.1 - 7.2e-49 164.2 0.7 9.2e-49 163.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 EGB06849.1 - 0.08 12.5 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase SIS PF01380.22 EGB06851.1 - 2e-34 118.3 4.0 1.1e-16 60.9 0.0 3.4 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 EGB06851.1 - 3.6e-20 72.5 0.3 8.3e-20 71.4 0.3 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGB06851.1 - 1.5e-13 50.7 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGB06851.1 - 0.0054 15.7 0.4 0.02 13.8 0.3 1.8 1 1 0 2 2 2 1 Glutamine amidotransferases class-II bact-PGI_C PF10432.9 EGB06851.1 - 0.019 15.0 0.0 0.07 13.2 0.0 1.9 1 1 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain SQHop_cyclase_C PF13243.6 EGB06852.1 - 0.016 14.3 0.7 0.024 13.7 0.5 1.3 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Sulfotransfer_2 PF03567.14 EGB06854.1 - 0.00023 21.2 0.0 0.00065 19.7 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 EGB06854.1 - 0.0044 16.0 3.2 0.005 15.8 0.9 1.8 1 1 1 2 2 2 1 Galactose-3-O-sulfotransferase Pro-kuma_activ PF09286.11 EGB06854.1 - 0.055 13.8 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain S4 PF01479.25 EGB06855.1 - 4.3e-11 42.4 1.0 9.4e-11 41.3 1.0 1.6 1 0 0 1 1 1 1 S4 domain Tubulin PF00091.25 EGB06856.1 - 1.9e-40 139.2 0.6 3e-40 138.5 0.6 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EGB06856.1 - 7.9e-30 103.0 0.2 2e-29 101.7 0.2 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 EGB06856.1 - 4.6 6.3 10.4 1.9 7.6 3.8 2.2 1 1 1 2 2 2 0 Tubulin like Ribosomal_L39 PF00832.20 EGB06857.1 - 2.1e-22 78.5 15.3 2.4e-22 78.3 15.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein DnaJ PF00226.31 EGB06858.1 - 4.9e-21 74.6 0.0 6.3e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Glycolytic PF00274.19 EGB06859.1 - 4.7e-95 318.3 0.0 6.5e-95 317.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Pkinase PF00069.25 EGB06859.1 - 1.3e-51 175.5 0.0 2e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06859.1 - 3e-20 72.6 0.0 5.1e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB06859.1 - 2.7e-09 36.8 0.0 5.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB06859.1 - 2.5e-08 34.2 1.3 0.00067 19.7 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB06859.1 - 3.7e-06 26.0 0.0 6.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGB06859.1 - 0.0007 19.3 0.1 0.34 10.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGB06859.1 - 0.12 11.7 0.1 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGB06859.1 - 0.26 10.9 2.1 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 RIO1 family TTL PF03133.15 EGB06860.1 - 2.1e-71 240.5 0.0 2.6e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGB06860.1 - 6.4e-08 32.2 0.0 4.5e-06 26.1 0.0 2.6 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGB06860.1 - 0.0014 18.0 0.0 0.23 10.7 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RRM_1 PF00076.22 EGB06862.1 - 5.2e-25 87.1 0.1 8.9e-13 47.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGB06862.1 - 1.8e-13 50.1 0.0 8.9e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB06862.1 - 3.3e-07 30.1 0.0 0.00016 21.4 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 EGB06862.1 - 0.012 15.5 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 EGB06862.1 - 0.027 14.5 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Arm PF00514.23 EGB06863.1 - 0.064 13.3 21.5 0.59 10.3 0.1 7.6 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat cNMP_binding PF00027.29 EGB06864.1 - 3.5e-19 68.7 0.0 4.6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain FragX_IP PF05994.11 EGB06865.1 - 1.1e-64 219.0 0.0 8.9e-57 192.8 0.0 3.3 3 1 1 4 4 4 2 Cytoplasmic Fragile-X interacting family MIF4G_like PF09088.11 EGB06867.1 - 2.9e-14 53.3 0.0 4.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EGB06867.1 - 6.9e-09 35.6 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G like Ubiq_cyt_C_chap PF03981.12 EGB06867.1 - 1 9.4 4.3 5.3 7.1 4.3 2.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Rieske PF00355.26 EGB06868.1 - 1.2e-12 47.5 0.0 1.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SspK PF08176.12 EGB06868.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Small acid-soluble spore protein K family Exo_endo_phos PF03372.23 EGB06869.1 - 8.3e-22 77.8 0.2 1.8e-21 76.8 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 EGB06869.1 - 1.7e-05 25.0 8.4 4.6e-05 23.6 8.4 1.8 1 1 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding HPIH PF13323.6 EGB06869.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain with HPIH motif zf-MYND PF01753.18 EGB06869.1 - 0.43 10.7 7.8 1.2 9.3 7.8 1.8 1 0 0 1 1 1 0 MYND finger Hydrolase_4 PF12146.8 EGB06870.1 - 1e-05 24.9 0.0 3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DAGAT PF03982.13 EGB06870.1 - 1.1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 EGB06870.1 - 0.00081 19.0 0.0 0.054 13.1 0.0 2.3 2 0 0 2 2 2 1 Acyltransferase Abhydrolase_1 PF00561.20 EGB06870.1 - 0.0027 17.4 0.0 0.015 14.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGB06870.1 - 0.0038 17.1 0.2 0.0094 15.8 0.2 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 EGB06870.1 - 0.19 11.6 0.0 0.81 9.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) HD_4 PF13328.6 EGB06871.1 - 7.2e-37 126.5 3.1 4.7e-36 123.9 3.1 1.8 1 1 0 1 1 1 1 HD domain HD PF01966.22 EGB06871.1 - 3.9e-07 30.3 0.2 7.6e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 HD domain DUF668 PF05003.12 EGB06871.1 - 0.069 13.6 0.1 0.1 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF668) FERM_F1 PF18379.1 EGB06871.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain GNAT_acetyltran PF12746.7 EGB06871.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase DprA_WH PF17782.1 EGB06871.1 - 0.31 11.2 2.3 0.96 9.6 0.5 2.4 2 1 1 3 3 3 0 DprA winged helix domain SPX PF03105.19 EGB06872.1 - 0.0018 18.3 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 2 SPX domain RRM_1 PF00076.22 EGB06873.1 - 5.5e-16 58.1 0.0 6.5e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E1-E2_ATPase PF00122.20 EGB06875.1 - 2.1e-42 144.7 0.6 2.1e-42 144.7 0.6 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGB06875.1 - 1.1e-33 116.5 4.8 1.3e-19 70.6 0.1 3.4 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGB06875.1 - 1.2e-17 63.8 0.0 2.6e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGB06875.1 - 2.3e-16 59.2 0.0 4.8e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EGB06875.1 - 5.2e-16 59.6 1.3 1.1e-05 25.8 0.0 3.7 3 1 1 4 4 4 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGB06875.1 - 5.3e-05 23.1 0.7 0.0014 18.4 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EGB06875.1 - 5.4 6.8 6.7 1.9 8.2 0.3 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Proteasome PF00227.26 EGB06876.1 - 1.5e-46 158.3 0.0 1.9e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Ank_2 PF12796.7 EGB06877.1 - 2e-20 73.2 1.0 1.8e-11 44.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB06877.1 - 1.6e-18 66.8 1.5 2.1e-09 37.8 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB06877.1 - 7.4e-16 56.7 0.7 0.00013 22.1 0.0 5.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGB06877.1 - 2.2e-14 53.3 6.4 1.6e-06 28.3 0.2 4.6 3 2 2 5 5 5 2 Ankyrin repeats (many copies) TRAM_LAG1_CLN8 PF03798.16 EGB06877.1 - 1e-13 51.5 4.7 1.5e-13 51.0 4.7 1.2 1 0 0 1 1 1 1 TLC domain Ank PF00023.30 EGB06877.1 - 3e-13 49.6 6.3 5.6e-05 23.4 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat LRR_6 PF13516.6 EGB06877.1 - 0.016 15.2 10.0 1.4 9.2 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeat UMPH-1 PF05822.12 EGB06878.1 - 1.3e-45 155.9 0.0 2.1e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 EGB06878.1 - 5.4e-06 26.9 0.3 1.1e-05 25.9 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGB06878.1 - 0.0039 17.3 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TMEM43 PF07787.12 EGB06879.1 - 2.6 7.4 5.0 12 5.2 1.7 2.3 2 0 0 2 2 2 0 Transmembrane protein 43 Trypan_PARP PF05887.11 EGB06880.1 - 7.4e-05 22.7 6.4 0.00076 19.5 1.2 2.3 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) Adeno_E1A PF02703.14 EGB06880.1 - 0.65 9.5 7.7 0.14 11.7 1.7 2.2 2 0 0 2 2 2 0 Early E1A protein TonB_N PF16031.5 EGB06880.1 - 1.4 9.4 24.5 0.6 10.6 9.8 2.5 2 0 0 2 2 2 0 TonB polyproline region SPESP1 PF15754.5 EGB06880.1 - 9.4 5.3 9.4 0.47 9.6 1.9 2.0 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 PP2C PF00481.21 EGB06881.1 - 1e-54 185.9 0.0 4.9e-42 144.4 0.0 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EGB06881.1 - 0.00031 20.7 0.3 0.0058 16.6 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) AAA_12 PF13087.6 EGB06882.1 - 4.1e-25 88.6 0.0 5.9e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNase_H_2 PF13482.6 EGB06882.1 - 1.8e-18 67.1 0.0 2.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 RNase_H superfamily AAA_11 PF13086.6 EGB06882.1 - 1.6e-13 51.1 0.1 4e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGB06882.1 - 3.7e-11 43.1 1.5 3.7e-11 43.1 1.5 2.9 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGB06882.1 - 7.3e-06 25.9 0.0 0.00015 21.6 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EGB06882.1 - 1.7e-05 25.2 0.0 4.8e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EGB06882.1 - 0.00045 20.1 0.1 0.003 17.4 0.1 2.1 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 EGB06882.1 - 0.0031 17.5 0.0 0.0089 16.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EGB06882.1 - 0.0045 17.4 0.4 0.023 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 EGB06882.1 - 0.0049 16.7 0.1 0.028 14.2 0.1 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 EGB06882.1 - 0.0079 15.7 0.0 0.053 13.0 0.1 2.0 2 0 0 2 2 2 1 PhoH-like protein DUF4332 PF14229.6 EGB06882.1 - 0.01 16.1 0.1 0.032 14.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Mg_chelatase PF01078.21 EGB06882.1 - 0.015 14.6 0.1 0.036 13.5 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 EGB06882.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 EGB06882.1 - 0.046 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.6 EGB06882.1 - 0.092 13.4 0.1 0.25 12.0 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain AAA PF00004.29 EGB06882.1 - 0.093 13.2 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGB06882.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 EGB06882.1 - 0.21 10.8 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TMEM189_B_dmain PF10520.9 EGB06883.1 - 6.6e-12 45.9 0.1 1.1e-11 45.2 0.1 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 EGB06883.1 - 0.0014 18.9 4.1 0.0032 17.8 4.1 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily PDGLE PF13190.6 EGB06883.1 - 0.044 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 PDGLE domain HlyIII PF03006.20 EGB06887.1 - 2.1e-26 93.1 18.9 2.8e-26 92.6 18.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related WSD PF15613.6 EGB06887.1 - 4.4e-10 39.9 0.0 1.5e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MBD PF01429.19 EGB06887.1 - 2.2e-06 27.3 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain WHIM1 PF15612.6 EGB06887.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 LRR_6 PF13516.6 EGB06887.1 - 0.85 9.8 2.0 8.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeat DUF4131 PF13567.6 EGB06887.1 - 7.6 6.2 8.6 1.6 8.4 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Prefoldin_2 PF01920.20 EGB06888.1 - 7.5e-19 67.7 8.8 8.7e-19 67.5 8.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit DOCK_N PF16172.5 EGB06888.1 - 0.011 14.7 0.5 2.4 7.0 0.1 2.1 2 0 0 2 2 2 0 DOCK N-terminus EF-hand_1 PF00036.32 EGB06889.1 - 3.2e-16 57.6 7.8 1.8e-05 23.9 0.1 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGB06889.1 - 1e-14 54.7 4.7 5.7e-11 42.7 1.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB06889.1 - 5.8e-14 50.8 6.9 1.9e-05 24.2 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EGB06889.1 - 2.3e-12 45.8 7.3 0.0018 17.7 0.9 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGB06889.1 - 4.6e-10 39.2 9.6 0.0044 16.8 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair APP_N PF02177.16 EGB06889.1 - 0.1 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding EF-hand_4 PF12763.7 EGB06889.1 - 1.9 8.5 6.5 11 6.1 0.1 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand PX PF00787.24 EGB06890.1 - 0.044 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 PX domain Imm75 PF15660.6 EGB06890.1 - 0.094 13.0 0.1 0.094 13.0 0.1 2.5 3 0 0 3 3 3 0 Putative Immunity protein 75 Pannexin_like PF12534.8 EGB06890.1 - 6.3 5.8 4.6 12 4.8 4.6 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 LRR_4 PF12799.7 EGB06891.1 - 1.4e-19 69.8 14.7 3.4e-06 27.3 0.0 6.3 5 1 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB06891.1 - 9.8e-14 51.2 3.6 1.5e-10 40.8 0.2 3.1 2 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 EGB06891.1 - 1.4e-12 47.2 18.3 1.4e-06 28.0 0.1 5.1 4 1 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 EGB06891.1 - 0.013 15.5 11.0 1.5 9.0 0.1 5.9 7 0 0 7 7 7 0 Leucine Rich repeat Nitroreductase PF00881.24 EGB06892.1 - 2.3e-14 53.8 1.0 1.2e-08 35.1 0.2 2.5 1 1 1 2 2 2 2 Nitroreductase family PAP_fibrillin PF04755.12 EGB06892.1 - 9.5e-10 38.7 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin TM1586_NiRdase PF14512.6 EGB06892.1 - 1.6e-05 24.6 0.1 0.013 15.0 0.0 2.2 1 1 1 2 2 2 2 Putative TM nitroreductase SRF-TF PF00319.18 EGB06892.1 - 0.23 11.0 0.5 0.48 10.0 0.5 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) FKBP_C PF00254.28 EGB06893.1 - 3.2e-22 78.7 0.0 3.5e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FAD_binding_7 PF03441.14 EGB06894.1 - 1.7e-32 112.5 0.0 2.1e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase FmdA_AmdA PF03069.15 EGB06894.1 - 0.06 12.2 0.0 0.07 12.0 0.0 1.0 1 0 0 1 1 1 0 Acetamidase/Formamidase family DUF5107 PF17128.4 EGB06895.1 - 7.4e-34 117.3 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5107) SIX1_SD PF16878.5 EGB06895.1 - 0.0011 19.5 0.0 0.015 15.8 0.0 2.3 1 1 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain SPR1 PF15356.6 EGB06895.1 - 0.096 13.2 1.1 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 Nop16 PF09420.10 EGB06896.1 - 2e-21 77.0 6.2 3.2e-13 50.2 0.3 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Pkinase PF00069.25 EGB06897.1 - 5.2e-25 88.3 0.0 6.1e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06897.1 - 1.5e-19 70.3 0.0 1.7e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB06897.1 - 0.0015 18.5 0.2 0.0029 17.6 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 EGB06897.1 - 0.017 14.8 0.0 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 DUF3089 PF11288.8 EGB06898.1 - 3.7e-36 124.5 0.0 6.2e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.8 EGB06898.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB06898.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB06898.1 - 0.13 12.8 10.2 0.27 11.8 10.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family ABC_tran PF00005.27 EGB06899.1 - 2.5e-24 86.4 0.0 3.5e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGB06899.1 - 2e-15 57.2 0.0 3.9e-15 56.2 0.0 1.3 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGB06899.1 - 6.4e-06 25.8 0.2 0.0018 17.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB06899.1 - 0.15 12.4 7.1 0.28 11.5 3.4 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGB06899.1 - 0.19 12.0 1.8 0.27 11.5 0.1 2.1 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 EGB06899.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.6 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fapy_DNA_glyco PF01149.24 EGB06900.1 - 2.8e-13 50.5 0.0 4.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EGB06900.1 - 5.4e-08 32.7 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain SAP PF02037.27 EGB06900.1 - 7.9e-08 31.9 0.2 7.9e-08 31.9 0.2 2.6 3 0 0 3 3 3 1 SAP domain Pkinase PF00069.25 EGB06901.1 - 2.5e-27 95.9 0.0 3.1e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06901.1 - 1.2e-19 70.7 0.0 1.5e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB06901.1 - 0.0098 15.8 0.7 0.07 13.0 0.1 1.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Neur_chan_LBD PF02931.23 EGB06902.1 - 1.1e-14 54.5 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain EF-hand_6 PF13405.6 EGB06902.1 - 3.3e-05 23.5 0.0 0.00016 21.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGB06902.1 - 0.0003 20.1 0.0 0.001 18.4 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EGB06902.1 - 0.00088 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 EF hand Neur_chan_memb PF02932.16 EGB06902.1 - 0.0036 17.4 3.8 0.0077 16.3 3.8 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region EF-hand_7 PF13499.6 EGB06902.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair CAP_N PF01213.19 EGB06902.1 - 2.4 7.6 19.5 0.57 9.6 3.4 2.9 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Glyco_transf_90 PF05686.12 EGB06903.1 - 1.2e-25 90.2 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EGB06903.1 - 1.5e-05 25.3 1.3 3.7e-05 24.0 1.3 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 HSP70 PF00012.20 EGB06904.1 - 3.8e-90 302.8 2.4 4.5e-90 302.6 2.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGB06904.1 - 6.8e-11 41.6 3.7 7.5e-08 31.6 0.6 3.1 3 0 0 3 3 3 3 MreB/Mbl protein StbA PF06406.11 EGB06904.1 - 0.00016 21.0 0.1 0.00059 19.2 0.0 1.8 2 0 0 2 2 2 1 StbA protein BcrAD_BadFG PF01869.20 EGB06904.1 - 0.0044 16.6 1.6 0.063 12.8 1.6 2.6 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family MORN PF02493.20 EGB06905.1 - 6.9e-19 66.5 13.9 1.3e-06 27.9 0.7 3.8 4 0 0 4 4 4 3 MORN repeat DUF3048_C PF17479.2 EGB06905.1 - 0.048 14.1 0.9 0.079 13.3 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain Anoctamin PF04547.12 EGB06906.1 - 3.2e-68 230.6 0.0 6.4e-68 229.6 0.0 1.4 1 1 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 EGB06906.1 - 1.2e-05 25.2 0.0 3.3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin LRR_4 PF12799.7 EGB06907.1 - 2.7e-05 24.4 0.0 0.01 16.2 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB06907.1 - 0.00025 20.7 1.5 0.002 17.9 0.5 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 EGB06907.1 - 0.12 12.5 0.1 23 5.4 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat DEAD PF00270.29 EGB06908.1 - 4.8e-32 111.1 0.0 8.8e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB06908.1 - 2.8e-26 92.0 0.0 1.5e-25 89.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB06908.1 - 0.0027 17.7 0.0 0.0051 16.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGB06908.1 - 0.027 13.8 0.1 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Sulfotransfer_2 PF03567.14 EGB06909.1 - 3.5e-07 30.4 0.0 5.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family FYVE PF01363.21 EGB06910.1 - 6.3e-16 58.3 5.9 7e-16 58.1 5.9 1.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGB06910.1 - 0.00092 19.4 3.6 0.0011 19.1 3.6 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 EGB06910.1 - 0.14 12.4 9.9 0.041 14.1 7.0 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 EGB06910.1 - 1.3 9.3 11.5 0.41 10.9 7.7 2.0 2 1 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 EGB06910.1 - 3.5 7.6 15.5 1.2 9.2 7.4 2.4 1 1 1 2 2 2 0 SprT-like zinc ribbon domain XPA_N PF01286.18 EGB06910.1 - 9 6.4 13.3 6.5 6.9 0.7 3.6 3 1 1 4 4 4 0 XPA protein N-terminal Aldo_ket_red PF00248.21 EGB06911.1 - 3.1e-51 174.3 0.0 3.5e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myosin_head PF00063.21 EGB06912.1 - 3.7e-155 517.9 0.0 4.4e-155 517.6 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_4 PF13637.6 EGB06912.1 - 8.2e-10 39.0 0.1 0.012 16.2 0.0 4.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB06912.1 - 2e-07 31.5 0.1 0.062 13.9 0.0 3.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGB06912.1 - 1.7e-06 28.2 4.3 0.003 18.0 0.1 5.2 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EGB06912.1 - 3.4e-05 24.0 8.3 0.098 13.0 0.2 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB06912.1 - 0.00019 21.6 0.6 0.26 11.9 0.0 4.3 3 0 0 3 3 3 1 Ankyrin repeat AAA_16 PF13191.6 EGB06912.1 - 0.00026 21.4 0.1 0.00026 21.4 0.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB06912.1 - 0.013 15.8 0.0 0.041 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGB06912.1 - 0.075 12.3 0.1 0.17 11.1 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin IBR PF01485.21 EGB06913.1 - 9e-07 29.0 38.4 4.7e-05 23.5 0.9 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain Rad50_zn_hook PF04423.14 EGB06913.1 - 0.027 14.3 1.2 2.5 8.0 0.0 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif Chorismate_bind PF00425.18 EGB06915.1 - 4.8e-81 272.1 0.0 6.3e-81 271.7 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EGB06915.1 - 3.7e-30 105.1 0.0 6.8e-30 104.3 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGB06915.1 - 3.5e-07 30.2 0.0 6.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.13 EGB06915.1 - 1.7e-06 28.3 0.0 5.3e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Kinesin PF00225.23 EGB06916.1 - 1e-85 287.6 0.0 1.8e-85 286.8 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB06916.1 - 1.3e-20 73.8 0.0 2.3e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding PI_PP_C PF18365.1 EGB06916.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain HSP33 PF01430.19 EGB06917.1 - 6.1e-54 183.2 0.0 7.2e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Hsp33 protein HU-CCDC81_euk_1 PF14908.6 EGB06919.1 - 5.4e-16 58.5 0.0 1.3e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 EGB06919.1 - 7.1e-09 35.7 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 Meis_PKNOX_N PF16493.5 EGB06919.1 - 0.17 12.3 0.7 0.36 11.2 0.7 1.6 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Glyco_hydro_28 PF00295.17 EGB06920.1 - 3.9e-08 32.7 0.0 1.6e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4239 PF14023.6 EGB06920.1 - 2.6e-07 30.6 0.0 9.3e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4239) Pectate_lyase_3 PF12708.7 EGB06920.1 - 5e-06 26.5 0.0 0.00054 19.9 0.0 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGB06920.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Mito_carr PF00153.27 EGB06921.1 - 2.1e-48 162.2 4.2 7.2e-17 61.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Nuc_sug_transp PF04142.15 EGB06922.1 - 2.3e-50 171.6 3.1 2.8e-50 171.3 3.1 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB06922.1 - 5.9e-06 26.5 20.8 0.00018 21.7 4.0 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGB06922.1 - 0.00036 19.9 3.5 0.17 11.1 0.6 2.1 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.16 EGB06922.1 - 0.015 14.7 7.0 0.14 11.5 0.8 2.5 2 0 0 2 2 2 0 Triose-phosphate Transporter family P34-Arc PF04045.14 EGB06923.1 - 2e-66 224.2 0.0 2.4e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc MORN PF02493.20 EGB06924.1 - 7.1e-13 47.6 32.4 0.00025 20.8 0.6 6.5 7 0 0 7 7 7 6 MORN repeat Peptidase_S9 PF00326.21 EGB06925.1 - 4.1e-45 153.8 0.0 6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EGB06925.1 - 2e-12 47.1 0.0 3.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EGB06925.1 - 3.3e-05 23.3 0.4 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 SGL PF08450.12 EGB06925.1 - 5.5e-05 22.9 0.0 0.00038 20.1 0.0 2.1 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Abhydrolase_2 PF02230.16 EGB06925.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PD40 PF07676.12 EGB06925.1 - 0.0033 17.3 0.0 0.077 13.0 0.0 3.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_4 PF08386.10 EGB06925.1 - 0.0046 17.1 0.0 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_3 PF07859.13 EGB06925.1 - 0.013 15.3 0.6 0.069 13.0 0.6 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EGB06925.1 - 0.018 14.7 0.0 0.045 13.4 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PAE PF03283.13 EGB06925.1 - 0.32 10.1 0.3 0.59 9.2 0.3 1.3 1 0 0 1 1 1 0 Pectinacetylesterase Peptidase_S10 PF00450.22 EGB06926.1 - 5.7e-88 296.1 0.0 6.9e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EGB06926.1 - 0.05 14.2 2.5 0.34 11.5 2.2 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Vta1 PF04652.16 EGB06927.1 - 1.7e-40 138.3 2.3 1.7e-40 138.3 2.3 1.5 2 0 0 2 2 2 1 Vta1 like Ank_4 PF13637.6 EGB06928.1 - 7e-15 55.2 0.2 5.5e-06 26.8 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB06928.1 - 1.9e-13 50.8 0.1 2.2e-13 50.6 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB06928.1 - 1.3e-10 40.6 0.1 0.0042 17.5 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB06928.1 - 3.1e-10 40.1 0.1 8e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB06928.1 - 1.7e-07 31.4 1.2 0.00019 21.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Sod_Cu PF00080.20 EGB06929.1 - 1.4e-36 125.8 0.4 1.6e-36 125.6 0.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) WD40 PF00400.32 EGB06930.1 - 0.0049 17.7 0.0 1.8 9.5 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB06930.1 - 0.17 12.2 0.0 0.99 9.8 0.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_6 PF12697.7 EGB06932.1 - 2.8e-11 44.4 19.0 7.7e-10 39.7 8.7 3.0 1 1 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB06932.1 - 1.3e-10 40.9 0.0 3.6e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB06932.1 - 2e-09 37.5 0.0 1.8e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EGB06932.1 - 0.00016 21.9 0.1 0.0003 21.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGB06932.1 - 0.00036 20.3 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 EGB06932.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.12 EGB06932.1 - 0.031 14.2 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 EGB06932.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EGB06932.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF915 PF06028.11 EGB06932.1 - 0.23 10.8 0.0 0.47 9.7 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) SF3b10 PF07189.11 EGB06933.1 - 2.8e-35 120.3 0.0 3.1e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Glyco_transf_20 PF00982.21 EGB06934.1 - 1.2e-91 307.8 0.0 1.7e-91 307.3 0.0 1.2 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGB06935.1 - 9.5e-20 70.7 0.0 1.1e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase S6PP PF05116.13 EGB06935.1 - 8.2e-06 25.5 0.0 9.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 EGB06935.1 - 1.4e-05 25.0 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase U-box PF04564.15 EGB06936.1 - 2.6e-13 49.9 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain HECT PF00632.25 EGB06937.1 - 1.4e-60 205.4 0.0 1.7e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3824 PF12868.7 EGB06937.1 - 0.14 12.8 1.3 0.38 11.4 1.3 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) ABC_tran PF00005.27 EGB06938.1 - 9.3e-22 78.0 0.0 1.7e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB06938.1 - 1.1e-05 25.4 0.0 0.0055 16.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB06938.1 - 1.8e-05 24.3 0.2 0.0095 15.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB06938.1 - 0.00017 21.2 0.7 0.00045 19.9 0.7 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB06938.1 - 0.00021 21.7 0.1 0.00045 20.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGB06938.1 - 0.00023 20.8 0.1 0.00077 19.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGB06938.1 - 0.0021 18.4 0.0 0.0039 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGB06938.1 - 0.01 15.8 0.4 0.026 14.4 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase ABC2_membrane PF01061.24 EGB06938.1 - 0.012 15.1 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 ABC-2 type transporter NACHT PF05729.12 EGB06938.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 EGB06938.1 - 0.055 13.6 0.9 0.093 12.8 0.9 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 EGB06938.1 - 0.075 12.8 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_23 PF13476.6 EGB06938.1 - 0.22 12.0 0.0 0.37 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain PAS PF00989.25 EGB06939.1 - 5e-172 561.3 13.1 3.1e-21 75.5 0.0 9.4 9 0 0 9 9 9 9 PAS fold PAS_4 PF08448.10 EGB06939.1 - 5.6e-108 354.9 11.3 5.6e-13 49.1 0.0 9.8 10 0 0 10 10 9 9 PAS fold PAS_9 PF13426.7 EGB06939.1 - 1.5e-99 327.2 23.2 1.8e-12 47.4 0.1 9.2 9 0 0 9 9 9 9 PAS domain PAS_3 PF08447.12 EGB06939.1 - 1.6e-63 211.0 0.0 2.8e-07 30.7 0.0 9.4 9 0 0 9 9 9 9 PAS fold PAS_8 PF13188.7 EGB06939.1 - 1.4e-23 82.4 10.5 0.0062 16.5 0.0 8.5 8 0 0 8 8 8 6 PAS domain PAS_10 PF13596.6 EGB06939.1 - 2e-17 63.7 13.2 0.013 16.1 0.0 9.1 9 0 0 9 9 9 4 PAS domain DUF3189 PF11385.8 EGB06939.1 - 3.2e-17 62.7 2.1 0.35 10.7 0.0 8.4 9 0 0 9 9 9 4 Protein of unknown function (DUF3189) HATPase_c PF02518.26 EGB06939.1 - 5.1e-09 36.6 0.0 2e-08 34.7 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGB06939.1 - 9.1e-07 29.0 0.1 0.011 15.9 0.1 2.8 2 0 0 2 2 2 2 Response regulator receiver domain Tape_meas_lam_C PF09718.10 EGB06939.1 - 0.00018 21.6 1.0 31 4.8 0.0 7.3 9 0 0 9 9 9 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF5588 PF17826.1 EGB06939.1 - 0.00043 19.3 0.1 3.8 6.3 0.0 5.5 6 0 0 6 6 6 1 Family of unknown function (DUF5588) HisKA PF00512.25 EGB06939.1 - 0.0046 17.0 0.1 0.021 14.9 0.1 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Peptidase_M7 PF02031.16 EGB06939.1 - 0.014 15.5 0.7 2e+02 2.1 0.0 6.1 8 0 0 8 8 8 0 Streptomyces extracellular neutral proteinase (M7) family GARS_C PF02843.16 EGB06939.1 - 0.024 14.9 15.2 19 5.6 0.0 7.9 8 0 0 8 8 8 0 Phosphoribosylglycinamide synthetase, C domain SAPI PF16560.5 EGB06939.1 - 0.026 14.1 3.7 63 3.0 0.0 5.0 6 0 0 6 6 6 0 Putative mobile pathogenicity island PseudoU_synth_1 PF01416.20 EGB06939.1 - 0.11 13.0 0.1 4.1 7.9 0.0 3.7 3 1 0 3 3 2 0 tRNA pseudouridine synthase HlyD PF00529.20 EGB06939.1 - 0.83 9.6 23.8 18 5.3 0.1 7.9 9 0 0 9 9 9 0 HlyD membrane-fusion protein of T1SS Cache_3-Cache_2 PF17201.4 EGB06939.1 - 1.9 7.7 9.8 76 2.4 0.0 6.3 8 0 0 8 8 8 0 Cache 3/Cache 2 fusion domain Redoxin PF08534.10 EGB06940.1 - 4.8e-17 62.1 0.0 6.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGB06940.1 - 1.5e-09 37.8 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Pkinase PF00069.25 EGB06941.1 - 3.6e-61 206.8 0.0 4e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06941.1 - 5.5e-40 137.3 0.0 6.1e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB06941.1 - 9.3e-08 31.7 0.0 3.2e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB06941.1 - 0.0013 17.6 0.0 0.0027 16.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGB06941.1 - 0.013 15.4 0.4 3.3 7.6 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family F420_oxidored PF03807.17 EGB06941.1 - 0.099 13.2 0.1 0.26 11.9 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Haspin_kinase PF12330.8 EGB06941.1 - 0.21 10.5 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Chloroa_b-bind PF00504.21 EGB06942.1 - 1.7e-26 93.6 1.4 2.3e-26 93.2 1.4 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Tweety PF04906.13 EGB06943.1 - 2.1e-07 30.0 7.5 3.8e-07 29.1 7.5 1.3 1 1 0 1 1 1 1 Tweety NPV_P10 PF05531.12 EGB06943.1 - 0.00013 22.4 0.5 0.037 14.5 0.1 2.9 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EGB06943.1 - 0.00062 20.0 0.3 0.52 10.6 0.1 3.1 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EGB06943.1 - 0.013 15.5 0.0 1.3 9.1 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EGB06943.1 - 0.018 13.1 12.7 0.96 7.3 0.0 2.5 2 1 0 2 2 2 0 Prominin Serinc PF03348.15 EGB06943.1 - 0.36 9.7 3.7 0.65 8.9 3.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2403 PF10290.9 EGB06944.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 Glycine-rich protein domain (DUF2403) Glyco_hydro_18 PF00704.28 EGB06945.1 - 0.044 13.5 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Exostosin PF03016.15 EGB06947.1 - 2.1e-17 63.3 0.0 5.3e-17 62.0 0.0 1.6 1 1 0 1 1 1 1 Exostosin family Nterm_IS4 PF13006.7 EGB06947.1 - 0.0072 16.5 1.3 3 8.1 0.3 2.7 1 1 1 2 2 2 2 Insertion element 4 transposase N-terminal PRIMA1 PF16101.5 EGB06948.1 - 1.5 8.9 5.4 3.6 7.7 0.3 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Ribosomal_L6 PF00347.23 EGB06949.1 - 5.3e-24 84.7 0.4 1.4e-14 54.5 0.2 2.4 2 1 0 2 2 2 2 Ribosomal protein L6 HD PF01966.22 EGB06950.1 - 1.3e-12 48.0 0.5 6.1e-11 42.6 0.0 2.8 2 2 0 2 2 2 2 HD domain PMSR PF01625.21 EGB06951.1 - 3.8e-51 173.3 0.1 4.5e-51 173.0 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Methyltransf_24 PF13578.6 EGB06952.1 - 5.5e-17 62.7 0.0 1.8e-16 61.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EGB06952.1 - 0.0043 16.3 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase TetR_C_7 PF14246.6 EGB06952.1 - 0.4 10.7 3.9 3 7.9 0.1 2.8 3 0 0 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain GST_C_3 PF14497.6 EGB06953.1 - 2.2e-16 59.9 0.1 3.9e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB06953.1 - 2.3e-07 31.1 0.0 6.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB06953.1 - 0.00055 19.9 0.6 0.0016 18.4 0.6 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGB06953.1 - 0.0016 19.0 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB06953.1 - 0.029 14.6 0.1 0.054 13.7 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 EGB06954.1 - 9.2e-05 23.0 0.0 0.00011 22.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter EPSP_synthase PF00275.20 EGB06955.1 - 0.016 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF2268 PF10026.9 EGB06955.1 - 0.025 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Glyco_transf_41 PF13844.6 EGB06956.1 - 1.1e-30 106.5 0.0 2.5e-17 62.5 0.0 3.4 3 1 0 3 3 3 3 Glycosyl transferase family 41 TFIIA PF03153.13 EGB06956.1 - 0.014 15.4 15.2 0.021 14.8 15.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 EGB06956.1 - 0.11 11.4 5.0 0.16 10.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF627 PF04781.12 EGB06956.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) RNA_pol_3_Rpc31 PF11705.8 EGB06956.1 - 0.18 12.0 23.7 0.38 11.0 23.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Glyco_transf_4 PF13439.6 EGB06956.1 - 0.19 11.7 2.5 0.47 10.4 2.5 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 CDC27 PF09507.10 EGB06956.1 - 0.95 8.8 17.1 1.5 8.2 17.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 EGB06956.1 - 1.7 8.1 20.6 2.7 7.5 20.6 1.3 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 EGB06956.1 - 2.5 7.5 25.7 4.8 6.5 25.7 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGB06956.1 - 3.7 5.6 30.3 5.4 5.1 30.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EGB06956.1 - 5.3 6.8 16.7 10 5.8 16.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EGB06956.1 - 6.7 4.9 18.0 11 4.2 18.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF616 PF04765.13 EGB06957.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF616) Mito_carr PF00153.27 EGB06958.1 - 1.2e-17 63.6 5.5 4.9e-06 26.4 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.7 EGB06959.1 - 7.3e-07 29.7 0.0 1.7e-05 25.3 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB06959.1 - 6.8e-06 26.3 1.3 0.0038 17.5 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB06959.1 - 0.00021 21.8 0.1 0.76 10.4 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TPR_1 PF00515.28 EGB06959.1 - 0.0026 17.5 5.3 0.033 14.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Ank PF00023.30 EGB06959.1 - 0.0031 17.9 0.9 2.7 8.6 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat TPR_2 PF07719.17 EGB06959.1 - 0.0034 17.4 7.7 0.15 12.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Ank_3 PF13606.6 EGB06959.1 - 0.0048 17.3 0.5 5.3 8.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat TPR_12 PF13424.6 EGB06959.1 - 0.0059 16.9 0.7 0.017 15.4 0.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGB06959.1 - 0.13 12.9 1.1 3.1 8.7 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGB06960.1 - 0.00014 22.4 0.0 0.00053 20.5 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Dimer_Tnp_hAT PF05699.14 EGB06960.1 - 0.00067 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ank PF00023.30 EGB06960.1 - 0.00071 19.9 2.9 0.26 11.8 0.0 3.3 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EGB06960.1 - 0.0023 18.3 0.1 0.94 10.3 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Gly-zipper_Omp PF13488.6 EGB06960.1 - 0.007 16.3 11.8 0.007 16.3 11.8 2.0 2 0 0 2 2 2 1 Glycine zipper Ank_5 PF13857.6 EGB06960.1 - 0.015 15.6 3.5 0.024 14.9 0.1 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DNA_pol3_a_NI PF14480.6 EGB06960.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I Gly-zipper_YMGG PF13441.6 EGB06960.1 - 0.36 10.6 14.8 1.1 9.0 14.7 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 EGB06960.1 - 0.37 10.7 13.2 1 9.3 13.2 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain SET PF00856.28 EGB06961.1 - 4.5e-08 33.7 0.0 3.9e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.6 EGB06961.1 - 3.1e-07 30.0 0.4 0.00021 20.9 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 EGB06961.1 - 3.5e-05 23.9 0.1 0.018 15.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB06961.1 - 7.4e-05 22.6 7.3 0.01 15.9 0.0 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06961.1 - 0.00018 21.2 0.2 0.048 13.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06961.1 - 0.0016 19.1 0.1 0.0016 19.1 0.1 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB06961.1 - 0.0067 16.9 0.1 0.0067 16.9 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB06961.1 - 0.032 14.9 0.2 0.032 14.9 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06961.1 - 0.11 12.6 2.6 0.18 11.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06961.1 - 0.13 12.5 3.4 12 6.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 EGB06962.1 - 1.3e-08 35.4 1.7 0.00056 20.6 0.1 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGB06962.1 - 2.1e-05 25.2 0.1 0.044 14.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGB06962.1 - 5.3e-05 23.8 0.6 0.34 11.6 0.1 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_24 PF13578.6 EGB06962.1 - 0.00037 21.5 4.8 0.11 13.5 0.2 3.5 3 0 0 3 3 3 2 Methyltransferase domain Peptidase_S9 PF00326.21 EGB06962.1 - 0.0065 16.0 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PCMT PF01135.19 EGB06962.1 - 0.026 14.3 0.3 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FA_hydroxylase PF04116.13 EGB06963.1 - 5.6e-20 72.0 10.5 7.1e-20 71.7 10.5 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Transp_cyt_pur PF02133.15 EGB06963.1 - 0.049 12.4 2.0 0.062 12.1 2.0 1.0 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin SAM_1 PF00536.30 EGB06964.1 - 2.4e-09 37.5 0.0 0.00018 21.9 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGB06964.1 - 2.5e-07 30.7 0.0 0.007 16.4 0.1 2.3 1 1 1 2 2 2 2 SAM domain (Sterile alpha motif) E1-E2_ATPase PF00122.20 EGB06966.1 - 4.4e-37 127.3 0.8 4.4e-37 127.3 0.8 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGB06966.1 - 4.5e-18 66.3 0.4 8.3e-18 65.4 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGB06966.1 - 1.4e-10 40.6 3.8 1.6e-10 40.5 0.1 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGB06966.1 - 0.0021 17.8 0.2 0.0046 16.7 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Thioredoxin PF00085.20 EGB06967.1 - 1.2e-13 50.9 0.0 1.3e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB06967.1 - 0.0027 18.1 0.0 0.0064 16.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGB06967.1 - 0.0088 16.0 0.0 0.0097 15.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGB06967.1 - 0.053 13.2 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 EGB06967.1 - 0.072 13.4 0.0 0.15 12.4 0.0 1.6 1 1 1 2 2 2 0 Thioredoxin-like HyaE PF07449.11 EGB06967.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE NAD_binding_5 PF07994.12 EGB06969.1 - 2.7e-50 171.6 0.0 3.2e-49 168.0 0.0 1.9 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGB06969.1 - 8.6e-26 90.3 0.0 1.4e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase G3P_antiterm PF04309.12 EGB06969.1 - 0.047 13.1 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator EGF_2 PF07974.13 EGB06970.1 - 3.8e-14 52.7 49.1 5.9e-05 23.4 5.5 5.5 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 EGB06970.1 - 0.014 15.6 43.1 0.039 14.1 7.7 4.5 3 1 1 4 4 4 0 Laminin EGF domain EGF PF00008.27 EGB06970.1 - 0.68 10.3 48.6 0.34 11.2 6.5 6.3 7 0 0 7 7 7 0 EGF-like domain DUF3054 PF11255.8 EGB06971.1 - 0.039 14.5 0.9 0.082 13.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) Pro_isomerase PF00160.21 EGB06973.1 - 9e-17 61.8 0.0 1.1e-16 61.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CRT-like PF08627.10 EGB06974.1 - 1.5e-87 293.7 0.9 1.7e-87 293.5 0.9 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 EGB06974.1 - 4e-07 29.5 1.1 2.4e-06 27.0 1.1 2.2 1 1 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 EGB06974.1 - 0.3 10.6 6.1 0.044 13.3 0.8 2.0 2 0 0 2 2 2 0 Solute carrier family 35 Methyltransf_21 PF05050.12 EGB06975.1 - 3.8e-06 27.0 0.0 6.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain FHA PF00498.26 EGB06976.1 - 1.3e-15 57.4 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGB06976.1 - 9.4e-07 29.1 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-CCHC PF00098.23 EGB06976.1 - 1.2 9.4 9.1 0.072 13.2 3.2 2.2 2 0 0 2 2 2 0 Zinc knuckle RIO1 PF01163.22 EGB06977.1 - 2.9e-68 229.2 0.0 3.9e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGB06977.1 - 1.7e-06 28.2 2.6 5.7e-06 26.4 2.6 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGB06977.1 - 0.0004 19.8 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGB06977.1 - 0.0036 16.7 0.2 0.4 10.0 0.1 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB06977.1 - 0.024 13.4 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGB06977.1 - 0.053 12.8 0.0 0.053 12.8 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase RAI1 PF08652.11 EGB06978.1 - 1.2e-19 70.3 0.0 1.9e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease VCBS PF13517.6 EGB06979.1 - 3e-43 146.2 96.1 1.7e-09 38.2 10.5 6.7 2 1 5 7 7 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.18 EGB06979.1 - 0.00022 21.4 42.9 2.7 8.3 0.3 7.2 6 1 1 7 7 7 4 Dockerin type I domain nsp9 PF08710.10 EGB06979.1 - 0.00035 20.9 3.6 9.2 6.7 0.0 5.3 3 2 3 6 6 6 1 nsp9 replicase HTH_31 PF13560.6 EGB06979.1 - 0.00093 19.5 0.2 25 5.3 0.0 5.5 7 0 0 7 7 7 0 Helix-turn-helix domain AbfS_sensor PF18225.1 EGB06979.1 - 0.004 17.0 0.0 39 4.2 0.0 5.3 7 0 0 7 7 7 0 Sensor histidine kinase (AbfS) sensor domain CbiA PF01656.23 EGB06979.1 - 0.012 15.6 3.6 5.3 7.1 0.1 4.5 3 3 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4366 PF14283.6 EGB06979.1 - 0.016 15.2 0.1 0.048 13.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) vWF_A PF12450.8 EGB06979.1 - 0.02 14.8 6.1 28 4.7 0.0 6.1 7 0 0 7 7 7 0 von Willebrand factor RBDV_coat PF06593.11 EGB06979.1 - 0.073 12.5 6.8 21 4.5 0.2 4.1 3 3 1 4 4 4 0 Raspberry bushy dwarf virus coat protein Hydrolase_4 PF12146.8 EGB06979.1 - 0.086 12.1 5.2 6.9 5.9 0.0 4.3 5 1 1 6 6 6 0 Serine aminopeptidase, S33 DUF3927 PF13064.6 EGB06979.1 - 0.18 11.8 4.6 32 4.6 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3927) NUDIX-like PF09296.11 EGB06979.1 - 0.2 12.4 1.1 99 3.7 0.2 4.3 2 2 0 2 2 2 0 NADH pyrophosphatase-like rudimentary NUDIX domain EF-hand_5 PF13202.6 EGB06979.1 - 2.5 7.7 52.8 3.4 7.3 0.7 7.6 7 0 0 7 7 7 0 EF hand SUKH_6 PF14568.6 EGB06979.1 - 6.4 7.2 7.2 7.5 7.0 0.2 3.7 3 1 0 3 3 3 0 SMI1-KNR4 cell-wall Cytochrom_C PF00034.21 EGB06981.1 - 1.5e-12 48.5 0.9 2.3e-12 47.9 0.9 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGB06981.1 - 3.7e-05 24.0 4.4 0.00026 21.2 4.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGB06981.1 - 0.036 13.8 0.7 0.12 12.1 0.5 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 EGB06981.1 - 0.23 11.8 2.1 9.2 6.6 0.5 2.2 1 1 1 2 2 2 0 Cytochrome P460 Pkinase PF00069.25 EGB06982.1 - 2.4e-32 112.3 0.0 5.6e-32 111.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB06982.1 - 1.2e-12 47.7 0.0 4.3e-10 39.3 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EGB06982.1 - 4.2e-06 26.9 0.7 0.00022 21.3 0.3 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB06982.1 - 5.8e-06 25.8 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB06982.1 - 0.059 12.1 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Bestrophin PF01062.21 EGB06983.1 - 1e-36 126.9 0.0 1.4e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ion_trans PF00520.31 EGB06984.1 - 3e-17 62.7 4.1 4.7e-17 62.0 4.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB06984.1 - 1.7e-07 31.1 3.0 1.7e-07 31.1 3.0 2.0 2 0 0 2 2 2 1 Ion channel DENN PF02141.21 EGB06984.1 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EGB06984.1 - 0.16 12.7 0.0 0.38 11.5 0.0 1.6 1 0 0 1 1 1 0 uDENN domain EF-hand_1 PF00036.32 EGB06985.1 - 6.6e-15 53.5 3.9 7.5e-07 28.3 1.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB06985.1 - 3.3e-12 46.7 1.9 3.7e-12 46.5 1.9 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB06985.1 - 2e-11 42.9 1.6 4.7e-06 26.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB06985.1 - 6.9e-10 38.6 5.8 0.00015 21.6 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB06985.1 - 5.3e-08 32.0 2.3 0.0052 16.2 0.2 2.6 2 1 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EGB06985.1 - 0.002 18.1 0.1 0.0026 17.7 0.1 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGB06985.1 - 0.0041 16.9 1.9 0.62 10.0 0.3 2.3 1 1 1 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGB06985.1 - 0.035 14.4 0.1 0.045 14.1 0.1 1.1 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 EGB06985.1 - 0.064 13.2 0.1 0.079 12.9 0.1 1.3 1 1 0 1 1 1 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGB06985.1 - 0.082 13.2 0.4 0.092 13.1 0.4 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.11 EGB06985.1 - 0.09 13.3 0.1 0.11 13.0 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like ADP_ribosyl_GH PF03747.14 EGB06986.1 - 1.9e-41 142.7 3.8 1.6e-40 139.6 3.8 1.9 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase Pea-VEAacid PF08111.11 EGB06986.1 - 0.027 14.8 0.6 0.077 13.3 0.6 1.7 1 0 0 1 1 1 0 Pea-VEAacid family SicP-binding PF09119.10 EGB06986.1 - 0.36 10.9 1.3 16 5.6 0.0 3.0 2 1 1 3 3 3 0 SicP binding TMEM154 PF15102.6 EGB06987.1 - 0.00053 19.9 0.0 0.00053 19.9 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 EGB06987.1 - 0.093 13.6 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YopE_N PF09020.10 EGB06987.1 - 0.11 12.7 0.0 0.47 10.7 0.0 2.1 1 0 0 1 1 1 0 YopE, N terminal CD34_antigen PF06365.12 EGB06987.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TPR_2 PF07719.17 EGB06988.1 - 2.9e-09 36.3 16.1 0.0071 16.4 0.2 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB06988.1 - 1.5e-07 31.1 4.6 0.13 12.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB06988.1 - 7.2e-07 28.8 12.0 0.019 14.8 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB06988.1 - 2.8e-05 24.3 17.2 0.00025 21.2 1.9 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB06988.1 - 0.00038 20.9 3.4 2.8 8.8 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB06988.1 - 0.0053 17.5 18.8 0.52 11.3 0.3 6.5 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB06988.1 - 0.052 13.6 3.7 8 6.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB06988.1 - 0.12 12.3 4.8 1.2 9.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PGI PF00342.19 EGB06990.1 - 1e-136 456.4 0.0 6.1e-103 345.0 0.0 2.1 1 1 1 2 2 2 2 Phosphoglucose isomerase Peptidase_M17 PF00883.21 EGB06991.1 - 3.3e-115 384.7 2.0 3.7e-115 384.5 2.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain ArfGap PF01412.18 EGB06992.1 - 4.1e-40 136.5 1.6 4.5e-40 136.4 1.6 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Sod_Fe_C PF02777.18 EGB06993.1 - 4.9e-37 126.2 0.1 7.2e-37 125.7 0.1 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGB06993.1 - 1.2e-24 86.5 0.1 2.4e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CN_hydrolase PF00795.22 EGB06994.1 - 2.6e-38 131.9 0.0 3.5e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L14e PF01929.17 EGB06995.1 - 6.1e-33 113.1 7.4 8e-33 112.8 7.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EGB06995.1 - 0.016 15.1 0.3 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 KOW motif Peptidase_C15 PF01470.17 EGB06996.1 - 2.6e-17 63.7 0.0 3.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Pyroglutamyl peptidase PTH2 PF01981.16 EGB06997.1 - 4.2e-37 127.0 0.0 4.8e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Glutaredoxin PF00462.24 EGB06998.1 - 3e-19 69.0 0.0 4.6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 EGB06998.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.6 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein EF-hand_7 PF13499.6 EGB06999.1 - 2.1e-05 24.9 1.1 0.13 12.7 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB06999.1 - 0.00048 19.9 0.1 4.5 7.5 0.0 3.7 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGB06999.1 - 0.029 13.9 0.7 3.3 7.5 0.0 3.4 3 0 0 3 3 3 0 EF hand Metallophos PF00149.28 EGB07000.1 - 2.5e-08 34.7 0.0 4.7e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB07000.1 - 4e-08 33.6 0.0 0.00087 19.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Ank_5 PF13857.6 EGB07003.1 - 1.1e-12 47.9 0.2 4.5e-08 33.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB07003.1 - 5.3e-12 46.2 0.1 6.5e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB07003.1 - 5.6e-12 45.9 0.3 6.4e-11 42.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB07003.1 - 6.7e-11 41.4 0.1 1.3e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EGB07003.1 - 2.2e-08 34.2 1.0 0.0053 17.2 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Thioredoxin PF00085.20 EGB07004.1 - 0.006 16.5 0.0 0.0066 16.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 EGB07004.1 - 0.016 15.4 0.0 4.9 7.3 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin TrmO PF01980.16 EGB07007.1 - 7.1e-37 126.3 0.0 1.3e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O Cupin_8 PF13621.6 EGB07007.1 - 5.4e-21 75.4 0.0 2.8e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EGB07007.1 - 0.0063 16.2 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 EGB07007.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein DUF4461 PF14688.6 EGB07007.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) Na_Ca_ex PF01699.24 EGB07009.1 - 2.7e-23 82.6 10.2 3.7e-23 82.2 10.2 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 EGB07010.1 - 2.5e-29 102.2 13.8 2.8e-29 102.0 13.8 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Neurensin PF14927.6 EGB07010.1 - 0.098 12.4 2.3 0.84 9.3 0.2 2.1 2 0 0 2 2 2 0 Neurensin DUF3040 PF11239.8 EGB07010.1 - 2.6 8.4 5.2 7.6 6.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) IGPS PF00218.21 EGB07011.1 - 6.5e-65 218.8 0.0 7.3e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase UQ_con PF00179.26 EGB07012.1 - 2.7e-15 56.3 0.0 3.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Proteasome PF00227.26 EGB07013.1 - 9.5e-47 158.9 0.3 1.2e-46 158.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB07013.1 - 1.1e-13 50.5 0.0 1.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature VWA_CoxE PF05762.14 EGB07015.1 - 0.041 13.3 0.1 0.48 9.8 0.1 2.1 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VWA PF00092.28 EGB07015.1 - 0.082 13.1 0.0 12 6.2 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain PfkB PF00294.24 EGB07016.1 - 1.3e-58 198.7 10.9 1.6e-58 198.4 10.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGB07016.1 - 5e-09 35.9 0.2 9.1e-09 35.0 0.2 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Rib_5-P_isom_A PF06026.14 EGB07017.1 - 4.4e-36 124.1 0.0 5.3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Glyco_transf_24 PF18404.1 EGB07018.1 - 1.1e-132 441.4 0.3 1.3e-132 441.2 0.3 1.0 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_8 PF01501.20 EGB07018.1 - 2.9e-09 36.9 0.1 3.9e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Myb_DNA-binding PF00249.31 EGB07019.1 - 6.5e-12 45.5 0.4 2.3e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB07019.1 - 6.9e-10 39.0 0.2 3e-06 27.4 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain TetR_C_12 PF16914.5 EGB07019.1 - 0.14 12.3 0.5 0.29 11.3 0.3 1.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal Pkinase PF00069.25 EGB07020.1 - 7.7e-72 241.8 0.0 8.7e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07020.1 - 3.3e-41 141.3 0.0 3.7e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB07020.1 - 1.1e-07 31.5 0.0 5e-07 29.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGB07020.1 - 0.00053 19.4 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB07020.1 - 0.01 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EGB07020.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGB07020.1 - 0.17 11.8 0.0 0.58 10.0 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF563 PF04577.14 EGB07021.1 - 2.2e-12 47.6 0.3 1.4e-11 44.9 0.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF563) DUF1325 PF07039.11 EGB07022.1 - 1.6e-07 31.4 0.0 5.1e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 SGF29 tudor-like domain LBR_tudor PF09465.10 EGB07022.1 - 0.00032 20.4 1.2 0.044 13.6 0.0 2.6 3 0 0 3 3 3 2 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 EGB07022.1 - 0.00082 19.0 8.3 0.12 12.1 1.5 2.6 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 EGB07022.1 - 0.011 15.6 0.2 0.68 9.8 0.1 2.6 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EGB07022.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 EGB07022.1 - 0.043 13.8 0.3 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor Tudor_2 PF18104.1 EGB07022.1 - 0.82 9.4 4.1 0.28 10.9 0.1 2.3 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain HSF_DNA-bind PF00447.17 EGB07023.1 - 8.3e-25 87.2 0.0 9.3e-25 87.1 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding RAG1_imp_bd PF12560.8 EGB07023.1 - 0.029 13.9 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 RAG1 importin binding Trehalose_PPase PF02358.16 EGB07025.1 - 1.2e-47 162.0 0.0 3.5e-40 137.6 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Kinesin PF00225.23 EGB07026.1 - 1.2e-118 395.8 0.0 2.3e-118 394.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB07026.1 - 1.2e-24 86.9 0.0 2.9e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF812 PF05667.11 EGB07026.1 - 0.00013 21.0 17.6 0.0002 20.4 17.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Kinesin_assoc PF16183.5 EGB07026.1 - 0.061 13.5 0.0 0.061 13.5 0.0 3.0 3 0 0 3 3 3 0 Kinesin-associated DUF4363 PF14276.6 EGB07026.1 - 0.83 9.8 5.7 3.6 7.7 5.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DLP_helical PF18709.1 EGB07026.1 - 1.8 7.7 22.5 0.13 11.4 8.6 2.3 1 1 1 2 2 2 0 Dynamin-like helical domain Fib_alpha PF08702.10 EGB07026.1 - 5.4 7.2 9.4 2 8.6 5.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Proteasome PF00227.26 EGB07027.1 - 1.1e-29 103.3 0.0 1.2e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CoA_binding PF02629.19 EGB07028.1 - 5.8e-30 103.8 0.4 5.8e-30 103.8 0.4 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGB07028.1 - 1.3e-25 90.0 0.1 2.1e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGB07028.1 - 1.6e-09 37.7 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGB07028.1 - 5.2e-05 23.7 0.1 0.00021 21.8 0.0 2.0 3 0 0 3 3 3 1 CoA binding domain His_Phos_1 PF00300.22 EGB07029.1 - 1.7e-30 106.1 0.7 1.6e-26 93.2 1.5 2.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) PX PF00787.24 EGB07029.1 - 2.1e-08 34.1 0.0 4.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PX domain Glyco_transf_90 PF05686.12 EGB07029.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 Thioredoxin PF00085.20 EGB07031.1 - 2.9e-37 126.8 0.0 5e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 EGB07031.1 - 2.2e-07 31.0 0.0 0.0029 17.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EGB07031.1 - 1.3e-06 28.0 0.0 0.0062 15.9 0.0 2.1 1 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGB07031.1 - 4.1e-06 27.2 0.1 0.17 12.4 0.0 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGB07031.1 - 1.9e-05 24.9 0.0 0.061 13.7 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_4 PF13462.6 EGB07031.1 - 0.00032 20.9 0.1 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 EGB07031.1 - 0.0031 17.4 0.0 0.063 13.2 0.0 2.5 2 1 1 3 3 3 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGB07031.1 - 0.0043 16.8 0.1 1.2 8.9 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 EGB07031.1 - 0.05 13.8 0.1 13 6.1 0.0 3.0 3 1 0 3 3 3 0 Glutaredoxin Thioredoxin_6 PF13848.6 EGB07031.1 - 0.26 11.2 0.0 26 4.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain EMP70 PF02990.16 EGB07032.1 - 6.1e-181 602.6 0.0 8e-181 602.2 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Orai-1 PF07856.12 EGB07032.1 - 0.00012 21.8 3.1 0.01 15.5 3.0 2.7 1 1 0 1 1 1 1 Mediator of CRAC channel activity PKD_channel PF08016.12 EGB07033.1 - 6.7e-19 67.9 15.0 1.3e-16 60.3 11.4 2.8 2 1 0 2 2 2 1 Polycystin cation channel MAM PF00629.23 EGB07033.1 - 1.1e-13 51.4 0.0 1.9e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Ion_trans PF00520.31 EGB07033.1 - 8.1e-09 35.1 6.3 8.1e-09 35.1 6.3 1.5 2 0 0 2 2 2 1 Ion transport protein Notch PF00066.17 EGB07033.1 - 0.0062 17.0 3.5 0.0062 17.0 3.5 3.2 3 0 0 3 3 3 1 LNR domain VCBS PF13517.6 EGB07034.1 - 8.8e-121 394.6 254.2 1.5e-09 38.3 8.1 26.1 7 5 18 25 25 25 24 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella REJ PF02010.15 EGB07034.1 - 2.6e-32 112.2 0.0 4.5e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 REJ domain Laminin_G_3 PF13385.6 EGB07034.1 - 2.1e-16 60.4 3.9 2.1e-16 60.4 3.9 9.8 7 3 5 14 14 14 1 Concanavalin A-like lectin/glucanases superfamily AbfS_sensor PF18225.1 EGB07034.1 - 9.6e-08 31.8 0.0 1.1e+02 2.9 0.0 11.3 13 0 0 13 13 13 0 Sensor histidine kinase (AbfS) sensor domain GPS PF01825.21 EGB07034.1 - 9.8e-07 29.2 7.1 3.8e-06 27.3 7.1 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF4330 PF14221.6 EGB07034.1 - 0.13 12.5 0.1 37 4.5 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4330) DUF1510 PF07423.11 EGB07034.1 - 2.1 8.6 24.3 45 4.3 0.0 11.2 14 0 0 14 14 14 0 Domain of unknown function (DUF1510) PP2C PF00481.21 EGB07035.1 - 5.6e-42 144.2 0.1 7.9e-42 143.7 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 EGB07035.1 - 1.6e-20 73.6 0.0 2.6e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07035.1 - 9.7e-06 25.0 0.0 2.9e-05 23.5 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGB07035.1 - 0.025 13.9 0.0 0.077 12.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIIE PF07228.12 EGB07035.1 - 0.036 14.0 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Sulfotransfer_3 PF13469.6 EGB07036.1 - 1.2e-08 35.6 1.2 4.5e-06 27.2 0.3 3.6 3 1 0 3 3 3 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB07036.1 - 0.0021 17.6 0.0 0.72 9.3 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Pkinase PF00069.25 EGB07037.1 - 2.6e-36 125.3 0.0 3.5e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07037.1 - 5.9e-16 58.5 0.0 2.1e-15 56.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB07037.1 - 5.1e-06 26.6 0.0 9.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB07037.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGB07037.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EGB07037.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EGB07037.1 - 0.18 11.1 0.2 0.81 8.9 0.2 1.9 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGB07037.1 - 0.21 10.4 0.1 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase EMP70 PF02990.16 EGB07038.1 - 6.1e-48 163.8 8.0 6.1e-48 163.8 8.0 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 Kinesin PF00225.23 EGB07040.1 - 1.1e-35 123.1 0.0 6.1e-34 117.4 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB07040.1 - 3.9e-05 23.6 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 EGB07040.1 - 4.2e-05 23.9 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB07040.1 - 0.00067 20.1 0.2 0.002 18.5 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGB07040.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 EGB07040.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGB07040.1 - 0.04 13.2 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 EGB07040.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaJ PF00226.31 EGB07041.1 - 6.7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_26 PF02156.15 EGB07042.1 - 0.009 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Castor_Poll_mid PF06241.12 EGB07043.1 - 0.00042 20.2 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel Ion_trans PF00520.31 EGB07043.1 - 0.0033 16.7 0.1 0.0056 15.9 0.1 1.3 1 0 0 1 1 1 1 Ion transport protein PRA1 PF03208.19 EGB07043.1 - 0.036 13.7 0.3 0.092 12.4 0.3 1.6 1 1 0 1 1 1 0 PRA1 family protein TrkA_C PF02080.21 EGB07043.1 - 0.082 12.8 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-C domain Pro_isomerase PF00160.21 EGB07044.1 - 1.1e-48 165.5 0.1 1.8e-48 164.8 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 EGB07044.1 - 5.5e-11 41.8 0.0 6e-08 32.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07044.1 - 1.5e-08 34.1 4.7 5e-05 23.1 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07044.1 - 6e-08 32.3 0.1 0.00023 21.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB07044.1 - 1.2e-05 25.8 4.3 0.00029 21.4 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB07044.1 - 3.4e-05 24.3 3.5 0.00038 21.0 0.2 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB07044.1 - 5.3e-05 22.8 0.6 0.091 12.5 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 EGB07044.1 - 0.00019 21.5 0.1 0.00041 20.5 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07044.1 - 0.00026 21.4 1.1 0.0062 17.0 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB07044.1 - 0.0014 19.1 3.1 0.17 12.6 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB07044.1 - 0.032 14.6 0.1 1.5 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat FKBP_N_2 PF18023.1 EGB07044.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 BDBT FKBP like N-terminal TPR_12 PF13424.6 EGB07044.1 - 0.094 13.0 0.3 1.3 9.4 0.0 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 EGB07044.1 - 1.9 8.9 9.7 20 5.6 0.3 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ribosomal_L7Ae PF01248.26 EGB07045.1 - 1.5e-22 79.1 0.2 1.8e-22 78.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SET PF00856.28 EGB07046.1 - 7.3e-08 33.0 0.0 1.3e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 SET domain DUF2183 PF09949.9 EGB07046.1 - 0.22 11.9 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) FAD_binding_1 PF00667.20 EGB07047.1 - 4.6e-25 88.5 0.0 6.4e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGB07047.1 - 2.3e-17 63.5 0.0 4.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGB07047.1 - 3.3e-09 37.3 0.0 5.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Malic_M PF03949.15 EGB07048.1 - 2.6e-86 289.1 0.8 3.3e-86 288.7 0.8 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGB07048.1 - 5.5e-66 221.8 0.0 7.3e-66 221.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_28 PF00295.17 EGB07049.1 - 8e-08 31.7 0.2 1.6e-07 30.7 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EGB07049.1 - 9.1e-06 25.7 0.1 0.00027 20.9 0.0 2.5 2 1 0 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 EGB07049.1 - 0.0096 15.8 0.2 0.21 11.4 0.0 2.6 2 1 0 2 2 2 1 Right handed beta helix region Coat_X PF07552.11 EGB07049.1 - 0.014 15.2 0.2 8.7 6.3 0.0 3.3 3 0 0 3 3 3 0 Spore Coat Protein X and V domain End_N_terminal PF12218.8 EGB07049.1 - 0.033 13.9 0.3 0.12 12.1 0.3 2.0 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase START PF01852.19 EGB07051.1 - 1e-08 34.8 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 START domain WW PF00397.26 EGB07051.1 - 6.3e-08 32.6 1.0 1.3e-07 31.5 1.0 1.6 1 0 0 1 1 1 1 WW domain PHD PF00628.29 EGB07051.1 - 0.0027 17.6 18.0 0.0072 16.2 5.8 2.6 2 0 0 2 2 2 2 PHD-finger ZF-HD_dimer PF04770.12 EGB07051.1 - 1.4 9.3 9.3 0.36 11.2 3.0 3.2 3 0 0 3 3 3 0 ZF-HD protein dimerisation region cNMP_binding PF00027.29 EGB07052.1 - 2.4e-11 43.5 0.0 5.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Glyco_hydro_92 PF07971.12 EGB07053.1 - 1e-100 337.9 0.0 1.2e-100 337.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGB07053.1 - 3.8e-14 53.2 1.2 6.1e-14 52.5 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain LtrA PF06772.11 EGB07054.1 - 5.8e-26 91.6 21.1 1e-25 90.7 19.4 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Abhydrolase_3 PF07859.13 EGB07054.1 - 5.1e-13 49.4 5.3 9.1e-13 48.5 5.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGB07054.1 - 5.8e-11 41.9 0.7 2.6e-10 39.8 0.7 1.8 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 EGB07054.1 - 0.0011 18.0 0.0 0.0037 16.2 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF3920 PF13058.6 EGB07054.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Hydrolase_like PF13242.6 EGB07056.1 - 0.00058 19.9 0.1 0.001 19.1 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGB07056.1 - 0.00063 19.9 0.0 0.00079 19.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB07056.1 - 0.047 14.0 0.0 0.31 11.3 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 EGB07056.1 - 0.049 13.4 0.0 0.19 11.5 0.0 2.0 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 EGB07056.1 - 0.076 12.9 0.1 0.31 10.9 0.0 2.1 2 1 0 2 2 2 0 Acid Phosphatase Rota_NS35 PF02509.14 EGB07056.1 - 0.14 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 SIR2_2 PF13289.6 EGB07056.1 - 0.17 12.0 0.0 7.3 6.7 0.0 2.2 2 0 0 2 2 2 0 SIR2-like domain PP2C PF00481.21 EGB07057.1 - 5.8e-32 111.3 0.0 6.9e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB07057.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF3659 PF12396.8 EGB07057.1 - 0.096 12.6 0.1 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3659) DUF1126 PF06565.12 EGB07058.1 - 6.2e-98 321.7 0.0 1.8e-34 117.7 0.3 3.1 3 0 0 3 3 3 3 DUF1126 PH-like domain Agglutinin_C PF18021.1 EGB07058.1 - 0.0061 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Agglutinin C-terminal AFG1_ATPase PF03969.16 EGB07059.1 - 7.2e-75 252.1 1.1 3.9e-72 243.1 0.7 2.3 2 1 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.6 EGB07059.1 - 0.002 18.4 0.2 0.013 15.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain Cation_efflux PF01545.21 EGB07061.1 - 3.4e-35 121.6 0.4 4.3e-35 121.3 0.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGB07061.1 - 8.1e-17 61.1 0.0 1e-08 35.1 0.1 2.4 2 0 0 2 2 2 2 Dimerisation domain of Zinc Transporter Rhomboid PF01694.22 EGB07062.1 - 3.3e-18 66.1 1.4 3.4e-18 66.1 1.4 1.0 1 0 0 1 1 1 1 Rhomboid family OB_NTP_bind PF07717.16 EGB07063.1 - 1.1e-19 70.6 0.1 2.2e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGB07063.1 - 2e-13 50.6 0.0 4.9e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EGB07063.1 - 2.4e-13 50.3 1.6 3.4e-13 49.8 0.0 2.1 2 1 0 2 2 2 1 Helicase associated domain (HA2) AAA_22 PF13401.6 EGB07063.1 - 3.1e-05 24.2 0.0 0.00011 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGB07063.1 - 0.00025 20.9 0.2 0.00099 18.9 0.2 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EGB07063.1 - 0.0026 16.9 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EGB07063.1 - 0.0041 16.9 0.5 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGB07063.1 - 0.011 16.0 0.0 0.037 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGB07063.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 EGB07063.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Bac_small_YrzI PF09501.10 EGB07064.1 - 0.59 10.3 1.8 3.2 7.9 1.8 2.4 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Pkinase PF00069.25 EGB07065.1 - 1.2e-63 215.0 0.0 1.4e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07065.1 - 4.4e-33 114.7 0.0 5.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB07065.1 - 0.0089 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB07065.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RCC1 PF00415.18 EGB07066.1 - 5.2e-71 235.1 37.2 1.9e-15 57.2 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB07066.1 - 2.1e-20 72.0 55.7 2.8e-07 30.2 3.1 9.2 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 EGB07066.1 - 0.18 12.2 0.0 7.7 7.0 0.0 2.3 2 0 0 2 2 2 0 SUKH-3 immunity protein EF-hand_1 PF00036.32 EGB07067.1 - 8.1e-15 53.2 1.5 1.2e-06 27.7 0.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB07067.1 - 1.1e-13 51.4 2.2 1.2e-13 51.2 2.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB07067.1 - 1.2e-12 46.7 3.1 8e-07 28.5 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB07067.1 - 1.1e-09 37.3 2.1 0.00084 18.7 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EGB07067.1 - 1.1e-08 35.0 1.3 0.0011 18.8 0.5 2.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 EGB07067.1 - 2.7e-08 33.5 5.6 1.8e-06 27.7 1.4 1.9 1 1 1 2 2 2 2 EF-hand domain pair NFACT-R_1 PF05670.13 EGB07068.1 - 5.5e-38 130.0 0.0 7.3e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF2828 PF11443.8 EGB07069.1 - 1.3e-28 99.5 0.0 1.5e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 EGB07069.1 - 6.4e-05 22.5 0.0 9.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EGB07069.1 - 0.0008 20.0 0.0 0.0012 19.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGB07069.1 - 0.0012 18.8 0.0 0.0015 18.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.8 EGB07069.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain SNF2_N PF00176.23 EGB07070.1 - 2.3e-36 125.3 0.0 7.1e-36 123.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB07070.1 - 1.3e-17 64.1 0.0 2.1e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB07070.1 - 0.00044 20.3 0.0 0.00087 19.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_trans_A_1 PF09318.10 EGB07070.1 - 0.0034 17.1 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 1 domain A DEAD PF00270.29 EGB07070.1 - 0.035 13.9 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase DEAD_2 PF06733.15 EGB07070.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 AAA_22 PF13401.6 EGB07070.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain UTP25 PF06862.12 EGB07070.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GHL15 PF14885.6 EGB07071.1 - 4.7e-19 69.4 0.0 7.3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 15 ABC_tran PF00005.27 EGB07072.1 - 1.5e-23 83.8 0.0 1.9e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB07072.1 - 2.8e-06 27.4 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB07072.1 - 0.00051 20.0 0.5 0.00096 19.1 0.5 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGB07072.1 - 0.00052 20.4 0.3 0.0015 19.0 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGB07072.1 - 0.0015 18.1 0.4 1.1 8.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGB07072.1 - 0.0026 18.1 0.1 0.0081 16.4 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB07072.1 - 0.0053 17.3 0.2 0.011 16.3 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB07072.1 - 0.0061 16.3 0.4 0.012 15.4 0.4 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EGB07072.1 - 0.0073 16.5 0.1 0.013 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB07072.1 - 0.013 15.1 4.3 0.05 13.2 4.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB07072.1 - 0.015 15.8 0.2 0.023 15.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB07072.1 - 0.015 15.5 0.8 0.029 14.6 0.8 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB07072.1 - 0.018 14.8 3.0 0.021 14.6 0.8 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGB07072.1 - 0.027 14.9 0.2 0.2 12.0 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EGB07072.1 - 0.039 13.5 0.2 0.059 12.9 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EGB07072.1 - 0.095 12.4 0.3 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EGB07072.1 - 0.12 12.6 0.1 0.53 10.5 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Cytidylate_kin PF02224.18 EGB07072.1 - 0.15 11.8 0.6 0.23 11.2 0.2 1.4 2 0 0 2 2 2 0 Cytidylate kinase NACHT PF05729.12 EGB07072.1 - 0.2 11.6 0.3 0.34 10.8 0.3 1.3 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EGB07072.1 - 0.24 11.4 0.2 0.51 10.4 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glyco_transf_11 PF01531.16 EGB07073.1 - 6.9e-05 22.2 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 11 ADH_zinc_N PF00107.26 EGB07074.1 - 2.6e-15 56.5 3.7 7.8e-15 55.0 3.7 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGB07074.1 - 2.3e-13 51.3 1.4 5.8e-13 50.0 0.3 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB07074.1 - 8.8e-09 35.2 0.5 6.6e-08 32.4 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DUF501 PF04417.12 EGB07075.1 - 7.1e-27 93.9 0.0 7.1e-27 93.9 0.0 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF501) U-box PF04564.15 EGB07077.1 - 1.2e-17 63.8 0.0 2.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB07077.1 - 0.0019 17.9 0.1 0.004 16.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EGB07077.1 - 0.035 14.2 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Fez1 PF06818.15 EGB07077.1 - 0.14 12.6 4.2 0.31 11.5 4.2 1.6 1 0 0 1 1 1 0 Fez1 CENP-F_leu_zip PF10473.9 EGB07077.1 - 0.19 11.7 1.3 3.5 7.6 0.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EGB07077.1 - 0.29 10.5 1.0 0.5 9.7 1.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGB07077.1 - 0.77 8.6 2.3 1.1 8.0 1.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 EGB07077.1 - 1.2 8.2 3.8 1.8 7.6 3.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 EGB07077.1 - 1.8 8.6 10.7 5.7 7.0 10.3 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EGB07077.1 - 6.7 7.2 9.0 4.1 7.9 2.6 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3584 PF12128.8 EGB07077.1 - 8 3.8 13.4 11 3.3 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ABC1 PF03109.16 EGB07078.1 - 1.8e-18 66.8 0.0 3.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB07078.1 - 0.00045 20.2 0.2 0.0045 16.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGB07078.1 - 0.048 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain PH_4 PF15404.6 EGB07078.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF5529 PF17669.1 EGB07079.1 - 0.035 14.1 1.5 0.087 12.9 1.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5529) MatE PF01554.18 EGB07080.1 - 5.7e-24 84.6 30.0 7.2e-14 51.8 5.9 3.6 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGB07080.1 - 4.9e-05 23.4 4.3 4.9e-05 23.4 4.3 3.7 2 2 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain RRM_1 PF00076.22 EGB07081.1 - 1.1e-15 57.2 0.0 1.2e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.31 EGB07082.1 - 8.7e-15 54.7 2.2 7.5e-09 35.6 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB07082.1 - 3.7e-12 46.3 0.0 2.6e-11 43.6 0.0 1.9 1 1 1 2 2 2 1 Myb-like DNA-binding domain SpoU_methylase PF00588.19 EGB07083.1 - 1e-28 100.3 0.0 1.2e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family GFRP PF06399.13 EGB07083.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Sugar_tr PF00083.24 EGB07084.1 - 7.7e-90 301.9 17.6 9.2e-90 301.7 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB07084.1 - 2.3e-28 99.1 50.3 4.5e-27 94.9 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4574 PF15141.6 EGB07084.1 - 2.7 8.0 6.2 13 5.8 0.1 3.5 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 FA_desaturase PF00487.24 EGB07085.1 - 2.1e-32 113.0 16.4 2.1e-32 113.0 16.4 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGB07085.1 - 9.7e-15 54.5 0.0 2.1e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PDEase_I PF00233.19 EGB07086.1 - 3.3e-69 233.2 0.0 3.8e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PKcGMP_CC PF16808.5 EGB07087.1 - 0.017 15.0 12.7 1.8 8.5 0.7 5.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Trypsin_2 PF13365.6 EGB07088.1 - 1.5e-20 74.7 8.6 8.3e-17 62.5 0.1 3.7 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_1 PF12812.7 EGB07088.1 - 1.5e-18 66.5 0.0 5.4e-09 35.9 0.0 3.5 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.6 EGB07088.1 - 1.4e-12 47.7 0.0 0.072 13.4 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 EGB07088.1 - 5.7e-12 45.3 0.3 0.002 18.0 0.0 4.6 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 EGB07088.1 - 1.2e-05 25.6 0.0 0.13 12.6 0.0 3.6 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 EGB07088.1 - 0.011 15.7 0.1 0.55 10.2 0.0 3.3 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 EGB07088.1 - 0.011 14.4 0.2 0.019 13.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S3 PF00944.19 EGB07088.1 - 0.027 14.3 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Alphavirus core protein Trypsin PF00089.26 EGB07088.1 - 0.077 12.8 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Trypsin Peptidase_S7 PF00949.21 EGB07088.1 - 0.096 12.5 1.2 0.2 11.5 1.2 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease TauE PF01925.19 EGB07089.1 - 4.5e-11 42.8 24.4 4.5e-11 42.8 24.4 2.8 2 1 0 2 2 2 1 Sulfite exporter TauE/SafE fn2 PF00040.19 EGB07089.1 - 7.2e-10 39.0 3.8 1.4e-09 38.1 3.8 1.5 1 0 0 1 1 1 1 Fibronectin type II domain Sel1 PF08238.12 EGB07089.1 - 3.1e-06 27.7 1.1 0.0067 17.1 0.1 3.0 2 0 0 2 2 2 2 Sel1 repeat AT_hook PF02178.19 EGB07089.1 - 0.026 14.4 2.6 0.064 13.1 2.6 1.7 1 0 0 1 1 1 0 AT hook motif VCBS PF13517.6 EGB07090.1 - 3.8e-30 104.3 77.3 1.8e-09 38.1 6.9 7.5 4 3 4 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Laminin_G_3 PF13385.6 EGB07090.1 - 8e-12 45.6 1.4 2.4e-10 40.8 0.1 2.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily FG-GAP PF01839.23 EGB07090.1 - 0.066 13.4 51.2 0.032 14.4 3.4 7.2 7 0 0 7 7 7 0 FG-GAP repeat PPR_long PF17177.4 EGB07090.1 - 0.19 11.1 0.2 0.35 10.2 0.2 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP TspO_MBR PF03073.15 EGB07091.1 - 1.5e-28 99.5 14.4 1.7e-28 99.4 14.4 1.0 1 0 0 1 1 1 1 TspO/MBR family WD40 PF00400.32 EGB07093.1 - 4.1e-56 185.7 32.9 2.2e-09 37.8 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB07093.1 - 6.5e-20 71.2 5.7 0.016 15.5 0.2 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB07093.1 - 2.6e-11 43.8 1.8 0.0019 18.1 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGB07093.1 - 3e-10 39.6 11.9 0.42 9.5 0.3 6.6 1 1 6 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGB07093.1 - 7.1e-06 25.8 1.8 2.7 8.1 0.0 5.2 6 0 0 6 6 5 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EGB07093.1 - 2.4e-05 23.8 0.1 1.9 7.7 0.0 3.8 1 1 2 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 EGB07093.1 - 0.00041 19.0 0.8 0.58 8.6 0.1 3.6 1 1 3 4 4 4 2 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 EGB07093.1 - 0.0042 16.0 4.4 2 7.2 0.0 3.8 1 1 3 4 4 4 2 Partner and localizer of BRCA2 WD40 domain BRCT PF00533.26 EGB07093.1 - 0.0091 16.4 0.9 0.032 14.6 0.0 2.3 3 0 0 3 3 2 1 BRCA1 C Terminus (BRCT) domain DUF4875 PF16175.5 EGB07093.1 - 0.035 14.2 4.8 2.4 8.3 0.2 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4875) B_lectin PF01453.24 EGB07093.1 - 0.052 14.1 1.8 0.35 11.4 0.0 2.5 3 1 0 3 3 2 0 D-mannose binding lectin Toxin_10 PF05431.11 EGB07093.1 - 0.11 11.9 1.6 0.17 11.3 0.6 1.8 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 DUF5570 PF17731.1 EGB07093.1 - 0.15 12.1 5.8 2.9 8.0 0.0 3.7 1 1 4 5 5 5 0 Family of unknown function (DUF5570) Frtz PF11768.8 EGB07093.1 - 0.19 10.0 0.8 12 4.0 0.0 3.2 2 1 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Glyoxal_oxid_N PF07250.11 EGB07093.1 - 0.3 10.2 6.7 1.4 8.1 0.4 2.9 3 1 1 4 4 4 0 Glyoxal oxidase N-terminus TGBp3 PF02495.17 EGB07093.1 - 0.31 10.7 5.4 9.9 5.9 0.0 4.2 5 0 0 5 5 5 0 Triple gene block 3 RCC1_2 PF13540.6 EGB07093.1 - 0.93 9.4 5.0 8.4 6.3 0.1 3.6 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S21e PF01249.18 EGB07094.1 - 9.9e-35 118.5 0.0 1.1e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e TFIIA PF03153.13 EGB07095.1 - 1.6 8.6 10.4 2.7 7.9 10.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pro_isomerase PF00160.21 EGB07096.1 - 4.7e-43 147.2 0.1 5.4e-43 147.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sel1 PF08238.12 EGB07097.1 - 9e-18 64.3 4.5 4.5e-06 27.2 0.2 3.0 3 0 0 3 3 3 3 Sel1 repeat TPR_2 PF07719.17 EGB07097.1 - 0.7 10.2 4.6 3.6 7.9 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat KIX_2 PF16987.5 EGB07098.1 - 0.21 11.6 0.1 0.35 10.9 0.1 1.3 1 0 0 1 1 1 0 KIX domain zf-CCCH_2 PF14608.6 EGB07099.1 - 0.0081 16.6 1.2 0.0081 16.6 1.2 3.4 4 0 0 4 4 4 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGB07099.1 - 0.044 14.0 0.2 0.1 12.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger containing family Nfu_N PF08712.11 EGB07101.1 - 1.5e-27 95.5 0.0 2.8e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EGB07101.1 - 4.7e-25 87.5 0.1 7e-25 87.0 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain PGI PF00342.19 EGB07101.1 - 0.16 10.5 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase PhyH PF05721.13 EGB07102.1 - 2.2e-16 60.8 0.0 3.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DEC-1_N PF04625.13 EGB07102.1 - 0.27 10.2 1.0 0.47 9.4 1.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-MYND PF01753.18 EGB07103.1 - 2e-09 37.3 13.7 3.4e-09 36.6 13.7 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGB07103.1 - 0.27 11.6 8.0 0.51 10.7 8.0 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Nuc_sug_transp PF04142.15 EGB07104.1 - 1.1e-90 304.0 8.1 6.6e-90 301.5 8.1 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB07104.1 - 1.6e-06 28.3 1.1 1.6e-06 28.3 1.1 2.8 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.6 EGB07104.1 - 0.00029 20.5 0.5 0.00071 19.2 0.1 1.7 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 EGB07104.1 - 0.013 14.8 1.5 0.017 14.4 1.5 1.3 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport Chloroa_b-bind PF00504.21 EGB07105.1 - 5.5e-34 118.0 0.2 8.1e-34 117.5 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein 2-Hacid_dh_C PF02826.19 EGB07106.1 - 1.9e-52 177.2 0.0 2.6e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGB07106.1 - 3e-12 46.3 0.0 3.8e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DNase-RNase PF02577.14 EGB07106.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Bifunctional nuclease ANF_receptor PF01094.28 EGB07107.1 - 1.8e-28 99.7 0.1 2.6e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Ephrin_rec_like PF07699.13 EGB07107.1 - 0.00016 21.4 29.9 0.044 13.6 0.7 5.5 4 1 1 5 5 5 4 Putative ephrin-receptor like NCD3G PF07562.14 EGB07107.1 - 0.16 12.0 0.1 0.16 12.0 0.1 5.3 4 1 2 6 6 6 0 Nine Cysteines Domain of family 3 GPCR adh_short_C2 PF13561.6 EGB07108.1 - 7.8e-52 176.1 9.4 1.1e-51 175.7 9.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB07108.1 - 2.6e-46 157.5 4.1 3.6e-46 157.1 4.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB07108.1 - 2.3e-12 47.2 2.6 7e-12 45.6 2.6 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB07108.1 - 7.7e-06 25.5 1.5 1.6e-05 24.5 1.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGB07108.1 - 0.099 11.8 0.1 0.15 11.2 0.1 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGB07108.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2710 PF10921.8 EGB07108.1 - 0.19 12.1 1.0 2 8.9 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2710) DUF2703 PF10865.8 EGB07108.1 - 0.21 11.8 0.0 0.55 10.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) 3HCDH_N PF02737.18 EGB07108.1 - 0.25 11.2 1.8 0.52 10.2 1.8 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TraA PF05513.11 EGB07108.1 - 2.2 8.6 5.0 2.9 8.2 0.6 2.4 2 0 0 2 2 2 0 TraA Ribosomal_L31e PF01198.19 EGB07109.1 - 1.1e-42 144.1 1.5 1.5e-42 143.7 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 EGB07109.1 - 0.042 13.9 0.1 0.052 13.6 0.1 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Pkinase PF00069.25 EGB07111.1 - 2e-31 109.3 0.0 2.9e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07111.1 - 2.5e-30 105.6 0.0 3.3e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB07111.1 - 5.2e-05 23.3 0.8 0.00043 20.3 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family GST_C_2 PF13410.6 EGB07112.1 - 5e-11 42.5 1.9 3.2e-10 39.9 1.3 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGB07112.1 - 2.3e-06 27.7 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB07112.1 - 8.9e-05 22.6 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGB07112.1 - 0.0016 19.0 0.0 0.0039 17.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EspB PF05802.11 EGB07112.1 - 0.91 9.5 2.8 1.3 9.0 2.8 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein WW PF00397.26 EGB07113.1 - 0.0003 20.8 1.2 0.00064 19.8 1.2 1.5 1 0 0 1 1 1 1 WW domain TolA_bind_tri PF16331.5 EGB07113.1 - 0.0029 17.6 0.1 1.8 8.7 0.0 3.2 2 0 0 2 2 2 2 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 EGB07113.1 - 0.092 12.8 1.6 2 8.4 0.0 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2807 PF10988.8 EGB07113.1 - 5.8 6.7 46.0 3.2 7.5 1.7 5.1 1 1 4 5 5 5 0 Putative auto-transporter adhesin, head GIN domain UDG PF03167.19 EGB07114.1 - 1.3e-19 70.7 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SecY PF00344.20 EGB07115.1 - 1.3e-66 225.0 4.1 1.8e-66 224.5 4.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGB07115.1 - 2.9e-18 65.4 0.0 1.1e-17 63.6 0.0 2.1 1 0 0 1 1 1 1 Plug domain of Sec61p Fer2 PF00111.27 EGB07116.1 - 0.00041 20.2 2.2 0.00052 19.9 2.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 EGB07116.1 - 0.022 14.3 0.4 0.038 13.6 0.4 1.4 1 0 0 1 1 1 0 Magnetochrome domain IF4E PF01652.18 EGB07117.1 - 5.7e-48 162.7 0.0 6.3e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPR_12 PF13424.6 EGB07118.1 - 1.8e-23 82.6 37.2 2.7e-12 46.8 2.7 5.3 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGB07118.1 - 1.9e-11 43.4 29.6 1.9e-05 24.4 0.3 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGB07118.1 - 1.5e-06 27.8 16.2 0.12 12.5 0.3 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB07118.1 - 2.8e-05 23.7 13.1 0.54 10.2 0.3 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07118.1 - 0.00012 22.0 8.5 2 8.8 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 EGB07118.1 - 0.007 16.9 3.9 0.007 16.9 3.9 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07118.1 - 0.02 15.0 0.9 0.02 15.0 0.9 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EGB07118.1 - 0.022 14.7 1.9 0.6 10.0 0.0 3.1 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 EGB07118.1 - 1.5 9.0 14.0 2.1 8.6 0.9 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB07118.1 - 1.9 9.5 45.5 0.15 12.9 0.9 7.0 5 2 3 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB07118.1 - 5.8 7.5 9.3 4.2 8.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C1 PF00112.23 EGB07119.1 - 2.8e-72 243.3 3.2 3.9e-72 242.9 3.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB07119.1 - 1e-09 38.6 0.4 1.6e-09 38.1 0.4 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB07119.1 - 0.00083 18.2 1.2 0.17 10.6 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family ChuX_HutX PF06228.13 EGB07119.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX IF4E PF01652.18 EGB07120.1 - 5.7e-48 162.7 0.0 6.3e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.32 EGB07121.1 - 8.6e-20 70.7 3.6 0.00018 22.2 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB07121.1 - 9.1e-11 41.9 1.9 0.0038 17.5 0.1 4.5 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB07121.1 - 0.0015 18.4 0.0 0.0071 16.2 0.0 1.9 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGB07121.1 - 0.012 15.6 0.7 0.46 10.5 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SGL PF08450.12 EGB07121.1 - 0.061 12.9 0.1 1.1 8.8 0.0 2.6 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region GST_N_3 PF13417.6 EGB07122.1 - 9.4e-33 112.5 0.0 4.3e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB07122.1 - 5e-13 49.2 0.0 3.3e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EGB07122.1 - 7.7e-09 35.6 0.0 8.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Glutaredoxin GST_N PF02798.20 EGB07122.1 - 1.5e-08 34.9 0.0 6.2e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 EGB07122.1 - 0.021 15.1 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein PAP_fibrillin PF04755.12 EGB07123.1 - 4.2e-18 66.0 0.0 4e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 PAP_fibrillin VCBS PF13517.6 EGB07124.1 - 9.8e-144 468.1 313.3 3.1e-10 40.5 8.8 29.8 5 5 27 32 32 32 32 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella REJ PF02010.15 EGB07124.1 - 9.1e-24 84.1 0.0 2e-23 82.9 0.0 1.5 1 1 0 1 1 1 1 REJ domain AbfS_sensor PF18225.1 EGB07124.1 - 6.5e-08 32.4 0.0 5.2 7.1 0.0 10.1 12 0 0 12 12 12 1 Sensor histidine kinase (AbfS) sensor domain HTH_31 PF13560.6 EGB07124.1 - 8.3e-07 29.3 10.6 1.2e+02 3.1 0.0 13.5 16 0 0 16 16 16 0 Helix-turn-helix domain OapA PF04225.12 EGB07124.1 - 0.00052 20.1 0.1 1.7 8.8 0.0 6.4 8 0 0 8 8 8 1 Opacity-associated protein A LysM-like domain Lactonase PF10282.9 EGB07124.1 - 0.15 11.3 1.0 1.5 8.0 0.2 3.3 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller cNMP_binding PF00027.29 EGB07126.1 - 3.1e-12 46.4 0.1 6.9e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EF-hand_7 PF13499.6 EGB07127.1 - 5.2e-08 33.2 0.0 0.0039 17.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB07127.1 - 8.5e-08 31.9 0.2 0.0056 16.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB07127.1 - 1.1e-07 30.9 2.2 0.0022 17.4 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB07127.1 - 1.1e-07 31.1 2.2 0.0082 16.0 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB07127.1 - 3.5e-05 23.1 3.2 0.14 11.7 0.9 2.6 2 0 0 2 2 2 2 EF hand IQ PF00612.27 EGB07127.1 - 0.37 10.7 3.6 25 5.0 0.2 3.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif Snurportin1 PF11538.8 EGB07128.1 - 0.0082 16.3 7.8 0.019 15.1 7.8 1.6 1 0 0 1 1 1 1 Snurportin1 MyTH4 PF00784.17 EGB07130.1 - 2.7e-27 95.4 0.0 5.2e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 EGB07130.1 - 3.2e-19 69.5 0.0 7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 FERM central domain WW PF00397.26 EGB07130.1 - 3.3e-15 55.9 11.8 4.2e-08 33.1 2.7 2.7 2 0 0 2 2 2 2 WW domain RA PF00788.23 EGB07130.1 - 0.0022 18.6 0.0 0.011 16.3 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain FERM_C PF09380.10 EGB07130.1 - 0.0066 16.8 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PTB PF08416.13 EGB07130.1 - 0.0086 16.2 0.0 0.026 14.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotyrosine-binding domain FERM_N PF09379.10 EGB07130.1 - 0.051 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 FERM N-terminal domain Multi_Drug_Res PF00893.19 EGB07131.1 - 3.7e-16 59.6 3.8 4.8e-16 59.2 3.8 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EGB07131.1 - 0.0024 18.0 6.1 0.0026 17.9 6.1 1.0 1 0 0 1 1 1 1 EamA-like transporter family SLATT_6 PF18169.1 EGB07131.1 - 0.031 13.9 0.4 0.039 13.5 0.4 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 PRA1 PF03208.19 EGB07131.1 - 0.079 12.6 1.0 0.09 12.4 1.0 1.0 1 0 0 1 1 1 0 PRA1 family protein Gly_transf_sug PF04488.15 EGB07132.1 - 3.8e-08 33.8 0.0 8.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGB07132.1 - 0.19 11.1 0.1 0.28 10.5 0.1 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Asp PF00026.23 EGB07133.1 - 5e-48 164.2 0.0 3.1e-42 145.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGB07133.1 - 3.6e-06 27.3 2.5 0.00044 20.5 0.2 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGB07133.1 - 0.001 19.6 1.3 0.026 15.2 0.1 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGB07133.1 - 0.04 14.5 0.5 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PT PF04886.12 EGB07133.1 - 0.74 9.4 16.2 1.6 8.4 16.2 1.5 1 0 0 1 1 1 0 PT repeat NAD_binding_1 PF00175.21 EGB07134.1 - 2.1e-25 89.5 0.0 3.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGB07134.1 - 1.6e-15 57.2 0.0 2.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGB07134.1 - 9e-06 25.9 0.0 8.4e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Abhydrolase_2 PF02230.16 EGB07135.1 - 3.6e-06 26.9 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase TPR_1 PF00515.28 EGB07135.1 - 0.00018 21.2 0.5 0.0034 17.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07135.1 - 0.011 15.8 0.0 0.011 15.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_S9 PF00326.21 EGB07135.1 - 0.14 11.6 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family TPR_12 PF13424.6 EGB07135.1 - 0.15 12.3 9.4 0.23 11.8 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Lzipper-MIP1 PF14389.6 EGB07136.1 - 0.00021 21.5 0.7 0.0005 20.3 0.7 1.6 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Cnn_1N PF07989.11 EGB07136.1 - 0.0049 17.0 0.9 2.4 8.4 0.1 2.3 2 0 0 2 2 2 2 Centrosomin N-terminal motif 1 BST2 PF16716.5 EGB07136.1 - 0.0079 16.8 1.9 1.3 9.7 0.1 2.3 2 0 0 2 2 2 1 Bone marrow stromal antigen 2 betaPIX_CC PF16523.5 EGB07136.1 - 0.011 15.5 2.8 1.7 8.5 0.0 2.6 2 1 0 2 2 2 0 betaPIX coiled coil ZapB PF06005.12 EGB07136.1 - 0.017 15.5 2.6 3.6 8.1 0.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EGB07136.1 - 0.019 15.0 2.1 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor GrpE PF01025.19 EGB07136.1 - 0.02 14.6 2.4 0.95 9.1 0.0 2.1 2 0 0 2 2 2 0 GrpE Nup88 PF10168.9 EGB07136.1 - 0.02 12.7 2.2 0.76 7.5 0.2 2.0 1 1 1 2 2 2 0 Nuclear pore component YgaB PF14182.6 EGB07136.1 - 0.029 14.8 0.9 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 YgaB-like protein GIT_CC PF16559.5 EGB07136.1 - 0.037 13.9 1.6 0.82 9.6 0.4 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 EGB07136.1 - 0.038 14.3 0.8 1.8 9.0 0.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 EGB07136.1 - 0.054 13.5 4.0 0.78 9.8 0.0 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SPATA1_C PF15743.5 EGB07136.1 - 0.058 13.5 4.0 0.084 12.9 4.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Fez1 PF06818.15 EGB07136.1 - 0.066 13.7 5.1 0.4 11.1 0.6 2.1 1 1 1 2 2 2 0 Fez1 DUF1192 PF06698.11 EGB07136.1 - 0.087 12.9 2.7 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Nsp1_C PF05064.13 EGB07136.1 - 0.094 12.5 0.5 3.2 7.6 0.0 2.3 3 0 0 3 3 2 0 Nsp1-like C-terminal region Swi5 PF07061.11 EGB07136.1 - 0.1 12.7 2.0 8.7 6.5 0.1 2.3 2 0 0 2 2 2 0 Swi5 DUF5320 PF17253.2 EGB07136.1 - 0.14 13.2 0.8 11 7.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DivIC PF04977.15 EGB07136.1 - 0.15 11.9 3.8 4.8 7.0 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator Ax_dynein_light PF10211.9 EGB07136.1 - 0.17 11.8 5.1 0.58 10.1 0.8 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain bZIP_2 PF07716.15 EGB07136.1 - 0.18 11.9 4.1 0.88 9.7 0.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF4140 PF13600.6 EGB07136.1 - 0.24 11.9 6.0 0.91 10.0 0.2 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FAM184 PF15665.5 EGB07136.1 - 0.32 10.8 5.7 1 9.1 5.8 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B JAKMIP_CC3 PF16034.5 EGB07136.1 - 0.35 10.8 5.1 1.6 8.6 0.5 2.1 1 1 1 2 2 2 0 JAKMIP CC3 domain Peptidase_M64 PF09471.10 EGB07137.1 - 1.9e-17 63.7 0.0 3.1e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 IgA Peptidase M64 cobW PF02492.19 EGB07138.1 - 3.2e-48 163.7 2.4 4.1e-48 163.3 2.4 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB07138.1 - 3.8e-21 74.8 0.1 1.1e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGB07138.1 - 0.0002 21.3 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EGB07138.1 - 0.0033 16.5 0.4 0.0059 15.7 0.1 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 EGB07138.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EGB07138.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGB07138.1 - 0.038 14.3 0.0 0.067 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGB07138.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EGB07138.1 - 0.074 13.6 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EGB07138.1 - 0.076 13.6 0.1 0.19 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EGB07138.1 - 0.095 12.6 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 EGB07138.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB07138.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGB07138.1 - 0.15 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin 2-Hacid_dh_C PF02826.19 EGB07139.1 - 9e-34 116.4 0.0 3.2e-33 114.6 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGB07139.1 - 0.0006 20.0 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EGB07139.1 - 0.003 17.6 0.4 0.017 15.2 0.2 2.1 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 EGB07139.1 - 0.0065 15.9 0.3 0.022 14.1 0.3 1.7 2 0 0 2 2 2 1 ThiF family NAD_binding_7 PF13241.6 EGB07139.1 - 0.0078 16.6 0.6 0.017 15.5 0.2 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding DUF4440 PF14534.6 EGB07139.1 - 0.013 15.8 0.6 2.3 8.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) RcnB PF11776.8 EGB07139.1 - 0.017 15.2 1.0 0.065 13.3 1.0 2.1 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator ApbA PF02558.16 EGB07139.1 - 0.023 14.4 0.1 0.053 13.2 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 EGB07139.1 - 0.028 14.3 5.4 0.063 13.2 5.4 1.6 1 0 0 1 1 1 0 Rossmann-like domain AlaDh_PNT_C PF01262.21 EGB07139.1 - 0.04 13.2 0.7 0.068 12.5 0.7 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 EGB07139.1 - 0.099 12.1 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sel1 PF08238.12 EGB07140.1 - 1.2e-34 118.0 39.4 4.7e-08 33.5 0.5 6.0 6 0 0 6 6 6 6 Sel1 repeat TetR_C_7 PF14246.6 EGB07140.1 - 2.2 8.4 8.6 1.4 8.9 1.0 2.8 1 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Peptidase_S9 PF00326.21 EGB07141.1 - 1.4e-40 139.0 0.0 1.7e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGB07141.1 - 4.5e-09 36.3 0.1 3.8e-07 30.0 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB07141.1 - 4.4e-08 32.7 0.2 1.1e-05 24.8 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EGB07141.1 - 6.2e-08 32.5 0.0 9.1e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EGB07141.1 - 6.1e-05 23.7 13.1 0.00015 22.4 13.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EGB07141.1 - 9.2e-05 22.5 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EGB07141.1 - 0.00018 21.2 0.0 0.22 11.1 0.1 2.2 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 EGB07141.1 - 0.00038 19.4 0.1 0.00045 19.2 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGB07141.1 - 0.012 15.5 4.0 0.19 11.6 4.0 2.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EGB07141.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 EGB07141.1 - 0.033 13.4 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) AXE1 PF05448.12 EGB07141.1 - 0.056 12.1 0.0 1.7 7.3 0.0 2.3 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Peptidase_S28 PF05577.12 EGB07141.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Tannase PF07519.11 EGB07141.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Tannase and feruloyl esterase Peptidase_S10 PF00450.22 EGB07142.1 - 1.7e-42 146.3 0.0 1.8e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase BKACE PF05853.12 EGB07143.1 - 5.7e-97 324.3 0.0 6.5e-97 324.1 0.0 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme DUF4978 PF16349.5 EGB07143.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4978) 2OG-FeII_Oxy_2 PF13532.6 EGB07145.1 - 1.9e-12 47.8 0.0 2.7e-11 44.0 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 EGB07146.1 - 2.3e-42 144.8 0.0 5.5e-23 82.0 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB07146.1 - 1.3e-21 77.7 4.0 4.2e-06 26.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EGB07146.1 - 5.5e-19 68.0 1.3 3.7e-18 65.3 0.6 2.3 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGB07146.1 - 2.8e-13 49.8 0.0 0.00012 21.6 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB07146.1 - 1e-09 39.0 2.4 0.00011 22.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGB07146.1 - 2.7e-08 34.6 0.0 0.00062 20.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGB07146.1 - 3.5e-08 33.1 0.0 0.00028 20.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB07146.1 - 3.8e-07 30.2 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGB07146.1 - 9.7e-07 29.1 0.0 0.019 15.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 EGB07146.1 - 1.9e-06 27.9 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 EGB07146.1 - 4.1e-06 27.1 0.2 0.13 12.5 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 EGB07146.1 - 5.2e-06 26.4 0.0 0.009 15.8 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 EGB07146.1 - 6.8e-06 26.7 0.0 0.019 15.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGB07146.1 - 7.1e-06 26.2 0.0 0.14 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGB07146.1 - 1e-05 25.6 0.1 0.26 11.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EGB07146.1 - 1.2e-05 25.3 0.0 0.015 15.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGB07146.1 - 2.4e-05 24.2 0.1 0.3 10.8 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EGB07146.1 - 4.8e-05 23.2 0.2 0.16 11.7 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 EGB07146.1 - 5.4e-05 23.6 0.1 0.5 10.8 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGB07146.1 - 0.0001 22.4 0.0 0.27 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 EGB07146.1 - 0.00014 21.5 0.0 0.6 9.7 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EGB07146.1 - 0.00046 19.7 0.0 0.7 9.4 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 EGB07146.1 - 0.00066 20.0 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 EGB07146.1 - 0.0014 18.2 0.1 1 8.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EGB07146.1 - 0.002 17.7 0.2 0.19 11.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 EGB07146.1 - 0.0021 17.2 0.0 0.23 10.5 0.0 3.1 2 1 1 3 3 3 1 Type II/IV secretion system protein DUF3584 PF12128.8 EGB07146.1 - 0.0021 15.7 0.3 1.2 6.6 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) Roc PF08477.13 EGB07146.1 - 0.0026 18.0 0.0 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EGB07146.1 - 0.0028 17.6 0.1 1.6 8.6 0.0 2.4 2 0 0 2 2 2 1 NTPase SRP54 PF00448.22 EGB07146.1 - 0.0041 16.8 0.0 0.82 9.3 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EGB07146.1 - 0.0042 16.3 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 EGB07146.1 - 0.0047 16.9 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 EGB07146.1 - 0.0099 16.0 0.1 0.057 13.5 0.0 2.2 3 0 0 3 3 2 1 Helicase HerA, central domain DAP3 PF10236.9 EGB07146.1 - 0.011 14.9 0.1 2.1 7.4 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 MobB PF03205.14 EGB07146.1 - 0.011 15.6 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EGB07146.1 - 0.02 15.2 0.0 10 6.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 EGB07146.1 - 0.023 14.5 0.0 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 EGB07146.1 - 0.026 13.8 0.3 1.7 7.9 0.0 2.9 2 1 1 3 3 3 0 Zeta toxin AAA_17 PF13207.6 EGB07146.1 - 0.036 14.5 0.0 7.7 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGB07146.1 - 0.038 12.9 0.0 0.6 8.9 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.6 EGB07146.1 - 0.043 14.0 0.3 4.7 7.5 0.2 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EGB07146.1 - 0.05 13.5 0.0 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Dynamin_N PF00350.23 EGB07146.1 - 0.064 13.3 0.0 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 EGB07146.1 - 0.072 12.8 0.0 8.6 6.0 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein TsaE PF02367.17 EGB07146.1 - 0.1 12.6 0.0 9.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 EGB07146.1 - 0.11 11.1 0.0 7.6 5.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 EGB07146.1 - 0.12 11.8 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.18 EGB07146.1 - 0.13 11.5 0.0 4.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Septin KAP_NTPase PF07693.14 EGB07146.1 - 0.16 11.2 0.0 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain Guanylate_kin PF00625.21 EGB07146.1 - 0.17 11.6 0.0 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase SRPRB PF09439.10 EGB07146.1 - 0.17 11.3 0.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGB07146.1 - 0.2 11.4 0.0 25 4.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EGB07147.1 - 4.4e-39 133.9 0.0 7.6e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB07147.1 - 2.1e-09 37.0 0.0 4.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EGB07147.1 - 1.9e-07 31.0 0.0 1e-06 28.6 0.0 2.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 EGB07147.1 - 3.6e-06 27.0 0.2 3e-05 24.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGB07147.1 - 3.7e-05 23.5 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGB07147.1 - 9.7e-05 22.5 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGB07147.1 - 0.0002 20.7 0.0 0.0003 20.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGB07147.1 - 0.00029 21.1 0.4 0.13 12.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB07147.1 - 0.0011 19.4 0.6 0.044 14.2 0.6 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGB07147.1 - 0.018 14.6 0.5 3.2 7.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 EGB07147.1 - 0.027 14.0 0.0 0.37 10.3 0.1 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGB07147.1 - 0.032 14.8 0.0 0.059 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB07147.1 - 0.06 12.7 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGB07147.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EGB07147.1 - 0.079 12.3 0.5 2.1 7.7 0.2 2.2 1 1 1 2 2 2 0 KaiC AAA_14 PF13173.6 EGB07147.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 EGB07147.1 - 0.12 12.1 0.1 1.9 8.1 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 EGB07147.1 - 0.17 11.3 0.1 22 4.4 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein Metallophos PF00149.28 EGB07148.1 - 2.8e-38 132.5 0.1 3.7e-38 132.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGB07148.1 - 0.01 16.3 0.1 0.022 15.2 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGB07148.1 - 0.16 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SYS1 PF09801.9 EGB07149.1 - 6.5e-36 123.6 0.6 7.1e-36 123.5 0.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Yip1 PF04893.17 EGB07149.1 - 0.22 11.2 3.5 0.29 10.8 3.5 1.2 1 0 0 1 1 1 0 Yip1 domain Glyco_hydro_20 PF00728.22 EGB07150.1 - 1.5e-29 103.5 0.0 2e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGB07150.1 - 5.3e-12 46.6 0.0 1.5e-10 41.9 0.0 2.1 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGB07150.1 - 0.00025 21.8 0.0 0.00038 21.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4231 PF14015.6 EGB07151.1 - 0.00066 20.1 4.1 0.15 12.5 0.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4231) YesK PF14150.6 EGB07151.1 - 0.03 14.5 0.7 0.03 14.5 0.7 2.5 2 1 1 3 3 3 0 YesK-like protein DUF3357 PF11837.8 EGB07151.1 - 0.072 13.6 0.3 1.5 9.3 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) PhoLip_ATPase_C PF16212.5 EGB07151.1 - 0.074 12.8 5.0 0.096 12.4 5.0 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DHHC PF01529.20 EGB07151.1 - 1.2 9.2 6.4 2.1 8.4 1.3 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase RskA PF10099.9 EGB07151.1 - 2.5 8.3 7.7 11 6.3 7.7 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4094 PF13334.6 EGB07151.1 - 2.6 8.5 4.5 16 6.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) S_4TM PF18159.1 EGB07151.1 - 2.8 7.2 4.2 1.2 8.3 0.3 2.0 1 1 0 2 2 2 0 SMODS-associating 4TM effector domain Lig_chan PF00060.26 EGB07151.1 - 3.6 7.4 10.8 2 8.2 0.2 2.9 2 1 0 2 2 2 0 Ligand-gated ion channel Pro_isomerase PF00160.21 EGB07152.1 - 1.3e-43 149.0 0.0 1.5e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cupin_4 PF08007.12 EGB07153.1 - 4.1e-14 52.8 0.0 7.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein RINGv PF12906.7 EGB07153.1 - 0.00057 20.0 5.9 0.0013 18.8 5.9 1.7 1 0 0 1 1 1 1 RING-variant domain Cupin_8 PF13621.6 EGB07153.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGB07153.1 - 0.024 15.0 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGB07153.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_1 PF00190.22 EGB07153.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 EGB07153.1 - 0.18 11.5 0.0 0.54 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Peptidase_S28 PF05577.12 EGB07154.1 - 1.4e-54 185.6 0.0 1.6e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 EGB07154.1 - 0.00031 20.1 0.1 0.00055 19.3 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGB07154.1 - 0.0009 18.8 0.3 0.0013 18.2 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGB07154.1 - 0.001 18.8 0.7 0.0019 17.9 0.7 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 EGB07154.1 - 0.1 11.3 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 PS-10 peptidase S37 Abhydrolase_2 PF02230.16 EGB07154.1 - 0.19 11.5 0.1 0.3 10.8 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGB07154.1 - 0.41 11.2 15.5 0.57 10.7 15.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sulfatase PF00884.23 EGB07155.1 - 2.7e-20 73.0 0.0 3e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase PQ-loop PF04193.14 EGB07156.1 - 9.8e-18 63.7 0.3 1.4e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EGB07156.1 - 0.04 14.7 0.0 0.063 14.1 0.0 1.3 1 0 0 1 1 1 0 ER lumen protein retaining receptor Pro_isomerase PF00160.21 EGB07157.1 - 1.1e-39 136.2 0.0 1.3e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_S28 PF05577.12 EGB07158.1 - 3.8e-74 250.0 0.0 4.6e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 EGB07158.1 - 0.00055 19.3 0.1 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB07158.1 - 0.0013 18.5 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB07158.1 - 0.0015 18.0 0.3 0.0024 17.4 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 EGB07158.1 - 0.1 11.2 0.1 0.35 9.5 0.0 1.9 2 0 0 2 2 2 0 PS-10 peptidase S37 SAP PF02037.27 EGB07159.1 - 2.4e-09 36.7 2.4 1.6e-05 24.5 0.4 4.0 4 0 0 4 4 4 2 SAP domain DnaJ PF00226.31 EGB07159.1 - 6.4e-08 32.6 0.0 2e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain SHOCT PF09851.9 EGB07159.1 - 3.4e-07 29.8 3.5 1.4e-06 27.8 3.5 2.1 1 0 0 1 1 1 1 Short C-terminal domain DUF572 PF04502.13 EGB07159.1 - 0.87 9.1 8.1 0.28 10.8 3.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) ATP11 PF06644.11 EGB07159.1 - 1.5 8.5 5.5 3.3 7.4 5.5 1.5 1 0 0 1 1 1 0 ATP11 protein DUF983 PF06170.12 EGB07159.1 - 5.5 7.5 10.6 23 5.5 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF983) WD40 PF00400.32 EGB07160.1 - 1.2e-09 38.6 14.0 0.0003 21.5 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Sec16_C PF12931.7 EGB07160.1 - 2.4e-06 27.4 0.1 0.00012 21.8 0.1 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 EGB07160.1 - 3e-05 24.2 0.0 0.25 11.7 0.0 3.1 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PSI PF01437.25 EGB07160.1 - 1.9 9.1 4.4 0.63 10.6 0.6 2.2 2 0 0 2 2 2 0 Plexin repeat WD40 PF00400.32 EGB07161.1 - 1.6e-08 35.1 1.7 0.025 15.5 0.5 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB07161.1 - 0.0017 18.6 0.0 0.61 10.4 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Patatin PF01734.22 EGB07162.1 - 9.7e-06 25.9 1.8 3.3e-05 24.2 0.3 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase zf_C2H2_ZHX PF18387.1 EGB07162.1 - 0.00026 20.6 0.3 0.00056 19.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 EGB07162.1 - 0.26 12.2 1.3 0.9 10.6 1.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger SBF PF01758.16 EGB07163.1 - 1.8e-14 53.9 7.0 3.2e-14 53.0 7.0 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family NHL PF01436.21 EGB07163.1 - 0.028 14.4 0.0 2.8 8.2 0.0 3.3 3 0 0 3 3 3 0 NHL repeat SBF_like PF13593.6 EGB07163.1 - 0.98 8.7 11.7 2.3 7.4 11.6 1.5 1 1 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) Abhydrolase_6 PF12697.7 EGB07164.1 - 1.1e-21 78.5 14.5 1.3e-21 78.2 14.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB07164.1 - 8.5e-15 55.1 0.0 1.1e-13 51.4 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB07164.1 - 2.2e-14 53.3 0.1 1.1e-13 51.0 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGB07164.1 - 3.9e-07 30.4 0.0 9.4e-07 29.2 0.0 1.7 1 1 1 2 2 2 1 Thioesterase domain DUF676 PF05057.14 EGB07164.1 - 0.0019 17.8 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 EGB07164.1 - 0.0032 16.4 0.0 0.0057 15.6 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 EGB07164.1 - 0.032 13.9 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 EGB07164.1 - 0.041 13.6 0.4 0.084 12.6 0.4 1.5 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 EGB07164.1 - 0.067 13.0 1.2 0.12 12.2 0.8 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGB07164.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 EGB07164.1 - 0.091 12.3 0.1 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Enamelin PF15362.6 EGB07164.1 - 0.11 10.8 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Enamelin DUF3089 PF11288.8 EGB07164.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF5010 PF16402.5 EGB07164.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Lyase_1 PF00206.20 EGB07165.1 - 3.8e-77 259.8 0.0 5.8e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EGB07165.1 - 1.1e-17 64.6 1.4 2.8e-17 63.2 1.4 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FA_hydroxylase PF04116.13 EGB07166.1 - 5.8e-18 65.5 14.6 1.5e-17 64.2 14.6 1.8 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily PH PF00169.29 EGB07166.1 - 1e-13 51.7 0.0 1.2e-09 38.7 0.0 2.3 2 0 0 2 2 2 2 PH domain DUF599 PF04654.12 EGB07166.1 - 0.087 12.2 4.1 0.27 10.6 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF599 Pkinase PF00069.25 EGB07167.1 - 1.6e-44 152.3 0.0 1.8e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07167.1 - 6.1e-22 78.1 0.0 7.8e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB07167.1 - 0.00097 19.1 0.1 0.0027 17.7 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGB07167.1 - 0.0035 16.4 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGB07167.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGB07167.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Peptidase_M16 PF00675.20 EGB07168.1 - 5.3e-21 75.2 0.0 1.2e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGB07168.1 - 1.8e-09 37.9 0.2 4.9e-08 33.2 0.1 2.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain FYVE PF01363.21 EGB07169.1 - 1.7e-16 60.1 8.3 3.5e-16 59.1 8.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGB07169.1 - 0.54 10.5 2.2 1.1 9.4 2.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger LRR_8 PF13855.6 EGB07170.1 - 2.4e-13 49.6 0.2 2.7e-06 27.0 0.1 2.9 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EGB07170.1 - 3.5e-13 49.5 0.0 7.1e-05 23.1 0.0 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB07170.1 - 0.0088 16.5 0.0 59 4.8 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 EGB07170.1 - 0.031 14.3 0.0 6 7.0 0.0 3.4 1 1 3 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain Sel1 PF08238.12 EGB07171.1 - 5.9e-82 268.2 56.2 3.7e-09 36.9 0.2 16.5 16 0 0 16 16 16 11 Sel1 repeat zf-MYND PF01753.18 EGB07171.1 - 1e-18 67.1 50.0 6.3e-08 32.6 11.6 7.3 7 0 0 7 7 5 4 MYND finger Ecl1 PF12855.7 EGB07171.1 - 4.7e-05 24.6 26.7 0.98 10.6 2.0 4.2 4 0 0 4 4 4 4 ECL1/2/3 zinc binding proteins DUF4123 PF13503.6 EGB07171.1 - 0.0044 17.4 0.0 15 6.0 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4123) zf-RING_2 PF13639.6 EGB07171.1 - 0.0098 16.2 13.6 0.0098 16.2 13.6 7.2 7 0 0 7 7 6 4 Ring finger domain PDDEXK_10 PF07788.11 EGB07171.1 - 0.023 14.6 0.8 33 4.5 0.0 3.5 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily B12-binding_2 PF02607.17 EGB07171.1 - 0.16 12.4 2.2 54 4.3 0.0 4.3 4 0 0 4 4 4 0 B12 binding domain POTRA_TamA_1 PF17243.2 EGB07171.1 - 0.16 12.0 0.0 54 4.0 0.0 3.9 3 0 0 3 3 3 0 POTRA domain TamA domain 1 DUF410 PF04190.13 EGB07171.1 - 0.34 10.7 5.3 5.9 6.6 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF410) TPR_10 PF13374.6 EGB07171.1 - 0.39 10.6 11.3 8.6 6.4 0.1 7.1 5 0 0 5 5 5 0 Tetratricopeptide repeat CAP_N PF01213.19 EGB07171.1 - 0.44 10.0 18.2 8 5.8 0.6 4.2 4 0 0 4 4 4 0 Adenylate cyclase associated (CAP) N terminal Zn-C2H2_12 PF18112.1 EGB07171.1 - 2 8.9 0.0 2 8.9 0.0 7.0 8 0 0 8 8 7 0 Autophagy receptor zinc finger-C2H2 domain Ank_2 PF12796.7 EGB07172.1 - 6.9e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB07172.1 - 1.1e-05 25.9 0.0 2.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB07172.1 - 3.6e-05 24.0 0.0 0.19 12.2 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGB07172.1 - 0.00034 20.8 0.0 0.28 11.9 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Chlam_PMP PF02415.17 EGB07172.1 - 0.029 14.9 0.3 0.029 14.9 0.3 13.2 15 0 0 15 15 15 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TRP PF06011.12 EGB07172.1 - 0.051 12.3 3.8 0.29 9.8 0.4 2.3 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Ank_5 PF13857.6 EGB07172.1 - 0.1 13.0 0.0 0.34 11.3 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) MSC PF09402.10 EGB07172.1 - 1 8.7 3.2 2.3 7.6 3.2 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain AMP-binding PF00501.28 EGB07174.1 - 1.9e-75 254.1 0.1 5.1e-75 252.7 0.1 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Ribonucleas_3_3 PF14622.6 EGB07175.1 - 1.5e-22 80.1 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGB07175.1 - 7.4e-15 55.5 0.0 2.4e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EGB07175.1 - 1.7e-08 35.1 0.1 2.5e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EGB07175.1 - 0.033 14.4 0.2 0.098 12.9 0.2 1.8 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DeoC PF01791.9 EGB07175.1 - 0.062 12.9 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 DeoC/LacD family aldolase Tocopherol_cycl PF14249.6 EGB07176.1 - 4.3e-76 256.2 0.0 5.8e-62 209.8 0.2 2.1 1 1 1 2 2 2 2 Tocopherol cyclase Dynamin_N PF00350.23 EGB07178.1 - 6.8e-37 127.1 0.0 9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGB07178.1 - 8.7e-09 35.0 0.0 1.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EGB07178.1 - 6.2e-05 23.0 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB07178.1 - 0.0083 15.7 0.0 4.4 6.8 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.6 EGB07178.1 - 0.039 14.3 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGB07178.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 EGB07178.1 - 0.14 11.2 0.0 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_21 PF13304.6 EGB07178.1 - 0.22 11.3 0.0 0.38 10.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NDK PF00334.19 EGB07179.1 - 2e-23 82.9 0.0 2.4e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ion_trans_2 PF07885.16 EGB07180.1 - 6.3e-16 58.1 6.9 8.7e-16 57.7 6.9 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB07180.1 - 0.04 13.1 1.2 0.097 11.9 1.2 1.7 1 1 0 1 1 1 0 Ion transport protein Ricin_B_lectin PF00652.22 EGB07181.1 - 4.6e-10 39.8 0.0 1.1e-08 35.4 0.0 2.1 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGB07181.1 - 0.00072 20.2 0.1 0.0037 17.9 0.0 2.2 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like 2OG-FeII_Oxy_3 PF13640.6 EGB07182.1 - 4.6e-12 46.7 0.0 8.5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB07182.1 - 1e-05 25.9 0.0 2.4e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KRTAP PF11759.8 EGB07183.1 - 0.074 13.6 73.1 1.8e+04 -35.9 73.1 3.6 1 1 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 EGB07183.1 - 0.52 10.4 66.5 1.8e+04 -31.8 66.5 4.0 1 1 0 1 1 1 0 Keratin type II head Peptidase_C97 PF05903.14 EGB07184.1 - 5.9e-06 26.2 0.0 9.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain FHA PF00498.26 EGB07185.1 - 0.036 14.4 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 FHA domain RNA_pol_Rpc4 PF05132.14 EGB07185.1 - 1.2 9.5 3.8 3.4 8.1 3.8 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ion_trans PF00520.31 EGB07186.1 - 8.9e-17 61.1 12.0 1.3e-16 60.6 12.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB07186.1 - 3.6e-08 33.2 2.9 3.6e-08 33.2 2.9 2.4 3 0 0 3 3 3 1 Ion channel ZapC PF07126.12 EGB07186.1 - 0.034 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Cell-division protein ZapC PP28 PF10252.9 EGB07186.1 - 0.33 11.4 5.2 0.8 10.2 5.2 1.7 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Porphobil_deam PF01379.20 EGB07188.1 - 2e-49 167.9 0.1 2.7e-49 167.5 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain ABC_tran PF00005.27 EGB07189.1 - 9.8e-10 39.1 0.0 1.1e-09 38.9 0.0 1.0 1 0 0 1 1 1 1 ABC transporter EF-hand_8 PF13833.6 EGB07190.1 - 0.00015 21.5 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 EGB07190.1 - 0.073 13.5 0.0 13 6.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Ank_2 PF12796.7 EGB07191.1 - 3.3e-13 50.0 0.0 4.5e-09 36.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB07191.1 - 8.9e-12 45.3 0.0 2.1e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Glyco_hydro_20b PF02838.15 EGB07191.1 - 1.3e-10 42.2 0.0 3.3e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ank_3 PF13606.6 EGB07191.1 - 1.7e-10 40.2 0.5 0.01 16.3 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGB07191.1 - 5.4e-09 36.1 4.5 1.1e-05 25.6 0.4 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB07191.1 - 4.8e-05 23.6 6.2 0.0049 17.3 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Cys_Met_Meta_PP PF01053.20 EGB07193.1 - 1.4e-115 385.9 0.0 2.1e-115 385.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGB07193.1 - 2.8e-11 43.2 0.0 4.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGB07193.1 - 1.8e-06 27.2 0.0 2.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EGB07193.1 - 0.0034 15.9 0.0 0.005 15.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase WD40 PF00400.32 EGB07194.1 - 2.9e-45 151.3 27.9 7.9e-09 36.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB07194.1 - 5e-09 36.4 0.6 0.52 10.7 0.0 4.8 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB07194.1 - 0.0029 16.3 3.7 0.5 9.0 0.0 3.7 2 1 0 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGB07194.1 - 0.0095 14.5 0.0 0.34 9.4 0.1 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EGB07194.1 - 0.031 13.6 0.0 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain EF-hand_1 PF00036.32 EGB07195.1 - 1.4e-14 52.5 3.1 3.1e-06 26.4 1.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB07195.1 - 2.4e-12 47.1 0.7 2.9e-12 46.9 0.7 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB07195.1 - 7.6e-12 44.2 1.2 5e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB07195.1 - 1.1e-09 37.3 1.7 0.00037 19.9 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB07195.1 - 8.9e-09 35.1 1.9 0.002 17.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EGB07195.1 - 0.00067 19.6 0.9 0.45 10.5 0.0 2.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGB07195.1 - 0.016 15.5 0.1 0.022 15.1 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain DUF2017 PF09438.10 EGB07195.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) DUF4483 PF14825.6 EGB07196.1 - 5.6e-33 113.9 0.0 1.1e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) DnaJ PF00226.31 EGB07196.1 - 2.1e-08 34.2 0.0 4.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain IBN_N PF03810.19 EGB07197.1 - 1.6e-06 28.0 0.0 4.2e-05 23.4 0.0 2.8 2 1 1 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGB07197.1 - 0.00016 21.8 0.0 0.0015 18.6 0.0 2.4 2 0 0 2 2 2 1 Exportin 1-like protein Cse1 PF08506.10 EGB07197.1 - 0.0031 16.4 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 EGB07197.1 - 0.0052 16.9 0.2 0.62 10.3 0.0 2.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RRN3 PF05327.11 EGB07197.1 - 0.12 10.9 6.6 9 4.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 TetR_C_36 PF18598.1 EGB07197.1 - 0.35 10.8 5.2 7.7 6.5 0.1 4.4 4 1 1 5 5 5 0 Tetracyclin repressor-like, C-terminal domain SDA1 PF05285.12 EGB07197.1 - 3.6 6.9 10.1 5.9 6.2 10.1 1.2 1 0 0 1 1 1 0 SDA1 Bestrophin PF01062.21 EGB07198.1 - 7.2e-26 91.3 2.1 9.6e-26 90.8 2.1 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel 3-HAO PF06052.12 EGB07198.1 - 0.14 11.8 0.0 0.9 9.2 0.0 2.3 2 1 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase CHCH PF06747.13 EGB07199.1 - 2.4e-05 24.3 2.2 3.1e-05 24.0 2.2 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EGB07199.1 - 0.001 19.3 3.0 0.0031 17.8 3.0 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 EGB07199.1 - 0.018 14.7 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGB07199.1 - 0.023 14.7 2.0 2.4 8.2 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 EGB07199.1 - 0.044 14.1 2.6 0.75 10.2 2.9 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.17 EGB07199.1 - 0.07 13.4 0.6 0.096 12.9 0.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb KNOX1 PF03790.13 EGB07199.1 - 0.13 12.0 0.4 0.13 12.0 0.4 1.8 2 1 1 3 3 3 0 KNOX1 domain Glyco_transf_90 PF05686.12 EGB07201.1 - 0.0027 16.7 0.0 2 7.2 0.0 3.0 3 0 0 3 3 3 3 Glycosyl transferase family 90 Aminotran_3 PF00202.21 EGB07202.1 - 7.5e-110 367.4 0.0 8.8e-110 367.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 EGB07202.1 - 0.096 11.6 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Nsp1_C PF05064.13 EGB07203.1 - 1.4e-12 47.5 0.8 1.4e-12 47.5 0.8 2.6 3 0 0 3 3 3 1 Nsp1-like C-terminal region DUF1640 PF07798.11 EGB07203.1 - 0.0045 17.0 0.5 0.018 15.1 0.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) CENP-F_leu_zip PF10473.9 EGB07203.1 - 0.018 15.0 9.1 0.48 10.5 4.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 EGB07203.1 - 0.019 13.7 4.3 0.024 13.3 4.3 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 EGB07203.1 - 0.035 14.3 4.8 0.98 9.6 0.8 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 EGB07203.1 - 0.058 13.9 8.0 0.15 12.6 1.0 3.1 1 1 2 3 3 3 0 Spectrin repeat DUF948 PF06103.11 EGB07203.1 - 0.075 13.3 2.8 4 7.8 0.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1638 PF07796.11 EGB07203.1 - 0.076 13.1 0.1 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) DUF724 PF05266.14 EGB07203.1 - 0.11 12.3 4.1 1.7 8.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Bacillus_HBL PF05791.11 EGB07203.1 - 0.12 12.2 4.1 13 5.6 0.1 3.0 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) COG5 PF10392.9 EGB07203.1 - 0.13 12.4 3.8 1.9 8.7 0.7 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Sec34 PF04136.15 EGB07203.1 - 0.16 11.9 2.9 11 5.9 0.2 2.7 2 1 1 3 3 3 0 Sec34-like family Baculo_PEP_C PF04513.12 EGB07203.1 - 0.18 11.8 3.7 7.4 6.6 1.1 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 EGB07203.1 - 0.21 12.1 9.3 1.6 9.3 1.7 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EGB07203.1 - 0.29 11.4 7.9 0.63 10.3 1.9 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 EGB07203.1 - 0.36 11.3 5.6 31 5.1 0.1 3.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.6 EGB07203.1 - 0.41 11.0 7.6 0.14 12.4 0.7 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 EGB07203.1 - 0.45 10.9 4.5 40 4.7 0.0 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 EGB07203.1 - 0.57 10.7 5.5 8.4 6.9 2.4 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 BST2 PF16716.5 EGB07203.1 - 0.68 10.5 6.7 6.8 7.3 0.3 2.9 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 Phage_lysis PF03245.13 EGB07203.1 - 0.72 10.0 8.4 0.28 11.3 1.5 2.3 1 1 0 2 2 2 0 Bacteriophage Rz lysis protein THOC7 PF05615.13 EGB07203.1 - 0.87 9.9 8.6 3.5 7.9 2.5 2.6 2 2 0 2 2 2 0 Tho complex subunit 7 FapA PF03961.13 EGB07203.1 - 0.9 8.1 3.2 1.5 7.3 0.3 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Nnf1 PF03980.14 EGB07203.1 - 2 8.8 8.8 3.7 8.0 2.2 3.1 2 2 0 2 2 2 0 Nnf1 TolA_bind_tri PF16331.5 EGB07203.1 - 4.1 7.5 8.9 0.79 9.8 0.2 3.3 3 1 0 3 3 3 0 TolA binding protein trimerisation ESSS PF10183.9 EGB07205.1 - 0.015 15.5 0.0 0.056 13.7 0.0 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Reticulon PF02453.17 EGB07205.1 - 0.15 12.0 0.1 0.37 10.7 0.2 1.6 2 0 0 2 2 2 0 Reticulon adh_short PF00106.25 EGB07206.1 - 2.4e-33 115.2 0.8 3e-33 114.9 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB07206.1 - 2.5e-23 82.9 0.3 3.4e-23 82.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB07206.1 - 2.4e-06 27.6 0.2 3.8e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB07206.1 - 0.012 15.1 1.1 0.058 12.8 1.1 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGB07206.1 - 0.031 13.4 0.3 0.05 12.7 0.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGB07206.1 - 0.18 11.7 0.3 0.54 10.1 0.3 1.7 1 1 0 1 1 1 0 NAD(P)H-binding 2OG-FeII_Oxy_4 PF13661.6 EGB07208.1 - 8.3e-16 58.4 1.0 1.6e-15 57.5 1.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGB07208.1 - 5.2e-10 40.1 1.7 1.4e-09 38.7 1.7 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 EGB07208.1 - 0.2 10.9 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Sec63 PF02889.16 EGB07209.1 - 1.3e-88 296.5 0.0 1.5e-64 217.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGB07209.1 - 5.3e-49 166.4 0.0 3.4e-23 82.3 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EGB07209.1 - 5.8e-23 81.8 0.0 3.1e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGB07209.1 - 4.7e-14 52.7 0.0 1.1e-06 29.0 0.0 3.6 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGB07209.1 - 5.6e-08 33.1 0.1 0.057 13.7 0.1 4.1 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 EGB07209.1 - 0.00011 21.4 0.0 0.12 11.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 EGB07209.1 - 0.00035 20.2 0.4 0.043 13.4 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGB07209.1 - 0.0004 20.7 0.0 0.24 11.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGB07209.1 - 0.002 17.9 0.2 1.8 8.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 EGB07209.1 - 0.015 14.7 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 EGB07209.1 - 0.035 13.6 0.0 7.9 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGB07209.1 - 0.14 11.9 0.0 19 5.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Ribosomal_S14 PF00253.21 EGB07210.1 - 1.4e-14 53.6 5.4 1.5e-14 53.4 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e C1_2 PF03107.16 EGB07210.1 - 0.14 12.5 1.5 0.19 12.1 1.5 1.3 1 1 0 1 1 1 0 C1 domain Cupin_8 PF13621.6 EGB07211.1 - 4.1e-16 59.4 0.0 2.3e-15 57.0 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB07211.1 - 0.0008 19.0 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 EGB07211.1 - 0.0063 16.9 0.0 0.031 14.7 0.0 2.1 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGB07211.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Cupin domain VCBS PF13517.6 EGB07212.1 - 3.7e-98 322.1 243.3 5.6e-09 36.5 7.8 23.6 6 4 18 24 24 24 21 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella REJ PF02010.15 EGB07212.1 - 2.9e-26 92.3 0.0 6.8e-26 91.1 0.0 1.5 1 1 0 1 1 1 1 REJ domain AbfS_sensor PF18225.1 EGB07212.1 - 1.3e-07 31.4 0.0 58 3.7 0.0 10.5 13 0 0 13 13 13 0 Sensor histidine kinase (AbfS) sensor domain DNA_methylase PF00145.17 EGB07212.1 - 0.036 13.4 0.0 0.082 12.2 0.0 1.5 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Cwf_Cwc_15 PF04889.12 EGB07212.1 - 2.6 7.7 19.8 6.2 6.5 19.8 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein dCache_1 PF02743.18 EGB07213.1 - 3.3e-06 27.1 0.0 5.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Cache domain Furin-like_2 PF15913.5 EGB07213.1 - 3.4 7.9 11.2 24 5.1 5.8 2.9 2 1 0 2 2 2 0 Furin-like repeat, cysteine-rich Ephrin_rec_like PF07699.13 EGB07213.1 - 8.7 6.2 15.1 2.4 8.0 1.7 3.7 2 1 1 3 3 3 0 Putative ephrin-receptor like Oxidored_molyb PF00174.19 EGB07214.1 - 3.3e-41 140.8 0.1 5.8e-41 140.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGB07214.1 - 8.5e-25 87.4 0.0 1.9e-24 86.2 0.0 1.6 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain AIG2_2 PF13772.6 EGB07214.1 - 2.4e-05 24.6 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AIG2-like family Pyr_redox_2 PF07992.14 EGB07215.1 - 1.4e-14 54.0 0.0 2.5e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGB07215.1 - 0.005 16.8 0.8 0.39 10.7 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGB07215.1 - 0.021 15.4 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB07215.1 - 0.16 11.2 0.1 3.2 6.9 0.1 2.0 1 1 0 2 2 2 0 FAD binding domain Peptidase_M17 PF00883.21 EGB07216.1 - 9.4e-91 304.3 0.1 1e-90 304.2 0.1 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain TrbI PF03743.14 EGB07216.1 - 3.2 7.5 5.3 0.7 9.7 0.9 1.8 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein SH3_9 PF14604.6 EGB07217.1 - 1.5e-13 50.3 0.1 1.7e-13 50.2 0.1 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB07217.1 - 2.5e-12 46.2 0.0 2.8e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGB07217.1 - 8.5e-09 35.0 0.0 8.8e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain VWA_2 PF13519.6 EGB07218.1 - 4.7e-06 27.2 0.0 1.2e-05 25.9 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGB07218.1 - 0.007 15.8 0.2 0.015 14.7 0.2 1.5 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein AA_permease PF00324.21 EGB07220.1 - 1.9e-55 188.3 31.5 2.4e-55 188.0 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGB07220.1 - 8.9e-16 57.7 38.3 1.2e-15 57.4 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease Na_H_antiport_1 PF06965.12 EGB07221.1 - 3.3e-48 164.4 11.6 3.3e-48 164.4 11.6 1.7 2 0 0 2 2 2 1 Na+/H+ antiporter 1 ABC_tran PF00005.27 EGB07222.1 - 1.1e-33 116.6 0.0 1.5e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB07222.1 - 6.7e-06 26.1 0.5 0.034 14.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB07222.1 - 8e-06 26.3 1.4 1.6e-05 25.3 1.4 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGB07222.1 - 2.9e-05 23.6 0.5 0.0014 18.1 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 EGB07222.1 - 0.0005 19.8 0.0 0.00062 19.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 EGB07222.1 - 0.0056 15.7 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EGB07222.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 EGB07222.1 - 0.0087 16.1 0.0 0.056 13.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB07222.1 - 0.018 15.3 0.1 0.049 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB07222.1 - 0.042 14.4 0.0 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGB07222.1 - 0.052 13.7 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGB07222.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGB07222.1 - 0.073 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB07222.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EGB07222.1 - 0.096 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 EGB07222.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.20 EGB07222.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PRK PF00485.18 EGB07222.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EGB07222.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 EGB07222.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Neur_chan_LBD PF02931.23 EGB07223.1 - 1e-06 28.4 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Bax1-I PF01027.20 EGB07224.1 - 6.1e-32 111.1 13.3 6.7e-32 111.0 13.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 EGB07224.1 - 0.13 10.6 5.4 0.15 10.4 5.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MgtE PF01769.16 EGB07224.1 - 0.37 11.2 8.2 0.71 10.3 8.2 1.7 1 1 0 1 1 1 0 Divalent cation transporter RDD PF06271.12 EGB07224.1 - 0.58 10.4 8.4 1.4 9.1 8.4 1.9 1 1 0 1 1 1 0 RDD family Raffinose_syn PF05691.12 EGB07225.1 - 0.00018 19.4 0.0 0.00025 19.0 0.0 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 TIP39 PF14980.6 EGB07226.1 - 0.92 9.4 0.0 0.92 9.4 0.0 3.2 3 0 0 3 3 3 0 TIP39 peptide FKBP_C PF00254.28 EGB07227.1 - 1.8e-12 47.4 0.0 2.2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SF3A2 PF16835.5 EGB07228.1 - 1.1e-36 125.1 0.0 1.6e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGB07228.1 - 9.7e-07 29.0 1.0 2e-06 28.0 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EGB07228.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein MR_MLE_C PF13378.6 EGB07229.1 - 1.6e-46 158.6 0.0 2.4e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGB07229.1 - 1.7e-11 44.4 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ion_trans PF00520.31 EGB07231.1 - 1.9e-17 63.3 0.3 3.3e-17 62.5 0.3 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB07231.1 - 2.6e-13 49.7 0.6 7.8e-13 48.2 0.6 1.7 1 0 0 1 1 1 1 Ion channel EF-hand_1 PF00036.32 EGB07231.1 - 4.6e-11 41.4 0.1 0.00011 21.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB07231.1 - 6e-10 38.2 0.0 0.0004 19.8 0.0 2.7 2 0 0 2 2 2 2 EF hand cNMP_binding PF00027.29 EGB07231.1 - 4.4e-09 36.3 0.3 1e-07 31.9 0.1 2.7 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain EF-hand_6 PF13405.6 EGB07231.1 - 2.3e-08 33.3 0.2 0.00027 20.6 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGB07231.1 - 3.3e-08 33.8 0.0 8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB07231.1 - 6.5e-07 29.1 0.0 0.054 13.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB07231.1 - 0.0013 19.1 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGB07231.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF3079 PF11278.8 EGB07231.1 - 0.14 12.0 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) tRNA_U5-meth_tr PF05958.11 EGB07232.1 - 1.9e-100 336.4 0.0 2.2e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EGB07232.1 - 0.00021 21.9 0.0 0.00068 20.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB07232.1 - 0.0034 18.0 0.0 0.015 15.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 EGB07232.1 - 0.026 13.6 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_15 PF09445.10 EGB07232.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Kelch_1 PF01344.25 EGB07233.1 - 2.8e-24 84.4 3.9 4.3e-05 23.0 0.0 6.5 7 1 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 EGB07233.1 - 1.2e-19 69.8 0.0 0.003 17.8 0.0 6.3 4 2 2 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EGB07233.1 - 9.4e-16 57.7 8.0 0.00035 20.8 0.1 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGB07233.1 - 1.3e-14 53.9 0.3 0.0038 17.2 0.0 6.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB07233.1 - 9.6e-07 28.7 1.6 1.7 8.7 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EGB07233.1 - 5.8e-06 26.1 0.0 0.091 12.8 0.0 5.4 6 0 0 6 6 6 1 Kelch motif Glyoxal_oxid_N PF07250.11 EGB07233.1 - 3.2e-05 23.3 0.0 0.038 13.2 0.0 3.2 3 1 1 4 4 4 2 Glyoxal oxidase N-terminus F-box PF00646.33 EGB07233.1 - 7.4e-05 22.5 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 EGB07233.1 - 0.035 14.6 0.6 0.035 14.6 0.6 3.8 4 0 0 4 4 4 0 PQQ-like domain Ras PF00071.22 EGB07234.1 - 4.6e-63 211.6 1.1 5.3e-63 211.5 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB07234.1 - 3.9e-35 120.7 0.4 6e-35 120.1 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB07234.1 - 4.4e-19 68.6 0.1 5.7e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGB07234.1 - 1.2e-06 28.2 0.4 2.7e-06 27.1 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB07234.1 - 1.4e-05 24.6 0.1 1.6e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB07234.1 - 2.5e-05 24.3 0.3 4.4e-05 23.5 0.2 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB07234.1 - 0.00015 21.3 0.1 0.00019 20.9 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGB07234.1 - 0.0009 18.8 0.1 0.0025 17.4 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B TMP-TENI PF02581.17 EGB07234.1 - 0.012 15.0 0.0 1.4 8.2 0.0 2.1 1 1 1 2 2 2 0 Thiamine monophosphate synthase RsgA_GTPase PF03193.16 EGB07234.1 - 0.016 15.1 0.0 5.1 7.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 EGB07234.1 - 0.1 13.0 0.1 1.4 9.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB07234.1 - 0.18 12.2 0.1 1 9.7 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EGB07234.1 - 0.21 10.7 1.2 5.5 6.0 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit M16C_assoc PF08367.11 EGB07235.1 - 3.2e-51 173.9 0.0 5.2e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EGB07235.1 - 5.6e-22 78.6 0.0 3.3e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGB07235.1 - 0.00017 21.6 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) NUDIX PF00293.28 EGB07236.1 - 7.4e-12 45.5 0.2 9e-12 45.2 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EGB07236.1 - 1.9e-07 30.6 5.9 3.1e-07 29.9 5.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 EGB07236.1 - 0.0061 16.6 0.8 0.011 15.8 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon Chorismate_synt PF01264.21 EGB07237.1 - 3.8e-136 453.1 0.6 4.4e-136 452.9 0.6 1.0 1 0 0 1 1 1 1 Chorismate synthase SUV3_C PF12513.8 EGB07238.1 - 3.4e-11 42.9 0.3 7.1e-11 41.9 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 EGB07238.1 - 3.4e-08 33.2 0.2 6.5e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 EGB07238.1 - 3.5e-08 33.8 0.0 7.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SH3_1 PF00018.28 EGB07239.1 - 1.1e-10 40.9 0.0 1.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGB07239.1 - 4.5e-09 36.0 0.0 7.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGB07239.1 - 1.2e-05 24.9 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Acyltransferase PF01553.21 EGB07240.1 - 1.9e-18 66.4 0.0 3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase zf-C3HC4_3 PF13920.6 EGB07241.1 - 2.4e-06 27.3 7.9 2.4e-06 27.3 7.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Tmemb_185A PF10269.9 EGB07241.1 - 6.5e-05 22.7 0.0 0.076 12.7 0.0 2.5 2 0 0 2 2 2 2 Transmembrane Fragile-X-F protein zf-C3HC4_2 PF13923.6 EGB07241.1 - 4 7.4 7.1 9.4 6.2 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.18 EGB07242.1 - 0.00044 19.5 15.3 0.042 13.2 3.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 EGB07242.1 - 0.11 12.6 11.2 0.22 11.6 0.6 2.7 3 0 0 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EGB07242.1 - 0.16 11.8 15.1 1.4 8.7 4.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Metallophos_2 PF12850.7 EGB07243.1 - 1.3e-06 28.7 0.0 0.0041 17.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGB07243.1 - 0.0021 18.6 0.0 0.049 14.1 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Methyltransf_30 PF05430.11 EGB07243.1 - 0.052 13.4 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase CLP1_P PF16575.5 EGB07244.1 - 2.9e-52 177.2 0.0 4e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EGB07244.1 - 7.8e-26 90.8 0.0 1.4e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EGB07244.1 - 5.1e-22 77.9 0.0 7.4e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 EGB07244.1 - 0.00071 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGB07244.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGB07244.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EGB07244.1 - 0.046 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 EGB07244.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EGB07244.1 - 0.072 13.3 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB07244.1 - 0.082 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 EGB07244.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain VWA_2 PF13519.6 EGB07245.1 - 0.01 16.5 0.0 0.15 12.8 0.0 2.6 2 1 0 2 2 2 0 von Willebrand factor type A domain Pkinase PF00069.25 EGB07246.1 - 2.6e-61 207.3 0.0 2.9e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07246.1 - 4.9e-44 150.6 0.0 6e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB07246.1 - 0.0071 15.7 0.1 0.25 10.6 0.1 2.7 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB07246.1 - 0.029 13.1 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 EGB07247.1 - 1.5e-24 85.8 14.3 1.3e-05 25.8 0.5 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB07247.1 - 1.1e-06 28.9 0.2 0.015 15.6 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB07247.1 - 6.8e-05 21.7 1.1 1.9 7.0 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Rdx PF10262.9 EGB07248.1 - 1.2e-08 35.0 0.0 3e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Rdx family Pkinase PF00069.25 EGB07249.1 - 1.8e-49 168.5 0.0 2.3e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07249.1 - 7.4e-24 84.4 0.1 1.8e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB07249.1 - 7.1e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB07249.1 - 0.00024 20.5 0.2 0.0026 17.1 0.2 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB07249.1 - 0.00037 19.9 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB07249.1 - 0.0014 18.6 0.1 0.0041 17.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB07249.1 - 0.0055 15.5 0.0 0.0085 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ribosomal_L16 PF00252.18 EGB07250.1 - 4.2e-39 133.6 0.2 5.2e-39 133.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF4812 PF16071.5 EGB07250.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) FSH1 PF03959.13 EGB07251.1 - 4e-16 59.3 0.0 5.7e-14 52.3 0.0 2.2 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Ank_5 PF13857.6 EGB07251.1 - 0.00011 22.4 0.2 0.0011 19.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Abhydrolase_1 PF00561.20 EGB07251.1 - 0.00011 21.9 0.0 0.087 12.4 0.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold F-box-like PF12937.7 EGB07251.1 - 0.0002 21.2 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like Abhydrolase_2 PF02230.16 EGB07251.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ank_2 PF12796.7 EGB07251.1 - 0.01 16.4 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 EGB07251.1 - 0.012 16.0 0.0 0.062 13.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Hydrolase_4 PF12146.8 EGB07251.1 - 0.014 14.6 0.4 3.1 7.0 0.0 2.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 F-box PF00646.33 EGB07251.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 F-box domain RRM_3 PF08777.11 EGB07252.1 - 6.9e-17 61.4 0.0 1.4e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif La PF05383.17 EGB07252.1 - 3.3e-09 36.6 0.0 6.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGB07252.1 - 6.8e-05 22.6 0.1 0.068 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 EGB07253.1 - 1.2e-98 330.1 0.0 1.4e-98 329.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB07253.1 - 1.3e-32 112.8 0.0 2e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding PIN_9 PF18477.1 EGB07253.1 - 0.13 12.6 0.3 1.2 9.4 0.0 2.6 2 1 1 3 3 3 0 PIN like domain AAA PF00004.29 EGB07254.1 - 2.3e-37 128.3 0.0 3e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB07254.1 - 4.6e-08 33.6 1.4 1.4e-05 25.5 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB07254.1 - 8.2e-06 26.1 0.4 0.002 18.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 EGB07254.1 - 2.6e-05 23.9 2.3 6.8e-05 22.6 2.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB07254.1 - 0.00013 21.9 0.2 0.00073 19.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGB07254.1 - 0.00016 21.9 0.0 0.00031 20.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGB07254.1 - 0.00027 20.7 0.0 0.00067 19.4 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGB07254.1 - 0.00068 18.9 0.2 0.0016 17.7 0.1 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGB07254.1 - 0.0012 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGB07254.1 - 0.0015 18.3 0.0 0.0039 16.9 0.0 1.6 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 EGB07254.1 - 0.0022 18.2 0.0 0.0048 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGB07254.1 - 0.0027 17.8 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGB07254.1 - 0.0053 16.7 0.3 0.011 15.6 0.3 1.8 1 1 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 EGB07254.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGB07254.1 - 0.0074 16.8 0.0 0.011 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGB07254.1 - 0.011 16.0 0.1 0.014 15.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EGB07254.1 - 0.012 15.1 0.3 0.068 12.6 0.2 1.9 1 1 1 2 2 2 0 PhoH-like protein CPT PF07931.12 EGB07254.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EGB07254.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase TsaE PF02367.17 EGB07254.1 - 0.024 14.7 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGB07254.1 - 0.044 13.2 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGB07254.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGB07254.1 - 0.075 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGB07254.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EGB07254.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 KaiC DUF815 PF05673.13 EGB07254.1 - 0.2 10.8 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 EGB07254.1 - 0.22 10.9 0.0 4.4 6.7 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein Methyltransf_11 PF08241.12 EGB07255.1 - 3e-19 69.5 0.0 8.1e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB07255.1 - 8.3e-17 61.7 0.0 2.1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.10 EGB07255.1 - 1.1e-16 60.8 0.7 1.1e-16 60.8 0.7 2.1 2 0 0 2 2 2 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 EGB07255.1 - 5.5e-15 55.5 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB07255.1 - 4.6e-11 42.5 0.0 6.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGB07255.1 - 3e-10 40.2 0.0 4.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB07255.1 - 5e-10 39.1 0.0 7.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGB07255.1 - 4.2e-07 30.6 0.0 1e-06 29.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGB07255.1 - 0.025 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ceramidase_alk PF04734.13 EGB07256.1 - 6.7e-166 552.9 0.0 8.2e-166 552.6 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGB07256.1 - 2.8e-28 98.9 0.0 5.8e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Aldolase_II PF00596.21 EGB07257.1 - 5.6e-43 147.0 0.0 5.6e-27 94.9 0.0 2.2 2 0 0 2 2 2 2 Class II Aldolase and Adducin N-terminal domain TBCC PF07986.12 EGB07258.1 - 8.4e-35 119.1 0.0 1.1e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 EGB07258.1 - 0.047 13.3 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal HIPIP PF01355.17 EGB07258.1 - 0.28 11.6 6.2 27 5.2 0.0 3.4 2 1 1 3 3 3 0 High potential iron-sulfur protein tRNA-synt_1 PF00133.22 EGB07259.1 - 1.4e-68 231.6 0.0 1.5e-45 155.6 0.0 4.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EGB07259.1 - 9.5e-62 207.8 0.0 1.3e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EGB07259.1 - 2.2e-24 86.0 0.0 5.4e-17 61.6 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGB07259.1 - 1.9e-14 53.9 0.0 2e-13 50.6 0.0 2.2 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGB07259.1 - 1.6e-05 24.4 0.0 0.016 14.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 EGB07259.1 - 0.11 11.4 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.25 EGB07259.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) CSD PF00313.22 EGB07260.1 - 5.1e-19 67.9 0.0 7e-11 41.8 0.1 2.4 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain SAM_2 PF07647.17 EGB07260.1 - 2e-06 27.8 0.0 6.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) OB_RNB PF08206.11 EGB07260.1 - 2.5e-05 23.8 0.6 9.7e-05 22.0 0.3 2.0 2 0 0 2 2 2 1 Ribonuclease B OB domain SAM_1 PF00536.30 EGB07260.1 - 0.00098 19.5 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Bac_rhodopsin PF01036.18 EGB07260.1 - 0.044 13.4 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein Spermine_synth PF01564.17 EGB07261.1 - 4.4e-59 199.1 0.0 7.8e-59 198.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGB07261.1 - 3.4e-21 74.9 0.0 6e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EGB07261.1 - 0.055 14.2 1.3 0.11 13.2 0.4 2.1 2 1 0 2 2 2 0 Methyltransferase domain F_actin_cap_B PF01115.17 EGB07262.1 - 1.3e-97 326.1 0.0 1.5e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 EGB07262.1 - 0.019 14.4 0.0 0.098 12.1 0.0 2.0 1 1 0 1 1 1 0 F-actin capping protein alpha subunit PET10 PF17316.2 EGB07262.1 - 0.067 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Petite colonies protein 10 Proteasome PF00227.26 EGB07264.1 - 4.3e-58 196.0 0.0 5e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB07264.1 - 0.012 15.2 1.1 0.029 14.0 0.0 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature tRNA-synt_1c PF00749.21 EGB07265.1 - 5e-100 334.4 0.0 7.4e-100 333.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CTP_transf_1 PF01148.20 EGB07265.1 - 2.4e-46 158.7 10.9 3.6e-46 158.1 10.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family tRNA-synt_1c_C PF03950.18 EGB07265.1 - 3.5e-32 111.7 0.0 5.6e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 EGB07265.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain IHABP4_N PF16174.5 EGB07265.1 - 4.7 7.8 20.1 0.67 10.5 15.3 2.0 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal hnRNP_Q_AcD PF18360.1 EGB07266.1 - 6.9e-13 48.4 0.0 2.9e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF3235 PF11574.8 EGB07266.1 - 5.8 7.8 8.1 0.41 11.5 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) GHMP_kinases_C PF08544.13 EGB07267.1 - 7.4e-09 35.9 0.5 7.4e-09 35.9 0.5 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGB07267.1 - 2.8e-07 30.7 0.6 2.8e-07 30.7 0.6 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain Acetyltransf_6 PF13480.7 EGB07267.1 - 0.15 12.3 3.3 0.45 10.7 0.2 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Cu-oxidase_3 PF07732.15 EGB07268.1 - 8.1e-28 96.8 0.3 1.4e-27 96.1 0.3 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 EGB07268.1 - 8.9e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGB07268.1 - 0.00038 20.2 2.0 0.0046 16.7 2.0 2.2 1 1 0 1 1 1 1 Multicopper oxidase Hexapep PF00132.24 EGB07269.1 - 1.1e-13 50.3 8.9 1.9e-07 30.5 1.0 2.6 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 EGB07269.1 - 5.5e-10 39.6 0.3 8.4e-10 39.0 0.3 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 EGB07269.1 - 1.1e-06 28.3 11.3 3.1e-06 26.8 0.7 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase adh_short_C2 PF13561.6 EGB07270.1 - 1.3e-25 90.3 14.1 1.7e-23 83.4 7.0 3.4 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB07270.1 - 6e-21 74.8 3.3 6e-21 74.8 3.3 3.4 3 1 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 EGB07270.1 - 4.7e-16 59.2 2.0 2.8e-13 50.2 0.3 2.8 2 0 0 2 2 2 2 KR domain DUF2046 PF09755.9 EGB07270.1 - 0.0058 15.9 21.6 0.24 10.6 14.9 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Epimerase PF01370.21 EGB07270.1 - 0.027 13.9 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 EGB07270.1 - 0.052 13.8 0.4 0.052 13.8 0.4 3.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain TPR_12 PF13424.6 EGB07271.1 - 4.3e-88 289.7 52.6 1.5e-16 60.4 0.1 6.8 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGB07271.1 - 9.6e-51 168.4 35.5 2.6e-06 27.1 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.6 EGB07271.1 - 1.2e-25 87.6 25.9 0.00045 20.1 0.0 9.9 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07271.1 - 2.9e-20 70.7 39.0 0.0064 16.5 0.1 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGB07271.1 - 3.9e-20 70.7 29.4 0.015 15.1 0.0 9.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGB07271.1 - 1.3e-17 62.9 38.9 0.007 17.1 1.2 9.3 5 4 4 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07271.1 - 6.6e-17 60.3 17.4 0.032 14.4 0.0 9.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07271.1 - 7.2e-14 52.1 20.7 6.9e-05 23.3 1.7 6.7 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB07271.1 - 9.9e-11 42.1 37.2 0.00031 21.3 8.0 7.7 5 4 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGB07271.1 - 2.9e-09 36.7 4.9 1.1 9.8 0.0 7.8 6 3 1 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB07271.1 - 3e-09 36.7 13.9 1e-05 25.1 5.1 3.0 1 1 1 2 2 2 2 MalT-like TPR region ANAPC3 PF12895.7 EGB07271.1 - 4.7e-05 23.5 5.3 0.31 11.3 0.0 5.4 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGB07271.1 - 6e-05 23.4 14.9 5.5 7.9 0.0 7.9 8 1 1 9 9 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGB07271.1 - 0.00048 19.5 0.3 13 5.4 0.0 5.8 6 0 0 6 6 5 0 SHNi-TPR DUF627 PF04781.12 EGB07271.1 - 0.0013 18.7 1.8 0.12 12.4 0.6 3.8 2 1 0 2 2 2 1 Protein of unknown function (DUF627) TPR_11 PF13414.6 EGB07271.1 - 0.0031 17.1 12.7 10 5.9 0.0 7.2 8 0 0 8 8 8 0 TPR repeat T2SSF PF00482.23 EGB07271.1 - 0.0069 16.3 1.2 0.5 10.3 0.0 3.7 3 1 1 4 4 4 1 Type II secretion system (T2SS), protein F DUF3856 PF12968.7 EGB07271.1 - 0.014 15.4 0.3 0.16 12.1 0.1 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 EGB07271.1 - 0.015 15.3 5.7 3.9 7.6 0.0 5.2 5 2 1 6 6 5 0 MIT (microtubule interacting and transport) domain Gln_amidase PF15644.6 EGB07271.1 - 0.021 15.8 0.1 0.49 11.4 0.1 2.8 1 1 1 2 2 2 0 Papain fold toxin 1, glutamine deamidase DUF4404 PF14357.6 EGB07271.1 - 0.03 14.9 0.3 20 5.9 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) ANAPC5 PF12862.7 EGB07271.1 - 0.05 13.7 0.1 14 5.8 0.0 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 EGB07271.1 - 0.15 12.8 30.0 1.5 9.7 1.5 7.0 7 0 0 7 7 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EGB07271.1 - 1.7 8.5 5.1 60 3.5 0.1 3.8 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Bestrophin PF01062.21 EGB07272.1 - 6.2e-13 48.8 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SMK-1 PF04802.15 EGB07273.1 - 4.6e-28 98.4 0.0 3.4e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 Med3 PF11593.8 EGB07273.1 - 1.7 7.8 3.2 3 6.9 3.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Melibiase_2 PF16499.5 EGB07274.1 - 5.5e-44 150.4 0.0 2e-43 148.6 0.0 1.8 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 EGB07274.1 - 0.0074 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Melibiase DUF218 PF02698.17 EGB07275.1 - 0.00016 21.7 0.0 0.00021 21.3 0.0 1.3 1 1 0 1 1 1 1 DUF218 domain SepSecS PF05889.13 EGB07276.1 - 1e-111 373.4 0.0 7.8e-110 367.2 0.0 2.3 1 1 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 EGB07276.1 - 0.0021 17.4 0.2 0.0036 16.6 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2002 PF09400.10 EGB07276.1 - 0.036 14.1 0.1 0.099 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) DUF1627 PF07789.12 EGB07276.1 - 0.1 12.3 0.5 0.36 10.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1627) Abhydrolase_6 PF12697.7 EGB07276.1 - 2.6 8.6 11.3 3.3 8.2 9.7 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-MYND PF01753.18 EGB07277.1 - 1.4e-14 53.9 31.3 1.9e-10 40.6 12.9 2.7 2 0 0 2 2 2 2 MYND finger Ank_4 PF13637.6 EGB07277.1 - 9.5e-10 38.8 0.0 0.00032 21.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB07277.1 - 1.9e-07 31.6 0.0 6.3e-06 26.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB07277.1 - 7.8e-07 29.3 0.1 3.3e-05 24.1 0.1 3.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB07277.1 - 2.7e-05 24.4 3.2 0.72 10.4 0.0 5.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGB07277.1 - 5.2e-05 23.3 0.1 0.16 12.6 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat Hydrolase PF00702.26 EGB07277.1 - 0.1 12.9 0.8 1.4 9.1 0.1 3.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Amidohydro_1 PF01979.20 EGB07278.1 - 2.9e-16 59.7 0.3 4.1e-16 59.2 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGB07278.1 - 1.4e-05 24.8 6.6 0.00062 19.3 0.9 2.6 3 0 0 3 3 3 2 Amidohydrolase family DNA_pol_A PF00476.20 EGB07280.1 - 4.6e-77 259.6 0.0 6.4e-75 252.6 0.0 3.6 3 1 0 3 3 3 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EGB07280.1 - 1.8e-08 34.3 0.0 5.5e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Tyrosinase PF00264.20 EGB07281.1 - 1.5e-20 74.5 2.0 4e-09 37.1 0.4 2.4 2 0 0 2 2 2 2 Common central domain of tyrosinase PhyH PF05721.13 EGB07281.1 - 1.5e-11 45.0 2.9 3.3e-10 40.6 0.0 3.6 3 0 0 3 3 3 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3040 PF11239.8 EGB07281.1 - 0.13 12.5 3.5 0.71 10.2 3.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) AhpC-TSA_2 PF13911.6 EGB07283.1 - 1.4e-08 34.8 0.0 2.6e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGB07283.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family AMP-binding PF00501.28 EGB07284.1 - 2.5e-79 266.8 0.6 2.5e-79 266.8 0.6 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Exo_endo_phos PF03372.23 EGB07285.1 - 9.5e-06 25.3 0.1 1.3e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4033 PF13225.6 EGB07286.1 - 4.6e-33 113.1 0.0 7.6e-33 112.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) DUF563 PF04577.14 EGB07287.1 - 6.8e-15 55.8 0.1 2.2e-14 54.1 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Pyr_redox_2 PF07992.14 EGB07288.1 - 3.1e-35 121.9 0.5 3.7e-35 121.6 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB07288.1 - 7.3e-20 71.4 0.0 7.6e-13 48.4 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB07288.1 - 3.6e-11 42.8 4.7 1.3e-07 31.1 0.3 3.5 2 1 2 4 4 4 3 FAD binding domain HI0933_like PF03486.14 EGB07288.1 - 1.9e-08 33.5 0.1 2.3e-05 23.3 0.1 2.7 4 0 0 4 4 4 2 HI0933-like protein Pyr_redox PF00070.27 EGB07288.1 - 3.9e-08 33.7 0.5 0.015 15.9 0.1 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGB07288.1 - 6.1e-08 32.4 0.2 1.1e-07 31.5 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EGB07288.1 - 1.1e-07 31.8 0.5 7.5e-06 25.8 0.4 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGB07288.1 - 4.7e-07 29.2 0.3 0.00064 18.9 0.2 2.1 1 1 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 EGB07288.1 - 5.8e-07 29.0 0.1 1.6e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGB07288.1 - 1.4e-06 27.7 0.3 0.00016 20.9 0.3 2.9 2 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGB07288.1 - 2e-06 27.9 0.0 4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGB07288.1 - 0.00024 20.5 0.1 0.00044 19.6 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EGB07288.1 - 0.037 14.0 0.2 4 7.4 0.1 2.5 1 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EGB07288.1 - 0.16 12.5 0.1 3.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding HOOK PF05622.12 EGB07289.1 - 1 7.4 7.1 3 5.9 0.2 2.1 2 0 0 2 2 2 0 HOOK protein Sel1 PF08238.12 EGB07290.1 - 7.1e-85 277.5 73.3 1.9e-08 34.7 0.1 16.2 16 0 0 16 16 16 14 Sel1 repeat zf-MYND PF01753.18 EGB07290.1 - 2.5e-08 33.9 7.9 5.2e-08 32.8 7.9 1.5 1 0 0 1 1 1 1 MYND finger MIT PF04212.18 EGB07290.1 - 0.0013 18.7 20.8 0.46 10.6 0.2 6.2 5 0 0 5 5 5 3 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EGB07290.1 - 0.0028 17.9 3.7 16 6.1 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB07290.1 - 0.008 16.6 15.9 12 6.4 0.0 6.8 5 2 2 7 7 7 2 B12 binding domain PDDEXK_10 PF07788.11 EGB07290.1 - 0.026 14.4 0.8 66 3.5 0.0 4.5 4 0 0 4 4 4 0 PD-(D/E)XK nuclease superfamily 3D PF06725.11 EGB07290.1 - 0.046 13.9 0.8 41 4.4 0.0 4.4 5 1 1 6 6 6 0 3D domain zf-HIT PF04438.16 EGB07290.1 - 0.08 12.8 8.0 0.18 11.7 8.0 1.6 1 0 0 1 1 1 0 HIT zinc finger TPR_8 PF13181.6 EGB07290.1 - 0.12 12.6 21.5 9.8 6.7 0.3 7.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB07290.1 - 0.18 11.7 37.0 0.16 11.8 0.7 9.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB07290.1 - 0.62 10.4 43.3 0.35 11.2 0.8 8.9 8 4 2 10 10 10 0 Tetratricopeptide repeat EF-hand_like PF09279.11 EGB07290.1 - 5.4 7.6 5.3 8.1 7.0 0.1 3.5 5 0 0 5 5 5 0 Phosphoinositide-specific phospholipase C, efhand-like Sel1 PF08238.12 EGB07291.1 - 2.9e-23 81.8 9.2 6.2e-10 39.4 0.0 3.6 3 1 0 3 3 3 3 Sel1 repeat MIT PF04212.18 EGB07291.1 - 0.0039 17.2 2.3 0.0072 16.4 0.6 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EGB07291.1 - 0.14 12.5 7.4 0.099 12.9 1.3 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB07291.1 - 0.21 11.7 5.1 3.8 7.8 0.1 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB07291.1 - 0.37 11.2 1.7 3.1 8.3 0.2 2.6 2 1 1 3 3 3 0 B12 binding domain TPR_8 PF13181.6 EGB07291.1 - 1.6 9.1 7.8 1.4 9.4 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 EGB07292.1 - 3.9e-27 95.0 0.0 6.4e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGB07292.1 - 3.5e-08 33.5 0.0 6.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB07292.1 - 6.3e-06 25.7 1.0 9e-05 22.0 1.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 EGB07292.1 - 6.3e-05 23.3 0.1 0.00024 21.4 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.19 EGB07292.1 - 0.00014 21.6 1.7 0.0014 18.2 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EGB07292.1 - 0.00039 20.4 0.7 0.0062 16.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EGB07292.1 - 0.00088 18.7 0.5 0.0056 16.1 0.5 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RIBIOP_C PF04950.12 EGB07292.1 - 0.021 14.3 2.4 0.075 12.4 0.5 2.1 2 0 0 2 2 2 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PduV-EutP PF10662.9 EGB07292.1 - 0.18 11.5 1.5 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNase_T PF00929.24 EGB07293.1 - 4.2e-24 85.9 0.0 8.6e-24 84.9 0.0 1.4 1 1 0 1 1 1 1 Exonuclease ABATE PF07336.11 EGB07293.1 - 0.0033 18.1 1.7 0.0043 17.7 1.7 1.3 1 0 0 1 1 1 1 Putative stress-induced transcription regulator DUF5051 PF16473.5 EGB07293.1 - 0.13 12.3 0.0 0.37 10.7 0.0 1.8 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like Sulfotransfer_3 PF13469.6 EGB07294.1 - 8e-09 36.2 1.4 0.00055 20.4 0.1 3.2 3 1 0 3 3 3 2 Sulfotransferase family Amino_oxidase PF01593.24 EGB07295.1 - 1.1e-21 77.7 3.7 3.2e-21 76.1 3.7 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB07295.1 - 1.4e-11 44.4 0.4 4e-11 43.0 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGB07295.1 - 1.5e-09 37.1 0.6 0.00035 19.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EGB07295.1 - 1.5e-08 34.3 2.5 0.00022 20.5 0.2 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB07295.1 - 1.1e-07 31.8 10.4 5.4e-06 26.2 10.4 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB07295.1 - 1e-06 28.1 6.5 0.00041 19.6 3.4 2.3 1 1 1 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EGB07295.1 - 6.3e-05 23.5 6.6 0.00033 21.1 1.3 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGB07295.1 - 0.00037 19.9 0.1 0.0006 19.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EGB07295.1 - 0.0008 18.4 3.9 0.11 11.3 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 EGB07295.1 - 0.0011 18.4 5.0 0.0026 17.2 3.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGB07295.1 - 0.0014 17.7 1.1 0.089 11.8 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGB07295.1 - 0.0023 17.2 1.2 0.0023 17.2 1.2 1.5 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 EGB07295.1 - 0.0025 17.2 0.5 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_9 PF13454.6 EGB07295.1 - 0.0032 17.5 1.4 1.6 8.7 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EGB07295.1 - 0.0072 15.5 0.6 0.28 10.2 0.4 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGB07295.1 - 0.09 12.0 0.9 0.14 11.4 0.9 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Citrate_synt PF00285.21 EGB07296.1 - 9.7e-107 357.1 0.0 1.3e-106 356.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cluap1 PF10234.9 EGB07298.1 - 4.2e-102 341.1 16.7 4.2e-102 341.1 16.7 1.4 1 1 1 2 2 2 1 Clusterin-associated protein-1 Lebercilin PF15619.6 EGB07298.1 - 3.2e-05 23.7 20.6 3.2e-05 23.7 20.6 1.7 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EGB07298.1 - 0.1 12.6 11.2 0.14 12.2 3.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) LPP PF04728.13 EGB07298.1 - 0.11 12.9 0.7 0.11 12.9 0.7 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Sec34 PF04136.15 EGB07298.1 - 0.19 11.6 11.5 0.24 11.3 8.3 2.7 1 1 1 2 2 2 0 Sec34-like family Sec2p PF06428.11 EGB07298.1 - 0.44 10.5 13.6 0.27 11.2 3.2 2.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p UPF0242 PF06785.11 EGB07298.1 - 0.48 10.5 22.1 0.061 13.4 8.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4795 PF16043.5 EGB07298.1 - 0.6 9.7 17.6 0.81 9.3 16.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ATG16 PF08614.11 EGB07298.1 - 0.75 10.0 22.1 0.18 12.0 18.0 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Allexi_40kDa PF05549.11 EGB07298.1 - 0.82 9.1 9.2 0.14 11.7 4.4 2.0 1 1 2 3 3 3 0 Allexivirus 40kDa protein Atg14 PF10186.9 EGB07298.1 - 0.89 8.6 13.1 0.79 8.8 12.1 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EGB07298.1 - 1.1 8.4 15.6 2.7 7.2 7.7 2.4 1 1 1 2 2 2 0 TMPIT-like protein Tropomyosin_1 PF12718.7 EGB07298.1 - 1.2 9.3 24.7 0.15 12.2 19.6 2.1 1 1 0 1 1 1 0 Tropomyosin like Lectin_N PF03954.14 EGB07298.1 - 1.5 8.6 10.5 0.22 11.2 3.8 2.6 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF3450 PF11932.8 EGB07298.1 - 2.6 7.3 21.9 0.55 9.5 3.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Bacillus_HBL PF05791.11 EGB07298.1 - 3 7.7 11.7 0.78 9.5 2.7 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CLZ PF16526.5 EGB07298.1 - 3.7 8.0 22.1 0.25 11.7 1.5 4.3 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 EGB07298.1 - 3.7 6.8 16.4 17 4.6 16.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2951 PF11166.8 EGB07298.1 - 3.8 7.8 15.6 0.4 10.9 5.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) FliD_C PF07195.12 EGB07298.1 - 4.6 6.6 16.5 0.16 11.4 5.3 2.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.10 EGB07298.1 - 5.3 7.2 18.9 1.5e+02 2.5 15.9 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 EGB07298.1 - 7.8 6.0 23.1 3.3 7.2 16.8 2.6 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 EGB07298.1 - 9.6 5.0 25.2 0.1 11.5 12.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 EGB07298.1 - 9.7 6.5 7.0 3.1 8.1 1.5 2.9 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) Sulfatase PF00884.23 EGB07299.1 - 1.1e-49 169.5 0.1 1.5e-49 169.1 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Esterase PF00756.20 EGB07300.1 - 7.9e-29 101.0 0.0 9e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGB07300.1 - 9.8e-06 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGB07300.1 - 0.00032 21.4 10.6 0.0013 19.3 10.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB07300.1 - 0.0012 18.2 0.1 0.0076 15.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Amidase_5 PF05382.13 EGB07300.1 - 0.0069 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase DLH PF01738.18 EGB07300.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EGB07300.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Aminotran_4 PF01063.19 EGB07301.1 - 3.5e-23 82.6 0.0 4.2e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_trans_1_4 PF13692.6 EGB07301.1 - 0.14 12.6 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 UPF0300 PF08594.10 EGB07301.1 - 0.29 10.4 0.0 0.43 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) Mito_carr PF00153.27 EGB07302.1 - 6.9e-32 109.2 0.1 3.2e-18 65.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sep15_SelM PF08806.11 EGB07303.1 - 1.1e-25 89.6 0.0 1.3e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Sep15/SelM redox domain Epimerase PF01370.21 EGB07304.1 - 8.1e-10 38.6 0.0 1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB07304.1 - 3.6e-08 33.2 0.0 4.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGB07304.1 - 6.3e-07 29.2 0.1 8.2e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGB07304.1 - 1.8e-06 28.0 0.1 3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGB07304.1 - 8.3e-06 25.1 0.3 9.6e-06 24.9 0.3 1.1 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EGB07304.1 - 4e-05 22.8 0.0 4.7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGB07304.1 - 0.0048 16.0 0.1 0.0059 15.7 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EGB07304.1 - 0.0055 16.2 0.2 0.0066 15.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 EGB07304.1 - 0.038 14.4 0.0 0.046 14.2 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EGB07304.1 - 0.06 13.3 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 KR domain PepSY_2 PF13670.6 EGB07304.1 - 0.087 12.8 0.6 0.14 12.2 0.6 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Polysacc_synt_2 PF02719.15 EGB07304.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_3 PF00933.21 EGB07305.1 - 6.2e-29 101.4 0.0 6.8e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Chloroa_b-bind PF00504.21 EGB07306.1 - 4.8e-40 137.7 0.1 6e-40 137.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Thioredoxin PF00085.20 EGB07307.1 - 1.5e-11 44.2 0.0 2.1e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EGB07307.1 - 0.00012 21.1 0.0 0.00014 20.9 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 EGB07307.1 - 0.0022 18.4 0.5 0.0078 16.7 0.5 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EGB07307.1 - 0.0026 17.6 0.4 0.0035 17.2 0.0 1.4 2 0 0 2 2 2 1 F plasmid transfer operon protein Chloroa_b-bind PF00504.21 EGB07308.1 - 2.6e-25 89.8 0.1 3.4e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RNase_T PF00929.24 EGB07309.1 - 0.0045 17.5 0.0 0.0082 16.7 0.0 1.6 1 1 0 1 1 1 1 Exonuclease DUF3670 PF12419.8 EGB07309.1 - 0.093 12.6 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 SNF2 Helicase protein DNA_pol_A_exo1 PF01612.20 EGB07309.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease MAT1 PF06391.13 EGB07310.1 - 3.3e-19 69.5 0.0 4.6e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.25 EGB07310.1 - 3.4e-06 26.8 3.8 6.1e-06 26.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB07310.1 - 0.00012 22.4 5.8 0.00024 21.3 5.8 1.5 1 1 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 EGB07310.1 - 0.00028 20.7 1.5 0.00052 19.8 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EGB07310.1 - 0.00036 20.6 0.8 0.00085 19.4 0.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGB07310.1 - 0.00074 19.3 1.3 0.00074 19.3 1.3 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB07310.1 - 0.0027 17.7 3.7 0.0046 17.0 3.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGB07310.1 - 0.0037 17.5 2.0 0.0063 16.8 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 EGB07310.1 - 0.051 13.5 8.7 0.12 12.3 8.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGB07310.1 - 0.086 12.7 9.1 0.56 10.1 9.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB07310.1 - 0.1 12.6 9.0 0.32 11.0 9.2 1.8 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGB07310.1 - 0.98 9.1 6.0 2.6 7.7 6.0 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 EGB07310.1 - 1.4 9.2 6.7 12 6.2 0.0 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF1348 PF07080.11 EGB07311.1 - 1.1e-62 209.8 3.8 1.2e-62 209.6 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EGB07311.1 - 1.8e-08 34.9 2.9 2.6e-08 34.4 2.9 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGB07311.1 - 0.051 14.0 0.6 0.069 13.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF1445 PF07286.12 EGB07312.1 - 3.3e-63 211.9 0.0 4.2e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) UCH PF00443.29 EGB07313.1 - 4.2e-45 154.3 0.0 5.4e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.25 EGB07313.1 - 1.1e-14 54.4 0.0 2.7e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB07313.1 - 1.5e-11 44.3 0.3 3.5e-11 43.1 0.3 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUSP PF06337.12 EGB07313.1 - 3.6e-09 37.1 0.0 5.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 DUSP domain zf-MYND PF01753.18 EGB07313.1 - 6.1e-08 32.6 10.4 2e-07 30.9 10.4 2.0 1 0 0 1 1 1 1 MYND finger PQQ_3 PF13570.6 EGB07313.1 - 0.01 16.3 12.2 0.15 12.6 0.0 6.2 6 0 0 6 6 6 0 PQQ-like domain zf-C6H2 PF15801.5 EGB07313.1 - 0.42 10.9 3.5 3.7 7.9 1.2 2.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Glycos_transf_2 PF00535.26 EGB07314.1 - 5.3e-10 39.4 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_25 PF01755.17 EGB07314.1 - 2.5e-05 24.2 0.0 0.00015 21.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_3 PF13641.6 EGB07314.1 - 0.038 13.9 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase like family 2 NPCBM_assoc PF10633.9 EGB07314.1 - 0.077 13.3 1.3 18 5.7 0.5 2.8 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Asp_Arg_Hydrox PF05118.15 EGB07315.1 - 1.1e-16 61.0 1.1 2.9e-16 59.7 1.1 1.7 1 1 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase PCIF1_WW PF12237.8 EGB07316.1 - 3.4e-31 108.2 0.1 5.9e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Lipase_3 PF01764.25 EGB07316.1 - 7.5e-17 61.5 0.0 4.2e-08 33.2 0.0 2.7 2 1 0 2 2 2 2 Lipase (class 3) Aa_trans PF01490.18 EGB07316.1 - 4e-16 58.7 18.4 6.2e-15 54.8 18.4 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SpoU_methylase PF00588.19 EGB07316.1 - 2.7e-13 50.3 0.0 5.9e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family C2 PF00168.30 EGB07316.1 - 7.7e-07 29.4 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain CS PF04969.16 EGB07317.1 - 0.00026 21.9 0.0 0.00049 21.1 0.0 1.5 1 0 0 1 1 1 1 CS domain ubiquitin PF00240.23 EGB07319.1 - 1.2e-07 31.4 0.2 2e-07 30.6 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGB07319.1 - 0.00017 22.0 0.1 0.00089 19.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EGB07319.1 - 0.054 13.3 0.2 0.19 11.6 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PX PF00787.24 EGB07320.1 - 5.6e-10 39.2 0.0 1.4e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 PX domain DUF1320 PF07030.12 EGB07320.1 - 0.055 13.6 0.4 0.13 12.4 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Methyltransf_11 PF08241.12 EGB07321.1 - 2.3e-12 47.4 0.0 4.1e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB07321.1 - 2.2e-10 40.5 0.0 4e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB07321.1 - 8.8e-10 39.2 0.2 1.9e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB07321.1 - 1.4e-05 25.0 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB07321.1 - 0.001 19.7 0.0 0.004 17.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain USP7_C2 PF14533.6 EGB07321.1 - 0.06 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal UQ_con PF00179.26 EGB07322.1 - 7.7e-28 96.9 0.0 9.5e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGB07322.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EGB07322.1 - 0.17 12.2 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain Got1 PF04178.12 EGB07323.1 - 3.9e-20 72.3 11.3 4.6e-20 72.1 11.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family EpsG PF14897.6 EGB07323.1 - 0.011 15.1 8.1 0.018 14.4 8.1 1.3 1 1 0 1 1 1 0 EpsG family HMG_box PF00505.19 EGB07324.1 - 2.1e-22 79.3 0.5 2.3e-22 79.2 0.5 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB07324.1 - 1.9e-15 57.2 0.8 2.2e-15 57.0 0.8 1.0 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EGB07324.1 - 0.0035 17.9 0.0 0.005 17.4 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 PT PF04886.12 EGB07325.1 - 1e-07 31.3 443.0 0.00014 21.4 12.2 24.6 7 3 14 21 21 21 10 PT repeat zf-FCS PF06467.14 EGB07325.1 - 0.34 10.9 3.6 0.99 9.4 3.6 1.8 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Glyco_transf_90 PF05686.12 EGB07326.1 - 4.9e-06 25.7 0.0 0.014 14.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 SpoU_methylase PF00588.19 EGB07327.1 - 3.1e-23 82.5 0.0 4.3e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGB07327.1 - 0.028 14.7 0.0 0.17 12.2 0.0 2.1 1 1 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Tyrosinase PF00264.20 EGB07328.1 - 3.2e-12 47.2 0.2 1.1e-10 42.2 0.2 2.2 2 0 0 2 2 2 1 Common central domain of tyrosinase MHC_I_3 PF16497.5 EGB07328.1 - 0.019 14.4 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 MHC-I family domain DUF547 PF04784.14 EGB07329.1 - 2.2e-18 66.5 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Gelsolin PF00626.22 EGB07331.1 - 7.6e-10 38.6 0.0 0.012 15.5 0.0 4.7 4 0 0 4 4 4 2 Gelsolin repeat Cofilin_ADF PF00241.20 EGB07331.1 - 1.6e-05 24.7 0.0 8.5e-05 22.3 0.0 2.2 3 0 0 3 3 3 1 Cofilin/tropomyosin-type actin-binding protein DUF3640 PF12342.8 EGB07332.1 - 0.1 12.4 8.8 16 5.3 0.4 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3640) Cornifin PF02389.15 EGB07332.1 - 0.2 11.8 0.0 0.21 11.8 0.0 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family JmjC PF02373.22 EGB07333.1 - 6.8e-09 36.2 0.5 1.1e-07 32.3 0.5 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGB07333.1 - 1.3e-06 28.3 0.0 1.6e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Lipase_3 PF01764.25 EGB07334.1 - 8.7e-23 80.8 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGB07334.1 - 0.0016 18.1 0.1 0.0038 16.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGB07334.1 - 0.041 13.1 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB07335.1 - 9.1e-18 64.8 0.1 1.1e-17 64.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB07335.1 - 3.9e-11 44.0 8.5 4.7e-11 43.7 8.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB07335.1 - 3.9e-10 39.4 0.3 5.3e-10 39.0 0.3 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGB07335.1 - 1.5e-05 24.8 0.1 1.9e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 EGB07335.1 - 0.0002 20.1 0.0 0.00027 19.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 EGB07335.1 - 0.00055 20.1 0.1 0.00083 19.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGB07335.1 - 0.0018 18.0 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 EGB07335.1 - 0.0031 17.3 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EGB07335.1 - 0.0042 16.6 2.1 0.0042 16.6 2.1 1.8 1 1 1 2 2 2 1 Esterase PHB depolymerase DUF915 PF06028.11 EGB07335.1 - 0.069 12.5 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 EGB07335.1 - 0.14 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ADH_zinc_N PF00107.26 EGB07336.1 - 4e-16 59.2 0.7 6.9e-16 58.4 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGB07336.1 - 8.5e-12 46.3 0.1 1.4e-11 45.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGB07336.1 - 3e-09 36.7 0.1 5.9e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TPR_16 PF13432.6 EGB07337.1 - 6.2e-06 26.8 4.8 6.2e-06 26.8 4.8 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB07337.1 - 5e-05 23.5 9.5 0.21 11.9 0.1 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07337.1 - 8.6e-05 22.4 13.8 0.13 12.4 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB07337.1 - 0.00013 21.5 1.0 0.00027 20.5 1.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 EGB07337.1 - 0.0004 20.1 6.3 1.4 8.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07337.1 - 0.0012 19.3 11.5 0.022 15.2 2.8 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB07337.1 - 0.013 16.2 12.4 0.8 10.7 1.2 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB07337.1 - 0.046 14.1 0.4 0.16 12.4 0.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07337.1 - 0.14 12.4 3.7 7.2 7.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB07337.1 - 0.59 10.4 6.9 0.17 12.1 2.2 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGB07337.1 - 0.63 10.0 10.4 1.5 8.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PX PF00787.24 EGB07339.1 - 7.8e-08 32.3 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 PX domain SecA_DEAD PF07517.14 EGB07340.1 - 6.2e-85 285.0 0.0 9.5e-85 284.4 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 EGB07340.1 - 3.1e-37 128.6 0.0 4.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 EGB07340.1 - 4.1e-21 75.7 0.0 1.1e-20 74.3 0.0 1.8 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 EGB07340.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase PT PF04886.12 EGB07341.1 - 9.2e-05 21.9 57.0 0.0057 16.2 26.8 4.5 2 1 1 3 3 3 2 PT repeat KAR9 PF08580.10 EGB07341.1 - 0.88 8.0 7.2 0.87 8.1 7.2 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_S9 PF00326.21 EGB07342.1 - 4e-29 101.6 0.0 6.9e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Acetyltransf_1 PF00583.25 EGB07342.1 - 1.4e-11 44.7 0.1 2.8e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGB07342.1 - 6.7e-10 39.0 0.1 1.3e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB07342.1 - 1.3e-08 35.2 0.0 3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_S9_N PF02897.15 EGB07342.1 - 2.2e-06 26.8 0.0 5.4e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain FR47 PF08445.10 EGB07342.1 - 0.00018 21.4 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGB07342.1 - 0.00034 20.7 0.0 0.001 19.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGB07342.1 - 0.067 13.2 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase GNAT_acetyltran PF12746.7 EGB07342.1 - 0.16 11.5 0.3 0.26 10.8 0.3 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Ank_2 PF12796.7 EGB07343.1 - 3.5e-28 98.0 25.6 9.1e-06 26.2 0.1 9.7 6 2 1 9 9 9 6 Ankyrin repeats (3 copies) Pkinase PF00069.25 EGB07343.1 - 2.9e-19 69.5 0.0 4.2e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 EGB07343.1 - 1.3e-18 67.1 22.6 7.4e-05 23.2 0.2 9.3 9 2 1 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB07343.1 - 1.2e-12 46.8 27.0 0.0029 17.9 0.0 13.2 12 0 0 12 12 12 1 Ankyrin repeat Ank PF00023.30 EGB07343.1 - 6.3e-12 45.4 28.9 0.074 13.5 0.0 11.2 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 EGB07343.1 - 3.5e-09 36.7 35.7 0.053 13.9 0.0 10.3 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 EGB07343.1 - 2.3e-08 33.6 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sulf_transp PF04143.14 EGB07343.1 - 0.0004 20.0 13.2 0.0011 18.6 13.2 1.7 1 0 0 1 1 1 1 Sulphur transport EF-hand_1 PF00036.32 EGB07344.1 - 2.2e-20 70.6 13.9 8.9e-06 24.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB07344.1 - 5e-18 63.4 11.3 1.3e-06 27.9 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGB07344.1 - 4e-17 62.4 7.9 2.9e-08 34.1 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB07344.1 - 8.9e-14 51.1 13.5 1.6e-05 24.7 1.8 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB07344.1 - 1.8e-13 49.3 14.3 0.00024 20.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGB07344.1 - 0.021 15.2 0.8 1.6 9.1 0.1 2.9 2 2 0 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 EGB07344.1 - 0.095 13.1 0.2 3.5 8.0 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EGB07345.1 - 3.7e-21 73.0 0.2 7.3e-05 22.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB07345.1 - 3.1e-20 72.4 0.3 1.1e-09 38.6 0.6 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGB07345.1 - 3.6e-17 60.8 0.3 0.0048 16.7 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB07345.1 - 3.4e-15 55.6 0.1 8.3e-10 38.4 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB07345.1 - 6e-09 35.0 2.3 0.0098 15.4 0.0 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 EGB07345.1 - 0.0025 18.1 0.0 1.5 9.1 0.0 2.3 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGB07345.1 - 0.0057 16.6 0.2 5.8 6.9 0.0 3.5 1 1 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGB07345.1 - 0.052 13.4 0.1 0.32 10.9 0.0 2.4 2 1 1 3 3 3 0 EF hand Aldo_ket_red PF00248.21 EGB07346.1 - 1.3e-44 152.6 0.0 6e-43 147.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family zf-C3HC4_3 PF13920.6 EGB07348.1 - 1.7e-10 40.6 11.6 1.9e-10 40.4 11.6 1.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB07348.1 - 0.02 14.7 11.1 0.027 14.3 11.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGB07348.1 - 0.046 13.8 8.8 0.079 13.0 8.8 1.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EGB07348.1 - 0.34 10.9 12.1 2.2 8.3 12.4 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGB07348.1 - 0.84 9.4 11.8 5.8 6.8 7.2 3.1 2 1 0 2 2 2 0 RING-like zinc finger SBP_bac_3 PF00497.20 EGB07349.1 - 9.7e-13 48.1 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Methyltransf_11 PF08241.12 EGB07350.1 - 9.9e-11 42.1 0.0 2.7e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB07350.1 - 4.9e-06 27.2 0.0 1.4e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB07350.1 - 0.00011 22.0 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB07350.1 - 0.00073 20.2 0.0 0.0017 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EGB07350.1 - 0.00091 17.9 0.0 0.0015 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 EGB07350.1 - 0.0027 17.6 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGB07350.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EGB07350.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Heme_oxygenase PF01126.20 EGB07352.1 - 4.7e-52 176.8 0.0 5.6e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Heme oxygenase TPR_14 PF13428.6 EGB07353.1 - 0.064 14.1 10.9 11 7.1 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 EGB07354.1 - 2.6e-39 135.0 0.0 2.9e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MMR_HSR1 PF01926.23 EGB07355.1 - 3.9e-15 55.9 0.0 6.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGB07355.1 - 0.0006 19.9 0.0 0.0026 17.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.16 EGB07355.1 - 0.0082 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGB07355.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 EGB07355.1 - 0.022 14.3 0.0 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Guanylate_kin PF00625.21 EGB07355.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_16 PF13191.6 EGB07355.1 - 0.15 12.4 0.1 0.15 12.4 0.1 3.3 1 1 1 2 2 2 0 AAA ATPase domain Roc PF08477.13 EGB07355.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DSBA PF01323.20 EGB07356.1 - 7.6e-17 61.7 0.0 1.3e-16 60.9 0.0 1.4 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 EGB07356.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.6 EGB07356.1 - 0.082 13.4 0.0 4.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain DUF676 PF05057.14 EGB07357.1 - 1.2e-25 90.3 0.0 3e-17 62.9 0.0 3.0 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGB07357.1 - 0.044 13.6 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Rhomboid PF01694.22 EGB07358.1 - 1.5e-21 77.0 16.5 2e-21 76.5 16.5 1.2 1 0 0 1 1 1 1 Rhomboid family Transglut_core PF01841.19 EGB07359.1 - 1.4e-11 44.9 0.8 2.1e-11 44.3 0.8 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily FTCD_N PF07837.12 EGB07360.1 - 1.5e-28 99.8 1.2 3.6e-28 98.5 0.3 1.8 2 0 0 2 2 2 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 EGB07360.1 - 4.2e-07 30.1 0.0 6.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain RHH_5 PF07878.11 EGB07360.1 - 0.057 13.3 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HMGL-like PF00682.19 EGB07361.1 - 5.2e-43 147.5 0.7 8e-43 146.9 0.7 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EGB07361.1 - 1.8e-21 76.4 0.3 5e-21 75.0 0.3 1.8 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF676 PF05057.14 EGB07362.1 - 1.6e-05 24.5 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) CPSase_L_D2 PF02786.17 EGB07363.1 - 3.5e-65 219.5 0.0 6.2e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGB07363.1 - 6.7e-41 139.3 0.6 1.6e-40 138.1 0.3 1.9 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGB07363.1 - 2.9e-32 111.0 0.0 1.2e-31 109.0 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Elong-fact-P_C PF09285.11 EGB07363.1 - 1.5e-21 75.9 0.1 4.8e-21 74.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor P, C-terminal Biotin_lipoyl PF00364.22 EGB07363.1 - 7.8e-15 54.5 0.8 2.6e-14 52.8 0.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme EFP PF01132.20 EGB07363.1 - 1.5e-12 47.3 0.2 3.7e-12 46.1 0.2 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 EGB07363.1 - 6.1e-09 35.8 0.2 1.5e-08 34.5 0.2 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain ATP-grasp PF02222.22 EGB07363.1 - 8.3e-09 35.2 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGB07363.1 - 0.0022 17.6 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EGB07363.1 - 0.0066 16.3 0.0 0.053 13.3 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_5 PF13549.6 EGB07363.1 - 0.019 14.4 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain PCC_BT PF18140.1 EGB07363.1 - 0.027 14.8 0.0 0.12 12.7 0.0 2.2 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain ATPgrasp_ST PF14397.6 EGB07363.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Aa_trans PF01490.18 EGB07364.1 - 3.5e-05 22.7 6.4 0.00014 20.8 0.9 2.3 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Thioredoxin PF00085.20 EGB07365.1 - 5.3e-23 81.0 0.0 6.2e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB07365.1 - 2e-05 25.0 0.2 4.1e-05 24.0 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGB07365.1 - 0.00018 21.4 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EGB07365.1 - 0.00024 20.5 0.1 0.00025 20.5 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGB07365.1 - 0.00064 19.9 0.2 0.0019 18.3 0.2 1.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EGB07365.1 - 0.00067 19.9 0.0 0.00072 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EGB07365.1 - 0.0043 17.2 0.2 0.0072 16.5 0.2 1.4 1 1 0 1 1 1 1 Glutaredoxin T4_deiodinase PF00837.17 EGB07365.1 - 0.036 13.4 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_3 PF13192.6 EGB07365.1 - 0.054 13.6 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 EGB07365.1 - 0.055 13.2 0.1 0.068 12.9 0.1 1.2 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_5 PF13743.6 EGB07365.1 - 0.081 12.6 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin HyaE PF07449.11 EGB07365.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Bac_rhamnosid6H PF17389.2 EGB07366.1 - 2.4e-13 50.1 1.3 4.4e-13 49.2 1.3 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EGB07366.1 - 1.9e-07 30.8 0.2 4.5e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid_N PF08531.10 EGB07366.1 - 0.00074 19.4 0.8 0.002 18.0 0.8 1.7 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Mito_carr PF00153.27 EGB07367.1 - 9.6e-30 102.4 4.0 3.4e-14 52.5 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein ABC_tran PF00005.27 EGB07368.1 - 2.5e-41 141.4 0.0 1.4e-22 80.7 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB07368.1 - 7e-20 72.0 3.0 6.6e-06 26.1 0.0 4.4 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB07368.1 - 5.6e-10 39.0 0.3 0.098 12.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB07368.1 - 2.2e-08 33.7 0.0 0.0021 17.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB07368.1 - 1.5e-07 31.5 0.1 0.0078 16.1 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGB07368.1 - 3.1e-07 30.5 0.1 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGB07368.1 - 2.6e-06 28.1 0.0 0.072 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGB07368.1 - 3.8e-06 27.4 12.6 0.03 14.7 0.2 3.5 2 1 1 3 3 3 2 AAA ATPase domain MeaB PF03308.16 EGB07368.1 - 1.9e-05 23.8 0.9 0.00038 19.5 0.0 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EGB07368.1 - 5.2e-05 23.1 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGB07368.1 - 7.7e-05 22.9 0.9 0.4 10.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain ATP-synt_ab PF00006.25 EGB07368.1 - 8.7e-05 22.3 0.3 0.051 13.2 0.1 2.5 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 EGB07368.1 - 0.00017 20.8 1.2 0.017 14.3 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) NACHT PF05729.12 EGB07368.1 - 0.0002 21.3 4.2 0.16 11.9 0.1 2.7 3 0 0 3 3 2 2 NACHT domain cobW PF02492.19 EGB07368.1 - 0.00055 19.6 0.2 0.033 13.8 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EGB07368.1 - 0.0011 18.9 0.7 0.44 10.4 0.1 2.8 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGB07368.1 - 0.0013 19.1 1.5 0.79 9.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EGB07368.1 - 0.0013 19.2 3.3 2.6 8.5 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB07368.1 - 0.0014 19.0 0.3 2.8 8.4 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_27 PF13514.6 EGB07368.1 - 0.0015 18.2 2.2 0.61 9.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 EGB07368.1 - 0.0016 18.5 3.3 0.61 10.1 0.1 2.8 3 0 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EGB07368.1 - 0.0019 17.8 0.2 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran_Xtn PF12848.7 EGB07368.1 - 0.0028 17.6 0.4 0.0058 16.6 0.4 1.5 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 EGB07368.1 - 0.0029 17.4 13.6 0.0043 16.8 0.1 3.6 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 EGB07368.1 - 0.0044 17.2 4.2 0.12 12.5 0.1 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain IstB_IS21 PF01695.17 EGB07368.1 - 0.0046 16.7 4.0 0.19 11.4 0.3 2.9 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGB07368.1 - 0.0055 17.0 6.4 0.72 10.1 0.2 3.8 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EGB07368.1 - 0.0067 15.6 0.8 0.61 9.2 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain AAA_18 PF13238.6 EGB07368.1 - 0.0069 16.9 0.1 0.54 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 EGB07368.1 - 0.014 15.3 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 EGB07368.1 - 0.014 15.4 0.1 4.8 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGB07368.1 - 0.018 14.3 2.7 0.49 9.7 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin DAP3 PF10236.9 EGB07368.1 - 0.019 14.2 1.8 1.3 8.1 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 EGB07368.1 - 0.019 14.5 0.1 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGB07368.1 - 0.021 14.6 0.0 4.9 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EGB07368.1 - 0.023 14.0 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 EGB07368.1 - 0.028 13.8 0.1 0.77 9.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 EGB07368.1 - 0.04 14.1 0.3 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EGB07368.1 - 0.043 13.7 5.2 1.5 8.7 0.1 3.8 5 0 0 5 5 4 0 NTPase FeoB_N PF02421.18 EGB07368.1 - 0.045 13.3 0.1 7 6.2 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EGB07368.1 - 0.057 13.2 1.4 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EGB07368.1 - 0.13 12.0 0.1 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 EGB07368.1 - 0.16 10.6 0.2 5 5.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain CLP1_P PF16575.5 EGB07368.1 - 0.17 11.6 0.2 0.59 9.9 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Viral_helicase1 PF01443.18 EGB07368.1 - 0.24 11.1 3.5 15 5.2 0.9 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 EGB07368.1 - 0.25 10.9 3.1 4.2 7.0 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EGB07368.1 - 0.26 10.8 16.3 0.54 9.8 1.2 4.4 2 2 2 4 4 4 0 AAA domain AAA_19 PF13245.6 EGB07368.1 - 2.7 8.3 5.3 2.7 8.3 0.3 2.9 3 1 0 3 3 3 0 AAA domain DUF3584 PF12128.8 EGB07368.1 - 3 5.2 6.9 3.1 5.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Pkinase PF00069.25 EGB07369.1 - 4.5e-50 170.5 0.0 6e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07369.1 - 1e-32 113.5 0.0 3.3e-23 82.3 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGB07369.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB07369.1 - 0.0034 17.3 0.7 0.0072 16.3 0.7 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB07369.1 - 0.009 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB07369.1 - 0.02 13.9 0.0 0.039 12.9 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 EGB07369.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Peptidase_S41 PF03572.18 EGB07371.1 - 3.8e-27 94.9 0.0 5.6e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 EGB07371.1 - 4.7e-11 42.9 0.1 1.5e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain FAM194 PF14977.6 EGB07371.1 - 1.3e-08 34.5 0.0 2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 FAM194 protein PDZ_6 PF17820.1 EGB07371.1 - 2e-07 30.7 2.6 2.6e-07 30.4 0.4 2.4 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EGB07371.1 - 4.4e-06 26.9 0.0 1.4e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EGB07371.1 - 0.014 15.4 0.0 0.14 12.2 0.0 2.5 3 0 0 3 3 3 0 Tricorn protease PDZ domain zf_CCCH_4 PF18345.1 EGB07372.1 - 3e-07 30.3 3.3 5.1e-07 29.5 3.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGB07372.1 - 1e-06 28.4 1.7 1.7e-06 27.7 1.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger hnRNP_Q_AcD PF18360.1 EGB07372.1 - 4.1e-06 26.7 0.0 7.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain zf-CCCH PF00642.24 EGB07372.1 - 4.7e-05 23.2 1.4 8.6e-05 22.4 1.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EGB07372.1 - 0.00075 19.9 2.2 0.0014 19.0 2.2 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Sulfate_transp PF00916.20 EGB07373.1 - 7.1e-96 321.2 10.3 9.6e-96 320.8 10.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGB07373.1 - 5e-22 77.7 0.0 1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGB07373.1 - 0.0086 16.5 3.7 0.0086 16.5 3.7 2.7 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EGB07373.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 STAS domain XPC-binding PF09280.11 EGB07374.1 - 1.4e-20 72.7 3.0 2.3e-20 72.1 3.0 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EGB07374.1 - 3e-17 62.2 5.8 1.3e-09 37.8 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EGB07374.1 - 1.6e-14 53.4 0.0 2.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EGB07374.1 - 0.001 19.6 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGB07374.1 - 0.0077 16.6 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EGB07374.1 - 0.026 14.3 0.0 0.076 12.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGB07374.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MSA-2c PF12238.8 EGB07374.1 - 4.3 7.3 11.6 7 6.6 11.6 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Peptidase_M32 PF02074.15 EGB07375.1 - 9e-151 502.9 0.0 1e-150 502.8 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase GYF PF02213.16 EGB07376.1 - 2e-19 69.0 1.8 2.5e-19 68.7 1.8 1.1 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EGB07376.1 - 5e-06 26.2 0.2 5.8e-06 26.0 0.2 1.1 1 0 0 1 1 1 1 GYF domain 2 MatE PF01554.18 EGB07377.1 - 1.5e-07 31.2 7.6 1.5e-07 31.2 7.6 2.7 2 2 0 2 2 2 1 MatE Glyco_trans_1_4 PF13692.6 EGB07378.1 - 2.4e-06 28.0 0.1 0.00023 21.6 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 TPR_11 PF13414.6 EGB07378.1 - 0.00053 19.6 2.3 0.062 13.0 0.1 2.7 2 0 0 2 2 2 2 TPR repeat Glycos_transf_1 PF00534.20 EGB07378.1 - 0.00069 19.2 0.0 0.89 9.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGB07378.1 - 0.0025 18.2 0.0 0.01 16.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 TPR_17 PF13431.6 EGB07378.1 - 0.0026 18.0 0.1 0.027 14.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07378.1 - 0.12 12.6 9.0 0.75 10.1 0.5 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07378.1 - 0.15 12.6 7.4 3.8 8.1 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB07378.1 - 0.54 10.2 3.7 19 5.3 0.6 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Cir_N PF10197.9 EGB07379.1 - 5.4e-11 42.5 6.2 5.4e-11 42.5 6.2 2.6 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR UPF0029 PF01205.19 EGB07380.1 - 2.8e-21 75.8 0.0 3.2e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Pro_isomerase PF00160.21 EGB07381.1 - 3.8e-45 154.0 0.0 4.2e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DHHC PF01529.20 EGB07382.1 - 1.4e-17 64.0 10.2 2.5e-17 63.2 10.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase WW PF00397.26 EGB07382.1 - 8.3e-10 38.6 0.1 1.5e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 WW domain TTL PF03133.15 EGB07383.1 - 9.2e-36 123.5 0.0 1e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EGB07383.1 - 0.00027 20.3 0.0 0.00064 19.1 0.0 1.6 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EGB07383.1 - 0.0066 15.7 0.0 0.52 9.5 0.0 2.7 3 0 0 3 3 3 1 YheC/D like ATP-grasp Unstab_antitox PF09720.10 EGB07383.1 - 0.093 12.8 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Putative addiction module component TPT PF03151.16 EGB07384.1 - 4.7e-70 236.2 10.4 5.8e-70 235.9 10.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB07384.1 - 4.8e-10 39.7 22.3 3.7e-05 23.9 7.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Tab2_like PF06485.11 EGB07385.1 - 8.6e-74 248.4 0.0 9.9e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 Carb_kinase PF01256.17 EGB07386.1 - 4.8e-38 131.0 0.0 6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EGB07386.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family PEP-utilizers PF00391.23 EGB07386.1 - 0.17 11.6 0.9 9.9 6.0 0.0 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain His_Phos_1 PF00300.22 EGB07387.1 - 1.4e-34 119.5 3.3 3.8e-26 92.0 1.7 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ank_4 PF13637.6 EGB07388.1 - 1.8e-16 60.2 0.1 1.7e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB07388.1 - 4.1e-16 59.3 0.1 1.8e-08 34.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB07388.1 - 3.5e-15 55.9 1.5 2.9e-09 37.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB07388.1 - 5e-15 54.1 0.5 0.00046 20.4 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGB07388.1 - 3.9e-14 52.4 0.6 0.0051 17.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat SET PF00856.28 EGB07389.1 - 1.5e-05 25.5 0.4 0.02 15.3 0.0 3.6 2 1 0 2 2 2 1 SET domain Tudor_3 PF18115.1 EGB07389.1 - 0.15 11.9 0.2 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Ammonium_transp PF00909.21 EGB07390.1 - 4e-98 328.7 32.4 4.9e-98 328.4 32.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.25 EGB07391.1 - 7e-45 153.4 0.0 8.4e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07391.1 - 1.2e-38 132.9 0.0 1.3e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB07391.1 - 0.00011 22.2 0.3 0.0002 21.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB07391.1 - 0.00072 18.4 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGB07391.1 - 0.035 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EGB07391.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain adh_short PF00106.25 EGB07392.1 - 1e-39 136.0 0.5 2e-39 135.1 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB07392.1 - 2.5e-39 135.2 1.8 2.5e-39 135.2 1.8 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB07392.1 - 1.2e-08 35.1 0.8 1.2e-08 35.1 0.8 2.6 2 1 0 2 2 2 1 KR domain DUF1776 PF08643.10 EGB07392.1 - 0.0087 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sulfatase PF00884.23 EGB07393.1 - 2.9e-43 148.4 0.0 3.6e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EGB07393.1 - 3.6e-05 22.6 0.0 5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 EGB07393.1 - 0.002 18.3 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 EGB07393.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 EGB07393.1 - 0.032 14.2 0.0 4.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF3198 PF11433.8 EGB07394.1 - 0.069 13.1 2.1 11 6.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) NCA2 PF08637.10 EGB07394.1 - 0.24 10.5 9.5 0.29 10.3 0.1 2.3 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 DUF4618 PF15397.6 EGB07394.1 - 2.5 7.4 15.3 0.58 9.5 8.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Peptidase_S64 PF08192.11 EGB07394.1 - 3.3 6.1 7.9 4.2 5.7 7.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3776 PF12618.8 EGB07394.1 - 5.9 7.5 6.3 22 5.7 1.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3776) DUF3783 PF12646.7 EGB07394.1 - 6.9 6.7 10.1 21 5.2 1.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) WD40 PF00400.32 EGB07395.1 - 2.4e-12 47.1 2.3 0.00025 21.8 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat VPS28 PF03997.12 EGB07396.1 - 4.7e-59 199.2 0.0 5.4e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Methyltransf_25 PF13649.6 EGB07397.1 - 3.2e-13 50.2 2.5 1.1e-08 35.6 0.2 3.0 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGB07397.1 - 1.2e-12 48.3 1.3 9.1e-10 39.1 0.2 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGB07397.1 - 3.4e-09 37.3 0.0 1.6e-05 25.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGB07397.1 - 5.8e-07 29.4 0.0 6.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB07397.1 - 0.019 14.8 0.0 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGB07397.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family TehB PF03848.14 EGB07397.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB ADH_zinc_N PF00107.26 EGB07397.1 - 0.17 11.9 5.7 0.4 10.7 0.1 3.3 2 2 1 3 3 3 0 Zinc-binding dehydrogenase Sulfotransfer_1 PF00685.27 EGB07398.1 - 7.4e-17 61.7 0.0 9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB07398.1 - 0.00056 20.4 0.0 0.0026 18.2 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family Cu-oxidase_3 PF07732.15 EGB07399.1 - 1.2e-29 102.7 0.2 1.3e-29 102.6 0.2 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGB07399.1 - 0.0013 18.5 1.3 0.0088 15.8 1.3 1.9 1 1 0 1 1 1 1 Multicopper oxidase Cons_hypoth698 PF03601.14 EGB07401.1 - 8.3e-49 166.1 21.0 1.1e-48 165.8 21.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 698 Chloroa_b-bind PF00504.21 EGB07402.1 - 2.4e-32 112.7 0.4 3.4e-32 112.2 0.4 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Sulfotransfer_1 PF00685.27 EGB07403.1 - 0.00057 19.5 0.0 0.0011 18.5 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 EGB07403.1 - 0.005 16.8 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family UDG PF03167.19 EGB07404.1 - 0.00013 21.9 0.0 0.00048 20.1 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily ILVD_EDD PF00920.21 EGB07406.1 - 2.1e-170 567.7 5.4 2.4e-170 567.6 5.4 1.0 1 0 0 1 1 1 1 Dehydratase family Dus PF01207.17 EGB07408.1 - 2.3e-52 178.0 0.0 3.3e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 EGB07408.1 - 0.00065 19.7 0.9 0.0014 18.6 0.9 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EGB07408.1 - 0.0011 18.9 2.3 0.0011 18.9 2.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGB07408.1 - 0.0012 19.5 0.5 0.0028 18.3 0.2 1.8 2 0 0 2 2 2 1 Torus domain SIS_2 PF13580.6 EGB07408.1 - 0.016 15.2 0.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 SIS domain zf-CCCH_4 PF18044.1 EGB07408.1 - 0.28 11.0 2.0 0.62 9.9 2.0 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger DUF667 PF05018.13 EGB07409.1 - 1.3e-93 311.9 1.1 1.5e-93 311.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) 6PF2K PF01591.18 EGB07410.1 - 1.6e-50 171.5 0.0 2.2e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Dev_Cell_Death PF10539.9 EGB07410.1 - 1.5e-18 66.9 0.0 2.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Development and cell death domain His_Phos_1 PF00300.22 EGB07410.1 - 0.00012 21.8 0.0 0.00083 19.1 0.0 2.4 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGB07410.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain UCH PF00443.29 EGB07411.1 - 1e-52 179.2 0.0 1.6e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGB07411.1 - 5.6e-12 46.1 0.0 1.1e-11 45.2 0.0 1.5 1 1 0 1 1 1 1 DUSP domain EF-hand_6 PF13405.6 EGB07411.1 - 3.7e-06 26.4 0.0 0.011 15.6 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB07411.1 - 6e-06 26.6 0.0 0.095 13.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair UCH_1 PF13423.6 EGB07411.1 - 1.7e-05 24.6 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_1 PF00036.32 EGB07411.1 - 5.1e-05 22.5 0.0 0.0047 16.4 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGB07411.1 - 0.00013 21.8 0.0 0.045 13.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair SelB-wing_3 PF09107.11 EGB07411.1 - 0.017 14.7 0.1 0.08 12.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF563 PF04577.14 EGB07412.1 - 7.9e-12 45.7 0.0 1.3e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Viral_NABP PF05515.11 EGB07412.1 - 0.1 12.4 0.3 3.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Viral nucleic acid binding Ribosomal_60s PF00428.19 EGB07412.1 - 0.33 11.6 2.0 1.1 9.8 0.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein CAP_N PF01213.19 EGB07412.1 - 1.7 8.1 6.5 3.2 7.2 6.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ion_trans PF00520.31 EGB07413.1 - 1.4e-14 53.9 5.7 2.6e-14 53.0 5.7 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB07413.1 - 1.4e-10 41.0 4.2 2.6e-10 40.1 4.2 1.4 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGB07413.1 - 3.1e-09 36.8 0.0 4.1e-08 33.2 0.0 2.4 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Ribosomal_L12 PF00542.19 EGB07414.1 - 1.9e-25 89.0 9.2 2.1e-25 88.8 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain PG_binding_2 PF08823.11 EGB07414.1 - 0.11 12.9 0.9 0.79 10.1 0.2 2.0 1 1 1 2 2 2 0 Putative peptidoglycan binding domain FKBP_C PF00254.28 EGB07416.1 - 9.7e-19 67.5 0.0 1.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 EGB07416.1 - 1.2e-05 26.2 0.6 2e-05 25.5 0.3 1.4 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2895 PF11444.8 EGB07416.1 - 0.06 12.7 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Peptidase_S41 PF03572.18 EGB07417.1 - 2e-33 115.3 0.0 3.1e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 ELO PF01151.18 EGB07417.1 - 1.3e-27 96.9 3.3 1.8e-27 96.5 3.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PDZ_6 PF17820.1 EGB07417.1 - 2.6e-06 27.2 0.3 7.7e-06 25.7 0.3 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGB07417.1 - 9.9e-06 25.8 0.1 2.1e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGB07417.1 - 0.0069 16.7 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 EGB07418.1 - 1e-61 207.3 0.1 1.2e-61 207.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB07418.1 - 5.9e-36 123.3 0.1 8.4e-36 122.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB07418.1 - 4.8e-14 52.2 0.0 6.4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB07418.1 - 6.9e-07 29.3 0.0 9.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB07418.1 - 9e-06 25.7 1.1 0.017 15.0 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB07418.1 - 0.00036 21.0 0.0 0.00051 20.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 EGB07418.1 - 0.00077 19.1 0.1 0.0037 16.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB07418.1 - 0.00088 18.7 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGB07418.1 - 0.0046 17.2 0.1 0.012 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EGB07418.1 - 0.011 15.2 0.2 0.074 12.6 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 EGB07418.1 - 0.017 14.8 0.0 0.053 13.3 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EGB07418.1 - 0.024 15.2 0.1 0.038 14.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EGB07418.1 - 0.024 14.7 0.0 0.065 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGB07418.1 - 0.028 13.9 0.0 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EGB07418.1 - 0.038 13.7 0.1 0.068 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain PucR PF07905.11 EGB07418.1 - 0.045 14.0 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family MCM PF00493.23 EGB07418.1 - 0.064 12.3 0.0 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain TniB PF05621.11 EGB07418.1 - 0.092 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 EGB07418.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EGB07418.1 - 0.15 11.8 0.6 0.28 11.0 0.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Orn_Arg_deC_N PF02784.16 EGB07419.1 - 1.6e-55 188.2 0.0 2e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGB07419.1 - 4.7e-10 39.6 0.0 1.3e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ephrin_rec_like PF07699.13 EGB07420.1 - 1e-39 134.0 84.7 2.2e-07 30.5 5.3 8.5 6 2 2 8 8 8 8 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB07420.1 - 1.2e-07 32.0 54.8 0.073 13.5 2.7 9.4 5 2 4 9 9 9 8 TNFR/NGFR cysteine-rich region eIF-1a PF01176.19 EGB07421.1 - 3.2e-20 71.7 0.1 3.7e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 EGB07421.1 - 0.00041 20.0 0.3 0.00061 19.5 0.1 1.5 1 1 1 2 2 2 1 RsgA N-terminal domain RNase_II_C_S1 PF18614.1 EGB07421.1 - 0.037 14.0 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain SAICAR_synt PF01259.18 EGB07422.1 - 8.5e-74 248.3 0.0 1.1e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Rav1p_C PF12234.8 EGB07423.1 - 2.1e-20 72.7 1.1 3e-20 72.2 1.1 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal DSPc PF00782.20 EGB07424.1 - 3.5e-06 26.8 0.0 4.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGB07424.1 - 0.00021 21.3 0.0 0.0003 20.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGB07424.1 - 0.00064 19.9 0.0 0.00082 19.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGB07424.1 - 0.0043 16.7 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase NTP_transferase PF00483.23 EGB07425.1 - 4.8e-11 42.7 0.0 2.7e-10 40.3 0.0 2.2 2 1 0 2 2 2 1 Nucleotidyl transferase GHMP_kinases_N PF00288.26 EGB07425.1 - 1.1e-10 41.5 0.0 3.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 EGB07425.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature HSF_DNA-bind PF00447.17 EGB07427.1 - 0.0013 19.3 0.0 0.0023 18.5 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding TFIIB PF00382.19 EGB07428.1 - 2e-30 104.7 1.5 5.2e-15 55.2 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGB07428.1 - 7e-25 87.3 0.4 7e-25 87.3 0.4 2.6 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EGB07428.1 - 2.4e-05 23.8 3.6 5.5e-05 22.6 3.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 EGB07428.1 - 0.024 14.3 3.1 0.037 13.7 2.0 1.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TylF PF05711.11 EGB07429.1 - 7.4e-30 104.1 0.1 1.9e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Macrocin-O-methyltransferase (TylF) GSIII_N PF12437.8 EGB07430.1 - 6.4e-49 165.7 0.0 2.3e-48 163.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EGB07430.1 - 9.8e-24 83.5 0.0 1.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EGB07430.1 - 1.7e-18 66.7 0.0 7.9e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain BACK PF07707.15 EGB07430.1 - 1.3e-14 54.1 0.1 7.5e-13 48.5 0.0 3.0 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 EGB07430.1 - 1.2e-13 51.3 0.0 2.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ank PF00023.30 EGB07431.1 - 4e-07 30.2 0.3 0.058 13.9 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGB07431.1 - 2.1e-06 28.2 0.0 4.7e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB07431.1 - 4.2e-06 27.2 0.3 5.5e-05 23.6 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB07431.1 - 8.5e-06 25.7 0.1 0.015 15.8 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB07431.1 - 2e-05 24.8 3.1 0.0069 16.7 0.5 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Peptidase_C1 PF00112.23 EGB07432.1 - 2.5e-76 256.6 6.1 3.3e-76 256.2 6.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB07432.1 - 3.9e-06 25.9 1.3 0.0038 16.1 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Cyclin_N PF00134.23 EGB07433.1 - 1.7e-19 69.8 0.1 2.5e-18 66.1 0.0 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGB07433.1 - 0.00016 21.7 0.0 0.00045 20.3 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain PHM7_cyt PF14703.6 EGB07434.1 - 0.0069 16.6 0.0 0.06 13.6 0.0 2.5 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter WD40 PF00400.32 EGB07435.1 - 8.8e-60 197.3 34.1 5.8e-10 39.6 0.6 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TORC_M PF12885.7 EGB07435.1 - 2e-05 24.6 0.0 1.9 8.4 0.0 4.0 1 1 4 5 5 5 2 Transducer of regulated CREB activity middle domain Frtz PF11768.8 EGB07435.1 - 3e-05 22.6 0.0 3.6 5.8 0.0 5.1 3 1 3 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 EGB07435.1 - 6.5e-05 23.2 3.3 0.8 10.0 0.1 4.3 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BppL_N PF18338.1 EGB07435.1 - 8.8e-05 22.1 1.8 1.1e+02 2.9 0.0 6.1 6 0 0 6 6 6 0 Lower baseplate protein N-terminal domain Ge1_WD40 PF16529.5 EGB07435.1 - 0.0014 17.6 8.4 1.1 8.2 1.2 4.4 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 EGB07435.1 - 0.0038 16.4 2.3 0.11 11.6 0.0 3.0 1 1 1 3 3 3 2 Protein of unknown function (DUF1513) WD40_3 PF15911.5 EGB07435.1 - 0.019 14.9 0.5 1.3e+02 2.6 0.0 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat HEPN_RnaseLS PF18869.1 EGB07435.1 - 0.036 14.2 0.7 10 6.2 0.1 2.7 2 1 1 3 3 3 0 RnaseLS-like HEPN IMP2_C PF18591.1 EGB07435.1 - 0.075 12.9 6.5 18 5.3 0.0 5.3 6 0 0 6 6 6 0 Immune Mapped Protein 2 (IMP2) C-terminal domain DUF5570 PF17731.1 EGB07435.1 - 0.95 9.6 12.9 5.7 7.1 0.2 3.9 1 1 4 5 5 5 0 Family of unknown function (DUF5570) eIF3m_C_helix PF18005.1 EGB07435.1 - 8.2 6.2 8.8 8.1 6.2 0.1 4.4 5 0 0 5 5 5 0 eIF3 subunit M, C-terminal helix Nup160 PF11715.8 EGB07435.1 - 9.6 4.7 17.0 1.6 7.3 0.1 4.1 1 1 4 5 5 5 0 Nucleoporin Nup120/160 O-FucT PF10250.9 EGB07436.1 - 2.2e-33 116.4 0.0 3.5e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SET PF00856.28 EGB07437.1 - 7e-20 72.1 0.0 2.5e-19 70.3 0.0 1.8 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EGB07437.1 - 2.4e-11 43.5 8.1 2.4e-11 43.5 8.1 2.5 3 0 0 3 3 3 1 AWS domain AMP-binding_C PF13193.6 EGB07438.1 - 2e-15 57.5 0.2 3.1e-15 56.9 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EGB07438.1 - 3.6e-14 52.2 0.1 6.5e-14 51.3 0.1 1.4 2 0 0 2 2 2 1 AMP-binding enzyme Ephrin_rec_like PF07699.13 EGB07439.1 - 5.8e-49 163.6 126.6 9.8e-08 31.6 1.2 12.0 7 3 5 12 12 12 10 Putative ephrin-receptor like zf-RRN7 PF11781.8 EGB07439.1 - 0.022 14.4 1.4 0.022 14.4 1.4 6.6 7 0 0 7 7 7 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TNFR_c6 PF00020.18 EGB07439.1 - 7.1 7.1 83.1 2.1 8.8 4.6 14.0 7 3 4 12 12 12 0 TNFR/NGFR cysteine-rich region Helicase_C PF00271.31 EGB07440.1 - 9e-12 45.3 0.0 1.3e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_60s PF00428.19 EGB07440.1 - 0.0052 17.3 2.8 0.0089 16.6 2.8 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein WD40 PF00400.32 EGB07441.1 - 6.2e-74 242.1 36.6 1.7e-07 31.8 0.0 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat Nup160 PF11715.8 EGB07441.1 - 6.7e-19 67.9 26.8 0.0062 15.2 0.1 10.8 4 2 6 10 10 10 10 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGB07441.1 - 1.6e-12 47.5 3.4 0.0097 16.2 0.1 6.7 1 1 7 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain DUF4597 PF15366.6 EGB07441.1 - 5.1e-09 35.7 3.0 1.5 8.6 0.1 7.3 4 3 4 8 8 8 3 Domain of unknown function (DUF4597) DUF1513 PF07433.11 EGB07441.1 - 3.5e-07 29.6 9.3 0.084 11.9 0.0 6.4 1 1 6 8 8 8 3 Protein of unknown function (DUF1513) WD40_like PF17005.5 EGB07441.1 - 0.036 13.4 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain LPD7 PF18821.1 EGB07441.1 - 0.055 13.6 0.0 1.3 9.2 0.0 3.2 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 7 Ret2_MD PF18528.1 EGB07441.1 - 0.074 13.4 0.0 7.6 7.0 0.0 3.5 3 1 1 4 4 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF2282 PF10048.9 EGB07441.1 - 9.1 6.4 10.8 9.3 6.3 0.8 4.6 4 0 0 4 4 4 0 Predicted integral membrane protein (DUF2282) CCDC24 PF15669.5 EGB07442.1 - 5.4e-39 134.2 1.4 5.4e-39 134.2 1.4 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family DUF935 PF06074.12 EGB07442.1 - 0.13 11.0 1.5 0.23 10.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF935) ADK PF00406.22 EGB07445.1 - 4.9e-53 179.3 0.0 6e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGB07445.1 - 1.4e-22 80.5 0.0 3.8e-22 79.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EGB07445.1 - 4.2e-13 49.0 0.0 9.5e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 EGB07445.1 - 9e-07 29.4 0.3 0.00073 19.9 0.2 2.3 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EGB07445.1 - 0.0003 21.0 0.0 0.00074 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EGB07445.1 - 0.0078 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_22 PF13401.6 EGB07445.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGB07445.1 - 0.14 12.7 0.0 0.24 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGB07445.1 - 0.15 12.5 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EF-hand_8 PF13833.6 EGB07446.1 - 8.1e-22 76.8 4.5 3.7e-12 45.9 0.8 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 EGB07446.1 - 1.1e-20 73.8 1.3 1.2e-13 51.3 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB07446.1 - 2.7e-20 70.3 8.6 5.5e-08 31.8 1.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGB07446.1 - 7.3e-16 56.7 2.3 3.1e-06 26.7 0.1 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EGB07446.1 - 5.7e-10 38.2 4.7 0.00059 19.2 0.1 3.8 3 1 1 4 4 4 2 EF hand EF-hand_9 PF14658.6 EGB07446.1 - 4.8e-08 33.2 0.2 0.0065 16.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGB07446.1 - 0.0023 17.8 1.0 0.022 14.7 0.4 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 EGB07446.1 - 0.003 17.7 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 p25-alpha EF-hand_11 PF08976.11 EGB07446.1 - 0.016 16.1 0.0 9.2 7.2 0.0 2.1 1 1 0 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 EGB07446.1 - 0.066 13.0 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain TerB PF05099.13 EGB07446.1 - 0.12 12.4 0.4 0.63 10.0 0.1 2.3 1 1 3 4 4 4 0 Tellurite resistance protein TerB Glycos_trans_3N PF02885.17 EGB07446.1 - 0.19 11.6 4.6 44 4.0 0.0 4.0 3 1 1 4 4 4 0 Glycosyl transferase family, helical bundle domain Kinesin PF00225.23 EGB07447.1 - 3.9e-79 266.0 0.0 4.7e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB07447.1 - 9e-14 51.7 0.0 1.6e-12 47.6 0.0 2.2 1 1 0 1 1 1 1 Microtubule binding Ras PF00071.22 EGB07448.1 - 3.2e-52 176.4 4.1 7.5e-50 168.7 4.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGB07448.1 - 1.6e-27 96.1 0.5 3.7e-27 94.9 0.5 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB07448.1 - 4e-15 55.7 1.6 2.2e-14 53.3 0.8 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB07448.1 - 4.9e-05 22.8 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB07448.1 - 0.00011 22.2 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB07448.1 - 0.00072 19.0 0.5 0.0017 17.9 0.1 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGB07448.1 - 0.00076 19.1 0.4 0.021 14.4 0.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB07448.1 - 0.018 14.9 0.0 6.9 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EGB07448.1 - 0.054 13.0 0.0 7.8 6.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 EGB07448.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein START PF01852.19 EGB07450.1 - 0.0084 15.5 0.0 0.042 13.2 0.0 2.0 1 1 0 1 1 1 1 START domain 2-Hacid_dh PF00389.30 EGB07450.1 - 0.1 12.2 0.0 0.38 10.4 0.0 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain TAXi_N PF14543.6 EGB07451.1 - 4.9e-26 92.0 5.0 5.7e-26 91.8 5.0 1.1 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 EGB07451.1 - 2.4e-11 43.6 2.1 6.5e-10 38.9 2.1 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EGB07451.1 - 0.072 13.7 0.0 0.36 11.5 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease AhpC-TSA_2 PF13911.6 EGB07452.1 - 4e-15 55.9 0.0 6.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGB07452.1 - 7.2e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family TPR_1 PF00515.28 EGB07453.1 - 2e-11 43.2 7.7 0.0001 22.0 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07453.1 - 4.2e-11 42.1 14.9 0.00017 21.4 0.1 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB07453.1 - 9.2e-10 38.5 16.0 0.0016 19.1 0.1 5.7 2 2 5 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07453.1 - 1.3e-08 35.2 15.6 0.0086 16.6 0.5 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07453.1 - 4e-06 26.6 13.4 0.096 12.9 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB07453.1 - 5.4e-05 23.3 11.2 0.19 11.9 0.0 3.6 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGB07453.1 - 6.7e-05 22.6 10.1 1.7 8.8 0.3 5.2 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB07453.1 - 9.3e-05 22.6 18.0 0.47 10.8 0.3 5.4 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB07453.1 - 0.00026 21.1 3.8 0.22 11.7 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB07453.1 - 0.00028 21.5 16.8 0.39 11.4 0.5 4.6 3 1 0 4 4 4 3 Tetratricopeptide repeat ELYS PF13934.6 EGB07453.1 - 0.0016 18.5 4.2 0.0034 17.4 1.1 2.1 1 1 1 2 2 2 1 Nuclear pore complex assembly TPR_15 PF13429.6 EGB07453.1 - 0.0047 16.2 10.5 0.072 12.3 2.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGB07453.1 - 0.02 14.3 1.4 0.031 13.7 0.1 2.0 2 0 0 2 2 2 0 SHNi-TPR TPR_11 PF13414.6 EGB07453.1 - 0.023 14.4 16.4 0.032 13.9 1.6 4.9 5 1 1 6 6 6 0 TPR repeat TPR_17 PF13431.6 EGB07453.1 - 0.031 14.7 1.7 2.8 8.5 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Pilin_GH PF16734.5 EGB07453.1 - 0.046 14.0 1.1 0.36 11.2 0.1 2.2 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative TPR_6 PF13174.6 EGB07453.1 - 1.7 9.4 9.2 3.2 8.6 0.1 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 EGB07454.1 - 6e-55 186.4 0.0 6.8e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07454.1 - 2.9e-24 85.8 0.0 5.7e-24 84.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB07454.1 - 0.002 17.5 0.0 0.0056 16.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB07454.1 - 0.02 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Brix PF04427.18 EGB07455.1 - 1e-38 133.4 0.0 1.2e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 Brix domain Glyco_transf_41 PF13844.6 EGB07456.1 - 3.3e-35 121.4 0.0 5.4e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_17 PF13431.6 EGB07456.1 - 1.7e-14 53.1 7.9 0.0013 19.0 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB07456.1 - 6.5e-13 48.1 16.4 1.1e-05 25.0 0.6 6.1 7 0 0 7 7 7 3 TPR repeat TPR_7 PF13176.6 EGB07456.1 - 1.6e-12 46.5 10.4 0.028 14.4 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07456.1 - 1.9e-09 36.9 41.0 0.0012 18.8 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB07456.1 - 2.1e-08 34.7 32.9 3.3e-06 27.6 4.2 11.3 7 2 4 11 11 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07456.1 - 3e-08 33.2 19.8 2.5 8.5 0.0 8.8 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB07456.1 - 3.3e-08 33.0 21.9 1.1 9.2 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07456.1 - 5.3e-08 33.3 26.5 0.00071 20.0 0.0 6.3 4 2 1 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGB07456.1 - 2.3e-05 24.6 38.6 0.0068 16.7 0.9 7.9 4 3 2 7 7 7 3 Tetratricopeptide repeat Glyco_transf_4 PF13439.6 EGB07456.1 - 0.015 15.3 1.9 0.057 13.4 0.1 2.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 TOM20_plant PF06552.12 EGB07456.1 - 0.027 14.2 0.1 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_4 PF07721.14 EGB07456.1 - 0.084 13.5 0.2 0.45 11.3 0.0 10.1 10 0 0 10 10 6 0 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 EGB07456.1 - 0.099 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 TPR_10 PF13374.6 EGB07456.1 - 3.9 7.5 43.8 0.35 10.8 0.2 8.2 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB07456.1 - 7.5 7.4 23.7 26 5.7 0.0 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat CH PF00307.31 EGB07457.1 - 2.8e-16 59.6 0.0 3.5e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EGB07457.1 - 0.059 13.6 0.0 0.084 13.1 0.0 1.2 1 0 0 1 1 1 0 CDC24 Calponin Ceramidase PF05875.12 EGB07460.1 - 6.6e-19 68.4 0.0 1.2e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Ceramidase zf-PARP PF00645.18 EGB07460.1 - 3.1e-10 40.8 0.3 5.3e-10 40.0 0.3 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region 14-3-3 PF00244.20 EGB07462.1 - 6e-102 339.8 2.9 6.8e-102 339.7 2.9 1.0 1 0 0 1 1 1 1 14-3-3 protein GPI PF06560.11 EGB07462.1 - 0.0034 16.7 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) TPR_19 PF14559.6 EGB07462.1 - 0.056 14.0 1.0 0.5 10.9 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EGB07463.1 - 1.6e-35 122.8 0.0 1.4e-33 116.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L27A PF00828.19 EGB07464.1 - 2.5e-28 99.3 0.0 3.7e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 EGB07464.1 - 5.5e-05 22.6 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e DUF2585 PF10755.9 EGB07465.1 - 9.2e-10 38.5 1.4 1.4e-09 37.9 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2585) Methyltransf_24 PF13578.6 EGB07466.1 - 2e-10 41.6 0.1 7e-10 39.9 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB07466.1 - 0.00065 19.6 0.0 0.0072 16.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain GST_N_2 PF13409.6 EGB07467.1 - 2.4e-13 50.2 0.0 5.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB07467.1 - 1.1e-11 44.6 0.7 2.2e-11 43.6 0.7 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB07467.1 - 7.6e-08 32.5 0.0 6e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGB07467.1 - 5.7e-06 26.0 0.1 1.1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGB07467.1 - 0.00053 20.1 0.0 0.0009 19.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB07467.1 - 0.017 15.6 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.27 EGB07468.1 - 3.9e-34 116.4 11.6 1e-13 51.0 0.7 4.2 2 2 2 4 4 4 4 Mitochondrial carrier protein MRP-S33 PF08293.11 EGB07470.1 - 4.5e-19 68.5 0.0 5.7e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF1126 PF06565.12 EGB07471.1 - 3e-71 235.9 0.0 3.9e-23 81.3 0.0 3.5 3 0 0 3 3 3 3 DUF1126 PH-like domain UCH PF00443.29 EGB07471.1 - 5.9e-27 94.8 0.0 1.4e-26 93.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGB07471.1 - 9.7e-15 54.7 4.4 2.9e-14 53.1 4.4 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein EF-hand_6 PF13405.6 EGB07471.1 - 0.052 13.5 0.0 27 5.0 0.0 3.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EGB07471.1 - 0.12 12.0 0.0 14 5.5 0.0 2.8 2 0 0 2 2 2 0 EF hand zf-UBP_var PF17807.1 EGB07471.1 - 3.8 7.3 9.2 0.27 11.0 2.6 2.5 4 0 0 4 4 4 0 Variant UBP zinc finger Pkinase PF00069.25 EGB07472.1 - 1.5e-58 198.3 0.0 1.9e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07472.1 - 5.7e-24 84.8 0.0 7.2e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB07472.1 - 3.8e-05 23.2 0.0 4.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB07472.1 - 0.016 14.0 0.0 0.35 9.6 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGB07472.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Str_synth PF03088.16 EGB07473.1 - 9.2e-16 57.7 0.0 5.3e-15 55.3 0.0 2.2 1 1 1 2 2 2 1 Strictosidine synthase SGL PF08450.12 EGB07473.1 - 1.6e-15 57.4 0.0 2.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_2 PF13360.6 EGB07473.1 - 0.00019 21.1 0.2 0.0047 16.5 0.2 2.2 1 1 0 1 1 1 1 PQQ-like domain NHL PF01436.21 EGB07473.1 - 0.14 12.3 0.3 80 3.6 0.1 4.0 4 0 0 4 4 4 0 NHL repeat GDP_Man_Dehyd PF16363.5 EGB07474.1 - 2e-60 205.0 0.0 6.5e-60 203.3 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGB07474.1 - 7.6e-53 179.4 0.0 8.9e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB07474.1 - 4.2e-20 71.9 0.0 5.3e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGB07474.1 - 1.2e-13 50.9 0.0 1.3e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGB07474.1 - 9.9e-10 38.0 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGB07474.1 - 1.9e-08 33.8 0.0 1.4e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EGB07474.1 - 0.0011 18.4 0.3 0.01 15.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EGB07474.1 - 0.0042 17.0 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGB07474.1 - 0.0058 16.5 0.0 0.017 15.0 0.0 1.7 1 1 0 1 1 1 1 KR domain Na_H_Exchanger PF00999.21 EGB07475.1 - 1.4e-58 198.5 47.9 1.9e-58 198.1 47.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EGB07475.1 - 1.6e-20 73.5 1.6 3.4e-20 72.4 1.6 1.6 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EGB07475.1 - 0.0012 19.1 0.2 0.0024 18.2 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EGB07475.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EGB07475.1 - 0.032 13.7 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GerA PF03323.13 EGB07475.1 - 1.8 6.9 4.7 3 6.2 4.7 1.3 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein ketoacyl-synt PF00109.26 EGB07476.1 - 3.1e-41 141.6 4.0 4e-41 141.3 4.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB07476.1 - 8.9e-06 25.7 0.1 0.00011 22.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain DUF936 PF06075.12 EGB07476.1 - 0.33 9.8 1.1 0.45 9.4 1.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Dioxygenase_C PF00775.21 EGB07477.1 - 1.4e-07 31.1 0.0 0.0074 15.7 0.0 2.7 2 1 0 2 2 2 2 Dioxygenase TraB PF01963.17 EGB07478.1 - 2.5e-17 63.7 0.0 5.5e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 TraB family Cofac_haem_bdg PF04187.13 EGB07478.1 - 0.059 13.3 0.1 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN 2OG-FeII_Oxy_3 PF13640.6 EGB07479.1 - 1.1e-05 26.2 0.0 2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EGB07479.1 - 0.18 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase HATPase_c_3 PF13589.6 EGB07480.1 - 1e-13 51.3 0.1 9.3e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SET PF00856.28 EGB07480.1 - 0.00062 20.2 0.0 0.0024 18.3 0.0 2.1 1 0 0 1 1 1 1 SET domain SfsA PF03749.13 EGB07481.1 - 4.3e-24 85.0 0.0 7.1e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 EGB07481.1 - 7.9e-18 64.4 0.0 1.6e-16 60.2 0.1 2.4 2 0 0 2 2 2 1 SfsA N-terminal OB domain CN_hydrolase PF00795.22 EGB07482.1 - 2.8e-45 154.7 0.0 3.2e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Chloroa_b-bind PF00504.21 EGB07483.1 - 3.7e-29 102.3 0.0 5.2e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Methyltransf_11 PF08241.12 EGB07484.1 - 7.1e-14 52.2 0.1 1.4e-13 51.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB07484.1 - 2.4e-11 44.2 0.1 5.4e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB07484.1 - 3.8e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB07484.1 - 4.6e-06 26.1 0.0 1.1e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGB07484.1 - 0.012 15.4 0.0 0.049 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB07484.1 - 0.017 15.8 0.0 0.065 14.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 EGB07484.1 - 0.069 12.2 0.0 0.098 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_S27e PF01667.17 EGB07485.1 - 1.2e-28 98.6 5.6 1.5e-28 98.3 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EGB07485.1 - 0.041 13.4 1.0 0.067 12.7 1.0 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Mu-like_Com PF10122.9 EGB07485.1 - 0.082 12.4 1.5 7.5 6.1 0.0 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com Aminotran_1_2 PF00155.21 EGB07486.1 - 7e-29 101.1 0.0 7.7e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_transf_49 PF13896.6 EGB07487.1 - 5.6e-26 91.7 0.0 2.3e-09 37.1 0.0 3.7 2 2 1 3 3 3 3 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 EGB07487.1 - 0.03 14.1 0.0 0.076 12.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Thioredoxin PF00085.20 EGB07488.1 - 3.4e-20 72.0 0.0 3.6e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB07488.1 - 0.00025 21.5 0.2 0.038 14.5 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EGB07488.1 - 0.0021 17.8 0.1 0.0042 16.8 0.1 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGB07488.1 - 0.005 17.1 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EGB07488.1 - 0.0067 16.6 0.2 0.021 15.0 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EGB07488.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 EGB07488.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 EGB07488.1 - 0.051 12.9 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 EGB07488.1 - 0.094 12.5 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein EF-hand_7 PF13499.6 EGB07489.1 - 5e-21 74.9 10.0 3.4e-07 30.6 0.6 5.5 4 1 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EGB07489.1 - 1.9e-16 58.3 10.8 0.13 11.8 1.0 8.3 9 0 0 9 9 9 6 EF hand EF-hand_6 PF13405.6 EGB07489.1 - 4.9e-16 57.2 6.7 0.27 11.3 0.0 7.8 8 0 0 8 8 8 5 EF-hand domain EF-hand_8 PF13833.6 EGB07489.1 - 5e-13 48.7 7.0 0.00066 19.5 0.3 6.2 5 1 1 6 6 6 4 EF-hand domain pair Telomere_Sde2_2 PF13297.6 EGB07489.1 - 0.0011 18.6 0.1 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SPARC_Ca_bdg PF10591.9 EGB07489.1 - 0.011 16.0 3.4 44 4.4 0.0 4.8 5 1 1 6 6 6 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 EGB07489.1 - 0.39 10.3 17.7 3.8 7.2 0.0 6.8 8 0 0 8 8 8 0 EF hand EF-hand_4 PF12763.7 EGB07489.1 - 4.5 7.3 9.4 1.2 9.2 0.2 3.9 4 2 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand SET PF00856.28 EGB07490.1 - 1.8e-09 38.2 0.0 3.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EGB07490.1 - 0.001 19.8 0.1 0.002 18.9 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Mito_carr PF00153.27 EGB07491.1 - 2.1e-47 159.0 5.2 8.8e-17 60.8 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M16 PF00675.20 EGB07491.1 - 1.5e-32 112.6 0.0 2.7e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 EGB07491.1 - 2.4e-26 92.7 0.0 3.7e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EGB07491.1 - 2.1e-11 44.2 0.0 4.1e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain ZZ PF00569.17 EGB07491.1 - 1.6e-09 37.4 1.5 2.8e-09 36.6 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 EGB07491.1 - 1.6e-05 24.7 0.2 7.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 PB1 domain tRNA-synt_1g PF09334.11 EGB07492.1 - 1.2e-84 284.4 0.0 2.3e-45 155.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGB07492.1 - 4e-26 91.4 0.0 2.2e-13 49.3 0.0 3.0 2 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 EGB07492.1 - 3.2e-21 75.2 0.0 5.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 EGB07492.1 - 2.2e-10 40.4 0.0 2.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGB07492.1 - 0.0001 21.3 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 EGB07492.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA DnaJ PF00226.31 EGB07494.1 - 1e-05 25.6 0.0 1.6e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EGB07494.1 - 4.4e-05 23.5 0.0 4.7e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Pam16 GAF PF01590.26 EGB07496.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 GAF domain Translin PF01997.16 EGB07497.1 - 1.6e-09 38.0 0.0 1.8e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Translin family Aa_trans PF01490.18 EGB07498.1 - 2.2e-17 62.9 14.7 1.7e-16 60.0 14.7 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Flavodoxin_1 PF00258.25 EGB07499.1 - 3.7e-17 62.9 0.1 4.9e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EGB07499.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin domain AhpC-TSA PF00578.21 EGB07499.1 - 0.006 16.5 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Flavodoxin_3 PF12641.7 EGB07499.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.8 1 1 0 1 1 1 0 Flavodoxin domain Cation_ATPase_N PF00690.26 EGB07501.1 - 0.0092 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Glyco_hydro_16 PF00722.21 EGB07502.1 - 1.6e-33 115.6 0.7 2.9e-33 114.8 0.2 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGB07502.1 - 7.8e-16 57.5 0.3 5.7e-08 31.6 0.0 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) PT PF04886.12 EGB07503.1 - 5e-05 22.7 16.8 5e-05 22.7 16.8 8.4 3 3 3 6 6 6 3 PT repeat Na_H_antiport_1 PF06965.12 EGB07504.1 - 1.5e-95 320.2 21.9 1.7e-95 320.1 21.9 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 MatE PF01554.18 EGB07505.1 - 2.9e-18 66.1 37.2 1.4e-11 44.3 8.1 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGB07505.1 - 2.5e-07 30.8 7.2 2.5e-07 30.8 7.2 3.4 2 2 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Neur_chan_LBD PF02931.23 EGB07506.1 - 1.9e-06 27.5 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain AAA_11 PF13086.6 EGB07507.1 - 7.7e-52 176.7 2.0 1.7e-51 175.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EGB07507.1 - 2e-45 154.9 0.0 2.9e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB07507.1 - 2e-11 44.0 7.0 4.4e-09 36.3 0.5 3.9 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EGB07507.1 - 1.3e-09 38.5 0.8 8.9e-08 32.6 0.0 3.0 3 1 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 EGB07507.1 - 1.2e-05 25.2 0.3 0.33 10.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase R3H PF01424.22 EGB07507.1 - 3.7e-05 23.6 0.0 8.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain AAA PF00004.29 EGB07507.1 - 4.9e-05 23.8 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB07507.1 - 0.00013 22.4 0.7 0.00013 22.4 0.7 3.4 3 0 0 3 3 3 1 AAA ATPase domain PIF1 PF05970.14 EGB07507.1 - 0.00025 20.4 0.0 0.0059 15.8 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase AAA_22 PF13401.6 EGB07507.1 - 0.00037 20.8 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB07507.1 - 0.00048 19.9 0.4 0.0012 18.6 0.4 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_33 PF13671.6 EGB07507.1 - 0.00055 20.1 0.4 0.0025 18.0 0.4 2.2 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EGB07507.1 - 0.0014 18.2 0.1 0.0025 17.4 0.1 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EGB07507.1 - 0.0027 17.6 4.0 0.012 15.5 0.3 3.0 2 1 0 3 3 3 1 Helicase ubiquitin PF00240.23 EGB07507.1 - 0.0045 16.7 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Zot PF05707.12 EGB07507.1 - 0.0045 16.6 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) ResIII PF04851.15 EGB07507.1 - 0.016 15.2 0.0 0.071 13.1 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EGB07507.1 - 0.021 14.1 0.0 0.099 11.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EGB07507.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EGB07507.1 - 0.21 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 KaiC Pkinase PF00069.25 EGB07508.1 - 2.2e-59 201.0 0.0 2.5e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07508.1 - 1.7e-32 112.8 0.0 1.9e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB07508.1 - 5.8e-08 32.4 0.0 9.2e-08 31.7 0.0 1.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGB07508.1 - 4.1e-05 23.6 0.6 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB07508.1 - 0.0012 18.2 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB07508.1 - 0.0034 16.2 0.0 0.0048 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGB07508.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 EGB07509.1 - 1.1e-29 103.0 0.0 1.9e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family MFS_1 PF07690.16 EGB07510.1 - 1.3e-15 57.2 47.9 1.1e-11 44.3 18.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB07510.1 - 1.1e-05 24.5 4.4 1.1e-05 24.5 4.4 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGB07510.1 - 5.1 5.8 7.6 0.52 9.1 2.6 1.7 2 0 0 2 2 2 0 MFS_1 like family cNMP_binding PF00027.29 EGB07511.1 - 1.2e-13 50.9 0.0 3.7e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB07511.1 - 8.5e-07 28.4 0.9 1.4e-06 27.7 0.9 1.2 1 0 0 1 1 1 1 Ion transport protein Arf PF00025.21 EGB07512.1 - 4.4e-58 195.6 0.0 5e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGB07512.1 - 1.3e-08 34.5 0.3 4.3e-05 22.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGB07512.1 - 1.5e-07 31.7 0.0 3.4e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGB07512.1 - 5.7e-07 29.6 0.0 7.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EGB07512.1 - 1.5e-06 27.9 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGB07512.1 - 2.4e-06 27.1 0.0 3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGB07512.1 - 7.3e-05 22.2 0.0 8.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGB07512.1 - 0.031 13.8 0.0 2.6 7.5 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EGB07512.1 - 0.038 14.5 0.0 0.069 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGB07512.1 - 0.039 13.5 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EGB07512.1 - 0.079 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RRM_1 PF00076.22 EGB07513.1 - 3.7e-37 126.0 0.0 1.6e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB07513.1 - 3.3e-06 27.1 0.0 3.3e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 EGB07513.1 - 3.5e-06 26.6 0.3 0.035 13.8 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 EGB07513.1 - 0.0003 20.4 0.0 0.045 13.3 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGB07513.1 - 0.08 13.2 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Isochorismatase PF00857.20 EGB07514.1 - 3.8e-08 33.7 0.8 1.4e-06 28.7 0.8 2.6 1 1 0 1 1 1 1 Isochorismatase family Lactamase_B_6 PF16661.5 EGB07515.1 - 1.7e-43 148.3 0.0 1.9e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EGB07515.1 - 3.1e-05 23.6 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGB07515.1 - 0.00059 19.9 0.9 0.00084 19.4 0.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TMEM117 PF15113.6 EGB07516.1 - 4.4e-24 85.2 3.4 1.1e-23 83.8 3.4 1.6 1 1 0 1 1 1 1 TMEM117 protein family BT1 PF03092.16 EGB07517.1 - 6.6e-86 288.6 5.5 4.4e-46 157.2 0.1 2.1 2 0 0 2 2 2 2 BT1 family MFS_2 PF13347.6 EGB07517.1 - 1.7e-07 30.2 3.3 1.7e-07 30.2 3.3 1.8 2 1 0 2 2 2 1 MFS/sugar transport protein FAD_binding_3 PF01494.19 EGB07518.1 - 1.4e-18 67.3 0.0 3.2e-18 66.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB07518.1 - 0.00045 19.6 0.2 0.004 16.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB07518.1 - 0.00069 18.8 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGB07518.1 - 0.0043 16.1 0.1 1.7 7.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGB07518.1 - 0.0063 16.7 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB07518.1 - 0.0065 16.1 3.3 0.52 9.8 3.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB07518.1 - 0.012 16.1 0.3 0.049 14.2 0.3 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGB07518.1 - 0.1 11.7 0.0 0.66 9.0 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 EGB07518.1 - 0.13 11.1 0.1 0.82 8.4 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase VDE PF07137.11 EGB07519.1 - 8.3e-91 303.7 4.8 9.3e-91 303.6 4.8 1.0 1 0 0 1 1 1 1 VDE lipocalin domain Kelch_4 PF13418.6 EGB07521.1 - 2.1e-11 43.6 10.4 0.083 12.9 0.2 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB07521.1 - 5.4e-11 42.2 10.9 0.017 15.1 0.2 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EGB07521.1 - 0.00043 20.2 7.1 2.3 8.4 0.5 5.1 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EGB07521.1 - 0.0022 18.2 7.5 6.4 7.2 0.4 5.5 5 2 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EGB07521.1 - 0.63 9.7 15.5 0.23 11.1 0.2 5.1 5 1 0 5 5 5 0 Kelch motif Kelch_3 PF13415.6 EGB07525.1 - 6.4e-22 77.3 15.6 2.6e-08 33.9 0.5 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB07525.1 - 1.7e-21 75.7 16.1 8e-07 28.9 0.1 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 EGB07525.1 - 1.9e-18 66.2 19.5 2.9e-08 33.6 0.3 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGB07525.1 - 8.3e-15 54.5 14.8 0.00045 20.4 0.1 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGB07525.1 - 1.1e-10 40.9 19.1 3.4e-05 23.3 0.6 5.5 5 0 0 5 5 5 4 Kelch motif Aminotran_5 PF00266.19 EGB07525.1 - 1.9e-07 30.4 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Kelch_2 PF07646.15 EGB07525.1 - 0.0004 20.2 14.8 0.89 9.6 0.5 5.3 5 0 0 5 5 5 3 Kelch motif Porphobil_deam PF01379.20 EGB07526.1 - 3.8e-75 251.9 0.0 4.9e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGB07526.1 - 3.3e-17 62.6 0.1 6.4e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain BAGE PF08180.11 EGB07526.1 - 0.3 11.2 5.1 0.77 9.9 5.1 1.7 1 0 0 1 1 1 0 B melanoma antigen family H2TH PF06831.14 EGB07527.1 - 1.9e-21 75.9 0.0 3.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 EGB07527.1 - 1.6e-06 28.7 0.1 2.7e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Zn_Tnp_IS1595 PF12760.7 EGB07527.1 - 8.4e-05 22.5 2.9 0.00016 21.6 2.9 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain C1_1 PF00130.22 EGB07527.1 - 0.0099 15.8 0.5 0.017 15.0 0.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.12 EGB07527.1 - 0.059 12.9 0.2 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-FPG_IleRS PF06827.14 EGB07527.1 - 0.13 12.1 1.5 0.3 11.0 1.5 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-HYPF PF07503.12 EGB07527.1 - 0.21 11.4 0.2 0.21 11.4 0.2 1.8 2 0 0 2 2 2 0 HypF finger Utp11 PF03998.13 EGB07528.1 - 1.1e-50 172.9 19.3 1.3e-50 172.7 19.3 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EGB07528.1 - 0.0024 17.2 0.6 0.0043 16.4 0.6 1.4 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 Sulfotransfer_2 PF03567.14 EGB07532.1 - 3.3e-05 23.9 0.0 5.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Serum_albumin PF00273.20 EGB07532.1 - 0.19 11.5 3.6 0.31 10.8 3.6 1.2 1 0 0 1 1 1 0 Serum albumin family Tex_N PF09371.10 EGB07532.1 - 5.1 6.7 7.0 40 3.8 1.5 2.9 2 1 0 3 3 3 0 Tex-like protein N-terminal domain Phos_pyr_kin PF08543.12 EGB07533.1 - 1.2e-67 227.9 0.2 1.4e-67 227.6 0.2 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGB07533.1 - 0.028 13.7 5.9 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Carb_kinase PF01256.17 EGB07533.1 - 0.079 12.4 6.6 0.14 11.6 6.6 1.6 1 1 0 1 1 1 0 Carbohydrate kinase HK PF02110.15 EGB07533.1 - 0.086 12.2 5.4 0.19 11.1 5.4 1.7 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family AAA_2 PF07724.14 EGB07535.1 - 6.4e-21 75.2 0.0 1.2e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) FAM183 PF14886.6 EGB07535.1 - 5e-18 65.8 0.0 9.9e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 FAM183A and FAM183B related AAA PF00004.29 EGB07535.1 - 1.8e-12 47.8 0.0 3.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGB07535.1 - 2.1e-05 24.5 0.1 5.5e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 EGB07535.1 - 5.8e-05 22.3 0.0 9.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 EGB07535.1 - 7.4e-05 23.2 0.2 0.00035 21.0 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 EGB07535.1 - 0.00019 21.5 0.0 0.003 17.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) LLC1 PF14945.6 EGB07535.1 - 0.00099 19.7 0.3 0.0021 18.6 0.3 1.5 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Mg_chelatase PF01078.21 EGB07535.1 - 0.0025 17.2 0.4 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 EGB07535.1 - 0.003 17.3 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation LRR_8 PF13855.6 EGB07535.1 - 0.0033 17.2 1.1 0.083 12.7 0.2 2.0 1 1 1 2 2 2 2 Leucine rich repeat IstB_IS21 PF01695.17 EGB07535.1 - 0.0046 16.7 0.1 0.013 15.2 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein Rad17 PF03215.15 EGB07535.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 EGB07535.1 - 0.0079 16.4 0.0 0.36 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGB07535.1 - 0.011 16.2 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EGB07535.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGB07535.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB07535.1 - 0.034 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGB07535.1 - 0.058 13.9 0.0 0.058 13.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain SRPRB PF09439.10 EGB07535.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 EGB07535.1 - 0.091 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EGB07535.1 - 0.091 12.9 1.9 0.17 12.0 0.0 2.5 2 0 0 2 2 1 0 AAA domain Cytidylate_kin PF02224.18 EGB07535.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase TsaE PF02367.17 EGB07535.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_7 PF13499.6 EGB07536.1 - 4.3e-25 88.0 0.9 5.9e-12 45.9 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB07536.1 - 2.8e-22 76.6 1.1 0.00015 21.1 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB07536.1 - 2.8e-18 64.2 0.8 0.011 15.6 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB07536.1 - 5e-15 55.1 5.6 6.7e-07 29.1 0.0 4.4 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB07536.1 - 4.3e-14 51.3 0.4 0.016 14.7 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 EGB07536.1 - 1.9e-05 24.6 0.1 0.045 13.7 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 EGB07536.1 - 0.0038 18.1 0.0 0.14 13.0 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB07536.1 - 0.013 15.8 0.2 9.6 6.6 0.0 2.9 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 EGB07537.1 - 2.5e-14 53.8 6.9 2.5e-14 53.8 6.9 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGB07537.1 - 1.3e-13 50.9 0.0 1e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGB07537.1 - 0.0067 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) CS PF04969.16 EGB07537.1 - 0.036 15.1 0.0 0.096 13.7 0.1 1.7 2 0 0 2 2 2 0 CS domain Choline_kinase PF01633.20 EGB07537.1 - 0.038 13.6 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PGA2 PF07543.12 EGB07537.1 - 0.43 10.6 3.7 0.97 9.4 3.7 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 cNMP_binding PF00027.29 EGB07538.1 - 6.2e-20 71.1 0.1 7.5e-20 70.8 0.1 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TUG-UBL1 PF11470.8 EGB07539.1 - 1.3e-13 51.0 0.0 2.6e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EGB07539.1 - 3e-08 33.8 0.0 5.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain PUB PF09409.10 EGB07539.1 - 8.6e-08 32.0 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PUB domain ABC_tran PF00005.27 EGB07540.1 - 5.6e-51 172.7 0.0 3.5e-30 105.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGB07540.1 - 2.7e-40 138.7 19.4 4.8e-31 108.4 1.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGB07540.1 - 2.4e-07 30.4 0.9 0.023 14.2 0.0 3.7 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB07540.1 - 6.3e-07 29.9 0.4 0.00087 19.7 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 EGB07540.1 - 5e-06 26.2 2.0 0.064 12.8 0.4 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGB07540.1 - 1.7e-05 24.9 0.1 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGB07540.1 - 7.7e-05 22.6 1.3 0.2 11.4 0.0 3.6 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGB07540.1 - 0.00026 21.3 0.5 0.51 10.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EGB07540.1 - 0.00069 18.8 0.8 0.081 12.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EGB07540.1 - 0.00078 19.4 0.1 0.91 9.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGB07540.1 - 0.001 18.8 4.1 0.55 10.0 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGB07540.1 - 0.0024 17.3 0.4 0.12 11.7 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 EGB07540.1 - 0.0032 17.6 1.0 0.093 12.8 0.1 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 EGB07540.1 - 0.0038 17.3 4.7 0.66 10.0 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 EGB07540.1 - 0.0073 16.8 3.2 0.42 11.1 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EGB07540.1 - 0.03 14.0 3.0 4.3 7.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGB07540.1 - 0.035 13.3 0.1 0.97 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CbiA PF01656.23 EGB07540.1 - 0.047 13.7 0.0 16 5.6 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TrwB_AAD_bind PF10412.9 EGB07540.1 - 0.068 12.1 0.4 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 EGB07540.1 - 0.081 12.2 1.3 4.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EGB07540.1 - 0.087 13.2 0.2 7.2 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 EGB07540.1 - 0.11 11.8 1.4 0.36 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EGB07540.1 - 0.12 12.6 0.1 18 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB07540.1 - 0.22 12.0 1.6 30 5.2 0.1 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 EGB07540.1 - 0.27 11.2 1.8 2.4 8.0 0.0 2.8 3 0 0 3 3 2 0 NACHT domain ABC_membrane_2 PF06472.15 EGB07540.1 - 1 8.7 8.6 0.15 11.4 3.0 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 Aconitase PF00330.20 EGB07541.1 - 7.5e-159 529.6 0.1 9e-159 529.3 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGB07541.1 - 4.1e-35 121.0 0.0 6.6e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EGB07541.1 - 0.0051 15.6 0.0 0.0079 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Aminotran_5 PF00266.19 EGB07542.1 - 2.2e-41 142.0 0.0 2.5e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGB07542.1 - 1.4e-06 27.2 0.0 1.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGB07542.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase VEFS-Box PF09733.9 EGB07543.1 - 1.1e-31 109.5 0.2 1.3e-31 109.2 0.2 1.0 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Cupin_8 PF13621.6 EGB07545.1 - 2.7e-20 73.2 0.0 4.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain RGS PF00615.19 EGB07545.1 - 9.1e-08 32.4 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Cupin_4 PF08007.12 EGB07545.1 - 8.5e-07 28.7 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein SNF2_N PF00176.23 EGB07546.1 - 3.3e-26 91.8 0.0 7.9e-26 90.6 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB07546.1 - 0.0023 18.3 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2_jaz PF12171.8 EGB07546.1 - 0.074 13.4 0.3 7.3 7.0 2.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGB07546.1 - 0.33 11.5 2.9 1.1 9.8 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGB07546.1 - 0.75 10.8 4.4 1.3 10.0 0.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Aminotran_3 PF00202.21 EGB07547.1 - 1.8e-74 250.8 0.0 3.8e-73 246.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGB07547.1 - 0.00068 18.9 0.0 0.0012 18.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3999 PF13163.6 EGB07548.1 - 0.17 11.1 4.9 0.39 9.9 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3999) RCC_reductase PF06405.11 EGB07549.1 - 0.0033 16.7 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) Chlorophyllase2 PF12740.7 EGB07549.1 - 0.022 13.7 0.0 0.063 12.2 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EGB07549.1 - 0.052 13.2 0.3 0.57 9.8 0.1 2.4 1 1 2 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGB07549.1 - 0.12 12.1 0.0 5.8 6.7 0.0 3.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Vps52 PF04129.12 EGB07551.1 - 3.6e-47 161.3 0.0 1.1e-46 159.7 0.0 1.8 1 1 0 1 1 1 1 Vps52 / Sac2 family CH PF00307.31 EGB07551.1 - 2.5e-46 156.3 0.0 2.4e-13 50.2 0.0 5.1 4 1 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.32 EGB07551.1 - 1.4e-12 46.2 0.2 2.7e-06 26.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB07551.1 - 3.1e-11 42.3 0.0 0.00021 20.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB07551.1 - 1.3e-09 37.1 0.1 0.00011 21.6 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB07551.1 - 3.5e-09 37.0 0.0 1.6e-08 34.9 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB07551.1 - 1.2e-06 28.2 0.4 0.0015 18.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair Spc7 PF08317.11 EGB07551.1 - 0.0065 15.4 1.3 0.0065 15.4 1.3 2.1 1 1 0 2 2 2 1 Spc7 kinetochore protein Dockerin_1 PF00404.18 EGB07551.1 - 0.019 15.1 0.1 0.06 13.5 0.1 1.9 1 0 0 1 1 1 0 Dockerin type I domain Ntox28 PF15605.6 EGB07551.1 - 0.03 14.5 1.3 1.3 9.3 0.0 3.5 4 0 0 4 4 4 0 Bacterial toxin 28 MRPL52 PF18699.1 EGB07551.1 - 0.12 12.6 0.6 0.31 11.3 0.6 1.6 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Thioredoxin PF00085.20 EGB07552.1 - 1e-16 60.8 0.2 1.1e-16 60.6 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGB07552.1 - 6.3e-07 29.0 0.2 7.8e-07 28.7 0.2 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGB07552.1 - 1.1e-05 25.7 0.1 0.00098 19.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EGB07552.1 - 6.8e-05 22.8 0.1 7.5e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGB07552.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Redoxin MFS_1 PF07690.16 EGB07553.1 - 6.9e-17 61.4 42.0 7e-12 44.9 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGB07553.1 - 4.6e-06 25.4 9.5 0.0099 14.5 2.4 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 EGB07553.1 - 0.027 13.4 14.0 0.1 11.4 2.5 3.0 2 1 0 2 2 2 0 Sugar (and other) transporter MASE3 PF17159.4 EGB07553.1 - 0.073 12.7 1.3 0.1 12.2 0.2 1.8 2 0 0 2 2 2 0 Membrane-associated sensor domain PTR2 PF00854.21 EGB07553.1 - 0.42 9.4 3.3 1.2 7.9 0.5 2.1 2 0 0 2 2 2 0 POT family Fer4_13 PF13370.6 EGB07554.1 - 2.5e-15 56.7 3.2 2.9e-15 56.5 3.2 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EGB07554.1 - 3.9e-09 37.1 5.1 8.3e-09 36.1 5.1 1.5 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 EGB07554.1 - 2.4e-05 24.4 0.6 0.0028 17.7 0.2 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGB07554.1 - 0.0019 18.3 0.4 0.0026 17.8 0.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EGB07554.1 - 0.0044 16.8 6.4 0.025 14.4 1.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EGB07554.1 - 0.009 16.1 0.9 0.009 16.1 0.9 2.0 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_19 PF06902.11 EGB07554.1 - 0.013 15.5 0.2 0.02 15.0 0.2 1.3 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_2 PF12797.7 EGB07554.1 - 0.016 15.3 0.6 0.016 15.3 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 EGB07554.1 - 0.018 15.6 1.4 0.081 13.5 1.4 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain ABC_membrane_2 PF06472.15 EGB07555.1 - 6.1e-51 173.4 6.3 1.6e-50 172.0 6.3 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGB07555.1 - 1e-16 61.7 0.0 2.9e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 EGB07555.1 - 6.8e-11 42.2 2.5 4.2e-10 39.6 2.4 1.9 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_16 PF13191.6 EGB07555.1 - 0.0006 20.2 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGB07555.1 - 0.00074 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EGB07555.1 - 0.0021 17.8 0.0 0.0053 16.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 EGB07555.1 - 0.03 13.4 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain DUF815 PF05673.13 EGB07555.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGB07555.1 - 0.055 13.7 0.1 0.22 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB07555.1 - 0.085 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 EGB07555.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EGB07555.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 EGB07555.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGB07555.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EGB07555.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 EGB07555.1 - 0.18 11.2 0.0 17 4.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 EGB07555.1 - 1.1 8.9 7.2 7.1 6.2 7.2 2.2 1 1 0 1 1 1 0 ABC transporter transmembrane region SnoaL_2 PF12680.7 EGB07556.1 - 8.8e-10 39.1 0.0 1.5e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF3375 PF11855.8 EGB07556.1 - 0.0043 16.1 0.3 0.0062 15.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) DUF4440 PF14534.6 EGB07556.1 - 0.0084 16.5 0.1 0.029 14.8 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) cNMP_binding PF00027.29 EGB07557.1 - 1.7e-43 146.6 6.2 8.8e-07 28.9 0.0 10.7 10 1 0 10 10 10 9 Cyclic nucleotide-binding domain Kinesin PF00225.23 EGB07558.1 - 2.6e-96 322.5 0.0 3e-96 322.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB07558.1 - 1.4e-50 171.1 0.0 2.1e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding nos_propeller_2 PF18793.1 EGB07558.1 - 0.072 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat 2 TPR_2 PF07719.17 EGB07559.1 - 1.4e-21 74.7 15.7 5e-06 26.2 0.1 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGB07559.1 - 9.6e-21 72.7 6.0 3.7e-06 26.5 0.2 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07559.1 - 7.8e-18 63.1 1.2 0.00024 21.0 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB07559.1 - 3.3e-13 50.0 28.7 0.00063 20.3 1.7 7.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB07559.1 - 4.2e-13 49.4 21.5 6.9e-09 35.9 0.0 7.3 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB07559.1 - 3.7e-11 42.2 7.9 5.4e-05 22.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGB07559.1 - 1.1e-10 41.1 0.5 2.9 8.5 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB07559.1 - 3.8e-09 36.1 0.5 0.15 11.8 0.1 5.2 5 0 0 5 5 5 3 TPR repeat TPR_14 PF13428.6 EGB07559.1 - 9.9e-09 35.3 28.6 0.00086 19.9 0.6 7.9 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07559.1 - 3e-08 34.0 6.6 0.0096 16.4 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGB07559.1 - 7e-07 28.7 2.5 0.004 16.4 0.4 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB07559.1 - 1.7e-05 24.5 20.5 0.0018 18.0 0.2 7.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB07559.1 - 6.6e-05 23.0 0.6 6.6e-05 23.0 0.6 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB07559.1 - 0.001 19.5 7.2 0.59 10.9 0.1 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGB07559.1 - 0.55 10.3 6.5 1.2 9.2 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Dynein_light PF01221.18 EGB07560.1 - 7.8e-19 67.8 0.1 8.3e-19 67.7 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Acetyltransf_1 PF00583.25 EGB07561.1 - 1.3e-12 47.9 0.1 1.8e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGB07561.1 - 9.3e-08 32.4 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGB07561.1 - 9.4e-05 22.4 0.0 0.00043 20.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGB07561.1 - 0.001 19.1 0.1 0.13 12.4 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGB07561.1 - 0.073 12.7 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB07561.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Chloroa_b-bind PF00504.21 EGB07562.1 - 3.8e-28 99.0 0.0 5.2e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Phage_cap_E PF03864.15 EGB07562.1 - 0.062 12.5 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Phage major capsid protein E Rad9 PF04139.13 EGB07563.1 - 5.1e-22 78.5 0.0 1.5e-21 77.0 0.0 1.7 2 0 0 2 2 2 1 Rad9 Sulfotransfer_2 PF03567.14 EGB07563.1 - 0.013 15.4 0.0 0.063 13.2 0.0 2.0 2 1 0 2 2 2 0 Sulfotransferase family Menin PF05053.13 EGB07563.1 - 3.2 6.0 9.3 5.5 5.2 9.3 1.4 1 0 0 1 1 1 0 Menin Vps26 PF03643.15 EGB07564.1 - 9.3e-37 126.5 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGB07564.1 - 1.6e-05 25.0 0.0 5.5e-05 23.3 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CAMSAP_CKK PF08683.11 EGB07565.1 - 2.6e-21 76.0 0.0 4.3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated LRR_6 PF13516.6 EGB07566.1 - 8.9e-15 53.4 11.0 0.11 12.6 0.3 10.8 12 0 0 12 12 12 4 Leucine Rich repeat LRR_4 PF12799.7 EGB07566.1 - 0.046 14.2 0.1 10 6.7 0.0 4.6 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB07566.1 - 0.23 11.3 7.5 11 5.9 0.3 5.4 8 1 0 8 8 8 0 Leucine rich repeat Aminotran_1_2 PF00155.21 EGB07567.1 - 3.6e-56 190.9 0.0 4.1e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGB07567.1 - 4.8e-06 25.8 0.0 8.1e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGB07567.1 - 0.0045 15.6 0.0 0.0068 15.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 EGB07567.1 - 0.18 10.5 0.0 0.5 9.1 0.0 1.7 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Mob_synth_C PF06463.13 EGB07568.1 - 2.6e-30 105.0 0.0 4.1e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGB07568.1 - 1.8e-27 96.8 0.0 2.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGB07568.1 - 6.1e-05 23.3 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain LIAS_N PF16881.5 EGB07568.1 - 0.0091 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Fer4_14 PF13394.6 EGB07568.1 - 0.047 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Sulfatase PF00884.23 EGB07569.1 - 7.6e-62 209.5 0.0 8.6e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Sulfatase 5-FTHF_cyc-lig PF01812.20 EGB07571.1 - 2.5e-21 76.4 0.0 3.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Radical_SAM_C PF16199.5 EGB07572.1 - 4e-19 68.4 0.0 6.7e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGB07572.1 - 7.6e-16 58.9 0.0 1.8e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGB07572.1 - 2.5e-06 27.7 0.2 8.5e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGB07572.1 - 8.8e-05 22.5 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 EGB07574.1 - 6.3e-05 22.7 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2510 PF10708.9 EGB07574.1 - 0.003 17.3 0.3 0.007 16.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2510) RRM_occluded PF16842.5 EGB07574.1 - 0.0036 17.1 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Phage_GP20 PF06810.11 EGB07575.1 - 0.0079 16.0 2.5 0.0093 15.8 2.5 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Prefoldin PF02996.17 EGB07575.1 - 0.078 12.9 4.2 5 7.1 1.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit Nucleoporin_FG2 PF15967.5 EGB07575.1 - 0.28 9.6 0.2 0.32 9.5 0.2 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region Sulfotransfer_3 PF13469.6 EGB07576.1 - 1.8e-06 28.5 0.2 0.024 15.0 0.0 3.3 2 1 0 3 3 3 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB07576.1 - 1.7e-05 24.4 0.0 0.00036 20.1 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase domain acVLRF1 PF18859.1 EGB07576.1 - 0.025 14.9 1.3 3.4 8.0 0.1 2.7 3 0 0 3 3 3 0 Actinobacteria/chloroflexi VLRF1 release factor Peptidase_M1 PF01433.20 EGB07580.1 - 7e-80 267.7 0.2 1.1e-79 267.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGB07580.1 - 5.7e-63 213.4 1.3 6.9e-63 213.1 0.3 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGB07580.1 - 6.7e-47 160.1 0.0 9.5e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Sulfatase PF00884.23 EGB07581.1 - 4.5e-52 177.4 0.1 7.4e-52 176.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase PDT PF00800.18 EGB07582.1 - 4.4e-55 186.3 0.0 5.8e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EGB07582.1 - 3.8e-06 26.6 0.0 8.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain DUF3445 PF11927.8 EGB07583.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) PDZ_6 PF17820.1 EGB07584.1 - 3.4e-05 23.6 0.1 0.00013 21.7 0.0 2.1 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.6 EGB07584.1 - 4.7e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 EGB07584.1 - 0.00012 22.5 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 EGB07584.1 - 0.00035 20.1 0.0 0.0045 16.6 0.0 2.3 2 0 0 2 2 2 1 SH3 domain Tricorn_PDZ PF14685.6 EGB07584.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain UBA PF00627.31 EGB07584.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.2 2 0 0 2 2 2 0 UBA/TS-N domain 2OG-FeII_Oxy_3 PF13640.6 EGB07585.1 - 9.3e-05 23.2 0.3 0.00019 22.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RabGAP-TBC PF00566.18 EGB07586.1 - 4.7e-48 163.7 0.0 5.8e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase_Tyr PF07714.17 EGB07586.1 - 0.066 12.5 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PqiA PF04403.13 EGB07587.1 - 7.9e-08 32.3 11.3 5.2e-07 29.6 0.9 2.6 2 0 0 2 2 2 2 Paraquat-inducible protein A U-box PF04564.15 EGB07588.1 - 5.8e-10 39.2 0.0 2e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 EGB07588.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pantoate_ligase PF02569.15 EGB07589.1 - 1.8e-92 309.3 0.0 2.2e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Aldo_ket_red PF00248.21 EGB07590.1 - 2.6e-23 82.7 0.0 2.4e-21 76.2 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family ATPgrasp_N PF18130.1 EGB07590.1 - 0.94 10.1 4.8 0.77 10.3 1.6 2.5 3 1 1 4 4 4 0 ATP-grasp N-terminal domain zf-TRAF PF02176.18 EGB07595.1 - 1e-20 74.2 11.6 1.6e-13 51.1 3.5 2.1 1 1 1 2 2 2 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGB07595.1 - 0.0043 17.5 11.2 0.023 15.1 6.7 2.6 1 1 1 2 2 2 1 TRAF-like zinc-finger DM PF00751.18 EGB07595.1 - 0.0053 16.6 7.9 0.097 12.6 0.4 2.5 2 0 0 2 2 2 2 DM DNA binding domain zf-ACC PF17848.1 EGB07595.1 - 0.012 15.6 2.5 4.2 7.5 0.0 3.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 EGB07595.1 - 0.017 14.7 2.5 3 7.5 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TRAF6_Z2 PF18048.1 EGB07595.1 - 0.13 12.4 3.1 2.4 8.3 0.0 3.1 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-CCHC PF00098.23 EGB07595.1 - 0.39 10.9 5.0 8.6 6.6 0.1 3.5 3 0 0 3 3 3 0 Zinc knuckle Sina PF03145.16 EGB07595.1 - 0.66 9.9 10.4 4.9 7.1 4.4 2.9 1 1 2 3 3 3 0 Seven in absentia protein family Gly_acyl_tr_C PF08444.10 EGB07596.1 - 0.077 13.2 0.2 20 5.5 0.0 2.7 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF4752 PF15944.5 EGB07596.1 - 0.35 10.9 2.4 6.4 6.9 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) Sel1 PF08238.12 EGB07597.1 - 8.7e-17 61.2 7.8 5.7e-06 26.8 0.1 4.7 4 0 0 4 4 4 3 Sel1 repeat zf-MYND PF01753.18 EGB07597.1 - 1.9e-08 34.2 11.7 1.9e-08 34.2 11.7 2.6 2 0 0 2 2 2 1 MYND finger CAP_N PF01213.19 EGB07597.1 - 0.4 10.1 4.3 0.69 9.3 4.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal C2 PF00168.30 EGB07598.1 - 3.2e-92 303.6 0.0 7.3e-16 58.3 0.0 6.5 6 0 0 6 6 6 6 C2 domain Thioredoxin_8 PF13905.6 EGB07598.1 - 1.8e-13 50.6 0.0 3.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like PHD PF00628.29 EGB07598.1 - 7.1e-07 29.0 6.5 1.7e-06 27.8 6.5 1.7 1 0 0 1 1 1 1 PHD-finger Pkinase_Tyr PF07714.17 EGB07598.1 - 0.00021 20.6 0.0 0.0012 18.2 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGB07598.1 - 0.00043 19.7 0.0 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain zf-HC5HC2H PF13771.6 EGB07598.1 - 0.0017 18.5 1.7 0.0038 17.4 1.7 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Ank_2 PF12796.7 EGB07598.1 - 0.0023 18.5 0.0 0.0061 17.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB07598.1 - 0.0031 18.1 0.0 0.0093 16.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB07598.1 - 0.0094 16.4 0.0 1.7 9.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat TPR_12 PF13424.6 EGB07598.1 - 0.02 15.2 1.5 0.092 13.1 1.5 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_5 PF13857.6 EGB07598.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB07598.1 - 0.15 12.7 0.0 2.3 9.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat 2OG-FeII_Oxy PF03171.20 EGB07599.1 - 7.1e-06 26.5 0.0 2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EGB07599.1 - 0.00013 22.3 0.0 0.091 13.0 0.0 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EGB07599.1 - 0.00019 20.3 0.0 0.00061 18.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) Sel1 PF08238.12 EGB07602.1 - 1.2e-20 73.4 7.9 1.2e-07 32.2 0.1 4.1 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 EGB07602.1 - 0.01 16.4 6.8 0.16 12.7 1.5 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF410 PF04190.13 EGB07602.1 - 0.042 13.6 0.1 0.05 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF410) MIT PF04212.18 EGB07602.1 - 0.11 12.5 0.3 1.3 9.2 0.2 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EGB07602.1 - 7.1 7.0 6.7 9.4 6.6 0.1 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EGB07603.1 - 6.6e-12 45.0 4.2 7.1e-12 44.9 4.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB07603.1 - 1.4e-07 30.7 14.1 1.5e-07 30.7 14.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RGS PF00615.19 EGB07604.1 - 8.5e-07 29.3 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain UQ_con PF00179.26 EGB07605.1 - 3.6e-37 127.1 0.0 4.3e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGB07605.1 - 0.064 13.6 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EGB07605.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 UEV domain DER1 PF04511.15 EGB07606.1 - 2.6e-29 102.5 1.1 3.3e-29 102.2 1.1 1.1 1 0 0 1 1 1 1 Der1-like family DUF3295 PF11702.8 EGB07606.1 - 3.3 7.0 7.1 4.2 6.6 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SDA1 PF05285.12 EGB07606.1 - 3.8 6.8 8.2 5 6.5 8.2 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EGB07606.1 - 5.2 6.1 15.2 6.6 5.8 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.32 EGB07607.1 - 4.2e-58 192.0 10.2 5.6e-08 33.3 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB07607.1 - 1.8e-19 69.8 0.0 0.0077 16.5 0.0 6.3 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB07607.1 - 1.1e-09 37.7 0.1 0.0068 15.4 0.0 4.6 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGB07607.1 - 0.019 13.6 0.0 6.3 5.3 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Palm_thioest PF02089.15 EGB07608.1 - 1.3e-57 195.5 0.0 1.5e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase MMR_HSR1 PF01926.23 EGB07609.1 - 4.8e-17 62.1 0.0 5.6e-16 58.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB07609.1 - 6.3e-06 25.8 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EGB07609.1 - 5.6e-05 22.6 0.0 9.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EGB07609.1 - 0.00052 20.1 0.1 0.012 15.7 0.0 2.3 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EGB07609.1 - 0.023 14.6 0.0 0.41 10.5 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase MeaB PF03308.16 EGB07609.1 - 0.027 13.5 0.3 0.039 12.9 0.3 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1330 PF07045.11 EGB07609.1 - 0.041 14.2 0.3 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) AAA_16 PF13191.6 EGB07609.1 - 0.096 13.1 0.0 0.28 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EGB07609.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Docking PF08990.11 EGB07609.1 - 1.7 8.3 7.8 0.6 9.8 3.8 2.3 2 1 0 2 2 2 0 Erythronolide synthase docking Ead_Ea22 PF13935.6 EGB07611.1 - 0.0039 17.9 5.4 0.012 16.3 5.5 1.7 1 1 0 1 1 1 1 Ead/Ea22-like protein CLAMP PF14769.6 EGB07612.1 - 2.5e-27 95.2 0.0 3.6e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 2OG-FeII_Oxy_3 PF13640.6 EGB07613.1 - 9.3e-07 29.7 0.0 1.5e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GATase PF00117.28 EGB07614.1 - 1.4e-28 100.0 0.0 2.3e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 EGB07614.1 - 3.5e-17 62.2 0.0 6.5e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 EGB07614.1 - 2.3e-05 23.6 0.0 0.0042 16.2 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EGB07614.1 - 2.5e-05 24.1 0.1 0.00024 20.9 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EGB07614.1 - 0.005 15.7 0.0 0.025 13.4 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 EGB07614.1 - 0.017 14.6 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 EGB07614.1 - 0.03 14.4 0.0 0.077 13.0 0.0 1.6 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.21 EGB07614.1 - 0.041 13.5 0.1 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 Asparagine synthase GATase_3 PF07685.14 EGB07614.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DIOX_N PF14226.6 EGB07615.1 - 1.4e-07 32.2 0.0 6.6e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGB07615.1 - 0.00027 21.4 0.0 0.00048 20.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 EGB07616.1 - 1.9e-13 50.8 0.3 7e-11 42.6 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB07616.1 - 2e-09 36.9 1.2 0.28 11.9 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGB07616.1 - 9.5e-09 35.4 1.1 7.4e-05 23.0 0.4 3.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB07616.1 - 8.9e-08 32.5 0.0 0.00047 20.7 0.0 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Cupin_8 PF13621.6 EGB07616.1 - 1.3e-07 31.7 0.0 1.8e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain Ank PF00023.30 EGB07616.1 - 2.9e-05 24.3 5.0 3 8.5 0.1 4.7 5 0 0 5 5 5 3 Ankyrin repeat AAA_28 PF13521.6 EGB07616.1 - 0.0043 17.3 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Sulfotransfer_3 PF13469.6 EGB07616.1 - 0.0044 17.4 0.1 0.019 15.4 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family JmjC PF02373.22 EGB07616.1 - 0.006 17.0 0.0 0.025 15.0 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Sulfotransfer_1 PF00685.27 EGB07616.1 - 0.0083 15.6 0.0 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase domain Sulfatase PF00884.23 EGB07617.1 - 1.2e-47 162.8 0.0 1.7e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB07617.1 - 7.3e-09 35.7 0.2 2.6e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGB07617.1 - 0.17 10.5 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PRP38 PF03371.15 EGB07618.1 - 9.8e-47 159.0 0.0 1.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Na_H_Exchanger PF00999.21 EGB07619.1 - 2e-56 191.5 34.1 2.7e-56 191.0 34.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MBD PF01429.19 EGB07619.1 - 2.1e-07 30.5 0.0 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain Filo_VP35 PF02097.15 EGB07619.1 - 0.011 14.9 0.2 0.018 14.1 0.2 1.2 1 0 0 1 1 1 0 Filoviridae VP35 ubiquitin PF00240.23 EGB07623.1 - 0.0039 16.9 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.20 EGB07623.1 - 0.095 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 UBX domain TPR_1 PF00515.28 EGB07624.1 - 1.8e-16 59.1 27.6 0.00024 20.8 0.0 7.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07624.1 - 1.4e-15 56.1 19.5 0.00014 21.8 0.0 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat ANAPC8 PF04049.13 EGB07624.1 - 7.3e-15 55.3 0.0 3e-14 53.3 0.0 2.0 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 EGB07624.1 - 1.1e-12 47.0 41.8 0.0096 16.0 4.2 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07624.1 - 3e-07 30.8 34.9 0.048 14.2 0.2 7.8 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGB07624.1 - 5.4e-06 26.9 4.5 5.4e-06 26.9 4.5 10.5 7 5 3 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB07624.1 - 5.8e-06 25.9 0.6 5.8e-06 25.9 0.6 5.4 6 0 0 6 6 6 1 TPR repeat ANAPC3 PF12895.7 EGB07624.1 - 1.4e-05 25.2 34.0 0.0024 18.1 3.4 6.5 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGB07624.1 - 0.00023 21.4 1.7 0.00023 21.4 1.7 7.2 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB07624.1 - 0.00027 21.5 1.4 0.0028 18.3 0.4 11.2 8 3 3 11 11 10 5 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 EGB07624.1 - 0.0027 18.6 0.0 0.0096 16.8 0.0 2.0 2 0 0 2 2 1 1 2OG-Fe(II) oxygenase superfamily TPR_7 PF13176.6 EGB07624.1 - 0.01 15.8 29.2 0.049 13.7 0.1 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 EGB07624.1 - 0.021 15.3 0.0 0.05 14.1 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_17 PF13431.6 EGB07624.1 - 0.047 14.1 17.7 1.3 9.6 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB07624.1 - 0.71 9.8 7.5 9.3 6.3 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB07624.1 - 0.78 10.5 0.0 0.78 10.5 0.0 9.0 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGB07624.1 - 5.6 6.1 29.0 0.0073 15.5 8.2 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat LMBR1 PF04791.16 EGB07625.1 - 1.7e-32 113.0 0.0 2.6e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein PH PF00169.29 EGB07625.1 - 3.2e-13 50.1 0.0 1.3e-05 25.7 0.0 2.6 2 0 0 2 2 2 2 PH domain EF-hand_7 PF13499.6 EGB07625.1 - 3.2e-09 37.1 0.0 5.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB07625.1 - 6.7e-08 31.9 0.1 0.0048 16.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB07625.1 - 8.5e-08 31.2 0.0 0.00014 21.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB07625.1 - 1.6e-06 27.9 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair PH_8 PF15409.6 EGB07625.1 - 1.5e-05 25.2 0.0 0.036 14.3 0.0 2.8 2 1 0 2 2 2 2 Pleckstrin homology domain EF-hand_5 PF13202.6 EGB07625.1 - 2.2e-05 23.7 0.3 0.011 15.3 0.0 2.7 2 0 0 2 2 2 2 EF hand COPI_assoc PF08507.10 EGB07625.1 - 0.0012 18.9 0.6 0.0012 18.9 0.6 2.2 2 0 0 2 2 2 1 COPI associated protein PH_11 PF15413.6 EGB07625.1 - 0.0046 17.4 0.0 0.068 13.6 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_hydro_16 PF00722.21 EGB07627.1 - 1.6e-25 89.6 0.0 1.9e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGB07627.1 - 7.6e-07 27.9 0.1 0.00022 19.8 0.5 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) IQ PF00612.27 EGB07628.1 - 0.16 11.8 4.2 0.6 10.0 4.2 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Attacin_N PF03768.15 EGB07628.1 - 0.48 10.6 1.7 12 6.1 1.0 2.6 2 0 0 2 2 2 0 Attacin, N-terminal region Sel1 PF08238.12 EGB07629.1 - 6.1e-41 137.9 42.2 7.8e-08 32.8 0.1 10.8 11 1 0 11 11 11 7 Sel1 repeat Flu_M1_C PF08289.11 EGB07629.1 - 0.0018 18.4 0.1 0.56 10.5 0.0 3.0 3 0 0 3 3 3 1 Influenza Matrix protein (M1) C-terminal domain MIT PF04212.18 EGB07629.1 - 0.2 11.8 7.8 0.58 10.3 1.3 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 EGB07629.1 - 0.24 11.1 12.1 5.8 6.7 3.2 5.2 3 2 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 EGB07629.1 - 3.1 8.2 12.1 3.6 8.0 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07629.1 - 4.7 7.6 29.4 13 6.2 0.1 8.0 7 1 0 8 8 8 0 Tetratricopeptide repeat WD40 PF00400.32 EGB07630.1 - 0.00082 20.1 1.1 0.045 14.6 0.0 3.6 3 1 0 3 3 3 1 WD domain, G-beta repeat PALB2_WD40 PF16756.5 EGB07630.1 - 0.046 12.6 0.2 0.067 12.1 0.2 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain zf-MYND PF01753.18 EGB07631.1 - 3.9e-11 42.9 27.2 6e-06 26.3 4.4 2.8 2 0 0 2 2 2 2 MYND finger Glyco_transf_8 PF01501.20 EGB07631.1 - 1.6e-06 27.9 0.0 5.9e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Cwf_Cwc_15 PF04889.12 EGB07631.1 - 0.039 13.7 11.9 0.09 12.5 11.9 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ORC6 PF05460.13 EGB07631.1 - 0.42 9.8 1.8 0.68 9.1 1.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RNA_pol_3_Rpc31 PF11705.8 EGB07631.1 - 0.75 10.0 12.1 1.5 9.0 12.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 2-oxoacid_dh PF00198.23 EGB07632.1 - 5.6e-77 258.3 0.1 7.3e-77 257.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Glucokinase PF02685.16 EGB07632.1 - 3.4e-76 256.3 0.0 1.4e-75 254.3 0.0 1.9 1 1 0 1 1 1 1 Glucokinase Biotin_lipoyl PF00364.22 EGB07632.1 - 1.1e-20 73.3 4.1 2.2e-20 72.3 4.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGB07632.1 - 3.2e-06 26.9 2.7 0.0034 17.2 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 EGB07632.1 - 0.00032 21.3 5.1 0.0034 18.1 0.4 2.5 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 EGB07632.1 - 0.0061 16.5 0.2 0.016 15.1 0.2 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EGB07632.1 - 0.017 15.0 1.0 0.036 14.0 1.0 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 EGB07632.1 - 0.059 12.6 0.3 0.24 10.6 0.1 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion VPS13_C PF16909.5 EGB07633.1 - 8.8e-44 149.4 1.6 1.1e-36 126.3 0.0 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 EGB07633.1 - 1.1e-35 123.6 0.0 2.8e-35 122.3 0.0 1.7 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EGB07633.1 - 2.7e-22 79.0 0.0 5.5e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 RGS PF00615.19 EGB07633.1 - 4.4e-12 46.3 0.0 8.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain ATG_C PF09333.11 EGB07633.1 - 0.00011 22.5 0.3 0.0005 20.4 0.3 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PH PF00169.29 EGB07633.1 - 0.00048 20.6 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGB07633.1 - 0.034 14.4 0.0 0.085 13.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Aa_trans PF01490.18 EGB07634.1 - 1.4e-13 50.4 5.7 1.4e-12 47.1 5.7 2.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Metallophos PF00149.28 EGB07635.1 - 8.8e-08 32.9 0.0 1.1e-06 29.3 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase WWE PF02825.20 EGB07635.1 - 5.7e-06 26.8 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 WWE domain Metallophos_2 PF12850.7 EGB07635.1 - 0.00015 22.0 0.0 0.009 16.2 0.0 2.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Abhydrolase_2 PF02230.16 EGB07635.1 - 0.00078 19.3 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase SH3_3 PF08239.11 EGB07635.1 - 0.0094 16.2 0.1 0.04 14.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain Agenet PF05641.12 EGB07635.1 - 0.01 16.3 3.8 1.4 9.5 0.1 3.4 3 0 0 3 3 3 0 Agenet domain Abhydrolase_3 PF07859.13 EGB07635.1 - 0.038 13.9 1.1 0.41 10.5 0.7 2.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB07635.1 - 0.051 13.0 0.1 0.6 9.5 0.2 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family LBR_tudor PF09465.10 EGB07635.1 - 0.065 13.0 0.0 0.95 9.3 0.0 2.5 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Hydrolase_4 PF12146.8 EGB07635.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Herpes_UL49_1 PF03117.14 EGB07635.1 - 0.46 9.7 8.1 3.3 6.9 0.1 4.3 5 0 0 5 5 5 0 UL49 family SelR PF01641.18 EGB07636.1 - 2.3e-33 114.8 0.0 2.8e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 SelR domain Epimerase PF01370.21 EGB07637.1 - 5e-09 36.0 0.1 2.6e-06 27.1 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGB07637.1 - 0.00077 18.6 0.1 0.0068 15.5 0.1 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGB07637.1 - 0.0011 18.8 0.2 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGB07637.1 - 0.014 14.8 0.0 0.039 13.3 0.0 1.7 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EGB07637.1 - 0.016 14.7 0.3 0.033 13.6 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 EGB07637.1 - 0.023 13.7 0.0 0.6 9.1 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family OHCU_decarbox PF09349.10 EGB07638.1 - 4.1e-40 137.8 0.1 5.3e-40 137.4 0.1 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Transthyretin PF00576.21 EGB07638.1 - 2.1e-31 108.8 0.0 3.1e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 HIUase/Transthyretin family Lipase_GDSL_2 PF13472.6 EGB07639.1 - 6.3e-05 23.4 0.1 0.00045 20.7 0.1 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB07639.1 - 0.0036 17.3 0.0 0.037 14.0 0.0 2.0 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase UCH PF00443.29 EGB07641.1 - 3.8e-38 131.4 0.0 5.2e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB07641.1 - 6.8e-08 32.5 0.0 7.5e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGB07641.1 - 0.0013 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF21 PF01595.20 EGB07642.1 - 4.3e-33 114.5 0.1 5.8e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGB07642.1 - 6.1e-12 45.8 1.9 7.4e-06 26.3 0.1 2.9 3 0 0 3 3 3 2 CBS domain NAD_binding_11 PF14833.6 EGB07643.1 - 3.6e-38 130.5 0.1 7.4e-38 129.5 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EGB07643.1 - 4.7e-34 117.9 5.4 7.8e-34 117.1 5.4 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGB07643.1 - 2.9e-05 24.6 0.4 0.00014 22.4 0.4 2.3 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGB07643.1 - 0.00019 20.9 0.0 0.00041 19.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EGB07643.1 - 0.00074 19.4 0.8 0.0013 18.6 0.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGB07643.1 - 0.0064 16.5 0.7 3.3 7.7 0.0 2.4 1 1 1 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 EGB07643.1 - 0.025 14.2 2.0 0.039 13.5 0.3 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SWIB PF02201.18 EGB07644.1 - 6.3e-48 160.6 0.0 1.8e-23 82.2 0.0 2.4 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 EGB07644.1 - 0.0004 20.2 0.0 0.0018 18.1 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain ER-remodelling PF14755.6 EGB07644.1 - 0.019 15.3 0.2 0.019 15.3 0.2 2.3 2 0 0 2 2 2 0 Intracellular membrane remodeller RPOL_N PF14700.6 EGB07644.1 - 0.088 12.2 5.0 0.15 11.5 5.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal CPSF100_C PF13299.6 EGB07644.1 - 3.8 7.7 13.2 0.8 9.9 8.7 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal LVIVD PF08309.11 EGB07645.1 - 0.027 13.8 1.4 2.2 7.7 0.3 4.0 5 0 0 5 5 5 0 LVIVD repeat Myb_DNA-binding PF00249.31 EGB07646.1 - 2.4e-14 53.3 0.5 4e-14 52.5 0.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB07646.1 - 0.00037 20.7 0.7 0.00066 19.9 0.7 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB07646.1 - 0.0016 18.3 0.1 0.0027 17.6 0.1 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Cas9_Topo PF17894.1 EGB07646.1 - 0.25 11.4 1.3 0.62 10.2 0.3 2.1 2 1 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 ABC_tran PF00005.27 EGB07647.1 - 1.2e-30 106.8 0.0 1e-15 58.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EGB07647.1 - 8.6e-28 97.2 0.0 1.6e-14 53.9 0.0 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 EGB07647.1 - 5.8e-05 23.0 0.1 0.036 13.9 0.0 3.4 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGB07647.1 - 0.0016 18.9 0.4 0.087 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGB07647.1 - 0.004 17.1 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGB07647.1 - 0.005 16.6 0.9 0.43 10.4 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB07647.1 - 0.0098 16.3 2.1 0.12 12.7 0.2 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EGB07647.1 - 0.037 13.6 3.6 0.44 10.1 0.5 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGB07647.1 - 0.059 13.5 0.1 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGB07647.1 - 0.073 13.3 0.5 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGB07647.1 - 0.52 9.9 2.4 0.72 9.4 0.3 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ILEI PF15711.5 EGB07648.1 - 1.1e-11 45.0 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Interleukin-like EMT inducer Amidohydro_1 PF01979.20 EGB07648.1 - 1.4e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGB07648.1 - 4.7e-05 23.0 0.3 4.7e-05 23.0 0.3 2.7 3 0 0 3 3 3 1 Amidohydrolase family Lectin_C PF00059.21 EGB07649.1 - 5.5e-09 36.7 0.1 1e-08 35.8 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Peptidase_S9 PF00326.21 EGB07649.1 - 0.0008 18.9 0.1 0.021 14.3 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGB07649.1 - 0.0068 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGB07649.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase COesterase PF00135.28 EGB07649.1 - 0.034 13.0 0.2 0.82 8.5 0.0 2.3 2 0 0 2 2 2 0 Carboxylesterase family DUF599 PF04654.12 EGB07649.1 - 0.049 13.0 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Thioredoxin PF00085.20 EGB07649.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin RIB43A PF05914.12 EGB07650.1 - 4.8e-25 88.1 43.3 8.1e-25 87.4 43.3 1.3 1 0 0 1 1 1 1 RIB43A Phytochelatin PF05023.14 EGB07651.1 - 9.1e-82 273.4 0.0 1.1e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 EGB07651.1 - 0.00041 20.9 0.0 0.75 10.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family DHHC PF01529.20 EGB07652.1 - 2.2e-10 40.8 10.7 4.1e-10 39.9 10.7 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase NMO PF03060.15 EGB07653.1 - 1.1e-19 71.0 2.9 4.7e-19 69.0 1.4 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 EGB07653.1 - 0.0074 15.3 5.9 0.013 14.5 5.6 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGB07653.1 - 0.056 12.4 2.8 0.63 9.0 2.8 2.2 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Pkinase PF00069.25 EGB07654.1 - 1.8e-55 188.1 0.0 2.1e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07654.1 - 5.9e-34 117.5 0.0 8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB07654.1 - 0.00015 20.7 0.0 0.00022 20.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB07654.1 - 0.0035 16.7 0.0 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGB07654.1 - 0.016 15.1 0.1 0.28 11.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGB07654.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RabGAP-TBC PF00566.18 EGB07655.1 - 8.8e-14 51.7 0.2 1.7e-12 47.5 0.8 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_8 PF13833.6 EGB07656.1 - 5.8e-07 29.3 0.0 0.064 13.1 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGB07656.1 - 0.013 15.0 0.1 8.2 6.2 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 EGB07656.1 - 0.017 15.0 0.1 3.9 7.7 0.0 2.9 4 0 0 4 4 4 0 EF-hand domain DUF393 PF04134.12 EGB07657.1 - 8.1e-25 88.4 0.1 1.9e-24 87.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF393 SSF PF00474.17 EGB07657.1 - 2.1e-13 49.9 16.3 1.6e-08 33.8 7.6 2.3 2 0 0 2 2 2 2 Sodium:solute symporter family TPP_enzyme_N PF02776.18 EGB07658.1 - 1.3e-28 99.7 2.6 1.9e-28 99.2 2.6 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain HMG_CoA_synt_N PF01154.17 EGB07659.1 - 3.1e-48 163.9 0.0 3.6e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 EGB07660.1 - 3.1e-22 79.4 7.6 3.4e-22 79.2 7.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ketoacyl-synt PF00109.26 EGB07661.1 - 2.2e-28 99.5 12.5 3.1e-28 99.0 12.5 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB07661.1 - 2.3e-09 37.3 0.2 5.2e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGB07662.1 - 9.1e-32 110.6 10.0 1.6e-31 109.8 10.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB07662.1 - 1.7e-05 24.8 0.6 5.8e-05 23.1 0.6 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB07662.1 - 0.0092 15.4 0.6 0.0092 15.4 0.6 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGB07662.1 - 1.8 8.4 9.3 0.46 10.4 0.8 3.0 3 1 1 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGB07663.1 - 3.9e-38 131.5 5.7 3.9e-38 131.5 5.7 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB07663.1 - 7.7e-11 42.1 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB07663.1 - 0.0044 16.4 0.3 0.0071 15.7 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGB07663.1 - 0.041 13.7 1.0 0.17 11.8 0.3 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 EGB07664.1 - 3.5e-49 167.0 0.0 4.2e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ketoacyl-synt PF00109.26 EGB07665.1 - 6.6e-24 84.9 6.7 7.3e-24 84.7 6.7 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain VCBS PF13517.6 EGB07666.1 - 6.6e-49 164.3 116.8 3.2e-10 40.5 8.4 8.9 3 2 6 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AbfS_sensor PF18225.1 EGB07666.1 - 8.8e-05 22.3 0.0 25 4.9 0.0 6.1 6 0 0 6 6 6 1 Sensor histidine kinase (AbfS) sensor domain WW PF00397.26 EGB07666.1 - 0.0002 21.3 5.3 0.00075 19.5 5.3 2.0 1 1 0 1 1 1 1 WW domain Dockerin_1 PF00404.18 EGB07666.1 - 0.0072 16.5 48.2 0.066 13.4 3.3 8.1 7 1 2 9 9 9 4 Dockerin type I domain F-box PF00646.33 EGB07666.1 - 0.11 12.4 4.1 0.21 11.5 4.1 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EGB07666.1 - 0.78 9.7 5.3 2.5 8.0 5.3 1.8 1 0 0 1 1 1 0 F-box-like DUF3927 PF13064.6 EGB07666.1 - 0.91 9.6 8.6 4.5 7.3 0.3 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3927) EF-hand_1 PF00036.32 EGB07667.1 - 9.2e-18 62.4 7.6 2.4e-05 23.5 0.6 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGB07667.1 - 1.4e-17 63.9 2.5 2e-10 40.9 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB07667.1 - 2.1e-15 55.3 7.0 5.2e-07 29.1 0.0 4.7 3 2 2 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EGB07667.1 - 9.9e-15 54.1 4.3 5.6e-08 32.5 0.2 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB07667.1 - 4.2e-13 48.1 9.7 0.00014 21.2 0.1 3.9 3 1 1 4 4 4 3 EF hand EF-hand_9 PF14658.6 EGB07667.1 - 4.6e-09 36.5 0.1 1.7e-06 28.2 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 EGB07667.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) NA37 PF04245.13 EGB07667.1 - 0.011 15.3 0.4 0.013 15.0 0.4 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein KAR9 PF08580.10 EGB07667.1 - 0.054 12.0 0.7 0.068 11.7 0.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 EF-hand_11 PF08976.11 EGB07667.1 - 0.14 13.1 0.5 0.35 11.8 0.2 1.7 2 0 0 2 2 2 0 EF-hand domain DTHCT PF08070.11 EGB07668.1 - 0.021 15.5 0.3 0.026 15.2 0.3 1.2 1 0 0 1 1 1 0 DTHCT (NUC029) region Fructosamin_kin PF03881.14 EGB07669.1 - 5.2e-69 232.6 0.0 6.3e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EGB07669.1 - 6.5e-08 32.8 0.0 8.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_25 PF13649.6 EGB07670.1 - 8.5e-14 52.0 0.2 1.3e-13 51.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB07670.1 - 8.8e-13 48.7 0.4 1.4e-12 48.0 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB07670.1 - 2.9e-12 47.2 0.0 4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB07670.1 - 7e-09 35.7 0.0 9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB07670.1 - 1e-07 31.9 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGB07670.1 - 1.8e-07 31.0 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 EGB07670.1 - 0.0033 17.4 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB07670.1 - 0.012 14.9 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EGB07670.1 - 0.023 13.9 0.0 0.051 12.8 0.0 1.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 EGB07670.1 - 0.028 13.4 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AdoMet_MTase PF07757.13 EGB07670.1 - 0.048 14.0 0.0 0.63 10.4 0.0 2.1 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 EGB07670.1 - 0.052 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.14 EGB07670.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EGB07670.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CTP_transf_like PF01467.26 EGB07671.1 - 1.1e-31 110.0 0.0 4.8e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EGB07671.1 - 0.0081 16.1 5.0 2.8 7.8 1.1 3.3 2 1 0 2 2 2 2 FAD synthetase DDE_5 PF13546.6 EGB07671.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease CHAP PF05257.16 EGB07671.1 - 0.058 14.0 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 CHAP domain Abhydrolase_6 PF12697.7 EGB07672.1 - 3.7e-21 76.8 5.7 4.5e-21 76.5 5.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB07672.1 - 5.3e-13 48.8 0.0 1.8e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB07672.1 - 2.8e-11 43.6 0.1 1.8e-10 40.9 0.1 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EGB07672.1 - 1.2e-05 25.1 0.0 3.7e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.16 EGB07672.1 - 0.044 13.4 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ser_hydrolase PF06821.13 EGB07672.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Phosducin PF02114.16 EGB07673.1 - 1.2e-14 53.9 0.0 1.3e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Phosducin ABC_membrane PF00664.23 EGB07674.1 - 5e-43 147.7 14.8 3e-28 99.2 5.2 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGB07674.1 - 4.1e-37 127.8 0.0 3.1e-20 73.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 EGB07674.1 - 3.2e-08 33.2 0.9 0.00019 21.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGB07674.1 - 1.9e-07 31.3 0.1 0.00039 20.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin family SMC_N PF02463.19 EGB07674.1 - 2.3e-07 30.5 0.4 0.31 10.4 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGB07674.1 - 5.9e-07 29.6 0.0 0.1 12.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB07674.1 - 7.6e-07 29.7 3.1 0.00043 20.7 0.2 3.3 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGB07674.1 - 1.4e-05 25.1 0.1 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB07674.1 - 1.5e-05 25.0 0.7 0.024 14.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGB07674.1 - 8.4e-05 22.0 0.2 0.032 13.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SSE PF00437.20 EGB07674.1 - 0.00021 20.5 0.7 0.073 12.1 0.1 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGB07674.1 - 0.00041 20.6 1.8 0.49 10.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_23 PF13476.6 EGB07674.1 - 0.00095 19.7 0.0 2 8.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EGB07674.1 - 0.0015 18.7 0.3 1.4 9.2 0.0 3.7 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EGB07674.1 - 0.0047 17.5 0.3 2.1 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EGB07674.1 - 0.0061 15.6 1.3 0.95 8.4 0.2 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EGB07674.1 - 0.01 16.0 3.7 0.1 12.7 0.2 2.8 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGB07674.1 - 0.015 15.1 0.2 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 EGB07674.1 - 0.035 13.7 4.9 0.76 9.3 0.1 3.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGB07674.1 - 0.043 13.1 0.2 6.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EGB07674.1 - 0.071 12.7 1.7 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EGB07674.1 - 0.08 12.2 0.4 0.4 9.9 0.1 1.9 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 EGB07674.1 - 0.081 12.6 0.0 3.4 7.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 EGB07674.1 - 0.092 11.9 0.1 4 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGB07674.1 - 0.097 12.2 0.1 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EGB07674.1 - 0.16 11.9 0.4 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain GTP_EFTU PF00009.27 EGB07674.1 - 0.23 10.9 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.17 EGB07674.1 - 0.5 10.4 3.3 6 6.9 0.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 EGB07674.1 - 0.54 10.3 1.6 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MA3 PF02847.17 EGB07675.1 - 5.1e-32 110.2 0.0 1.2e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 MA3 domain tRNA-synt_1g PF09334.11 EGB07676.1 - 3e-64 217.2 0.0 2.5e-57 194.4 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGB07676.1 - 2.7e-11 42.4 0.0 3.3e-10 38.9 0.0 2.0 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) PDZ_6 PF17820.1 EGB07676.1 - 0.00067 19.4 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 PDZ domain tRNA-synt_1e PF01406.19 EGB07676.1 - 0.0031 16.9 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 EGB07677.1 - 6e-51 173.3 0.0 6.6e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07677.1 - 1.9e-25 89.6 0.0 2.3e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB07677.1 - 0.00072 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB07677.1 - 0.001 18.0 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB07677.1 - 0.0027 17.0 0.0 0.016 14.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB07677.1 - 0.0032 17.4 2.7 0.31 10.9 1.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Neur_chan_LBD PF02931.23 EGB07679.1 - 2.1e-24 86.2 0.1 3e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 EGB07679.1 - 1.3e-08 35.2 0.1 1e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.32 EGB07679.1 - 9.5e-06 24.8 0.0 0.051 13.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB07679.1 - 3.4e-05 23.1 1.3 0.024 14.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB07679.1 - 0.0005 19.8 0.1 0.74 9.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB07679.1 - 0.0021 17.9 0.3 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EGB07679.1 - 0.016 15.6 0.0 0.59 10.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair FKBP_C PF00254.28 EGB07680.1 - 1.5e-22 79.7 0.0 1.9e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 EGB07680.1 - 3.1e-05 24.8 0.0 7e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LRR_6 PF13516.6 EGB07681.1 - 6.3e-12 44.5 5.7 0.00012 21.8 0.0 4.2 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 EGB07681.1 - 1.6e-06 28.3 0.1 0.1 13.0 0.1 3.1 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB07681.1 - 6.7e-05 22.6 1.5 0.89 9.4 0.1 3.3 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EGB07681.1 - 0.015 15.7 0.0 21 6.2 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat DUF3197 PF11432.8 EGB07681.1 - 0.095 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Glyco_transf_90 PF05686.12 EGB07682.1 - 3.8e-06 26.1 0.0 0.012 14.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 90 Sulfotransfer_3 PF13469.6 EGB07682.1 - 0.00032 21.2 0.0 0.00064 20.2 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Glyco_trans_1_2 PF13524.6 EGB07682.1 - 3.9 7.9 11.8 0.36 11.2 0.8 3.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 Beta_helix PF13229.6 EGB07683.1 - 2.6e-06 27.4 1.2 1.6e-05 24.8 1.2 2.1 1 1 0 1 1 1 1 Right handed beta helix region Ogr_Delta PF04606.12 EGB07685.1 - 0.18 11.8 5.3 5.6 7.0 0.5 2.7 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Epimerase PF01370.21 EGB07686.1 - 8.2e-11 41.8 0.0 1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB07686.1 - 4e-06 26.9 0.0 5.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGB07686.1 - 8.1e-06 25.2 0.1 0.076 12.2 0.1 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EGB07686.1 - 5.2e-05 22.4 0.0 6.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGB07686.1 - 0.051 13.0 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGB07686.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Solute_trans_a PF03619.16 EGB07687.1 - 2.6e-70 237.0 0.4 3.5e-70 236.6 0.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha FMO-like PF00743.19 EGB07688.1 - 1.6e-12 46.7 0.2 1.7e-12 46.5 0.2 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EGB07688.1 - 4e-10 39.8 0.0 5.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGB07688.1 - 3.3e-08 33.2 0.1 5.5e-08 32.4 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB07688.1 - 3.8e-07 29.6 0.1 4.6e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EGB07688.1 - 8.5e-07 28.5 0.1 1.1e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB07688.1 - 9.3e-07 28.4 0.0 9.3e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB07688.1 - 1.1e-05 24.3 0.2 1.4e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EGB07688.1 - 3.2e-05 23.4 0.0 3.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EGB07688.1 - 8.2e-05 21.9 0.1 0.00011 21.5 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EGB07688.1 - 9.3e-05 21.9 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB07688.1 - 0.00072 20.1 0.2 0.0013 19.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB07688.1 - 0.0037 16.9 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 EGB07688.1 - 0.008 16.4 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Lycopene_cycl PF05834.12 EGB07688.1 - 0.01 14.9 0.2 0.013 14.6 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 EGB07688.1 - 0.01 15.4 0.2 0.014 14.9 0.2 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 EGB07688.1 - 0.015 14.2 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EGB07688.1 - 0.015 15.7 0.0 0.018 15.5 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 EGB07688.1 - 0.021 13.9 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EGB07688.1 - 0.024 14.6 0.0 0.031 14.3 0.0 1.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 EGB07688.1 - 0.033 13.7 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EGB07688.1 - 0.037 13.3 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EGB07688.1 - 0.085 12.5 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 EGB07688.1 - 0.13 11.8 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ribosomal_L7Ae PF01248.26 EGB07690.1 - 1.8e-26 91.7 0.3 2.2e-26 91.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peptidase_M3 PF01432.20 EGB07691.1 - 1.6e-15 57.3 0.0 8.2e-14 51.7 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 EGB07691.1 - 0.00017 20.3 0.1 0.00024 19.9 0.1 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M32 PF02074.15 EGB07691.1 - 0.096 11.4 0.0 2.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase Peptidase_M3_N PF08439.10 EGB07691.1 - 0.23 11.7 0.8 11 6.3 0.0 3.3 4 0 0 4 4 4 0 Oligopeptidase F WD40 PF00400.32 EGB07692.1 - 3.3e-28 97.3 3.4 5.2e-05 23.9 0.7 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB07692.1 - 5.9e-15 55.3 0.0 0.00029 21.1 0.0 4.9 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB07692.1 - 0.0034 16.1 0.2 0.4 9.3 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ank_4 PF13637.6 EGB07694.1 - 2.9e-20 72.3 0.9 5.1e-10 39.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB07694.1 - 3.9e-13 48.3 0.0 7.8e-05 22.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EGB07694.1 - 5.7e-13 49.3 0.0 7.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB07694.1 - 2.8e-12 46.6 0.1 4.7e-08 33.2 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB07694.1 - 6.8e-10 38.9 0.2 2.8e-05 24.4 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Polyketide_cyc2 PF10604.9 EGB07695.1 - 2.7e-08 34.2 0.1 4.1e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EGB07695.1 - 1.2e-06 28.7 0.0 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PCIF1_WW PF12237.8 EGB07697.1 - 1.1e-51 174.9 0.0 2e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain DUF1581 PF07619.11 EGB07697.1 - 0.11 12.6 0.1 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) Tyrosinase PF00264.20 EGB07698.1 - 6.8e-12 46.2 0.6 4.1e-11 43.6 0.7 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Peptidase_C97 PF05903.14 EGB07699.1 - 9.1e-25 87.2 0.0 1.1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain NUDIX PF00293.28 EGB07700.1 - 2.1e-17 63.4 0.0 3.2e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SQS_PSY PF00494.19 EGB07701.1 - 4.6e-35 121.4 0.0 5.3e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Sugar_tr PF00083.24 EGB07702.1 - 4e-71 240.2 26.4 4.7e-71 240.0 26.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB07702.1 - 5.6e-11 42.0 50.0 1.6e-10 40.5 26.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3487 PF11990.8 EGB07702.1 - 8.2 6.4 16.5 0.083 12.8 0.9 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3487) Pyridoxal_deC PF00282.19 EGB07704.1 - 3.9e-20 71.9 0.0 5.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGB07704.1 - 5.6e-08 32.1 0.0 1e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGB07704.1 - 1.1e-06 28.2 0.1 1.6e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGB07704.1 - 0.016 13.7 0.0 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pro_isomerase PF00160.21 EGB07705.1 - 1.2e-21 77.6 0.0 2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGB07705.1 - 3.7e-14 52.3 0.1 5.9e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FA_hydroxylase PF04116.13 EGB07706.1 - 5.1e-16 59.2 18.8 5.1e-16 59.2 18.8 1.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily EGF_2 PF07974.13 EGB07708.1 - 1e-14 54.6 48.1 9.6e-07 29.1 6.1 5.8 5 1 0 5 5 5 4 EGF-like domain EGF PF00008.27 EGB07708.1 - 3.8e-05 23.9 12.6 0.0014 18.9 2.1 5.8 8 0 0 8 8 8 4 EGF-like domain Laminin_EGF PF00053.24 EGB07708.1 - 0.033 14.3 11.5 0.033 14.3 11.5 4.6 3 1 1 4 4 4 0 Laminin EGF domain Glyco_hydro_3_C PF01915.22 EGB07709.1 - 1.4e-41 142.7 0.0 2.3e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGB07709.1 - 5.3e-37 127.9 0.0 1.8e-34 119.6 0.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGB07709.1 - 2.9e-13 49.7 1.0 7.1e-13 48.5 1.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Rep_fac_C PF08542.11 EGB07710.1 - 1.1e-18 67.4 0.0 2.6e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGB07710.1 - 9.5e-14 51.9 0.1 1.4e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGB07710.1 - 8.8e-10 38.6 0.0 4e-08 33.2 0.1 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EGB07710.1 - 3.7e-06 27.4 0.0 8.4e-05 23.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGB07710.1 - 4.6e-06 26.7 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGB07710.1 - 3e-05 23.5 0.1 0.00028 20.3 0.1 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EGB07710.1 - 8.1e-05 22.9 0.2 0.018 15.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB07710.1 - 0.00025 20.8 0.2 0.00081 19.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB07710.1 - 0.00069 20.0 0.6 0.0039 17.5 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB07710.1 - 0.002 17.7 0.0 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGB07710.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGB07710.1 - 0.0024 17.7 0.0 0.0056 16.4 0.0 1.6 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EGB07710.1 - 0.0027 18.3 0.1 0.0062 17.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EGB07710.1 - 0.0032 17.2 0.0 0.0095 15.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGB07710.1 - 0.0048 16.9 0.0 0.016 15.2 0.1 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB07710.1 - 0.005 16.7 0.1 0.0088 15.9 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 EGB07710.1 - 0.0063 16.8 0.1 0.022 15.1 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_7 PF12775.7 EGB07710.1 - 0.0075 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGB07710.1 - 0.008 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EGB07710.1 - 0.0089 15.0 0.0 0.023 13.7 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 EGB07710.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.29 EGB07710.1 - 0.016 15.0 0.1 1.8 8.3 0.0 2.6 1 1 2 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 EGB07710.1 - 0.018 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGB07710.1 - 0.026 13.6 0.2 0.057 12.5 0.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 EGB07710.1 - 0.028 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ResIII PF04851.15 EGB07710.1 - 0.037 14.0 0.0 1.2 9.1 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 EGB07710.1 - 0.039 13.4 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 EGB07710.1 - 0.043 14.2 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EGB07710.1 - 0.064 13.2 0.1 0.31 11.0 0.1 2.0 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 EGB07710.1 - 0.084 13.4 0.0 0.2 12.2 0.0 1.6 2 0 0 2 2 1 0 ABC transporter KTI12 PF08433.10 EGB07710.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PhoH PF02562.16 EGB07710.1 - 0.16 11.4 0.7 4.4 6.7 0.0 2.3 1 1 1 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 EGB07710.1 - 0.19 11.0 0.1 1.3 8.1 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HSF_DNA-bind PF00447.17 EGB07711.1 - 4.1e-15 56.2 0.0 6.7e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding SAP PF02037.27 EGB07712.1 - 2.1e-08 33.7 0.1 0.00036 20.2 0.0 2.6 2 0 0 2 2 2 2 SAP domain STI1 PF17830.1 EGB07712.1 - 7.7e-06 25.7 2.6 4.8e-05 23.2 2.6 2.1 1 1 0 1 1 1 1 STI1 domain KH_1 PF00013.29 EGB07712.1 - 1.6e-05 24.6 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KH domain V_ATPase_prox PF18274.1 EGB07712.1 - 0.016 15.2 0.8 2.8 8.0 0.1 2.5 2 0 0 2 2 2 0 Vacuolar ATPase Subunit I N-terminal proximal lobe KH_4 PF13083.6 EGB07712.1 - 0.068 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 KH domain MitMem_reg PF13012.6 EGB07712.1 - 0.18 12.2 0.0 17 5.8 0.0 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Sod_Fe_N PF00081.22 EGB07713.1 - 5e-34 116.6 0.2 8.1e-34 115.9 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 EGB07713.1 - 1.8e-33 114.7 0.0 3.1e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Ribosomal_L37e PF01907.19 EGB07714.1 - 3.2e-26 91.2 10.6 6e-26 90.4 10.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DUF35_N PF12172.8 EGB07714.1 - 0.0083 16.0 2.6 0.016 15.0 2.6 1.5 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 EGB07714.1 - 0.015 15.3 1.1 0.024 14.6 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C2HC5 PF06221.13 EGB07714.1 - 0.032 14.2 0.8 0.048 13.7 0.8 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type SelR PF01641.18 EGB07714.1 - 0.033 14.3 0.4 0.037 14.1 0.4 1.3 1 0 0 1 1 1 0 SelR domain zf-ribbon_3 PF13248.6 EGB07714.1 - 0.12 11.8 3.8 0.38 10.2 3.7 1.8 1 1 1 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 EGB07714.1 - 0.16 12.1 4.9 0.18 12.0 4.9 1.4 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 EGB07714.1 - 0.19 11.5 4.2 7.6 6.4 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 EGB07714.1 - 0.63 9.6 4.0 5.9 6.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-ribbon DUF1258 PF06869.12 EGB07714.1 - 0.82 9.1 3.7 0.92 8.9 3.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) YhfH PF14149.6 EGB07714.1 - 2 8.5 5.1 4.3 7.4 0.3 2.3 1 1 1 2 2 2 0 YhfH-like protein DUF2688 PF10892.8 EGB07714.1 - 7.9 6.0 7.8 2.1 7.9 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) TLC PF03219.14 EGB07715.1 - 8.6e-182 605.2 6.6 1e-181 605.0 6.6 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter ATP_bind_1 PF03029.17 EGB07716.1 - 7.1e-66 222.4 0.0 8.9e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein cobW PF02492.19 EGB07716.1 - 9.8e-06 25.3 0.4 0.00013 21.6 0.4 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGB07716.1 - 2.8e-05 24.3 0.1 0.00027 21.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 EGB07716.1 - 5.4e-05 22.3 0.0 0.43 9.5 0.0 3.1 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 EGB07716.1 - 6e-05 22.9 0.0 0.086 12.6 0.0 2.2 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 EGB07716.1 - 0.00012 21.8 0.0 0.028 14.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRPRB PF09439.10 EGB07716.1 - 0.0002 20.9 0.0 0.031 13.7 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGB07716.1 - 0.00022 21.3 0.0 0.0042 17.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB07716.1 - 0.00023 20.7 0.0 0.12 11.9 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EGB07716.1 - 0.0006 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EGB07716.1 - 0.0033 17.2 0.0 0.57 9.9 0.0 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_31 PF13614.6 EGB07716.1 - 0.0039 17.1 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGB07716.1 - 0.005 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 EGB07716.1 - 0.0084 15.7 0.7 0.057 13.0 0.0 2.5 2 2 1 3 3 3 1 AAA domain NTPase_1 PF03266.15 EGB07716.1 - 0.013 15.4 0.0 0.1 12.5 0.0 2.2 1 1 0 1 1 1 0 NTPase AAA_16 PF13191.6 EGB07716.1 - 0.013 15.9 0.1 0.031 14.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EGB07716.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain FeoB_N PF02421.18 EGB07716.1 - 0.029 13.9 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 EGB07716.1 - 0.065 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MipZ PF09140.11 EGB07716.1 - 0.065 12.5 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ ATPase PF06745.13 EGB07716.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Roc PF08477.13 EGB07716.1 - 0.08 13.2 0.0 0.82 9.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EGB07716.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 EGB07716.1 - 0.097 11.8 0.0 10 5.2 0.0 2.5 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_22 PF13401.6 EGB07716.1 - 0.12 12.6 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 EGB07716.1 - 0.28 11.7 0.0 0.46 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.6 EGB07717.1 - 2.1e-32 112.8 0.0 4.7e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain aGPT-Pplase1 PF18723.1 EGB07717.1 - 2.9e-30 105.7 0.0 4.7e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Reprolysin_4 PF13583.6 EGB07717.1 - 7.8e-06 25.7 0.3 1.5e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EGB07717.1 - 8.7e-06 26.0 0.2 1.9e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EGB07717.1 - 5.2e-05 23.8 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Cupin_4 PF08007.12 EGB07717.1 - 0.00094 18.7 0.0 0.003 17.1 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB07717.1 - 0.003 17.2 0.4 0.034 13.8 0.0 2.6 2 0 0 2 2 2 1 Cupin domain Peptidase_M66 PF10462.9 EGB07717.1 - 0.0038 16.2 0.2 0.0085 15.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.6 EGB07717.1 - 0.012 15.6 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like HemolysinCabind PF00353.19 EGB07717.1 - 0.46 10.5 33.7 1.4 9.0 2.3 5.5 5 0 0 5 5 5 0 RTX calcium-binding nonapeptide repeat (4 copies) U-box PF04564.15 EGB07718.1 - 8.3e-10 38.7 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain TRP PF06011.12 EGB07718.1 - 0.0043 15.9 0.1 0.0072 15.1 0.1 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel zf-Nse PF11789.8 EGB07718.1 - 0.033 14.0 0.3 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DXP_reductoisom PF02670.16 EGB07719.1 - 1.6e-40 138.8 2.8 2.8e-40 138.0 2.8 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 EGB07719.1 - 7.3e-35 119.7 0.0 3.2e-34 117.7 0.0 1.9 2 0 0 2 2 2 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 EGB07719.1 - 1.8e-34 117.8 0.0 3e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Alg6_Alg8 PF03155.15 EGB07720.1 - 1.1e-55 189.5 3.6 6.5e-47 160.6 0.1 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family Lebercilin PF15619.6 EGB07721.1 - 2e-08 34.1 3.8 2e-08 34.1 3.8 3.3 3 1 0 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease RasGAP_C PF03836.15 EGB07721.1 - 0.36 11.0 6.4 2.5 8.3 0.0 3.3 2 1 1 3 3 3 0 RasGAP C-terminus Bacillus_HBL PF05791.11 EGB07721.1 - 0.48 10.2 2.8 1.4 8.8 2.8 1.8 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Cnn_1N PF07989.11 EGB07721.1 - 1.1 9.5 17.4 0.24 11.6 0.3 4.5 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 Lectin_N PF03954.14 EGB07721.1 - 4.3 7.1 12.8 0.38 10.5 2.7 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain PP2C PF00481.21 EGB07722.1 - 4.2e-47 160.9 1.5 8e-43 146.9 0.5 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EGB07722.1 - 4.7e-05 23.4 0.2 0.18 11.7 0.1 2.5 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) POTRA_1 PF08478.10 EGB07722.1 - 0.021 15.1 0.3 0.11 12.8 0.3 2.1 1 1 0 1 1 1 0 POTRA domain, FtsQ-type Aa_trans PF01490.18 EGB07723.1 - 3e-18 65.7 1.9 4.2e-18 65.3 1.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein cobW PF02492.19 EGB07724.1 - 2.5e-58 196.6 1.3 3.2e-58 196.2 1.3 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB07724.1 - 8e-18 64.2 0.0 1.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGB07724.1 - 0.0004 20.3 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB07724.1 - 0.0011 19.4 0.3 0.013 15.9 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 EGB07724.1 - 0.0035 16.9 6.0 0.0086 15.6 4.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain T2SSE PF00437.20 EGB07724.1 - 0.0099 15.0 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 EGB07724.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGB07724.1 - 0.031 14.5 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EGB07724.1 - 0.032 13.4 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.10 EGB07724.1 - 0.053 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EGB07724.1 - 0.056 13.2 0.4 0.12 12.2 0.1 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EGB07724.1 - 0.064 13.8 0.2 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGB07724.1 - 0.079 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGB07724.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB07724.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EGB07724.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB07724.1 - 0.15 12.3 0.1 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGB07724.1 - 0.62 10.5 3.2 1.1 9.7 3.2 1.7 1 1 0 1 1 1 0 AAA domain SF3b1 PF08920.10 EGB07725.1 - 2.3e-36 124.9 1.5 2.3e-36 124.9 1.5 5.2 1 1 3 4 4 4 1 Splicing factor 3B subunit 1 HEAT PF02985.22 EGB07725.1 - 4.4e-08 32.7 12.0 2.8 8.5 0.1 9.5 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 EGB07725.1 - 6.7e-07 29.6 8.6 0.028 14.8 0.0 6.9 4 2 4 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 EGB07725.1 - 2.2e-06 28.0 8.0 0.27 11.8 0.0 7.0 7 1 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 EGB07725.1 - 0.0027 17.3 0.3 0.43 10.1 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 EGB07725.1 - 0.0064 17.1 1.9 1.4 9.6 0.0 4.9 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EGB07725.1 - 0.0081 14.8 1.2 0.1 11.2 0.0 3.0 2 2 0 2 2 2 1 Adaptin N terminal region NUC173 PF08161.12 EGB07725.1 - 0.027 14.1 0.8 1.4 8.6 0.0 4.0 5 1 0 5 5 5 0 NUC173 domain DUF1428 PF07237.11 EGB07725.1 - 0.027 14.7 0.3 0.51 10.6 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) DUF2384 PF09722.10 EGB07725.1 - 0.32 11.1 3.2 28 4.9 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) Rad60-SLD PF11976.8 EGB07726.1 - 7e-20 70.6 0.3 7.8e-20 70.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGB07726.1 - 1.2e-10 40.9 0.0 1.4e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Plug PF07715.15 EGB07726.1 - 0.042 14.4 0.0 0.042 14.4 0.0 1.1 1 0 0 1 1 1 0 TonB-dependent Receptor Plug Domain Chloroa_b-bind PF00504.21 EGB07728.1 - 5.3e-41 140.8 0.5 7.1e-41 140.4 0.1 1.4 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Abhydrolase_1 PF00561.20 EGB07729.1 - 4.8e-08 33.0 0.0 1.9e-07 31.0 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB07729.1 - 4.4e-05 22.9 0.1 0.0001 21.6 0.1 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 HHH_3 PF12836.7 EGB07729.1 - 0.00037 20.7 0.0 0.00084 19.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Nramp PF01566.18 EGB07730.1 - 4.4e-92 308.8 13.0 5.6e-92 308.5 13.0 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein FH2 PF02181.23 EGB07731.1 - 1.2e-43 149.7 0.0 3.3e-43 148.2 0.0 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 EGB07731.1 - 2.4e-33 115.7 4.3 9.9e-13 48.8 0.9 7.1 8 1 0 8 8 8 3 Subunit CCDC53 of WASH complex Drf_GBD PF06371.13 EGB07731.1 - 7.9e-15 54.9 0.0 3.1e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGB07731.1 - 0.0064 16.1 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 2 Diaphanous FH3 Domain Nucleoside_tran PF01733.18 EGB07732.1 - 9.9e-36 123.7 0.0 2e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoside transporter Virul_fac_BrkB PF03631.15 EGB07733.1 - 0.025 14.2 0.3 0.044 13.4 0.3 1.4 1 0 0 1 1 1 0 Virulence factor BrkB Ion_trans PF00520.31 EGB07734.1 - 9.7e-116 385.2 32.0 1.4e-35 122.7 14.4 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 EGB07734.1 - 0.0001 22.0 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Herpes_UL25 PF01499.16 EGB07735.1 - 0.62 8.5 3.9 1.5 7.2 3.9 1.5 1 0 0 1 1 1 0 Herpesvirus UL25 family Phage_tail_S PF05069.13 EGB07735.1 - 8.2 6.3 12.0 6.3 6.6 1.6 3.2 3 0 0 3 3 3 0 Phage virion morphogenesis family WASH-7_mid PF14744.6 EGB07736.1 - 7.3e-131 436.4 0.0 1e-130 435.9 0.0 1.2 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_N PF14745.6 EGB07736.1 - 3.1e-76 257.1 0.0 4.3e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 EGB07736.1 - 1.8e-60 203.6 0.1 2.8e-60 203.0 0.1 1.3 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal DnaJ PF00226.31 EGB07737.1 - 4.4e-23 81.2 0.2 4.9e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 DnaJ domain OSCP PF00213.18 EGB07738.1 - 2e-43 148.5 5.1 2.2e-43 148.3 5.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF3306 PF11748.8 EGB07738.1 - 0.38 11.6 2.6 0.26 12.2 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Aminotran_1_2 PF00155.21 EGB07739.1 - 2.4e-82 277.0 0.0 2.7e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Hexapep PF00132.24 EGB07740.1 - 9.6e-14 50.5 11.9 5.3e-09 35.5 1.8 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB07740.1 - 1.1e-05 25.0 16.2 0.00051 19.7 4.5 2.7 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 EGB07740.1 - 0.0001 22.6 0.1 0.00018 21.8 0.1 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal TPR_2 PF07719.17 EGB07741.1 - 0.042 14.0 0.0 0.2 11.9 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 EGB07743.1 - 3.4e-51 174.2 3.1 4.1e-51 174.0 3.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB07743.1 - 2.4e-29 101.8 0.3 1.6e-28 99.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB07743.1 - 3.2e-14 53.2 3.5 5.3e-11 42.9 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB07743.1 - 2.8e-06 26.8 0.1 0.03 13.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGB07743.1 - 3e-05 23.4 0.6 5.8e-05 22.4 0.6 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGB07743.1 - 3.3e-05 23.2 7.8 0.00014 21.1 7.8 2.3 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGB07743.1 - 6.2e-05 21.9 2.5 0.00099 17.9 0.4 2.8 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EGB07743.1 - 0.00031 20.2 0.3 0.00044 19.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EGB07743.1 - 0.00089 18.4 0.4 0.00089 18.4 0.4 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGB07743.1 - 0.0041 17.3 0.2 0.012 15.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB07743.1 - 0.0078 15.8 8.0 0.16 11.5 7.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EGB07743.1 - 0.0084 15.4 2.2 0.028 13.7 0.1 2.3 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EGB07743.1 - 0.22 10.5 0.5 0.43 9.6 0.5 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DENN PF02141.21 EGB07745.1 - 1.3e-17 64.4 0.0 3e-14 53.4 0.1 2.2 2 0 0 2 2 2 2 DENN (AEX-3) domain IFT81_CH PF18383.1 EGB07745.1 - 0.0022 18.3 0.0 0.0048 17.2 0.0 1.5 1 1 0 1 1 1 1 Intraflagellar transport 81 calponin homology domain uDENN PF03456.18 EGB07745.1 - 0.0063 17.2 0.2 0.031 15.0 0.0 2.1 2 0 0 2 2 2 1 uDENN domain Peptidase_S41 PF03572.18 EGB07746.1 - 1.3e-40 138.6 0.0 1.8e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EGB07746.1 - 5e-07 29.5 0.2 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EGB07746.1 - 0.00021 21.6 0.1 0.00042 20.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGB07746.1 - 0.015 15.6 0.4 0.035 14.4 0.1 1.8 2 0 0 2 2 2 0 PDZ domain Pkinase PF00069.25 EGB07747.1 - 7.1e-30 104.2 0.0 8.2e-17 61.4 0.1 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07747.1 - 8.2e-21 74.4 0.0 1.9e-13 50.3 0.1 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGB07747.1 - 0.0081 15.5 0.1 2.7 7.3 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Atg14 PF10186.9 EGB07747.1 - 0.43 9.6 7.4 0.19 10.8 0.1 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tho2 PF11262.8 EGB07747.1 - 4.6 6.3 4.6 13 4.8 0.2 2.4 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 KH_8 PF17903.1 EGB07749.1 - 0.00065 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGB07749.1 - 0.0015 18.3 0.2 0.0032 17.2 0.2 1.5 1 0 0 1 1 1 1 KH domain HIT PF01230.23 EGB07749.1 - 0.14 13.0 0.0 0.19 12.5 0.0 1.3 1 0 0 1 1 1 0 HIT domain LRR_8 PF13855.6 EGB07751.1 - 2e-09 37.1 1.5 6.9e-09 35.3 0.2 2.5 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EGB07751.1 - 0.00027 21.2 5.3 0.0013 19.1 0.4 3.5 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB07751.1 - 0.00028 21.0 0.2 2 9.3 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 EGB07751.1 - 0.011 15.7 4.1 18 5.7 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat ANAPC1 PF12859.7 EGB07751.1 - 1.2 9.7 8.5 0.086 13.4 2.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 PRIMA1 PF16101.5 EGB07751.1 - 2.7 8.0 7.4 9 6.4 7.4 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RF-1 PF00472.20 EGB07752.1 - 3.9e-19 68.7 0.2 6.1e-19 68.1 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain Vps5 PF09325.10 EGB07754.1 - 5.9e-37 127.5 2.2 9.3e-37 126.8 2.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGB07754.1 - 5.7e-27 93.9 0.2 1.3e-26 92.8 0.1 1.7 2 0 0 2 2 2 1 PX domain BAR PF03114.18 EGB07754.1 - 9.2e-07 28.7 3.8 1.7e-06 27.9 3.8 1.4 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.9 EGB07754.1 - 2.6e-06 27.1 4.6 0.00013 21.5 3.3 2.6 1 1 1 2 2 2 1 WASP-binding domain of Sorting nexin protein BAR_3 PF16746.5 EGB07754.1 - 0.00092 19.0 1.0 0.0073 16.0 1.0 2.1 1 1 0 1 1 1 1 BAR domain of APPL family DUF1084 PF06454.11 EGB07755.1 - 6.3e-38 130.7 12.0 7.3e-38 130.5 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF3624 PF12292.8 EGB07755.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3624) IpgD PF05925.12 EGB07756.1 - 0.021 13.4 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Y_phosphatase3 PF13350.6 EGB07756.1 - 0.041 13.9 0.1 0.041 13.9 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Trp_Tyr_perm PF03222.13 EGB07757.1 - 2.4e-24 86.1 0.1 4.4e-24 85.3 0.1 1.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Pkinase PF00069.25 EGB07758.1 - 3.4e-63 213.5 0.0 4.2e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07758.1 - 9.1e-27 94.0 0.0 1.2e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGB07758.1 - 3.4e-06 27.4 0.0 7.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Pkinase_fungal PF17667.1 EGB07758.1 - 1.6e-05 23.9 0.0 0.00011 21.1 0.0 2.0 1 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGB07758.1 - 3.2e-05 24.0 5.4 9.2e-05 22.5 0.0 3.0 2 2 2 4 4 4 1 Phosphotransferase enzyme family EF-hand_1 PF00036.32 EGB07758.1 - 0.00035 19.9 0.1 0.0079 15.7 0.0 2.8 3 0 0 3 3 3 1 EF hand Kdo PF06293.14 EGB07758.1 - 0.00049 19.5 0.1 0.0021 17.4 0.1 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB07758.1 - 0.00054 19.4 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like EF-hand_6 PF13405.6 EGB07758.1 - 0.0027 17.5 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 EGB07758.1 - 0.012 15.8 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_5 PF13202.6 EGB07758.1 - 0.043 13.3 0.1 0.098 12.2 0.1 1.6 1 0 0 1 1 1 0 EF hand Vps52 PF04129.12 EGB07759.1 - 2.9e-93 313.4 0.0 7.2e-93 312.0 0.0 1.6 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.9 EGB07759.1 - 5.5e-09 35.0 0.0 7.6e-07 27.9 0.0 2.4 2 0 0 2 2 2 2 Exocyst complex component Sec3 T_hemolysin PF12261.8 EGB07759.1 - 0.1 12.4 1.3 15 5.3 0.0 3.3 3 0 0 3 3 3 0 Thermostable hemolysin Asp-B-Hydro_N PF05279.11 EGB07760.1 - 1.2 9.1 19.3 1.8 8.6 19.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SNF2_N PF00176.23 EGB07762.1 - 1.1e-62 211.8 0.0 1.6e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB07762.1 - 4.4e-18 65.7 0.0 8.8e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB07762.1 - 4e-07 30.2 0.0 6.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB07762.1 - 5e-05 23.1 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EGB07762.1 - 0.00031 20.0 0.0 0.0024 17.1 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PUMA PF15826.5 EGB07762.1 - 0.089 13.0 0.0 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis zf-CHC2 PF01807.20 EGB07763.1 - 3.4e-18 65.3 0.0 3.6e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 CHC2 zinc finger AAA_2 PF07724.14 EGB07764.1 - 2.2e-29 102.8 0.0 4.1e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGB07764.1 - 7.2e-14 52.3 0.0 1.6e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGB07764.1 - 6.6e-07 29.3 0.1 2.9e-06 27.2 0.1 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 EGB07764.1 - 1.1e-05 24.6 0.1 0.00013 21.2 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 EGB07764.1 - 2.9e-05 24.5 0.0 6.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EGB07764.1 - 4.2e-05 23.0 0.1 0.017 14.5 0.1 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGB07764.1 - 8e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGB07764.1 - 0.00012 22.1 0.1 0.00035 20.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB07764.1 - 0.00012 22.3 0.5 0.00054 20.3 0.1 2.2 2 1 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 EGB07764.1 - 0.00015 21.5 0.0 0.002 17.8 0.0 2.5 2 1 0 2 2 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGB07764.1 - 0.00053 19.9 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EGB07764.1 - 0.0014 19.0 1.6 1.1 9.7 0.1 3.5 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 EGB07764.1 - 0.0026 18.3 0.0 0.0058 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB07764.1 - 0.0045 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB07764.1 - 0.0054 17.1 0.1 0.088 13.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EGB07764.1 - 0.011 15.8 0.0 0.026 14.7 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGB07764.1 - 0.017 14.8 0.0 0.056 13.2 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 EGB07764.1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB07764.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGB07764.1 - 0.026 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 EGB07764.1 - 0.03 14.1 0.0 0.069 12.9 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 EGB07764.1 - 0.031 13.4 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EGB07764.1 - 0.042 14.1 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EGB07764.1 - 0.043 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 EGB07764.1 - 0.059 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EGB07764.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGB07764.1 - 0.063 13.0 0.2 0.15 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 EGB07764.1 - 0.071 12.5 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein SKI PF01202.22 EGB07764.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase NACHT PF05729.12 EGB07764.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 EGB07764.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_21 PF13304.6 EGB07764.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TIP49 PF06068.13 EGB07764.1 - 0.12 11.6 0.1 0.25 10.5 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 EGB07764.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGB07764.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 EGB07764.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.10 EGB07764.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.6 2 0 0 2 2 1 0 Signal recognition particle receptor beta subunit DLIC PF05783.11 EGB07764.1 - 0.19 10.5 0.0 0.37 9.5 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RNA_helicase PF00910.22 EGB07764.1 - 0.2 12.0 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DOPA_dioxygen PF08883.11 EGB07766.1 - 1.1e-09 38.4 0.0 5.5e-05 23.3 0.0 4.4 4 1 0 4 4 4 2 Dopa 4,5-dioxygenase family AAA_12 PF13087.6 EGB07767.1 - 2e-25 89.6 0.7 2.1e-25 89.5 0.7 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB07767.1 - 9.1e-05 22.2 0.3 0.00013 21.7 0.3 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ATP-synt PF00231.19 EGB07768.1 - 1.1e-71 241.8 0.9 1.3e-71 241.6 0.9 1.0 1 0 0 1 1 1 1 ATP synthase Ribonuc_L-PSP PF01042.21 EGB07769.1 - 1e-22 80.4 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.17 EGB07769.1 - 0.056 13.8 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 BON domain SIR2 PF02146.17 EGB07770.1 - 1.8e-44 151.8 0.0 2.2e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family ABC_tran PF00005.27 EGB07771.1 - 2.8e-06 27.9 0.0 3.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Peptidase_C1 PF00112.23 EGB07772.1 - 8.3e-49 166.6 3.3 1e-48 166.3 3.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB07772.1 - 2.9e-05 23.0 0.3 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Nop PF01798.18 EGB07773.1 - 6.5e-83 277.7 0.1 6.4e-82 274.5 0.1 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGB07773.1 - 2.1e-18 66.4 0.8 7.5e-18 64.7 0.8 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain YqcI_YcgG PF08892.11 EGB07773.1 - 0.0062 16.4 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 YqcI/YcgG family RNA_polI_A34 PF08208.11 EGB07773.1 - 0.016 15.3 23.3 0.03 14.4 23.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ank_2 PF12796.7 EGB07774.1 - 1.4e-15 57.6 0.4 1.7e-15 57.4 0.4 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB07774.1 - 3e-14 51.7 0.9 0.0005 20.3 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EGB07774.1 - 2.4e-13 50.3 0.1 8.7e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB07774.1 - 3.7e-11 43.1 0.4 2.3e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB07774.1 - 2.6e-10 40.3 2.7 0.014 15.8 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat zf-RanBP PF00641.18 EGB07775.1 - 0.023 14.0 1.9 0.046 13.0 1.9 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Glycos_transf_2 PF00535.26 EGB07776.1 - 1.2e-07 31.7 0.0 2.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB07776.1 - 0.066 13.1 0.2 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 GRIM-19 PF06212.12 EGB07777.1 - 3.9e-31 107.7 0.1 4.7e-31 107.5 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein 2OG-FeII_Oxy_3 PF13640.6 EGB07778.1 - 5e-11 43.3 0.0 5.7e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB07778.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Tubulin PF00091.25 EGB07780.1 - 3.6e-63 213.3 0.0 5e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB07780.1 - 2.4e-49 166.7 0.0 3.5e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Anoctamin PF04547.12 EGB07781.1 - 8.6e-104 347.9 12.0 7.2e-76 255.8 0.4 2.0 1 1 1 2 2 2 2 Calcium-activated chloride channel Metallophos PF00149.28 EGB07782.1 - 6.4e-16 59.5 0.2 1.1e-15 58.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhyH PF05721.13 EGB07782.1 - 8.7e-09 35.9 0.0 1.9e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Metallophos_C PF14008.6 EGB07782.1 - 0.00075 20.3 0.0 0.0021 18.9 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGB07782.1 - 0.055 14.0 0.0 0.37 11.4 0.0 2.2 1 1 1 2 2 2 0 Purple acid Phosphatase, N-terminal domain Sulfotransfer_2 PF03567.14 EGB07783.1 - 0.049 13.5 0.3 0.99 9.3 0.1 2.5 2 1 0 2 2 2 0 Sulfotransferase family eIF-1a PF01176.19 EGB07784.1 - 8.8e-23 79.9 0.3 1.2e-22 79.4 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HisG PF01634.18 EGB07785.1 - 1.9e-54 184.0 0.0 2.5e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EGB07785.1 - 4.1e-25 87.7 0.2 9.8e-25 86.5 0.2 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain LysR_substrate PF03466.20 EGB07785.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain TTL PF03133.15 EGB07786.1 - 1.4e-63 214.8 0.0 3.2e-44 151.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family FH2 PF02181.23 EGB07786.1 - 2.3e-27 96.1 0.0 1.2e-26 93.7 0.0 2.0 1 1 0 1 1 1 1 Formin Homology 2 Domain FAD_binding_3 PF01494.19 EGB07786.1 - 8.3e-06 25.3 0.3 7.4e-05 22.2 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain ATPgrasp_YheCD PF14398.6 EGB07786.1 - 6.2e-05 22.4 0.1 0.0077 15.5 0.0 2.8 2 1 1 3 3 3 1 YheC/D like ATP-grasp CCDC53 PF10152.9 EGB07786.1 - 0.0021 18.5 0.1 0.0021 18.5 0.1 6.6 3 3 1 4 4 4 2 Subunit CCDC53 of WASH complex ATPgrasp_ST PF14397.6 EGB07786.1 - 0.058 12.6 0.0 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF829 PF05705.14 EGB07790.1 - 5.6e-11 42.8 0.0 4.7e-09 36.5 0.0 3.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Cu_bind_like PF02298.17 EGB07791.1 - 2.9e-05 24.0 0.3 0.17 11.9 0.1 2.3 2 0 0 2 2 2 2 Plastocyanin-like domain Peptidase_C2 PF00648.21 EGB07792.1 - 2.6e-27 95.6 0.0 3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease tRNA-synt_2 PF00152.20 EGB07794.1 - 2e-80 270.2 0.0 2.4e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGB07794.1 - 4.2e-15 55.5 0.1 7.2e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGB07794.1 - 3.4e-06 26.7 0.0 0.04 13.4 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) DEAD PF00270.29 EGB07795.1 - 9.1e-07 28.8 0.0 1.4e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB07795.1 - 2.5e-06 27.8 0.0 6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Spc7 PF08317.11 EGB07795.1 - 1.6 7.5 5.4 3.3 6.5 5.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Herpes_UL25 PF01499.16 EGB07795.1 - 2.4 6.6 4.4 4.2 5.8 4.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family LETM1 PF07766.13 EGB07796.1 - 3.4e-93 311.9 0.0 3.8e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 EGB07796.1 - 0.031 14.0 0.9 0.063 13.0 0.1 2.0 2 0 0 2 2 2 0 SAP domain ECH_1 PF00378.20 EGB07797.1 - 1.5e-77 260.4 0.8 1.7e-77 260.2 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB07797.1 - 2.2e-31 109.6 3.7 1e-30 107.4 1.4 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MreB_Mbl PF06723.13 EGB07797.1 - 0.035 12.9 0.2 0.061 12.1 0.2 1.3 1 0 0 1 1 1 0 MreB/Mbl protein IQ PF00612.27 EGB07798.1 - 1.8e-05 24.1 37.1 0.12 12.2 1.3 8.5 8 0 0 8 8 8 6 IQ calmodulin-binding motif TnpV PF14198.6 EGB07798.1 - 0.15 12.0 1.2 0.38 10.8 1.2 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpV 2OG-FeII_Oxy_3 PF13640.6 EGB07799.1 - 1.9e-05 25.5 0.0 4.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF99 PF01949.16 EGB07799.1 - 0.16 11.4 0.1 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF99 DHHC PF01529.20 EGB07800.1 - 2.4e-28 98.9 5.9 2.4e-28 98.9 5.9 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3487 PF11990.8 EGB07800.1 - 0.086 12.7 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Ank_2 PF12796.7 EGB07801.1 - 1.1e-08 35.6 0.1 0.00013 22.4 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB07801.1 - 1.2e-05 25.5 0.6 5.7e-05 23.3 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB07801.1 - 0.00017 21.9 0.6 0.0098 16.3 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGB07801.1 - 0.00042 20.8 0.2 0.045 14.3 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB07801.1 - 0.08 13.5 0.7 0.54 11.0 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat PKD_channel PF08016.12 EGB07802.1 - 3.4e-27 95.2 16.3 3.8e-19 68.7 3.5 3.0 3 0 0 3 3 3 2 Polycystin cation channel Glyco_trans_1_4 PF13692.6 EGB07802.1 - 7.2e-17 62.1 0.1 2.9e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Ion_trans PF00520.31 EGB07802.1 - 1.1e-15 57.5 14.3 1.9e-15 56.8 14.3 1.3 1 0 0 1 1 1 1 Ion transport protein HATPase_c PF02518.26 EGB07802.1 - 5.4e-08 33.3 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glycos_transf_1 PF00534.20 EGB07802.1 - 0.00021 20.9 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGB07802.1 - 0.00055 20.3 0.8 0.003 17.9 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 EF-hand_5 PF13202.6 EGB07802.1 - 0.002 17.6 0.1 0.0055 16.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EGB07802.1 - 0.0059 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 EF hand Med26 PF08711.11 EGB07802.1 - 0.015 15.3 0.3 0.027 14.5 0.3 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain HATPase_c_3 PF13589.6 EGB07802.1 - 0.023 14.6 0.1 0.071 12.9 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CSN8_PSD8_EIF3K PF10075.9 EGB07803.1 - 1.1e-10 41.6 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Lamprin PF06403.11 EGB07803.1 - 6.2e-05 23.0 21.7 0.15 12.1 0.4 5.6 1 1 3 4 4 4 3 Lamprin Chorion_1 PF01723.16 EGB07803.1 - 0.1 12.6 11.5 26 4.7 0.2 5.4 1 1 4 5 5 5 0 Chorion protein Sep15_SelM PF08806.11 EGB07804.1 - 2.8e-22 78.7 0.0 3.7e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Sep15/SelM redox domain HAUS4 PF14735.6 EGB07804.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 PolyA_pol PF01743.20 EGB07805.1 - 1e-26 93.9 0.1 1.3e-26 93.5 0.1 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain Aminoglyc_resit PF10706.9 EGB07805.1 - 0.06 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase DUF1833 PF08875.11 EGB07805.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) ADH_zinc_N_2 PF13602.6 EGB07805.1 - 0.1 13.7 0.1 0.24 12.5 0.1 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase zf-MYND PF01753.18 EGB07806.1 - 5.9e-10 39.1 19.7 5.9e-10 39.1 19.7 4.0 2 2 1 3 3 3 2 MYND finger zf-C6H2 PF15801.5 EGB07806.1 - 0.27 11.6 15.5 0.088 13.1 11.5 2.2 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 EGB07806.1 - 3 8.0 11.6 12 6.1 8.5 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 RSN1_7TM PF02714.15 EGB07807.1 - 1.9e-06 27.4 3.0 1.9e-06 27.4 3.0 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGB07807.1 - 0.0019 18.5 2.7 3 8.1 0.0 4.0 4 0 0 4 4 4 3 Cytosolic domain of 10TM putative phosphate transporter Myosin_head PF00063.21 EGB07808.1 - 2.1e-204 680.6 0.0 2.5e-204 680.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB07808.1 - 0.00039 20.8 0.1 0.0012 19.3 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGB07808.1 - 0.0059 16.9 0.2 0.03 14.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.12 EGB07808.1 - 0.011 15.2 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 EGB07808.1 - 0.042 14.2 0.1 2.9 8.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 EGB07808.1 - 0.061 12.6 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 EGB07808.1 - 0.12 11.2 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.26 EGB07808.1 - 0.19 11.4 1.0 0.39 10.4 0.1 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain CS PF04969.16 EGB07809.1 - 3.8e-11 43.8 0.0 5.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 CS domain SET PF00856.28 EGB07810.1 - 9.1e-05 22.9 0.0 0.00028 21.3 0.0 1.7 2 0 0 2 2 2 1 SET domain GST_N_3 PF13417.6 EGB07811.1 - 3.2e-12 46.7 0.0 8.3e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB07811.1 - 9.6e-11 41.8 0.4 1.8e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB07811.1 - 6.1e-07 29.4 3.1 1.6e-06 28.0 3.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB07811.1 - 5.3e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ABC2_membrane PF01061.24 EGB07812.1 - 6.5e-23 81.3 9.7 9.3e-23 80.7 9.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGB07812.1 - 1.2e-20 74.5 0.0 1.6e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB07812.1 - 0.00034 20.5 1.9 0.22 11.3 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGB07812.1 - 0.00056 19.1 8.3 0.00076 18.7 8.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGB07812.1 - 0.062 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EGB07812.1 - 0.094 12.3 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGB07812.1 - 0.15 11.8 0.2 0.39 10.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain 2OG-FeII_Oxy_3 PF13640.6 EGB07813.1 - 3e-09 37.6 0.0 5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sel1 PF08238.12 EGB07814.1 - 9.4e-41 137.3 38.7 5.6e-08 33.2 0.3 8.3 8 1 0 8 8 8 7 Sel1 repeat TPR_3 PF07720.12 EGB07814.1 - 0.0043 17.0 4.1 0.05 13.6 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB07814.1 - 0.017 14.9 0.7 0.017 14.9 0.7 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat PSD5 PF07637.11 EGB07814.1 - 0.093 13.1 4.5 17 5.8 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1595) DUF410 PF04190.13 EGB07814.1 - 0.39 10.5 2.1 2.4 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF410) B12-binding_2 PF02607.17 EGB07814.1 - 0.45 11.0 4.7 22 5.6 0.4 3.7 2 2 2 4 4 4 0 B12 binding domain FumaraseC_C PF10415.9 EGB07814.1 - 0.96 9.9 4.2 18 5.9 0.1 3.8 4 0 0 4 4 4 0 Fumarase C C-terminus TPR_12 PF13424.6 EGB07814.1 - 3.4 8.0 25.3 0.82 10.0 3.3 5.7 3 1 3 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB07814.1 - 7 6.7 24.2 0.51 10.3 1.9 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat U-box PF04564.15 EGB07815.1 - 6e-23 80.8 0.0 6.5e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB07815.1 - 1.6e-05 24.6 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGB07815.1 - 3.7e-05 23.7 0.0 5.9e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EGB07815.1 - 0.00061 19.9 0.0 0.00081 19.5 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-rbx1 PF12678.7 EGB07815.1 - 0.11 12.8 0.0 0.51 10.7 0.0 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGB07815.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING EF-hand_1 PF00036.32 EGB07817.1 - 1.9e-11 42.6 0.4 1.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB07817.1 - 2.2e-10 39.6 0.4 1.4e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB07817.1 - 2.6e-09 36.1 0.4 2.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB07817.1 - 5.7e-09 36.3 0.1 6.3e-09 36.2 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB07817.1 - 1.1e-06 28.4 1.2 0.00098 18.9 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair Mito_carr PF00153.27 EGB07818.1 - 8.9e-23 80.0 1.1 2.7e-16 59.2 0.3 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Fe_hyd_lg_C PF02906.14 EGB07818.1 - 0.093 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain SET PF00856.28 EGB07819.1 - 1.2e-19 71.4 0.0 4.7e-19 69.4 0.0 1.8 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EGB07819.1 - 1.9e-06 27.8 3.3 1.9e-06 27.8 3.3 2.3 3 0 0 3 3 3 1 AWS domain Bac_rhamnosid_C PF17390.2 EGB07820.1 - 8.7e-06 25.4 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 EGB07820.1 - 0.00047 19.5 5.6 0.0076 15.5 5.6 2.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Gal_Lectin PF02140.18 EGB07820.1 - 0.0019 18.6 0.9 0.0041 17.5 0.9 1.5 1 0 0 1 1 1 1 Galactose binding lectin domain Bac_rhamnosid PF05592.11 EGB07820.1 - 0.0046 16.9 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain RRM_1 PF00076.22 EGB07821.1 - 2e-23 82.0 0.0 1.5e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB07821.1 - 0.00096 19.2 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif Rrn6 PF10214.9 EGB07821.1 - 0.52 8.7 2.3 0.7 8.3 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ribosomal_S2 PF00318.20 EGB07823.1 - 2.2e-28 99.0 0.1 1e-13 51.0 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EGB07823.1 - 0.0075 17.6 3.0 0.016 16.6 3.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Poxvirus PF06227.12 EGB07823.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus DUF3493 PF11998.8 EGB07824.1 - 6.2e-19 67.9 0.3 1.6e-18 66.6 0.1 1.9 2 0 0 2 2 2 1 Low psii accumulation1 / Rep27 C2 PF00168.30 EGB07824.1 - 2.4e-17 63.1 0.0 4.2e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain FeThRed_B PF02943.15 EGB07825.1 - 3.8e-40 136.2 1.0 4.5e-40 135.9 1.0 1.1 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain Lactamase_B PF00753.27 EGB07826.1 - 2.3e-15 57.1 0.7 8.2e-13 48.8 0.6 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EGB07826.1 - 4.1e-10 39.5 0.1 1.2e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EGB07826.1 - 1.4e-07 31.2 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGB07826.1 - 0.028 14.3 0.0 0.1 12.5 0.0 1.7 1 1 0 2 2 2 0 Beta-lactamase superfamily domain EcKinase PF02958.20 EGB07828.1 - 8.6e-13 48.3 0.0 2.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase Choline_kinase PF01633.20 EGB07828.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EGB07828.1 - 0.21 10.4 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) PEMT PF04191.13 EGB07829.1 - 6.3e-07 29.7 0.2 6.3e-07 29.7 0.2 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase PAN_1 PF00024.26 EGB07829.1 - 0.00023 21.1 0.1 0.00055 19.8 0.1 1.6 1 0 0 1 1 1 1 PAN domain DUF346 PF03984.13 EGB07829.1 - 0.31 10.8 2.7 0.42 10.4 0.2 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) PAN_4 PF14295.6 EGB07829.1 - 0.91 9.5 7.6 0.17 11.8 2.8 2.4 2 0 0 2 2 2 0 PAN domain Rieske_2 PF13806.6 EGB07832.1 - 2.3e-12 46.8 0.0 3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 EGB07832.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Chloroa_b-bind PF00504.21 EGB07833.1 - 1.9e-27 96.7 0.5 2.5e-27 96.4 0.5 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Sel1 PF08238.12 EGB07834.1 - 5.9e-52 172.9 31.1 9.6e-09 35.6 0.1 10.2 10 0 0 10 10 10 7 Sel1 repeat AAA_lid_10 PF17872.1 EGB07834.1 - 9.7e-05 22.4 0.5 4 7.6 0.0 3.4 3 0 0 3 3 3 2 AAA lid domain TPR_16 PF13432.6 EGB07834.1 - 0.0002 21.9 32.4 0.022 15.4 5.3 6.7 4 2 3 7 7 7 2 Tetratricopeptide repeat DUF977 PF06163.11 EGB07834.1 - 0.0016 18.4 2.2 2.6 8.0 0.0 4.4 2 2 3 6 6 6 1 Bacterial protein of unknown function (DUF977) PDDEXK_10 PF07788.11 EGB07834.1 - 0.0024 17.8 1.1 4.7 7.2 0.1 3.5 3 0 0 3 3 3 1 PD-(D/E)XK nuclease superfamily PhoD PF09423.10 EGB07834.1 - 0.0062 15.6 0.1 2.2 7.2 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase YicC_N PF03755.13 EGB07834.1 - 0.043 14.3 0.9 13 6.2 0.1 3.1 3 0 0 3 3 3 0 YicC-like family, N-terminal region NSF PF02071.20 EGB07834.1 - 1.4 10.0 4.3 3.7e+02 2.8 0.0 5.0 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_12 PF13424.6 EGB07834.1 - 9.3 6.6 27.2 0.41 11.0 0.4 6.8 5 3 2 7 7 7 0 Tetratricopeptide repeat Chloroa_b-bind PF00504.21 EGB07835.1 - 8.7e-26 91.4 0.0 1.2e-25 90.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein WD40 PF00400.32 EGB07836.1 - 3.4e-35 119.4 28.0 2e-07 31.6 0.8 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB07836.1 - 1e-13 51.4 0.2 0.35 11.2 0.0 5.3 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB07836.1 - 1.2e-07 31.0 1.4 0.19 10.7 0.1 3.4 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGB07836.1 - 0.004 15.9 0.4 0.2 10.3 0.0 2.5 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Sugar_tr PF00083.24 EGB07837.1 - 3.4e-77 260.2 10.2 4.4e-77 259.9 10.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB07837.1 - 3.5e-16 59.1 43.6 1.1e-11 44.3 15.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGB07837.1 - 0.00033 19.3 19.6 0.02 13.5 6.6 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein DUF563 PF04577.14 EGB07838.1 - 1.8e-11 44.6 0.0 3.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) SH2_2 PF14633.6 EGB07839.1 - 7.8e-41 139.8 0.0 1.2e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 EGB07839.1 - 5.4e-15 55.8 0.1 1.1e-14 54.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EGB07839.1 - 2.7e-10 40.5 0.0 3.5e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EGB07839.1 - 1.3e-06 28.3 0.0 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 S1 PF00575.23 EGB07839.1 - 0.0001 22.6 0.1 0.00022 21.5 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 EGB07839.1 - 0.00024 21.9 0.1 0.3 12.0 0.0 2.9 2 0 0 2 2 2 2 HHH domain SPT6_acidic PF14632.6 EGB07839.1 - 0.0013 19.3 14.4 0.0013 19.3 14.4 6.0 5 2 1 6 6 6 1 Acidic N-terminal SPT6 Glyco_transf_4 PF13439.6 EGB07839.1 - 0.027 14.5 0.0 0.084 12.9 0.0 1.9 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sel1 PF08238.12 EGB07840.1 - 2.5e-14 53.4 11.8 7.8e-06 26.4 0.2 4.5 4 0 0 4 4 4 3 Sel1 repeat zf-MYND PF01753.18 EGB07840.1 - 1.7e-08 34.4 10.9 3.3e-08 33.5 10.9 1.5 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.28 EGB07840.1 - 0.11 12.4 0.6 0.36 10.7 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-HIT PF04438.16 EGB07840.1 - 0.27 11.1 7.2 0.5 10.3 7.2 1.5 1 0 0 1 1 1 0 HIT zinc finger TPR_12 PF13424.6 EGB07840.1 - 1.7 9.0 5.3 1.2 9.5 0.4 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Gtr1_RagA PF04670.12 EGB07842.1 - 2.7e-48 164.3 0.0 3.3e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB07842.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB07842.1 - 0.041 13.3 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EGB07842.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase LCM PF04072.14 EGB07843.1 - 6.7e-23 81.6 0.1 1.1e-22 80.9 0.1 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Rieske PF00355.26 EGB07843.1 - 1.4e-15 57.0 0.0 2.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FA_hydroxylase PF04116.13 EGB07844.1 - 8.4e-18 65.0 12.3 2e-17 63.8 12.3 1.7 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily OmpA PF00691.20 EGB07844.1 - 0.065 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 OmpA family Importin_rep_4 PF18808.1 EGB07844.1 - 0.18 12.1 1.3 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Importin repeat Thioredoxin_4 PF13462.6 EGB07845.1 - 0.069 13.3 0.2 0.25 11.5 0.2 2.0 1 1 0 1 1 1 0 Thioredoxin KR PF08659.10 EGB07846.1 - 7.9e-36 123.6 0.0 1.2e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EGB07846.1 - 3e-06 27.0 0.0 5.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB07846.1 - 0.015 14.7 0.2 0.081 12.4 0.2 2.3 2 1 0 2 2 2 0 short chain dehydrogenase Prp18 PF02840.15 EGB07847.1 - 8.3e-52 175.0 0.6 1.1e-51 174.6 0.6 1.2 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 EGB07847.1 - 2.8e-10 39.5 0.2 5.6e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like GEN1_C PF18380.1 EGB07847.1 - 0.64 10.9 3.4 0.32 11.9 0.6 1.9 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Aldo_ket_red PF00248.21 EGB07848.1 - 1.1e-37 129.8 0.0 1.8e-36 125.9 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family CENP-B_dimeris PF09026.10 EGB07849.1 - 0.016 15.6 1.7 0.021 15.2 1.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ETF_QO PF05187.13 EGB07850.1 - 7.9e-31 106.3 0.0 1.3e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 EGB07850.1 - 9.7e-08 31.5 2.3 0.0013 17.9 3.5 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGB07850.1 - 2.7e-07 30.5 5.4 0.00016 21.4 1.3 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGB07850.1 - 2.9e-05 24.2 0.0 8.5e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGB07850.1 - 3e-05 23.4 0.1 6.5e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EGB07850.1 - 6e-05 22.4 0.0 9.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGB07850.1 - 0.0001 21.5 0.4 0.00021 20.5 0.3 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGB07850.1 - 0.00019 20.8 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGB07850.1 - 0.00026 21.5 0.7 0.3 11.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB07850.1 - 0.0005 18.9 0.2 0.0018 17.1 0.7 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 EGB07850.1 - 0.0007 19.6 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGB07850.1 - 0.0013 18.1 0.7 0.0018 17.6 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB07850.1 - 0.025 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_7 PF12838.7 EGB07850.1 - 0.049 14.2 2.5 0.11 13.1 2.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAD_oxidored PF12831.7 EGB07850.1 - 0.052 12.9 0.1 0.069 12.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AIRS PF00586.24 EGB07850.1 - 0.095 13.4 0.2 11 6.7 0.1 3.1 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain Trp_halogenase PF04820.14 EGB07850.1 - 0.21 10.4 2.2 0.74 8.6 1.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 EGB07850.1 - 0.25 10.4 0.9 0.35 9.9 0.9 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A ubiquitin PF00240.23 EGB07851.1 - 2.9e-69 228.8 5.4 2.7e-34 116.7 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EGB07851.1 - 1.1e-32 111.6 6.8 3.3e-16 58.9 0.8 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB07851.1 - 2.2e-13 50.5 1.1 2.9e-05 24.4 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB07851.1 - 2e-08 34.0 0.3 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB07851.1 - 5.9e-08 32.8 0.2 0.013 15.5 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGB07851.1 - 7.2e-08 32.7 0.5 0.013 15.9 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 EGB07851.1 - 2e-06 28.3 0.1 0.049 14.2 0.0 2.2 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGB07851.1 - 0.00023 21.2 6.8 9 6.4 0.0 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGB07851.1 - 0.00097 19.0 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 EGB07851.1 - 0.018 15.4 0.0 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Raf1_HTH PF18579.1 EGB07851.1 - 0.053 13.2 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain DUF1940 PF09155.10 EGB07851.1 - 0.058 13.5 0.3 9.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) TmoB PF06234.12 EGB07851.1 - 0.086 12.9 0.3 7.4 6.7 0.1 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) FERM_f0 PF16511.5 EGB07851.1 - 0.12 12.7 2.4 34 4.8 0.2 3.6 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM DUF3861 PF12977.7 EGB07851.1 - 0.13 12.5 0.1 21 5.4 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) DUF969 PF06149.12 EGB07851.1 - 0.21 11.0 0.0 7.5 5.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Epimerase PF01370.21 EGB07852.1 - 1.4e-40 139.3 0.0 1.9e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB07852.1 - 1.9e-26 93.2 0.0 4.4e-25 88.8 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGB07852.1 - 1.4e-07 30.8 0.0 2.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGB07852.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGB07852.1 - 0.0071 15.5 0.0 2.5 7.1 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AnfG_VnfG PF03139.15 EGB07852.1 - 0.045 13.9 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit GidB PF02527.15 EGB07852.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G ClpS PF02617.17 EGB07853.1 - 3.8e-15 55.4 0.1 4.3e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Thioredoxin PF00085.20 EGB07854.1 - 1.9e-25 88.8 0.0 3.4e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB07854.1 - 0.0031 18.0 0.2 0.0097 16.3 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGB07854.1 - 0.0054 16.1 0.0 0.0067 15.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGB07854.1 - 0.032 14.4 0.1 0.086 13.0 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like NOA36 PF06524.12 EGB07854.1 - 0.037 13.4 15.7 0.053 12.8 15.7 1.3 1 0 0 1 1 1 0 NOA36 protein Thioredoxin_8 PF13905.6 EGB07854.1 - 0.043 14.1 0.0 0.46 10.8 0.0 2.4 2 1 1 3 3 3 0 Thioredoxin-like TraF PF13728.6 EGB07854.1 - 0.053 13.3 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 F plasmid transfer operon protein Cwf_Cwc_15 PF04889.12 EGB07854.1 - 0.33 10.6 18.9 0.47 10.1 18.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 EGB07854.1 - 1.6 8.3 13.8 2 7.9 13.8 1.1 1 0 0 1 1 1 0 PPP4R2 FUSC PF04632.12 EGB07854.1 - 4 5.9 4.3 5.1 5.5 4.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MMR_HSR1 PF01926.23 EGB07855.1 - 6.1e-22 77.9 0.0 6.8e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB07855.1 - 4e-08 32.9 0.0 4.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGB07855.1 - 0.0015 18.6 0.0 0.03 14.4 0.0 2.0 1 1 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 EGB07855.1 - 0.025 14.8 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGB07855.1 - 0.049 13.1 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EGB07855.1 - 0.051 14.1 0.0 0.074 13.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EGB07855.1 - 0.065 13.8 0.0 0.071 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EGB07855.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF2813 PF11398.8 EGB07855.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Arf PF00025.21 EGB07856.1 - 2e-24 86.0 0.0 1.4e-23 83.3 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGB07856.1 - 6.1e-14 51.9 0.0 8.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB07856.1 - 2.9e-07 30.7 0.0 4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGB07856.1 - 2.4e-06 26.9 0.1 4.5e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.27 EGB07856.1 - 0.0035 16.9 0.0 0.0041 16.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB07856.1 - 0.004 16.6 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGB07856.1 - 0.044 13.3 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 EGB07856.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-C6H2 PF15801.5 EGB07857.1 - 2.3 8.6 10.6 0.24 11.7 5.5 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding AAA_16 PF13191.6 EGB07860.1 - 9.1e-07 29.4 3.1 0.004 17.6 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGB07860.1 - 3e-06 26.9 0.1 0.016 15.0 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 EGB07860.1 - 5.9e-06 26.8 0.3 0.34 11.4 0.0 3.5 2 1 1 3 3 3 1 ABC transporter AAA_33 PF13671.6 EGB07860.1 - 2.2e-05 24.7 0.4 0.028 14.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGB07860.1 - 0.00055 20.2 1.6 0.071 13.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EGB07860.1 - 0.00082 18.5 0.0 0.99 8.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 EGB07860.1 - 0.0023 17.6 3.0 0.82 9.2 0.0 3.5 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 EGB07860.1 - 0.0028 17.4 5.0 0.17 11.6 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_21 PF13304.6 EGB07860.1 - 0.0044 16.9 0.6 2.1 8.1 0.2 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB07860.1 - 0.006 16.5 0.2 0.94 9.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EGB07860.1 - 0.015 15.8 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Acetyltransf_7 PF13508.7 EGB07860.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATPase_2 PF01637.18 EGB07860.1 - 0.03 14.2 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGB07860.1 - 0.1 12.3 1.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGB07860.1 - 0.11 12.6 0.3 25 5.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EGB07860.1 - 0.13 11.6 0.1 12 5.1 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 EGB07860.1 - 0.16 11.9 0.0 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Acetyltransf_1 PF00583.25 EGB07860.1 - 0.16 12.2 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGB07860.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GHL6 PF14871.6 EGB07860.1 - 0.18 11.9 0.0 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 ABC_ATPase PF09818.9 EGB07860.1 - 0.23 10.2 0.9 5.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 EGB07860.1 - 0.24 11.3 1.4 15 5.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EGB07860.1 - 0.46 10.7 4.0 2.9 8.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB07860.1 - 0.57 10.7 2.6 10 6.7 0.8 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGB07860.1 - 0.8 9.3 3.4 15 5.1 0.9 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EGB07860.1 - 1.7 8.4 4.0 33 4.1 2.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TMEM65 PF10507.9 EGB07861.1 - 5.1e-39 132.6 1.9 1.2e-38 131.4 1.9 1.6 1 0 0 1 1 1 1 Transmembrane protein 65 cNMP_binding PF00027.29 EGB07861.1 - 2.2e-06 27.7 0.0 7.8e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain TerB PF05099.13 EGB07861.1 - 0.0007 19.6 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TerB DUF4244 PF14029.6 EGB07861.1 - 0.39 10.2 1.9 14 5.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4244) Glyco_hydro_18 PF00704.28 EGB07863.1 - 1.1e-19 71.4 0.1 1.6e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SnoaL PF07366.12 EGB07863.1 - 0.15 11.8 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase 2OG-FeII_Oxy PF03171.20 EGB07864.1 - 1e-16 61.2 0.0 1.9e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGB07864.1 - 9e-15 55.5 0.0 1.3e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Aldo_ket_red PF00248.21 EGB07865.1 - 3.9e-27 95.2 0.0 8.7e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family IMS PF00817.20 EGB07866.1 - 1.8e-34 118.9 0.1 2.3e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 EGB07866.1 - 0.018 15.4 0.1 0.086 13.2 0.1 2.0 2 0 0 2 2 2 0 IMS family HHH motif Metallophos PF00149.28 EGB07869.1 - 3.1e-10 40.9 0.0 4e-09 37.3 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase TIM PF00121.18 EGB07870.1 - 1.1e-65 221.4 0.0 3.1e-65 219.9 0.0 1.6 1 1 0 1 1 1 1 Triosephosphate isomerase SBF_like PF13593.6 EGB07871.1 - 5.5e-48 163.9 16.8 7.7e-48 163.4 16.8 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Glyco_hydro_3_C PF01915.22 EGB07871.1 - 2.7e-36 125.5 0.0 1.9e-35 122.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGB07871.1 - 2.3e-28 99.5 0.0 4.7e-22 78.8 0.0 3.1 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGB07871.1 - 2.4e-08 34.0 0.0 5.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SBF PF01758.16 EGB07871.1 - 0.00026 20.7 2.5 0.0005 19.8 2.5 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family Cpn10 PF00166.21 EGB07872.1 - 1e-22 80.0 0.0 1.2e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF2512 PF10710.9 EGB07872.1 - 0.26 11.0 0.0 0.35 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) Endonuclease_5 PF04493.14 EGB07873.1 - 3.8e-48 163.8 0.0 1.7e-47 161.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 EGB07873.1 - 0.049 13.0 0.1 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF99 Elf1 PF05129.13 EGB07874.1 - 4.2e-29 100.4 2.4 4.7e-29 100.3 2.4 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 EGB07874.1 - 0.0019 18.6 1.5 0.0026 18.1 1.5 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar Vps36-NZF-N PF16988.5 EGB07874.1 - 0.0053 16.1 0.3 0.0072 15.7 0.3 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-H2C2_2 PF13465.6 EGB07874.1 - 0.013 15.9 1.8 0.45 11.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Anti-TRAP PF15777.5 EGB07874.1 - 0.018 15.0 1.1 0.025 14.6 1.1 1.2 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Trm112p PF03966.16 EGB07874.1 - 0.036 14.6 1.0 0.085 13.4 1.0 1.6 1 1 0 1 1 1 0 Trm112p-like protein HypA PF01155.19 EGB07874.1 - 0.083 12.9 2.6 0.38 10.8 2.1 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 EGB07874.1 - 0.096 13.6 3.3 6.4 7.9 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EGB07874.1 - 0.099 12.8 4.0 0.19 11.9 4.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-Mss51 PF13824.6 EGB07874.1 - 0.1 12.7 1.7 0.16 12.1 1.7 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-Sec23_Sec24 PF04810.15 EGB07874.1 - 0.12 12.4 3.4 1.2 9.3 1.1 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Cys_rich_CPXG PF14255.6 EGB07874.1 - 0.13 12.2 4.3 0.078 12.9 2.8 1.6 1 1 0 1 1 1 0 Cysteine-rich CPXCG zf-Di19 PF05605.12 EGB07874.1 - 0.37 11.1 4.9 2 8.8 4.9 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 EGB07874.1 - 0.67 10.0 3.3 3.3 7.8 3.3 2.1 1 1 0 1 1 1 0 BED zinc finger DnaJ PF00226.31 EGB07875.1 - 1.2e-21 76.5 0.3 2.3e-21 75.7 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Reprolysin PF01421.19 EGB07876.1 - 1.3e-13 51.3 0.0 6.3e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.23 EGB07876.1 - 2.4e-11 44.2 21.7 2.4e-11 44.2 21.7 4.0 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 EGB07876.1 - 7.1e-10 39.5 0.6 1.8e-09 38.2 0.6 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EGB07876.1 - 1e-09 38.6 0.4 1e-09 38.6 0.4 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EGB07876.1 - 1.2e-09 38.6 0.2 1.2e-09 38.6 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EGB07876.1 - 1.7e-07 31.1 1.3 3.7e-07 30.0 0.9 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 EGB07876.1 - 0.00037 21.0 2.7 0.00037 21.0 2.7 3.1 1 1 1 2 2 2 1 ADAM cysteine-rich domain Peptidase_M66 PF10462.9 EGB07876.1 - 0.014 14.4 1.7 0.022 13.8 1.7 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 EGB07876.1 - 0.085 12.4 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase MMR_HSR1 PF01926.23 EGB07877.1 - 1.1e-11 44.9 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB07877.1 - 0.00023 20.8 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB07877.1 - 0.0055 16.6 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGB07877.1 - 0.12 12.4 0.0 0.54 10.3 0.1 1.8 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 EGB07877.1 - 0.14 11.7 0.0 1.8 8.1 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B Sulfatase PF00884.23 EGB07878.1 - 1.8e-123 411.9 0.0 1.6e-66 224.8 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.22 EGB07878.1 - 5.2e-09 36.2 1.1 0.00031 20.4 0.1 3.3 3 1 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EGB07878.1 - 8e-05 23.4 0.0 0.019 15.7 0.0 2.6 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase zf-C3HC4_3 PF13920.6 EGB07878.1 - 0.0001 22.1 10.6 0.00029 20.6 10.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Arylsulfotrans PF05935.11 EGB07878.1 - 0.0029 16.6 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) ABC2_membrane PF01061.24 EGB07879.1 - 4e-39 134.2 0.9 5.9e-39 133.7 0.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGB07879.1 - 3.5e-21 76.2 0.0 5.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB07879.1 - 0.0012 19.3 0.1 0.0027 18.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB07879.1 - 0.0023 17.8 0.3 2.6 7.8 0.7 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB07879.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EGB07879.1 - 0.03 13.9 0.3 0.11 12.1 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGB07879.1 - 0.033 13.9 2.1 0.074 12.8 0.2 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB07879.1 - 0.087 13.3 0.5 0.14 12.6 0.5 1.2 1 0 0 1 1 1 0 AAA domain Chloroa_b-bind PF00504.21 EGB07880.1 - 3e-33 115.7 0.0 3.8e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Methyltransf_11 PF08241.12 EGB07882.1 - 6.1e-13 49.2 0.0 9.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB07882.1 - 4e-08 33.9 0.0 8.1e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB07882.1 - 8.7e-08 32.1 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB07882.1 - 9.2e-07 28.4 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGB07882.1 - 8.3e-06 26.5 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EGB07882.1 - 3.2e-05 22.7 0.0 5.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 EGB07882.1 - 6.1e-05 22.9 0.0 8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGB07882.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase DREV PF05219.12 EGB07882.1 - 0.014 14.5 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 EGB07882.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Adeno_PV PF03910.13 EGB07882.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV PALP PF00291.25 EGB07883.1 - 2.7e-61 207.6 0.0 3e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA PF00004.29 EGB07884.1 - 1.8e-44 151.4 0.0 4.3e-44 150.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGB07884.1 - 2.8e-08 33.6 0.3 1.5e-07 31.2 0.1 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EGB07884.1 - 1.2e-07 32.0 0.8 2.4e-07 31.0 0.0 1.9 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGB07884.1 - 1.5e-07 31.5 0.1 5.5e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB07884.1 - 9.9e-06 26.0 0.6 0.0074 16.7 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 EGB07884.1 - 3.4e-05 23.6 0.0 8.9e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGB07884.1 - 0.00011 22.0 0.0 0.00048 19.9 0.0 2.0 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB07884.1 - 0.00013 22.3 1.3 0.061 13.6 0.1 2.9 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.13 EGB07884.1 - 0.00036 19.8 0.2 0.0009 18.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EGB07884.1 - 0.00095 18.6 0.1 0.0023 17.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGB07884.1 - 0.0011 18.3 0.0 0.0023 17.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EGB07884.1 - 0.0016 18.0 0.2 0.0099 15.4 0.2 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGB07884.1 - 0.0021 18.6 0.0 0.007 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 EGB07884.1 - 0.005 17.2 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EGB07884.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGB07884.1 - 0.0073 16.5 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGB07884.1 - 0.0077 16.5 0.2 0.024 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGB07884.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGB07884.1 - 0.0094 15.7 0.2 0.16 11.7 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain DUF3450 PF11932.8 EGB07884.1 - 0.015 14.6 0.9 0.033 13.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NTPase_1 PF03266.15 EGB07884.1 - 0.019 14.9 0.0 0.075 12.9 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 EGB07884.1 - 0.021 14.6 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NUDE_C PF04880.13 EGB07884.1 - 0.023 15.2 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region AAA_14 PF13173.6 EGB07884.1 - 0.024 14.7 0.0 0.074 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGB07884.1 - 0.024 14.4 0.2 0.072 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB07884.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EGB07884.1 - 0.045 12.8 0.0 0.094 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TniB PF05621.11 EGB07884.1 - 0.058 12.8 0.0 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein IPT PF01745.16 EGB07884.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Isopentenyl transferase NACHT PF05729.12 EGB07884.1 - 0.082 12.8 0.1 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 EGB07884.1 - 0.083 12.7 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HIP1_clath_bdg PF16515.5 EGB07884.1 - 0.084 13.5 1.2 0.82 10.3 0.5 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATPase PF06745.13 EGB07884.1 - 0.11 11.8 1.5 0.38 10.1 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 EGB07884.1 - 0.27 10.8 1.2 0.79 9.3 0.2 2.0 1 1 1 2 2 2 0 AAA domain SNase PF00565.17 EGB07885.1 - 1.7e-06 28.4 0.1 7.3e-06 26.4 0.1 1.9 2 0 0 2 2 2 1 Staphylococcal nuclease homologue Excalibur PF05901.11 EGB07885.1 - 0.00026 21.5 0.2 0.00074 20.1 0.2 1.8 1 0 0 1 1 1 1 Excalibur calcium-binding domain Gmad2 PF10648.9 EGB07885.1 - 0.061 13.6 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination DER1 PF04511.15 EGB07886.1 - 2e-20 73.5 0.3 2.5e-20 73.2 0.3 1.0 1 0 0 1 1 1 1 Der1-like family DUF1011 PF06237.12 EGB07886.1 - 0.064 13.6 3.0 0.24 11.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) PIN_6 PF17146.4 EGB07887.1 - 3.1e-27 94.9 0.1 5e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EGB07887.1 - 2.4e-20 72.4 0.1 4.3e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like La PF05383.17 EGB07887.1 - 1.4e-08 34.7 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 La domain PIN PF01850.21 EGB07887.1 - 0.015 15.8 1.8 0.78 10.3 0.6 2.7 2 0 0 2 2 2 0 PIN domain SWIRM-assoc_2 PF16496.5 EGB07887.1 - 0.19 10.6 11.5 0.82 8.5 5.7 2.2 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Ephrin_rec_like PF07699.13 EGB07888.1 - 0.00011 21.9 2.2 0.00011 21.9 2.2 3.9 3 1 1 4 4 4 3 Putative ephrin-receptor like Tail_P2_I PF09684.10 EGB07888.1 - 0.18 11.8 0.5 0.47 10.4 0.5 1.7 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) TRP PF06011.12 EGB07888.1 - 0.58 8.8 8.2 0.96 8.1 8.2 1.4 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel LsmAD PF06741.13 EGB07889.1 - 2.1e-22 79.4 0.9 3.7e-22 78.7 0.9 1.4 1 0 0 1 1 1 1 LsmAD domain Methyltransf_21 PF05050.12 EGB07889.1 - 2.7e-06 27.5 0.0 7.3e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 EGB07889.1 - 0.00033 20.3 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PhyH PF05721.13 EGB07889.1 - 0.027 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) RRN3 PF05327.11 EGB07890.1 - 6.1e-51 173.6 0.1 1.3e-48 165.9 0.0 3.1 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 NUDIX PF00293.28 EGB07890.1 - 3e-08 33.8 0.0 1.7e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain OpuAC PF04069.12 EGB07890.1 - 1.1e-06 28.4 0.3 8.8e-05 22.2 0.1 2.3 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system Ephrin_rec_like PF07699.13 EGB07890.1 - 0.0007 19.3 7.9 0.0007 19.3 7.9 7.3 4 1 5 9 9 9 5 Putative ephrin-receptor like zf-C2H2 PF00096.26 EGB07890.1 - 0.0021 18.4 0.9 0.0066 16.9 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGB07890.1 - 0.13 13.2 4.2 0.1 13.5 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger His_Phos_1 PF00300.22 EGB07891.1 - 5e-06 26.3 0.1 5.4e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Reprolysin_5 PF13688.6 EGB07891.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EGB07891.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like His_Phos_1 PF00300.22 EGB07892.1 - 1.8e-30 106.1 0.0 2.1e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EGB07892.1 - 0.00065 19.2 0.0 0.00079 18.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Caudo_TAP PF02413.17 EGB07893.1 - 0.022 14.9 0.7 0.06 13.5 0.7 1.7 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Ribo_biogen_C PF04034.13 EGB07895.1 - 9.8e-44 148.1 0.0 1.2e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGB07895.1 - 0.0052 16.6 0.1 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI ABC_tran PF00005.27 EGB07898.1 - 4.1e-22 79.2 0.0 5.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB07898.1 - 4.9e-06 26.6 0.0 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB07898.1 - 0.00026 21.4 0.1 0.00041 20.8 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGB07898.1 - 0.0023 17.9 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EGB07898.1 - 0.0024 17.4 0.0 2.1 7.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGB07898.1 - 0.0034 17.9 0.0 0.0047 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB07898.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 EGB07898.1 - 0.018 14.7 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGB07898.1 - 0.04 14.2 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB07898.1 - 0.047 13.9 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGB07898.1 - 0.095 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 EGB07898.1 - 0.16 11.9 0.1 0.54 10.2 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EGB07898.1 - 0.27 10.9 0.0 0.4 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Phospholip_B PF04916.13 EGB07899.1 - 6.4e-119 397.9 0.0 7.1e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B PS_pyruv_trans PF04230.13 EGB07900.1 - 6.2e-15 55.9 0.0 1.6e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase Galactosyl_T PF01762.21 EGB07900.1 - 1.4e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase GMC_oxred_N PF00732.19 EGB07901.1 - 1.7e-69 234.4 0.0 2.3e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGB07901.1 - 4.6e-37 127.7 1.3 7.9e-37 127.0 1.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EGB07901.1 - 0.00062 19.9 0.1 0.0023 18.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGB07901.1 - 0.0027 16.8 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein LRR_8 PF13855.6 EGB07902.1 - 2.1e-37 126.7 0.3 1.1e-07 31.5 0.0 8.5 6 2 1 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EGB07902.1 - 1.1e-35 121.0 9.9 8e-06 26.1 0.0 11.0 8 4 3 12 12 12 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB07902.1 - 2.4e-08 33.7 0.0 0.00068 19.2 0.0 3.8 3 1 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EGB07902.1 - 3e-06 26.8 7.9 0.82 9.9 0.0 7.7 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 EGB07902.1 - 9e-06 25.6 18.4 18 6.3 0.1 12.5 14 2 0 14 14 14 1 Leucine Rich Repeat UPF0020 PF01170.18 EGB07903.1 - 9.3e-13 48.3 0.1 2.8e-07 30.4 0.4 2.6 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Nucleotid_trans PF03407.16 EGB07903.1 - 3.7e-06 27.1 0.0 6.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase N6_N4_Mtase PF01555.18 EGB07903.1 - 0.019 14.7 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 DNA methylase N6_Mtase PF02384.16 EGB07903.1 - 0.056 12.7 0.0 1.2 8.3 0.0 2.4 3 0 0 3 3 3 0 N-6 DNA Methylase SIR2 PF02146.17 EGB07904.1 - 2.3e-27 96.0 0.0 2.9e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGB07904.1 - 0.0013 18.4 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PH PF00169.29 EGB07905.1 - 0.00013 22.5 0.0 1.1 9.8 0.0 3.3 3 0 0 3 3 3 2 PH domain Chorein_N PF12624.7 EGB07905.1 - 0.00014 21.9 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 PH_6 PF15406.6 EGB07905.1 - 0.0087 16.3 0.1 4.6 7.6 0.0 3.6 3 0 0 3 3 3 2 Pleckstrin homology domain Glyco_hydro_79n PF03662.14 EGB07906.1 - 8.9e-24 84.0 0.0 9.7e-17 60.9 0.0 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain TPR_12 PF13424.6 EGB07908.1 - 0.00018 21.7 21.9 0.0002 21.5 5.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat RecO_C PF02565.15 EGB07908.1 - 0.0011 18.7 0.2 0.0025 17.7 0.2 1.6 1 0 0 1 1 1 1 Recombination protein O C terminal TPR_10 PF13374.6 EGB07908.1 - 0.057 13.3 24.2 0.12 12.3 2.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat FlaC_arch PF05377.11 EGB07910.1 - 4.2 7.9 10.1 36 4.9 0.1 6.0 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) Prp19 PF08606.11 EGB07912.1 - 0.066 13.2 3.6 0.062 13.3 1.8 1.9 1 1 1 2 2 2 0 Prp19/Pso4-like DUF4336 PF14234.6 EGB07913.1 - 5.5e-104 347.8 0.0 6.8e-104 347.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) Pkinase PF00069.25 EGB07914.1 - 1.3e-43 149.3 0.0 1.4e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07914.1 - 1.3e-25 90.2 0.0 1.4e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB07914.1 - 0.00028 20.3 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB07914.1 - 0.00065 19.7 1.6 0.013 15.4 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB07914.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB07914.1 - 0.018 13.8 0.0 0.03 13.1 0.0 1.3 2 0 0 2 2 2 0 Fungal protein kinase PAF-AH_p_II PF03403.13 EGB07915.1 - 6.1e-13 48.0 0.0 1.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGB07915.1 - 0.041 12.8 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Sugar_tr PF00083.24 EGB07916.1 - 2.1e-84 284.0 9.1 2.6e-84 283.7 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB07916.1 - 3.1e-12 46.1 30.6 3.1e-12 46.1 30.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily peroxidase PF00141.23 EGB07917.1 - 1.5e-43 149.2 0.0 2.6e-43 148.3 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Pyr_redox_2 PF07992.14 EGB07918.1 - 3.7e-39 134.7 1.7 5.1e-39 134.3 1.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB07918.1 - 5.2e-37 126.5 0.2 5.3e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB07918.1 - 2.1e-19 69.8 4.8 1.6e-12 47.8 0.2 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB07918.1 - 4.2e-05 22.8 3.7 0.001 18.2 1.5 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGB07918.1 - 6.4e-05 22.4 0.0 0.059 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGB07918.1 - 0.00049 20.5 0.7 0.28 11.6 0.1 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.7 EGB07918.1 - 0.00083 18.8 5.2 0.0014 18.1 2.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGB07918.1 - 0.00087 18.6 4.8 0.0093 15.2 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGB07918.1 - 0.0012 18.2 12.9 0.0073 15.6 0.4 3.4 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EGB07918.1 - 0.0014 17.7 1.6 0.018 14.1 0.4 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EGB07918.1 - 0.0019 17.8 1.5 0.0019 17.8 1.5 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase S4 PF01479.25 EGB07918.1 - 0.0055 16.4 0.1 5.4 6.8 0.0 2.7 2 0 0 2 2 2 2 S4 domain 3HCDH_N PF02737.18 EGB07918.1 - 0.0072 16.2 1.0 0.42 10.5 0.2 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 EGB07918.1 - 0.0095 15.2 1.2 0.028 13.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family XdhC_C PF13478.6 EGB07918.1 - 0.012 16.1 0.6 1.3 9.6 0.1 3.0 3 0 0 3 3 3 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 EGB07918.1 - 0.018 14.4 0.0 6.7 6.0 0.0 2.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EGB07918.1 - 0.023 13.4 0.6 0.057 12.1 0.6 1.7 1 0 0 1 1 1 0 HI0933-like protein KH_1 PF00013.29 EGB07918.1 - 0.029 14.2 0.0 0.09 12.6 0.0 1.8 1 0 0 1 1 1 0 KH domain NAD_binding_8 PF13450.6 EGB07918.1 - 0.029 14.6 3.1 0.28 11.5 0.6 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DHC PF09626.10 EGB07918.1 - 0.34 11.8 0.6 36 5.2 0.1 2.3 2 0 0 2 2 2 0 Dihaem cytochrome c TPR_1 PF00515.28 EGB07919.1 - 1.1e-32 110.5 31.2 0.00039 20.1 0.4 11.5 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07919.1 - 7.3e-29 97.5 36.9 0.0015 18.5 0.0 12.2 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_12 PF13424.6 EGB07919.1 - 2.7e-24 85.3 32.8 3e-05 24.2 0.0 10.1 5 2 6 11 11 11 8 Tetratricopeptide repeat TPR_6 PF13174.6 EGB07919.1 - 7e-21 73.4 14.2 0.0018 18.8 0.0 10.8 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB07919.1 - 5.1e-20 70.4 18.5 0.0065 17.2 0.0 11.2 7 4 4 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB07919.1 - 6.1e-20 69.7 8.8 0.0011 18.8 0.0 8.5 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGB07919.1 - 6.1e-18 65.1 13.6 0.00021 21.8 0.0 8.5 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07919.1 - 1e-17 62.8 21.6 0.22 11.8 0.0 11.3 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGB07919.1 - 1.2e-15 57.8 14.7 0.003 18.2 3.8 8.2 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB07919.1 - 1.1e-13 50.6 17.6 0.025 14.3 0.7 9.3 9 1 1 10 10 10 4 TPR repeat ANAPC3 PF12895.7 EGB07919.1 - 8.2e-13 48.4 21.8 8.2e-05 22.8 0.1 5.8 5 2 1 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGB07919.1 - 1.3e-10 41.2 0.7 0.074 13.2 0.0 6.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 EGB07919.1 - 6.3e-06 26.0 10.7 0.00018 21.2 2.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 EGB07919.1 - 7.7e-06 25.6 23.4 0.47 10.4 0.5 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGB07919.1 - 9.1e-06 25.7 14.9 1.4 9.4 0.1 8.9 10 1 1 11 11 10 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB07919.1 - 2.6e-05 24.2 2.6 1.3 9.2 0.0 5.7 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 EGB07919.1 - 0.0061 16.7 10.8 5.8 7.4 0.1 7.3 8 0 0 8 8 7 1 PPR repeat Foie-gras_1 PF11817.8 EGB07919.1 - 0.023 14.3 3.8 20 4.6 0.5 4.4 4 1 0 4 4 4 0 Foie gras liver health family 1 TPR_3 PF07720.12 EGB07919.1 - 0.039 14.0 13.9 1.9 8.6 1.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGB07919.1 - 0.14 12.5 9.9 21 5.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3808 PF10300.9 EGB07919.1 - 0.16 10.6 5.3 0.21 10.3 0.0 3.2 3 1 0 4 4 4 0 Protein of unknown function (DUF3808) HemY_N PF07219.13 EGB07919.1 - 3.8 7.8 9.7 2.1 8.6 0.6 3.5 3 0 0 3 3 3 0 HemY protein N-terminus CH PF00307.31 EGB07920.1 - 4.6e-11 42.9 0.4 9.6e-06 25.7 0.0 3.3 2 1 1 3 3 3 2 Calponin homology (CH) domain EF-hand_7 PF13499.6 EGB07920.1 - 4.1e-05 23.9 0.1 0.00015 22.1 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB07920.1 - 0.00017 21.2 0.1 0.00067 19.4 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain Spectrin PF00435.21 EGB07920.1 - 0.00019 21.9 9.0 0.43 11.1 0.0 7.1 6 2 0 6 6 6 2 Spectrin repeat EF-hand_1 PF00036.32 EGB07920.1 - 0.0008 18.8 0.1 0.0022 17.4 0.1 1.8 1 0 0 1 1 1 1 EF hand CAMSAP_CH PF11971.8 EGB07920.1 - 0.00094 19.0 0.0 0.0029 17.4 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain Methyltransf_30 PF05430.11 EGB07920.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF1515 PF07439.11 EGB07920.1 - 0.047 13.7 4.2 18 5.4 0.5 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) EF-hand_8 PF13833.6 EGB07920.1 - 0.24 11.3 0.5 0.82 9.6 0.2 2.0 1 1 1 2 2 2 0 EF-hand domain pair MnmE_helical PF12631.7 EGB07920.1 - 4.7 7.3 8.3 16 5.6 5.3 3.1 2 1 0 2 2 2 0 MnmE helical domain CLPTM1 PF05602.12 EGB07921.1 - 1.8e-81 274.3 0.3 2.2e-81 274.1 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EGB07921.1 - 3.4e-05 23.5 2.2 0.0085 15.8 0.2 2.8 2 1 0 2 2 2 2 PQ loop repeat FdhE PF04216.12 EGB07921.1 - 0.093 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation TMEM208_SND2 PF05620.11 EGB07921.1 - 0.12 12.1 1.6 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 HAD_2 PF13419.6 EGB07922.1 - 1.6e-26 93.5 0.0 1.8e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB07922.1 - 1.2e-17 64.9 0.2 4.5e-17 63.0 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB07922.1 - 4.4e-07 30.5 0.1 5.3e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB07922.1 - 1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EGB07922.1 - 0.007 16.5 0.1 0.14 12.3 0.1 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGB07922.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EGB07922.1 - 0.26 11.1 0.0 4.8 7.0 0.0 2.6 1 1 0 1 1 1 0 Acid Phosphatase SHIPPO-rpt PF07004.12 EGB07923.1 - 0.039 14.9 6.6 0.14 13.1 0.5 3.2 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat BT1 PF03092.16 EGB07924.1 - 4.3e-66 223.2 11.9 1.1e-35 122.8 2.1 2.0 1 1 1 2 2 2 2 BT1 family FG-GAP_2 PF14312.6 EGB07925.1 - 7.1e-116 378.4 75.3 3.9e-21 75.0 8.9 7.2 7 0 0 7 7 7 7 FG-GAP repeat BNR_2 PF13088.6 EGB07925.1 - 6.5e-05 22.4 0.3 0.029 13.7 0.0 2.7 1 1 0 2 2 2 2 BNR repeat-like domain Kelch_3 PF13415.6 EGB07925.1 - 0.00025 21.2 11.2 2.4 8.5 0.1 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Nmad4 PF18756.1 EGB07925.1 - 0.0019 18.5 0.3 41 4.6 0.0 4.4 3 2 2 5 5 5 0 Nucleotide modification associated domain 4 BNR PF02012.20 EGB07925.1 - 0.0027 17.5 19.8 0.61 10.3 0.6 5.4 4 0 0 4 4 4 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EGB07925.1 - 0.0087 14.9 10.1 2 7.1 1.8 3.8 3 1 1 4 4 4 3 Sortilin, neurotensin receptor 3, BNR_3 PF13859.6 EGB07925.1 - 0.13 11.6 0.7 5.1 6.3 0.3 2.8 1 1 1 2 2 2 0 BNR repeat-like domain PTE PF02126.18 EGB07925.1 - 0.13 11.6 0.1 12 5.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotriesterase family PsaX PF08078.12 EGB07925.1 - 0.14 12.1 10.7 7 6.7 0.1 5.5 6 0 0 6 6 6 0 PsaX family Vps23_core PF09454.10 EGB07925.1 - 0.24 11.4 0.2 54 3.8 0.0 3.0 3 0 0 3 3 3 0 Vps23 core domain Kelch_6 PF13964.6 EGB07925.1 - 0.28 11.5 16.0 6.1 7.3 0.1 6.0 7 0 0 7 7 7 0 Kelch motif SNF2_N PF00176.23 EGB07926.1 - 3.7e-66 223.2 0.2 6e-66 222.5 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB07926.1 - 5.3e-20 71.8 0.0 2.6e-19 69.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB07926.1 - 1.3e-09 38.3 0.0 4.1e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DBINO PF13892.6 EGB07926.1 - 4.3e-06 27.1 1.0 1.1e-05 25.7 1.0 1.7 1 0 0 1 1 1 1 DNA-binding domain DEAD PF00270.29 EGB07926.1 - 5.9e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EGB07926.1 - 0.0017 17.6 0.0 0.0059 15.8 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EGB07926.1 - 0.0017 18.0 0.0 0.0045 16.7 0.0 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase SNF2_N PF00176.23 EGB07927.1 - 1.1e-66 224.9 0.2 1.9e-66 224.2 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGB07927.1 - 7.5e-41 138.7 0.4 4.9e-40 136.1 0.2 2.4 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.31 EGB07927.1 - 1.3e-19 70.6 0.0 5.2e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB07927.1 - 1.9e-09 37.7 0.0 6.5e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 EGB07927.1 - 5.2e-08 33.0 1.0 0.00027 21.1 0.3 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain HAND PF09110.11 EGB07927.1 - 9.3e-08 32.8 2.7 1.9e-07 31.8 0.2 2.9 3 0 0 3 3 2 1 HAND DEAD PF00270.29 EGB07927.1 - 1.5e-05 24.8 0.0 3.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 EGB07927.1 - 2e-05 24.9 1.0 2e-05 24.9 1.0 3.2 4 0 0 4 4 3 1 DNA-binding domain HDA2-3 PF11496.8 EGB07927.1 - 0.0033 16.6 0.0 0.0089 15.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EGB07927.1 - 0.0037 17.0 0.0 0.0094 15.6 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Myb_DNA-bind_6 PF13921.6 EGB07927.1 - 0.015 15.5 2.4 0.029 14.6 0.8 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain CAP_GLY PF01302.25 EGB07928.1 - 7.8e-21 73.9 0.0 8.1e-21 73.8 0.0 1.0 1 0 0 1 1 1 1 CAP-Gly domain Actin PF00022.19 EGB07929.1 - 1.1e-146 488.6 0.0 3.6e-146 487.0 0.0 1.6 1 1 0 1 1 1 1 Actin BT1 PF03092.16 EGB07930.1 - 7.9e-11 40.9 8.4 3.1e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 BT1 family CitMHS PF03600.16 EGB07930.1 - 0.0055 15.9 4.1 0.047 12.9 2.5 2.2 2 0 0 2 2 2 1 Citrate transporter PGAP1 PF07819.13 EGB07930.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Sel1 PF08238.12 EGB07931.1 - 1.2e-19 70.3 13.8 4.8e-07 30.2 0.2 4.1 4 0 0 4 4 4 4 Sel1 repeat TPR_6 PF13174.6 EGB07931.1 - 0.017 15.8 2.7 0.73 10.6 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGB07931.1 - 0.086 12.9 0.9 0.62 10.2 0.1 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 EGB07932.1 - 4.3e-47 160.7 0.0 5.1e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07932.1 - 3.7e-27 95.2 0.0 4.4e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB07932.1 - 6.1e-08 32.9 0.1 0.0017 18.3 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB07932.1 - 2.5e-07 30.3 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB07932.1 - 0.00025 20.1 0.0 0.00035 19.6 0.0 1.2 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB07932.1 - 0.074 12.4 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like ABC_tran PF00005.27 EGB07933.1 - 3.6e-21 76.1 0.0 5.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGB07933.1 - 0.00051 19.7 0.1 0.0016 18.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB07933.1 - 0.00051 20.3 0.0 0.00086 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB07933.1 - 0.00066 20.1 0.9 0.0013 19.2 0.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB07933.1 - 0.00077 19.3 0.1 0.48 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB07933.1 - 0.0032 17.4 0.0 0.0087 16.0 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EGB07933.1 - 0.0039 16.8 0.5 0.0075 15.9 0.5 1.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGB07933.1 - 0.005 16.3 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 EGB07933.1 - 0.016 14.2 0.1 0.031 13.2 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGB07933.1 - 0.04 13.6 0.1 0.067 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB07933.1 - 0.075 12.9 0.2 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EGB07933.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB07933.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain Virul_Fac PF10139.9 EGB07933.1 - 0.12 10.5 0.2 0.16 10.1 0.2 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor cobW PF02492.19 EGB07933.1 - 0.13 11.9 0.4 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EGB07933.1 - 0.19 12.3 0.0 0.38 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGB07933.1 - 0.25 11.1 0.1 0.41 10.4 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DAO PF01266.24 EGB07934.1 - 8.1e-64 216.4 4.7 8.1e-64 216.4 4.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GCV_T PF01571.21 EGB07934.1 - 6.4e-59 199.4 0.0 9.6e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGB07934.1 - 1.3e-18 66.7 0.8 5.2e-18 64.7 0.8 2.2 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 EGB07934.1 - 3.8e-13 49.6 0.1 8.6e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 EGB07934.1 - 1.3e-06 27.8 0.4 0.00062 19.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB07934.1 - 5.3e-06 25.8 3.6 6.9e-05 22.1 3.6 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGB07934.1 - 4.5e-05 23.6 0.3 0.00014 22.0 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGB07934.1 - 6e-05 22.5 0.7 0.00087 18.6 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGB07934.1 - 7.2e-05 22.1 1.2 0.018 14.3 0.1 2.3 2 0 0 2 2 2 2 Thi4 family ApbA PF02558.16 EGB07934.1 - 0.00093 18.9 0.1 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EGB07934.1 - 0.00096 18.1 1.1 0.42 9.4 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGB07934.1 - 0.011 15.1 0.0 0.052 12.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB07934.1 - 0.014 16.0 0.1 0.042 14.4 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB07934.1 - 0.017 14.2 0.7 0.39 9.7 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EGB07934.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.19 EGB07934.1 - 0.037 13.4 0.2 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase FAD_oxidored PF12831.7 EGB07934.1 - 0.046 13.1 2.2 0.25 10.6 2.2 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGB07934.1 - 0.084 12.9 1.6 0.78 9.7 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EGB07934.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EGB07934.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupin_8 PF13621.6 EGB07936.1 - 1.2e-38 133.3 0.0 1.5e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB07936.1 - 7e-13 48.7 0.3 1.6e-12 47.5 0.3 1.5 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB07936.1 - 0.0032 17.2 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 EGB07936.1 - 0.052 14.0 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 JmjC domain, hydroxylase Ribosomal_L12_N PF16320.5 EGB07936.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain ARD PF03079.14 EGB07936.1 - 0.24 11.5 0.0 0.38 10.9 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Epimerase PF01370.21 EGB07937.1 - 4.3e-15 55.8 1.0 1.3e-14 54.3 1.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGB07937.1 - 1.4e-09 37.5 1.8 2.4e-08 33.4 1.8 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGB07937.1 - 1.7e-07 30.6 1.1 5.4e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EGB07937.1 - 1.8e-05 23.9 0.0 3.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGB07937.1 - 0.0015 17.7 2.9 0.082 12.0 0.2 3.3 4 0 0 4 4 4 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGB07937.1 - 0.031 13.7 7.5 4.1 6.7 3.4 3.7 3 1 0 3 3 3 0 GDP-mannose 4,6 dehydratase Fringe PF02434.16 EGB07938.1 - 7.3e-06 25.6 0.0 0.00012 21.6 0.0 2.0 1 1 0 1 1 1 1 Fringe-like Pertussis_S2S3 PF02918.15 EGB07938.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain DUF2322 PF10084.9 EGB07938.1 - 0.2 11.7 0.1 0.34 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) HAD PF12710.7 EGB07939.1 - 2e-12 47.9 0.1 4.7e-12 46.7 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB07939.1 - 3.3e-11 43.9 0.5 4.6e-11 43.4 0.5 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.32 EGB07940.1 - 4.7e-20 69.6 7.4 0.00021 20.6 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB07940.1 - 3.2e-19 67.1 3.6 9.9e-05 22.0 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGB07940.1 - 3.1e-16 59.6 1.9 2e-07 31.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB07940.1 - 1.1e-14 53.1 8.4 0.00012 21.4 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB07940.1 - 1.6e-10 40.7 15.4 0.0005 19.9 1.0 4.1 2 2 2 4 4 4 4 EF-hand domain pair Excalibur PF05901.11 EGB07940.1 - 0.011 16.3 0.1 0.52 11.0 0.0 2.5 2 0 0 2 2 2 0 Excalibur calcium-binding domain zf-CCHC_5 PF14787.6 EGB07940.1 - 0.42 10.4 4.3 6 6.7 1.3 2.8 2 1 0 2 2 2 0 GAG-polyprotein viral zinc-finger PMI_typeI PF01238.21 EGB07941.1 - 3.5e-85 286.4 0.0 3.1e-84 283.3 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Ras PF00071.22 EGB07942.1 - 2.3e-35 121.6 0.1 2.6e-35 121.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB07942.1 - 2.4e-18 66.5 0.0 3e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB07942.1 - 5e-06 26.1 0.0 6.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB07942.1 - 0.00033 20.7 0.0 0.00048 20.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGB07942.1 - 0.0017 17.7 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGB07942.1 - 0.034 14.5 0.0 0.039 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EGB07942.1 - 0.097 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein Pkinase PF00069.25 EGB07943.1 - 8e-42 143.4 0.0 9.3e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07943.1 - 5e-22 78.4 0.0 1.4e-21 77.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB07943.1 - 0.00028 20.3 0.0 0.00065 19.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB07943.1 - 0.0015 18.5 0.1 0.0033 17.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB07943.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family PT PF04886.12 EGB07944.1 - 0.0035 16.9 15.3 0.0035 16.9 15.3 4.3 2 2 1 3 3 3 2 PT repeat YbfN PF13982.6 EGB07944.1 - 0.023 15.0 0.0 0.26 11.6 0.1 2.2 2 0 0 2 2 2 0 YbfN-like lipoprotein Claudin_3 PF06653.11 EGB07944.1 - 0.38 10.7 2.6 3.3 7.6 0.1 2.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like TRP PF06011.12 EGB07944.1 - 2.8 6.6 7.6 0.29 9.8 2.2 1.9 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel UPF0444 PF15475.6 EGB07945.1 - 0.12 12.6 2.2 0.61 10.4 2.2 2.2 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Sel1 PF08238.12 EGB07946.1 - 5.8e-22 77.6 14.3 2.2e-08 34.5 0.4 4.2 4 0 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB07946.1 - 0.024 15.3 8.1 0.11 13.1 3.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB07946.1 - 0.039 14.3 5.1 0.085 13.2 0.5 3.3 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB07946.1 - 0.099 12.5 0.2 0.099 12.5 0.2 4.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB07946.1 - 0.2 11.9 0.5 0.2 11.9 0.5 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB07946.1 - 0.46 10.8 0.1 0.46 10.8 0.1 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EGB07946.1 - 9.7 6.3 8.6 4.4 7.4 0.6 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DEAD PF00270.29 EGB07947.1 - 3.1e-44 150.8 0.0 7.5e-44 149.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB07947.1 - 2.1e-30 105.3 0.0 5e-28 97.7 0.0 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGB07947.1 - 7.8e-05 22.7 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGB07947.1 - 0.045 12.9 0.0 0.098 11.9 0.0 1.5 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EGB07947.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain PKcGMP_CC PF16808.5 EGB07948.1 - 8.1e-06 25.6 0.5 0.0027 17.5 0.3 2.6 1 1 1 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.5 EGB07948.1 - 1 8.7 18.3 1.5 8.1 18.3 1.2 1 0 0 1 1 1 0 FAM76 protein RNase_HII PF01351.18 EGB07949.1 - 2e-20 73.5 0.1 1e-10 41.8 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII Beta_helix PF13229.6 EGB07950.1 - 1.1e-10 41.6 3.7 4.3e-06 26.7 0.1 4.5 3 1 3 6 6 6 5 Right handed beta helix region DUF4059 PF13268.6 EGB07950.1 - 0.049 14.0 0.4 0.14 12.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) NosD PF05048.13 EGB07950.1 - 0.055 12.7 3.6 2.4 7.4 0.1 3.1 3 1 1 4 4 4 0 Periplasmic copper-binding protein (NosD) lci PF12197.8 EGB07950.1 - 0.079 12.8 2.4 6.1 6.7 0.2 3.1 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein Peptidase_C2 PF00648.21 EGB07951.1 - 1.7e-25 89.7 0.0 1.9e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Ribosomal_S26e PF01283.19 EGB07952.1 - 2.3e-32 111.6 3.4 2.5e-32 111.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e WD40 PF00400.32 EGB07953.1 - 2.8e-07 31.1 7.4 0.021 15.7 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.6 EGB07953.1 - 0.0021 18.5 3.4 0.83 10.2 0.4 4.0 5 1 1 6 6 6 2 PQQ-like domain CAF1 PF04857.20 EGB07953.1 - 0.043 13.0 0.1 0.053 12.7 0.1 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF1035 PF06281.12 EGB07953.1 - 0.099 12.7 0.2 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) Nup160 PF11715.8 EGB07953.1 - 0.12 11.0 0.1 4.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 KGG PF10685.9 EGB07953.1 - 0.33 11.3 1.9 0.71 10.2 1.9 1.6 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif PQQ PF01011.21 EGB07953.1 - 0.68 10.0 2.2 36 4.5 0.2 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Aldo_ket_red PF00248.21 EGB07954.1 - 2.6e-30 105.6 0.0 3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TMEM107 PF14995.6 EGB07955.1 - 0.081 13.4 1.8 0.17 12.3 1.8 1.5 1 0 0 1 1 1 0 Transmembrane protein ArAE_2_N PF10337.9 EGB07955.1 - 0.42 9.6 3.1 0.79 8.7 3.1 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal HSF_DNA-bind PF00447.17 EGB07956.1 - 5.8e-19 68.5 0.0 6.6e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding PD40 PF07676.12 EGB07956.1 - 0.00064 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat Thioredoxin_4 PF13462.6 EGB07957.1 - 1.2e-08 35.3 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EGB07957.1 - 0.28 10.9 6.1 1.3 8.7 0.9 2.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Glyco_transf_8 PF01501.20 EGB07958.1 - 5.5e-21 75.3 0.0 9.1e-21 74.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 EGB07958.1 - 0.0078 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Glucosyltransferase 24 Arylsulfotran_2 PF14269.6 EGB07960.1 - 2.1e-05 24.1 0.1 3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EGB07960.1 - 3.3e-05 23.0 0.0 5.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DENN PF02141.21 EGB07961.1 - 1.9e-13 50.8 0.0 2.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain Cwf_Cwc_15 PF04889.12 EGB07961.1 - 1.2 8.8 3.4 0.93 9.2 0.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein UCH PF00443.29 EGB07962.1 - 1.7e-24 86.7 0.0 2.1e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB07962.1 - 9.1e-07 28.8 0.0 1.7e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-piccolo PF05715.13 EGB07962.1 - 0.00087 19.4 0.3 0.07 13.3 0.0 2.4 2 0 0 2 2 2 1 Piccolo Zn-finger Ank_2 PF12796.7 EGB07963.1 - 6.2e-23 81.2 0.6 2.5e-10 40.8 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGB07963.1 - 8.2e-23 79.8 4.8 4.1e-05 23.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EGB07963.1 - 3.7e-21 75.2 4.3 3e-11 43.6 0.1 3.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB07963.1 - 6.8e-17 61.3 3.7 1.7e-07 31.4 0.1 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB07963.1 - 1e-15 56.2 0.7 0.00059 20.1 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat IMPDH PF00478.25 EGB07964.1 - 2e-129 431.6 4.6 2.3e-129 431.3 4.6 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EGB07964.1 - 2.8e-13 50.1 0.2 6.3e-07 29.8 0.0 3.4 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 EGB07964.1 - 1.7e-12 47.4 1.9 5.1e-06 26.1 0.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EGB07964.1 - 3.2e-08 33.0 1.7 8e-08 31.7 1.8 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EGB07964.1 - 3.8e-05 23.1 0.9 7e-05 22.2 0.5 1.7 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EGB07964.1 - 0.00034 20.2 1.8 0.0074 15.8 1.8 2.5 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 EGB07964.1 - 0.083 12.1 0.3 0.19 10.9 0.3 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase LEA_2 PF03168.13 EGB07964.1 - 0.13 12.8 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein NanE PF04131.14 EGB07964.1 - 0.21 10.8 1.4 3 7.0 1.4 2.9 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 EGB07964.1 - 0.21 10.7 2.6 0.6 9.2 2.1 1.9 2 0 0 2 2 2 0 Conserved region in glutamate synthase Ribosomal_L1 PF00687.21 EGB07965.1 - 1.4e-46 158.9 0.0 2.2e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family CAP PF00188.26 EGB07966.1 - 1.7e-06 28.9 0.0 3.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4611 PF15387.6 EGB07966.1 - 0.067 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) cNMP_binding PF00027.29 EGB07967.1 - 1.1e-06 28.6 0.0 2.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB07967.1 - 4e-06 26.2 2.7 2.7e-05 23.5 0.8 2.1 2 0 0 2 2 2 1 Ion transport protein CK2S PF15011.6 EGB07967.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF5587 PF17825.1 EGB07967.1 - 0.18 9.1 0.0 0.24 8.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5587) LapA_dom PF06305.11 EGB07967.1 - 0.4 10.5 2.1 1.2 9.0 0.2 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Abhydrolase_1 PF00561.20 EGB07968.1 - 3.9e-05 23.4 0.0 0.24 11.0 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB07968.1 - 0.0025 17.1 0.0 0.58 9.4 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGB07968.1 - 0.0061 16.1 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGB07968.1 - 0.044 13.6 0.1 0.073 12.9 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGB07968.1 - 0.11 12.3 0.0 1.4 8.6 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF818 PF05677.12 EGB07968.1 - 0.17 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Sec23_trunk PF04811.15 EGB07969.1 - 2.6e-66 223.7 0.0 3.8e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGB07969.1 - 1.6e-30 104.9 0.0 4.2e-30 103.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGB07969.1 - 1.2e-15 58.0 0.0 2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGB07969.1 - 4.6e-15 55.4 6.1 7.5e-15 54.7 6.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGB07969.1 - 1.8e-08 34.1 0.0 8.2e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat HATPase_c PF02518.26 EGB07971.1 - 2e-24 86.3 0.0 3.2e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGB07971.1 - 4.3e-17 62.3 0.1 1.4e-16 60.7 0.1 1.9 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGB07971.1 - 9.5e-08 32.0 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SAP PF02037.27 EGB07971.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain LRR_6 PF13516.6 EGB07972.1 - 2.7e-05 23.9 8.7 0.074 13.1 0.1 5.0 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 EGB07972.1 - 0.01 16.3 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) D-ser_dehydrat PF14031.6 EGB07973.1 - 2.1e-24 86.0 3.2 8.4e-24 84.1 0.2 3.0 2 2 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EGB07973.1 - 1.6e-23 83.5 0.2 2e-23 83.2 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EGB07974.1 - 1.4e-30 106.0 0.0 1.9e-14 54.3 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily BT1 PF03092.16 EGB07974.1 - 1.1e-28 99.7 11.7 8.4e-15 54.0 4.0 2.2 2 0 0 2 2 2 2 BT1 family 2OG-FeII_Oxy_4 PF13661.6 EGB07974.1 - 6.2e-10 39.6 0.0 0.00088 19.9 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EGB07974.1 - 4.8e-08 33.3 0.0 0.012 16.0 0.0 2.6 2 0 0 2 2 2 2 Putative 2OG-Fe(II) oxygenase UIM PF02809.20 EGB07974.1 - 2.7e-05 23.8 15.3 0.069 13.1 3.3 3.9 3 0 0 3 3 3 2 Ubiquitin interaction motif BNR_2 PF13088.6 EGB07975.1 - 6.3e-07 29.0 0.0 0.013 14.8 0.0 2.4 2 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EGB07975.1 - 0.00013 21.4 6.8 0.5 10.6 0.2 4.4 4 0 0 4 4 4 3 BNR/Asp-box repeat Sulfotransfer_4 PF17784.1 EGB07976.1 - 7.1e-52 176.3 0.0 8.5e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB07976.1 - 0.047 14.1 0.0 2.4 8.5 0.0 2.4 1 1 1 2 2 2 0 Sulfotransferase family Bestrophin PF01062.21 EGB07977.1 - 1.1e-24 87.3 0.1 2.5e-24 86.2 0.0 1.5 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel CCD48 PF15799.5 EGB07977.1 - 0.28 9.4 1.5 0.43 8.8 1.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 HMG_box PF00505.19 EGB07978.1 - 7.6e-20 71.1 0.1 7.6e-20 71.1 0.1 1.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB07978.1 - 4.7e-12 46.3 0.1 6.4e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 EGB07978.1 - 0.1 12.6 1.2 0.35 10.9 0.2 2.0 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Abhydrolase_6 PF12697.7 EGB07979.1 - 4.2e-11 43.9 6.4 5.7e-11 43.4 6.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB07979.1 - 1.7e-09 37.7 0.0 9.4e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB07979.1 - 4.6e-05 22.8 0.0 0.00011 21.5 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGB07979.1 - 0.00011 22.0 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 EGB07979.1 - 0.017 13.8 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Ndr family Thioesterase PF00975.20 EGB07979.1 - 0.041 14.0 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EGB07979.1 - 0.21 11.3 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.21 EGB07980.1 - 9.3e-23 80.9 0.1 1.2e-22 80.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB07980.1 - 6.9e-16 58.1 0.0 8e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGB07980.1 - 3.7e-15 56.1 0.0 8.8e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGB07980.1 - 1.9e-14 53.4 0.0 1.8e-13 50.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGB07980.1 - 3.2e-12 46.7 0.4 4.4e-12 46.3 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGB07980.1 - 5.7e-11 42.4 0.6 9.1e-11 41.7 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EGB07980.1 - 4.4e-05 22.8 0.3 6e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EGB07980.1 - 0.00073 19.1 1.5 0.0015 18.0 1.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB07980.1 - 0.002 18.1 1.6 0.0035 17.3 1.6 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EGB07980.1 - 0.02 14.0 0.5 0.049 12.7 0.5 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 EGB07980.1 - 0.04 13.8 0.7 0.057 13.3 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SpoU_sub_bind PF08032.12 EGB07980.1 - 0.062 13.6 0.1 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DapB_N PF01113.20 EGB07980.1 - 0.064 13.4 0.3 0.18 11.9 0.2 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus VDE PF07137.11 EGB07981.1 - 1.4e-75 253.9 0.0 1.9e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 VDE lipocalin domain Biotin_lipoyl PF00364.22 EGB07981.1 - 5.9e-07 29.2 0.1 4.3e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGB07981.1 - 0.0013 18.5 0.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like Lipocalin PF00061.23 EGB07981.1 - 0.0044 17.2 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family HlyD_3 PF13437.6 EGB07981.1 - 0.013 16.2 0.1 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 HlyD family secretion protein Glycos_transf_2 PF00535.26 EGB07981.1 - 0.14 11.9 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Pkinase PF00069.25 EGB07982.1 - 4.6e-21 75.4 0.0 5.1e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07982.1 - 1.3e-14 54.2 0.0 1.7e-14 53.7 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB07982.1 - 0.05 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB07982.1 - 0.083 12.8 0.8 0.74 9.7 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGB07983.1 - 8.4e-46 156.5 0.0 1.4e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB07983.1 - 3.3e-25 88.8 0.0 1.1e-23 83.8 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase RRM_1 PF00076.22 EGB07983.1 - 9.5e-14 51.0 0.0 2.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 EGB07983.1 - 7.5e-09 36.0 7.5 1.4e-08 35.1 6.9 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Kdo PF06293.14 EGB07983.1 - 0.049 13.0 0.1 0.35 10.2 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_Mx PF15887.5 EGB07983.1 - 0.052 12.9 0.3 0.094 12.1 0.3 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Suv3_N PF18114.1 EGB07983.1 - 0.16 12.1 1.2 0.3 11.2 0.2 2.0 2 0 0 2 2 2 0 Suv3 helical N-terminal domain RRM_1 PF00076.22 EGB07984.1 - 2.3e-15 56.2 0.0 2.4e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB07984.1 - 0.0076 16.1 0.0 0.012 15.4 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_8 PF11835.8 EGB07984.1 - 0.044 14.0 0.1 0.08 13.2 0.1 1.5 1 1 0 1 1 1 0 RRM-like domain RRM_5 PF13893.6 EGB07984.1 - 0.044 13.4 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGB07984.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_S26e PF01283.19 EGB07985.1 - 4.5e-47 158.9 8.6 5e-47 158.8 8.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e NAD_binding_2 PF03446.15 EGB07986.1 - 1.6e-40 138.9 4.0 2.1e-40 138.5 4.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGB07986.1 - 8e-31 106.8 1.7 9.7e-30 103.3 0.1 2.3 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGB07986.1 - 0.00034 21.1 0.6 0.00097 19.7 0.6 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EGB07986.1 - 0.04 12.9 0.7 0.059 12.3 0.7 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_10 PF13460.6 EGB07986.1 - 1.2 9.1 8.1 3 7.7 4.7 2.2 1 1 0 2 2 2 0 NAD(P)H-binding LRR_9 PF14580.6 EGB07987.1 - 1.7e-07 30.9 0.9 3.8e-07 29.8 0.9 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGB07987.1 - 3.9e-06 27.1 12.3 8e-05 22.9 3.8 3.0 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB07987.1 - 1.4e-05 24.7 17.6 0.00079 19.1 5.8 2.5 2 1 1 3 3 3 2 Leucine rich repeat PIH1_CS PF18201.1 EGB07987.1 - 0.046 14.1 0.0 0.18 12.2 0.0 2.0 2 1 0 2 2 2 0 PIH1 CS-like domain MIase PF02426.16 EGB07987.1 - 0.056 13.6 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Muconolactone delta-isomerase RR_TM4-6 PF06459.12 EGB07987.1 - 0.18 11.6 4.0 0.32 10.8 4.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_6 PF13516.6 EGB07987.1 - 0.29 11.3 2.8 8.3 6.7 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Tropomodulin PF03250.14 EGB07987.1 - 0.34 10.9 5.3 0.87 9.6 5.3 1.6 1 0 0 1 1 1 0 Tropomodulin PrmA PF06325.13 EGB07988.1 - 3.3e-07 30.0 3.4 6.9e-07 28.9 3.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGB07988.1 - 0.00011 22.9 0.4 0.00036 21.2 0.4 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGB07988.1 - 0.00043 20.2 0.1 0.00073 19.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB07988.1 - 0.00055 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB07988.1 - 0.0033 16.8 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EGB07988.1 - 0.0054 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGB07988.1 - 0.014 14.9 0.3 0.028 14.0 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EGB07988.1 - 0.016 15.0 0.3 0.032 14.0 0.3 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.6 EGB07988.1 - 0.033 15.2 1.7 0.13 13.3 0.2 2.8 3 0 0 3 3 2 0 Methyltransferase domain EF-hand_1 PF00036.32 EGB07988.1 - 0.06 12.9 0.0 0.06 12.9 0.0 3.0 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 EGB07988.1 - 0.073 13.5 0.0 0.27 11.7 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain pair FtsJ PF01728.19 EGB07988.1 - 0.1 12.7 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase EF-hand_6 PF13405.6 EGB07988.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.3 3 0 0 3 3 1 0 EF-hand domain Methyltransf_3 PF01596.17 EGB07988.1 - 0.14 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase EF-hand_8 PF13833.6 EGB07988.1 - 0.62 9.9 1.7 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair IBN_N PF03810.19 EGB07989.1 - 6.7e-07 29.1 0.3 1.9e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EGB07989.1 - 0.045 13.3 2.0 12 5.4 0.0 4.9 5 1 1 6 6 6 0 CLASP N terminal ABC2_membrane PF01061.24 EGB07990.1 - 3.6e-77 258.5 46.5 1.7e-34 119.1 12.7 3.5 3 0 0 3 3 3 3 ABC-2 type transporter ABC_tran PF00005.27 EGB07990.1 - 9.6e-34 116.8 0.0 1.6e-14 54.6 0.0 3.6 3 0 0 3 3 3 3 ABC transporter AAA_16 PF13191.6 EGB07990.1 - 0.00049 20.5 0.1 0.39 11.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB07990.1 - 0.00063 20.0 0.0 0.55 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGB07990.1 - 0.00071 19.7 0.5 2.3 8.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 EGB07990.1 - 0.00075 18.7 8.9 0.00075 18.7 8.9 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein TsaE PF02367.17 EGB07990.1 - 0.002 18.2 1.3 0.29 11.1 0.2 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EGB07990.1 - 0.0088 15.6 4.0 0.83 9.2 0.2 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGB07990.1 - 0.01 15.8 1.0 1.2 9.0 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EGB07990.1 - 0.014 15.9 0.9 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGB07990.1 - 0.056 13.2 1.5 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB07990.1 - 0.096 13.2 0.1 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB07990.1 - 0.11 12.4 1.3 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 EGB07990.1 - 0.11 12.8 1.7 3.7 7.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGB07990.1 - 0.13 12.4 0.4 5 7.2 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EGB07990.1 - 0.18 11.6 0.3 5.3 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGB07990.1 - 0.2 11.4 2.7 8.6 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGB07990.1 - 0.34 11.4 1.3 1.8 9.0 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PDR_CDR PF06422.12 EGB07990.1 - 0.37 10.7 4.7 0.49 10.3 0.3 2.8 3 0 0 3 3 2 0 CDR ABC transporter AAA_29 PF13555.6 EGB07990.1 - 0.57 10.0 7.3 2 8.2 1.4 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 EGB07990.1 - 1.2 8.7 3.8 15 5.1 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF21 PF01595.20 EGB07991.1 - 5.1e-26 91.4 0.2 1e-25 90.5 0.2 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGB07991.1 - 5.4e-16 58.8 3.4 1.4e-07 31.8 0.3 2.8 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.17 EGB07991.1 - 1.5e-13 50.6 0.1 3.8e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Transporter associated domain L_biotic_typeA PF04604.13 EGB07991.1 - 0.0029 17.4 0.7 0.039 13.8 0.9 2.4 2 0 0 2 2 2 1 Type-A lantibiotic P5CR_dimer PF14748.6 EGB07992.1 - 1.4e-40 137.7 2.6 1.4e-40 137.7 2.6 2.6 3 1 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGB07992.1 - 4.2e-16 59.3 1.8 4.2e-16 59.3 1.8 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGB07992.1 - 0.00093 19.4 0.7 0.0018 18.5 0.7 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EGB07992.1 - 0.0036 16.7 0.1 0.0076 15.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGB07992.1 - 0.0061 16.2 1.4 0.025 14.2 1.4 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PDH PF02153.17 EGB07992.1 - 0.036 13.1 0.2 0.056 12.4 0.2 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Shikimate_DH PF01488.20 EGB07992.1 - 0.059 13.4 0.6 0.15 12.1 0.6 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Metallophos PF00149.28 EGB07994.1 - 3.5e-09 37.4 0.0 1.5e-08 35.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB07994.1 - 5.5e-06 26.7 0.1 0.0016 18.7 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain LRR_8 PF13855.6 EGB07995.1 - 8.6e-29 99.1 14.3 7.2e-12 44.9 0.2 4.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGB07995.1 - 1e-18 67.1 4.4 2.5e-06 27.7 0.0 4.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB07995.1 - 5.2e-10 38.5 2.6 1.7 9.5 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 EGB07995.1 - 9.1e-07 28.4 3.4 6.8 7.0 0.0 4.8 5 0 0 5 5 5 4 Leucine Rich repeat NqrM PF04400.13 EGB07995.1 - 0.12 12.1 0.0 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM Sulfatase PF00884.23 EGB07996.1 - 3e-44 151.7 0.2 5e-44 150.9 0.2 1.4 1 0 0 1 1 1 1 Sulfatase ABC_tran PF00005.27 EGB07996.1 - 2.1e-18 67.2 0.0 3.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGB07996.1 - 2.9e-11 43.2 2.5 4.8e-11 42.5 2.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter Sulfatase_C PF14707.6 EGB07996.1 - 0.00026 21.7 0.0 0.00047 20.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 EGB07996.1 - 0.00066 19.6 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function AAA_21 PF13304.6 EGB07996.1 - 0.0051 16.7 0.8 3.2 7.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGB07996.1 - 0.035 13.7 2.0 0.08 12.5 0.6 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGB07996.1 - 0.035 14.0 0.3 0.062 13.2 0.3 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EGB07996.1 - 0.041 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB07996.1 - 0.054 13.8 0.1 0.41 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB07996.1 - 0.081 12.6 1.8 4.9 6.8 0.6 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 EGB07996.1 - 0.092 11.8 2.6 0.15 11.2 2.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_16 PF13191.6 EGB07996.1 - 0.69 10.3 6.5 0.091 13.1 1.1 2.3 3 0 0 3 3 3 0 AAA ATPase domain zf-RING_2 PF13639.6 EGB07997.1 - 0.0026 18.1 3.2 0.0061 16.9 3.2 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGB07997.1 - 0.022 14.6 0.2 0.044 13.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB07997.1 - 0.025 14.6 0.7 0.048 13.6 0.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB07997.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Ribosomal_L14e PF01929.17 EGB07997.1 - 0.57 10.7 2.5 1.1 9.8 0.5 2.1 2 0 0 2 2 2 0 Ribosomal protein L14 Peptidase_M41 PF01434.18 EGB07998.1 - 4.3e-53 180.0 0.1 7.2e-53 179.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGB07998.1 - 6.7e-44 149.5 0.0 1.4e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB07998.1 - 2e-12 46.7 0.3 1e-11 44.4 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EGB07998.1 - 6.2e-05 23.4 0.1 0.0018 18.7 0.0 3.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGB07998.1 - 0.00026 20.8 0.0 0.0007 19.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGB07998.1 - 0.00058 19.2 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 EGB07998.1 - 0.0014 18.9 2.4 0.064 13.5 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGB07998.1 - 0.0028 17.6 0.2 0.021 14.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGB07998.1 - 0.0049 17.0 0.0 0.025 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGB07998.1 - 0.0057 17.1 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGB07998.1 - 0.0072 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGB07998.1 - 0.039 14.2 0.1 0.25 11.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGB07998.1 - 0.049 13.4 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGB07998.1 - 0.058 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGB07998.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGB07998.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsH_ext PF06480.15 EGB07998.1 - 0.16 12.4 0.0 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 FtsH Extracellular Cyt-b5 PF00173.28 EGB07999.1 - 4.2e-17 62.1 0.1 6.4e-17 61.5 0.1 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA PF00004.29 EGB08000.1 - 5.4e-31 107.8 0.0 6.9e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB08000.1 - 2.3e-06 28.1 0.1 0.00015 22.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGB08000.1 - 1.5e-05 24.8 0.0 3.4e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGB08000.1 - 4.7e-05 22.7 0.1 8.6e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EGB08000.1 - 0.00018 21.5 0.3 0.0019 18.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGB08000.1 - 0.0005 20.2 0.0 0.00077 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EGB08000.1 - 0.00065 20.1 0.1 0.00086 19.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB08000.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB08000.1 - 0.0014 18.9 0.1 0.016 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGB08000.1 - 0.0027 18.0 0.1 0.0043 17.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGB08000.1 - 0.0035 16.8 0.1 0.012 15.0 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGB08000.1 - 0.0095 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 EGB08000.1 - 0.0096 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EGB08000.1 - 0.022 14.5 0.0 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 EGB08000.1 - 0.023 15.2 0.1 0.032 14.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EGB08000.1 - 0.027 14.2 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 EGB08000.1 - 0.029 14.1 0.1 0.048 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB08000.1 - 0.03 14.3 0.1 0.056 13.4 0.0 1.4 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EGB08000.1 - 0.045 13.2 0.1 0.075 12.5 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 EGB08000.1 - 0.099 12.2 0.1 0.61 9.6 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 EGB08000.1 - 0.12 11.6 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EGB08000.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Peptidase_M41 PF01434.18 EGB08001.1 - 4.9e-22 78.7 0.0 7.1e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 EGB08001.1 - 1e-12 47.6 0.1 1e-12 47.6 0.1 2.0 3 0 0 3 3 3 1 AAA+ lid domain AAA PF00004.29 EGB08001.1 - 2.1e-07 31.4 0.0 4.8e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_M50B PF13398.6 EGB08001.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like BAAT_C PF08840.11 EGB08001.1 - 0.17 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal 2OG-FeII_Oxy_3 PF13640.6 EGB08002.1 - 2e-07 31.8 0.0 4.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tim17 PF02466.19 EGB08002.1 - 1.9e-06 28.2 9.0 4.7e-06 27.0 9.0 1.7 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Anoctamin PF04547.12 EGB08003.1 - 3.7e-26 92.0 0.0 4.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 EGB08003.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin G10 PF01125.17 EGB08004.1 - 2.5e-51 173.3 1.2 2.7e-51 173.2 1.2 1.0 1 0 0 1 1 1 1 G10 protein Methyltrans_RNA PF04452.14 EGB08005.1 - 6.6e-39 133.6 0.0 7.6e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase Thioredoxin PF00085.20 EGB08006.1 - 1.2e-16 60.6 0.4 1.5e-16 60.3 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGB08006.1 - 9.6e-06 25.8 0.1 0.19 12.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB08006.1 - 2.1e-05 24.9 0.2 0.00032 21.1 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGB08006.1 - 0.00023 21.3 0.1 0.00049 20.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGB08006.1 - 0.0094 15.9 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGB08006.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 EGB08006.1 - 0.081 13.1 0.2 0.85 9.8 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin OST3_OST6 PF04756.13 EGB08006.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 EGB08006.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 EGB08006.1 - 0.22 11.2 1.7 0.9 9.2 1.0 2.0 1 1 1 2 2 2 0 Redoxin Dus PF01207.17 EGB08007.1 - 1e-32 113.5 0.0 1.1e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Exo_endo_phos PF03372.23 EGB08009.1 - 5.9e-10 39.0 0.0 1.6e-08 34.3 0.0 2.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WW PF00397.26 EGB08009.1 - 0.00013 22.0 2.6 0.00023 21.2 2.6 1.4 1 0 0 1 1 1 1 WW domain ZapD PF07072.11 EGB08009.1 - 0.97 9.1 3.9 3.6 7.3 1.4 2.5 2 0 0 2 2 2 0 Cell division protein ABC1 PF03109.16 EGB08010.1 - 4.7e-22 78.4 0.0 1e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGB08010.1 - 0.18 11.1 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain LRR_6 PF13516.6 EGB08011.1 - 3.4e-07 29.8 5.6 0.0058 16.6 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeat EF-hand_1 PF00036.32 EGB08012.1 - 2.9e-18 64.0 1.2 0.0012 18.3 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB08012.1 - 1.8e-16 60.3 0.1 2.6e-09 37.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB08012.1 - 7.8e-15 53.5 2.0 0.013 15.4 0.1 4.8 5 0 0 5 5 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB08012.1 - 5.2e-10 38.3 2.6 0.028 13.9 0.1 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EGB08012.1 - 1.1e-07 31.6 1.3 0.0095 15.8 0.1 4.3 3 1 1 4 4 4 2 EF-hand domain pair Kelch_2 PF07646.15 EGB08012.1 - 5.6e-06 26.1 1.3 0.28 11.2 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EGB08012.1 - 8.7e-05 22.5 0.7 0.31 11.1 0.1 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EGB08012.1 - 0.00018 21.7 0.1 14 6.2 0.0 5.1 4 1 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 EGB08012.1 - 0.004 16.7 2.3 0.5 10.0 0.0 3.8 4 0 0 4 4 4 1 Kelch motif EF-hand_13 PF17958.1 EGB08012.1 - 0.066 13.0 0.0 11 6.0 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain XPB_DRD PF18458.1 EGB08012.1 - 0.25 11.3 8.7 0.62 10.0 0.7 3.8 3 0 0 3 3 3 0 Xeroderma pigmentosum group B helicase damage recognition domain Kelch_3 PF13415.6 EGB08012.1 - 2.1 8.8 5.8 21 5.6 0.0 3.8 4 0 0 4 4 2 0 Galactose oxidase, central domain Peptidase_S24 PF00717.23 EGB08014.1 - 1.2e-10 41.2 0.4 1.9e-10 40.5 0.4 1.4 1 0 0 1 1 1 1 Peptidase S24-like ArsA_ATPase PF02374.15 EGB08015.1 - 2.5e-67 227.2 0.0 6.1e-37 127.4 0.0 4.2 3 1 0 3 3 3 3 Anion-transporting ATPase CbiA PF01656.23 EGB08015.1 - 2.5e-16 59.9 0.0 2.6e-07 30.7 0.0 3.1 2 2 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGB08015.1 - 3.2e-15 56.5 1.4 4.8e-08 33.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 EGB08015.1 - 1e-09 38.2 4.7 7.2e-05 22.3 0.4 2.3 2 0 0 2 2 2 2 PhoH-like protein ParA PF10609.9 EGB08015.1 - 5e-08 32.7 5.8 0.0015 18.1 0.7 2.8 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 EGB08015.1 - 1.1e-07 31.6 3.6 0.0068 16.0 0.2 3.0 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.18 EGB08015.1 - 2.7e-07 30.3 1.7 0.0021 17.5 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 EGB08015.1 - 1.5e-05 25.4 7.9 0.00018 21.9 0.3 2.9 2 1 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 EGB08015.1 - 1.6e-05 24.0 9.0 0.00031 19.8 1.2 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 EGB08015.1 - 1.7e-05 24.6 3.9 0.016 14.9 0.4 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein APS_kinase PF01583.20 EGB08015.1 - 0.00014 21.8 1.9 0.23 11.4 0.2 2.3 2 0 0 2 2 2 2 Adenylylsulphate kinase NB-ARC PF00931.22 EGB08015.1 - 0.00029 20.1 1.9 0.0072 15.5 0.2 2.1 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 EGB08015.1 - 0.00046 20.1 5.2 0.15 11.9 1.1 2.4 2 0 0 2 2 2 2 NACHT domain MipZ PF09140.11 EGB08015.1 - 0.0012 18.1 1.7 0.53 9.5 0.1 3.1 3 0 0 3 3 3 1 ATPase MipZ AAA PF00004.29 EGB08015.1 - 0.0075 16.7 1.9 0.14 12.6 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGB08015.1 - 0.0084 16.3 0.2 0.14 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EGB08015.1 - 0.0091 15.6 10.5 0.13 11.9 1.4 3.0 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EGB08015.1 - 0.012 15.5 0.1 0.74 9.7 0.0 2.6 3 0 0 3 3 2 0 RsgA GTPase Zeta_toxin PF06414.12 EGB08015.1 - 0.015 14.6 2.2 0.22 10.8 0.2 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EGB08015.1 - 0.015 15.8 1.0 5.1 7.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGB08015.1 - 0.016 15.0 2.4 0.87 9.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGB08015.1 - 0.019 14.7 9.9 0.037 13.7 1.5 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGB08015.1 - 0.033 14.2 3.1 0.19 11.7 0.4 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EGB08015.1 - 0.051 13.3 1.8 1.9 8.3 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain CBP_BcsQ PF06564.12 EGB08015.1 - 0.062 12.8 5.6 1 8.8 0.2 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ NTPase_1 PF03266.15 EGB08015.1 - 0.12 12.3 1.5 2.9 7.8 0.1 2.7 3 0 0 3 3 2 0 NTPase RuvB_N PF05496.12 EGB08015.1 - 0.18 11.5 3.4 1.2 8.9 0.2 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_26 PF13500.6 EGB08015.1 - 0.19 11.5 6.3 1.5 8.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EGB08015.1 - 0.2 11.0 1.0 15 4.9 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EGB08015.1 - 0.34 11.2 1.4 2.7 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGB08015.1 - 0.36 10.3 1.9 6.7 6.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PIF1 PF05970.14 EGB08015.1 - 0.51 9.5 0.9 12 5.0 0.2 2.2 2 0 0 2 2 2 0 PIF1-like helicase ATP_bind_1 PF03029.17 EGB08015.1 - 1.4 8.7 4.6 0.72 9.6 0.5 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TIP49 PF06068.13 EGB08015.1 - 1.8 7.6 2.6 20 4.2 0.3 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_5 PF07728.14 EGB08015.1 - 2 8.4 3.8 9.5 6.2 1.0 2.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) YjeF_N PF03853.15 EGB08015.1 - 4.7 7.1 15.3 0.41 10.5 0.5 3.9 4 1 0 4 4 4 0 YjeF-related protein N-terminus ABC_tran PF00005.27 EGB08015.1 - 4.9 7.7 4.9 3.3 8.2 0.5 2.3 2 0 0 2 2 2 0 ABC transporter SAF PF08666.12 EGB08016.1 - 0.17 12.5 1.7 6.7 7.4 0.8 2.5 2 0 0 2 2 2 0 SAF domain PAP_central PF04928.17 EGB08017.1 - 1.8e-78 263.0 0.0 2.4e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGB08017.1 - 5.5e-08 32.6 0.0 8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGB08017.1 - 1.6e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Brix PF04427.18 EGB08018.1 - 7.1e-18 65.4 0.0 2.2e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Brix domain MPP6 PF10175.9 EGB08018.1 - 0.02 15.4 1.0 0.035 14.6 1.0 1.3 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Amino_oxidase PF01593.24 EGB08019.1 - 3.1e-18 66.3 3.3 5.8e-17 62.1 3.3 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB08019.1 - 1.2e-12 47.8 0.7 1.2e-12 47.8 0.7 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGB08019.1 - 2.5e-09 36.8 4.9 1.4e-05 24.3 0.5 2.6 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 EGB08019.1 - 0.00016 20.5 0.1 0.047 12.4 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EGB08019.1 - 0.00055 20.4 2.6 0.21 12.2 0.8 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB08019.1 - 0.0012 18.2 1.0 0.0019 17.5 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB08019.1 - 0.0015 17.8 4.1 0.021 14.1 0.4 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB08019.1 - 0.0016 18.1 13.7 0.013 15.1 13.7 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGB08019.1 - 0.0058 15.9 0.2 0.01 15.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EGB08019.1 - 0.0073 15.7 0.9 0.0073 15.7 0.9 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 EGB08019.1 - 0.014 13.9 0.0 0.15 10.6 0.1 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor UPF0227 PF05728.12 EGB08019.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pyr_redox_3 PF13738.6 EGB08019.1 - 0.25 10.6 0.4 0.39 9.9 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGB08019.1 - 3.5 7.3 4.8 6.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Peptidase_M16 PF00675.20 EGB08020.1 - 2.8e-47 160.5 0.0 4.2e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGB08020.1 - 2.9e-25 89.3 0.0 5.6e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF1269 PF06897.12 EGB08020.1 - 0.049 13.9 2.6 0.071 13.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Scramblase PF03803.15 EGB08022.1 - 0.033 13.5 0.2 0.21 10.9 0.2 2.0 1 1 0 1 1 1 0 Scramblase IHABP4_N PF16174.5 EGB08022.1 - 0.037 14.6 0.0 0.044 14.4 0.0 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Scramblase PF03803.15 EGB08023.1 - 4.8e-24 84.9 0.0 6.8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Scramblase Ank_2 PF12796.7 EGB08024.1 - 2.5e-16 60.0 0.0 1.6e-08 35.0 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB08024.1 - 8.7e-13 47.2 0.1 0.0004 20.6 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGB08024.1 - 1.9e-10 40.7 3.1 0.0001 22.6 0.4 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGB08024.1 - 3e-10 40.1 3.6 1.4e-08 34.9 0.1 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB08024.1 - 1.3e-09 38.4 1.6 2.1e-06 28.1 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB08025.1 - 5.5e-31 107.0 0.3 5.3e-05 23.7 0.0 8.7 6 2 4 10 10 10 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08025.1 - 2.9e-18 66.0 6.5 0.0021 18.6 0.2 11.1 10 2 2 12 12 12 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB08025.1 - 1.2e-15 57.4 20.2 0.033 14.5 0.1 10.5 8 3 2 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 EGB08025.1 - 1e-14 54.2 25.2 0.056 13.9 0.0 12.1 12 0 0 12 12 12 4 Ankyrin repeat zf-C3HC4_2 PF13923.6 EGB08025.1 - 1.3e-09 37.8 5.5 2.3e-09 36.9 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB08025.1 - 7e-09 35.9 5.1 7e-09 35.9 5.1 1.8 2 0 0 2 2 1 1 Ring finger domain Ank_3 PF13606.6 EGB08025.1 - 8.4e-09 35.0 20.4 19 6.2 0.0 13.2 17 1 0 17 17 13 0 Ankyrin repeat zf-RING_UBOX PF13445.6 EGB08025.1 - 4.3e-08 33.0 0.8 4.3e-08 33.0 0.8 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGB08025.1 - 1.4e-07 31.3 1.7 2.2e-07 30.6 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB08025.1 - 2.5e-07 30.5 2.9 4.3e-07 29.7 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB08025.1 - 3.1e-06 27.4 4.2 7.8e-06 26.1 4.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGB08025.1 - 4.8e-06 26.3 3.8 8.7e-06 25.5 3.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGB08025.1 - 6.5e-05 23.0 4.0 0.00011 22.3 4.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.15 EGB08025.1 - 0.00055 20.1 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 EGB08025.1 - 0.00059 19.7 2.8 0.001 19.0 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 EGB08025.1 - 0.026 14.3 0.6 0.05 13.4 0.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EGB08025.1 - 0.036 13.8 0.7 0.096 12.5 0.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EGB08025.1 - 0.039 14.0 2.3 0.069 13.2 1.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 EGB08025.1 - 0.16 12.1 0.9 0.37 10.9 0.9 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF4239 PF14023.6 EGB08026.1 - 1.6e-11 44.3 0.0 3.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Sulfotransfer_4 PF17784.1 EGB08026.1 - 2.3e-10 40.7 0.4 1.1e-07 31.9 0.4 3.1 1 1 0 1 1 1 1 Sulfotransferase domain YhfT PF10797.9 EGB08026.1 - 0.065 12.3 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function Mannosyl_trans3 PF11051.8 EGB08026.1 - 0.3 10.4 0.0 0.85 8.9 0.0 1.6 2 0 0 2 2 2 0 Mannosyltransferase putative Helicase_C PF00271.31 EGB08027.1 - 9.7e-17 61.3 0.0 6.2e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB08027.1 - 2.6e-16 59.9 0.0 3.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB08027.1 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EGB08028.1 - 8.1e-29 100.9 0.0 1.1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGB08028.1 - 9.6e-07 28.5 0.0 1.8e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB08028.1 - 1.2e-05 25.7 0.3 2.3e-05 24.9 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB08028.1 - 0.00025 21.0 0.1 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGB08028.1 - 0.00031 20.5 2.9 0.0029 17.4 2.9 2.1 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EGB08028.1 - 0.0094 16.0 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EGB08028.1 - 0.019 14.9 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 EGB08028.1 - 0.027 14.7 0.4 0.44 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB08028.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EGB08028.1 - 0.034 13.9 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EGB08028.1 - 0.065 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGB08028.1 - 0.076 13.0 0.1 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EGB08028.1 - 0.092 12.5 0.6 0.14 11.9 0.2 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EGB08028.1 - 0.11 13.1 0.2 0.22 12.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB08028.1 - 0.16 11.9 0.0 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 EGB08028.1 - 0.17 12.3 0.0 13 6.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4336 PF14234.6 EGB08029.1 - 8.4e-120 399.8 0.0 9.4e-120 399.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) Methyltransf_21 PF05050.12 EGB08030.1 - 3.6e-05 23.9 0.0 0.00014 22.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF938 PF06080.12 EGB08030.1 - 0.00038 20.3 0.0 0.00058 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 EGB08030.1 - 0.00083 20.0 0.0 0.0021 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB08030.1 - 0.0012 19.6 0.0 0.004 17.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain GidB PF02527.15 EGB08030.1 - 0.003 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 EGB08030.1 - 0.0048 16.4 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 EGB08031.1 - 4.6e-72 242.1 0.0 5.2e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGB08031.1 - 2.2e-16 60.3 0.0 5.7e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB08031.1 - 1.9e-15 57.3 0.0 4.8e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB08031.1 - 5.9e-13 48.9 0.0 8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB08031.1 - 4e-11 43.5 0.0 7.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB08031.1 - 3.9e-10 39.8 0.0 5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGB08031.1 - 0.0028 17.6 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EGB08031.1 - 0.0039 15.8 0.0 0.0052 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_S25 PF03297.15 EGB08032.1 - 3.6e-43 145.9 4.8 4e-43 145.7 4.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 EGB08032.1 - 7.4e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 EGB08032.1 - 0.0073 16.5 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EGB08032.1 - 0.0073 15.8 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EGB08032.1 - 0.016 15.1 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 MarR family GntR PF00392.21 EGB08032.1 - 0.06 13.0 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MerR_2 PF13591.6 EGB08032.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.6 1 1 1 2 2 2 0 MerR HTH family regulatory protein Chloroa_b-bind PF00504.21 EGB08033.1 - 7.2e-31 107.9 0.1 1e-30 107.4 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4953 PF16313.5 EGB08034.1 - 1.4e-62 211.8 0.2 1.9e-62 211.3 0.2 1.2 1 0 0 1 1 1 1 Met-zincin DUF5117 PF17148.4 EGB08034.1 - 1e-07 32.0 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5117) Reprolysin_2 PF13574.6 EGB08034.1 - 0.00013 22.0 0.1 0.00022 21.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EGB08034.1 - 0.00035 20.3 0.7 0.00063 19.4 0.7 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EGB08034.1 - 0.00047 20.4 0.9 0.00088 19.5 0.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 EGB08034.1 - 0.0013 18.6 1.7 0.003 17.4 1.7 1.5 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 EGB08034.1 - 0.0014 19.2 0.1 0.0027 18.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EGB08034.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 EGB08034.1 - 0.13 11.2 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 EGB08034.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Glyco_hydro_28 PF00295.17 EGB08035.1 - 2.8e-47 161.4 0.1 3.9e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MFS_1 PF07690.16 EGB08035.1 - 9.5e-31 107.0 22.0 1.3e-30 106.5 22.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pectate_lyase_3 PF12708.7 EGB08035.1 - 9.6e-12 45.2 5.4 2.8e-11 43.7 5.4 1.8 1 1 0 1 1 1 1 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGB08035.1 - 0.0042 16.7 0.3 0.012 15.3 0.3 1.8 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase OATP PF03137.20 EGB08035.1 - 0.0097 14.2 0.1 0.0097 14.2 0.1 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Pro_isomerase PF00160.21 EGB08036.1 - 4.9e-43 147.1 0.1 5.6e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.23 EGB08038.1 - 3.4e-137 446.4 19.2 1.1e-33 114.8 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EGB08038.1 - 2.5e-64 213.0 22.3 1.4e-15 56.9 0.8 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB08038.1 - 7e-26 90.5 8.8 0.0001 22.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB08038.1 - 8.2e-18 64.1 3.5 0.012 15.6 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB08038.1 - 3.8e-16 59.2 2.1 0.051 13.7 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGB08038.1 - 6.6e-15 55.3 5.8 0.048 14.0 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 EGB08038.1 - 2e-14 54.0 0.7 0.17 12.5 0.0 4.2 1 1 0 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGB08038.1 - 5.6e-08 32.8 0.0 3.8 7.3 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EGB08038.1 - 2.3e-06 27.6 22.0 25 5.0 0.0 7.9 8 0 0 8 8 8 0 Ubiquitin-like domain TmoB PF06234.12 EGB08038.1 - 3.7e-06 26.9 0.1 22 5.2 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) DUF2870 PF11069.8 EGB08038.1 - 8.5e-06 26.1 0.0 30 5.1 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 EGB08038.1 - 0.0001 22.4 1.2 12 6.1 0.0 3.9 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase Raf1_HTH PF18579.1 EGB08038.1 - 0.00021 20.9 1.4 37 4.1 0.0 4.2 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain DUF969 PF06149.12 EGB08038.1 - 0.0005 19.6 0.0 25 4.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) DUF1940 PF09155.10 EGB08038.1 - 0.0021 18.2 6.2 31 4.6 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1940) DUF3861 PF12977.7 EGB08038.1 - 0.0033 17.6 1.9 79 3.5 0.0 4.1 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) ORF11CD3 PF10549.9 EGB08038.1 - 0.0033 17.5 0.0 91 3.3 0.0 4.8 4 0 0 4 4 4 0 ORF11CD3 domain CorA PF01544.18 EGB08038.1 - 0.0075 15.6 0.3 70 2.6 0.0 3.9 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein ProRS-C_2 PF09181.10 EGB08038.1 - 0.032 14.4 2.1 1.5e+02 2.6 0.0 4.0 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal TraK PF06586.11 EGB08038.1 - 0.051 13.3 0.4 1.4e+02 2.0 0.0 3.9 4 0 0 4 4 4 0 TraK protein Baculo_p48 PF04878.13 EGB08038.1 - 0.068 12.1 0.0 50 2.7 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Big_7 PF17957.1 EGB08038.1 - 0.069 13.9 0.0 3.7e+02 2.0 0.0 3.9 4 0 0 4 4 4 0 Bacterial Ig domain Myosin_N PF02736.19 EGB08038.1 - 0.16 11.8 7.9 62 3.5 0.1 5.0 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 EGB08038.1 - 0.25 11.1 7.2 81 3.1 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain DMA PF03474.14 EGB08038.1 - 0.29 10.8 4.0 1e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 DMRTA motif FlgD_ig PF13860.6 EGB08038.1 - 0.46 10.4 6.3 1.3e+02 2.5 0.1 4.2 4 0 0 4 4 4 0 FlgD Ig-like domain HAMP_N3 PF18575.1 EGB08038.1 - 1.8 8.2 3.5 2.4e+02 1.4 0.0 3.8 4 0 0 4 4 4 0 HAMP N-terminal domain 3 DnaJ PF00226.31 EGB08039.1 - 1.3e-19 70.0 0.2 1.7e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain Zeta_toxin PF06414.12 EGB08040.1 - 5.6e-19 68.2 0.0 9.6e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EGB08040.1 - 1.4e-09 38.2 0.1 3e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain GST_N_2 PF13409.6 EGB08041.1 - 9.1e-06 25.9 0.1 1.9e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB08041.1 - 1.4e-05 25.4 0.0 3.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PARP PF00644.20 EGB08041.1 - 6.9e-05 22.5 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain GST_C_2 PF13410.6 EGB08041.1 - 0.035 14.1 0.3 0.31 11.1 0.3 2.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Toxin_24 PF08094.11 EGB08041.1 - 0.65 9.9 5.1 0.26 11.1 1.3 2.3 2 0 0 2 2 2 0 Conotoxin TVIIA/GS family Ephrin_rec_like PF07699.13 EGB08042.1 - 1.7e-12 46.9 53.7 1e-05 25.2 2.0 7.1 1 1 9 10 10 10 10 Putative ephrin-receptor like NCD3G PF07562.14 EGB08042.1 - 1.4e-10 41.0 38.0 0.013 15.5 1.0 6.7 2 2 5 8 8 8 8 Nine Cysteines Domain of family 3 GPCR zf-RRN7 PF11781.8 EGB08042.1 - 0.19 11.5 0.5 0.19 11.5 0.5 6.6 7 0 0 7 7 7 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 VSP PF03302.13 EGB08042.1 - 5.1 5.9 66.7 0.31 9.8 27.3 3.3 1 1 2 3 3 3 0 Giardia variant-specific surface protein Sel1 PF08238.12 EGB08043.1 - 2.3e-22 78.9 9.6 9.7e-09 35.6 0.0 3.0 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.6 EGB08043.1 - 0.092 13.4 4.9 50 4.8 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 EGB08044.1 - 8.7e-10 39.1 0.4 1.3e-09 38.6 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB08044.1 - 1.4e-07 32.2 0.4 2.2e-07 31.5 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB08044.1 - 7.3e-06 25.8 0.1 9.5e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB08044.1 - 0.039 13.5 0.3 0.07 12.7 0.3 1.4 1 1 0 1 1 1 0 Methyltransferase small domain PGM_PMM_I PF02878.16 EGB08044.1 - 0.061 13.0 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Lipase_GDSL_2 PF13472.6 EGB08045.1 - 1.7e-08 35.1 0.8 4.3e-08 33.7 0.8 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glucan_synthase PF02364.15 EGB08046.1 - 7.5e-201 669.4 0.0 3.8e-198 660.5 0.0 2.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EGB08046.1 - 7.3e-22 78.1 0.0 2.2e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF2052 PF09747.9 EGB08048.1 - 1.6e-05 25.1 14.0 0.00016 21.9 0.1 2.3 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) zf-RanBP PF00641.18 EGB08048.1 - 0.058 12.7 2.1 0.1 12.0 2.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-P11 PF03854.14 EGB08048.1 - 0.1 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 P-11 zinc finger PNISR PF15996.5 EGB08048.1 - 0.2 11.9 15.3 1.1 9.5 6.4 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR SDA1 PF05285.12 EGB08048.1 - 0.21 11.0 25.9 0.16 11.3 1.2 2.1 2 0 0 2 2 2 0 SDA1 SpoIIIAH PF12685.7 EGB08048.1 - 0.21 11.4 12.4 0.95 9.3 6.9 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Nop14 PF04147.12 EGB08048.1 - 0.23 9.6 29.5 0.19 9.9 7.3 2.0 2 0 0 2 2 2 0 Nop14-like family Mpp10 PF04006.12 EGB08048.1 - 0.61 8.5 20.9 0.65 8.4 2.0 2.0 2 0 0 2 2 2 0 Mpp10 protein DUF2151 PF10221.9 EGB08048.1 - 0.69 8.4 6.2 0.35 9.4 0.1 2.0 2 0 0 2 2 2 0 Cell cycle and development regulator RNA_pol_3_Rpc31 PF11705.8 EGB08048.1 - 0.73 10.1 22.1 1 9.6 4.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SAPS PF04499.15 EGB08048.1 - 0.76 8.5 13.7 0.23 10.2 5.4 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 EGB08048.1 - 0.97 7.6 19.3 0.24 9.7 0.9 2.1 2 0 0 2 2 2 0 CDC45-like protein Sporozoite_P67 PF05642.11 EGB08048.1 - 4.4 5.3 15.5 0.29 9.2 1.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 EGB08048.1 - 4.5 6.9 28.2 0.045 13.5 5.9 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Tim54 PF11711.8 EGB08048.1 - 6.4 5.5 13.4 0.74 8.5 2.5 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 EGB08048.1 - 7.3 5.5 13.4 2.4 7.0 1.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) 60KD_IMP PF02096.20 EGB08049.1 - 7.2e-54 182.1 1.6 8.1e-54 182.0 1.6 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein Ank_2 PF12796.7 EGB08050.1 - 1.3e-24 86.6 2.4 6e-14 52.4 0.2 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08050.1 - 4.4e-22 78.2 10.6 5.4e-06 26.8 0.1 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB08050.1 - 4.9e-21 74.5 13.8 1.5e-09 37.9 0.7 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08050.1 - 1.6e-18 64.9 4.7 0.00034 20.8 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EGB08050.1 - 3e-14 52.7 11.4 1.9e-05 24.9 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat BPL_N PF09825.9 EGB08050.1 - 0.012 14.8 4.9 0.21 10.6 0.6 2.3 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal NHL PF01436.21 EGB08051.1 - 0.00038 20.3 0.3 0.22 11.6 0.0 3.5 4 0 0 4 4 4 2 NHL repeat DNA_topoisoIV PF00521.20 EGB08052.1 - 3.3e-121 405.2 0.0 5.1e-121 404.5 0.0 1.3 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 EGB08052.1 - 1.3e-51 171.9 13.5 8.5e-12 44.4 0.2 6.7 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller JAB PF01398.21 EGB08053.1 - 5.9e-17 61.7 0.1 9.8e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGB08053.1 - 0.0052 16.6 0.1 0.012 15.4 0.1 1.7 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Mtc PF03820.17 EGB08054.1 - 7.5e-79 265.0 0.0 8.4e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier cobW PF02492.19 EGB08056.1 - 5.2e-38 130.4 0.1 6.8e-38 130.0 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB08056.1 - 9.7e-22 76.7 0.0 2e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGB08056.1 - 0.00042 20.2 0.5 0.36 10.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB08056.1 - 0.0035 17.8 2.4 0.019 15.4 2.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 EGB08056.1 - 0.0094 15.9 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 EGB08056.1 - 0.043 13.7 0.1 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EGB08056.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGB08056.1 - 0.14 12.4 0.2 0.68 10.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EGB08056.1 - 0.19 10.7 1.6 8.3 5.3 0.1 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EGB08056.1 - 0.21 11.7 0.4 3.5 7.8 0.4 2.3 1 1 0 1 1 1 0 AAA domain Nodulin-like PF06813.13 EGB08057.1 - 6.4e-30 104.5 5.2 6.4e-30 104.5 5.2 1.7 2 0 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 EGB08057.1 - 6e-14 51.7 61.8 3.7e-11 42.5 48.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycos_transf_2 PF00535.26 EGB08058.1 - 1e-11 44.9 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB08058.1 - 1.2e-08 35.2 0.0 2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGB08058.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EGB08058.1 - 0.049 13.1 0.0 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Metallophos PF00149.28 EGB08059.1 - 1e-28 101.2 0.2 1.3e-28 100.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GXGXG PF01493.19 EGB08059.1 - 0.045 13.3 0.1 0.074 12.6 0.1 1.3 1 0 0 1 1 1 0 GXGXG motif Metallothio_Euk PF12749.7 EGB08060.1 - 0.13 12.4 93.4 1.7 8.8 26.3 4.1 1 1 2 3 3 3 0 Eukaryotic metallothionein Metallothio_PEC PF02068.16 EGB08060.1 - 0.24 11.8 86.9 0.59 10.5 28.3 3.5 1 1 2 3 3 3 0 Plant PEC family metallothionein Oxidored_molyb PF00174.19 EGB08061.1 - 5.6e-35 120.5 0.0 8.5e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGB08061.1 - 1.2e-16 61.0 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EGB08061.1 - 1.1e-11 44.7 0.1 3.6e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 EGB08061.1 - 0.036 14.0 0.3 0.17 12.0 0.3 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat HECT PF00632.25 EGB08062.1 - 3.7e-81 273.0 0.0 4.4e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glyco_transf_8 PF01501.20 EGB08063.1 - 4e-05 23.3 0.0 6.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 2OG-FeII_Oxy_3 PF13640.6 EGB08063.1 - 0.0012 19.7 0.0 0.018 15.9 0.0 2.7 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.11 EGB08063.1 - 0.0088 15.7 0.2 0.13 12.0 0.0 2.6 3 0 0 3 3 3 1 Cupin domain PhyH PF05721.13 EGB08063.1 - 0.23 11.7 9.1 21 5.3 0.0 5.5 5 0 0 5 5 5 0 Phytanoyl-CoA dioxygenase (PhyH) PT PF04886.12 EGB08064.1 - 0.00038 19.9 39.1 0.0016 17.9 17.7 5.4 3 1 1 4 4 4 2 PT repeat Mcl1_mid PF12341.8 EGB08065.1 - 4.1e-60 203.6 0.0 5.9e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region SPT6_acidic PF14632.6 EGB08065.1 - 1.6 9.4 12.9 3.2 8.4 12.9 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Thioredoxin PF00085.20 EGB08067.1 - 9.9e-06 25.5 0.5 1.9e-05 24.6 0.5 1.4 1 1 0 1 1 1 1 Thioredoxin Castor_Poll_mid PF06241.12 EGB08068.1 - 3.1e-29 101.0 0.0 4.9e-27 93.9 0.0 3.4 4 0 0 4 4 4 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 EGB08068.1 - 0.00019 21.2 0.1 0.0021 17.9 0.0 2.8 3 0 0 3 3 3 1 TrkA-C domain TrkA_N PF02254.18 EGB08068.1 - 0.0048 17.1 0.8 0.41 10.9 0.2 2.8 2 0 0 2 2 2 2 TrkA-N domain HSF_DNA-bind PF00447.17 EGB08069.1 - 1.2e-20 73.9 0.0 1.5e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding ABC2_membrane PF01061.24 EGB08070.1 - 2.5e-26 92.4 9.5 3.4e-26 92.0 9.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGB08070.1 - 4.4e-23 82.3 0.0 5.9e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB08070.1 - 1.7e-05 25.2 3.5 3.6e-05 24.2 3.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB08070.1 - 5.6e-05 23.1 0.0 0.007 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB08070.1 - 0.00014 21.5 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EGB08070.1 - 0.00029 20.1 2.5 0.00041 19.6 2.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGB08070.1 - 0.0068 16.3 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EGB08070.1 - 0.0086 15.5 0.2 0.1 12.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGB08070.1 - 0.013 16.0 0.1 0.019 15.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGB08070.1 - 0.016 15.7 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGB08070.1 - 0.017 14.7 1.0 0.067 12.8 0.8 2.0 1 1 1 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EGB08070.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 EGB08070.1 - 0.027 14.7 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB08070.1 - 0.047 13.4 0.6 0.13 11.9 0.6 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB08070.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 EGB08070.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGB08070.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB08070.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGB08070.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 EGB08070.1 - 0.24 11.2 0.1 0.39 10.5 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.21 EGB08071.1 - 2.8e-45 153.9 0.0 3e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGB08071.1 - 1.8e-12 47.5 0.0 2.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGB08071.1 - 3.8e-11 42.9 0.0 5.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGB08071.1 - 9.6e-10 38.6 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGB08071.1 - 3e-07 29.9 0.2 0.00043 19.5 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGB08071.1 - 3.2e-07 29.9 0.0 3.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGB08071.1 - 3.8e-07 29.8 0.0 1.9e-05 24.3 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGB08071.1 - 4.2e-06 26.3 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 EGB08071.1 - 0.0002 21.0 0.1 0.1 12.2 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 EGB08071.1 - 0.0033 16.9 1.7 0.053 13.1 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGB08071.1 - 0.0082 16.2 0.1 1.7 8.7 0.1 2.1 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EGB08071.1 - 0.016 15.1 0.1 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TIR_2 PF13676.6 EGB08071.1 - 0.052 14.2 0.0 0.075 13.6 0.0 1.2 1 0 0 1 1 1 0 TIR domain MMR_HSR1_Xtn PF16897.5 EGB08071.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain NTPase_1 PF03266.15 EGB08071.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 NTPase Pkinase PF00069.25 EGB08072.1 - 5.2e-47 160.4 0.0 6.6e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08072.1 - 1.3e-27 96.7 0.0 1.8e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB08072.1 - 1.1e-07 31.5 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB08072.1 - 1.7e-07 31.4 0.1 0.0025 17.8 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB08072.1 - 0.00059 18.9 0.0 0.00096 18.2 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB08072.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Epimerase PF01370.21 EGB08073.1 - 9e-55 185.7 0.0 1.1e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB08073.1 - 9e-18 64.7 0.3 2.4e-17 63.3 0.0 1.6 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGB08073.1 - 1.5e-06 27.6 1.8 2e-05 23.9 0.1 2.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGB08073.1 - 7.9e-06 25.2 0.0 2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGB08073.1 - 0.011 14.9 0.4 0.034 13.3 0.0 1.8 1 1 1 2 2 2 0 Male sterility protein Glyco_hydro_3_C PF01915.22 EGB08074.1 - 5e-48 163.8 0.0 7e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGB08074.1 - 7.3e-47 160.3 0.0 1.1e-46 159.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGB08074.1 - 1.6e-17 63.4 0.0 3.6e-17 62.2 0.0 1.7 1 1 0 1 1 1 1 Fibronectin type III-like domain Vault_3 PF17795.1 EGB08075.1 - 3.4e-09 36.6 0.0 0.14 12.2 0.0 4.7 4 0 0 4 4 4 3 Major Vault Protein Repeat domain Vault_4 PF17796.1 EGB08075.1 - 2.9e-06 27.2 0.5 0.021 14.9 0.0 5.1 5 0 0 5 5 5 1 Major Vault Protein repeat domain Band_7 PF01145.25 EGB08075.1 - 4.4e-06 26.8 0.0 4.4e-06 26.8 0.0 3.0 2 0 0 2 2 2 1 SPFH domain / Band 7 family DUF1664 PF07889.12 EGB08075.1 - 0.49 10.4 3.7 4 7.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lig_chan PF00060.26 EGB08076.1 - 2.3e-08 34.0 0.6 3.8e-08 33.3 0.6 1.4 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 EGB08076.1 - 7.5e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 DUF5493 PF17597.2 EGB08076.1 - 1.2 9.4 4.4 0.29 11.4 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5493) Abhydrolase_1 PF00561.20 EGB08077.1 - 0.013 15.1 0.8 0.028 14.1 0.8 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB08077.1 - 0.015 14.6 0.0 6.9 5.9 0.0 3.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 tRNA_U5-meth_tr PF05958.11 EGB08078.1 - 2.7e-43 148.3 0.0 4.2e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Pkinase PF00069.25 EGB08078.1 - 4.1e-33 114.9 0.0 6.8e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08078.1 - 4.8e-15 55.5 0.0 7.8e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_25 PF13649.6 EGB08078.1 - 9.2e-05 23.1 0.1 0.0061 17.2 0.1 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGB08078.1 - 0.0022 17.6 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EGB08078.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PCMT PF01135.19 EGB08078.1 - 0.02 14.7 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 EGB08078.1 - 0.068 12.2 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 EGB08078.1 - 0.093 13.4 0.2 1 10.0 0.1 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 EGB08078.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 EGB08078.1 - 0.14 11.7 0.1 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Aldo_ket_red PF00248.21 EGB08080.1 - 3.8e-45 154.3 0.0 6.3e-45 153.6 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Prominin PF05478.11 EGB08081.1 - 0.16 9.9 4.4 0.34 8.8 4.4 1.5 1 0 0 1 1 1 0 Prominin HNF_C PF09354.10 EGB08082.1 - 0.18 12.9 0.0 0.57 11.3 0.0 1.8 1 0 0 1 1 1 0 HNF3 C-terminal domain Acyl-CoA_dh_C PF12806.7 EGB08083.1 - 6e-24 84.6 0.3 2.2e-23 82.7 0.3 2.0 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 EGB08083.1 - 1.5e-20 73.9 0.7 7.1e-19 68.5 0.7 3.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGB08083.1 - 8e-18 64.4 0.0 3.3e-17 62.5 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGB08083.1 - 7e-17 62.1 0.2 3.3e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 EGB08083.1 - 0.0001 22.3 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal HA PF03457.14 EGB08084.1 - 4.4e-30 103.8 2.3 1.8e-13 50.6 0.2 3.8 3 0 0 3 3 3 3 Helicase associated domain Sulfotransfer_3 PF13469.6 EGB08084.1 - 1.9e-09 38.3 0.1 7.5e-08 33.0 0.0 3.0 2 1 0 2 2 2 1 Sulfotransferase family Lectin_C PF00059.21 EGB08084.1 - 0.0005 20.8 8.7 0.023 15.4 6.2 3.1 2 1 0 2 2 2 1 Lectin C-type domain Sulfotransfer_1 PF00685.27 EGB08084.1 - 0.0035 16.8 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase domain ETF_QO PF05187.13 EGB08085.1 - 0.026 14.6 0.1 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S CTP_synth_N PF06418.14 EGB08086.1 - 5.5e-117 389.8 0.0 7.2e-117 389.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGB08086.1 - 1.4e-52 178.3 0.0 2.2e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGB08086.1 - 7.6e-06 25.8 0.0 2.6e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 EGB08086.1 - 0.023 14.7 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGB08086.1 - 0.2 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 EGB08087.1 - 3.8e-72 243.5 0.0 4.3e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SHOCT PF09851.9 EGB08088.1 - 0.00044 19.9 5.1 0.17 11.7 0.7 2.8 2 0 0 2 2 2 2 Short C-terminal domain Exo_endo_phos PF03372.23 EGB08089.1 - 2.7e-11 43.4 0.1 7.8e-11 41.9 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EGB08089.1 - 2.3e-10 40.5 7.4 0.00074 19.9 0.4 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB08089.1 - 9.6e-07 28.5 5.7 0.00027 20.7 0.2 3.3 1 1 4 5 5 5 4 Leucine rich repeat TPR_9 PF13371.6 EGB08089.1 - 0.00067 19.8 8.0 0.0023 18.1 8.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 EGB08089.1 - 0.0037 18.1 0.0 0.0087 16.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YL1 PF05764.13 EGB08089.1 - 0.21 11.7 5.2 0.36 10.9 5.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein TPR_14 PF13428.6 EGB08089.1 - 5.3 8.1 18.9 4.6 8.3 5.4 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Beta_helix PF13229.6 EGB08090.1 - 5.4e-08 32.8 0.0 0.7 9.7 0.0 4.7 4 1 0 4 4 4 4 Right handed beta helix region 2OG-FeII_Oxy_3 PF13640.6 EGB08091.1 - 3.4e-18 66.3 0.0 6.1e-18 65.5 0.0 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB08091.1 - 0.016 15.8 0.0 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EGB08091.1 - 0.037 13.1 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein CDKN3 PF05706.12 EGB08092.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EGB08092.1 - 0.2 11.2 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase EF-hand_1 PF00036.32 EGB08093.1 - 3.9e-06 26.0 0.0 0.093 12.3 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB08093.1 - 6.6e-06 26.5 0.0 4.9e-05 23.7 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB08093.1 - 1.2e-05 24.8 0.1 0.62 10.2 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EGB08093.1 - 7.8e-05 22.0 0.1 0.23 11.0 0.1 2.8 2 0 0 2 2 2 2 EF hand Peptidase_C92 PF05708.12 EGB08093.1 - 0.00038 20.6 0.0 0.018 15.2 0.0 2.7 2 1 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Aminotran_1_2 PF00155.21 EGB08094.1 - 1.4e-55 189.0 0.0 1.6e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGB08094.1 - 0.00045 19.1 0.2 0.00083 18.2 0.2 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 EGB08094.1 - 0.00051 19.1 0.0 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGB08094.1 - 0.00058 18.5 0.0 0.00085 18.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme EF-hand_8 PF13833.6 EGB08095.1 - 2.6e-13 49.6 1.4 4.4e-08 32.8 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EGB08095.1 - 6.5e-10 39.3 2.0 1.3e-06 28.7 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB08095.1 - 2.4e-07 29.8 4.3 0.31 10.7 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB08095.1 - 5.4e-05 22.8 0.6 0.14 12.2 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 EGB08095.1 - 0.013 15.8 0.1 3 8.2 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 EGB08095.1 - 0.017 14.6 0.4 1.5 8.4 0.1 2.8 2 0 0 2 2 2 0 EF hand K-box PF01486.17 EGB08095.1 - 0.08 13.1 3.5 0.18 12.0 0.8 2.7 3 0 0 3 3 3 0 K-box region DUF4287 PF14117.6 EGB08095.1 - 0.13 12.5 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) DUF4315 PF14193.6 EGB08095.1 - 0.16 12.0 2.3 1.1 9.3 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) S6OS1 PF15676.5 EGB08095.1 - 0.23 9.9 0.2 0.31 9.5 0.2 1.2 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Aldo_ket_red PF00248.21 EGB08097.1 - 3e-62 210.5 0.0 4e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family She9_MDM33 PF05546.11 EGB08098.1 - 7.1e-31 107.6 0.4 1e-30 107.0 0.4 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family Pkinase PF00069.25 EGB08100.1 - 1.1e-55 188.8 0.0 1.3e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08100.1 - 2.1e-37 128.8 0.0 2.3e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB08100.1 - 2.2e-05 23.9 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB08100.1 - 0.035 14.0 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ammonium_transp PF00909.21 EGB08101.1 - 3.1e-91 306.0 26.1 3.8e-91 305.7 26.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RNA_pol_L_2 PF13656.6 EGB08102.1 - 1.8e-25 88.5 0.0 2.3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGB08102.1 - 2.7e-07 29.9 0.0 4.4e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 EGB08103.1 - 5e-33 114.6 0.0 2.4e-26 92.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08103.1 - 2.5e-12 46.6 0.0 4.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB08103.1 - 0.0068 16.4 0.4 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB08103.1 - 0.042 13.1 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Dimerisation PF08100.11 EGB08103.1 - 0.087 12.9 0.3 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Dimerisation domain ShK PF01549.24 EGB08104.1 - 6.8e-15 55.3 23.0 2.5e-07 31.1 8.8 2.7 2 0 0 2 2 2 2 ShK domain-like 2OG-FeII_Oxy_3 PF13640.6 EGB08104.1 - 1.2e-13 51.8 0.0 2.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BLI1 PF17324.2 EGB08105.1 - 0.014 16.0 8.0 4.9 7.9 0.2 3.7 4 0 0 4 4 4 0 BLOC-1 interactor 1 Hamartin PF04388.12 EGB08105.1 - 1.5 7.4 8.9 2.2 6.9 8.9 1.2 1 0 0 1 1 1 0 Hamartin protein CT_C_D PF02682.16 EGB08106.1 - 6.4 6.5 7.7 0.25 11.0 0.4 2.4 2 1 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Lipase_GDSL_2 PF13472.6 EGB08107.1 - 7.5e-06 26.5 0.9 8.8e-05 23.0 0.4 2.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF4752 PF15944.5 EGB08108.1 - 0.13 12.4 2.3 0.22 11.6 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) RseC_MucC PF04246.12 EGB08108.1 - 1 9.3 4.8 3.5 7.6 0.0 2.6 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Slu7 PF11708.8 EGB08109.1 - 1e-83 281.2 19.9 1e-83 281.2 19.9 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor OCRE PF17780.1 EGB08109.1 - 0.41 10.7 3.4 2.5 8.2 0.6 2.9 3 0 0 3 3 3 0 OCRE domain TPR_1 PF00515.28 EGB08110.1 - 3.8e-06 26.5 0.0 8.2e-05 22.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB08110.1 - 2.1e-05 24.3 0.0 0.00044 20.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB08110.1 - 0.0017 18.4 0.0 0.013 15.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGB08110.1 - 0.035 14.1 0.0 1.4 9.1 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB08110.1 - 0.047 14.3 0.0 0.74 10.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HOOK PF05622.12 EGB08111.1 - 1.8e-09 36.4 28.8 1.8e-09 36.4 28.8 3.8 3 1 0 3 3 3 1 HOOK protein TPR_7 PF13176.6 EGB08112.1 - 0.0041 17.0 0.4 7 6.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB08112.1 - 0.0062 16.8 4.1 0.0062 16.8 4.1 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB08112.1 - 0.051 13.5 7.3 0.094 12.6 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB08112.1 - 0.55 10.5 12.0 1.5 9.2 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-MYND PF01753.18 EGB08113.1 - 2.1e-07 30.9 7.2 9.1e-07 28.9 7.2 2.1 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 EGB08113.1 - 1.1e-05 25.9 0.6 0.004 17.7 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB08113.1 - 4.9e-05 23.5 5.1 0.00053 20.2 0.5 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB08113.1 - 0.00015 22.2 0.7 0.35 11.5 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Bot1p PF12298.8 EGB08113.1 - 0.029 14.6 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein Ank PF00023.30 EGB08113.1 - 0.77 10.3 5.8 0.9 10.1 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Epimerase PF01370.21 EGB08114.1 - 7.6e-19 68.1 0.0 9.7e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB08114.1 - 1.6e-13 50.3 0.0 2.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGB08114.1 - 6.2e-13 48.8 0.0 1.7e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGB08114.1 - 1.8e-12 46.9 0.0 2.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGB08114.1 - 1.1e-09 37.9 0.0 1.9e-05 23.9 0.0 2.9 1 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 EGB08114.1 - 0.018 14.5 0.2 0.027 13.9 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 EGB08114.1 - 0.025 14.5 0.1 0.036 14.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 EGB08114.1 - 0.037 13.9 0.7 0.24 11.3 0.8 2.1 1 1 1 2 2 2 0 KR domain Ldh_1_N PF00056.23 EGB08114.1 - 0.16 12.1 0.2 0.24 11.5 0.2 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain HEAT_2 PF13646.6 EGB08115.1 - 3.1e-17 62.7 120.0 5.8e-07 29.8 10.2 11.7 8 4 4 13 13 13 9 HEAT repeats HEAT PF02985.22 EGB08115.1 - 1.1e-05 25.3 63.6 0.24 11.7 0.0 14.8 16 0 0 16 16 16 5 HEAT repeat PH_3 PF14593.6 EGB08115.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PH domain HTH_20 PF12840.7 EGB08115.1 - 0.00017 21.6 5.3 0.27 11.3 0.7 3.9 2 0 0 2 2 2 2 Helix-turn-helix domain Cnd1 PF12717.7 EGB08115.1 - 0.0034 17.4 1.9 0.88 9.6 0.0 4.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IQ PF00612.27 EGB08115.1 - 0.14 12.1 5.1 0.83 9.6 1.3 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif VCBS PF13517.6 EGB08116.1 - 1.8e-58 195.0 108.0 2.8e-10 40.6 5.0 11.2 3 2 6 11 11 11 11 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TRM13 PF05206.14 EGB08116.1 - 7.6e-45 153.5 0.0 1.1e-44 152.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 RGS PF00615.19 EGB08116.1 - 8.8e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain zf-TRM13_CCCH PF11722.8 EGB08116.1 - 1.6e-07 31.0 1.9 4.5e-07 29.5 1.9 1.9 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 EGB08116.1 - 4.4e-07 29.7 0.0 7.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 EGB08116.1 - 0.032 14.2 0.7 0.16 12.0 0.7 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGB08116.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FG-GAP PF01839.23 EGB08116.1 - 0.44 10.7 138.7 0.13 12.5 4.4 14.9 14 0 0 14 14 14 0 FG-GAP repeat EF-hand_1 PF00036.32 EGB08117.1 - 1.7e-14 52.2 0.6 6.8e-06 25.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB08117.1 - 1.4e-13 49.6 2.4 7.7e-07 28.3 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB08117.1 - 1.1e-12 46.8 0.3 6.3e-05 22.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB08117.1 - 1.3e-09 38.4 4.4 2.4e-07 31.1 1.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB08117.1 - 4.2e-08 32.9 0.9 0.0047 16.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB08117.1 - 0.003 17.8 0.1 0.017 15.4 0.1 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region APG6_N PF17675.1 EGB08117.1 - 0.11 13.0 3.4 0.15 12.5 3.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Herpes_UL25 PF01499.16 EGB08117.1 - 1.1 7.7 4.4 1.5 7.3 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF724 PF05266.14 EGB08117.1 - 2.3 8.0 5.5 3 7.6 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) GARS_A PF01071.19 EGB08118.1 - 1.2e-69 234.0 0.0 1.9e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 EGB08118.1 - 2.4e-37 128.4 0.0 4.5e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 EGB08118.1 - 6.4e-30 103.8 3.5 1.9e-29 102.3 1.5 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EGB08118.1 - 1.1e-23 84.1 3.4 2.6e-23 82.9 0.3 3.2 3 0 0 3 3 3 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EGB08118.1 - 2.5e-23 82.1 3.2 2.5e-23 82.1 3.2 3.4 3 1 0 3 3 3 2 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGB08118.1 - 1e-12 48.5 3.9 1e-12 48.5 3.9 3.3 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 EGB08118.1 - 0.018 14.5 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain SAM_2 PF07647.17 EGB08119.1 - 1.1e-13 51.0 0.0 2.9e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGB08119.1 - 2.1e-10 40.8 0.1 4.3e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Pkinase PF00069.25 EGB08120.1 - 1.1e-73 247.8 0.0 1.3e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08120.1 - 2.2e-32 112.4 0.0 2.7e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB08120.1 - 0.00055 19.3 0.1 0.0089 15.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGB08120.1 - 0.00087 18.3 0.0 0.0051 15.8 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB08120.1 - 0.0072 16.3 0.0 0.026 14.5 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGB08120.1 - 0.031 13.3 0.0 0.062 12.3 0.0 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 Kdo PF06293.14 EGB08120.1 - 0.045 13.1 0.1 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HECT PF00632.25 EGB08121.1 - 2e-62 211.4 0.0 2.3e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OTU PF02338.19 EGB08122.1 - 2e-10 41.3 0.0 2.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease EcpB_C PF18649.1 EGB08122.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 EcpB C-terminal domain HA PF03457.14 EGB08123.1 - 1.2e-51 172.8 12.9 2.2e-17 63.1 0.2 4.5 4 0 0 4 4 4 4 Helicase associated domain HA PF03457.14 EGB08124.1 - 5.6e-50 167.5 12.3 7e-17 61.5 0.2 4.8 5 0 0 5 5 5 4 Helicase associated domain DUF4239 PF14023.6 EGB08124.1 - 1.7e-15 57.4 0.6 3e-15 56.5 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) UCH PF00443.29 EGB08124.1 - 5.8e-10 39.1 0.0 8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 EGB08124.1 - 0.00021 21.8 0.0 0.00078 20.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Peptidase_C48 PF02902.19 EGB08124.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ank_3 PF13606.6 EGB08124.1 - 0.0033 17.8 0.1 1.2 9.9 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGB08124.1 - 0.0087 16.5 6.0 0.34 11.5 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EGB08124.1 - 0.032 14.6 0.1 0.032 14.6 0.1 3.4 4 0 0 4 4 4 0 Ankyrin repeats (many copies) UCH_1 PF13423.6 EGB08124.1 - 0.044 13.4 0.2 0.42 10.1 0.0 2.0 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase HECT PF00632.25 EGB08125.1 - 2e-62 211.4 0.0 2.3e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 EGB08126.1 - 5e-36 124.4 0.0 5.4e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08126.1 - 1.5e-35 122.7 0.0 1.9e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB08126.1 - 0.00016 20.6 0.0 0.0002 20.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB08126.1 - 0.011 15.7 0.2 1.2 9.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGB08126.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_99 PF16317.5 EGB08127.1 - 1.4e-97 326.9 0.0 1.6e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 EGB08127.1 - 0.00086 18.9 0.0 0.00086 18.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase WbsX Transcrip_reg PF01709.20 EGB08128.1 - 1.2e-49 168.9 0.5 1.3e-49 168.8 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator Methyltransf_16 PF10294.9 EGB08129.1 - 1.9e-15 57.1 0.0 2.4e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGB08129.1 - 0.0012 19.6 0.1 0.0025 18.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain TLP1_add_C PF18313.1 EGB08129.1 - 0.14 12.1 0.3 10 6.1 0.1 2.4 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain Robl_LC7 PF03259.17 EGB08129.1 - 8.1 6.3 10.5 7.5 6.4 1.2 3.1 2 1 1 3 3 3 0 Roadblock/LC7 domain NUDIX PF00293.28 EGB08130.1 - 2.3e-16 60.0 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Nudix_N_2 PF14803.6 EGB08130.1 - 1.4e-14 53.7 2.3 2.8e-14 52.7 2.3 1.6 1 0 0 1 1 1 1 Nudix N-terminal NUDIX_4 PF14815.6 EGB08130.1 - 0.0096 15.9 0.0 0.015 15.3 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain eIF-5_eIF-2B PF01873.17 EGB08130.1 - 0.3 11.0 1.4 0.47 10.3 1.4 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 KRTAP PF11759.8 EGB08132.1 - 1.7e-05 25.3 135.3 1.8e+04 -23.1 61.6 6.3 2 2 0 2 2 2 0 Keratin-associated matrix Keratin_2_head PF16208.5 EGB08132.1 - 0.47 10.6 130.7 1.8e+04 -22.3 59.8 6.5 2 2 0 2 2 2 0 Keratin type II head DnaJ PF00226.31 EGB08133.1 - 5.4e-26 90.5 0.2 6.2e-26 90.3 0.2 1.0 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGB08133.1 - 0.057 13.3 0.0 0.19 11.7 0.0 1.8 1 1 1 2 2 2 0 A repeated domain in UCH-protein Aa_trans PF01490.18 EGB08134.1 - 5.2e-61 206.6 7.5 6.6e-61 206.2 7.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGB08134.1 - 8.9e-05 21.7 7.3 0.00015 20.9 7.3 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family tRNA-synt_1b PF00579.25 EGB08135.1 - 4.4e-46 157.5 0.0 5.4e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DnaJ PF00226.31 EGB08136.1 - 4.8e-07 29.8 0.0 8.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Proteasome PF00227.26 EGB08137.1 - 5.4e-31 107.6 0.0 6.9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit CBFD_NFYB_HMF PF00808.23 EGB08138.1 - 6e-17 61.7 0.5 1.1e-16 60.9 0.5 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB08138.1 - 1.5e-10 41.5 0.7 2.1e-10 41.1 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3656 PF12392.8 EGB08138.1 - 0.052 14.2 0.0 0.063 13.9 0.0 1.1 1 0 0 1 1 1 0 Collagenase MMR_HSR1 PF01926.23 EGB08139.1 - 8.4e-40 135.4 0.0 1.6e-22 79.7 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB08139.1 - 6.4e-22 77.7 0.0 5.2e-15 55.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGB08139.1 - 2.4e-12 46.8 0.0 0.00022 20.8 0.0 4.6 4 1 0 4 4 4 2 Elongation factor Tu GTP binding domain KH_dom-like PF14714.6 EGB08139.1 - 6.9e-11 42.3 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal RsgA_GTPase PF03193.16 EGB08139.1 - 2.3e-08 34.1 0.0 0.0057 16.6 0.0 3.6 3 1 0 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 EGB08139.1 - 1.1e-07 32.1 0.0 0.02 14.9 0.0 3.4 3 1 1 4 4 3 2 Dynamin family Arf PF00025.21 EGB08139.1 - 4.6e-06 26.2 0.0 0.22 11.0 0.0 3.7 4 0 0 4 4 4 2 ADP-ribosylation factor family Roc PF08477.13 EGB08139.1 - 7.3e-06 26.2 0.0 0.24 11.6 0.0 4.0 4 1 1 5 5 5 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EGB08139.1 - 2.7e-05 24.7 0.0 0.21 12.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 EGB08139.1 - 2.9e-05 24.4 0.0 0.03 14.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.6 EGB08139.1 - 9.3e-05 22.1 3.9 0.022 14.3 1.6 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EGB08139.1 - 0.00011 21.9 0.0 0.58 10.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB08139.1 - 0.00013 22.3 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB08139.1 - 0.00013 22.5 0.0 0.23 12.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain Ras PF00071.22 EGB08139.1 - 0.00014 21.5 0.0 0.073 12.7 0.0 3.9 5 0 0 5 5 5 1 Ras family AIG1 PF04548.16 EGB08139.1 - 0.00019 20.8 0.0 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 EGB08139.1 - 0.00029 20.2 0.0 0.31 10.3 0.0 2.1 2 0 0 2 2 2 2 Septin MeaB PF03308.16 EGB08139.1 - 0.00052 19.1 0.0 0.46 9.4 0.0 3.6 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGB08139.1 - 0.0024 17.8 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 2 NTPase RNA_helicase PF00910.22 EGB08139.1 - 0.0031 17.9 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 1 RNA helicase TniB PF05621.11 EGB08139.1 - 0.0054 16.2 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 EGB08139.1 - 0.01 16.2 5.7 0.54 10.6 0.2 3.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EGB08139.1 - 0.014 15.1 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EGB08139.1 - 0.017 15.1 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TilS PF09179.11 EGB08139.1 - 0.021 15.3 2.5 8.7 6.9 0.3 3.3 2 0 0 2 2 2 0 TilS substrate binding domain NB-ARC PF00931.22 EGB08139.1 - 0.031 13.5 0.0 6.9 5.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_21 PF13304.6 EGB08139.1 - 0.034 14.0 0.0 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGB08139.1 - 0.035 14.5 0.0 0.98 9.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EGB08139.1 - 0.076 12.4 0.0 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.13 EGB08139.1 - 0.13 11.3 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) KTI12 PF08433.10 EGB08139.1 - 0.14 11.5 0.0 6.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_15 PF13175.6 EGB08139.1 - 0.15 11.8 0.0 9.4 5.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DHHC PF01529.20 EGB08140.1 - 5.4e-16 58.9 12.0 5.4e-16 58.9 12.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Virul_fac_BrkB PF03631.15 EGB08140.1 - 0.13 11.9 1.1 0.16 11.5 1.1 1.1 1 0 0 1 1 1 0 Virulence factor BrkB Sel1 PF08238.12 EGB08141.1 - 4.3e-52 173.4 61.9 1.4e-08 35.1 0.1 12.8 12 2 0 12 12 12 12 Sel1 repeat TPR_10 PF13374.6 EGB08141.1 - 1.6e-06 27.8 19.4 0.028 14.3 0.4 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB08141.1 - 0.001 19.3 35.8 0.022 15.0 1.7 7.4 6 2 4 10 10 10 5 Tetratricopeptide repeat MIT PF04212.18 EGB08141.1 - 0.003 17.6 15.0 0.17 12.0 0.2 4.9 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain B12-binding_2 PF02607.17 EGB08141.1 - 0.037 14.5 5.8 10 6.6 0.0 4.7 5 0 0 5 5 5 0 B12 binding domain TPR_1 PF00515.28 EGB08141.1 - 0.12 12.2 35.2 0.27 11.1 0.4 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat VirE_N PF08800.10 EGB08141.1 - 0.14 12.3 0.0 20 5.3 0.0 3.3 3 0 0 3 3 3 0 VirE N-terminal domain TylF PF05711.11 EGB08141.1 - 0.17 11.2 0.4 4.3 6.5 0.0 2.9 4 0 0 4 4 4 0 Macrocin-O-methyltransferase (TylF) PTR PF12789.7 EGB08141.1 - 0.21 11.7 0.0 20 5.3 0.0 2.7 3 0 0 3 3 3 0 Phage tail repeat like DUF410 PF04190.13 EGB08141.1 - 0.89 9.3 7.3 2.9 7.6 0.3 3.6 3 1 0 4 4 4 0 Protein of unknown function (DUF410) TPR_8 PF13181.6 EGB08141.1 - 4.5 7.7 23.1 1.2 9.5 0.3 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat GATase PF00117.28 EGB08142.1 - 5.9e-12 45.7 0.0 9.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGB08142.1 - 0.00021 21.1 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 WD40 PF00400.32 EGB08143.1 - 8.9e-11 42.2 15.3 0.12 13.3 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08143.1 - 1e-05 25.7 1.2 8.7 6.7 0.0 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGB08143.1 - 0.021 13.9 0.1 1.1 8.3 0.1 3.1 3 1 0 3 3 3 0 Coatomer WD associated region Ank_2 PF12796.7 EGB08144.1 - 3.9e-16 59.4 0.4 1.2e-11 45.0 0.1 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08144.1 - 6.1e-16 58.6 1.2 3e-06 27.7 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB08144.1 - 1.2e-14 54.0 2.3 0.00015 22.0 0.9 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EGB08144.1 - 4.6e-13 48.1 1.1 0.00086 19.6 0.2 4.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGB08144.1 - 8.1e-11 41.9 2.7 3.7e-07 30.3 0.7 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PIH1_CS PF18201.1 EGB08145.1 - 6.7e-09 36.1 0.0 9.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 EGB08145.1 - 0.0053 16.3 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Synaptobrevin PF00957.21 EGB08146.1 - 6.2e-29 99.6 0.1 8.8e-29 99.1 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGB08146.1 - 2.9e-17 62.5 0.0 5.1e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain PP2C PF00481.21 EGB08148.1 - 4.1e-17 62.7 0.1 4.5e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PhyH PF05721.13 EGB08149.1 - 3.1e-14 53.7 0.0 7.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Rad21_Rec8_N PF04825.13 EGB08150.1 - 2.8e-29 101.5 0.0 4.9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGB08150.1 - 2e-08 33.4 0.0 3.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein PEPCK_ATP PF01293.20 EGB08151.1 - 2.6e-199 662.7 0.0 3e-199 662.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase UAA PF08449.11 EGB08152.1 - 4.5e-35 121.3 0.4 5.5e-35 121.0 0.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB08152.1 - 0.00018 21.7 1.7 0.00018 21.7 1.7 2.2 2 0 0 2 2 2 1 EamA-like transporter family Alginate_exp PF13372.6 EGB08153.1 - 0.082 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Alginate export AAA PF00004.29 EGB08154.1 - 3.8e-16 59.7 0.0 5.6e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB08154.1 - 3.1e-06 26.9 3.4 6.1e-06 25.9 3.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain RCC1 PF00415.18 EGB08155.1 - 2e-51 172.4 31.0 8.7e-11 42.3 0.4 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB08155.1 - 1.3e-34 117.3 28.3 1.7e-09 37.3 1.1 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat MliC PF09864.9 EGB08155.1 - 7.7 6.5 6.3 1.9 8.5 0.8 2.6 3 0 0 3 3 3 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Collagen PF01391.18 EGB08156.1 - 0.0056 16.4 6.2 0.0093 15.7 6.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ABC_tran PF00005.27 EGB08157.1 - 1.5e-45 155.1 0.0 1.1e-23 84.2 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB08157.1 - 6.9e-19 68.8 1.8 0.00016 21.6 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB08157.1 - 1.8e-10 40.6 0.0 0.0052 16.3 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 EGB08157.1 - 1.6e-08 34.4 10.4 1.6e-08 34.4 10.4 2.8 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.12 EGB08157.1 - 5.4e-06 26.4 0.1 0.05 13.5 0.0 2.9 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.6 EGB08157.1 - 9.5e-06 25.8 0.0 0.0068 16.6 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGB08157.1 - 1.9e-05 24.3 0.1 0.007 16.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EGB08157.1 - 0.00017 21.5 2.3 0.17 11.5 0.1 3.2 4 0 0 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGB08157.1 - 0.0008 19.5 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EGB08157.1 - 0.00084 19.9 10.5 0.56 10.7 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 EGB08157.1 - 0.0012 19.1 0.4 3 8.1 0.2 3.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGB08157.1 - 0.0032 17.2 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB08157.1 - 0.0059 17.2 2.0 0.88 10.1 0.1 4.2 3 1 1 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 EGB08157.1 - 0.0062 16.5 0.1 0.42 10.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 EGB08157.1 - 0.0088 16.4 0.1 1.4 9.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 EGB08157.1 - 0.02 15.3 0.0 9.3 6.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EGB08157.1 - 0.028 13.6 0.1 0.75 8.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.6 EGB08157.1 - 0.034 14.3 1.7 14 5.8 0.0 3.7 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 EGB08157.1 - 0.039 14.0 5.2 0.17 12.0 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain PduV-EutP PF10662.9 EGB08157.1 - 0.044 13.5 0.1 5.1 6.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EGB08157.1 - 0.059 13.6 8.0 5.4 7.2 0.0 4.5 5 0 0 5 5 5 0 AAA domain MobB PF03205.14 EGB08157.1 - 0.072 13.0 0.1 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 EGB08157.1 - 0.078 13.0 1.6 5.6 7.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 EGB08157.1 - 0.12 12.6 0.1 3.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGB08157.1 - 0.14 12.2 2.4 7.2 6.6 0.0 3.2 3 1 0 3 3 3 0 Dynamin family AAA_16 PF13191.6 EGB08157.1 - 0.2 12.0 4.2 15 5.9 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain U1snRNP70_N PF12220.8 EGB08157.1 - 9.3 7.0 9.3 25 5.6 0.7 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EF-hand_1 PF00036.32 EGB08158.1 - 3.7e-13 48.0 3.7 6.1e-06 25.4 0.3 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB08158.1 - 2.4e-11 42.6 5.1 7.3e-07 28.6 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB08158.1 - 2.6e-09 36.1 3.3 8.3e-05 21.9 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB08158.1 - 4.6e-09 36.6 0.6 5.5e-09 36.3 0.6 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB08158.1 - 0.00016 21.5 3.4 0.00088 19.1 1.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EGB08158.1 - 0.1 12.6 1.1 0.36 10.8 0.1 1.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand WW PF00397.26 EGB08159.1 - 1.6e-17 63.3 10.5 2.9e-09 36.8 0.7 3.0 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 EGB08159.1 - 0.033 14.5 0.1 12 6.2 0.1 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Cupin_4 PF08007.12 EGB08160.1 - 2.6e-07 30.4 0.3 4e-05 23.2 0.0 2.5 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 EGB08160.1 - 0.00036 20.9 0.0 0.00099 19.5 0.0 1.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGB08160.1 - 0.0011 18.7 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 EGB08160.1 - 0.033 13.9 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Cupin domain AraC_binding PF02311.19 EGB08160.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain IU_nuc_hydro PF01156.19 EGB08161.1 - 2.8e-06 27.1 0.1 1.1e-05 25.2 0.1 1.8 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DSHCT PF08148.12 EGB08162.1 - 8e-49 165.4 2.0 1e-48 165.1 0.0 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EGB08162.1 - 3.9e-30 105.7 0.0 6.4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EGB08162.1 - 1.6e-18 67.1 0.0 4.5e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB08162.1 - 1.8e-06 28.3 0.0 7.2e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF349 PF03993.12 EGB08162.1 - 0.31 11.4 3.3 22 5.5 3.2 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) MA3 PF02847.17 EGB08163.1 - 1.4e-28 99.1 0.3 6.3e-28 97.0 0.1 2.1 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EGB08163.1 - 5.3e-11 42.6 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain MIF4G_like PF09088.11 EGB08163.1 - 0.031 14.1 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 MIF4G like Tyrosinase PF00264.20 EGB08164.1 - 5.3e-13 49.8 0.3 1.2e-11 45.3 0.1 2.2 2 0 0 2 2 2 1 Common central domain of tyrosinase WD40_4 PF16300.5 EGB08165.1 - 1.1e-11 44.4 0.0 2.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGB08165.1 - 2.5e-08 34.5 0.6 0.018 15.9 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08165.1 - 0.00034 20.9 0.0 0.23 11.8 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 EGB08165.1 - 0.029 14.2 0.2 0.054 13.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Coatomer_WDAD PF04053.14 EGB08165.1 - 0.063 12.3 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.6 EGB08165.1 - 0.064 12.8 1.4 0.11 12.1 0.3 1.7 1 1 1 2 2 2 0 PQQ-like domain Ge1_WD40 PF16529.5 EGB08165.1 - 0.078 11.9 0.0 0.54 9.2 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 EGB08165.1 - 0.13 12.2 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat PhzC-PhzF PF02567.16 EGB08166.1 - 1.4e-44 152.7 0.0 1.7e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 EGB08166.1 - 0.0086 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Proline racemase EF-hand_1 PF00036.32 EGB08167.1 - 2.9e-16 57.7 2.3 4.9e-06 25.7 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB08167.1 - 1.1e-15 56.2 1.9 0.00025 20.7 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EGB08167.1 - 4e-15 54.5 0.6 3.4e-05 23.1 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGB08167.1 - 2.9e-12 46.9 2.1 1.5e-06 28.5 0.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 EGB08167.1 - 6.2e-08 32.7 1.0 0.15 12.3 0.1 3.3 3 0 0 3 3 3 3 Dockerin type I domain EF-hand_8 PF13833.6 EGB08167.1 - 7.4e-07 28.9 4.5 0.0043 16.9 0.3 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 EGB08167.1 - 1.4e-05 24.9 3.7 0.011 15.7 0.1 3.3 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGB08167.1 - 0.011 16.1 0.1 0.76 10.1 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 EGB08167.1 - 0.026 14.5 0.3 7.3 6.5 0.0 2.6 1 1 2 3 3 3 0 Caleosin related protein FG-GAP PF01839.23 EGB08167.1 - 0.045 13.9 6.3 25 5.1 0.3 3.5 3 1 0 3 3 3 0 FG-GAP repeat VCBS PF13517.6 EGB08167.1 - 0.19 12.4 6.1 5.1 7.8 0.1 3.1 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella L51_S25_CI-B8 PF05047.16 EGB08168.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sulfatase PF00884.23 EGB08169.1 - 2e-54 185.1 0.1 2.6e-54 184.7 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 EGB08169.1 - 0.04 14.6 0.0 0.088 13.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 EGB08169.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Ala_racemase_N PF01168.20 EGB08170.1 - 6.4e-23 81.5 0.0 8.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 EGB08170.1 - 3.6e-13 50.0 0.3 6.9e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Sulfatase PF00884.23 EGB08171.1 - 3.9e-49 167.7 0.0 5.2e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase PAP2_C PF14360.6 EGB08171.1 - 5.4e-05 23.7 1.0 0.00011 22.7 1.0 1.5 1 0 0 1 1 1 1 PAP2 superfamily C-terminal DUF1501 PF07394.12 EGB08171.1 - 0.023 13.8 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) DUF229 PF02995.17 EGB08171.1 - 0.068 11.8 0.0 1.6 7.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF229) NMD3 PF04981.13 EGB08172.1 - 1.7e-64 217.6 9.2 2.2e-64 217.3 9.2 1.1 1 0 0 1 1 1 1 NMD3 family Se-cys_synth_N PF12390.8 EGB08172.1 - 0.23 11.7 5.0 0.4 11.0 2.3 2.8 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Neur_chan_LBD PF02931.23 EGB08173.1 - 1.8e-37 128.9 0.0 2.2e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Dus PF01207.17 EGB08174.1 - 7.7e-48 163.2 0.0 8.8e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Ribosomal_L18 PF17135.4 EGB08175.1 - 5.3e-87 290.1 3.7 5.8e-87 289.9 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGB08175.1 - 0.00029 21.5 0.0 0.0014 19.3 0.0 2.1 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-RING_2 PF13639.6 EGB08176.1 - 9.4e-05 22.7 3.4 9.4e-05 22.7 3.4 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EGB08176.1 - 0.00018 21.3 2.1 0.00018 21.3 2.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB08176.1 - 0.0016 18.4 1.3 0.0042 17.1 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger TUDOR_5 PF18359.1 EGB08176.1 - 0.0027 17.4 0.1 0.0061 16.2 0.1 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 zf-CXXC PF02008.20 EGB08176.1 - 0.0056 16.7 4.7 0.019 15.0 4.7 1.9 1 0 0 1 1 1 1 CXXC zinc finger domain Trigger_N PF05697.13 EGB08176.1 - 0.0082 16.5 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) PWWP PF00855.17 EGB08176.1 - 0.16 12.4 0.0 15 6.1 0.0 2.7 2 0 0 2 2 2 0 PWWP domain zf-C3HC4_2 PF13923.6 EGB08176.1 - 7 6.6 11.9 0.29 11.0 4.3 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGB08176.1 - 9.5 6.2 12.3 0.041 13.7 2.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sulfotransfer_1 PF00685.27 EGB08177.1 - 6.8e-32 111.0 0.0 1.6e-31 109.8 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB08177.1 - 2.6e-07 31.3 0.0 0.00025 21.5 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family 40S_S4_C PF16121.5 EGB08177.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus BTB_2 PF02214.22 EGB08178.1 - 9.6e-14 51.5 0.0 7.9e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Exostosin PF03016.15 EGB08178.1 - 2e-10 40.4 0.1 8.3e-10 38.3 0.1 1.9 1 1 0 1 1 1 1 Exostosin family BTB PF00651.31 EGB08178.1 - 0.00095 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Myosin_head PF00063.21 EGB08179.1 - 6.1e-183 609.7 0.0 6.9e-183 609.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB08179.1 - 0.00047 20.6 0.1 0.0025 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Hpr_kinase_C PF07475.12 EGB08179.1 - 0.0022 17.6 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.12 EGB08179.1 - 0.0027 17.0 0.2 0.0059 15.9 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 EGB08179.1 - 0.06 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SNase PF00565.17 EGB08180.1 - 2.6e-29 101.8 5.2 5.4e-09 36.5 0.2 4.1 4 0 0 4 4 4 3 Staphylococcal nuclease homologue TUDOR PF00567.24 EGB08180.1 - 1.1e-11 44.9 0.0 1.4e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Tudor domain Agenet PF05641.12 EGB08180.1 - 0.00035 21.0 2.1 0.0031 17.9 0.1 3.4 4 0 0 4 4 4 1 Agenet domain LBR_tudor PF09465.10 EGB08180.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 EGB08180.1 - 0.08 12.8 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain GST_N_3 PF13417.6 EGB08181.1 - 2.5e-14 53.4 0.0 5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB08181.1 - 1.1e-13 51.2 0.1 2.1e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB08181.1 - 6.4e-11 42.1 6.4 1.9e-10 40.6 3.4 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGB08181.1 - 1.8e-08 34.9 0.0 3.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB08181.1 - 1.2e-06 28.6 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB08181.1 - 7.4e-06 26.2 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB08181.1 - 4.7e-05 23.5 0.0 9.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGB08181.1 - 0.001 19.8 0.0 0.011 16.4 0.0 2.5 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 EGB08181.1 - 0.0016 18.6 0.1 0.0035 17.5 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin LYTB PF02401.18 EGB08182.1 - 8.8e-70 235.0 0.0 1.1e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 LytB protein BAR_3_WASP_bdg PF10456.9 EGB08182.1 - 0.012 15.1 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Ribul_P_3_epim PF00834.19 EGB08183.1 - 1e-61 207.8 0.0 1.2e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 EGB08183.1 - 0.0031 16.9 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase OMPdecase PF00215.24 EGB08183.1 - 0.024 14.3 0.1 0.038 13.6 0.1 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.21 EGB08183.1 - 0.029 13.8 0.1 0.23 10.9 0.0 2.1 2 1 0 2 2 2 0 Histidine biosynthesis protein IMPDH PF00478.25 EGB08183.1 - 0.036 13.1 1.4 2 7.3 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain QRPTase_C PF01729.19 EGB08183.1 - 0.073 12.9 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PG_binding_3 PF09374.10 EGB08183.1 - 0.14 12.5 0.0 0.49 10.7 0.1 1.8 2 0 0 2 2 2 0 Predicted Peptidoglycan domain Amidohydro_3 PF07969.11 EGB08184.1 - 9.8e-08 31.9 2.3 3.9e-06 26.6 0.2 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGB08184.1 - 0.014 14.8 0.1 1.4 8.2 0.1 2.8 3 0 0 3 3 3 0 Amidohydrolase family SRCR PF00530.18 EGB08186.1 - 2.3e-17 63.3 2.6 2.5e-17 63.2 2.6 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EGB08186.1 - 0.0029 18.1 0.8 0.0029 18.1 0.8 1.2 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain Mito_carr PF00153.27 EGB08187.1 - 2.3e-42 142.8 0.6 5.3e-14 51.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M24 PF00557.24 EGB08188.1 - 5.8e-46 156.8 0.2 6.8e-46 156.6 0.2 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 C2 PF00168.30 EGB08189.1 - 7e-31 106.6 0.0 5.2e-16 58.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain DNA_pol_A_exo1 PF01612.20 EGB08189.1 - 2.4e-11 43.7 0.0 4.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease AAA_16 PF13191.6 EGB08189.1 - 0.041 14.3 4.0 0.12 12.8 0.4 3.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EGB08189.1 - 0.083 12.5 0.0 0.083 12.5 0.0 2.7 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 EGB08189.1 - 0.13 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pro_isomerase PF00160.21 EGB08190.1 - 9e-52 175.5 0.0 1.8e-51 174.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGB08190.1 - 4.1e-10 40.1 0.3 0.0041 17.9 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGB08190.1 - 9.2e-05 21.5 0.5 0.3 10.0 0.0 3.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EGB08190.1 - 0.00012 22.3 0.0 0.26 11.6 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 EGB08190.1 - 0.014 14.9 0.1 1.2 8.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) Myosin_head PF00063.21 EGB08192.1 - 1.9e-108 363.5 0.0 1.1e-58 199.0 0.0 3.9 2 1 1 3 3 3 3 Myosin head (motor domain) AAA_22 PF13401.6 EGB08192.1 - 0.017 15.4 0.0 0.061 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGB08192.1 - 0.14 12.5 9.7 0.059 13.8 5.2 2.7 2 1 0 2 2 2 0 AAA ATPase domain UDG PF03167.19 EGB08193.1 - 2.8e-18 66.4 0.0 3.8e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily HhH-GPD PF00730.25 EGB08194.1 - 6e-14 52.4 0.0 7.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGB08194.1 - 0.0004 20.1 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif N36 PF11438.8 EGB08194.1 - 0.024 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) AAA_2 PF07724.14 EGB08195.1 - 7.7e-47 159.6 0.0 3e-44 151.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGB08195.1 - 6.2e-29 100.0 0.3 6.2e-29 100.0 0.3 1.9 2 0 0 2 2 1 1 AAA lid domain AAA PF00004.29 EGB08195.1 - 2.9e-22 79.5 0.0 2.2e-13 50.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Castor_Poll_mid PF06241.12 EGB08195.1 - 5e-22 77.8 0.0 1.3e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel ClpB_D2-small PF10431.9 EGB08195.1 - 3e-19 68.9 0.0 1.1e-18 67.1 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGB08195.1 - 5.9e-15 55.5 0.2 1e-07 32.0 0.0 4.9 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB08195.1 - 6.1e-09 36.5 1.2 0.00029 21.2 0.0 4.5 2 2 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 EGB08195.1 - 4.5e-07 29.8 0.0 0.02 14.6 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGB08195.1 - 5.7e-07 29.4 0.1 0.0045 16.7 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EGB08195.1 - 1.1e-06 28.9 0.5 0.17 12.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain TrkA_C PF02080.21 EGB08195.1 - 1.2e-06 28.3 0.8 7.4e-06 25.7 0.1 2.7 2 0 0 2 2 2 1 TrkA-C domain AAA_18 PF13238.6 EGB08195.1 - 9.9e-05 22.9 0.0 0.87 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGB08195.1 - 0.00047 20.5 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 EGB08195.1 - 0.00084 18.8 0.4 0.13 11.6 0.0 3.3 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI Clp_N PF02861.20 EGB08195.1 - 0.001 19.1 0.2 0.027 14.6 0.0 3.4 4 0 0 4 4 2 1 Clp amino terminal domain, pathogenicity island component AAA_28 PF13521.6 EGB08195.1 - 0.0012 19.2 0.0 1.5 9.0 0.0 3.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB08195.1 - 0.0012 18.7 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 EGB08195.1 - 0.0022 17.8 0.2 12 5.7 0.0 3.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGB08195.1 - 0.0026 17.8 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGB08195.1 - 0.0039 16.7 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 EGB08195.1 - 0.0048 17.1 0.0 4.9 7.4 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EGB08195.1 - 0.0086 16.6 0.0 0.72 10.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter TsaE PF02367.17 EGB08195.1 - 0.01 15.8 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGB08195.1 - 0.012 15.3 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGB08195.1 - 0.013 14.8 0.0 4.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 EGB08195.1 - 0.013 14.9 0.0 2.8 7.3 0.0 3.0 2 1 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 EGB08195.1 - 0.016 15.4 0.0 17 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 EGB08195.1 - 0.021 14.7 0.0 25 4.7 0.0 3.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Torsin PF06309.11 EGB08195.1 - 0.022 14.9 0.0 0.074 13.2 0.0 1.8 2 0 0 2 2 1 0 Torsin RsgA_GTPase PF03193.16 EGB08195.1 - 0.023 14.6 0.0 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MerR-DNA-bind PF09278.11 EGB08195.1 - 0.072 13.6 2.7 0.28 11.7 0.6 3.0 2 0 0 2 2 2 0 MerR, DNA binding AAA_19 PF13245.6 EGB08195.1 - 0.077 13.3 0.1 1.4 9.3 0.1 3.0 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 EGB08195.1 - 0.12 11.8 0.2 10 5.5 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EGB08195.1 - 0.16 11.2 0.0 9 5.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ABC_tran_CTD PF16326.5 EGB08195.1 - 5.1 7.4 11.9 1.7 8.9 2.8 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain Pro_isomerase PF00160.21 EGB08196.1 - 9.2e-46 156.0 0.1 1e-45 155.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cupin_5 PF06172.11 EGB08197.1 - 6.2e-46 156.1 0.0 7.5e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Ion_trans_2 PF07885.16 EGB08198.1 - 1.8e-14 53.4 13.0 4.6e-14 52.1 12.8 1.6 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB08198.1 - 3.8e-10 39.4 6.0 4.2e-10 39.3 6.0 1.0 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 EGB08198.1 - 0.00093 19.1 2.2 0.0014 18.5 2.2 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Glyco_hydro_3 PF00933.21 EGB08199.1 - 2.4e-26 92.9 0.0 3e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain AMP-binding PF00501.28 EGB08200.1 - 2.3e-59 201.1 0.0 3.5e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB08200.1 - 0.00024 22.0 0.1 0.0011 19.9 0.1 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-CXXC PF02008.20 EGB08201.1 - 1.5e-14 53.7 29.8 4.3e-11 42.7 16.4 4.7 4 1 1 5 5 5 2 CXXC zinc finger domain zf-CW PF07496.15 EGB08201.1 - 2.1e-11 43.7 4.9 2.1e-11 43.7 4.9 3.0 3 0 0 3 3 3 1 CW-type Zinc Finger SBP PF03110.14 EGB08201.1 - 1.7 9.0 11.3 3.1 8.2 8.8 2.8 2 0 0 2 2 2 0 SBP domain zf-TAZ PF02135.16 EGB08202.1 - 1.3e-12 48.0 5.8 2.3e-12 47.2 5.8 1.4 1 0 0 1 1 1 1 TAZ zinc finger F-box PF00646.33 EGB08202.1 - 0.028 14.3 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain DUF1282 PF06930.12 EGB08202.1 - 0.24 11.2 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) FMO-like PF00743.19 EGB08203.1 - 1.3e-52 178.9 0.0 8.5e-31 107.0 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGB08203.1 - 7.1e-18 64.9 0.0 3.5e-15 56.0 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB08203.1 - 1.5e-12 47.4 0.1 6.8e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB08203.1 - 2.3e-12 46.8 0.0 1.7e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) zf-RING_2 PF13639.6 EGB08203.1 - 9.4e-10 38.7 0.6 9.4e-10 38.7 0.6 2.4 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 EGB08203.1 - 1.5e-07 31.6 0.6 1.5e-07 31.6 0.6 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGB08203.1 - 6.6e-07 29.3 1.0 1.6e-06 28.0 1.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGB08203.1 - 1.8e-06 27.7 0.5 4e-06 26.6 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGB08203.1 - 1.8e-06 27.5 2.6 7.4e-06 25.6 2.6 2.1 1 1 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EGB08203.1 - 0.00099 19.0 0.6 0.0026 17.7 0.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGB08203.1 - 0.0015 18.3 6.7 0.0015 18.3 6.7 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGB08203.1 - 0.0088 15.9 1.4 0.032 14.1 1.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Thi4 PF01946.17 EGB08203.1 - 0.011 14.9 1.4 0.18 11.1 0.4 2.2 2 0 0 2 2 2 0 Thi4 family Zn_ribbon_17 PF17120.5 EGB08203.1 - 0.012 15.3 1.3 0.052 13.2 1.3 2.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGB08203.1 - 0.013 15.4 1.0 0.041 13.8 1.0 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 2-Hacid_dh_C PF02826.19 EGB08203.1 - 0.019 14.4 0.0 0.92 8.8 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EGB08203.1 - 0.057 14.0 1.6 0.15 12.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGB08203.1 - 0.06 13.4 0.0 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Baculo_RING PF05883.11 EGB08203.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain NAD_binding_8 PF13450.6 EGB08203.1 - 0.52 10.6 4.5 0.38 11.0 0.5 2.7 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain FANCL_C PF11793.8 EGB08203.1 - 0.96 9.7 4.5 0.42 10.8 0.3 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain GIDA PF01134.22 EGB08203.1 - 1 8.3 2.3 1.7 7.7 0.0 2.4 3 1 0 3 3 2 0 Glucose inhibited division protein A zinc_ribbon_16 PF17034.5 EGB08203.1 - 2.3 8.4 5.8 0.28 11.4 0.6 2.1 2 0 0 2 2 2 0 Zinc-ribbon like family EF-hand_1 PF00036.32 EGB08204.1 - 6e-33 109.9 10.8 1e-09 37.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB08204.1 - 2.2e-29 101.7 6.5 7.9e-15 55.1 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB08204.1 - 3e-27 92.2 7.9 5e-10 38.5 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB08204.1 - 1.1e-20 73.2 6.6 8.6e-09 35.1 0.4 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB08204.1 - 2.1e-20 71.2 9.6 1.6e-06 27.3 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGB08204.1 - 1.4e-09 38.1 0.5 0.00014 22.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGB08204.1 - 1.1e-05 25.4 4.7 0.11 12.4 0.2 3.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB08204.1 - 4.1e-05 23.9 0.6 0.33 11.3 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EGB08204.1 - 0.00024 21.4 1.1 0.063 13.6 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 EGB08204.1 - 0.00075 19.5 2.5 1.7 8.6 0.0 3.8 1 1 3 4 4 4 1 Caleosin related protein SurA_N_2 PF13623.6 EGB08204.1 - 0.0089 15.9 1.5 0.52 10.2 0.3 2.4 1 1 1 2 2 2 1 SurA N-terminal domain LETM1 PF07766.13 EGB08204.1 - 0.025 13.9 0.7 0.1 11.9 0.9 1.7 1 1 1 2 2 2 0 LETM1-like protein DUF3008 PF11450.8 EGB08204.1 - 0.028 14.6 0.2 0.028 14.6 0.2 2.1 3 0 0 3 3 2 0 Protein of unknwon function (DUF3008) DUF3349 PF11829.8 EGB08204.1 - 0.03 15.1 0.5 19 6.1 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) AAA_assoc_C PF09821.9 EGB08204.1 - 0.031 14.8 0.1 0.56 10.7 0.0 2.2 2 0 0 2 2 2 0 C-terminal AAA-associated domain Acetyltransf_11 PF13720.6 EGB08204.1 - 0.032 14.7 0.1 0.63 10.5 0.0 2.3 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TerB PF05099.13 EGB08204.1 - 0.063 13.2 1.6 1.5 8.8 0.4 2.9 1 1 1 2 2 2 0 Tellurite resistance protein TerB IF2_N PF04760.15 EGB08204.1 - 0.07 13.0 3.4 16 5.4 0.1 4.0 3 1 1 4 4 4 0 Translation initiation factor IF-2, N-terminal region Tachykinin PF02202.16 EGB08204.1 - 0.088 12.7 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Tachykinin family PMBR PF09373.10 EGB08204.1 - 0.2 11.9 0.1 24 5.3 0.0 3.7 4 1 1 5 5 5 0 Pseudomurein-binding repeat Skp1 PF01466.19 EGB08204.1 - 1.1 9.4 4.9 14 5.9 0.1 2.7 3 0 0 3 3 3 0 Skp1 family, dimerisation domain DHHC PF01529.20 EGB08205.1 - 9.5e-28 97.0 2.4 1.3e-27 96.5 2.4 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase HAD_2 PF13419.6 EGB08206.1 - 6.2e-23 81.8 0.0 9e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB08206.1 - 4.1e-11 43.6 0.0 5.1e-10 40.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RL10P_insert PF17777.1 EGB08206.1 - 3.8e-10 39.6 0.0 9.6e-10 38.3 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P SET PF00856.28 EGB08206.1 - 2.5e-06 28.0 0.0 5e-05 23.8 0.0 2.4 1 1 0 1 1 1 1 SET domain Hydrolase_like PF13242.6 EGB08206.1 - 1.4e-05 25.0 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGB08206.1 - 1.7e-05 25.3 0.3 8e-05 23.1 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PTR2 PF00854.21 EGB08208.1 - 1.6e-45 155.7 0.2 9.6e-25 87.2 0.0 2.1 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 EGB08208.1 - 9.8e-08 31.3 28.0 1.5e-07 30.7 25.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 EGB08209.1 - 1.6e-55 188.4 6.1 2.1e-55 188.0 6.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB08209.1 - 3.3e-28 98.1 0.1 9.5e-28 96.7 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB08209.1 - 6e-18 65.2 1.3 4.2e-17 62.5 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB08209.1 - 5.3e-06 25.9 0.6 7.4e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB08209.1 - 4.3e-05 22.8 9.1 0.0015 17.7 2.9 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A K_oxygenase PF13434.6 EGB08209.1 - 4.5e-05 22.8 0.0 0.00099 18.3 0.0 2.2 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGB08209.1 - 5.6e-05 22.0 4.7 0.04 12.6 0.5 3.7 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 EGB08209.1 - 0.00013 21.3 2.5 0.045 13.0 0.2 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EGB08209.1 - 0.0015 17.9 3.3 0.015 14.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGB08209.1 - 0.0017 18.5 6.7 0.036 14.3 1.7 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 EGB08209.1 - 0.0067 15.8 0.0 0.033 13.6 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EGB08209.1 - 0.021 14.7 0.1 0.021 14.7 0.1 2.0 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGB08209.1 - 0.048 13.2 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EGB08209.1 - 0.075 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 EGB08209.1 - 0.082 12.3 0.1 0.25 10.7 0.1 1.8 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 EGB08209.1 - 0.22 10.5 5.0 0.19 10.7 0.2 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGB08209.1 - 0.47 9.5 15.3 0.26 10.3 3.3 3.3 3 0 0 3 3 3 0 FAD binding domain DFP PF04127.15 EGB08209.1 - 0.58 10.0 4.5 8.5 6.2 1.4 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein FAD_oxidored PF12831.7 EGB08209.1 - 3.6 6.8 12.5 0.088 12.1 4.7 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase DEAD PF00270.29 EGB08210.1 - 2.7e-38 131.5 0.0 4.6e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB08210.1 - 2.9e-23 82.3 0.0 6.6e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGB08210.1 - 9.7e-14 51.4 1.0 2.4e-13 50.1 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGB08210.1 - 0.00058 19.9 0.0 0.00093 19.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGB08210.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PBP_like_2 PF12849.7 EGB08211.1 - 1.1e-46 159.8 1.2 1.7e-46 159.2 1.2 1.2 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 EGB08211.1 - 0.0004 20.4 0.5 0.011 15.7 0.5 2.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF2975 PF11188.8 EGB08211.1 - 0.023 14.6 0.8 0.46 10.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Sec63 PF02889.16 EGB08212.1 - 2.5e-148 492.2 0.0 4e-82 275.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGB08212.1 - 8.9e-38 129.8 0.0 5.1e-25 88.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGB08212.1 - 2.2e-35 121.2 0.0 6e-35 119.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EGB08212.1 - 2.7e-14 53.5 0.0 1.1e-11 45.1 0.0 2.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGB08212.1 - 3.3e-11 43.5 0.0 4.2e-07 30.3 0.0 3.2 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGB08212.1 - 0.0047 17.2 0.1 1.7 8.9 0.1 3.2 2 1 0 2 2 2 1 AAA domain TBSV_P22 PF03558.13 EGB08212.1 - 0.061 12.8 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 TBSV core protein P21/P22 Neur_chan_LBD PF02931.23 EGB08213.1 - 3.9e-15 55.9 0.0 6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 EGB08213.1 - 2.8e-09 37.4 0.7 4.5e-09 36.7 0.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region BTB PF00651.31 EGB08213.1 - 1.1e-08 35.3 0.0 9.7e-08 32.2 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain BACK PF07707.15 EGB08213.1 - 6.4e-05 23.0 0.0 0.00018 21.5 0.0 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch Rx_N PF18052.1 EGB08213.1 - 0.16 12.3 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Rx N-terminal domain Lipase_GDSL_2 PF13472.6 EGB08214.1 - 2.3e-27 96.5 0.2 2.3e-27 96.5 0.2 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB08214.1 - 4.8e-08 33.2 0.0 6.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase VCBS PF13517.6 EGB08215.1 - 1.4e-27 96.0 44.4 5.6e-12 46.1 4.1 5.8 3 2 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UPF0086 PF01868.16 EGB08215.1 - 1.2e-10 41.1 0.0 2.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 FG-GAP PF01839.23 EGB08215.1 - 9.6e-09 35.2 49.1 0.0062 16.7 1.6 7.9 7 0 0 7 7 7 5 FG-GAP repeat cNMP_binding PF00027.29 EGB08215.1 - 0.0017 18.3 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TcdB_toxin_midN PF12256.8 EGB08215.1 - 0.011 15.2 17.6 1.5 8.2 0.1 6.2 5 2 2 7 7 7 0 Insecticide toxin TcdB middle/N-terminal region Pkinase PF00069.25 EGB08218.1 - 7.6e-58 195.9 0.0 1.2e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08218.1 - 1.4e-22 80.3 0.0 2.2e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGB08218.1 - 3.5e-18 63.7 1.1 2.7e-05 23.4 0.7 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGB08218.1 - 8.9e-17 61.3 1.2 2.7e-08 34.1 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB08218.1 - 9.2e-16 56.4 1.3 0.0056 16.5 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB08218.1 - 4.1e-11 42.6 2.8 0.00016 21.4 0.0 3.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB08218.1 - 7.7e-10 37.8 3.0 0.013 15.0 0.3 4.3 4 0 0 4 4 4 3 EF hand Kdo PF06293.14 EGB08218.1 - 2.5e-05 23.7 0.0 7.2e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB08218.1 - 0.005 16.8 1.6 0.0098 15.8 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_4 PF12763.7 EGB08218.1 - 0.0087 16.0 3.8 4 7.4 0.1 3.1 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.6 EGB08218.1 - 0.052 12.9 0.0 22 4.3 0.0 3.0 3 0 0 3 3 3 0 Kinase-like Glycos_transf_1 PF00534.20 EGB08219.1 - 1.6e-10 40.8 0.0 3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGB08219.1 - 6.1e-06 26.7 0.0 1.9e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGB08219.1 - 0.13 12.7 0.0 0.73 10.3 0.0 2.3 1 1 0 1 1 1 0 Glycosyl transferases group 1 Cons_hypoth95 PF03602.15 EGB08220.1 - 6.2e-08 32.5 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 EGB08220.1 - 2.4e-05 23.9 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGB08220.1 - 3e-05 24.6 0.1 0.00016 22.3 0.2 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGB08220.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EGB08220.1 - 0.032 15.0 0.0 0.08 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGB08220.1 - 0.17 11.7 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Hydrolase_4 PF12146.8 EGB08221.1 - 5.6e-07 29.1 0.0 0.00049 19.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB08221.1 - 1.5e-05 24.8 0.0 5.2e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold AAA_16 PF13191.6 EGB08222.1 - 4.1e-09 37.0 2.3 1.8e-08 35.0 2.3 2.1 1 0 0 1 1 1 1 AAA ATPase domain 2OG-FeII_Oxy_5 PF13759.6 EGB08222.1 - 2.2e-08 34.4 0.0 2.2e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase NACHT PF05729.12 EGB08222.1 - 1.2e-05 25.3 0.0 2.9e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 NACHT domain Peptidase_S8_N PF16361.5 EGB08222.1 - 2.1e-05 25.1 0.0 4.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal of Subtilase family WD40 PF00400.32 EGB08222.1 - 0.0022 18.8 3.9 4.8 8.2 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08222.1 - 0.057 13.7 0.1 6.9 7.0 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PIF1 PF05970.14 EGB08222.1 - 0.099 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase TrwB_AAD_bind PF10412.9 EGB08222.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KAP_NTPase PF07693.14 EGB08222.1 - 0.29 10.3 0.0 2.5 7.3 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain PP2C PF00481.21 EGB08223.1 - 6.3e-34 117.8 0.1 7.7e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB08223.1 - 0.0034 17.0 0.8 0.018 14.7 0.8 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Cupin_2 PF07883.11 EGB08223.1 - 0.15 11.8 0.1 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Nramp PF01566.18 EGB08224.1 - 1.4e-104 349.9 14.8 1.4e-104 349.9 14.8 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein FAA_hydrolase PF01557.18 EGB08225.1 - 1.6e-53 181.6 0.0 1.8e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldo_ket_red PF00248.21 EGB08226.1 - 3.6e-34 118.3 0.0 4.1e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 EGB08227.1 - 2.3e-06 27.3 0.0 0.5 10.2 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGB08227.1 - 0.14 12.3 0.1 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Hydrolase_4 PF12146.8 EGB08228.1 - 1.1e-16 60.8 2.7 5e-11 42.3 2.6 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB08228.1 - 8.7e-08 32.1 0.9 0.003 17.3 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB08228.1 - 5.7e-06 26.0 0.1 2.8e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGB08228.1 - 8e-06 25.6 0.2 0.0035 17.0 0.9 2.0 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGB08228.1 - 7e-05 23.5 8.7 0.00021 21.9 6.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.14 EGB08228.1 - 0.0036 16.7 0.3 0.21 10.9 0.5 2.0 2 0 0 2 2 2 1 Secretory lipase DLH PF01738.18 EGB08228.1 - 0.17 11.5 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family CAP_GLY PF01302.25 EGB08229.1 - 1.5e-22 79.4 2.5 1.6e-22 79.2 2.5 1.0 1 0 0 1 1 1 1 CAP-Gly domain DUF3157 PF11355.8 EGB08230.1 - 0.00051 19.7 0.0 0.59 9.7 0.0 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3157) SapA PF02199.15 EGB08230.1 - 0.53 10.6 4.0 53 4.2 0.0 4.6 4 0 0 4 4 4 0 Saposin A-type domain Na_Ca_ex PF01699.24 EGB08231.1 - 8.7e-41 139.4 25.0 1.3e-21 77.2 6.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 EGB08231.1 - 1.8e-13 50.5 0.4 8.1e-13 48.4 0.0 2.2 2 0 0 2 2 2 1 Calx-beta domain ubiquitin PF00240.23 EGB08232.1 - 6.3e-08 32.3 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.12 EGB08232.1 - 6.3e-08 33.2 0.0 0.00028 21.5 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain NUDIX PF00293.28 EGB08232.1 - 1.1e-06 28.7 0.0 3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain EF-hand_1 PF00036.32 EGB08232.1 - 4.9e-06 25.7 0.8 0.019 14.5 0.0 2.9 2 0 0 2 2 2 2 EF hand Glyco_transf_15 PF01793.16 EGB08232.1 - 2.9e-05 23.5 2.4 0.00021 20.6 0.4 2.1 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase EF-hand_5 PF13202.6 EGB08232.1 - 5.6e-05 22.5 3.7 0.016 14.7 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB08232.1 - 0.00017 21.2 0.1 0.88 9.7 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain Methyltransf_25 PF13649.6 EGB08232.1 - 0.00025 21.7 0.0 0.056 14.2 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain EF-hand_8 PF13833.6 EGB08232.1 - 0.0011 18.8 0.1 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair Methyltransf_12 PF08242.12 EGB08232.1 - 0.038 14.7 0.0 5.1 7.9 0.0 3.0 2 0 0 2 2 2 0 Methyltransferase domain EF-hand_7 PF13499.6 EGB08232.1 - 0.067 13.7 0.0 14 6.3 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair Rad60-SLD_2 PF13881.6 EGB08232.1 - 0.14 12.3 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGB08232.1 - 0.2 12.3 0.0 0.46 11.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ABC1 PF03109.16 EGB08233.1 - 3.7e-16 59.3 0.0 6.9e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family zf-MYND PF01753.18 EGB08233.1 - 4.7e-12 45.8 15.8 1.2e-11 44.5 15.8 1.7 1 0 0 1 1 1 1 MYND finger FKBP_C PF00254.28 EGB08233.1 - 3.2e-09 37.0 0.0 1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-HIT PF04438.16 EGB08233.1 - 0.37 10.7 10.9 0.79 9.6 10.9 1.5 1 0 0 1 1 1 0 HIT zinc finger APH PF01636.23 EGB08233.1 - 0.84 9.5 15.7 0.25 11.3 9.1 3.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family zf-C6H2 PF15801.5 EGB08233.1 - 1.7 9.0 10.1 4.3 7.7 10.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ADK PF00406.22 EGB08234.1 - 1.4e-22 80.4 0.0 5.8e-20 71.9 0.0 2.0 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 EGB08234.1 - 4.9e-10 40.0 0.0 4.7e-09 36.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 EGB08234.1 - 0.098 12.9 0.1 4.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NUDIX PF00293.28 EGB08235.1 - 1.1e-08 35.2 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Plectin PF00681.20 EGB08235.1 - 0.049 13.5 0.0 0.92 9.4 0.0 2.7 2 0 0 2 2 2 0 Plectin repeat MFS_1 PF07690.16 EGB08236.1 - 3.1e-12 46.1 34.1 3.1e-12 46.1 34.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 EGB08237.1 - 0.00058 19.2 0.1 0.0055 16.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB08237.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CBFD_NFYB_HMF PF00808.23 EGB08239.1 - 4.3e-18 65.4 1.0 4.8e-18 65.2 1.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB08239.1 - 0.00037 20.9 0.2 0.0004 20.8 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGB08239.1 - 0.0033 17.5 0.1 0.0043 17.1 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF2884 PF11101.8 EGB08239.1 - 0.096 12.2 0.2 0.11 12.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) AAA_lid_2 PF17863.1 EGB08239.1 - 0.097 12.5 0.6 0.16 11.9 0.2 1.5 2 0 0 2 2 2 0 AAA lid domain Yip1 PF04893.17 EGB08240.1 - 8.5e-13 48.4 10.0 1.1e-12 48.1 10.0 1.1 1 0 0 1 1 1 1 Yip1 domain DUF1449 PF07290.11 EGB08240.1 - 0.093 12.3 1.2 0.14 11.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) HAT PF02184.16 EGB08241.1 - 8.3e-14 51.3 58.5 4.5e-07 29.7 0.6 13.8 14 1 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EGB08241.1 - 1.5e-12 47.2 64.0 0.0053 17.5 0.2 13.6 6 4 7 14 14 14 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGB08241.1 - 2.1e-07 30.9 4.0 1.2 9.7 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB08241.1 - 1.2e-06 28.9 13.7 0.00012 22.5 0.2 5.9 4 2 4 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB08241.1 - 5.3e-06 26.2 3.2 14 6.2 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB08241.1 - 0.00083 19.8 14.3 30 5.5 0.2 8.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB08241.1 - 0.0061 17.2 60.4 1.1 9.9 5.8 9.3 5 4 3 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB08241.1 - 0.0078 15.9 3.7 15 5.4 0.0 5.8 7 0 0 7 7 7 0 TPR repeat Lipase_GDSL_2 PF13472.6 EGB08241.1 - 0.019 15.4 0.2 0.059 13.8 0.2 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Mad3_BUB1_I PF08311.12 EGB08241.1 - 0.12 12.4 19.6 9.3 6.3 1.5 7.1 5 1 0 6 6 6 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGB08241.1 - 0.3 11.3 31.4 2 8.8 0.4 9.6 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB08241.1 - 0.92 9.8 31.6 2.7 8.3 0.1 7.3 7 2 1 8 8 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGB08241.1 - 1.8 8.2 11.4 1.2 8.8 1.4 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain U3_assoc_6 PF08640.11 EGB08241.1 - 3.1 7.9 17.8 0.21 11.7 0.9 5.7 6 1 1 7 7 7 0 U3 small nucleolar RNA-associated protein 6 Ebp2 PF05890.12 EGB08243.1 - 2.3e-54 184.8 19.8 4.9e-54 183.7 19.8 1.5 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Phage_P2_GpE PF06528.12 EGB08243.1 - 0.015 14.8 0.6 0.034 13.7 0.6 1.6 1 0 0 1 1 1 0 Phage P2 GpE Sulfotransfer_3 PF13469.6 EGB08244.1 - 0.00017 22.0 0.0 0.00052 20.5 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family TPR_14 PF13428.6 EGB08244.1 - 0.0039 17.9 46.0 0.0057 17.4 0.6 9.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB08244.1 - 0.1 12.7 4.4 0.38 10.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB08244.1 - 0.15 12.3 0.1 26 5.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_28 PF13521.6 EGB08244.1 - 0.59 10.4 2.4 2 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain TPR_4 PF07721.14 EGB08244.1 - 2.2 9.1 0.0 2.2 9.1 0.0 12.2 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB08244.1 - 2.9 8.5 48.6 0.93 10.0 0.1 8.8 7 2 1 9 9 9 0 Tetratricopeptide repeat Cupin_8 PF13621.6 EGB08245.1 - 4.8e-06 26.5 0.0 8.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB08245.1 - 3.9e-05 23.3 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGB08245.1 - 0.055 13.9 0.2 0.35 11.3 0.2 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase UPF0014 PF03649.13 EGB08246.1 - 0.12 11.7 0.2 0.12 11.7 0.2 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0014) LapA_dom PF06305.11 EGB08246.1 - 5.4 6.9 5.1 11 5.9 0.1 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain VCBS PF13517.6 EGB08247.1 - 2.8e-39 133.5 76.2 2e-11 44.3 5.8 9.1 5 2 6 11 11 11 9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB08247.1 - 5.9e-17 61.5 88.0 0.00029 20.9 3.0 11.2 10 0 0 10 10 10 8 FG-GAP repeat Ephrin_rec_like PF07699.13 EGB08247.1 - 1.2e-08 34.6 9.0 1.2e-08 34.6 9.0 7.1 7 0 0 7 7 7 2 Putative ephrin-receptor like BBS2_Mid PF14783.6 EGB08247.1 - 0.00011 22.2 1.0 3.3 7.8 0.0 6.3 7 0 0 7 7 7 1 Ciliary BBSome complex subunit 2, middle region TcdB_toxin_midN PF12256.8 EGB08247.1 - 0.0012 18.3 22.6 0.98 8.8 0.2 6.8 6 2 1 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Laminin_EGF PF00053.24 EGB08247.1 - 0.0026 17.9 7.3 0.0026 17.9 7.3 8.5 6 3 1 7 7 7 3 Laminin EGF domain EGF PF00008.27 EGB08247.1 - 0.0026 18.0 18.7 0.019 15.3 1.7 4.4 3 0 0 3 3 3 2 EGF-like domain Itfg2 PF15907.5 EGB08247.1 - 0.012 14.7 6.4 5.4 6.0 0.0 5.3 7 0 0 7 7 7 0 Integrin-alpha FG-GAP repeat-containing protein 2 WD40 PF00400.32 EGB08247.1 - 0.6 11.1 10.2 42 5.2 0.0 6.2 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-RING_6 PF14835.6 EGB08247.1 - 6.1 6.8 6.8 40 4.2 6.8 2.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Asp_Arg_Hydrox PF05118.15 EGB08248.1 - 1.2e-36 125.9 0.0 2e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Prefoldin_2 PF01920.20 EGB08249.1 - 8e-12 45.1 0.7 9.3e-12 44.8 0.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit PI3K_P85_iSH2 PF16454.5 EGB08249.1 - 0.044 13.4 3.2 0.31 10.6 0.2 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KASH_CCD PF14662.6 EGB08249.1 - 0.051 13.4 3.0 0.69 9.7 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4055 PF13264.6 EGB08249.1 - 0.057 13.6 0.2 0.093 12.9 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) PilJ PF13675.6 EGB08249.1 - 0.15 12.1 0.5 0.27 11.2 0.5 1.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term ABC_tran_CTD PF16326.5 EGB08249.1 - 0.46 10.8 8.9 0.31 11.3 2.9 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Torus PF16131.5 EGB08250.1 - 1.3e-30 106.3 0.8 1.8e-30 105.8 0.8 1.2 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 EGB08250.1 - 4.1e-05 23.3 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.18 EGB08252.1 - 8.3e-102 340.9 5.4 9.4e-102 340.7 5.4 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase CTP_transf_like PF01467.26 EGB08253.1 - 0.0014 18.8 0.0 0.0072 16.5 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like FlxA PF14282.6 EGB08255.1 - 0.012 15.5 6.8 0.025 14.6 6.8 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF2316 PF10078.9 EGB08255.1 - 0.073 13.3 5.0 0.57 10.4 0.8 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Sec2p PF06428.11 EGB08255.1 - 0.091 12.7 11.1 0.24 11.4 11.1 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGB08255.1 - 0.54 10.4 4.9 1 9.6 4.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 EGB08255.1 - 1.2 9.6 9.8 2.8 8.4 9.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-R PF06729.12 EGB08255.1 - 1.9 8.4 7.9 1.8 8.5 5.4 2.3 2 1 1 3 3 3 0 Kinetochore component, CENP-R WW PF00397.26 EGB08256.1 - 2.4e-42 142.7 26.6 2.6e-14 53.0 3.9 3.3 3 0 0 3 3 3 3 WW domain LBR_tudor PF09465.10 EGB08256.1 - 0.002 17.9 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 EGB08256.1 - 0.0029 17.3 0.3 0.0074 16.0 0.2 1.8 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 Peptidase_S8_N PF16361.5 EGB08256.1 - 0.017 15.6 0.0 0.017 15.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal of Subtilase family Ish1 PF10281.9 EGB08256.1 - 0.031 14.6 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF4407 PF14362.6 EGB08256.1 - 0.73 9.1 9.0 1 8.7 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pribosyltran_N PF13793.6 EGB08257.1 - 2.7e-48 162.7 0.0 1.4e-47 160.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGB08257.1 - 2.5e-26 92.9 0.0 4.5e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain SPX PF03105.19 EGB08257.1 - 5.3e-25 89.1 2.8 2.1e-09 37.8 0.0 3.1 2 1 1 3 3 3 3 SPX domain Pribosyltran PF00156.27 EGB08257.1 - 7e-16 58.1 0.6 2.1e-14 53.3 0.2 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase domain dUTPase PF00692.19 EGB08258.1 - 2.6e-40 137.1 0.0 2.9e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 dUTPase FtsZ_C PF12327.8 EGB08258.1 - 0.096 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsZ family, C-terminal domain DUF4567 PF15131.6 EGB08259.1 - 1 9.5 5.1 15 5.7 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4567) WD40 PF00400.32 EGB08260.1 - 2.1e-18 66.3 21.5 0.00018 22.2 0.6 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08260.1 - 7.2e-06 26.2 0.5 3.1 8.2 0.1 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB08260.1 - 0.0084 14.8 0.1 0.026 13.2 0.1 1.7 1 1 1 2 2 2 1 Nucleoporin Nup120/160 IlvN PF07991.12 EGB08261.1 - 4.6e-56 188.9 0.1 7.4e-56 188.2 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EGB08261.1 - 1.4e-49 168.1 0.2 2.2e-27 96.1 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.21 EGB08261.1 - 6.5e-05 23.0 0.2 0.00013 22.1 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGB08261.1 - 6.7e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGB08261.1 - 0.0057 16.3 0.1 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EGB08261.1 - 0.0078 16.6 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding PhyH PF05721.13 EGB08262.1 - 5.9e-15 56.1 1.8 1.4e-14 54.9 0.1 2.3 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Amidase02_C PF12123.8 EGB08262.1 - 0.2 11.4 0.0 10 5.9 0.0 2.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Actin PF00022.19 EGB08263.1 - 3.3e-144 480.5 0.0 1.1e-143 478.8 0.0 1.6 1 1 0 1 1 1 1 Actin INCENP_ARK-bind PF03941.15 EGB08264.1 - 0.044 13.7 2.3 0.12 12.3 2.3 1.7 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region ECH_1 PF00378.20 EGB08265.1 - 1.6e-40 139.0 0.0 3.4e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB08265.1 - 1e-13 51.5 0.0 1.6e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pex24p PF06398.11 EGB08265.1 - 0.0001 21.5 6.5 0.00016 20.8 6.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF2457 PF10446.9 EGB08266.1 - 0.0028 16.9 15.0 0.0028 16.9 15.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) UBA PF00627.31 EGB08266.1 - 0.023 14.6 0.5 0.023 14.6 0.5 2.2 2 0 0 2 2 2 0 UBA/TS-N domain Nop14 PF04147.12 EGB08266.1 - 3.5 5.7 12.8 5.8 5.0 12.8 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EGB08266.1 - 5.2 5.5 9.2 8.9 4.7 9.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 EGB08266.1 - 7.7 6.2 12.1 7.5 6.2 8.0 2.3 2 0 0 2 2 2 0 FAM176 family OmpA PF00691.20 EGB08267.1 - 1.5e-08 34.9 0.0 5.6e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 OmpA family Oxidored_q6 PF01058.22 EGB08268.1 - 1.5e-23 83.0 0.0 1.9e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit PPARgamma_N PF12577.8 EGB08268.1 - 0.11 13.1 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 PPAR gamma N-terminal region Ank_2 PF12796.7 EGB08269.1 - 1.8e-11 44.4 0.2 6.2e-06 26.7 0.5 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08269.1 - 6.6e-07 29.8 6.4 0.00059 20.3 0.2 5.1 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Synaptobrevin PF00957.21 EGB08269.1 - 1.6e-05 24.6 0.8 2.8e-05 23.8 0.8 1.3 1 0 0 1 1 1 1 Synaptobrevin Ank_5 PF13857.6 EGB08269.1 - 3.3e-05 24.1 4.2 0.0014 18.9 0.3 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB08269.1 - 6.6e-05 23.2 11.7 0.67 10.5 0.2 5.7 5 0 0 5 5 5 2 Ankyrin repeat PDZ PF00595.24 EGB08269.1 - 0.00052 20.3 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ank_3 PF13606.6 EGB08269.1 - 0.00096 19.4 4.9 16 6.5 0.1 4.8 5 0 0 5 5 5 1 Ankyrin repeat PDZ_2 PF13180.6 EGB08269.1 - 0.043 14.1 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain GATase_7 PF13537.6 EGB08269.1 - 0.15 12.0 0.4 5.4 7.0 0.1 2.5 1 1 1 2 2 2 0 Glutamine amidotransferase domain cNMP_binding PF00027.29 EGB08272.1 - 8.7e-36 121.9 0.2 2.5e-19 69.1 0.0 2.6 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4846 PF16138.5 EGB08272.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (4846) DUF3783 PF12646.7 EGB08272.1 - 0.035 14.0 0.4 5.8 7.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) KH_1 PF00013.29 EGB08273.1 - 2.1e-07 30.7 0.6 4.8e-07 29.5 0.2 1.8 2 1 0 2 2 2 1 KH domain ELO PF01151.18 EGB08274.1 - 7.9e-56 189.4 28.4 8.9e-56 189.2 28.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SWIM PF04434.17 EGB08276.1 - 0.013 15.1 0.2 0.026 14.2 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger MMACHC PF16690.5 EGB08276.1 - 0.16 11.6 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type C family TFIIA PF03153.13 EGB08277.1 - 0.021 14.8 21.0 0.049 13.6 21.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arm PF00514.23 EGB08278.1 - 1e-25 88.9 10.4 9.7e-08 31.8 0.0 4.1 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EGB08278.1 - 5.2e-09 36.0 0.1 0.0032 17.5 0.0 2.5 2 1 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Glyco_hydro_30C PF17189.4 EGB08278.1 - 0.0072 16.5 0.3 2.1 8.6 0.1 2.9 3 0 0 3 3 3 1 Glycosyl hydrolase family 30 beta sandwich domain CRS1_YhbY PF01985.21 EGB08278.1 - 0.0088 16.2 0.0 12 6.2 0.0 3.0 3 0 0 3 3 3 1 CRS1 / YhbY (CRM) domain HEAT_EZ PF13513.6 EGB08278.1 - 0.0097 16.4 11.7 0.066 13.7 1.4 2.8 2 1 1 3 3 3 3 HEAT-like repeat Aconitase_B_N PF11791.8 EGB08278.1 - 0.018 15.1 0.1 35 4.4 0.0 3.0 1 1 2 3 3 3 0 Aconitate B N-terminal domain SASP_gamma PF04259.14 EGB08278.1 - 0.071 13.6 3.0 0.61 10.6 3.3 2.1 1 1 1 2 2 2 0 Small, acid-soluble spore protein, gamma-type Peptidase_C1 PF00112.23 EGB08280.1 - 2.8e-49 168.2 0.7 3.9e-49 167.7 0.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB08280.1 - 2.8e-09 37.3 0.5 4.9e-09 36.5 0.5 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) ATP-cone PF03477.16 EGB08282.1 - 3.2e-19 69.3 0.5 6.2e-19 68.4 0.1 1.6 2 0 0 2 2 2 1 ATP cone domain RB_B PF01857.20 EGB08282.1 - 0.019 15.0 0.2 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Phage_capsid PF05065.13 EGB08282.1 - 0.1 11.9 0.7 0.24 10.6 0.5 1.7 1 1 1 2 2 2 0 Phage capsid family DSPc PF00782.20 EGB08283.1 - 0.00039 20.2 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGB08283.1 - 0.00091 19.3 0.2 0.0013 18.7 0.2 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGB08283.1 - 0.028 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGB08283.1 - 0.049 13.8 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_L17 PF01196.19 EGB08284.1 - 6.5e-35 119.9 0.1 7.6e-35 119.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L17 Ribosomal_L18A PF01775.17 EGB08284.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A ICL PF00463.21 EGB08285.1 - 1.9e-157 525.0 0.0 8.2e-155 516.3 0.0 2.1 1 1 0 1 1 1 1 Isocitrate lyase family Pkinase PF00069.25 EGB08285.1 - 6.4e-61 206.0 0.0 8.6e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08285.1 - 1.1e-28 100.2 0.2 2.6e-28 99.0 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PhyH PF05721.13 EGB08285.1 - 1.6e-09 38.3 0.2 3.2e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Kdo PF06293.14 EGB08285.1 - 0.14 11.5 0.1 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Laminin_G_3 PF13385.6 EGB08286.1 - 5.1e-21 75.4 2.9 1.2e-20 74.2 2.9 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily ABC2_membrane_3 PF12698.7 EGB08286.1 - 1.6e-08 34.1 0.1 3.6e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein GST_N PF02798.20 EGB08286.1 - 3.8e-05 23.9 0.0 0.00011 22.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB08286.1 - 0.0021 18.4 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB08286.1 - 0.0083 16.3 0.0 0.024 14.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB08286.1 - 0.013 15.5 1.4 0.079 13.0 1.4 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5308 PF17233.2 EGB08286.1 - 0.07 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5308) KRTAP PF11759.8 EGB08286.1 - 2.4 8.7 63.1 1.8e+04 -26.0 63.1 4.0 1 1 0 1 1 1 0 Keratin-associated matrix Peptidase_C1 PF00112.23 EGB08287.1 - 1.8e-65 221.1 0.9 2.3e-65 220.7 0.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB08287.1 - 3.5e-09 36.9 0.2 6.2e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB08287.1 - 2.6e-05 23.2 2.6 0.0091 14.8 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 EGB08287.1 - 0.056 13.3 0.1 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase family C1 propeptide Rad60-SLD PF11976.8 EGB08288.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Solute_trans_a PF03619.16 EGB08289.1 - 1.1e-68 231.6 2.0 1.3e-68 231.5 2.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha O-FucT PF10250.9 EGB08290.1 - 2.4e-18 66.9 0.0 1.4e-08 34.9 0.0 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase MFS_1 PF07690.16 EGB08290.1 - 1.2e-14 54.0 38.3 8.6e-14 51.2 21.4 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB08290.1 - 1.4e-05 24.2 7.0 1.4e-05 24.2 7.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter LON_substr_bdg PF02190.16 EGB08290.1 - 0.0051 16.7 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Jiraiya PF15038.6 EGB08290.1 - 0.16 11.4 0.7 0.37 10.2 0.7 1.5 1 0 0 1 1 1 0 Jiraiya EF-hand_7 PF13499.6 EGB08291.1 - 0.0024 18.3 1.6 0.068 13.6 2.5 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB08291.1 - 0.0035 16.8 0.1 0.012 15.1 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGB08291.1 - 0.092 12.7 2.9 0.16 12.0 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 EGB08291.1 - 1.4 8.8 3.8 1.1 9.1 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain pair UPF0029 PF01205.19 EGB08292.1 - 4.1e-26 91.4 0.1 6.4e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Stc1 PF12898.7 EGB08292.1 - 3.1e-05 24.4 0.6 3.1e-05 24.4 0.6 1.7 2 0 0 2 2 2 1 Stc1 domain RWD PF05773.22 EGB08292.1 - 8.2e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 1 0 1 1 1 1 RWD domain Zn_ribbon_2 PF12674.7 EGB08292.1 - 0.044 14.4 0.3 0.095 13.4 0.3 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain Acetyltransf_7 PF13508.7 EGB08293.1 - 1.8e-06 28.3 0.0 7.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGB08293.1 - 2.1e-05 24.7 0.1 5e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGB08293.1 - 4.2e-05 23.5 0.0 9.6e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB08293.1 - 0.00024 21.0 0.3 0.0073 16.3 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein LRR_8 PF13855.6 EGB08294.1 - 2.6e-24 84.7 9.3 7.8e-13 48.0 1.7 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGB08294.1 - 3.6e-12 46.3 13.2 0.00033 21.0 0.1 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EGB08294.1 - 1.3e-08 34.8 0.0 1.6e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EGB08294.1 - 1e-05 25.4 3.3 0.87 10.4 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 EGB08294.1 - 0.0021 17.6 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat PP2C PF00481.21 EGB08295.1 - 4.4e-38 131.4 0.0 5e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB08295.1 - 0.00014 21.6 8.3 0.00026 20.7 8.3 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C ABC1 PF03109.16 EGB08296.1 - 1.1e-23 83.6 0.0 3.1e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 ABC1 family DUF383 PF04063.14 EGB08296.1 - 0.00012 21.8 0.0 6.2 6.4 0.0 5.2 3 3 1 5 5 5 2 Domain of unknown function (DUF383) Arm_2 PF04826.13 EGB08296.1 - 0.00043 19.8 0.9 3.2 7.2 0.0 4.8 5 2 0 5 5 5 2 Armadillo-like Pro_isomerase PF00160.21 EGB08296.1 - 0.00089 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RICTOR_N PF14664.6 EGB08296.1 - 0.043 12.8 0.7 0.13 11.2 0.7 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Pkinase PF00069.25 EGB08296.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain PseudoU_synth_1 PF01416.20 EGB08297.1 - 1.7e-30 105.7 0.0 3.5e-28 98.2 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ribonuc_red_lgC PF02867.15 EGB08298.1 - 1.9e-178 594.3 0.0 2.9e-178 593.7 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGB08298.1 - 3.4e-24 84.7 0.1 9.8e-24 83.2 0.1 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGB08298.1 - 6e-18 65.2 0.1 1.5e-17 63.9 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain Ribonuc_red_sm PF00268.21 EGB08299.1 - 2.5e-112 374.9 0.1 3e-112 374.7 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Asp_Arg_Hydrox PF05118.15 EGB08300.1 - 4.6e-33 114.3 0.0 8.6e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase RNA_polI_A34 PF08208.11 EGB08300.1 - 5.2e-05 23.4 18.2 0.00014 22.1 18.2 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 EGB08300.1 - 0.0083 14.5 15.1 0.012 13.9 15.1 1.2 1 0 0 1 1 1 1 CDC45-like protein SR-25 PF10500.9 EGB08300.1 - 0.026 14.1 15.1 0.047 13.3 15.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein eIF3_subunit PF08597.10 EGB08300.1 - 0.035 14.0 25.3 0.066 13.1 25.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DDRGK PF09756.9 EGB08300.1 - 1.2 8.7 14.6 2.2 7.8 14.6 1.4 1 0 0 1 1 1 0 DDRGK domain Rtf2 PF04641.12 EGB08300.1 - 1.7 7.9 12.0 2.8 7.2 12.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger PGA2 PF07543.12 EGB08300.1 - 1.9 8.5 12.5 4.3 7.3 12.5 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 PTPRCAP PF15713.5 EGB08300.1 - 2 8.7 14.0 4.5 7.6 14.0 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4603 PF15376.6 EGB08300.1 - 2.1 5.6 9.5 2.8 5.2 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Rrn6 PF10214.9 EGB08300.1 - 3.3 6.1 13.3 4.3 5.7 5.3 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor GAGA_bind PF06217.12 EGB08300.1 - 5.8 7.1 9.2 12 6.1 9.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family PCRF PF03462.18 EGB08302.1 - 1.2e-32 113.4 0.0 1.8e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EGB08302.1 - 7e-29 100.1 0.0 1e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 RF-1 domain Ras PF00071.22 EGB08303.1 - 6.5e-42 142.9 0.1 7.4e-42 142.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB08303.1 - 4.1e-11 43.1 0.0 5.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGB08303.1 - 0.003 17.0 0.1 0.0062 16.0 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGB08303.1 - 0.003 17.1 0.1 0.24 10.9 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGB08303.1 - 0.0038 16.8 0.0 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 EGB08303.1 - 0.023 14.7 0.1 0.065 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EGB08303.1 - 0.025 14.0 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB08303.1 - 0.034 14.2 0.0 0.042 13.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB08303.1 - 0.057 13.8 0.1 0.09 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain HEM4 PF02602.15 EGB08304.1 - 6.4e-34 117.3 4.0 8.3e-34 116.9 4.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD LytR_C PF13399.6 EGB08304.1 - 6.1 7.9 8.6 3.8 8.6 1.7 3.2 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator DnaJ PF00226.31 EGB08305.1 - 0.00013 22.0 0.0 0.00032 20.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain UCR_14kD PF02271.16 EGB08306.1 - 3.2e-21 75.2 1.6 3.5e-21 75.0 1.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Glyco_hydro_31 PF01055.26 EGB08307.1 - 2.2e-68 231.5 0.0 3.2e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 EGB08307.1 - 4e-06 27.0 0.0 9.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 EGB08307.1 - 0.00015 22.0 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Actin PF00022.19 EGB08310.1 - 1e-78 264.8 0.0 2.1e-45 155.0 0.0 2.1 1 1 1 2 2 2 2 Actin Pyr_redox_2 PF07992.14 EGB08311.1 - 7.1e-66 222.4 1.1 1.1e-65 221.8 0.9 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB08311.1 - 9.7e-40 135.3 0.4 3e-39 133.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB08311.1 - 3.7e-21 75.5 6.4 9.2e-18 64.6 1.4 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGB08311.1 - 3.9e-10 39.7 0.2 3.9e-10 39.7 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EGB08311.1 - 2.2e-08 33.6 1.4 2.2e-08 33.6 1.4 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGB08311.1 - 1.1e-06 28.0 8.9 3.4e-06 26.4 1.9 3.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 EGB08311.1 - 5.2e-06 25.9 6.0 0.15 11.2 1.2 3.5 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB08311.1 - 2.6e-05 24.4 5.2 0.0007 19.8 0.6 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EGB08311.1 - 4.2e-05 23.0 6.8 0.0062 15.9 0.5 2.6 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EGB08311.1 - 0.00071 18.9 4.9 0.039 13.2 1.1 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EGB08311.1 - 0.00086 18.1 0.7 0.00086 18.1 0.7 3.2 3 1 1 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 EGB08311.1 - 0.0011 18.2 0.6 0.16 11.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EGB08311.1 - 0.0012 18.1 3.9 0.0021 17.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EGB08311.1 - 0.003 17.2 8.4 1 8.9 0.6 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGB08311.1 - 0.5 9.4 2.8 0.61 9.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EGB08311.1 - 1.3 9.5 5.6 3.3 8.2 0.6 3.0 3 1 0 3 3 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EGB08311.1 - 3.4 7.5 5.1 0.35 10.7 0.6 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sel1 PF08238.12 EGB08312.1 - 6.3e-17 61.6 13.5 1.8e-06 28.4 3.3 3.1 3 0 0 3 3 3 3 Sel1 repeat FA_desaturase PF00487.24 EGB08313.1 - 4.6e-15 56.1 7.4 6.9e-15 55.6 7.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGB08313.1 - 1.6e-07 31.4 0.0 4.6e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain GHD PF17834.1 EGB08313.1 - 0.0068 16.4 0.0 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase Spo7 PF03907.13 EGB08313.1 - 0.03 13.8 1.1 0.052 13.0 0.2 1.7 2 0 0 2 2 2 0 Spo7-like protein ParcG PF10274.9 EGB08314.1 - 4.7e-75 251.7 0.0 5.5e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EGB08314.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 DnaJ PF00226.31 EGB08315.1 - 4.8e-12 45.8 0.0 1.2e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Glyco_transf_41 PF13844.6 EGB08316.1 - 2.1e-126 422.1 0.0 1.6e-64 218.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EGB08316.1 - 8.2e-84 272.3 45.2 8.6e-11 41.2 0.3 13.7 14 0 0 14 14 14 12 Tetratricopeptide repeat TPR_11 PF13414.6 EGB08316.1 - 1.3e-80 264.9 36.6 3.5e-12 45.8 0.1 12.8 2 1 11 13 13 13 11 TPR repeat TPR_2 PF07719.17 EGB08316.1 - 2e-74 239.8 53.2 2.3e-08 33.5 0.2 13.8 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 EGB08316.1 - 4e-64 207.5 19.9 2.8e-06 27.1 0.0 12.3 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 EGB08316.1 - 2.5e-59 193.5 29.9 8.5e-06 25.8 0.2 12.8 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_7 PF13176.6 EGB08316.1 - 5.5e-52 170.0 32.6 1e-05 25.2 0.4 13.4 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_16 PF13432.6 EGB08316.1 - 7.7e-52 173.7 60.2 2.6e-09 37.6 0.1 8.9 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 EGB08316.1 - 1e-43 147.5 52.1 1.4e-08 34.9 2.3 9.3 4 3 6 10 10 9 9 Tetratricopeptide repeat TPR_14 PF13428.6 EGB08316.1 - 1e-40 134.9 62.7 0.00019 22.0 0.0 14.7 3 1 12 15 15 13 11 Tetratricopeptide repeat TPR_10 PF13374.6 EGB08316.1 - 2e-38 129.2 70.3 6.2e-05 22.7 0.5 14.2 15 0 0 15 15 14 9 Tetratricopeptide repeat TPR_19 PF14559.6 EGB08316.1 - 3.6e-36 123.5 35.1 2.9e-08 34.1 0.0 8.7 5 3 1 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 EGB08316.1 - 5.5e-22 76.9 13.5 0.072 13.8 0.0 11.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_4 PF07721.14 EGB08316.1 - 2.2e-15 55.6 48.9 0.17 12.6 0.7 13.5 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_15 PF13429.6 EGB08316.1 - 7.8e-14 51.6 11.7 0.00049 19.4 0.7 6.6 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGB08316.1 - 1.7e-11 44.1 41.9 0.0038 17.3 1.3 8.1 4 2 3 7 7 7 6 Tetratricopeptide repeat NARP1 PF12569.8 EGB08316.1 - 1.6e-09 37.3 1.6 0.061 12.2 0.2 4.8 3 2 0 4 4 4 3 NMDA receptor-regulated protein 1 PPR PF01535.20 EGB08316.1 - 3.8e-08 33.0 9.5 8.6 6.9 0.0 7.9 9 0 0 9 9 8 0 PPR repeat BTAD PF03704.17 EGB08316.1 - 5.1e-08 33.5 32.6 0.013 16.0 0.9 6.4 1 1 5 6 6 6 4 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EGB08316.1 - 7.9e-07 28.7 12.3 0.031 13.7 1.8 5.1 1 1 4 5 5 5 4 MalT-like TPR region FAT PF02259.23 EGB08316.1 - 4.4e-06 26.2 0.0 1.3 8.2 0.0 5.3 1 1 2 5 5 5 2 FAT domain EST1_DNA_bind PF10373.9 EGB08316.1 - 3.9e-05 23.3 16.2 0.84 9.1 0.1 6.0 4 2 1 6 6 6 1 Est1 DNA/RNA binding domain ANAPC3 PF12895.7 EGB08316.1 - 0.00064 19.9 23.5 0.037 14.3 0.0 6.3 3 1 4 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.12 EGB08316.1 - 0.001 18.9 0.1 0.4 10.4 0.0 4.2 3 3 3 6 6 6 1 Plant specific mitochondrial import receptor subunit TOM20 RPN7 PF10602.9 EGB08316.1 - 0.0054 16.5 16.9 28 4.4 0.0 7.7 3 2 7 10 10 10 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 EGB08316.1 - 0.031 14.4 1.5 24 5.1 0.1 4.2 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.9 EGB08316.1 - 0.046 13.4 15.9 3.2 7.4 1.9 5.5 1 1 3 5 5 5 0 Tetratricopeptide repeat-like domain PknG_TPR PF16918.5 EGB08316.1 - 0.12 11.1 2.7 0.26 10.0 2.7 1.4 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat DUF3856 PF12968.7 EGB08316.1 - 9.1 6.3 9.1 88 3.1 0.1 5.7 5 2 1 6 6 5 0 Domain of Unknown Function (DUF3856) LRR_8 PF13855.6 EGB08318.1 - 1.1e-16 60.4 4.7 0.0017 18.0 0.0 7.0 6 1 1 7 7 7 3 Leucine rich repeat LRR_4 PF12799.7 EGB08318.1 - 3.5e-12 46.3 4.8 0.08 13.4 0.0 7.2 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB08318.1 - 0.0032 17.8 0.1 1.9e+02 3.3 0.0 6.4 7 0 0 7 7 7 0 Leucine Rich Repeat LRRNT_2 PF08263.12 EGB08318.1 - 0.029 14.7 0.6 0.073 13.4 0.6 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain BALF1 PF06861.11 EGB08318.1 - 0.086 12.5 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 BALF1 protein LRR_6 PF13516.6 EGB08318.1 - 2.5 8.4 12.1 11 6.4 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat Ephrin_rec_like PF07699.13 EGB08318.1 - 4.2 7.2 35.2 0.37 10.6 6.2 4.7 3 1 2 5 5 5 0 Putative ephrin-receptor like NCD3G PF07562.14 EGB08318.1 - 5.6 7.0 19.8 2 8.5 1.1 4.9 4 1 1 5 5 5 0 Nine Cysteines Domain of family 3 GPCR Sigma70_r2 PF04542.14 EGB08319.1 - 2e-16 59.5 0.2 5e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EGB08319.1 - 7.3e-12 44.6 0.4 1.4e-09 37.3 0.2 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r3 PF04539.16 EGB08319.1 - 3.3e-08 33.5 0.0 1.5e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-70 region 3 HTH_10 PF04967.12 EGB08319.1 - 0.023 14.5 0.1 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain Kinesin PF00225.23 EGB08320.1 - 9.2e-89 297.6 2.8 1.1e-88 297.4 2.8 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB08320.1 - 3.4e-22 79.0 2.5 5.8e-21 75.0 0.5 2.7 3 0 0 3 3 3 1 Microtubule binding ResIII PF04851.15 EGB08320.1 - 0.027 14.5 0.4 0.084 12.9 0.1 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Pro_isomerase PF00160.21 EGB08321.1 - 5.1e-44 150.3 0.0 5.7e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 EGB08322.1 - 7.9e-18 65.2 0.0 8.9e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ion_trans PF00520.31 EGB08323.1 - 9.9e-47 159.2 24.2 1.2e-23 83.6 10.0 2.9 2 1 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 EGB08323.1 - 3.9e-05 22.5 23.1 0.00082 18.2 4.3 4.0 2 2 1 3 3 3 2 Polycystin cation channel TRAM_LAG1_CLN8 PF03798.16 EGB08323.1 - 4e-05 23.5 2.5 4e-05 23.5 2.5 2.2 2 0 0 2 2 2 1 TLC domain FAM176 PF14851.6 EGB08323.1 - 0.023 14.4 0.1 0.73 9.5 0.1 2.8 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.14 EGB08323.1 - 4.8 6.9 10.4 1.5 8.6 4.6 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 EGB08323.1 - 8.3 6.9 12.6 10 6.5 0.6 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aa_trans PF01490.18 EGB08324.1 - 4.9e-39 134.2 0.0 4.2e-21 75.1 0.0 2.2 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Fra10Ac1 PF09725.9 EGB08325.1 - 3.8e-37 127.2 0.1 4.1e-37 127.0 0.1 1.0 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Pkinase PF00069.25 EGB08326.1 - 3.7e-51 174.0 0.0 4.4e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08326.1 - 3.2e-33 115.1 0.0 3.9e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB08326.1 - 0.00025 20.0 0.0 0.00034 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Radical_SAM PF04055.21 EGB08327.1 - 2e-11 44.6 0.0 3.9e-11 43.6 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 EGB08327.1 - 2.2e-05 24.8 0.0 4.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Ald_Xan_dh_C2 PF02738.18 EGB08328.1 - 6.9e-120 401.1 4.4 1.3e-119 400.1 4.4 1.4 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase PSII_Pbs31 PF18240.1 EGB08328.1 - 1.2e-36 125.0 10.8 4.6e-36 123.1 10.8 2.1 1 0 0 1 1 1 1 Photosystem II Psb31 protein Fer2_2 PF01799.20 EGB08328.1 - 8.4e-22 77.0 0.1 2.1e-21 75.7 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 EGB08328.1 - 6.7e-20 71.5 0.1 9e-19 67.8 0.1 2.6 1 1 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EGB08328.1 - 5.9e-15 55.3 4.2 2.8e-14 53.1 4.2 2.3 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 EGB08328.1 - 0.00029 20.7 7.7 0.00096 19.1 7.7 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C PF01315.22 EGB08328.1 - 0.0035 17.7 0.3 0.0035 17.7 0.3 2.1 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Ank_2 PF12796.7 EGB08329.1 - 6.3e-17 61.9 0.1 6e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08329.1 - 9.5e-17 61.1 2.7 4.7e-10 39.8 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08329.1 - 1.6e-15 55.6 0.4 8.3e-05 22.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB08329.1 - 9.8e-15 54.4 1.3 4.3e-07 30.1 0.0 3.6 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB08329.1 - 1.4e-13 50.6 0.7 0.00076 19.8 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat DUF4568 PF15132.6 EGB08329.1 - 0.16 11.4 0.4 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4568) Ank_2 PF12796.7 EGB08330.1 - 2.7e-16 59.9 1.1 1.9e-10 41.2 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08330.1 - 1.9e-13 50.6 0.3 2.6e-06 27.8 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB08330.1 - 7.2e-10 38.9 8.4 1.2e-06 28.7 0.4 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB08330.1 - 2.4e-09 36.6 1.3 3.2e-05 24.0 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB08330.1 - 3.4e-08 33.6 5.7 0.00028 21.1 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Peptidase_C65 PF10275.9 EGB08331.1 - 1e-23 84.0 0.0 1.3e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain LRR_6 PF13516.6 EGB08332.1 - 7.8e-13 47.4 8.9 0.48 10.6 0.0 9.0 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 EGB08332.1 - 0.0056 17.1 0.2 38 4.9 0.0 4.2 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) FlxA PF14282.6 EGB08332.1 - 0.027 14.5 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF3197 PF11432.8 EGB08332.1 - 3.9 7.4 7.0 15 5.5 1.4 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3197) Enolase_C PF00113.22 EGB08333.1 - 1.4e-43 149.3 0.0 1.9e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGB08333.1 - 2.5e-17 63.3 0.6 3.3e-16 59.6 0.6 2.4 1 1 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.11 EGB08333.1 - 0.0054 15.9 0.0 0.027 13.6 0.0 2.0 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Fea1 PF07692.11 EGB08334.1 - 9.8e-46 156.4 2.4 5.5e-22 78.3 0.4 2.4 1 1 1 2 2 2 2 Low iron-inducible periplasmic protein DUF4537 PF15057.6 EGB08334.1 - 9.4e-28 96.7 15.5 0.0001 22.3 0.0 7.5 7 0 0 7 7 7 5 Domain of unknown function (DUF4537) DUF1325 PF07039.11 EGB08334.1 - 4.4e-22 78.6 0.1 0.0014 18.7 0.0 8.2 8 0 0 8 8 8 5 SGF29 tudor-like domain Asp_Arg_Hydrox PF05118.15 EGB08334.1 - 6.9e-21 74.7 0.0 1.5e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Tudor_3 PF18115.1 EGB08334.1 - 4.1e-17 61.8 32.6 7.3e-06 25.7 0.3 11.7 13 0 0 13 13 13 4 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 EGB08334.1 - 4.7e-10 39.0 36.2 0.0011 18.6 0.1 8.9 9 0 0 9 9 9 4 Histone methyltransferase Tudor domain 1 53-BP1_Tudor PF09038.10 EGB08334.1 - 2e-08 34.2 13.1 0.03 14.3 0.0 7.7 9 0 0 9 9 9 2 Tumour suppressor p53-binding protein-1 Tudor Agenet PF05641.12 EGB08334.1 - 4.6e-08 33.4 10.7 3.1 8.3 0.0 9.7 11 0 0 11 11 11 1 Agenet domain TMEM154 PF15102.6 EGB08334.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Tudor_2 PF18104.1 EGB08334.1 - 0.027 14.2 21.0 0.91 9.3 0.2 8.2 10 0 0 10 10 10 0 Jumonji domain-containing protein 2A Tudor domain BPL_LplA_LipB PF03099.19 EGB08335.1 - 3.1e-12 46.5 0.0 4.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_LplA_LipB_2 PF16917.5 EGB08335.1 - 0.00033 20.3 0.3 0.00057 19.5 0.3 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3158 PF11358.8 EGB08335.1 - 0.018 14.8 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) Mobilization_B PF17511.2 EGB08335.1 - 5.4 7.4 6.4 0.83 10.0 2.4 1.6 2 0 0 2 2 2 0 Mobilization protein B DnaJ PF00226.31 EGB08336.1 - 7.1e-17 61.3 0.1 1e-16 60.8 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Evr1_Alr PF04777.13 EGB08337.1 - 4e-24 85.0 0.0 4.5e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Erv1 / Alr family Glyco_transf_25 PF01755.17 EGB08338.1 - 7.3e-20 71.7 0.0 2e-18 67.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) adh_short PF00106.25 EGB08339.1 - 2.9e-21 75.8 0.0 4.8e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB08339.1 - 9.2e-16 58.1 0.0 3.1e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB08339.1 - 2.1e-10 40.8 0.1 3.1e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGB08339.1 - 0.0028 17.6 0.1 0.0079 16.1 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGB08339.1 - 0.12 11.8 0.1 0.52 9.7 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 EGB08339.1 - 0.15 11.9 0.6 0.26 11.2 0.6 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus RCC1 PF00415.18 EGB08340.1 - 6.3e-39 132.4 20.1 4.5e-13 49.6 1.2 5.3 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB08340.1 - 1.8e-30 104.1 21.2 1.1e-09 37.8 0.7 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat TP_methylase PF00590.20 EGB08341.1 - 4.8e-25 88.8 5.0 2.3e-24 86.5 5.0 2.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF563 PF04577.14 EGB08341.1 - 1.1e-22 81.2 0.0 2.1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Peptidase_U32 PF01136.19 EGB08342.1 - 9e-88 293.3 0.0 4.1e-75 251.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family U32 DUF3656 PF12392.8 EGB08342.1 - 1.4e-14 54.6 0.0 2.6e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Collagenase TylF PF05711.11 EGB08343.1 - 6.1e-22 78.1 0.0 1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EGB08343.1 - 1e-12 49.0 0.0 4.6e-12 46.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Sulfotransfer_3 PF13469.6 EGB08343.1 - 2.5e-07 31.3 0.0 0.0098 16.3 0.0 2.5 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB08343.1 - 0.0024 17.4 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain PEP-utilisers_N PF05524.13 EGB08343.1 - 0.38 10.9 3.1 0.21 11.8 0.2 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF5585 PF17823.1 EGB08344.1 - 0.17 10.8 1.4 0.28 10.1 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Sec1 PF00995.23 EGB08345.1 - 5e-17 62.4 0.0 5.3e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chloroa_b-bind PF00504.21 EGB08346.1 - 1.3e-30 107.0 0.1 1.7e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2781 PF10914.8 EGB08347.1 - 0.00085 19.8 2.7 0.0013 19.1 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Cyclin_N PF00134.23 EGB08348.1 - 1e-24 86.7 0.0 1.7e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGB08348.1 - 0.0036 17.4 0.0 0.31 11.1 0.0 2.5 2 0 0 2 2 2 2 Cyclin, C-terminal domain Complex1_LYR PF05347.15 EGB08349.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.3 1 1 0 1 1 1 1 Complex 1 protein (LYR family) TcpS PF17456.2 EGB08349.1 - 0.098 12.7 0.0 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S Kelch_4 PF13418.6 EGB08350.1 - 2.4e-26 91.5 13.5 1.7e-07 31.1 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGB08350.1 - 4.8e-26 90.5 17.4 3.6e-06 27.1 0.3 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EGB08350.1 - 9.1e-25 86.0 3.2 1.7e-07 30.7 0.0 5.3 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EGB08350.1 - 7.8e-23 80.0 0.3 3.2e-07 30.4 0.0 6.4 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGB08350.1 - 4.8e-18 64.4 2.1 6.4e-06 25.9 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EGB08350.1 - 9.4e-18 63.8 3.3 9.6e-05 22.3 0.0 6.5 6 0 0 6 6 6 5 Kelch motif CYYR1 PF10873.8 EGB08350.1 - 0.0015 19.0 9.2 0.0015 19.0 9.2 2.1 3 0 0 3 3 3 1 Cysteine and tyrosine-rich protein 1 Tyrosinase PF00264.20 EGB08351.1 - 1.2e-19 71.5 0.0 2e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase DOPA_dioxygen PF08883.11 EGB08351.1 - 0.011 15.8 0.0 0.03 14.5 0.0 1.7 1 1 0 1 1 1 0 Dopa 4,5-dioxygenase family HAD_2 PF13419.6 EGB08352.1 - 4.5e-10 39.9 0.0 7.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB08352.1 - 0.0016 18.8 0.0 0.002 18.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB08352.1 - 0.0045 17.0 0.1 0.008 16.2 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGB08352.1 - 0.015 15.7 0.1 0.029 14.8 0.0 1.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Melibiase_2_C PF17450.2 EGB08352.1 - 0.19 12.0 0.0 0.78 10.0 0.0 1.9 2 1 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain Thioredoxin PF00085.20 EGB08353.1 - 6.7e-21 74.2 0.2 2.5e-20 72.4 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB08353.1 - 0.00032 21.1 0.1 0.00092 19.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.10 EGB08353.1 - 0.014 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 EGB08353.1 - 0.016 15.6 0.1 0.065 13.6 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 EGB08353.1 - 0.071 13.3 0.1 0.071 13.3 0.1 2.3 3 0 0 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 EGB08353.1 - 0.13 12.2 0.2 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA family GCD14 PF08704.10 EGB08353.1 - 0.15 11.8 0.1 0.33 10.6 0.1 1.6 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit GCP_C_terminal PF04130.13 EGB08353.1 - 0.15 11.5 0.1 0.99 8.8 0.3 1.8 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal Glutaredoxin PF00462.24 EGB08353.1 - 0.17 12.2 0.1 0.54 10.5 0.1 1.9 2 0 0 2 2 2 0 Glutaredoxin PH PF00169.29 EGB08354.1 - 7.4e-08 32.9 0.0 1.3e-06 28.8 0.0 3.0 3 0 0 3 3 3 1 PH domain PDZ_6 PF17820.1 EGB08354.1 - 0.0002 21.1 0.0 0.00051 19.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PRT_C PF08372.10 EGB08354.1 - 0.00027 20.7 0.1 0.00051 19.8 0.1 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal PH_11 PF15413.6 EGB08354.1 - 0.0051 17.2 0.0 1.4 9.4 0.0 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain DUF639 PF04842.12 EGB08354.1 - 0.078 12.4 0.0 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) tRNA_U5-meth_tr PF05958.11 EGB08355.1 - 3.8e-19 68.9 0.0 6.7e-18 64.8 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 EGB08355.1 - 4.4e-08 33.0 0.1 9.2e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_25 PF13649.6 EGB08355.1 - 3.3e-05 24.5 0.3 9.7e-05 23.0 0.3 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGB08355.1 - 8.7e-05 22.2 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EGB08355.1 - 0.00072 20.2 0.2 0.0036 17.9 0.2 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB08355.1 - 0.0019 18.0 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB08355.1 - 0.0019 17.7 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EGB08355.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.13 EGB08355.1 - 0.068 12.6 0.9 0.1 12.0 0.9 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 EGB08355.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Metallophos PF00149.28 EGB08356.1 - 2.1e-20 74.1 1.0 2.7e-20 73.8 1.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Transket_pyr PF02779.24 EGB08357.1 - 1.5e-41 142.1 0.0 2.3e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGB08357.1 - 4.6e-34 117.0 0.1 7.5e-34 116.3 0.1 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EGB08357.1 - 0.092 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II ABC2_membrane PF01061.24 EGB08358.1 - 7.6e-28 97.4 1.4 7.6e-28 97.4 1.4 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGB08358.1 - 1.2e-23 84.1 0.0 1.9e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB08358.1 - 4.2e-05 23.5 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGB08358.1 - 6.2e-05 22.3 0.8 8.8e-05 21.8 0.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGB08358.1 - 0.0087 15.8 0.3 0.02 14.7 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB08358.1 - 0.0098 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EGB08358.1 - 0.014 14.9 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB08358.1 - 0.22 11.4 0.2 1.1 9.1 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 EGB08358.1 - 0.25 11.7 3.2 0.13 12.7 0.4 2.1 2 1 0 2 2 2 0 AAA ATPase domain Abhydrolase_2 PF02230.16 EGB08359.1 - 2.5e-06 27.5 0.0 4.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 EGB08359.1 - 0.0011 17.7 0.1 0.0019 17.0 0.1 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 EGB08359.1 - 0.0017 18.0 0.1 0.0049 16.5 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 EGB08359.1 - 0.0022 17.5 0.0 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGB08359.1 - 0.0087 15.4 1.5 0.02 14.1 0.1 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 EGB08359.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cupin_8 PF13621.6 EGB08361.1 - 5.7e-13 49.2 0.0 9.6e-12 45.2 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGB08361.1 - 4.6e-11 43.1 0.5 0.0003 21.2 0.0 2.2 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGB08361.1 - 3.1e-05 23.6 0.5 7.9e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB08361.1 - 0.035 13.8 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 EGB08361.1 - 0.065 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Cupin MFS_1 PF07690.16 EGB08362.1 - 1.3e-24 86.8 7.1 1.3e-24 86.8 7.1 4.2 4 2 0 4 4 4 1 Major Facilitator Superfamily ERCC4 PF02732.15 EGB08362.1 - 8.4e-08 32.6 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain SAP PF02037.27 EGB08362.1 - 0.00023 20.8 0.6 0.00044 19.9 0.6 1.5 1 0 0 1 1 1 1 SAP domain 2OG-FeII_Oxy_3 PF13640.6 EGB08363.1 - 1.7e-11 44.8 0.0 2.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB08363.1 - 0.0017 18.8 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2877 PF11392.8 EGB08363.1 - 0.071 13.8 5.9 1.5e+02 3.1 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2877) DUF3237 PF11578.8 EGB08363.1 - 0.46 10.3 1.4 18 5.2 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3237) DUF4444 PF14563.6 EGB08363.1 - 4.9 6.9 9.3 1.4e+02 2.3 0.1 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4444) DUF2877 PF11392.8 EGB08364.1 - 0.036 14.8 8.0 92 3.8 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2877) DUF4444 PF14563.6 EGB08364.1 - 0.28 10.9 12.1 87 2.9 0.1 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4444) ABC_tran PF00005.27 EGB08365.1 - 1.9e-35 122.3 0.0 4.6e-16 59.6 0.0 3.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EGB08365.1 - 3.7e-24 85.3 14.5 2.1e-16 60.0 0.6 3.7 4 0 0 4 4 4 2 ABC-2 type transporter AAA_29 PF13555.6 EGB08365.1 - 5.3e-06 26.1 0.5 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB08365.1 - 9.3e-06 25.7 0.5 0.92 9.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB08365.1 - 4.7e-05 23.4 0.3 0.25 11.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 EGB08365.1 - 0.0027 17.6 0.2 2.1 8.2 0.1 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 EGB08365.1 - 0.0033 17.5 0.3 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EGB08365.1 - 0.013 16.0 0.6 10 6.7 0.2 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGB08365.1 - 0.83 9.7 2.4 10 6.2 0.5 2.4 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 EGB08365.1 - 3.6 7.9 6.1 30 4.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain CH PF00307.31 EGB08366.1 - 1.8e-17 63.5 0.0 2.8e-08 33.9 0.0 3.6 4 0 0 4 4 4 2 Calponin homology (CH) domain Pkinase PF00069.25 EGB08367.1 - 1.3e-37 129.7 0.0 1.7e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08367.1 - 2.7e-20 72.7 0.0 3.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase 2OG-FeII_Oxy_3 PF13640.6 EGB08367.1 - 1.7e-14 54.5 0.0 6.9e-12 46.1 0.0 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB08367.1 - 1.9e-10 41.2 0.0 0.00086 19.9 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Hormone_2 PF00123.20 EGB08367.1 - 0.033 14.1 0.2 0.085 12.8 0.2 1.7 1 0 0 1 1 1 0 Peptide hormone Kinase-like PF14531.6 EGB08367.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Myb_DNA-binding PF00249.31 EGB08368.1 - 4.9e-46 154.7 10.3 1.3e-15 57.3 0.4 3.0 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB08368.1 - 2.1e-39 133.6 2.0 5.9e-14 52.1 0.0 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB08368.1 - 4.8e-05 23.2 0.2 0.00073 19.4 0.0 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EGB08368.1 - 5.6e-05 23.1 4.5 0.047 13.8 0.2 3.1 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EGB08368.1 - 0.00053 20.0 0.0 4.7 7.3 0.0 3.1 1 1 2 3 3 3 2 SLIDE MADF_DNA_bdg PF10545.9 EGB08368.1 - 0.0015 18.8 2.1 8.5 6.8 0.1 3.2 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Atg29_N PF18388.1 EGB08368.1 - 0.013 15.3 2.2 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Atg29 N-terminal domain SANT_DAMP1_like PF16282.5 EGB08368.1 - 0.029 14.6 0.6 2.8 8.2 0.0 3.0 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Death PF00531.22 EGB08368.1 - 0.095 12.9 0.2 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 Death domain Sigma70_r4_2 PF08281.12 EGB08368.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 O-FucT PF10250.9 EGB08369.1 - 3.9e-14 53.1 1.4 1.7e-09 37.9 0.2 3.0 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Methyltransf_24 PF13578.6 EGB08369.1 - 0.00022 22.2 0.1 0.0006 20.8 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.25 EGB08370.1 - 1e-37 130.0 0.0 1.2e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08370.1 - 1.8e-21 76.6 0.0 1.9e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB08370.1 - 0.00012 21.0 0.0 0.00014 20.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB08370.1 - 0.0015 18.5 0.6 0.0045 16.9 0.4 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB08370.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB08370.1 - 0.014 14.8 0.2 0.022 14.1 0.1 1.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tyrosinase PF00264.20 EGB08371.1 - 3.7e-09 37.2 1.6 1.6e-06 28.5 0.1 2.6 3 0 0 3 3 3 2 Common central domain of tyrosinase Terminase_6C PF17289.2 EGB08371.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Terminase RNaseH-like domain PseudoU_synth_2 PF00849.22 EGB08372.1 - 2.5e-08 34.1 0.0 3.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Homoserine_dh PF00742.19 EGB08373.1 - 6.2e-52 176.0 0.1 9e-52 175.5 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGB08373.1 - 1.6e-12 48.1 0.7 3.2e-12 47.1 0.7 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 EGB08373.1 - 0.011 15.5 0.1 0.034 13.9 0.0 1.9 2 0 0 2 2 2 0 ACT domain EF-hand_6 PF13405.6 EGB08374.1 - 1.1e-08 34.4 0.0 0.084 12.9 0.0 5.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 EGB08374.1 - 0.00023 20.5 0.1 3.7 7.3 0.0 5.0 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 EGB08374.1 - 0.0048 17.3 0.0 8.9 6.9 0.0 3.6 2 1 2 4 4 4 3 EF-hand domain pair Rcd1 PF04078.13 EGB08375.1 - 1.4e-126 421.1 0.6 1.6e-126 420.9 0.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like IncF PF17626.2 EGB08376.1 - 0.22 11.9 4.9 0.18 12.2 0.9 2.3 2 0 0 2 2 2 0 Inclusion membrane protein F Pellino PF04710.14 EGB08377.1 - 7.8e-75 252.1 0.0 4.6e-71 239.7 0.0 3.1 1 1 0 1 1 1 1 Pellino zf-RING_2 PF13639.6 EGB08377.1 - 0.062 13.7 2.8 8 6.9 0.2 3.0 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 EGB08377.1 - 0.093 12.6 5.7 1.9 8.4 1.1 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGB08377.1 - 0.1 12.4 5.1 8.8 6.3 0.2 3.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB08377.1 - 0.25 11.4 0.7 6 6.9 0.0 2.9 2 1 0 2 2 2 0 zinc-RING finger domain Acyl_transf_3 PF01757.22 EGB08378.1 - 5.1e-12 45.5 8.0 6.7e-12 45.1 8.0 1.1 1 0 0 1 1 1 1 Acyltransferase family RSN1_TM PF13967.6 EGB08378.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport FKBP_C PF00254.28 EGB08379.1 - 1.2e-23 83.2 0.1 2.5e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Borrelia_P83 PF05262.11 EGB08379.1 - 8.5 4.7 8.2 13 4.2 8.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FAM221 PF14753.6 EGB08380.1 - 1.5e-44 151.9 6.2 1.7e-44 151.8 6.2 1.0 1 0 0 1 1 1 1 Protein FAM221A/B Na_Ca_ex PF01699.24 EGB08381.1 - 4.4e-41 140.3 31.3 9.2e-21 74.4 10.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_1 PF00036.32 EGB08381.1 - 4.9e-08 32.0 0.7 0.0041 16.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB08381.1 - 1e-07 32.3 1.4 1.7e-07 31.6 1.4 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB08381.1 - 4.1e-07 29.4 2.1 0.00025 20.7 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB08381.1 - 1.4e-05 24.8 1.3 2.9e-05 23.8 0.4 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB08381.1 - 1.6e-05 24.1 1.3 0.0039 16.6 0.1 2.4 2 0 0 2 2 2 2 EF hand TPR_15 PF13429.6 EGB08381.1 - 0.0025 17.1 0.0 0.0035 16.6 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat tRNA-synt_2b PF00587.25 EGB08382.1 - 4.3e-25 88.7 0.0 1.1e-24 87.4 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGB08382.1 - 2e-15 56.9 1.0 3.1e-15 56.3 1.0 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain tRNA_bind_4 PF18490.1 EGB08382.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 tRNA-binding domain HIP1_clath_bdg PF16515.5 EGB08382.1 - 0.85 10.3 3.7 1.4 9.6 3.7 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sulfatase PF00884.23 EGB08383.1 - 1.3e-31 110.2 0.0 1.4e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase SRCR PF00530.18 EGB08384.1 - 1.7e-48 163.2 37.5 2.1e-16 60.2 0.1 5.0 5 0 0 5 5 5 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EGB08384.1 - 4.7e-07 30.3 18.5 0.31 11.6 0.0 4.8 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Herpes_LMP1 PF05297.11 EGB08384.1 - 0.43 9.7 9.3 1 8.5 9.3 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Kelch_6 PF13964.6 EGB08384.1 - 0.91 9.9 4.3 30 5.1 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Kunitz_BPTI PF00014.23 EGB08384.1 - 1.6 9.0 19.3 0.73 10.1 2.5 4.0 3 0 0 3 3 3 0 Kunitz/Bovine pancreatic trypsin inhibitor domain ABC_tran PF00005.27 EGB08385.1 - 1.3e-10 41.9 0.0 3.9e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGB08385.1 - 0.00072 19.2 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB08385.1 - 0.0052 16.6 1.8 0.016 15.0 1.3 1.9 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 EGB08385.1 - 0.056 13.1 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EGB08385.1 - 0.07 13.6 0.4 0.72 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB08385.1 - 0.082 13.4 0.1 0.32 11.5 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB08385.1 - 0.18 12.1 0.0 0.18 12.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EGB08385.1 - 0.22 11.9 0.0 0.22 11.9 0.0 4.4 4 1 0 4 4 3 0 AAA ATPase domain AAA_14 PF13173.6 EGB08385.1 - 0.23 11.5 0.0 0.46 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB08385.1 - 0.54 10.1 2.2 0.74 9.7 0.1 2.3 3 0 0 3 3 3 0 NACHT domain APG6_N PF17675.1 EGB08385.1 - 5.6 7.5 7.7 1.8 9.1 3.7 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Ribonuclease_T2 PF00445.18 EGB08386.1 - 4e-07 30.5 0.0 5.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family TIL PF01826.17 EGB08387.1 - 3.3e-05 24.0 9.8 3.3e-05 24.0 9.8 4.6 2 2 1 4 4 4 2 Trypsin Inhibitor like cysteine rich domain GFA PF04828.14 EGB08388.1 - 2.7e-07 30.8 0.6 2.7e-07 30.8 0.6 1.8 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 EGB08388.1 - 0.021 15.0 0.1 0.021 15.0 0.1 2.4 3 0 0 3 3 3 0 Ribosomal protein L37e DUF5447 PF17525.2 EGB08388.1 - 5.6 7.5 7.1 2.5 8.6 1.4 2.6 1 1 0 1 1 1 0 Family of unknown function (DUF5447) MFS_1 PF07690.16 EGB08389.1 - 1e-17 64.2 41.0 1e-17 64.2 41.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Rieske PF00355.26 EGB08389.1 - 0.0053 16.7 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF2635 PF10948.8 EGB08389.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) MM_CoA_mutase PF01642.22 EGB08390.1 - 9.3e-209 694.2 0.2 1.2e-208 693.8 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 EGB08390.1 - 1.7e-15 57.1 3.0 1.7e-15 57.1 3.0 2.0 2 0 0 2 2 2 1 B12 binding domain EF-hand_7 PF13499.6 EGB08391.1 - 5.5e-25 87.6 1.9 6.1e-14 52.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB08391.1 - 6.3e-24 81.7 11.2 5.7e-08 31.8 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB08391.1 - 4.2e-20 69.9 7.4 2e-07 30.4 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB08391.1 - 2.6e-11 43.2 9.9 3.4e-05 23.6 0.7 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB08391.1 - 2.3e-08 33.2 7.3 0.0017 17.8 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 EGB08391.1 - 8.8e-05 22.4 0.3 0.026 14.5 0.1 2.5 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGB08391.1 - 0.00063 20.0 0.1 0.45 10.9 0.0 2.5 2 1 1 3 3 3 3 EF-hand domain EF-hand_11 PF08976.11 EGB08391.1 - 0.024 15.5 0.0 1.8 9.5 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain p25-alpha PF05517.12 EGB08391.1 - 0.054 13.7 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 p25-alpha Myb_DNA-binding PF00249.31 EGB08392.1 - 8e-30 102.8 7.3 7.7e-17 61.2 0.5 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB08392.1 - 6.1e-25 87.3 6.8 1e-15 57.7 1.6 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB08392.1 - 0.001 18.9 0.1 0.0036 17.2 0.0 1.9 1 1 1 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EGB08392.1 - 0.0011 19.2 2.4 0.047 14.0 0.2 2.2 1 1 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 EGB08392.1 - 0.0062 16.6 0.1 0.072 13.1 0.0 2.1 1 1 1 2 2 2 1 SLIDE Sigma70_r4_2 PF08281.12 EGB08392.1 - 0.057 13.1 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 DUF2448 PF10476.9 EGB08392.1 - 0.16 11.8 0.4 4 7.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Ysc84 PF04366.12 EGB08393.1 - 3.2e-28 98.1 0.8 5.6e-28 97.2 0.8 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 EGB08393.1 - 1.1e-14 54.3 3.6 1.7e-14 53.7 3.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGB08393.1 - 1.4 9.2 4.4 3.5 7.9 4.2 1.6 1 1 1 2 2 2 0 FYVE-type zinc finger zf-PARP PF00645.18 EGB08394.1 - 1.7e-06 28.8 0.0 2.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region GST_N_2 PF13409.6 EGB08395.1 - 1.8e-14 53.8 0.0 4.8e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB08395.1 - 2.3e-09 37.5 0.0 4.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGB08395.1 - 2.9e-08 33.9 0.0 5.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB08395.1 - 0.00024 21.0 0.3 0.00024 21.0 0.3 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB08395.1 - 0.0074 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGB08395.1 - 0.042 14.1 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin His_Phos_1 PF00300.22 EGB08396.1 - 1.1e-29 103.6 4.5 4.2e-22 78.8 2.1 3.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF1726 PF08351.11 EGB08396.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) Glyco_hydro_28 PF00295.17 EGB08397.1 - 2.1e-20 73.1 0.0 3.6e-20 72.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EGB08397.1 - 5.8e-08 32.8 0.0 1.3e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.6 EGB08397.1 - 0.0011 18.9 0.1 0.0024 17.8 0.1 1.6 1 1 0 1 1 1 1 Right handed beta helix region DUF295 PF03478.18 EGB08397.1 - 0.011 15.3 0.1 0.034 13.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF295) ADH_N_2 PF16884.5 EGB08398.1 - 7.7e-18 64.4 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGB08398.1 - 1.9e-17 63.5 0.1 3.4e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGB08398.1 - 0.0026 18.8 0.0 0.015 16.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGB08398.1 - 0.049 13.0 0.1 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EGB08398.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TMEM65 PF10507.9 EGB08399.1 - 1.9e-21 76.0 4.1 2.2e-21 75.8 4.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 65 PAP_assoc PF03828.19 EGB08400.1 - 0.00036 20.7 0.0 0.00083 19.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGB08400.1 - 0.00043 20.5 0.1 0.00086 19.5 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain OTU PF02338.19 EGB08401.1 - 3.1e-10 40.6 0.0 3.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGB08401.1 - 0.0012 18.4 1.1 0.011 15.2 1.1 1.9 1 1 1 2 2 2 2 Peptidase C65 Otubain Putative_PNPOx PF01243.20 EGB08402.1 - 1.4e-21 76.5 0.2 1.5e-20 73.2 0.1 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EGB08402.1 - 2.1e-19 69.3 0.8 4.2e-19 68.4 0.8 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 EGB08402.1 - 1.4e-07 32.0 0.0 2.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PRiA4_ORF3 PF07929.11 EGB08403.1 - 1.5e-21 76.8 0.0 2.5e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 EGB08403.1 - 7.9e-11 41.9 12.6 2.1e-10 40.5 12.6 1.8 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 EGB08403.1 - 9.8e-09 35.7 0.0 2.6e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Kelch_4 PF13418.6 EGB08403.1 - 4.4e-07 29.8 0.3 1.4 8.9 0.0 5.5 6 0 0 6 6 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EGB08403.1 - 6.7e-07 29.5 3.2 0.15 12.4 0.0 6.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EGB08403.1 - 2.7e-06 27.4 0.6 0.081 13.2 0.0 4.8 5 0 0 5 5 4 1 Kelch motif Kelch_1 PF01344.25 EGB08403.1 - 4.6e-06 26.1 4.7 0.03 13.9 0.2 5.1 5 0 0 5 5 5 1 Kelch motif Ank_3 PF13606.6 EGB08403.1 - 0.00011 22.4 0.2 0.52 11.0 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGB08403.1 - 0.00056 20.4 0.3 0.023 15.3 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB08403.1 - 0.00089 19.6 3.5 0.33 11.5 0.0 4.0 5 0 0 5 5 4 1 Ankyrin repeat Ank_5 PF13857.6 EGB08403.1 - 0.0013 19.0 2.6 0.96 9.9 0.0 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) zf-Mss51 PF13824.6 EGB08403.1 - 0.025 14.7 4.1 0.079 13.1 4.1 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Kelch_5 PF13854.6 EGB08403.1 - 0.032 14.2 0.5 0.22 11.5 0.1 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 EGB08403.1 - 0.11 12.5 1.7 3.6 7.7 0.1 4.2 6 0 0 6 6 5 0 Kelch motif zf-HIT PF04438.16 EGB08403.1 - 1 9.3 5.1 2.3 8.1 5.1 1.6 1 0 0 1 1 1 0 HIT zinc finger Dynein_light PF01221.18 EGB08404.1 - 2.1e-19 69.6 0.3 2.2e-19 69.6 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 EGB08404.1 - 0.0016 19.0 0.0 0.0017 19.0 0.0 1.1 1 0 0 1 1 1 1 Ground-like domain p450 PF00067.22 EGB08405.1 - 1.8e-63 214.9 0.0 2.5e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peripla_BP_4 PF13407.6 EGB08405.1 - 7.4e-15 55.2 17.5 4e-12 46.3 15.1 2.3 2 0 0 2 2 2 2 Periplasmic binding protein domain CAP_N PF01213.19 EGB08405.1 - 6.8 6.1 7.6 0.43 10.0 2.0 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DnaJ PF00226.31 EGB08406.1 - 1.2e-21 76.6 2.3 1.4e-21 76.4 2.3 1.1 1 0 0 1 1 1 1 DnaJ domain EF-hand_8 PF13833.6 EGB08407.1 - 0.0008 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB08407.1 - 0.0055 16.5 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EGB08407.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EGB08407.1 - 0.034 13.7 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 EF hand Rhomboid PF01694.22 EGB08408.1 - 1e-16 61.3 2.3 1.9e-16 60.4 2.3 1.4 1 0 0 1 1 1 1 Rhomboid family EF-hand_7 PF13499.6 EGB08408.1 - 2.8e-06 27.7 0.0 0.12 12.8 0.0 4.6 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_8 PF13833.6 EGB08408.1 - 9.3e-06 25.4 0.0 0.32 10.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB08408.1 - 9.1e-05 22.1 0.0 0.039 13.9 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain Peptidase_S9 PF00326.21 EGB08408.1 - 0.00042 19.9 0.1 0.00087 18.8 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family EF-hand_1 PF00036.32 EGB08408.1 - 0.0019 17.6 0.4 0.013 15.0 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 EGB08408.1 - 0.0044 16.5 0.0 0.014 14.9 0.0 1.9 1 0 0 1 1 1 1 EF hand Esterase PF00756.20 EGB08408.1 - 0.015 14.9 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 EGB08408.1 - 0.044 13.4 0.1 0.095 12.3 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold TYW3 PF02676.14 EGB08410.1 - 3.5e-35 121.3 0.0 3.9e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1254 PF06863.12 EGB08410.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) Hydrolase_6 PF13344.6 EGB08411.1 - 2.6e-25 88.5 0.0 4.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB08411.1 - 1.2e-11 44.5 0.2 1.2e-11 44.5 0.2 2.2 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 EGB08411.1 - 1.4e-06 28.8 4.3 4.3e-06 27.2 4.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGB08411.1 - 0.00015 21.9 0.0 0.0067 16.5 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGB08411.1 - 0.0061 16.2 0.0 0.022 14.4 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Transglut_core3 PF13471.6 EGB08411.1 - 0.87 9.5 6.8 0.11 12.4 1.4 2.2 2 2 0 2 2 2 0 Transglutaminase-like superfamily SNF2_N PF00176.23 EGB08412.1 - 1.7e-38 132.2 0.0 4.2e-37 127.7 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain zf-CW PF07496.15 EGB08412.1 - 2.3e-08 33.9 7.1 5e-08 32.8 7.1 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger Helicase_C PF00271.31 EGB08412.1 - 1.9e-06 28.2 0.0 4.7e-06 26.9 0.0 1.7 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EGB08412.1 - 0.00024 21.0 2.2 0.00024 21.0 2.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain ResIII PF04851.15 EGB08412.1 - 0.00043 20.3 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 EGB08412.1 - 0.15 12.3 0.6 0.34 11.1 0.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGB08412.1 - 0.82 9.6 11.2 0.062 13.2 4.2 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB08412.1 - 2.5 8.0 7.3 0.14 12.0 1.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB08412.1 - 2.6 8.4 6.6 0.43 11.0 2.4 1.9 2 0 0 2 2 1 0 Ring finger domain Prok-RING_4 PF14447.6 EGB08412.1 - 4.6 7.2 8.0 2.8 7.9 5.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGB08412.1 - 9.4 6.2 5.9 1.9 8.4 1.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 EGB08413.1 - 0.002 18.4 0.1 0.007 16.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) UIM PF02809.20 EGB08413.1 - 0.008 16.0 21.0 0.012 15.5 3.7 4.3 3 0 0 3 3 3 2 Ubiquitin interaction motif 2OG-FeII_Oxy_3 PF13640.6 EGB08413.1 - 0.03 15.2 0.0 0.075 13.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 EGB08414.1 - 1.2e-26 93.9 0.0 1.7e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB08414.1 - 0.0003 20.7 0.8 0.0049 16.8 0.9 2.2 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGB08414.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGB08414.1 - 0.0032 16.8 0.2 0.0058 15.9 0.2 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 EGB08414.1 - 0.011 16.1 0.1 0.48 10.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB08414.1 - 0.024 14.9 0.3 0.05 13.9 0.3 1.7 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EGB08414.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 EGB08414.1 - 0.036 14.2 1.0 0.086 12.9 1.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EGB08414.1 - 0.038 13.7 1.5 0.092 12.5 1.0 1.8 1 1 1 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGB08414.1 - 0.054 13.2 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGB08414.1 - 0.073 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_21 PF13304.6 EGB08414.1 - 0.073 12.9 1.9 2 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGB08414.1 - 0.13 12.7 2.7 0.11 13.0 1.1 1.7 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EGB08414.1 - 0.19 11.5 0.6 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Thioredoxin PF00085.20 EGB08415.1 - 9.9e-26 89.7 0.0 1.4e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.12 EGB08415.1 - 3.2e-06 27.9 0.0 5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain TMEM206 PF15122.6 EGB08415.1 - 0.044 12.9 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 TMEM206 protein family Thioredoxin_2 PF13098.6 EGB08415.1 - 0.092 13.2 0.0 0.31 11.5 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGB08415.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Glyco_hydro_32N PF00251.20 EGB08416.1 - 3.5e-17 62.9 0.0 3.7e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32N PF00251.20 EGB08417.1 - 6.1e-22 78.6 0.0 1.2e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_11 PF08241.12 EGB08417.1 - 1.6e-12 47.9 0.0 3.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB08417.1 - 1.8e-12 47.8 0.0 3.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB08417.1 - 5.5e-08 32.4 0.0 1.2e-07 31.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGB08417.1 - 6.3e-08 32.6 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB08417.1 - 5.9e-07 30.1 0.0 1.2e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_32C PF08244.12 EGB08417.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Methyltransf_23 PF13489.6 EGB08417.1 - 0.0046 16.8 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Myosin_head PF00063.21 EGB08418.1 - 3.9e-69 233.6 0.0 4.4e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB08418.1 - 0.0042 17.5 0.0 0.0061 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGB08418.1 - 0.027 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 EGB08418.1 - 0.049 13.3 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 EGB08418.1 - 0.056 13.7 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB08418.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EGB08418.1 - 0.26 10.6 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 KaiC Myosin_head PF00063.21 EGB08419.1 - 1e-70 238.8 0.0 1.3e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CBS PF00571.28 EGB08420.1 - 4.2e-19 68.7 5.0 8e-06 26.2 0.0 4.3 4 0 0 4 4 4 4 CBS domain Pox_Ag35 PF03286.14 EGB08421.1 - 1.2 8.9 11.4 4.2 7.1 2.0 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nop53 PF07767.11 EGB08421.1 - 2.2 7.6 9.4 6.2 6.1 1.5 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PapD_N PF00345.20 EGB08421.1 - 8.7 6.3 5.6 30 4.5 0.1 2.5 3 0 0 3 3 3 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Sulfate_transp PF00916.20 EGB08423.1 - 9.1e-32 110.2 19.9 6.4e-17 61.4 8.1 2.1 2 0 0 2 2 2 2 Sulfate permease family Pro_isomerase PF00160.21 EGB08424.1 - 2e-33 115.9 0.1 2.5e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 EGB08425.1 - 2e-35 122.4 0.0 2.2e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Proteasome PF00227.26 EGB08426.1 - 5.8e-59 198.8 0.6 1.1e-58 197.8 0.6 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB08426.1 - 1.8e-13 49.9 0.1 3.3e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CSD PF00313.22 EGB08427.1 - 4.8e-21 74.4 0.2 5.4e-21 74.2 0.2 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EGB08427.1 - 0.00015 21.4 0.4 0.00021 20.9 0.4 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 EGB08427.1 - 0.043 13.7 0.1 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain DUF5571 PF17732.1 EGB08427.1 - 0.12 11.7 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5571) Peptidase_C97 PF05903.14 EGB08428.1 - 4.2e-08 33.1 0.0 6.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain IQ PF00612.27 EGB08428.1 - 0.063 13.1 0.7 0.12 12.2 0.7 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Tyrosinase PF00264.20 EGB08430.1 - 4.6e-16 59.8 0.1 2.4e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Common central domain of tyrosinase AMP-binding PF00501.28 EGB08431.1 - 5.9e-51 173.4 0.0 7e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB08431.1 - 6.7e-07 30.2 0.6 6.7e-07 30.2 0.6 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain LRR_4 PF12799.7 EGB08432.1 - 1.7e-17 63.2 13.9 5.4e-06 26.6 0.7 5.1 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB08432.1 - 2.3e-17 62.5 20.2 8.2e-07 28.7 1.6 5.1 2 1 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 EGB08432.1 - 7.9e-05 22.7 11.2 4.7 8.1 0.6 6.5 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 EGB08432.1 - 0.0001 21.9 6.5 0.21 11.1 0.1 3.3 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EGB08432.1 - 0.023 14.7 9.3 17 5.8 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.25 EGB08433.1 - 3.1e-35 121.8 0.0 4e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08433.1 - 1.7e-16 60.3 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB08433.1 - 0.0052 16.7 0.2 0.012 15.6 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB08433.1 - 0.0082 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGB08433.1 - 0.17 11.5 0.2 4.8 6.7 0.1 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4239 PF14023.6 EGB08436.1 - 5.6e-15 55.6 0.0 8.2e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) SNARE_assoc PF09335.11 EGB08438.1 - 5.6e-26 91.4 7.4 7.5e-26 91.0 7.4 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein Arylsulfotrans PF05935.11 EGB08439.1 - 4.9e-14 52.0 1.1 2.5e-06 26.7 0.1 2.6 2 1 1 3 3 3 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB08439.1 - 1.7e-10 40.8 0.3 2e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 EGB08439.1 - 0.0011 18.6 11.2 0.0085 15.7 0.9 4.0 3 1 0 4 4 4 2 PQQ-like domain REJ PF02010.15 EGB08441.1 - 7.3e-33 114.0 0.0 2e-32 112.6 0.0 1.5 1 1 0 1 1 1 1 REJ domain ATG7_N PF16420.5 EGB08442.1 - 9.8e-66 222.4 0.0 1.4e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EGB08442.1 - 1.6e-43 148.8 0.0 2.6e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EGB08442.1 - 0.01 15.9 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mur_ligase_C PF02875.21 EGB08442.1 - 0.12 12.7 0.9 0.43 10.9 0.1 2.3 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain Abhydrolase_3 PF07859.13 EGB08443.1 - 2.6e-22 79.7 5.5 5.1e-22 78.8 5.5 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tyrosinase PF00264.20 EGB08443.1 - 9.1e-14 52.3 0.4 1.3e-08 35.4 0.0 2.3 2 0 0 2 2 2 2 Common central domain of tyrosinase Say1_Mug180 PF10340.9 EGB08443.1 - 2.4e-09 36.5 0.0 2.3e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EGB08443.1 - 0.075 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 EGB08444.1 - 1.3e-67 228.0 0.0 1.7e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08444.1 - 6.8e-33 114.0 0.0 1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGB08444.1 - 1.6e-20 71.0 0.0 6.7e-05 22.2 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB08444.1 - 1.4e-19 70.3 1.1 9.2e-09 35.6 0.1 3.1 3 1 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB08444.1 - 4.5e-17 60.4 0.5 1.2e-05 24.8 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB08444.1 - 4.1e-12 45.7 0.0 7.6e-05 22.5 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB08444.1 - 4.5e-11 41.7 0.3 5.8e-05 22.4 0.0 4.1 4 0 0 4 4 4 2 EF hand APH PF01636.23 EGB08444.1 - 5.8e-07 29.7 3.6 8.5e-05 22.6 0.0 3.1 2 2 1 3 3 3 2 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 EGB08444.1 - 9.3e-05 22.7 0.2 0.47 10.8 0.1 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_fungal PF17667.1 EGB08444.1 - 0.0062 15.4 0.0 0.014 14.2 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase DUF1679 PF07914.11 EGB08444.1 - 0.0081 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Kinase-like PF14531.6 EGB08444.1 - 0.034 13.5 0.0 0.082 12.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EGB08444.1 - 0.037 13.6 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase EF-hand_9 PF14658.6 EGB08444.1 - 0.038 14.3 0.1 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Gcd10p PF04189.13 EGB08445.1 - 1.6e-48 165.4 0.0 2.2e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family SAC3_GANP PF03399.16 EGB08445.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 SAC3/GANP family Pkinase PF00069.25 EGB08446.1 - 2.2e-60 204.3 0.0 2.7e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08446.1 - 1.4e-29 103.2 0.0 3.7e-29 101.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB08446.1 - 2.8e-05 23.2 0.0 3.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGB08446.1 - 0.00019 21.4 0.6 0.0061 16.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB08446.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB08446.1 - 0.0013 18.1 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGB08446.1 - 0.011 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family A_deaminase PF00962.22 EGB08447.1 - 4.9e-62 210.2 0.0 7.1e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MHCassoc_trimer PF08831.10 EGB08447.1 - 0.15 12.1 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain LRR_6 PF13516.6 EGB08448.1 - 3.7e-07 29.7 1.9 2.1 8.6 0.0 6.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 EGB08448.1 - 6.5e-05 23.2 0.6 0.036 14.5 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB08448.1 - 0.00087 19.5 0.0 36 5.5 0.0 4.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 EGB08448.1 - 0.057 13.2 0.2 43 4.0 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat Mago-bind PF09282.10 EGB08448.1 - 0.16 11.9 0.9 0.57 10.1 0.9 2.0 1 0 0 1 1 1 0 Mago binding Radical_SAM PF04055.21 EGB08449.1 - 8.5e-09 36.0 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Lipase_GDSL_2 PF13472.6 EGB08449.1 - 0.074 13.4 0.1 0.22 11.9 0.1 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Myb_DNA-binding PF00249.31 EGB08450.1 - 6.2e-34 115.9 5.7 3.2e-12 46.4 0.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB08450.1 - 5.1e-33 113.1 0.9 2.8e-11 43.5 0.1 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EGB08450.1 - 1.6e-05 24.9 0.1 0.16 12.1 0.1 3.1 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EGB08450.1 - 0.016 15.1 0.1 0.43 10.5 0.0 2.6 2 1 1 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EGB08450.1 - 0.017 15.5 5.4 0.13 12.7 0.1 3.3 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Phage_TAC_11 PF11836.8 EGB08450.1 - 0.055 13.6 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 Phage tail tube protein, GTA-gp10 Syntaxin_2 PF14523.6 EGB08451.1 - 9.5e-15 54.8 0.3 6.7e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 Syntaxin-like protein Syntaxin PF00804.25 EGB08451.1 - 3e-05 23.8 7.7 0.00026 20.7 3.3 2.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EGB08451.1 - 0.00023 21.1 0.2 0.011 15.7 0.0 2.9 2 0 0 2 2 2 1 SNARE domain Talin_middle PF09141.10 EGB08451.1 - 0.00099 19.2 0.8 0.0093 16.0 0.1 2.2 2 0 0 2 2 2 1 Talin, middle domain Elf4 PF07011.11 EGB08451.1 - 0.0088 15.9 0.4 0.048 13.6 0.1 2.4 3 1 1 4 4 4 1 Early Flowering 4 domain EDR1 PF14381.6 EGB08451.1 - 0.026 14.3 0.6 4 7.1 0.1 2.1 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 FliS PF02561.14 EGB08451.1 - 0.036 14.3 2.1 0.36 11.1 0.7 2.4 2 0 0 2 2 2 0 Flagellar protein FliS AlaDh_PNT_C PF01262.21 EGB08451.1 - 0.1 11.9 1.1 0.13 11.5 0.4 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CK2S PF15011.6 EGB08451.1 - 0.24 11.3 3.6 0.56 10.1 1.0 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate Terminase_2 PF03592.16 EGB08451.1 - 0.28 11.7 2.0 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 Terminase small subunit ISG65-75 PF11727.8 EGB08451.1 - 0.39 9.9 7.7 0.96 8.6 2.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.12 EGB08451.1 - 0.48 10.5 5.0 13 5.9 2.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlgN PF05130.12 EGB08451.1 - 0.53 10.8 6.7 6.3 7.3 3.1 2.3 2 0 0 2 2 2 0 FlgN protein NPV_P10 PF05531.12 EGB08451.1 - 0.77 10.3 4.1 33 5.0 1.6 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EGB08451.1 - 0.85 9.9 3.4 4.9 7.5 0.6 3.1 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 EGB08451.1 - 1.3 9.5 6.0 4.5 7.8 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 EGB08451.1 - 1.8 9.2 12.3 1.7 9.3 0.6 3.7 2 2 1 3 3 3 0 SlyX MCPsignal PF00015.21 EGB08451.1 - 2.4 7.9 8.7 0.11 12.2 1.1 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FUSC PF04632.12 EGB08451.1 - 5.4 5.4 11.3 0.67 8.4 5.8 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family U-box PF04564.15 EGB08452.1 - 2.4e-19 69.3 0.0 5.1e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain CSD PF00313.22 EGB08452.1 - 4e-10 39.4 0.1 7.4e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain SAM_1 PF00536.30 EGB08452.1 - 0.00034 21.0 0.0 0.00061 20.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-Nse PF11789.8 EGB08452.1 - 0.00036 20.3 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit OB_RNB PF08206.11 EGB08452.1 - 0.00053 19.6 0.4 0.0013 18.3 0.4 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain zf-NOSIP PF15906.5 EGB08452.1 - 0.0084 16.2 0.1 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGB08452.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF4366 PF14283.6 EGB08452.1 - 0.09 12.8 1.3 0.28 11.2 1.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) G8 PF10162.9 EGB08453.1 - 2.6e-18 66.3 0.1 5.3e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 EGB08453.1 - 0.039 13.8 0.2 0.17 11.8 0.2 2.0 2 0 0 2 2 2 0 Right handed beta helix region Cpn60_TCP1 PF00118.24 EGB08454.1 - 1.4e-152 508.8 13.7 1.5e-152 508.6 13.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myotub-related PF06602.14 EGB08455.1 - 6.3e-101 337.8 0.0 7.5e-101 337.6 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGB08455.1 - 0.0075 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGB08455.1 - 0.0099 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGB08455.1 - 0.031 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Methyltransf_25 PF13649.6 EGB08456.1 - 1.9e-10 41.3 0.0 5.5e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB08456.1 - 1.4e-09 38.5 0.2 2.3e-08 34.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB08456.1 - 3.6e-06 27.7 0.0 1.1e-05 26.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB08456.1 - 0.00019 21.3 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB08456.1 - 0.00068 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGB08456.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MadL PF03817.13 EGB08456.1 - 0.22 11.5 0.9 0.48 10.5 0.9 1.5 1 0 0 1 1 1 0 Malonate transporter MadL subunit PAE PF03283.13 EGB08458.1 - 8.7e-53 179.7 0.0 1.7e-52 178.7 0.0 1.4 1 1 0 1 1 1 1 Pectinacetylesterase TLD PF07534.16 EGB08459.1 - 5.4e-28 97.9 0.0 3.2e-27 95.4 0.0 1.9 1 1 0 1 1 1 1 TLD DEC-1_N PF04625.13 EGB08459.1 - 5.8 5.8 6.0 7.2 5.5 6.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region OGG_N PF07934.12 EGB08460.1 - 5.6e-20 71.6 0.0 8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EGB08460.1 - 2.3e-15 57.0 0.0 3.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGB08460.1 - 0.016 15.0 0.1 0.086 12.8 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif FMO-like PF00743.19 EGB08461.1 - 1.4e-22 79.9 0.2 1.5e-18 66.6 0.0 3.3 3 1 1 4 4 4 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGB08461.1 - 2.9e-12 46.5 0.0 3.9e-08 32.9 0.0 3.8 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB08461.1 - 4.9e-07 29.2 0.8 0.0012 18.0 0.0 3.4 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Beta-lactamase PF00144.24 EGB08462.1 - 2.1e-26 92.9 5.7 2e-25 89.8 5.7 2.2 1 1 0 1 1 1 1 Beta-lactamase DMT_YdcZ PF04657.13 EGB08462.1 - 3.4e-18 66.3 10.9 1.2e-13 51.6 2.7 3.5 2 1 1 3 3 3 3 Putative inner membrane exporter, YdcZ FGGY_N PF00370.21 EGB08464.1 - 6e-57 193.0 0.0 7.8e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGB08464.1 - 2.4e-47 161.2 5.4 5.6e-47 160.0 5.4 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain G_glu_transpept PF01019.21 EGB08465.1 - 1.1e-124 417.1 0.0 1.2e-124 416.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PQQ_2 PF13360.6 EGB08465.1 - 0.093 12.3 0.1 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain LSM PF01423.22 EGB08466.1 - 1.7e-16 59.7 0.0 2.3e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGB08466.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain WW PF00397.26 EGB08467.1 - 5.9e-16 58.3 14.2 4.5e-07 29.9 1.3 7.1 7 0 0 7 7 7 4 WW domain Ank_4 PF13637.6 EGB08467.1 - 2.7e-11 43.7 0.0 0.00019 21.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB08467.1 - 5.4e-11 42.9 0.0 0.00018 22.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB08467.1 - 5.7e-05 23.3 0.5 0.027 14.8 0.0 2.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) ASCH PF04266.14 EGB08467.1 - 0.00011 22.8 0.0 0.00025 21.6 0.0 1.5 1 0 0 1 1 1 1 ASCH domain Ank_3 PF13606.6 EGB08467.1 - 0.00011 22.3 0.1 3.9 8.4 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EGB08467.1 - 0.0095 16.4 0.3 2.5 8.7 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat MFS_1 PF07690.16 EGB08468.1 - 8.2e-06 25.0 14.1 5.8e-05 22.2 14.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Rhodanese PF00581.20 EGB08469.1 - 4.1e-17 62.6 0.0 4e-09 36.9 0.0 2.3 2 1 0 2 2 2 2 Rhodanese-like domain AMP-binding PF00501.28 EGB08470.1 - 6.5e-79 265.5 0.0 2.8e-78 263.4 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Herpes_IE2_3 PF03361.14 EGB08470.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Homoserine_dh PF00742.19 EGB08471.1 - 5.7e-43 146.8 0.0 8.4e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGB08471.1 - 1.5e-08 35.3 1.1 3.3e-08 34.2 1.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain YSIRK_signal PF04650.17 EGB08471.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 YSIRK type signal peptide Epimerase PF01370.21 EGB08472.1 - 4.9e-22 78.6 2.0 2.9e-21 76.0 0.3 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DnaJ PF00226.31 EGB08472.1 - 2.5e-17 62.7 0.1 5e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain 3Beta_HSD PF01073.19 EGB08472.1 - 1.2e-14 54.0 0.0 1.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGB08472.1 - 7.2e-13 48.8 2.5 7.2e-13 48.8 2.5 3.1 3 0 0 3 3 3 1 NAD(P)H-binding NmrA PF05368.13 EGB08472.1 - 2.4e-10 40.4 3.0 6.7e-10 38.9 1.7 2.2 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 EGB08472.1 - 1e-09 37.9 0.0 2.8e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EGB08472.1 - 5e-08 32.7 0.1 1.1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase HAD_2 PF13419.6 EGB08472.1 - 0.0088 16.1 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EGB08472.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Pho88 PF10032.9 EGB08473.1 - 2.5e-47 160.5 0.0 2.9e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) AAA_5 PF07728.14 EGB08474.1 - 1.3e-82 274.6 0.0 2.7e-28 98.7 0.0 3.4 4 0 0 4 4 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB08474.1 - 1.5e-08 35.0 0.2 0.058 13.7 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGB08474.1 - 1.5e-07 31.9 6.7 0.037 14.4 0.0 5.1 4 1 0 5 5 5 2 AAA ATPase domain AAA_3 PF07726.11 EGB08474.1 - 0.0005 19.9 0.0 0.96 9.3 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGB08474.1 - 0.00099 18.7 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 EGB08474.1 - 0.0011 19.4 0.0 0.45 11.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGB08474.1 - 0.002 17.9 0.0 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGB08474.1 - 0.0035 17.4 0.0 0.83 9.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGB08474.1 - 0.0051 16.2 0.1 0.08 12.3 0.0 2.9 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 EGB08474.1 - 0.0086 16.3 0.0 3 8.1 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EGB08474.1 - 0.0096 15.9 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGB08474.1 - 0.018 15.2 0.0 2.2 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB08474.1 - 0.019 14.9 0.0 8.1 6.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 EGB08474.1 - 0.02 14.6 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.27 EGB08474.1 - 0.035 14.6 0.0 0.64 10.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 EGB08474.1 - 0.041 13.6 0.0 4.5 7.0 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_2 PF07724.14 EGB08474.1 - 0.078 13.1 0.0 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 EGB08474.1 - 0.14 12.1 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 EGB08474.1 - 0.17 12.3 0.0 6.1 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase UPF0061 PF02696.14 EGB08475.1 - 4e-41 141.3 0.0 6.9e-40 137.2 0.0 2.6 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family EF-hand_6 PF13405.6 EGB08476.1 - 4.1e-15 54.4 6.6 0.00073 19.3 0.1 5.6 5 1 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 EGB08476.1 - 8.7e-14 50.0 5.7 0.00061 19.2 0.1 5.6 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 EGB08476.1 - 6.6e-12 45.7 4.1 0.0019 18.6 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB08476.1 - 4.4e-10 38.6 5.7 0.026 14.0 0.1 5.1 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EGB08476.1 - 0.00012 21.9 5.6 1 9.2 0.5 5.8 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_11 PF08976.11 EGB08476.1 - 0.0019 19.1 0.0 0.75 10.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 EGB08476.1 - 0.068 13.0 0.1 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 EGB08476.1 - 0.14 12.1 0.1 0.59 10.1 0.1 2.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand GFO_IDH_MocA PF01408.22 EGB08477.1 - 7.6e-15 55.8 0.0 1.4e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF202 PF02656.15 EGB08478.1 - 9.1e-16 58.1 4.5 1.1e-15 57.8 2.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CbtB PF09489.10 EGB08478.1 - 6 7.1 6.0 1.2 9.3 0.5 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) AMP-binding PF00501.28 EGB08479.1 - 5e-46 157.2 0.0 9.3e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB08479.1 - 4.2e-09 37.3 2.5 6.2e-09 36.7 0.5 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EGB08479.1 - 0.0015 17.5 0.0 0.36 9.6 0.1 2.1 2 0 0 2 2 2 2 GH3 auxin-responsive promoter Lipase_GDSL_2 PF13472.6 EGB08480.1 - 2.2e-06 28.2 0.5 5.6e-06 26.9 0.5 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PC-Esterase PF13839.6 EGB08481.1 - 0.0033 17.2 0.0 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PAE PF03283.13 EGB08482.1 - 1.2e-41 143.0 0.0 6e-39 134.2 0.0 2.1 1 1 1 2 2 2 2 Pectinacetylesterase Lipase_GDSL_2 PF13472.6 EGB08484.1 - 1e-08 35.8 8.6 2.2e-06 28.2 1.9 3.6 2 1 2 4 4 4 2 GDSL-like Lipase/Acylhydrolase family EGF_2 PF07974.13 EGB08487.1 - 2e-12 47.3 61.1 2.7e-05 24.4 8.6 5.8 5 1 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 EGB08487.1 - 0.0068 16.5 6.1 0.0068 16.5 6.1 4.7 4 1 0 4 4 4 2 Laminin EGF domain EGF PF00008.27 EGB08487.1 - 1.9 8.8 50.8 2.8 8.3 6.7 6.0 6 0 0 6 6 6 0 EGF-like domain GlcNAc PF11397.8 EGB08488.1 - 5.1e-49 167.6 0.2 9.2e-36 124.0 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) LPP PF04728.13 EGB08488.1 - 6.9 7.1 6.6 20 5.7 6.6 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Guanylate_cyc PF00211.20 EGB08489.1 - 3.7e-15 56.0 0.0 8.7e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain cNMP_binding PF00027.29 EGB08489.1 - 8e-15 54.7 0.0 1.9e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain AAA_16 PF13191.6 EGB08489.1 - 8.8e-12 45.7 4.3 1e-10 42.3 4.3 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGB08489.1 - 3.5e-05 24.1 0.0 0.22 11.8 0.0 3.3 2 0 0 2 2 2 2 AAA domain TPR_12 PF13424.6 EGB08489.1 - 0.00087 19.5 0.4 0.00087 19.5 0.4 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat NACHT PF05729.12 EGB08489.1 - 0.025 14.5 0.1 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF2428 PF10350.9 EGB08489.1 - 0.046 13.0 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) TPR_8 PF13181.6 EGB08489.1 - 0.26 11.6 3.4 0.74 10.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB08489.1 - 0.4 10.6 0.0 0.4 10.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 EGB08490.1 - 3e-36 125.2 0.0 5.5e-30 104.6 0.0 2.7 2 1 0 2 2 2 2 mRNA capping enzyme Rubis-subs-bind PF09273.11 EGB08490.1 - 5.2e-08 33.7 0.7 1.5e-07 32.2 0.7 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Methyltransf_25 PF13649.6 EGB08490.1 - 6.9e-07 29.9 0.1 2e-05 25.2 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB08490.1 - 4.9e-06 27.2 0.0 2.1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB08490.1 - 4.1e-05 23.4 0.0 9.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB08490.1 - 0.0015 19.1 0.1 0.035 14.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB08490.1 - 0.0021 17.9 0.0 0.0058 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGB08490.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase ELO PF01151.18 EGB08492.1 - 9.3e-61 205.5 6.4 1e-60 205.4 6.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_C1 PF00112.23 EGB08493.1 - 1.5e-38 133.0 6.5 2e-38 132.7 6.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB08493.1 - 0.095 11.5 0.4 0.15 10.8 0.4 1.2 1 0 0 1 1 1 0 Peptidase C1-like family ABC1 PF03109.16 EGB08494.1 - 5.5e-16 58.8 0.0 1.4e-15 57.4 0.0 1.7 1 1 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGB08494.1 - 4.5e-08 32.8 0.1 6.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08494.1 - 1.5e-05 24.5 0.0 0.00038 19.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGB08494.1 - 2.4e-05 24.0 0.0 5.7e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EGB08494.1 - 0.00013 22.0 1.2 0.0019 18.2 1.1 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EGB08494.1 - 0.24 10.3 0.1 0.35 9.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Methyltransf_16 PF10294.9 EGB08495.1 - 1.9e-21 76.6 0.0 2.7e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase EF-hand_7 PF13499.6 EGB08496.1 - 3.2e-06 27.5 0.0 4.2e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB08496.1 - 0.00022 20.9 0.0 0.071 13.1 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain Glyco_trans_1_2 PF13524.6 EGB08496.1 - 0.00097 19.5 0.1 0.0034 17.7 0.1 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 EF-hand_1 PF00036.32 EGB08496.1 - 0.0076 15.7 0.0 0.25 11.0 0.0 2.9 3 0 0 3 3 3 1 EF hand PhyH PF05721.13 EGB08497.1 - 1.9e-16 61.0 0.1 1.2e-08 35.5 0.0 2.9 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) Cupin_8 PF13621.6 EGB08497.1 - 1.1e-13 51.5 0.0 5.5e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB08497.1 - 2.4e-09 37.1 0.0 5e-09 36.1 0.0 1.4 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB08497.1 - 1.3e-08 34.4 0.1 0.00036 20.2 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_6 PF12852.7 EGB08497.1 - 0.00013 21.8 3.1 0.0079 15.9 0.2 2.8 2 1 0 2 2 2 2 Cupin AraC_binding PF02311.19 EGB08497.1 - 0.0045 16.9 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain 2OG-FeII_Oxy_3 PF13640.6 EGB08497.1 - 0.019 15.9 0.0 0.073 14.0 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Lyx_isomer PF07385.12 EGB08497.1 - 0.025 13.8 0.0 0.058 12.6 0.0 1.5 2 0 0 2 2 2 0 D-lyxose isomerase JmjC PF02373.22 EGB08497.1 - 0.098 13.1 0.0 2.1 8.8 0.0 2.9 3 1 0 3 3 3 0 JmjC domain, hydroxylase Clat_adaptor_s PF01217.20 EGB08498.1 - 4.3e-13 49.4 0.0 5.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ABC_tran PF00005.27 EGB08499.1 - 4.9e-19 69.2 0.0 8.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGB08499.1 - 3.4e-14 52.8 3.0 5.3e-14 52.2 3.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 EGB08499.1 - 4e-06 26.9 0.1 0.017 14.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB08499.1 - 0.0011 18.7 0.1 0.0025 17.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB08499.1 - 0.0059 17.0 0.2 0.012 16.0 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EGB08499.1 - 0.0091 15.1 2.8 0.013 14.6 2.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGB08499.1 - 0.018 14.9 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase DUF3330 PF11809.8 EGB08499.1 - 0.09 12.8 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) AAA_30 PF13604.6 EGB08499.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGB08499.1 - 0.27 11.3 0.0 0.51 10.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Helicase_C PF00271.31 EGB08500.1 - 1.1e-10 41.8 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB08500.1 - 1.8e-08 34.4 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGB08500.1 - 4.3e-06 26.6 1.4 4.3e-06 26.6 1.4 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGB08500.1 - 0.00094 19.5 0.0 0.0025 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGB08500.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EGB08500.1 - 0.082 13.3 2.2 0.22 11.9 0.8 2.5 2 1 0 2 2 2 0 AAA ATPase domain Radical_SAM PF04055.21 EGB08501.1 - 3.3e-19 69.9 0.0 4.8e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 EGB08501.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 HemN C-terminal domain cNMP_binding PF00027.29 EGB08502.1 - 5.2e-38 129.0 0.1 5.4e-18 64.9 0.1 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGB08503.1 - 7.4e-60 202.5 0.0 8.3e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08503.1 - 6.2e-32 110.9 0.0 7.5e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Herpes_Helicase PF02689.14 EGB08503.1 - 0.015 13.3 0.0 0.022 12.7 0.0 1.2 1 0 0 1 1 1 0 Helicase APH PF01636.23 EGB08503.1 - 0.21 11.5 0.0 6.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EGB08504.1 - 5.3e-54 183.2 0.0 6.2e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB08504.1 - 3.1e-48 164.4 0.0 3.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGB08504.1 - 0.03 14.2 0.0 0.06 13.3 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB08504.1 - 0.045 12.7 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain IL12 PF03039.14 EGB08504.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin-12 alpha subunit RNase_T PF00929.24 EGB08505.1 - 3.7e-11 43.8 0.0 4.7e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EGB08505.1 - 0.14 11.9 0.0 0.81 9.4 0.0 2.2 1 1 1 2 2 2 0 3'-5' exonuclease Toxin_TOLIP PF00087.21 EGB08506.1 - 0.15 12.3 10.0 0.63 10.3 9.0 2.4 1 1 1 2 2 2 0 Snake toxin and toxin-like protein Hydrolase_4 PF12146.8 EGB08507.1 - 3e-12 46.3 0.1 2.7e-10 39.9 0.0 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGB08507.1 - 2.5e-05 23.9 0.0 0.0001 21.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGB08507.1 - 5.5e-05 23.9 1.6 0.0001 23.0 1.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EGB08507.1 - 0.00021 20.9 0.0 0.071 12.7 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGB08507.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGB08507.1 - 0.0039 16.8 0.0 0.77 9.3 0.2 2.1 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 EGB08507.1 - 0.0089 16.0 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 EGB08507.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family Esterase PF00756.20 EGB08507.1 - 0.018 14.7 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase LIP PF03583.14 EGB08507.1 - 0.054 12.8 0.3 1.9 7.7 0.0 2.1 1 1 1 2 2 2 0 Secretory lipase LIDHydrolase PF10230.9 EGB08507.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 EGB08507.1 - 0.16 11.7 0.0 8.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RelA_SpoT PF04607.17 EGB08508.1 - 2.5e-21 76.1 0.0 6.7e-21 74.7 0.0 1.7 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 EGB08508.1 - 8.5e-09 35.3 1.2 6.6e-07 29.2 1.2 3.1 1 1 0 1 1 1 1 HD domain Pirin PF02678.16 EGB08509.1 - 3.2e-21 75.4 0.1 5.1e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGB08509.1 - 8.6e-21 74.3 0.0 1.2e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 EGB08509.1 - 0.031 14.4 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain PI3_PI4_kinase PF00454.27 EGB08510.1 - 2e-17 63.9 0.0 2.5e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 EGB08510.1 - 3.3e-08 33.1 0.0 6.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB08510.1 - 0.002 17.9 0.0 0.006 16.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like AglB_L1 PF18079.1 EGB08510.1 - 0.025 14.8 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain PP2C PF00481.21 EGB08511.1 - 9.5e-43 146.7 0.0 1.1e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB08511.1 - 1.7e-05 24.6 0.0 6e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB08511.1 - 7e-05 22.8 0.1 0.01 15.8 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) EF-hand_7 PF13499.6 EGB08512.1 - 8.8e-06 26.1 0.1 1.7e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB08512.1 - 0.00029 20.2 0.2 0.12 12.0 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB08512.1 - 0.001 18.8 0.2 0.059 13.3 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain FYVE PF01363.21 EGB08512.1 - 0.0034 17.5 12.2 0.0069 16.5 12.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger fn3 PF00041.21 EGB08512.1 - 0.004 17.5 0.0 0.007 16.7 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain EF-hand_5 PF13202.6 EGB08512.1 - 0.02 14.4 1.8 0.036 13.6 0.4 2.1 2 0 0 2 2 2 0 EF hand FYVE_2 PF02318.16 EGB08512.1 - 0.036 14.3 5.8 0.063 13.5 5.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 EGB08512.1 - 0.076 13.3 7.4 0.18 12.1 7.4 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TAT_signal PF10518.9 EGB08512.1 - 2 8.4 9.1 10 6.1 9.1 2.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Siva PF05458.12 EGB08512.1 - 3.2 7.4 10.5 5.7 6.6 10.5 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Methyltransf_31 PF13847.6 EGB08513.1 - 6.6e-08 32.5 0.0 8.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB08513.1 - 4.2e-07 30.6 0.3 6e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB08513.1 - 1.2e-05 25.9 0.3 1.7e-05 25.4 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGB08513.1 - 0.0039 17.0 0.0 0.006 16.3 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGB08513.1 - 0.016 15.9 0.0 0.022 15.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EGB08513.1 - 0.017 14.6 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 EGB08513.1 - 0.061 12.7 2.2 0.077 12.4 2.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB08513.1 - 0.071 12.7 0.2 0.095 12.2 0.2 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MTHFR PF02219.17 EGB08514.1 - 0.0039 16.6 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Acetyltransf_1 PF00583.25 EGB08515.1 - 4.5e-11 43.0 0.4 1.1e-10 41.8 0.3 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGB08515.1 - 5.3e-08 32.9 0.1 1.4e-07 31.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB08515.1 - 6.5e-06 26.5 0.2 1.3e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB08515.1 - 0.00043 20.2 0.1 0.003 17.5 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Bromodomain PF00439.25 EGB08516.1 - 1.6e-19 69.7 0.0 1.9e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Bromodomain NuiA PF07924.11 EGB08516.1 - 0.18 12.2 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein DUF2263 PF10021.9 EGB08517.1 - 3.2e-25 89.2 0.0 5e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Ppnp PF06865.11 EGB08517.1 - 1e-10 41.9 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase Lipase_GDSL PF00657.22 EGB08517.1 - 0.026 14.5 0.1 0.05 13.6 0.0 1.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase tRNA_int_endo PF01974.17 EGB08518.1 - 6.8e-22 77.3 0.1 1.1e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Cupin_8 PF13621.6 EGB08519.1 - 1.8e-06 27.9 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB08519.1 - 1.7e-05 24.5 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein WD40 PF00400.32 EGB08520.1 - 2.2e-19 69.4 7.6 7.8e-06 26.5 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08520.1 - 4.2e-10 39.8 0.0 0.013 15.8 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 EGB08520.1 - 4.9e-10 38.9 0.7 9.8e-10 37.9 0.1 1.9 2 0 0 2 2 2 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 EGB08520.1 - 1.8e-07 30.4 0.0 0.11 11.4 0.0 3.2 2 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 EGB08520.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EGB08520.1 - 0.01 14.5 0.0 2.5 6.6 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGB08520.1 - 0.25 11.9 4.6 17 6.1 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain LRR_9 PF14580.6 EGB08521.1 - 6.4e-18 64.9 0.0 9.1e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGB08521.1 - 5.5e-12 45.7 0.0 6.3e-05 23.3 0.1 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB08521.1 - 3.4e-11 42.7 0.5 7e-09 35.3 0.1 3.1 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 EGB08521.1 - 0.019 15.0 1.2 1e+02 3.3 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 EGB08521.1 - 0.027 15.0 0.0 53 5.0 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat ABC_transp_aux PF09822.9 EGB08522.1 - 3.4e-07 30.0 0.0 5.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.6 EGB08522.1 - 0.00019 21.8 0.0 0.00046 20.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) DDOST_48kD PF03345.14 EGB08522.1 - 0.037 12.9 0.0 0.11 11.3 0.0 1.7 1 1 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta Pterin_4a PF01329.19 EGB08523.1 - 1.4e-24 86.0 0.0 1.5e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Glyco_hydro_47 PF01532.20 EGB08524.1 - 2.2e-15 56.5 0.0 2.4e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Na_H_Exchanger PF00999.21 EGB08525.1 - 1.8e-32 112.6 26.1 2.3e-32 112.2 26.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mpv17_PMP22 PF04117.12 EGB08526.1 - 3.8e-16 59.1 0.2 6.4e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3127 PF11325.8 EGB08528.1 - 3.8e-11 43.1 0.0 5.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3127) Amidase PF01425.21 EGB08529.1 - 1.1e-102 344.3 7.7 2.7e-102 343.0 7.7 1.5 1 1 0 1 1 1 1 Amidase AAA PF00004.29 EGB08530.1 - 2.4e-37 128.3 0.0 4.6e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB08530.1 - 2.2e-08 33.8 1.4 5e-08 32.6 0.2 2.4 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 EGB08530.1 - 7.7e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB08530.1 - 2.8e-05 24.4 0.1 0.0035 17.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGB08530.1 - 0.0002 21.3 0.1 0.00064 19.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB08530.1 - 0.00023 21.6 4.1 0.038 14.4 4.1 3.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EGB08530.1 - 0.00074 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGB08530.1 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGB08530.1 - 0.0027 17.7 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGB08530.1 - 0.0028 17.1 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGB08530.1 - 0.0054 17.0 0.1 0.014 15.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 EGB08530.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EGB08530.1 - 0.0074 15.9 0.7 0.026 14.1 0.2 2.1 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 EGB08530.1 - 0.0075 16.3 0.0 0.027 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB08530.1 - 0.011 16.3 1.9 0.011 16.2 0.0 2.1 3 0 0 3 3 1 0 AAA domain Sigma54_activat PF00158.26 EGB08530.1 - 0.015 15.0 0.0 0.71 9.6 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_2 PF07724.14 EGB08530.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGB08530.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EGB08530.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGB08530.1 - 0.064 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 EGB08530.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region LisH PF08513.11 EGB08530.1 - 0.085 12.9 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 LisH NACHT PF05729.12 EGB08530.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 EGB08530.1 - 0.17 11.2 0.3 6.2 6.1 0.1 2.1 1 1 1 2 2 2 0 KaiC Ribosomal_S8e PF01201.22 EGB08531.1 - 5.9e-49 165.8 1.6 2.8e-48 163.6 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein S8e KinB_sensor PF16767.5 EGB08531.1 - 0.064 13.7 0.3 0.11 13.0 0.3 1.3 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB TPT PF03151.16 EGB08532.1 - 2.8e-07 30.2 11.5 0.0013 18.1 2.8 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EGB08532.1 - 0.014 15.6 22.7 0.088 13.0 7.6 2.9 1 1 2 3 3 3 0 EamA-like transporter family UAA PF08449.11 EGB08532.1 - 0.065 12.4 15.1 0.18 11.0 15.1 1.7 1 1 0 1 1 1 0 UAA transporter family PP-binding PF00550.25 EGB08533.1 - 1.6e-12 47.6 0.6 2.9e-12 46.8 0.6 1.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGB08533.1 - 0.074 13.3 0.4 0.075 13.3 0.4 1.3 1 1 0 1 1 1 0 Acyl-carrier Jun PF03957.13 EGB08534.1 - 0.24 11.2 1.3 0.5 10.2 1.3 1.5 1 0 0 1 1 1 0 Jun-like transcription factor Acyl-CoA_dh_M PF02770.19 EGB08535.1 - 2e-10 40.7 0.1 4.4e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ThrE PF06738.12 EGB08536.1 - 6.8e-06 25.6 16.8 0.00011 21.7 6.0 2.7 3 0 0 3 3 3 2 Putative threonine/serine exporter Arylsulfotrans PF05935.11 EGB08536.1 - 0.00017 20.6 0.2 0.0012 17.8 0.2 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB08536.1 - 0.026 13.9 0.4 0.086 12.2 0.4 1.7 1 1 0 1 1 1 0 Arylsulfotransferase (ASST) UAA PF08449.11 EGB08537.1 - 4.7e-33 114.7 0.0 5.5e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB08537.1 - 1.4e-05 25.3 13.4 0.0019 18.4 6.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGB08537.1 - 0.0026 17.1 0.6 0.0033 16.8 0.6 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 EGB08537.1 - 0.0049 15.9 0.0 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Pkinase PF00069.25 EGB08538.1 - 8.9e-32 110.5 0.0 1e-31 110.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08538.1 - 1.6e-11 44.0 0.0 1.8e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB08538.1 - 0.00016 21.1 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB08538.1 - 0.00056 19.9 0.1 0.00093 19.2 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB08538.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB08538.1 - 0.19 10.4 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EGB08540.1 - 4.3e-61 206.6 0.0 5.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08540.1 - 2.7e-28 99.0 0.0 3.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB08540.1 - 4.5e-05 22.6 0.7 7e-05 21.9 0.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB08540.1 - 0.00098 18.5 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB08540.1 - 0.071 11.9 0.0 0.45 9.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EGB08540.1 - 0.098 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3275 PF11679.8 EGB08540.1 - 1.8 8.5 5.3 3.8 7.4 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) cNMP_binding PF00027.29 EGB08541.1 - 3.4e-25 87.9 0.0 2.2e-19 69.3 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain U-box PF04564.15 EGB08542.1 - 1.9e-18 66.4 0.0 2.2e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB08542.1 - 8.8e-06 25.4 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 EGB08542.1 - 0.049 13.0 0.0 0.049 13.0 0.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger zf-NOSIP PF15906.5 EGB08542.1 - 0.072 13.2 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Vps35 PF03635.17 EGB08543.1 - 6.8e-06 24.9 0.0 0.0028 16.2 0.0 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 DnaJ_C PF01556.18 EGB08544.1 - 5.8e-20 71.9 0.0 9.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB08544.1 - 7.3e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGB08544.1 - 2.2e-07 31.1 8.5 3.9e-07 30.3 8.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Lebercilin PF15619.6 EGB08544.1 - 1.5 8.4 17.6 5.1 6.7 17.6 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc24 PF08286.11 EGB08544.1 - 5.1 7.4 5.1 13 6.1 5.1 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Med9 PF07544.13 EGB08544.1 - 5.2 7.2 7.1 13 6.0 0.9 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.8 EGB08544.1 - 8.3 6.5 14.5 16 5.5 14.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PATR PF12951.7 EGB08545.1 - 0.089 12.9 0.5 25 5.1 0.1 2.8 2 0 0 2 2 2 0 Passenger-associated-transport-repeat DHHC PF01529.20 EGB08547.1 - 1.3e-12 47.9 0.0 2.5e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EGB08547.1 - 1.7e-10 41.3 0.2 4.8e-08 33.5 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB08547.1 - 1.8e-08 34.0 0.2 0.21 12.2 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGB08547.1 - 4.4e-08 33.5 0.1 0.52 11.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB08547.1 - 3.5e-07 30.4 5.5 0.00031 21.0 0.2 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB08547.1 - 0.00083 19.7 4.5 0.13 12.8 0.2 3.9 3 0 0 3 3 3 1 Ankyrin repeat Herpes_BLRF2 PF05812.12 EGB08547.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein EamA PF00892.20 EGB08547.1 - 4.4 7.5 8.2 8.7 6.5 1.1 2.2 2 0 0 2 2 2 0 EamA-like transporter family Chorein_N PF12624.7 EGB08549.1 - 9.2e-10 38.7 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 2OG-FeII_Oxy_5 PF13759.6 EGB08549.1 - 1.7e-06 28.4 0.0 3.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Lipase_GDSL_2 PF13472.6 EGB08550.1 - 1.5e-22 80.8 3.5 3.1e-22 79.8 3.5 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB08550.1 - 2.7e-12 47.1 0.0 3.9e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Oxidored_q2 PF00420.24 EGB08550.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Herpes_gE PF02480.16 EGB08550.1 - 0.18 10.6 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SPX PF03105.19 EGB08550.1 - 6.3 6.6 9.2 9.2 6.1 9.2 1.3 1 0 0 1 1 1 0 SPX domain Phytochelatin PF05023.14 EGB08551.1 - 3.8e-51 173.3 0.0 4.4e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase Snf7 PF03357.21 EGB08552.1 - 6.8e-20 71.4 9.9 8e-20 71.1 9.9 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 EGB08552.1 - 2.5e-07 30.8 3.7 4e-07 30.1 3.7 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.8 EGB08552.1 - 0.074 13.4 7.1 0.72 10.2 3.3 2.1 1 1 1 2 2 2 0 YlqD protein Wbp11 PF09429.10 EGB08552.1 - 0.098 13.1 5.1 0.55 10.7 0.1 2.5 2 0 0 2 2 2 0 WW domain binding protein 11 NuA4 PF09340.10 EGB08552.1 - 0.17 11.8 1.7 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF4710 PF15828.5 EGB08552.1 - 0.9 9.7 7.6 0.69 10.1 5.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) PspA_IM30 PF04012.12 EGB08552.1 - 1.3 8.6 14.2 54 3.3 14.2 2.6 1 1 0 1 1 1 0 PspA/IM30 family RasGAP_C PF03836.15 EGB08552.1 - 1.6 8.9 8.4 8.6 6.5 8.4 2.1 1 1 0 1 1 1 0 RasGAP C-terminus DUF5093 PF17011.5 EGB08552.1 - 3.8 7.8 9.6 6.8 7.0 4.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) C2 PF00168.30 EGB08553.1 - 7e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 EGB08553.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain FGGY_C PF02782.16 EGB08554.1 - 5.3e-44 150.3 1.5 8.5e-44 149.7 1.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGB08554.1 - 1.1e-13 51.4 0.0 2.7e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain B12D PF06522.11 EGB08554.1 - 1.5 8.7 4.3 38 4.2 0.0 3.5 4 0 0 4 4 4 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PDEase_I PF00233.19 EGB08555.1 - 2.9e-66 223.6 0.0 3.6e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EGB08555.1 - 0.0038 17.5 0.1 0.0075 16.5 0.1 1.5 1 0 0 1 1 1 1 HD domain RCC1 PF00415.18 EGB08556.1 - 9.3e-14 51.8 8.5 2.4e-13 50.5 0.2 2.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB08556.1 - 7e-11 41.6 8.3 2.4e-08 33.6 0.5 2.2 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 EGB08557.1 - 2.8e-49 164.0 0.0 6.8e-07 29.9 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08557.1 - 5.7e-11 42.6 0.1 1.4 9.3 0.0 5.4 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB08557.1 - 9e-08 31.2 0.0 0.81 8.3 0.0 5.3 1 1 5 6 6 6 3 Nucleoporin Nup120/160 GDPD_2 PF13653.6 EGB08557.1 - 4.8e-06 26.9 1.0 75 4.0 0.0 6.2 6 0 0 6 6 6 0 Glycerophosphoryl diester phosphodiesterase family DUF1036 PF06282.11 EGB08557.1 - 1.2e-05 25.8 0.0 15 6.2 0.0 4.8 2 1 3 5 5 5 0 Protein of unknown function (DUF1036) PALB2_WD40 PF16756.5 EGB08557.1 - 0.0017 17.3 2.0 17 4.2 0.0 4.4 1 1 3 5 5 5 0 Partner and localizer of BRCA2 WD40 domain DUF642 PF04862.12 EGB08557.1 - 0.0018 18.1 0.0 5.4 6.8 0.0 3.5 1 1 1 3 3 3 1 Protein of unknown function (DUF642) DUF3592 PF12158.8 EGB08557.1 - 0.0031 17.6 0.3 17 5.4 0.3 4.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) DUF1541 PF07563.11 EGB08557.1 - 0.0077 16.1 0.0 7.9 6.4 0.0 3.0 4 0 0 4 4 4 2 Protein of unknown function (DUF1541) EpCAM_N PF18635.1 EGB08557.1 - 0.055 13.6 0.1 48 4.2 0.0 4.3 5 0 0 5 5 5 0 Epithelial cell adhesion molecule N-terminal domain B3_4 PF03483.17 EGB08557.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.3 1 1 2 3 3 3 0 B3/4 domain Cuticle_4 PF15955.5 EGB08557.1 - 0.16 12.7 3.5 1.4e+02 3.3 0.0 5.2 6 0 0 6 6 6 0 Cuticle protein NAD_Gly3P_dh_N PF01210.23 EGB08557.1 - 0.21 11.5 0.0 70 3.4 0.0 4.0 5 1 0 6 6 6 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus BmKX PF09132.10 EGB08557.1 - 8.1 6.5 9.2 5.7e+02 0.6 0.1 5.9 6 0 0 6 6 6 0 BmKX DUF1635 PF07795.11 EGB08559.1 - 0.016 15.1 5.0 0.016 15.1 5.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) DASH_Hsk3 PF08227.11 EGB08559.1 - 0.054 13.9 4.0 0.32 11.4 1.0 3.0 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF4407 PF14362.6 EGB08559.1 - 7.7 5.8 24.6 0.55 9.5 12.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ECH_1 PF00378.20 EGB08560.1 - 5.4e-42 143.8 0.9 8e-42 143.3 0.9 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB08560.1 - 1.7e-38 132.9 0.2 2.1e-38 132.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGB08560.1 - 0.056 13.4 0.3 11 6.0 0.0 2.5 2 1 1 3 3 3 0 Peptidase family S49 SNF2_N PF00176.23 EGB08561.1 - 1.4e-28 99.7 0.0 2.9e-28 98.6 0.0 1.4 1 1 1 2 2 2 1 SNF2 family N-terminal domain Sod_Ni PF09055.11 EGB08561.1 - 6.6e-25 88.1 3.0 1.2e-24 87.3 3.0 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Helicase_C PF00271.31 EGB08561.1 - 2.4e-08 34.3 0.0 4.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB08561.1 - 1.4e-06 28.4 0.0 5.4e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Nucleo_P87 PF07267.11 EGB08561.1 - 4.6 6.0 7.2 10 4.8 7.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2064 PF09837.9 EGB08562.1 - 6.9e-17 61.4 0.2 1.1e-16 60.7 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) GSHPx PF00255.19 EGB08563.1 - 1.1e-11 44.2 0.0 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4498 PF14926.6 EGB08564.1 - 7.2e-33 113.9 0.0 8.6e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) PAP_fibrillin PF04755.12 EGB08565.1 - 0.00047 20.2 0.0 0.0082 16.1 0.0 2.2 1 1 0 1 1 1 1 PAP_fibrillin Acetyltransf_1 PF00583.25 EGB08566.1 - 9.7e-08 32.3 0.1 1.9e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EGB08566.1 - 2.2e-05 24.5 0.0 5.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB08566.1 - 3.2e-05 24.3 0.1 6.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGB08566.1 - 0.00058 19.8 0.1 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB08566.1 - 0.06 13.3 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 FR47-like protein LRR_8 PF13855.6 EGB08567.1 - 1.6e-42 143.1 41.6 1.4e-12 47.2 3.7 3.5 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EGB08567.1 - 6.5e-13 48.6 9.0 8.2e-05 22.9 0.9 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) DASH_Dam1 PF08653.10 EGB08567.1 - 0.00054 19.7 6.4 3.8 7.4 0.1 4.8 2 1 3 5 5 5 3 DASH complex subunit Dam1 LRR_5 PF13306.6 EGB08567.1 - 0.02 14.8 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Pigment_DH PF06324.11 EGB08567.1 - 0.025 14.6 3.4 2.1e+02 2.3 0.0 5.8 6 0 0 6 6 6 0 Pigment-dispersing hormone (PDH) Cys_Met_Meta_PP PF01053.20 EGB08567.1 - 0.11 11.0 0.3 10 4.5 0.0 3.1 1 1 1 3 3 3 0 Cys/Met metabolism PLP-dependent enzyme LRR_6 PF13516.6 EGB08567.1 - 6.1 7.2 6.9 22 5.4 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Glyco_tranf_2_3 PF13641.6 EGB08568.1 - 4e-16 59.6 0.2 5.3e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGB08568.1 - 7.7e-13 48.6 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 MCD_N PF17408.2 EGB08568.1 - 0.00064 19.8 0.1 0.022 14.9 0.2 2.3 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase N-terminal domain Glyco_transf_21 PF13506.6 EGB08568.1 - 0.0042 16.6 0.2 0.012 15.2 0.1 1.7 1 1 1 2 2 2 1 Glycosyl transferase family 21 GlcNAc PF11397.8 EGB08568.1 - 0.046 13.2 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Glyco_tranf_2_2 PF10111.9 EGB08568.1 - 0.16 11.4 0.0 5.1 6.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Aldedh PF00171.22 EGB08569.1 - 4e-131 437.7 0.0 4.7e-131 437.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LRR_4 PF12799.7 EGB08570.1 - 1.7e-25 88.6 0.4 0.00038 20.8 0.0 5.7 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB08570.1 - 3.8e-18 65.0 11.1 0.0016 18.1 0.0 5.9 3 2 2 6 6 6 6 Leucine rich repeat Sacchrp_dh_NADP PF03435.18 EGB08570.1 - 3.4e-07 30.6 0.0 8.7e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain LRR_9 PF14580.6 EGB08570.1 - 4.1e-06 26.4 0.3 0.018 14.5 0.0 3.3 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 EGB08570.1 - 0.00063 19.9 4.2 51 5.0 0.2 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 EGB08570.1 - 0.0015 18.4 17.7 19 5.6 0.0 8.6 9 0 0 9 9 9 1 Leucine Rich repeat DUF3330 PF11809.8 EGB08570.1 - 0.021 14.9 0.0 11 6.2 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3330) SecE PF00584.20 EGB08571.1 - 4.9e-13 48.8 0.2 9.1e-13 47.9 0.2 1.4 1 1 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Tyrosinase PF00264.20 EGB08572.1 - 9.4e-10 39.2 8.3 1.9e-06 28.3 4.9 2.3 2 0 0 2 2 2 2 Common central domain of tyrosinase Sugar_tr PF00083.24 EGB08574.1 - 9.6e-54 182.9 2.9 6.3e-33 114.3 0.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGB08574.1 - 8.7e-19 67.6 26.3 5.9e-15 55.0 9.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGB08574.1 - 0.0074 14.8 0.6 0.0074 14.8 0.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7TMR-DISM_7TM PF07695.11 EGB08574.1 - 3.7 7.4 10.8 0.14 12.0 1.7 2.3 2 1 0 2 2 2 0 7TM diverse intracellular signalling MR_MLE_C PF13378.6 EGB08575.1 - 1.3e-53 181.8 1.0 1.3e-53 181.8 1.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGB08575.1 - 1.6e-17 63.8 0.0 4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain FA_hydroxylase PF04116.13 EGB08576.1 - 1.8e-26 93.0 15.1 2.1e-26 92.9 15.1 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Ax_dynein_light PF10211.9 EGB08577.1 - 6.6e-56 189.2 0.0 7.8e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain DUF3648 PF12364.8 EGB08577.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) MCRA PF06100.11 EGB08577.1 - 0.17 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pro-kuma_activ PF09286.11 EGB08578.1 - 1.4e-12 48.1 0.0 2.8e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGB08578.1 - 2.3e-07 30.4 0.1 8e-07 28.6 0.1 1.7 1 1 0 1 1 1 1 Subtilase family Patched PF02460.18 EGB08580.1 - 1.5e-52 178.8 14.6 2.9e-30 105.1 7.2 3.5 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EGB08580.1 - 2.6e-22 79.3 13.6 2.5e-16 59.9 0.1 3.3 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation PsbN PF02468.15 EGB08580.1 - 0.089 12.7 1.1 19 5.2 0.2 3.3 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF4185 PF13810.6 EGB08581.1 - 2.5e-19 69.6 2.0 5.5e-19 68.6 2.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) DUF5005 PF16396.5 EGB08581.1 - 0.01 14.5 0.1 0.044 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5005) Transgly_assoc PF04226.13 EGB08582.1 - 4.5 7.6 7.4 5.9 7.2 5.7 1.9 1 1 1 2 2 2 0 Transglycosylase associated protein NMT1 PF09084.11 EGB08583.1 - 1.1e-07 32.0 0.0 1.2e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EGB08583.1 - 9.7e-06 25.2 0.0 1.2e-05 24.9 0.0 1.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 EGB08583.1 - 0.066 12.9 0.2 9.6 5.8 0.1 2.2 1 1 1 2 2 2 0 NMT1-like family EF-hand_1 PF00036.32 EGB08584.1 - 4e-10 38.5 2.6 0.0022 17.4 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB08584.1 - 6.4e-09 35.0 1.7 0.011 15.6 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EGB08584.1 - 1.7e-06 28.4 3.9 7.5e-06 26.3 1.6 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB08584.1 - 1e-05 24.8 1.9 0.032 13.7 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGB08584.1 - 0.089 12.6 3.1 0.1 12.5 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain pair DUF507 PF04368.13 EGB08584.1 - 0.11 12.4 0.8 0.2 11.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF507) EF-hand_4 PF12763.7 EGB08584.1 - 0.27 11.2 3.7 6.9 6.7 0.1 2.9 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand cNMP_binding PF00027.29 EGB08585.1 - 2.4e-14 53.1 0.1 4.9e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain YesK PF14150.6 EGB08586.1 - 0.056 13.6 0.4 0.056 13.6 0.4 1.8 2 0 0 2 2 2 0 YesK-like protein DUF2587 PF10759.9 EGB08586.1 - 0.083 12.4 0.5 0.17 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Peptidase_M24 PF00557.24 EGB08587.1 - 3.4e-51 173.9 0.3 4.1e-51 173.7 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PPDK_N PF01326.19 EGB08589.1 - 1.3e-53 182.4 0.0 1.8e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 EGB08589.1 - 1.6e-17 63.0 0.4 5.1e-17 61.3 0.4 2.0 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PC-Esterase PF13839.6 EGB08589.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p EF-hand_1 PF00036.32 EGB08590.1 - 7.5e-24 81.5 1.9 1.2e-06 27.6 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB08590.1 - 9.2e-21 72.0 3.5 1e-06 28.1 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB08590.1 - 5e-20 70.0 4.6 4.8e-07 29.0 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGB08590.1 - 2.5e-19 69.5 3.8 4.1e-10 40.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB08590.1 - 5.7e-13 48.5 2.9 4.8e-06 26.3 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB08590.1 - 0.0016 18.7 0.0 0.93 9.8 0.0 2.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGB08590.1 - 0.029 14.2 0.0 11 5.9 0.0 2.5 3 0 0 3 3 3 0 EF hand EF-hand_11 PF08976.11 EGB08590.1 - 0.15 13.0 0.0 24 5.9 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Excalibur PF05901.11 EGB08590.1 - 1.2 9.8 7.6 11 6.8 0.3 3.6 3 1 1 4 4 4 0 Excalibur calcium-binding domain SQS_PSY PF00494.19 EGB08591.1 - 1.7e-50 172.0 4.5 1.9e-50 171.8 4.5 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase DapB_C PF05173.14 EGB08592.1 - 4.9e-18 65.3 0.1 7.3e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 EGB08592.1 - 2.1e-12 47.3 2.1 2.3e-12 47.1 0.8 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Glyco_hydro81C PF17652.1 EGB08593.1 - 2.2e-63 214.6 0.0 5.6e-63 213.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EGB08593.1 - 1.3e-16 60.7 0.0 4.8e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain Thionin PF00321.17 EGB08593.1 - 2.9 8.5 10.7 2.8 8.5 2.1 2.4 2 0 0 2 2 2 0 Plant thionin TPT PF03151.16 EGB08594.1 - 2.3e-90 302.9 7.7 2.5e-90 302.7 7.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB08594.1 - 5.3e-06 26.6 26.9 0.0001 22.5 10.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGB08594.1 - 2.7e-05 23.6 1.8 2.7e-05 23.6 1.8 1.6 1 1 1 2 2 2 1 UAA transporter family Glyco_transf_18 PF15024.6 EGB08594.1 - 0.26 9.8 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 Aldo_ket_red PF00248.21 EGB08595.1 - 6.2e-18 65.0 0.0 1.2e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Helicase_C PF00271.31 EGB08596.1 - 9.2e-09 35.6 0.0 1.2e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Maf_N PF08383.11 EGB08596.1 - 0.16 11.8 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Maf N-terminal region DUF4440 PF14534.6 EGB08597.1 - 0.022 15.1 0.1 0.04 14.3 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) zf-ANAPC11 PF12861.7 EGB08598.1 - 8.6e-28 96.3 5.9 9.4e-28 96.1 5.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGB08598.1 - 4.9e-21 74.8 3.8 6.7e-21 74.3 3.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGB08598.1 - 2.3e-11 43.8 6.9 8.2e-11 42.1 6.9 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB08598.1 - 6.1e-09 35.6 1.5 6.1e-09 35.6 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB08598.1 - 2.9e-08 33.6 1.5 5.7e-08 32.6 0.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGB08598.1 - 1.3e-06 28.2 2.1 6.2e-06 26.0 0.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB08598.1 - 4.9e-06 26.4 3.9 1.1e-05 25.2 4.1 1.5 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGB08598.1 - 9.7e-06 25.4 4.8 2.3e-05 24.1 4.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB08598.1 - 2.2e-05 24.2 0.7 2.2e-05 24.2 0.7 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGB08598.1 - 0.00024 20.8 0.8 0.0012 18.6 0.3 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGB08598.1 - 0.0017 18.0 2.8 0.0017 18.0 2.8 2.2 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGB08598.1 - 0.0018 18.0 8.0 0.0035 17.0 3.8 2.8 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_9 PF13901.6 EGB08598.1 - 0.0031 17.5 0.3 0.0036 17.3 0.3 1.0 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zf-P11 PF03854.14 EGB08598.1 - 0.0041 16.7 2.4 0.32 10.7 1.3 2.2 2 0 0 2 2 2 1 P-11 zinc finger zf-RING_6 PF14835.6 EGB08598.1 - 0.014 15.3 0.3 0.014 15.3 0.3 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein RecR PF02132.15 EGB08598.1 - 0.02 14.5 0.8 6 6.5 0.1 2.2 2 0 0 2 2 2 0 RecR protein zf-Nse PF11789.8 EGB08598.1 - 0.02 14.7 1.6 0.021 14.6 0.1 1.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EGB08598.1 - 0.025 14.7 3.1 0.025 14.7 3.1 2.0 2 0 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 EGB08598.1 - 0.078 13.3 2.1 0.078 13.3 2.1 1.7 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.6 EGB08598.1 - 0.1 12.6 6.7 3.8 7.5 3.3 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 EGB08598.1 - 0.19 11.6 0.5 0.49 10.3 0.0 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif PHD PF00628.29 EGB08598.1 - 1.1 9.2 7.6 6.8 6.7 7.7 2.2 1 1 1 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.6 EGB08598.1 - 1.7 8.9 10.5 0.093 12.9 4.5 2.0 2 1 1 3 3 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EGB08598.1 - 1.9 8.7 10.6 19 5.5 10.6 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EGB08598.1 - 2.7 8.1 10.2 0.2 11.7 3.3 2.4 2 1 0 2 2 2 0 Zinc-finger CA_like PF10563.9 EGB08599.1 - 4.9e-57 192.8 2.2 6.1e-57 192.5 2.2 1.1 1 0 0 1 1 1 1 Putative carbonic anhydrase GFO_IDH_MocA PF01408.22 EGB08601.1 - 4.7e-20 72.6 0.0 1e-19 71.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HPP PF04982.13 EGB08601.1 - 7.4e-15 55.2 19.3 5.4e-14 52.4 19.3 2.6 1 0 0 1 1 1 1 HPP family NAD_binding_3 PF03447.16 EGB08601.1 - 0.027 15.1 0.0 0.07 13.8 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ham1p_like PF01725.16 EGB08603.1 - 4.8e-49 166.8 0.0 5.3e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF747 PF05346.11 EGB08604.1 - 1.7e-83 280.7 7.8 2.1e-83 280.4 7.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Ank_4 PF13637.6 EGB08605.1 - 7.7e-26 90.1 2.5 8.2e-07 29.5 0.6 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB08605.1 - 6.9e-20 71.4 1.5 1e-10 42.1 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB08605.1 - 2e-19 67.6 3.1 0.00015 22.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EGB08605.1 - 1.9e-17 62.8 9.1 0.0024 18.2 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGB08605.1 - 2.1e-16 59.8 8.2 0.00013 22.2 0.8 4.8 3 2 1 4 4 4 3 Ankyrin repeats (many copies) SPC12 PF06645.13 EGB08606.1 - 2.6e-20 72.3 4.0 3.8e-15 55.7 1.8 2.0 1 1 1 2 2 2 2 Microsomal signal peptidase 12 kDa subunit (SPC12) LapA_dom PF06305.11 EGB08606.1 - 0.093 12.6 2.8 4.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DnaJ PF00226.31 EGB08608.1 - 1.4e-13 50.7 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain DUF641 PF04859.12 EGB08608.1 - 0.0053 17.1 0.0 0.0079 16.5 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) SplA PF11132.8 EGB08608.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) TIG PF01833.24 EGB08609.1 - 0 1145.0 0.0 1e-13 51.1 0.0 52.1 53 2 0 53 53 53 44 IPT/TIG domain TIG_plexin PF17960.1 EGB08609.1 - 2.2e-73 242.3 0.0 0.37 10.8 0.0 42.5 49 0 0 49 49 49 16 TIG domain Ephrin_rec_like PF07699.13 EGB08609.1 - 3.9e-06 26.5 49.1 0.00015 21.5 4.0 6.9 5 2 2 7 7 7 4 Putative ephrin-receptor like IQ PF00612.27 EGB08610.1 - 0.00034 20.1 2.5 0.001 18.6 2.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif QLQ PF08880.11 EGB08610.1 - 0.24 11.2 0.9 0.4 10.5 0.2 1.7 2 0 0 2 2 2 0 QLQ Pox_Ag35 PF03286.14 EGB08611.1 - 0.042 13.6 1.3 0.056 13.2 1.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein EMP70 PF02990.16 EGB08612.1 - 1.3e-190 634.5 8.8 1.7e-190 634.1 8.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TPR_12 PF13424.6 EGB08613.1 - 2e-51 172.2 37.2 2.9e-15 56.3 2.9 4.6 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGB08613.1 - 1.1e-38 130.1 23.7 9.9e-09 34.8 0.3 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGB08613.1 - 5.7e-18 63.6 18.2 0.00046 20.0 0.2 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB08613.1 - 3.8e-14 51.6 11.6 0.01 16.0 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGB08613.1 - 8.3e-14 50.7 14.6 0.017 14.9 0.0 5.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB08613.1 - 4.7e-12 45.1 19.1 0.0023 17.9 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB08613.1 - 1.3e-06 28.7 13.9 0.091 13.6 0.3 6.0 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGB08613.1 - 3.9e-05 23.9 16.7 0.088 13.5 0.1 6.3 6 2 1 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB08613.1 - 8.2e-05 23.0 6.4 4.2 8.2 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Mob_Pre PF01076.19 EGB08613.1 - 0.0004 20.3 0.0 0.68 9.7 0.0 3.3 3 1 0 3 3 3 1 Plasmid recombination enzyme DUF4807 PF16065.5 EGB08613.1 - 0.0012 18.5 1.8 13 5.4 0.1 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4807) TPR_17 PF13431.6 EGB08613.1 - 0.0033 17.7 4.4 7.2 7.2 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB08613.1 - 0.0047 17.5 2.7 0.0047 17.5 2.7 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB08613.1 - 0.0087 15.5 1.5 0.022 14.2 0.5 1.6 1 1 0 1 1 1 1 MalT-like TPR region XdhC_CoxI PF02625.16 EGB08613.1 - 0.02 15.1 2.6 22 5.3 0.0 4.1 1 1 3 4 4 4 0 XdhC and CoxI family pKID PF02173.17 EGB08613.1 - 0.18 11.3 0.3 13 5.4 0.0 3.3 3 0 0 3 3 3 0 pKID domain YlmH_RBD PF17774.1 EGB08613.1 - 0.19 12.0 0.2 2.3 8.6 0.0 2.7 3 1 0 3 3 3 0 Putative RNA-binding domain in YlmH TPR_19 PF14559.6 EGB08613.1 - 0.84 10.2 11.6 2.5 8.7 1.3 4.3 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB08613.1 - 1.2 8.8 13.6 3.7 7.3 0.1 4.2 5 0 0 5 5 5 0 TPR repeat Rhodanese_C PF12368.8 EGB08614.1 - 6.2e-11 42.5 9.0 6.2e-11 42.5 9.0 2.2 2 1 0 2 2 2 1 Rhodanase C-terminal UPF0176_N PF17773.1 EGB08614.1 - 7.5e-08 32.6 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 EGB08614.1 - 0.0033 17.9 0.0 0.017 15.6 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain Steroid_dh PF02544.16 EGB08615.1 - 3.5e-19 69.3 0.8 3.5e-19 69.3 0.8 2.6 3 1 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase RBP_receptor PF14752.6 EGB08615.1 - 6.5e-15 54.7 9.5 7.9e-13 47.8 3.7 2.2 1 1 1 2 2 2 2 Retinol binding protein receptor YchF-GTPase_C PF06071.13 EGB08616.1 - 2.6e-21 75.6 0.0 4.7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGB08616.1 - 1.8e-09 37.6 0.0 3.6e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB08616.1 - 2.3e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Pkinase PF00069.25 EGB08617.1 - 1.2e-51 175.6 0.0 1.3e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08617.1 - 2.1e-19 69.9 0.0 2.3e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB08617.1 - 4.9e-06 25.6 0.0 6.5e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB08617.1 - 7.9e-05 22.1 0.2 0.00012 21.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB08617.1 - 0.00034 20.6 0.3 0.00057 19.9 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB08617.1 - 0.00034 20.0 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EGB08617.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C3HC4_3 PF13920.6 EGB08618.1 - 3.1e-12 46.2 7.6 3.1e-12 46.2 7.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 EGB08618.1 - 3.7e-07 30.1 2.1 3.7e-07 30.1 2.1 1.9 2 0 0 2 2 1 1 PA domain LRR_6 PF13516.6 EGB08618.1 - 1.4e-06 27.9 8.1 0.72 10.1 0.0 6.4 7 0 0 7 7 7 2 Leucine Rich repeat zf-C3HC4_2 PF13923.6 EGB08618.1 - 4.3e-06 26.5 8.2 1e-05 25.3 8.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.7 EGB08618.1 - 5.7e-06 26.6 1.3 0.2 12.1 0.4 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) zf-C3HC4 PF00097.25 EGB08618.1 - 8.9e-06 25.5 6.6 2.2e-05 24.3 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB08618.1 - 3.8e-05 23.4 8.6 8.3e-05 22.4 8.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 LRR_1 PF00560.33 EGB08618.1 - 0.00015 21.8 2.0 7.1 7.6 0.2 5.6 6 0 0 6 6 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EGB08618.1 - 0.00024 20.8 2.3 0.014 15.1 0.1 3.0 2 0 0 2 2 2 1 Leucine rich repeat zf-RING_2 PF13639.6 EGB08618.1 - 0.00051 20.3 8.4 0.00051 20.3 8.4 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 EGB08618.1 - 0.0012 18.7 8.3 0.0035 17.3 8.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB08618.1 - 0.0028 17.6 3.4 0.0066 16.4 3.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGB08618.1 - 0.058 13.2 8.5 0.18 11.7 8.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGB08618.1 - 0.31 11.2 6.4 0.66 10.2 6.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGB08618.1 - 2.4 8.1 5.8 5.9 6.8 5.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ribosomal_L15e PF00827.17 EGB08619.1 - 3.4e-92 307.4 10.9 3.9e-92 307.2 10.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 DNA_pol_A PF00476.20 EGB08620.1 - 0.17 10.9 0.1 0.24 10.4 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase family A TB2_DP1_HVA22 PF03134.19 EGB08621.1 - 3.7e-21 74.8 5.1 4.4e-21 74.6 5.1 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family AMP-binding PF00501.28 EGB08621.1 - 0.093 11.3 0.2 0.099 11.2 0.2 1.2 1 0 0 1 1 1 0 AMP-binding enzyme zf-C3HC4_3 PF13920.6 EGB08622.1 - 1.5e-12 47.2 6.4 2.9e-12 46.2 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB08622.1 - 2.3e-08 33.8 8.0 4.2e-08 32.9 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TauD PF02668.16 EGB08622.1 - 2.9e-05 24.0 0.2 0.00011 22.2 0.1 1.9 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family zf-RING_2 PF13639.6 EGB08622.1 - 0.00014 22.1 7.7 0.00027 21.2 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGB08622.1 - 0.00027 20.8 8.2 0.00049 19.9 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB08622.1 - 0.00073 19.4 7.2 0.0014 18.6 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGB08622.1 - 0.05 13.4 7.8 0.092 12.6 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGB08622.1 - 1.8 8.4 5.0 5.5 6.9 5.0 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGB08622.1 - 2.9 8.1 8.5 0.85 9.8 5.2 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 DNA_pol_A_exo1 PF01612.20 EGB08624.1 - 2.1e-07 30.8 0.1 0.0077 16.0 0.3 2.2 1 1 1 2 2 2 2 3'-5' exonuclease UPF0029 PF01205.19 EGB08624.1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 IL17_R_N PF15037.6 EGB08624.1 - 0.073 12.0 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region MAP70 PF07058.11 EGB08625.1 - 0.056 12.2 0.1 0.081 11.7 0.1 1.3 1 0 0 1 1 1 0 Microtubule-associated protein 70 Costars PF14705.6 EGB08626.1 - 9.8e-24 83.3 0.0 1.1e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Costars MtN3_slv PF03083.16 EGB08627.1 - 3.7e-32 110.2 0.4 5.3e-20 71.2 0.2 2.1 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Epimerase PF01370.21 EGB08628.1 - 8.1e-08 32.0 0.1 1.4e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB08628.1 - 1.4e-07 31.6 0.1 3.5e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EGB08628.1 - 0.00027 20.5 0.0 0.00055 19.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EGB08628.1 - 0.0006 18.9 0.0 0.00089 18.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGB08628.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EGB08628.1 - 0.0018 17.9 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Ion_trans PF00520.31 EGB08628.1 - 0.0097 15.2 0.2 0.015 14.6 0.2 1.2 1 0 0 1 1 1 1 Ion transport protein PsbK PF02533.15 EGB08628.1 - 0.086 13.0 0.4 0.2 11.8 0.4 1.5 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component KR PF08659.10 EGB08628.1 - 0.092 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 EGB08628.1 - 0.25 10.7 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EGB08628.1 - 0.42 10.1 2.4 2.6 7.5 0.2 2.3 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase LRR_4 PF12799.7 EGB08630.1 - 1.2e-38 130.4 26.5 0.00085 19.7 0.4 12.2 6 2 4 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB08630.1 - 1.7e-26 91.7 18.2 0.0017 18.1 0.1 9.5 2 2 10 13 13 13 12 Leucine rich repeat LRR_1 PF00560.33 EGB08630.1 - 1.8e-07 30.7 52.6 22 6.1 0.1 18.9 21 0 0 21 21 21 1 Leucine Rich Repeat LRR_5 PF13306.6 EGB08630.1 - 0.00018 21.5 0.0 4.5 7.2 0.0 4.6 1 1 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) DUF1397 PF07165.11 EGB08630.1 - 0.62 9.4 7.1 1.2 8.5 0.2 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1397) SUZ PF12752.7 EGB08631.1 - 1.4e-06 28.9 0.9 1.4e-06 28.9 0.9 2.8 3 1 0 3 3 3 1 SUZ domain Glyco_hydro_43 PF04616.14 EGB08634.1 - 0.026 13.9 0.3 0.041 13.2 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 PP2C PF00481.21 EGB08635.1 - 5.1e-19 68.9 0.0 1.1e-18 67.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 EGB08635.1 - 8.3e-11 41.7 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PP2C_2 PF13672.6 EGB08635.1 - 0.00033 20.4 4.1 0.00033 20.4 4.1 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 EGB08635.1 - 0.0043 16.4 0.0 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FKBP_C PF00254.28 EGB08636.1 - 7.3e-20 71.1 0.0 7.9e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PilJ PF13675.6 EGB08637.1 - 0.049 13.7 4.6 0.5 10.4 0.5 3.5 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term MlaC PF05494.12 EGB08637.1 - 0.84 9.4 4.8 0.59 9.9 0.1 2.3 2 0 0 2 2 2 0 MlaC protein Ion_trans PF00520.31 EGB08638.1 - 0.00014 21.2 0.4 0.00015 21.1 0.4 1.1 1 0 0 1 1 1 1 Ion transport protein PHD PF00628.29 EGB08639.1 - 1e-27 95.8 79.1 2.3e-08 33.8 6.1 7.9 8 1 0 8 8 8 6 PHD-finger zf-HC5HC2H PF13771.6 EGB08639.1 - 5e-20 71.5 7.6 3e-11 43.4 0.2 6.6 4 1 2 6 6 6 3 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGB08639.1 - 3.1e-18 66.0 7.8 4.9e-13 49.2 0.9 6.2 4 1 2 6 6 6 2 PHD-zinc-finger like domain PHD_2 PF13831.6 EGB08639.1 - 9.6e-09 34.7 0.4 9.6e-09 34.7 0.4 6.8 6 1 0 6 6 6 2 PHD-finger PhnA_Zn_Ribbon PF08274.12 EGB08639.1 - 2.2 8.3 0.0 2.2 8.3 0.0 5.8 7 2 1 8 8 8 0 PhnA Zinc-Ribbon TFIIA PF03153.13 EGB08639.1 - 2.5 8.0 10.2 3.8 7.4 10.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF218 PF02698.17 EGB08640.1 - 1.5e-21 76.8 0.0 2.1e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Ras PF00071.22 EGB08641.1 - 2.5e-41 141.0 0.0 3.4e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB08641.1 - 8.4e-22 77.6 0.1 1.5e-21 76.8 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB08641.1 - 5.2e-12 45.6 0.0 5.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGB08641.1 - 2.2e-06 27.4 0.0 2.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB08641.1 - 0.024 14.0 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FAD_binding_9 PF08021.11 EGB08641.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Sulfatase PF00884.23 EGB08642.1 - 5.6e-62 209.9 0.0 8.8e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB08642.1 - 1.2e-06 28.4 0.3 1.7e-05 24.6 0.3 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 EGB08642.1 - 0.042 13.7 0.2 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function RNA_pol_Rpc4 PF05132.14 EGB08642.1 - 0.24 11.8 3.9 0.86 10.0 3.9 1.9 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.8 EGB08642.1 - 0.55 9.0 4.0 0.89 8.3 4.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LRR_4 PF12799.7 EGB08643.1 - 0.0045 17.4 1.6 1.2 9.7 0.8 3.7 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB08643.1 - 0.049 13.4 0.7 0.55 10.0 0.1 2.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 EGB08646.1 - 3.2e-07 30.0 1.6 0.22 12.2 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.6 EGB08646.1 - 2.2e-06 27.4 6.6 4.4e-06 26.4 1.6 3.1 2 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EGB08646.1 - 2.3e-06 27.9 2.2 0.0019 18.5 0.5 3.4 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB08646.1 - 0.031 14.3 0.8 8.2 6.8 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Lipase_GDSL_2 PF13472.6 EGB08647.1 - 1.5e-26 93.9 0.4 1.9e-26 93.5 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB08647.1 - 1e-12 48.4 0.0 1.6e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amino_oxidase PF01593.24 EGB08648.1 - 3e-07 30.1 0.1 1e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase IMUP PF15761.5 EGB08648.1 - 0.17 12.6 8.3 0.4 11.4 8.3 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EGB08648.1 - 0.32 10.6 11.1 0.5 9.9 11.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dak1 PF02733.17 EGB08648.1 - 4.2 6.2 5.7 0.23 10.3 0.5 1.5 2 0 0 2 2 2 0 Dak1 domain CS PF04969.16 EGB08649.1 - 0.00016 22.6 0.0 0.00028 21.8 0.0 1.4 1 0 0 1 1 1 1 CS domain Ank PF00023.30 EGB08649.1 - 0.0026 18.1 0.1 0.0075 16.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EGB08649.1 - 0.0028 17.9 0.1 0.011 16.0 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB08649.1 - 0.014 15.9 0.1 0.037 14.6 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB08649.1 - 0.039 14.5 0.1 0.23 12.2 0.1 2.4 1 0 0 1 1 1 0 Ankyrin repeat HTH_32 PF13565.6 EGB08649.1 - 0.37 11.4 4.9 0.21 12.2 0.2 3.2 2 0 0 2 2 2 0 Homeodomain-like domain Aldo_ket_red PF00248.21 EGB08650.1 - 6.3e-11 42.0 0.0 7.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Exostosin PF03016.15 EGB08651.1 - 2.4e-17 63.1 0.0 3.5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Sulfotransfer_4 PF17784.1 EGB08651.1 - 0.00064 19.6 0.0 0.45 10.3 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase domain Pkinase PF00069.25 EGB08652.1 - 8.2e-57 192.5 0.0 1.2e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EGB08652.1 - 3.4e-39 132.8 0.3 2.5e-18 65.9 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGB08652.1 - 3.8e-29 101.8 0.0 6.1e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB08652.1 - 0.028 13.7 0.0 0.086 12.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Nsp2a_N PF17896.1 EGB08652.1 - 0.055 12.6 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Na_H_Exchanger PF00999.21 EGB08653.1 - 3e-24 85.6 17.7 3.9e-24 85.2 17.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1127 PF06568.11 EGB08653.1 - 0.0054 16.4 0.2 0.016 14.9 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) Cyanate_lyase PF02560.14 EGB08654.1 - 2.4e-28 97.8 0.1 3.2e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Vps62 PF06101.11 EGB08654.1 - 0.002 16.5 0.0 0.0025 16.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 MFS_5 PF05631.14 EGB08654.1 - 0.045 12.7 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM Sel1 PF08238.12 EGB08656.1 - 7.8e-25 86.8 22.0 4.9e-07 30.2 0.0 8.3 8 0 0 8 8 8 4 Sel1 repeat zf-MYND PF01753.18 EGB08656.1 - 0.014 15.5 0.9 0.014 15.5 0.9 3.0 2 1 1 3 3 3 0 MYND finger CAP_N PF01213.19 EGB08656.1 - 0.13 11.7 1.0 0.2 11.1 1.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Fer2_3 PF13085.6 EGB08656.1 - 0.25 11.4 2.6 0.53 10.3 2.6 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TPR_12 PF13424.6 EGB08656.1 - 1.5 9.2 6.8 3.7 7.9 0.1 4.4 4 2 2 6 6 6 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 EGB08656.1 - 4.1 7.8 13.6 12 6.3 13.6 1.9 1 0 0 1 1 1 0 Ring finger domain TPR_2 PF07719.17 EGB08656.1 - 5.2 7.4 15.0 5.1 7.5 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat YidD PF01809.18 EGB08657.1 - 4.8e-23 80.8 0.1 5.2e-23 80.7 0.1 1.0 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor cobW PF02492.19 EGB08658.1 - 1.1e-55 187.9 0.2 1.4e-55 187.6 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB08658.1 - 1.9e-17 62.9 0.0 3.9e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGB08658.1 - 0.00051 20.0 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EGB08658.1 - 0.00058 19.0 0.0 0.0022 17.1 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein GTP_EFTU PF00009.27 EGB08658.1 - 0.0049 16.4 0.5 0.95 9.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGB08658.1 - 0.0058 17.0 0.1 0.0099 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 EGB08658.1 - 0.025 14.6 0.1 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGB08658.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EGB08658.1 - 0.04 13.7 0.0 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPgrasp_N PF18130.1 EGB08658.1 - 0.045 14.3 0.1 2.3 8.8 0.0 2.8 2 1 1 3 3 2 0 ATP-grasp N-terminal domain TrwB_AAD_bind PF10412.9 EGB08658.1 - 0.053 12.4 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 EGB08658.1 - 0.063 13.0 0.0 20 4.9 0.0 3.2 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 EGB08658.1 - 0.07 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EGB08658.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGB08658.1 - 0.079 13.5 1.1 0.24 11.9 0.1 2.1 1 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGB08658.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGB08658.1 - 0.093 12.5 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EGB08658.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGB08658.1 - 0.15 12.3 0.1 0.97 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGB08658.1 - 0.18 12.3 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGB08658.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Methyltransf_11 PF08241.12 EGB08659.1 - 2.1e-05 25.1 0.0 2.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB08659.1 - 0.00061 19.2 0.0 0.00065 19.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGB08659.1 - 0.0013 19.4 0.0 0.0028 18.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB08659.1 - 0.015 15.1 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EGB08659.1 - 0.13 13.3 0.1 0.3 12.2 0.1 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Ribosomal_L19 PF01245.20 EGB08660.1 - 2.1e-43 146.8 0.3 2.3e-43 146.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 MG2 PF01835.19 EGB08660.1 - 1.1e-05 25.8 0.0 1.3e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 MG2 domain EF-hand_6 PF13405.6 EGB08661.1 - 2.8e-05 23.7 0.0 0.057 13.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB08661.1 - 2.9e-05 23.3 0.0 0.0037 16.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 EGB08661.1 - 0.0015 18.0 0.0 0.06 12.9 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGB08661.1 - 0.0049 17.3 0.0 0.0083 16.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair Trm112p PF03966.16 EGB08662.1 - 4.6e-08 33.5 0.0 6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein Tyrosinase PF00264.20 EGB08663.1 - 3.4e-09 37.3 1.1 0.00055 20.3 0.9 2.2 2 0 0 2 2 2 2 Common central domain of tyrosinase Kelch_3 PF13415.6 EGB08663.1 - 8.6e-07 29.1 9.8 0.043 14.1 0.3 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Ank_2 PF12796.7 EGB08663.1 - 0.015 15.8 0.0 0.63 10.7 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Kelch_5 PF13854.6 EGB08663.1 - 0.024 14.6 2.4 0.034 14.1 0.1 2.6 3 0 0 3 3 3 0 Kelch motif Ank_5 PF13857.6 EGB08663.1 - 0.032 14.5 2.5 5.5 7.4 0.0 3.9 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Kelch_6 PF13964.6 EGB08663.1 - 0.034 14.5 0.0 5.6 7.4 0.0 3.2 2 1 1 3 3 3 0 Kelch motif Kelch_2 PF07646.15 EGB08663.1 - 0.089 12.8 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Ank_4 PF13637.6 EGB08663.1 - 0.098 13.3 0.0 39 5.0 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08663.1 - 0.16 12.6 0.8 28 5.7 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat Kinesin PF00225.23 EGB08664.1 - 1.6e-69 234.4 0.0 2.6e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB08664.1 - 2.1e-13 50.5 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Pro_dh PF01619.18 EGB08665.1 - 1.2e-77 261.4 0.1 1.2e-76 258.1 0.1 1.9 1 1 0 1 1 1 1 Proline dehydrogenase M16C_assoc PF08367.11 EGB08666.1 - 0.099 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase M16C associated TPR_2 PF07719.17 EGB08667.1 - 0.00075 19.4 21.4 0.078 13.1 0.2 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB08667.1 - 0.0018 18.4 5.8 1.6 9.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3808 PF10300.9 EGB08667.1 - 0.046 12.5 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_1 PF00515.28 EGB08667.1 - 0.059 13.2 0.1 0.059 13.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Dus PF01207.17 EGB08668.1 - 4.6e-52 177.1 0.2 2.7e-51 174.5 0.2 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 EGB08668.1 - 1.3e-06 28.0 1.3 1.6e-06 27.7 0.8 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase TMP-TENI PF02581.17 EGB08668.1 - 0.00024 20.5 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase IMPDH PF00478.25 EGB08668.1 - 0.00027 20.0 3.2 0.00053 19.1 3.2 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EGB08668.1 - 0.002 17.6 0.0 0.004 16.6 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EGB08668.1 - 0.022 14.1 0.3 0.037 13.3 0.3 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Pkinase PF00069.25 EGB08669.1 - 6.8e-40 137.1 0.0 7.5e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08669.1 - 1.5e-13 50.6 0.0 1.7e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB08669.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB08669.1 - 0.00026 21.0 1.0 0.00096 19.1 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB08669.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGB08669.1 - 0.094 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NAD_binding_8 PF13450.6 EGB08671.1 - 2.4e-11 43.7 0.4 2.4e-11 43.7 0.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Methyltransf_23 PF13489.6 EGB08671.1 - 2.1e-08 34.2 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Amino_oxidase PF01593.24 EGB08671.1 - 2.9e-08 33.4 2.9 0.00098 18.5 0.4 3.8 3 1 0 3 3 3 2 Flavin containing amine oxidoreductase Methyltransf_11 PF08241.12 EGB08671.1 - 3.6e-07 30.8 0.7 3.6e-07 30.8 0.7 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB08671.1 - 4e-07 30.6 0.8 4e-07 30.6 0.8 3.0 3 0 0 3 3 3 1 Methyltransferase domain MetW PF07021.12 EGB08671.1 - 0.00036 20.2 0.2 0.00079 19.1 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Pyr_redox_2 PF07992.14 EGB08671.1 - 0.0021 17.3 0.3 0.0044 16.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CMAS PF02353.20 EGB08671.1 - 0.0035 16.7 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pyr_redox PF00070.27 EGB08671.1 - 0.0046 17.5 0.4 0.01 16.4 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB08671.1 - 0.022 13.4 0.8 0.033 12.9 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_31 PF13847.6 EGB08671.1 - 0.031 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 EGB08671.1 - 0.045 13.4 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 EGB08671.1 - 0.059 14.1 0.1 0.22 12.3 0.1 2.1 1 0 0 1 1 1 0 Methyltransferase domain Thi4 PF01946.17 EGB08671.1 - 0.099 11.9 0.8 0.17 11.1 0.8 1.3 1 0 0 1 1 1 0 Thi4 family DUF4140 PF13600.6 EGB08671.1 - 0.13 12.7 1.2 30 5.1 0.3 2.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SHMT PF00464.19 EGB08672.1 - 1.1e-171 570.9 0.0 1.2e-171 570.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EGB08672.1 - 6.2e-06 25.7 0.0 9.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Mpv17_PMP22 PF04117.12 EGB08673.1 - 6.2e-11 42.4 0.1 2.1e-10 40.7 0.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family NopRA1 PF16201.5 EGB08674.1 - 6.8e-16 58.5 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Clat_adaptor_s PF01217.20 EGB08675.1 - 9.7e-49 165.0 3.5 2.4e-26 92.4 0.8 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain FKBP_C PF00254.28 EGB08677.1 - 6.4e-10 39.2 0.0 8.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase adh_short PF00106.25 EGB08678.1 - 3.5e-25 88.6 0.0 9.7e-21 74.1 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGB08678.1 - 9e-09 35.2 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB08678.1 - 0.00075 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 KR domain GTP_EFTU PF00009.27 EGB08679.1 - 2.1e-47 161.2 0.0 2.6e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGB08679.1 - 6.5e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGB08679.1 - 0.0049 16.9 0.0 0.93 9.5 0.0 2.2 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 EGB08679.1 - 0.023 14.2 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGB08679.1 - 0.023 14.6 0.0 4.4 7.2 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase zf-rbx1 PF12678.7 EGB08680.1 - 9.7e-16 57.8 5.2 5.7e-09 36.1 0.7 2.1 2 0 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGB08680.1 - 1.8e-06 28.2 8.9 2.7e-06 27.6 0.8 2.6 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB08680.1 - 9.6e-06 25.4 6.0 0.00021 21.0 0.6 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGB08680.1 - 7.3e-05 22.7 5.9 0.00027 20.9 2.9 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EGB08680.1 - 0.00096 19.0 3.4 0.03 14.2 0.4 2.4 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGB08680.1 - 0.0023 18.0 3.6 0.0069 16.5 1.1 2.2 2 0 0 2 2 2 1 RING-variant domain zf-C3HC4_3 PF13920.6 EGB08680.1 - 0.0085 15.9 5.9 0.031 14.1 0.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB08680.1 - 0.036 14.1 5.3 2.3 8.3 0.3 2.7 2 2 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 EGB08680.1 - 0.043 14.1 0.3 0.043 14.1 0.3 1.8 2 0 0 2 2 2 0 RING-like domain Prok-RING_4 PF14447.6 EGB08680.1 - 0.052 13.4 5.2 0.16 11.9 0.3 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGB08680.1 - 0.096 12.7 5.4 1.1 9.3 0.2 2.5 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGB08680.1 - 2.2 8.1 6.5 11 5.9 0.4 3.1 3 0 0 3 3 3 0 RING-like zinc finger ubiquitin PF00240.23 EGB08681.1 - 1.1e-24 85.9 0.1 1.2e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB08681.1 - 8.7e-09 35.1 0.3 9.1e-09 35.0 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB08681.1 - 0.0007 20.0 0.0 0.00098 19.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB08681.1 - 0.0024 17.7 0.0 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGB08681.1 - 0.0049 17.2 0.0 0.0059 16.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TmoB PF06234.12 EGB08681.1 - 0.063 13.4 0.1 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) DUF2407 PF10302.9 EGB08681.1 - 0.069 13.7 0.0 0.082 13.5 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PRCC PF10253.9 EGB08682.1 - 2.5e-11 44.8 5.4 2.5e-11 44.8 5.4 1.8 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting ALF PF03752.13 EGB08682.1 - 0.017 15.1 0.8 0.017 15.1 0.8 2.4 3 0 0 3 3 3 0 Short repeats of unknown function Inositol_P PF00459.25 EGB08683.1 - 1.5e-49 169.0 3.5 1.9e-49 168.6 3.5 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PQQ_3 PF13570.6 EGB08683.1 - 0.26 11.8 3.3 1.7 9.2 0.4 3.0 2 0 0 2 2 2 0 PQQ-like domain Pyr_redox_2 PF07992.14 EGB08685.1 - 4.4e-54 183.7 2.1 5.6e-54 183.4 2.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB08685.1 - 2.5e-27 95.3 0.2 5.4e-27 94.2 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB08685.1 - 1e-11 45.2 0.6 4.9e-11 43.0 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB08685.1 - 0.001 18.3 3.8 0.001 18.3 3.8 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGB08685.1 - 0.044 13.1 4.1 0.073 12.4 4.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 EGB08685.1 - 0.059 12.5 0.1 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EGB08685.1 - 0.061 12.4 7.1 0.027 13.6 4.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGB08685.1 - 0.15 12.3 5.7 8.1 6.8 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain RNA_pol_Rbc25 PF08292.12 EGB08687.1 - 5.6e-25 88.1 0.0 7.6e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EGB08687.1 - 5.3e-15 55.5 0.1 8e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Ribosomal_L4 PF00573.22 EGB08688.1 - 1.2e-40 139.3 0.0 1.2e-40 139.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGB08688.1 - 1.1e-27 95.9 1.7 1.1e-27 95.9 1.7 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain RRM_1 PF00076.22 EGB08689.1 - 2.5e-20 72.1 0.0 2.9e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.26 EGB08690.1 - 2.7e-14 53.3 0.0 4.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGB08690.1 - 6e-05 23.3 0.1 0.0042 17.4 0.1 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain REC114-like PF15165.6 EGB08690.1 - 0.082 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Myosin_head PF00063.21 EGB08691.1 - 9.6e-112 374.4 0.0 1.2e-110 370.8 0.0 2.5 1 1 0 1 1 1 1 Myosin head (motor domain) PH PF00169.29 EGB08691.1 - 9.2e-15 55.0 0.0 1.5e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 PH domain WW PF00397.26 EGB08691.1 - 2.4e-10 40.3 5.4 1.3e-09 38.0 4.1 2.4 2 0 0 2 2 2 1 WW domain PH_11 PF15413.6 EGB08691.1 - 7e-05 23.2 0.7 0.0002 21.8 0.7 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EGB08691.1 - 0.0027 18.0 0.1 0.0078 16.5 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain Zeta_toxin PF06414.12 EGB08691.1 - 0.0083 15.4 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EGB08691.1 - 0.08 13.3 0.0 0.08 13.3 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain MTS PF05175.14 EGB08692.1 - 3.1e-09 36.6 0.0 6.4e-07 29.1 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB08692.1 - 1.3e-05 25.9 0.5 4.4e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGB08692.1 - 0.0001 23.3 0.0 0.00041 21.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGB08692.1 - 0.0012 18.3 0.1 0.0055 16.1 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGB08692.1 - 0.0039 17.8 1.6 0.018 15.7 0.1 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB08692.1 - 0.0064 17.2 0.0 0.017 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EGB08692.1 - 0.054 13.2 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) adh_short PF00106.25 EGB08692.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Thiolase_N PF00108.23 EGB08693.1 - 3.5e-68 229.8 1.1 2e-67 227.3 0.5 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGB08693.1 - 5.1e-39 132.7 0.0 1.1e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGB08693.1 - 3.5e-06 26.8 3.7 2.3e-05 24.1 0.7 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EGB08693.1 - 0.0064 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) WD40 PF00400.32 EGB08694.1 - 1.8e-06 28.5 3.2 0.0024 18.7 0.7 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ERCC3_RAD25_C PF16203.5 EGB08695.1 - 3.8e-100 334.2 0.0 6e-100 333.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGB08695.1 - 2.7e-30 105.1 0.0 5.9e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB08695.1 - 7.7e-15 55.3 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGB08695.1 - 5.1e-10 38.6 0.0 8.2e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB08695.1 - 7.1e-09 36.0 0.0 1.6e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EGB08695.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase GlcNAc PF11397.8 EGB08696.1 - 3e-73 247.3 0.0 3.6e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.6 EGB08696.1 - 0.039 13.9 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 WD40 PF00400.32 EGB08697.1 - 2.7e-08 34.3 0.1 0.28 12.1 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08697.1 - 2.3e-06 27.8 0.0 0.39 11.0 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 EGB08697.1 - 0.0088 16.0 0.0 4.6 7.3 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein domain (DUF2415) PI3_PI4_kinase PF00454.27 EGB08698.1 - 9.4e-25 87.8 0.0 8.6e-18 65.0 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase AMP-binding PF00501.28 EGB08699.1 - 9.3e-80 268.3 0.4 1.2e-79 268.0 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB08699.1 - 1.7e-17 64.1 0.2 1.2e-16 61.4 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Marek_SORF3 PF07153.11 EGB08699.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein ketoacyl-synt PF00109.26 EGB08700.1 - 3e-54 184.2 1.1 5e-54 183.5 1.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB08700.1 - 1.2e-26 93.0 2.1 2.3e-26 92.1 2.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGB08700.1 - 2.5e-05 24.7 0.0 4.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Pkinase PF00069.25 EGB08701.1 - 8.7e-48 163.0 0.0 9.7e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08701.1 - 1.3e-18 67.3 0.0 1.6e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB08701.1 - 0.00027 19.8 0.0 0.00035 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB08701.1 - 0.00029 20.3 0.0 0.00093 18.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGB08701.1 - 0.002 17.5 0.0 0.0062 15.9 0.0 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB08701.1 - 0.0026 17.7 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF5397 PF17375.2 EGB08701.1 - 0.19 11.5 0.2 3.2 7.5 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5397) Sulfotransfer_2 PF03567.14 EGB08702.1 - 0.0037 17.2 0.0 2.1 8.2 0.0 2.7 2 1 0 2 2 2 2 Sulfotransferase family Methyltransf_11 PF08241.12 EGB08703.1 - 9.9e-12 45.4 0.1 1.4e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB08703.1 - 1e-09 39.0 0.0 1.5e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB08703.1 - 3.2e-05 23.8 0.0 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB08703.1 - 0.072 12.9 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.6 EGB08705.1 - 1.2e-09 38.2 1.1 1.2e-08 35.0 0.6 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGB08705.1 - 0.0023 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EGB08705.1 - 0.0073 15.6 0.4 0.033 13.4 0.1 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB08705.1 - 0.14 12.8 0.1 0.62 10.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB08705.1 - 1.6 8.2 10.0 48 3.4 10.0 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase CAP_C PF08603.11 EGB08706.1 - 1.3e-50 171.1 2.6 1.7e-50 170.7 2.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 EGB08706.1 - 9.6e-39 133.7 0.1 1.3e-38 133.3 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 EGB08706.1 - 1.7e-05 24.5 3.1 2.8e-05 23.8 3.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF3060 PF11259.8 EGB08706.1 - 1.1 9.0 4.4 4.3 7.1 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3060) HA PF03457.14 EGB08707.1 - 3.4e-32 110.6 3.6 3.2e-09 37.0 0.0 4.1 5 0 0 5 5 5 3 Helicase associated domain Methyltransf_21 PF05050.12 EGB08707.1 - 1.6e-07 31.6 0.4 1.7e-06 28.1 0.4 2.1 1 1 0 1 1 1 1 Methyltransferase FkbM domain U3_assoc_6 PF08640.11 EGB08708.1 - 1.7e-13 50.4 0.0 1.5e-12 47.4 0.0 2.5 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 DUF3675 PF12428.8 EGB08708.1 - 0.31 11.6 2.3 25 5.4 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) TPR_14 PF13428.6 EGB08708.1 - 2.6 9.1 33.5 0.36 11.8 0.6 7.0 4 1 2 6 6 6 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGB08709.1 - 9e-36 122.3 4.9 1.1e-10 42.0 0.2 2.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08709.1 - 9.4e-21 73.9 6.6 3.1e-05 24.4 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB08709.1 - 2.2e-17 62.9 2.8 1.4e-06 28.5 0.1 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08709.1 - 1e-15 56.2 0.6 0.039 14.5 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EGB08709.1 - 1.7e-13 50.3 5.8 0.007 16.8 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat FG-GAP_2 PF14312.6 EGB08710.1 - 2.7e-92 302.9 65.6 2e-15 56.8 6.8 7.1 7 0 0 7 7 7 7 FG-GAP repeat BNR_2 PF13088.6 EGB08710.1 - 1.5e-09 37.6 1.1 0.00012 21.5 0.1 2.2 1 1 0 2 2 2 2 BNR repeat-like domain Sortilin-Vps10 PF15902.5 EGB08710.1 - 1.4e-08 34.0 5.3 0.0043 15.9 0.1 3.2 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 EGB08710.1 - 0.0005 19.7 25.4 0.21 11.7 0.7 6.1 5 0 0 5 5 5 4 BNR/Asp-box repeat ImmE5 PF11480.8 EGB08710.1 - 0.1 13.1 2.1 11 6.5 0.0 3.7 3 1 1 4 4 4 0 Colicin-E5 Imm protein Cohesin_HEAT PF12765.7 EGB08711.1 - 3e-09 37.0 2.7 1.8e-06 28.1 0.2 2.6 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion Nipped-B_C PF12830.7 EGB08711.1 - 0.0074 16.2 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Ank_2 PF12796.7 EGB08712.1 - 1.8e-22 79.7 4.2 2.2e-10 41.0 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08712.1 - 1.5e-20 73.3 7.8 6.9e-08 32.9 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB08712.1 - 3.7e-17 62.2 14.9 7e-05 23.0 0.1 5.4 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08712.1 - 1.7e-13 49.4 8.7 0.0074 16.7 0.0 6.4 5 1 1 6 6 6 3 Ankyrin repeat Ank PF00023.30 EGB08712.1 - 9.7e-08 32.1 21.0 1.7 9.3 0.0 6.7 6 1 0 6 6 6 5 Ankyrin repeat Aldose_epim PF01263.20 EGB08713.1 - 1.8e-71 240.9 0.0 2.3e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Cupin_4 PF08007.12 EGB08714.1 - 2e-16 60.4 0.0 3.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein GST_N_3 PF13417.6 EGB08714.1 - 2.8e-14 53.3 0.0 6.9e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ephrin_rec_like PF07699.13 EGB08714.1 - 1.8e-10 40.4 35.8 4.8e-08 32.6 9.3 9.6 6 2 6 12 12 12 7 Putative ephrin-receptor like GST_N_2 PF13409.6 EGB08714.1 - 2.1e-10 40.7 0.0 5.8e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain dCache_1 PF02743.18 EGB08714.1 - 7.4e-08 32.5 0.4 2.4e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Cache domain Glutaredoxin PF00462.24 EGB08714.1 - 0.00052 20.2 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin AraC_binding PF02311.19 EGB08714.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain GST_C PF00043.25 EGB08714.1 - 0.099 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB08714.1 - 0.14 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Rubis-subs-bind PF09273.11 EGB08714.1 - 0.16 12.7 0.1 0.4 11.4 0.1 1.7 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding zf-MYND PF01753.18 EGB08715.1 - 1.2e-11 44.5 16.2 1.5e-11 44.2 16.2 1.1 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 EGB08715.1 - 0.14 10.0 3.4 0.14 10.0 3.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 EGB08715.1 - 0.14 12.4 10.3 0.25 11.7 10.3 1.4 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Fer4_4 PF12800.7 EGB08715.1 - 0.2 12.2 8.0 9.7 7.0 4.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain zf-ribbon_3 PF13248.6 EGB08715.1 - 0.54 9.8 6.9 7.9 6.0 2.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Asp_Arg_Hydrox PF05118.15 EGB08716.1 - 5.8e-33 113.9 0.1 6.4e-33 113.8 0.1 1.0 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 EGB08716.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cupin domain PH_6 PF15406.6 EGB08717.1 - 2.9e-05 24.3 0.0 0.0082 16.4 0.0 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EGB08717.1 - 0.00044 20.7 0.0 0.014 15.9 0.0 3.3 5 0 0 5 5 5 1 PH domain DnaJ PF00226.31 EGB08717.1 - 0.0013 18.9 0.1 0.0029 17.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 EGB08717.1 - 0.0042 17.1 10.8 0.9 9.8 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat VIT1 PF01988.19 EGB08718.1 - 2.1e-33 116.0 5.8 2.7e-33 115.7 5.8 1.1 1 0 0 1 1 1 1 VIT family Arginosuc_synth PF00764.19 EGB08719.1 - 1.5e-136 455.7 0.0 1.8e-136 455.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EGB08719.1 - 0.0045 16.5 0.1 0.0082 15.7 0.1 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Cupredoxin_1 PF13473.6 EGB08719.1 - 0.18 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Cupredoxin-like domain UDPGP PF01704.18 EGB08720.1 - 4.5e-120 401.1 0.0 5e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 EGB08721.1 - 3.6e-27 94.7 0.0 6.6e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGB08721.1 - 9.4e-25 87.0 0.0 2.2e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGB08721.1 - 1e-08 35.7 0.1 2.5e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGB08721.1 - 0.00013 22.1 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fringe PF02434.16 EGB08722.1 - 0.03 13.8 0.0 0.17 11.3 0.0 1.9 1 1 0 1 1 1 0 Fringe-like VCBS PF13517.6 EGB08723.1 - 2.8e-105 344.9 268.8 1.4e-08 35.2 10.5 23.4 7 5 17 24 24 24 24 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella REJ PF02010.15 EGB08723.1 - 3.9e-22 78.7 0.0 2.4e-21 76.1 0.0 2.0 1 1 1 2 2 2 1 REJ domain AbfS_sensor PF18225.1 EGB08723.1 - 4.7e-08 32.8 0.0 71 3.4 0.0 11.8 16 0 0 16 16 16 0 Sensor histidine kinase (AbfS) sensor domain Telomere_Sde2_2 PF13297.6 EGB08724.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal SAP PF02037.27 EGB08724.1 - 0.033 14.0 0.3 0.064 13.0 0.0 1.6 2 0 0 2 2 2 0 SAP domain MTBP_N PF14918.6 EGB08724.1 - 0.057 12.9 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding Exostosin PF03016.15 EGB08725.1 - 8.6e-06 25.2 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Exostosin family CRT-like PF08627.10 EGB08726.1 - 1.8e-23 83.0 0.1 2.3e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EGB08726.1 - 0.0064 16.7 6.0 0.0064 16.7 6.0 3.2 3 0 0 3 3 3 1 EamA-like transporter family PTEN_C2 PF10409.9 EGB08728.1 - 1e-12 48.0 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGB08728.1 - 8.5e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGB08728.1 - 0.0091 16.0 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family VEK-30 PF12107.8 EGB08728.1 - 0.03 14.2 0.2 0.095 12.6 0.2 1.9 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway PTPlike_phytase PF14566.6 EGB08728.1 - 0.084 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGB08728.1 - 0.29 10.7 0.0 0.43 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-MYND PF01753.18 EGB08729.1 - 3.5e-05 23.8 11.3 9.2e-05 22.5 11.3 1.8 1 0 0 1 1 1 1 MYND finger COX7B PF05392.11 EGB08729.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB ProRS-C_1 PF09180.11 EGB08729.1 - 0.16 12.2 0.3 0.85 9.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal Pyr_redox_2 PF07992.14 EGB08730.1 - 9.3e-54 182.6 5.3 1.5e-53 181.9 5.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB08730.1 - 1.2e-27 96.4 0.4 2.4e-27 95.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB08730.1 - 3.4e-20 72.4 7.6 8.6e-18 64.7 0.4 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB08730.1 - 6.2e-17 61.8 1.5 8.6e-16 58.1 1.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGB08730.1 - 0.0019 17.6 1.4 0.0019 17.6 1.4 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB08730.1 - 0.0036 16.5 3.9 0.0036 16.5 3.9 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 EGB08730.1 - 0.0076 16.5 0.5 0.0076 16.5 0.5 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB08730.1 - 0.011 15.4 7.7 0.13 11.8 2.3 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 EGB08730.1 - 0.016 14.3 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGB08730.1 - 0.017 13.8 4.2 0.41 9.3 1.4 2.6 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 EGB08730.1 - 0.025 14.6 1.8 8.8 6.3 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 EGB08730.1 - 0.026 13.8 0.3 0.026 13.8 0.3 2.1 3 0 0 3 3 3 0 Thi4 family 2-Hacid_dh_C PF02826.19 EGB08730.1 - 0.58 9.5 2.6 3.6 6.9 0.0 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGB08730.1 - 0.64 10.5 2.4 4.3 7.8 0.1 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding GIDA PF01134.22 EGB08730.1 - 3.5 6.6 8.8 0.62 9.1 2.5 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A SHIPPO-rpt PF07004.12 EGB08731.1 - 9e-11 42.2 51.4 0.051 14.5 1.5 9.5 9 1 0 9 9 9 9 Sperm-tail PG-rich repeat ABC1 PF03109.16 EGB08734.1 - 1.2e-19 70.6 0.0 2.3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DUF908 PF06012.12 EGB08734.1 - 0.24 10.8 0.1 0.41 10.0 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) 2-Hacid_dh_C PF02826.19 EGB08735.1 - 1.1e-20 73.8 0.0 1.4e-19 70.1 0.0 2.3 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGB08735.1 - 2.6e-15 56.3 0.1 4.4e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EGB08735.1 - 5e-05 23.0 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 EGB08735.1 - 0.0002 21.6 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_4 PF13291.6 EGB08735.1 - 0.025 15.2 0.1 0.053 14.1 0.1 1.5 1 0 0 1 1 1 0 ACT domain Oxidored_FMN PF00724.20 EGB08736.1 - 2.7e-27 96.0 0.0 2.4e-26 92.8 0.0 2.0 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family AAA_assoc PF14363.6 EGB08736.1 - 0.065 13.6 0.0 15 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA PDZ_6 PF17820.1 EGB08736.1 - 0.077 12.8 0.2 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Ank_2 PF12796.7 EGB08737.1 - 7.7e-22 77.7 0.1 2.2e-06 28.2 0.0 4.0 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08737.1 - 3.3e-19 69.0 0.2 3.1e-07 30.8 0.0 5.9 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08737.1 - 1.1e-14 53.1 0.1 0.004 17.5 0.0 7.0 6 0 0 6 6 6 3 Ankyrin repeat Bestrophin PF01062.21 EGB08737.1 - 1.2e-12 47.8 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ank PF00023.30 EGB08737.1 - 3.2e-12 46.3 0.0 0.02 15.3 0.0 6.2 5 0 0 5 5 5 2 Ankyrin repeat Choline_kinase PF01633.20 EGB08737.1 - 9.2e-09 35.2 0.0 2.1e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase Ank_5 PF13857.6 EGB08737.1 - 4.1e-08 33.3 3.2 0.14 12.5 0.0 6.0 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Methyltransf_21 PF05050.12 EGB08737.1 - 1.1e-07 32.0 0.0 2.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain PHD PF00628.29 EGB08737.1 - 5e-06 26.3 0.7 5e-06 26.3 0.7 2.5 2 0 0 2 2 2 1 PHD-finger Cupin_2 PF07883.11 EGB08737.1 - 0.0025 17.5 0.1 0.0056 16.4 0.1 1.5 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 EGB08737.1 - 0.013 16.0 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_1 PF00190.22 EGB08737.1 - 0.026 14.1 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Cupin Glyco_transf_20 PF00982.21 EGB08738.1 - 1.6e-109 366.8 0.0 2e-109 366.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGB08738.1 - 2.1e-42 144.8 0.0 7.4e-42 143.1 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_transf_8 PF01501.20 EGB08739.1 - 1.5e-26 93.5 0.0 3.3e-26 92.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 EGB08739.1 - 0.00066 19.2 0.0 0.00085 18.8 0.0 1.1 1 0 0 1 1 1 1 Glucosyltransferase 24 PK PF00224.21 EGB08740.1 - 1.1e-132 442.2 0.1 1.5e-132 441.7 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGB08740.1 - 4.2e-13 49.6 0.2 1.3e-12 48.0 0.2 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGB08740.1 - 0.00018 20.7 0.7 0.00095 18.4 0.2 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family TPR_12 PF13424.6 EGB08741.1 - 3.5e-72 238.7 81.5 4.4e-16 58.9 3.4 11.3 6 2 8 14 14 14 12 Tetratricopeptide repeat TPR_10 PF13374.6 EGB08741.1 - 5.8e-36 121.4 66.8 3.6e-06 26.7 1.7 14.0 14 0 0 14 14 13 10 Tetratricopeptide repeat Acid_PPase PF12689.7 EGB08741.1 - 2e-25 89.6 0.0 3.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Acid Phosphatase TPR_8 PF13181.6 EGB08741.1 - 5.5e-24 82.3 3.7 0.11 12.8 0.0 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGB08741.1 - 1.6e-21 75.1 9.6 0.00067 19.4 0.2 9.7 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGB08741.1 - 1.9e-19 68.2 33.8 1.9e-05 24.4 0.1 11.6 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGB08741.1 - 3.2e-13 48.7 33.2 0.0002 21.2 0.6 11.0 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGB08741.1 - 1e-06 28.7 1.0 4.5 7.9 0.0 7.6 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB08741.1 - 0.00097 19.3 0.3 4.1 7.7 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EGB08741.1 - 0.004 17.6 2.2 0.004 17.6 2.2 15.2 17 0 0 17 17 11 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB08741.1 - 0.0067 16.5 0.5 0.055 13.6 0.1 2.8 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EGB08741.1 - 0.028 15.2 0.8 0.028 15.2 0.8 14.7 14 2 1 15 15 12 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB08741.1 - 0.037 14.7 19.6 0.94 10.3 0.2 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat Vta1_C PF18097.1 EGB08741.1 - 0.066 12.9 0.0 8 6.3 0.0 3.3 2 0 0 2 2 2 0 Vta1 C-terminal domain EF-hand_1 PF00036.32 EGB08742.1 - 0.0039 16.6 0.6 0.0039 16.6 0.6 2.1 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 EGB08742.1 - 0.0066 15.9 1.1 0.0066 15.9 1.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB08742.1 - 0.014 15.3 0.1 0.055 13.4 0.2 1.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EGB08742.1 - 0.03 14.8 0.9 0.32 11.5 0.3 2.4 1 1 0 2 2 2 0 EF-hand domain pair Hydrolase_4 PF12146.8 EGB08743.1 - 7.4e-06 25.4 0.2 1.7e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PDZ_6 PF17820.1 EGB08743.1 - 4e-05 23.4 0.4 0.00018 21.3 0.1 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EGB08743.1 - 0.0024 18.1 0.0 0.0049 17.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGB08743.1 - 0.25 11.7 0.0 0.55 10.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Glyco_transf_8 PF01501.20 EGB08744.1 - 0.0012 18.5 0.3 0.019 14.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 DEAD PF00270.29 EGB08745.1 - 5.7e-22 78.3 0.1 1.1e-21 77.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB08745.1 - 2.7e-06 27.7 0.0 7.6e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB08745.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arm_APC_u3 PF16629.5 EGB08745.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Armadillo-associated region on APC EF-hand_1 PF00036.32 EGB08746.1 - 2.8e-23 79.7 0.5 2.2e-05 23.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB08746.1 - 1.2e-22 80.1 0.0 2.3e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB08746.1 - 3.7e-19 67.0 1.9 3.5e-06 26.5 0.0 4.5 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EGB08746.1 - 2.8e-15 55.9 4.5 4.5e-07 29.6 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB08746.1 - 2.6e-13 48.8 4.5 0.0011 18.4 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EGB08746.1 - 4.7e-07 30.0 0.0 0.00028 21.1 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 EGB08746.1 - 0.017 15.9 0.0 0.042 14.7 0.0 1.6 1 1 1 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 EGB08746.1 - 0.047 13.6 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EGB08747.1 - 0.00058 19.2 0.2 0.02 14.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 EGB08747.1 - 0.0091 15.5 0.0 0.19 11.3 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EGB08747.1 - 0.013 15.3 0.1 0.1 12.5 0.0 2.4 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 EGB08747.1 - 0.06 13.8 0.4 0.36 11.3 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain pair Tubulin PF00091.25 EGB08748.1 - 3.1e-67 226.6 0.0 4.7e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB08748.1 - 3.9e-40 136.9 0.1 6.7e-40 136.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGB08748.1 - 0.00034 20.9 0.0 0.00063 20.0 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGB08748.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGB08748.1 - 0.041 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Tubulin PF00091.25 EGB08749.1 - 1.7e-38 132.8 0.0 1.8e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 EGB08749.1 - 0.00077 19.2 0.0 0.00083 19.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGB08749.1 - 0.0025 17.0 0.0 0.0027 16.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin like TrmK PF04816.12 EGB08749.1 - 0.044 13.3 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Peptidase_C69 PF03577.15 EGB08750.1 - 2.4e-57 194.7 0.0 2.1e-52 178.4 0.0 2.8 1 1 1 2 2 2 2 Peptidase family C69 Acyltransferase PF01553.21 EGB08751.1 - 2e-12 46.9 0.0 3.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase VPS9 PF02204.18 EGB08752.1 - 1.8e-10 41.0 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RNA_pol_L_2 PF13656.6 EGB08753.1 - 1.5e-21 75.9 0.0 1.9e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGB08753.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Band_7 PF01145.25 EGB08754.1 - 1.5e-15 57.7 0.0 2.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family MFS_1 PF07690.16 EGB08756.1 - 2e-25 89.5 11.9 2.6e-25 89.1 11.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EGB08756.1 - 0.0032 15.9 8.6 0.0032 15.9 8.6 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector LtrA PF06772.11 EGB08756.1 - 0.16 11.2 7.4 0.28 10.4 0.6 2.9 2 1 1 3 3 3 0 Bacterial low temperature requirement A protein (LtrA) Metallophos PF00149.28 EGB08757.1 - 2.2e-05 25.1 0.0 3.9e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB08757.1 - 0.00099 19.3 0.0 0.0018 18.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 EGB08758.1 - 0.14 13.0 0.4 0.51 11.3 0.4 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat Myb_DNA-binding PF00249.31 EGB08759.1 - 8e-23 80.4 7.4 7e-13 48.5 1.8 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB08759.1 - 8.1e-21 74.0 6.4 2.7e-13 49.9 3.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF722 PF05263.11 EGB08759.1 - 0.02 15.1 0.1 0.093 13.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF722) SANT_DAMP1_like PF16282.5 EGB08759.1 - 0.034 14.3 1.0 0.08 13.1 0.8 1.9 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EGB08759.1 - 0.078 13.1 1.9 0.097 12.8 0.2 2.0 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FAM193_C PF15914.5 EGB08759.1 - 0.3 10.9 0.2 0.3 10.9 0.2 2.4 3 0 0 3 3 3 0 FAM193 family C-terminal Spt5_N PF11942.8 EGB08759.1 - 0.55 11.3 7.6 0.11 13.4 2.9 2.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal CN_hydrolase PF00795.22 EGB08760.1 - 3.1e-34 118.5 0.0 3.6e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_21 PF05050.12 EGB08761.1 - 1.6e-06 28.2 0.0 6.4e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase FkbM domain LAP2alpha PF11560.8 EGB08761.1 - 0.049 13.1 0.3 0.1 12.0 0.3 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha Met_10 PF02475.16 EGB08761.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein RRM_1 PF00076.22 EGB08763.1 - 1.9e-19 69.2 0.0 2.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB08763.1 - 0.0095 16.0 0.0 0.043 13.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 EGB08763.1 - 0.017 15.3 0.1 0.081 13.1 0.2 1.7 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter ERO1 PF04137.15 EGB08764.1 - 3.8e-106 355.2 0.0 4.7e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Tubulin PF00091.25 EGB08765.1 - 1e-67 228.2 0.0 1.7e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB08765.1 - 2e-40 137.9 0.1 3e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGB08765.1 - 0.00014 22.2 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGB08765.1 - 0.003 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGB08765.1 - 0.02 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Methyltransf_25 PF13649.6 EGB08766.1 - 1.1e-05 26.1 0.1 1.6e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB08766.1 - 0.0002 22.0 0.0 0.00032 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB08766.1 - 0.00029 20.4 0.2 0.00042 19.9 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGB08766.1 - 0.00051 19.5 0.1 0.00065 19.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EGB08766.1 - 0.097 12.3 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 EGB08766.1 - 0.19 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 EGB08767.1 - 4.1e-13 49.0 37.4 4.1e-13 49.0 37.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SPX PF03105.19 EGB08767.1 - 2.9e-10 40.6 0.1 2.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 SPX domain bZIP_1 PF00170.21 EGB08768.1 - 0.00016 21.7 7.3 0.00029 20.9 7.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGB08768.1 - 0.0034 17.4 10.8 0.0034 17.4 10.8 2.5 3 0 0 3 3 3 1 Basic region leucine zipper HTH_32 PF13565.6 EGB08768.1 - 0.021 15.4 2.0 0.021 15.4 2.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Methyltransf_25 PF13649.6 EGB08769.1 - 8.1e-09 36.1 2.1 8.1e-07 29.7 0.1 2.8 3 0 0 3 3 3 1 Methyltransferase domain Acetyltransf_1 PF00583.25 EGB08769.1 - 2e-07 31.2 0.0 3.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Rhodanese PF00581.20 EGB08769.1 - 1.1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_31 PF13847.6 EGB08769.1 - 6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_10 PF13673.7 EGB08769.1 - 0.00017 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_11 PF08241.12 EGB08769.1 - 0.00031 21.3 0.3 0.0016 19.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain FR47 PF08445.10 EGB08769.1 - 0.0019 18.1 0.1 0.0036 17.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGB08769.1 - 0.0084 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ELFV_dehydrog PF00208.21 EGB08771.1 - 1.4e-33 116.6 0.0 1.8e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EGB08771.1 - 8.4e-33 113.0 0.0 1.3e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 EGB08771.1 - 0.025 15.0 0.2 0.062 13.7 0.2 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EGB08771.1 - 0.03 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA PF00004.29 EGB08772.1 - 2.6e-40 137.9 0.0 3.8e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB08772.1 - 4.8e-14 51.9 0.8 4.8e-14 51.9 0.8 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EGB08772.1 - 4.6e-08 33.6 0.3 4.3e-05 24.0 0.0 2.6 2 1 1 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 EGB08772.1 - 1.4e-07 31.6 0.1 1.5e-06 28.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB08772.1 - 7.9e-07 29.4 0.0 0.00018 21.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGB08772.1 - 5.6e-06 26.2 0.0 1.5e-05 24.8 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGB08772.1 - 1.9e-05 24.9 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGB08772.1 - 0.00012 21.5 0.1 0.00035 19.9 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGB08772.1 - 0.00028 20.3 0.2 0.00057 19.3 0.2 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGB08772.1 - 0.00035 20.3 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 EGB08772.1 - 0.0004 20.7 0.0 0.00071 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB08772.1 - 0.0011 19.1 0.0 0.0019 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGB08772.1 - 0.0014 19.1 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB08772.1 - 0.0027 17.5 0.1 0.0081 15.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EGB08772.1 - 0.0027 17.2 0.1 0.009 15.5 0.1 1.7 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 EGB08772.1 - 0.0031 17.1 0.0 0.0074 15.8 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGB08772.1 - 0.0033 18.0 0.0 0.0052 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGB08772.1 - 0.0044 16.7 0.0 0.019 14.6 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 EGB08772.1 - 0.0047 17.0 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGB08772.1 - 0.005 16.6 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EGB08772.1 - 0.021 14.7 0.0 0.066 13.1 0.0 1.7 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 EGB08772.1 - 0.023 14.3 0.5 0.17 11.5 0.2 2.4 1 1 2 3 3 3 0 AAA domain TsaE PF02367.17 EGB08772.1 - 0.031 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 EGB08772.1 - 0.035 13.2 0.0 0.052 12.6 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain Sigma54_activ_2 PF14532.6 EGB08772.1 - 0.038 14.1 0.0 0.082 13.0 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 EGB08772.1 - 0.05 13.4 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 EGB08772.1 - 0.051 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 EGB08772.1 - 0.057 12.5 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EGB08772.1 - 0.086 12.6 0.0 0.093 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EGB08772.1 - 0.086 12.2 0.0 0.8 9.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 EGB08772.1 - 0.14 12.5 0.4 0.32 11.3 0.2 1.7 1 1 1 2 2 1 0 AAA domain Methyltransf_5 PF01795.19 EGB08773.1 - 1.8e-83 280.6 0.0 2.1e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 EGB08773.1 - 0.0022 17.8 0.1 0.0067 16.2 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB08773.1 - 0.044 14.5 0.5 0.11 13.3 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain PepSY_2 PF13670.6 EGB08773.1 - 0.75 9.8 3.4 2 8.5 3.4 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Prefoldin PF02996.17 EGB08775.1 - 1.6e-22 79.7 0.1 2.1e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit CSD PF00313.22 EGB08776.1 - 8e-18 64.1 0.5 7.9e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain U-box PF04564.15 EGB08776.1 - 2.4e-16 59.7 0.0 4.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain tRNA-synt_2c PF01411.19 EGB08778.1 - 1.7e-182 607.8 0.0 2e-181 604.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGB08778.1 - 2.1e-14 53.3 0.0 4.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain C2 PF00168.30 EGB08780.1 - 6.6e-85 280.1 0.1 3.9e-14 52.8 0.0 8.3 8 0 0 8 8 8 8 C2 domain Ferlin_C PF16165.5 EGB08780.1 - 0.008 16.1 2.5 0.029 14.3 0.0 2.8 2 0 0 2 2 2 1 Ferlin C-terminus NT-C2 PF10358.9 EGB08780.1 - 0.062 13.0 0.1 0.22 11.2 0.1 1.9 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins FerI PF08151.12 EGB08780.1 - 0.095 12.8 0.0 0.095 12.8 0.0 3.2 3 1 0 3 3 3 0 FerI (NUC094) domain CS PF04969.16 EGB08781.1 - 0.00062 20.7 0.0 0.0031 18.5 0.0 1.9 1 1 0 1 1 1 1 CS domain PLDc_3 PF13918.6 EGB08781.1 - 0.086 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 PLD-like domain DUF5600 PF18150.1 EGB08782.1 - 6.2e-16 58.9 0.0 1.2e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 EGB08782.1 - 5.7e-10 39.5 0.0 0.00098 19.2 0.0 2.2 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 EGB08782.1 - 4.3e-08 33.2 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGB08782.1 - 0.044 14.0 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGB08782.1 - 0.046 13.3 0.1 7 6.1 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 EGB08782.1 - 0.047 13.9 0.1 0.094 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 EGB08782.1 - 0.094 12.1 0.1 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGB08782.1 - 0.1 12.1 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 EGB08782.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin Hydrolase_4 PF12146.8 EGB08783.1 - 3.8e-10 39.4 0.1 6e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB08783.1 - 3.3e-07 30.2 0.2 0.00016 21.4 0.4 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.10 EGB08783.1 - 0.021 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Thioesterase PF00975.20 EGB08783.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 EGB08783.1 - 0.23 10.7 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Pkinase PF00069.25 EGB08785.1 - 1.8e-27 96.3 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08785.1 - 2.7e-11 43.3 0.0 3.6e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB08785.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Amidohydro_2 PF04909.14 EGB08786.1 - 1.2e-11 45.0 0.5 2e-11 44.3 0.5 1.6 1 1 0 1 1 1 1 Amidohydrolase DUF3086 PF11285.8 EGB08786.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Glyco_hydro_79n PF03662.14 EGB08787.1 - 3.4e-59 200.4 0.0 3.8e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain MFS_1 PF07690.16 EGB08788.1 - 5.8e-08 32.0 65.1 9.3e-08 31.4 25.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily COPI_assoc PF08507.10 EGB08788.1 - 6.8e-08 32.6 5.2 6.8e-08 32.6 5.2 2.6 2 0 0 2 2 2 1 COPI associated protein Nodulin-like PF06813.13 EGB08788.1 - 1.5e-07 31.1 8.6 5.2e-07 29.4 8.6 1.9 1 0 0 1 1 1 1 Nodulin-like DJ-1_PfpI PF01965.24 EGB08789.1 - 1e-13 51.4 0.8 1.6e-12 47.5 0.8 2.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGB08789.1 - 9.8e-06 25.4 0.0 0.00029 20.6 0.0 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like LRR_4 PF12799.7 EGB08790.1 - 2.3e-29 100.9 13.2 1.8e-05 25.0 0.0 7.5 7 0 0 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB08790.1 - 2e-28 97.9 18.8 6e-10 38.7 1.2 6.7 4 3 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 EGB08790.1 - 4.5e-09 35.6 22.4 4.6 8.2 0.0 10.8 11 2 0 11 11 11 3 Leucine Rich Repeat LRR_9 PF14580.6 EGB08790.1 - 5.8e-05 22.7 1.5 0.013 15.0 0.1 3.4 2 1 1 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 EGB08790.1 - 0.0025 17.7 28.5 0.43 10.8 0.1 9.0 10 0 0 10 10 10 3 Leucine Rich repeat CREPT PF16566.5 EGB08790.1 - 0.1 12.8 1.0 26 4.9 0.1 4.2 3 1 2 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour Bromodomain PF00439.25 EGB08791.1 - 1e-14 54.3 0.0 1.8e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Asp_Arg_Hydrox PF05118.15 EGB08792.1 - 1.8e-36 125.4 0.0 3e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase LRR_6 PF13516.6 EGB08792.1 - 1.3e-11 43.6 7.5 0.0075 16.2 0.1 4.5 4 0 0 4 4 4 4 Leucine Rich repeat LRR_4 PF12799.7 EGB08792.1 - 0.0044 17.4 0.6 0.032 14.7 0.0 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) FXR_C1 PF16096.5 EGB08792.1 - 2.8 8.2 6.1 13 6.1 5.1 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 RRM_1 PF00076.22 EGB08794.1 - 8.7e-21 73.5 0.0 5.7e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB08794.1 - 0.0014 18.7 0.0 0.95 9.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif DUF4616 PF15394.6 EGB08794.1 - 0.027 13.5 0.4 0.034 13.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) SlyX PF04102.12 EGB08794.1 - 0.047 14.3 1.5 1.1 10.0 0.3 2.5 2 0 0 2 2 2 0 SlyX CEP63 PF17045.5 EGB08794.1 - 2 8.2 6.4 1.4 8.7 3.0 1.9 1 1 0 2 2 2 0 Centrosomal protein of 63 kDa DUF4407 PF14362.6 EGB08794.1 - 3.8 6.8 10.0 6.6 6.0 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 EGB08794.1 - 3.9 7.6 11.8 29 4.8 11.8 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) C1_1 PF00130.22 EGB08795.1 - 2.4e-07 30.5 10.2 4e-07 29.8 10.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 EGB08795.1 - 0.0011 19.2 0.0 0.052 13.8 0.0 3.0 3 0 0 3 3 3 1 C2 domain PRT_C PF08372.10 EGB08795.1 - 0.0055 16.5 0.3 0.034 13.9 0.1 2.1 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 EGB08795.1 - 0.15 12.1 1.2 0.57 10.1 0.2 2.1 2 0 0 2 2 2 0 Reticulon C1_2 PF03107.16 EGB08795.1 - 1.1 9.6 7.0 2 8.8 7.0 1.5 1 0 0 1 1 1 0 C1 domain VCBS PF13517.6 EGB08796.1 - 1.3e-18 67.3 26.4 5.7e-10 39.6 4.9 3.7 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB08796.1 - 3.1e-12 46.4 21.3 0.00052 20.1 1.8 4.4 3 0 0 3 3 3 3 FG-GAP repeat BBS2_Mid PF14783.6 EGB08796.1 - 0.08 13.0 0.0 36 4.5 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CBFD_NFYB_HMF PF00808.23 EGB08797.1 - 5.6e-23 81.0 0.2 1.5e-22 79.6 0.2 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB08797.1 - 0.018 15.4 0.0 0.028 14.8 0.0 1.3 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Coq4 PF05019.13 EGB08798.1 - 2.2e-79 265.9 0.0 2.5e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 CRAL_TRIO PF00650.20 EGB08799.1 - 7e-11 42.1 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Ion_trans PF00520.31 EGB08799.1 - 9e-06 25.1 9.5 3.1e-05 23.3 9.5 1.8 1 1 0 1 1 1 1 Ion transport protein Ank PF00023.30 EGB08799.1 - 0.004 17.6 2.0 8.6 7.0 0.2 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EGB08799.1 - 0.027 14.8 2.0 14 6.1 0.1 3.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08799.1 - 0.8 10.5 6.5 12 6.8 0.1 4.3 4 0 0 4 4 4 0 Ankyrin repeat Asn_synthase PF00733.21 EGB08800.1 - 9.5e-94 315.0 0.9 9.7e-93 311.6 0.9 2.0 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGB08800.1 - 1.2e-32 112.4 0.0 2.6e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGB08800.1 - 5.7e-22 78.4 0.0 1.2e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGB08800.1 - 1.2e-05 24.9 0.0 3.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 EGB08800.1 - 0.0059 15.7 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 NAD synthase Hydrolase_4 PF12146.8 EGB08801.1 - 7e-30 104.1 0.0 7.8e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB08801.1 - 0.023 14.3 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold GDA1_CD39 PF01150.17 EGB08802.1 - 2.1e-55 188.1 0.0 3.1e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ABC_tran PF00005.27 EGB08803.1 - 1.6e-42 145.3 0.0 2.2e-19 70.3 0.0 4.1 3 1 0 3 3 3 3 ABC transporter AAA_21 PF13304.6 EGB08803.1 - 4.3e-16 59.6 0.1 0.0048 16.8 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB08803.1 - 1.5e-11 44.1 0.1 0.011 15.1 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB08803.1 - 3.3e-08 33.2 0.1 0.0071 16.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB08803.1 - 5.9e-08 33.5 1.7 0.0031 18.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGB08803.1 - 4.8e-07 29.8 0.1 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGB08803.1 - 1.1e-06 28.7 0.0 0.0047 17.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB08803.1 - 3e-06 27.7 0.0 0.057 13.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGB08803.1 - 1.6e-05 25.2 0.0 0.024 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGB08803.1 - 3.7e-05 23.6 0.0 0.29 10.8 0.0 2.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 EGB08803.1 - 6.1e-05 23.3 0.0 0.076 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB08803.1 - 0.00016 21.6 0.5 0.45 10.4 1.1 2.8 2 1 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 EGB08803.1 - 0.00017 21.8 0.0 0.079 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGB08803.1 - 0.00037 20.9 0.0 0.46 10.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB08803.1 - 0.00062 20.1 0.0 1.9 8.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 EGB08803.1 - 0.00095 18.4 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_27 PF13514.6 EGB08803.1 - 0.0017 18.0 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGB08803.1 - 0.0018 18.1 0.0 1.3 8.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 EGB08803.1 - 0.0034 16.4 0.2 0.24 10.4 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGB08803.1 - 0.0036 17.8 0.0 2.2 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EGB08803.1 - 0.0051 17.0 0.0 0.69 10.1 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EGB08803.1 - 0.0058 16.2 0.0 0.34 10.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 EGB08803.1 - 0.0061 16.8 0.1 5.1 7.4 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 EGB08803.1 - 0.0082 15.9 0.0 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 EGB08803.1 - 0.01 15.8 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 EGB08803.1 - 0.013 15.5 0.1 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EGB08803.1 - 0.015 15.1 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGB08803.1 - 0.019 15.0 0.0 4 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGB08803.1 - 0.027 13.7 0.1 2.2 7.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 EGB08803.1 - 0.027 14.4 0.3 7 6.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain G-alpha PF00503.20 EGB08803.1 - 0.028 13.6 0.0 6.5 5.8 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit Adeno_IVa2 PF02456.15 EGB08803.1 - 0.046 12.5 0.2 7.4 5.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein TsaE PF02367.17 EGB08803.1 - 0.056 13.5 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGB08803.1 - 0.067 12.9 0.3 8.1 6.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein MukB PF04310.12 EGB08803.1 - 0.067 13.0 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal Viral_helicase1 PF01443.18 EGB08803.1 - 0.072 12.8 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 EGB08803.1 - 0.083 12.1 0.2 1.9 7.7 0.0 2.6 3 1 0 3 3 3 0 Septin GTP_EFTU PF00009.27 EGB08803.1 - 0.095 12.2 0.0 9.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_13 PF13166.6 EGB08803.1 - 0.095 11.3 0.0 5.2 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGB08803.1 - 0.11 12.1 0.0 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EGB08803.1 - 0.12 11.9 0.1 7.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_ATPase PF09818.9 EGB08803.1 - 0.12 11.1 0.8 6.1 5.5 0.1 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ATP_bind_1 PF03029.17 EGB08803.1 - 0.19 11.5 0.8 5.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EGB08803.1 - 0.49 10.0 1.8 6.8 6.2 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain 4HBT PF03061.22 EGB08804.1 - 6.8e-10 39.2 1.2 2.1e-06 28.0 0.3 2.4 2 0 0 2 2 2 2 Thioesterase superfamily TauD PF02668.16 EGB08805.1 - 2.8e-27 96.2 0.0 5.4e-27 95.2 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.25 EGB08806.1 - 8.8e-49 166.2 0.0 1e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08806.1 - 1.8e-18 66.8 0.0 3.1e-18 66.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB08806.1 - 5.2e-06 26.0 0.0 0.00027 20.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGB08806.1 - 0.0073 16.3 3.8 0.044 13.7 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGB08806.1 - 0.048 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TPR_2 PF07719.17 EGB08806.1 - 0.071 13.2 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ABA_WDS PF02496.16 EGB08806.1 - 0.23 12.0 1.4 0.28 11.7 0.1 1.8 2 0 0 2 2 2 0 ABA/WDS induced protein PKD_channel PF08016.12 EGB08807.1 - 5.1e-48 163.8 0.0 7.2e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EGB08807.1 - 5.5e-14 52.0 7.0 1.1e-13 51.1 7.0 1.4 1 0 0 1 1 1 1 Ion transport protein CCT PF06203.14 EGB08807.1 - 6.7e-12 45.3 12.9 6.7e-12 45.3 12.9 1.7 2 0 0 2 2 2 1 CCT motif TAF4 PF05236.14 EGB08807.1 - 0.021 14.6 0.2 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SieB PF14163.6 EGB08807.1 - 0.19 11.2 0.0 0.65 9.5 0.0 1.8 2 0 0 2 2 2 0 Super-infection exclusion protein B Pkinase PF00069.25 EGB08808.1 - 2.2e-57 194.4 0.0 2.6e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08808.1 - 2.1e-20 73.1 0.0 2.7e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB08808.1 - 1.5e-08 34.9 0.2 0.00046 20.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGB08808.1 - 2.1e-06 27.3 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB08808.1 - 1.9e-05 24.1 0.0 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.20 EGB08808.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PPDK_N PF01326.19 EGB08810.1 - 7.3e-67 226.0 0.0 1.2e-66 225.2 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 EGB08810.1 - 3.9e-09 36.1 0.0 1.1e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain NAD_binding_6 PF08030.12 EGB08810.1 - 7.1e-05 23.0 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGB08810.1 - 0.00031 20.9 6.5 0.00031 20.9 6.5 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component LRR_8 PF13855.6 EGB08810.1 - 0.0024 17.6 0.1 0.0048 16.6 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EGB08810.1 - 0.19 12.2 0.1 0.96 10.0 0.0 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Tic110 PF16940.5 EGB08811.1 - 3.7e-24 85.1 12.2 4.8e-11 41.9 0.8 4.9 4 1 1 5 5 5 3 Chloroplast envelope transporter Methyltransf_24 PF13578.6 EGB08811.1 - 1.3e-15 58.3 0.7 1e-12 49.0 0.3 4.2 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 EGB08811.1 - 0.00057 19.4 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGB08811.1 - 0.027 15.2 0.0 0.35 11.6 0.0 3.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGB08811.1 - 0.036 13.9 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 EGB08811.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Lipase_GDSL_2 PF13472.6 EGB08812.1 - 1.4e-08 35.3 0.0 3.8e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Mito_carr PF00153.27 EGB08813.1 - 5e-14 52.0 0.1 1.1e-12 47.7 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein FKBP_C PF00254.28 EGB08814.1 - 2.3e-32 111.1 0.0 2.7e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Amidohydro_2 PF04909.14 EGB08815.1 - 7.1e-24 85.1 3.9 1.7e-23 83.8 3.9 1.7 1 1 0 1 1 1 1 Amidohydrolase Ribosomal_L37ae PF01780.19 EGB08816.1 - 7.1e-39 131.8 8.4 8e-39 131.6 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EGB08816.1 - 0.0074 16.2 3.0 0.011 15.6 3.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Ima1_N PF09779.9 EGB08816.1 - 0.012 16.4 0.1 0.015 16.2 0.1 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain Elf1 PF05129.13 EGB08816.1 - 0.02 14.9 2.8 0.025 14.6 2.8 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like C1_2 PF03107.16 EGB08816.1 - 0.21 11.9 3.1 1.4 9.3 3.1 2.0 1 1 0 1 1 1 0 C1 domain DUF2175 PF09943.9 EGB08816.1 - 0.71 10.2 3.9 16 5.8 0.3 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-BED PF02892.15 EGB08816.1 - 0.81 9.8 10.0 0.62 10.1 0.6 2.5 2 1 1 3 3 3 0 BED zinc finger zf-ribbon_3 PF13248.6 EGB08816.1 - 1 8.9 5.0 0.77 9.2 1.6 2.3 2 1 1 3 3 3 0 zinc-ribbon domain Tyrosinase PF00264.20 EGB08817.1 - 3.1e-09 37.4 5.0 7.4e-05 23.1 3.0 2.2 2 0 0 2 2 2 2 Common central domain of tyrosinase Sugarporin_N PF11471.8 EGB08818.1 - 0.00031 20.6 3.4 0.43 10.6 0.4 3.0 2 0 0 2 2 2 2 Maltoporin periplasmic N-terminal extension EF-hand_6 PF13405.6 EGB08819.1 - 3.5e-12 45.2 9.1 0.052 13.5 0.5 6.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 EGB08819.1 - 9e-11 40.5 11.3 0.0099 15.4 0.0 6.2 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 EGB08819.1 - 3e-10 40.4 4.0 0.00024 21.5 0.4 3.6 3 1 0 3 3 3 2 EF-hand domain pair Suf PF05843.14 EGB08819.1 - 1.8e-09 38.0 0.0 5.6e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) EF-hand_8 PF13833.6 EGB08819.1 - 7.3e-08 32.1 2.9 0.00021 21.1 0.4 2.8 2 0 0 2 2 2 2 EF-hand domain pair VCBS PF13517.6 EGB08819.1 - 7.5e-08 32.9 5.9 3.7e-07 30.6 5.9 2.4 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.6 EGB08819.1 - 0.12 11.9 0.0 0.12 11.9 0.0 5.6 6 0 0 6 6 6 0 EF hand TPR_19 PF14559.6 EGB08819.1 - 4.3 7.9 18.3 0.81 10.2 6.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PX PF00787.24 EGB08820.1 - 0.024 14.6 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 PX domain WD40 PF00400.32 EGB08821.1 - 3.6e-16 59.3 15.3 0.011 16.6 0.0 10.0 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08821.1 - 3e-09 37.1 0.0 0.0036 17.6 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGB08821.1 - 6.2 7.5 14.0 6.2 7.4 0.1 6.0 5 1 0 5 5 5 0 PQQ-like domain LRR_6 PF13516.6 EGB08822.1 - 6.8e-14 50.7 16.4 1.2 9.3 0.0 12.5 14 0 0 14 14 14 5 Leucine Rich repeat LRR_4 PF12799.7 EGB08822.1 - 6.6e-13 48.6 0.0 9.5 6.8 0.0 8.9 7 1 2 10 10 10 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB08822.1 - 7.2e-08 32.0 2.0 3.2e+02 2.6 0.0 11.5 13 2 0 13 13 13 0 Leucine Rich Repeat LRR_8 PF13855.6 EGB08822.1 - 0.00011 21.9 0.3 4 7.3 0.0 6.9 8 1 0 8 8 8 1 Leucine rich repeat DUF4675 PF15720.5 EGB08822.1 - 0.085 12.6 2.4 0.33 10.7 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4675) HSF_DNA-bind PF00447.17 EGB08823.1 - 2.1e-12 47.5 0.0 3.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding zf-HC2 PF13490.6 EGB08823.1 - 7.2 6.9 8.3 1 9.6 2.2 2.9 2 0 0 2 2 2 0 Putative zinc-finger Met_10 PF02475.16 EGB08824.1 - 6.5e-49 166.4 0.0 8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EGB08824.1 - 0.00095 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB08824.1 - 0.038 14.7 0.0 0.091 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Resistin PF06954.11 EGB08824.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Resistin Methyltransf_18 PF12847.7 EGB08824.1 - 0.18 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PHO4 PF01384.20 EGB08825.1 - 3.6e-107 358.3 20.1 4.3e-107 358.1 20.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family Myosin_head PF00063.21 EGB08826.1 - 1.5e-188 628.3 0.0 1.9e-188 627.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) POR PF01558.18 EGB08826.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase AAA_22 PF13401.6 EGB08826.1 - 0.078 13.2 0.1 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DSBA PF01323.20 EGB08826.1 - 0.13 12.0 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain ABC_tran PF00005.27 EGB08826.1 - 0.14 12.7 0.3 0.29 11.7 0.3 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EGB08826.1 - 0.15 12.5 0.0 0.5 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Acyl_transf_3 PF01757.22 EGB08827.1 - 9.8e-12 44.6 1.3 1.2e-11 44.3 1.3 1.0 1 0 0 1 1 1 1 Acyltransferase family Virul_fac_BrkB PF03631.15 EGB08827.1 - 0.029 14.0 2.4 0.041 13.5 2.4 1.2 1 0 0 1 1 1 0 Virulence factor BrkB NAD_binding_8 PF13450.6 EGB08828.1 - 2.6e-13 50.0 1.0 9e-13 48.3 1.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGB08828.1 - 9.5e-11 41.6 1.0 2.7e-07 30.2 0.4 2.9 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EGB08828.1 - 1.4e-07 31.0 2.6 0.00033 19.9 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain GMC_oxred_N PF00732.19 EGB08828.1 - 3.5e-07 29.9 0.9 1.2e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 EGB08828.1 - 3.2e-06 27.0 2.9 0.0016 18.1 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGB08828.1 - 0.0003 20.1 0.1 0.0014 17.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGB08828.1 - 0.00048 19.4 0.6 0.0011 18.3 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EGB08828.1 - 0.0039 16.5 0.2 0.0059 15.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain bPH_6 PF10756.9 EGB08828.1 - 0.017 15.2 0.3 0.085 13.0 0.3 2.2 1 0 0 1 1 1 0 Bacterial PH domain Pyr_redox PF00070.27 EGB08828.1 - 0.031 14.8 0.7 0.6 10.7 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB08828.1 - 0.034 12.9 0.2 0.7 8.5 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 EGB08828.1 - 0.49 9.4 2.9 8 5.4 0.1 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Ala_racemase_N PF01168.20 EGB08829.1 - 2.7e-23 82.8 0.1 3.1e-23 82.6 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Oxidored_FMN PF00724.20 EGB08830.1 - 7e-72 242.5 0.0 9.2e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 EGB08830.1 - 1.4e-22 80.3 0.2 3.7e-22 78.9 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB08830.1 - 5.5e-14 52.5 1.6 8.2e-06 26.3 0.4 4.3 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB08830.1 - 1.6e-10 41.0 0.1 7e-10 39.0 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB08830.1 - 4.2e-07 29.9 16.7 7.1e-05 22.5 1.2 4.0 2 1 0 4 4 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EGB08830.1 - 5e-07 28.8 2.3 1.2e-06 27.5 0.2 2.3 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 EGB08830.1 - 5.1e-06 26.0 0.1 5.1e-06 26.0 0.1 2.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EGB08830.1 - 0.00012 21.3 1.6 0.00012 21.3 1.6 2.0 1 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EGB08830.1 - 0.00024 20.4 1.5 0.0017 17.7 0.3 2.5 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EGB08830.1 - 0.00026 20.3 0.1 0.00073 18.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EGB08830.1 - 0.00027 20.4 0.1 0.0004 19.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGB08830.1 - 0.00065 19.0 0.3 0.056 12.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB08830.1 - 0.00086 18.5 0.1 0.05 12.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EGB08830.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGB08830.1 - 0.0067 15.5 0.2 0.012 14.6 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 EGB08830.1 - 0.02 14.8 0.7 0.075 12.9 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGB08830.1 - 0.027 13.8 0.0 0.076 12.3 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EGB08830.1 - 0.031 14.3 5.6 0.22 11.5 0.1 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding FMO-like PF00743.19 EGB08830.1 - 0.034 12.6 0.1 0.094 11.1 0.0 1.7 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 EGB08830.1 - 0.094 12.7 0.1 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EGB08830.1 - 0.24 11.0 0.3 0.46 10.0 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Kinesin PF00225.23 EGB08831.1 - 5.6e-40 137.3 0.1 2.3e-22 79.4 0.0 2.4 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGB08831.1 - 4.2e-13 49.5 0.0 6.2e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Cyclin_N PF00134.23 EGB08832.1 - 2e-25 89.0 0.2 1.1e-24 86.6 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Glycos_transf_2 PF00535.26 EGB08832.1 - 2.4e-18 66.5 0.0 4.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 EGB08832.1 - 4.8e-08 32.6 0.9 1.2e-07 31.2 0.9 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Cyclin_C PF02984.19 EGB08832.1 - 0.0019 18.3 0.4 0.03 14.4 0.2 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Glyco_tranf_2_2 PF10111.9 EGB08832.1 - 0.025 14.1 0.0 0.082 12.4 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Kinesin PF00225.23 EGB08833.1 - 2.7e-61 207.3 0.5 4.8e-61 206.5 0.5 1.4 1 0 0 1 1 1 1 Kinesin motor domain K_channel_TID PF07941.11 EGB08833.1 - 0.16 12.4 1.8 0.7 10.4 1.8 2.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Amino_oxidase PF01593.24 EGB08834.1 - 6.4e-16 58.7 0.0 8.6e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB08834.1 - 8.1e-08 32.4 0.0 2.4e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGB08834.1 - 2.7e-07 30.1 2.2 3.5e-05 23.2 0.9 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB08834.1 - 2.7e-05 23.5 3.8 0.0068 15.5 2.8 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGB08834.1 - 4.8e-05 23.1 0.4 0.0014 18.3 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB08834.1 - 0.0011 19.5 0.5 0.0069 16.9 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB08834.1 - 0.0019 17.5 1.8 0.0044 16.3 1.2 1.7 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EGB08834.1 - 0.004 16.7 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EGB08834.1 - 0.0043 17.0 1.4 0.0072 16.2 1.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EGB08834.1 - 0.0079 14.9 2.8 0.034 12.9 1.3 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EGB08834.1 - 0.0081 15.5 0.5 0.016 14.6 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGB08834.1 - 0.016 14.3 2.7 0.056 12.5 2.3 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EGB08834.1 - 0.027 14.4 1.4 1.6 8.7 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGB08834.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGB08834.1 - 0.11 11.8 0.2 0.19 11.0 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Filament PF00038.21 EGB08835.1 - 0.0096 15.5 2.6 0.0096 15.5 2.6 2.5 3 1 0 3 3 3 1 Intermediate filament protein SnoaL PF07366.12 EGB08835.1 - 0.021 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase bZIP_1 PF00170.21 EGB08835.1 - 0.078 13.1 0.5 0.078 13.1 0.5 3.3 5 1 0 5 5 4 0 bZIP transcription factor KASH_CCD PF14662.6 EGB08835.1 - 0.11 12.3 1.3 0.54 10.1 0.3 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Atg14 PF10186.9 EGB08835.1 - 0.32 10.0 4.4 0.29 10.2 1.7 2.2 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uso1_p115_C PF04871.13 EGB08835.1 - 1.1 9.6 10.9 0.084 13.3 2.2 2.8 2 2 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 EGB08835.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.2 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 EGB08835.1 - 1.4 8.9 9.5 0.2 11.7 2.8 2.3 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 EGB08835.1 - 1.4 9.2 14.8 0.32 11.2 0.7 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper Fez1 PF06818.15 EGB08835.1 - 2 8.9 9.0 3.3 8.1 6.9 2.3 2 1 0 2 2 2 0 Fez1 DUF4407 PF14362.6 EGB08835.1 - 2.4 7.4 10.1 14 4.9 10.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EGB08835.1 - 3 8.5 4.9 7.4 7.3 0.1 3.2 3 1 1 4 4 4 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 EGB08835.1 - 3.6 7.7 12.5 4.4 7.4 0.8 4.2 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Chloroa_b-bind PF00504.21 EGB08836.1 - 2.4e-07 31.4 0.2 8.4e-07 29.6 0.2 1.7 1 1 0 1 1 1 1 Chlorophyll A-B binding protein zf-CCHC PF00098.23 EGB08837.1 - 5.8e-08 32.5 2.0 1.2e-07 31.5 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle CN_hydrolase PF00795.22 EGB08837.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase zf-CCHC_3 PF13917.6 EGB08837.1 - 0.18 11.8 2.5 0.42 10.6 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C1 PF00112.23 EGB08838.1 - 7.1e-41 140.7 7.4 9e-41 140.3 7.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease DUF4596 PF15363.6 EGB08838.1 - 0.072 13.3 0.3 0.15 12.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Peptidase_C1_2 PF03051.15 EGB08838.1 - 0.072 11.9 1.2 0.12 11.1 1.2 1.3 1 0 0 1 1 1 0 Peptidase C1-like family Pentapeptide PF00805.22 EGB08840.1 - 8.2e-20 70.1 14.6 7.4e-12 44.7 1.5 3.4 1 1 2 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EGB08840.1 - 1.2e-14 54.2 0.1 1.3e-08 34.8 0.3 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGB08840.1 - 3.7e-08 33.4 12.9 0.00016 21.8 0.5 3.5 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) DUF1997 PF09366.10 EGB08842.1 - 0.00032 20.9 0.0 0.00043 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) DUF2384 PF09722.10 EGB08842.1 - 0.03 14.4 0.6 0.069 13.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) Methyltransf_24 PF13578.6 EGB08843.1 - 0.013 16.5 4.0 0.055 14.5 0.6 3.4 2 0 0 2 2 2 0 Methyltransferase domain Pentapeptide_3 PF13576.6 EGB08843.1 - 0.27 11.4 2.0 3 8.1 0.1 3.0 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGB08844.1 - 0.14 12.4 3.5 0.69 10.1 0.1 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Pkinase PF00069.25 EGB08845.1 - 8.8e-52 176.1 0.0 9.9e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08845.1 - 5.7e-18 65.1 0.0 7.1e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB08845.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB08845.1 - 0.00065 19.1 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Tubulin_C PF03953.17 EGB08846.1 - 1.4e-08 35.0 0.1 2.1e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Het-C PF07217.11 EGB08846.1 - 0.04 12.5 0.0 0.043 12.4 0.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C GCD14 PF08704.10 EGB08847.1 - 6.5e-69 232.3 0.0 1.5e-67 227.9 0.0 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EGB08847.1 - 2.3e-08 34.1 0.0 3.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EGB08847.1 - 0.00021 21.9 0.0 0.00064 20.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB08847.1 - 0.0032 18.1 0.7 0.0058 17.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB08847.1 - 0.005 16.7 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EGB08847.1 - 0.0069 16.0 0.0 0.019 14.6 0.0 1.6 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 EGB08847.1 - 0.025 14.4 0.0 0.051 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain GH3 PF03321.13 EGB08848.1 - 6.8e-05 21.9 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter EF-hand_7 PF13499.6 EGB08848.1 - 0.00029 21.2 0.9 0.0043 17.5 0.1 3.2 2 1 0 2 2 2 1 EF-hand domain pair zf-C2H2_4 PF13894.6 EGB08848.1 - 0.0014 19.3 11.2 0.063 14.2 0.3 4.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGB08848.1 - 0.12 12.2 1.0 30 4.5 0.1 3.5 2 0 0 2 2 2 0 zinc-finger C2H2-type EF-hand_6 PF13405.6 EGB08848.1 - 0.18 11.8 0.0 9.9 6.4 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain FOXP-CC PF16159.5 EGB08848.1 - 0.25 12.0 6.2 0.13 12.9 0.6 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 EGB08848.1 - 2.1 9.0 16.3 0.83 10.2 0.2 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type UDPGP PF01704.18 EGB08849.1 - 1.9e-38 132.2 0.0 2.6e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Methyltransf_11 PF08241.12 EGB08850.1 - 2.6e-20 72.9 0.2 3.4e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB08850.1 - 2.5e-18 66.6 0.3 3.3e-18 66.2 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB08850.1 - 3.2e-09 37.4 0.1 5.2e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB08850.1 - 3.9e-09 36.6 0.0 4.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB08850.1 - 3.6e-06 26.8 0.0 4.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGB08850.1 - 0.00044 20.2 0.8 0.0011 18.9 0.8 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EGB08850.1 - 0.0013 18.1 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGB08850.1 - 0.0013 18.3 0.2 0.002 17.7 0.2 1.3 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EGB08850.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.11 EGB08850.1 - 0.025 14.2 0.1 0.032 13.9 0.1 1.4 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 EGB08850.1 - 0.093 12.7 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain CBS PF00571.28 EGB08851.1 - 6.1e-23 81.0 2.6 1.8e-11 44.3 0.5 2.6 2 0 0 2 2 2 2 CBS domain DSPc PF00782.20 EGB08851.1 - 1.8e-20 73.1 0.0 2.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DHHA1 PF02272.19 EGB08851.1 - 3.9e-09 37.1 0.0 9.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 EGB08851.1 - 1.7e-07 31.4 0.0 3.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 DHH family Tyrosinase PF00264.20 EGB08851.1 - 2e-05 25.0 1.8 4.8e-05 23.7 0.5 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Y_phosphatase PF00102.27 EGB08851.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ion_trans_2 PF07885.16 EGB08852.1 - 9.7e-27 92.8 21.4 2e-14 53.3 6.0 2.1 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 EGB08852.1 - 0.0011 18.3 8.6 0.009 15.3 2.6 2.2 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 EGB08852.1 - 0.0019 18.0 1.3 0.95 9.3 0.0 2.1 2 0 0 2 2 2 2 Ligand-gated ion channel Pkinase PF00069.25 EGB08853.1 - 8.1e-63 212.2 0.0 9.2e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08853.1 - 3.4e-41 141.3 0.0 4.1e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB08853.1 - 1.1e-07 31.5 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB08853.1 - 0.004 16.0 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DnaJ PF00226.31 EGB08854.1 - 2e-19 69.5 0.4 5.3e-19 68.1 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EGB08854.1 - 8.5e-08 31.7 5.8 0.52 10.2 0.0 5.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB08854.1 - 0.00076 19.5 4.7 4.7 7.7 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB08854.1 - 0.019 15.6 12.0 0.019 15.6 12.0 8.2 6 2 0 7 7 7 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGB08854.1 - 0.26 11.4 4.4 6.3 6.9 0.1 3.9 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 EGB08854.1 - 0.64 10.5 6.9 21 5.8 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB08854.1 - 0.98 9.7 40.4 2.3 8.5 0.1 9.2 10 0 0 10 10 10 0 Tetratricopeptide repeat Ribosomal_L35Ae PF01247.18 EGB08855.1 - 3.8e-44 148.8 0.8 4.3e-44 148.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EGB08855.1 - 0.014 15.6 0.1 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 RimM N-terminal domain LRR_6 PF13516.6 EGB08856.1 - 1.4e-06 27.9 0.3 0.00041 20.2 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat DUF521 PF04412.13 EGB08857.1 - 5.7e-118 394.1 0.0 8.4e-118 393.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 EGB08857.1 - 4.2e-30 103.3 0.0 1.4e-29 101.7 0.0 1.9 1 0 0 1 1 1 1 Aconitase X swivel domain ketoacyl-synt PF00109.26 EGB08858.1 - 5.9e-36 124.3 4.2 8.9e-36 123.8 4.2 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB08858.1 - 1.6e-10 41.1 0.0 3.6e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EGB08858.1 - 0.014 15.2 1.4 2.6 8.0 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGB08859.1 - 4.9e-34 118.1 4.9 5.8e-34 117.8 4.9 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB08859.1 - 9.1e-10 38.6 0.1 1.7e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGB08860.1 - 2.9e-42 145.0 1.1 2.9e-42 145.0 1.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB08860.1 - 8.1e-08 32.3 0.3 7.5e-07 29.2 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain RCC1 PF00415.18 EGB08862.1 - 2.3e-48 162.6 14.5 6.3e-12 45.9 0.1 8.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB08862.1 - 3.8e-31 106.2 39.6 2.6e-09 36.6 0.2 7.7 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Osteopontin PF00865.18 EGB08862.1 - 0.097 12.2 10.5 0.13 11.7 10.5 1.1 1 0 0 1 1 1 0 Osteopontin 3-HAO PF06052.12 EGB08863.1 - 3.9e-35 120.7 0.0 5e-32 110.6 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EGB08863.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Cupin domain EF-hand_1 PF00036.32 EGB08864.1 - 1.6e-14 52.3 3.2 7.5e-09 34.5 1.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB08864.1 - 3.5e-14 53.0 0.9 3.7e-14 52.9 0.9 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB08864.1 - 4e-13 49.0 3.6 2.3e-11 43.3 0.7 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB08864.1 - 8e-12 44.1 0.4 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB08864.1 - 2.8e-08 32.9 1.1 4.9e-05 22.6 0.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EGB08864.1 - 0.0011 18.8 0.2 0.0013 18.7 0.2 1.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SUB1_ProdP9 PF18213.1 EGB08864.1 - 0.0025 17.6 0.0 0.0028 17.4 0.0 1.1 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 MotA_activ PF09114.10 EGB08864.1 - 0.003 17.6 0.0 0.0031 17.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor MotA, activation domain EF-hand_9 PF14658.6 EGB08864.1 - 0.024 15.0 0.0 0.027 14.8 0.0 1.0 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB08864.1 - 0.034 14.4 0.1 0.037 14.3 0.1 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 EGB08864.1 - 0.044 13.9 0.0 0.053 13.6 0.0 1.2 1 1 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EGB08864.1 - 0.081 13.8 0.1 0.086 13.7 0.1 1.0 1 0 0 1 1 1 0 EF-hand domain NTS PF15447.6 EGB08864.1 - 0.21 12.1 0.1 0.31 11.6 0.1 1.3 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 EF-hand_1 PF00036.32 EGB08865.1 - 1.3e-26 90.1 10.4 1.6e-06 27.2 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB08865.1 - 1.3e-26 92.8 12.2 1.7e-13 50.8 0.3 3.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGB08865.1 - 1.2e-24 84.1 5.1 4.5e-06 26.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB08865.1 - 6.5e-18 63.4 6.8 0.00011 21.5 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB08865.1 - 3e-15 55.8 10.4 5.1e-08 32.6 0.3 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EGB08865.1 - 7.2e-08 32.6 0.1 0.017 15.5 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 EGB08865.1 - 2.3e-07 30.7 0.9 0.037 14.0 0.1 3.2 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB08865.1 - 0.00023 21.5 0.1 0.6 10.5 0.0 2.4 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGB08865.1 - 0.65 9.9 3.2 9.4 6.2 0.1 3.3 4 0 0 4 4 4 0 EF hand ABM PF03992.16 EGB08866.1 - 5.1e-09 36.1 0.0 6.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase WD40 PF00400.32 EGB08867.1 - 2.5e-13 50.3 24.1 0.00016 22.4 0.9 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB08867.1 - 5.4e-07 29.8 0.0 3 8.2 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EGB08867.1 - 0.00019 21.2 2.8 0.28 11.1 0.1 2.4 2 0 0 2 2 2 2 HIRA B motif Ge1_WD40 PF16529.5 EGB08867.1 - 0.00083 18.4 0.4 2.5 7.0 0.0 3.7 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB08867.1 - 0.022 14.7 0.0 0.076 12.9 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Acetyltransf_7 PF13508.7 EGB08867.1 - 0.16 12.5 0.0 0.69 10.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGB08867.1 - 0.22 11.5 0.1 0.67 9.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-MYND PF01753.18 EGB08868.1 - 2e-09 37.3 17.9 3.9e-09 36.4 17.9 1.5 1 0 0 1 1 1 1 MYND finger CAP59_mtransfer PF11735.8 EGB08868.1 - 2.5e-09 37.2 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_4 PF13704.6 EGB08868.1 - 0.0041 17.6 0.1 0.0086 16.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EGB08868.1 - 0.0072 16.1 0.7 0.015 15.1 0.7 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 zf-C6H2 PF15801.5 EGB08868.1 - 0.89 9.9 10.6 2.3 8.6 10.6 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Voltage_CLC PF00654.20 EGB08869.1 - 1.4e-66 225.2 27.5 1.4e-66 225.2 27.5 3.8 3 2 1 4 4 4 1 Voltage gated chloride channel CBS PF00571.28 EGB08869.1 - 0.02 15.3 0.1 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 CBS domain Sulfotransfer_2 PF03567.14 EGB08869.1 - 0.089 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family DEAD PF00270.29 EGB08870.1 - 2.9e-40 137.9 0.0 4.8e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB08870.1 - 1.6e-19 70.3 0.0 3.5e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGB08870.1 - 1.2e-16 60.6 0.0 2.7e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGB08870.1 - 0.00083 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGB08870.1 - 0.0012 19.1 0.0 0.0038 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma70_r4_2 PF08281.12 EGB08870.1 - 0.021 14.5 1.6 0.05 13.3 1.6 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 SHOCT PF09851.9 EGB08870.1 - 0.2 11.5 7.9 0.067 13.0 2.9 2.8 2 0 0 2 2 2 0 Short C-terminal domain Sulfatase PF00884.23 EGB08871.1 - 6.5e-35 121.0 0.1 1.1e-34 120.2 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 EGB08871.1 - 0.0099 16.6 0.1 0.018 15.8 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase PFU PF09070.11 EGB08871.1 - 0.074 13.3 0.2 0.27 11.5 0.2 1.8 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) DUF4976 PF16347.5 EGB08871.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) JAB PF01398.21 EGB08872.1 - 1.4e-12 47.6 0.1 7.3e-12 45.3 0.1 2.0 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2722 PF10846.8 EGB08874.1 - 0.011 14.8 2.8 0.011 14.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 EGB08874.1 - 0.095 12.7 10.4 0.1 12.6 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 EGB08874.1 - 0.11 11.8 21.1 0.15 11.3 21.1 1.2 1 0 0 1 1 1 0 NOA36 protein Trypan_PARP PF05887.11 EGB08874.1 - 0.15 12.1 7.9 0.26 11.3 7.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PPP4R2 PF09184.11 EGB08874.1 - 0.57 9.7 17.3 0.77 9.3 17.3 1.1 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 EGB08874.1 - 8.4 6.0 29.9 7.2 6.3 28.8 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EGB08874.1 - 9.4 4.3 22.0 12 4.0 22.0 1.1 1 0 0 1 1 1 0 Nop14-like family Adaptin_N PF01602.20 EGB08875.1 - 1.1e-107 360.8 2.6 2.1e-106 356.6 2.6 2.1 1 1 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGB08875.1 - 3.9e-44 150.4 0.0 8.4e-44 149.3 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGB08875.1 - 4.1e-25 88.2 0.0 9.3e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGB08875.1 - 9.5e-13 48.4 7.3 6.3e-07 29.7 0.4 5.5 5 1 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 EGB08875.1 - 9.4e-09 35.5 7.8 0.0084 16.2 0.1 4.4 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGB08875.1 - 9.9e-06 25.4 9.1 0.76 10.2 0.1 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EGB08875.1 - 0.00018 22.0 9.0 0.17 12.4 3.1 4.1 3 1 1 4 4 4 2 HEAT-like repeat HEAT_PBS PF03130.16 EGB08875.1 - 7.8 7.5 8.0 1.8e+02 3.3 0.0 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DEAD PF00270.29 EGB08876.1 - 1.9e-45 154.8 0.1 3e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB08876.1 - 1.4e-30 105.9 0.1 1.2e-29 102.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB08876.1 - 5.6e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGB08876.1 - 0.002 17.9 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB08876.1 - 0.0043 17.4 0.2 0.015 15.7 0.2 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGB08876.1 - 0.0061 16.8 0.1 0.021 15.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EGB08876.1 - 0.023 14.1 0.0 0.068 12.5 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit TniB PF05621.11 EGB08876.1 - 0.069 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 EGB08876.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase PKcGMP_CC PF16808.5 EGB08877.1 - 4.2 7.3 10.1 11 5.9 0.1 4.8 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pyrophosphatase PF00719.19 EGB08878.1 - 2.3e-33 115.3 0.0 3e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Helicase_C PF00271.31 EGB08879.1 - 5.4e-32 110.4 0.2 5.1e-31 107.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB08879.1 - 1.1e-28 100.2 0.0 2.2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase tRNA-synt_1b PF00579.25 EGB08879.1 - 0.065 12.5 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Fanconi_A PF03511.14 EGB08879.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein MCM PF00493.23 EGB08880.1 - 7.7e-101 335.9 0.0 1.1e-100 335.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGB08880.1 - 3.3e-30 104.5 0.5 6.5e-30 103.6 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGB08880.1 - 3.4e-20 72.3 0.5 1e-19 70.7 0.2 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGB08880.1 - 5.5e-07 29.2 0.1 4.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB08880.1 - 7.4e-06 26.0 0.0 4e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGB08880.1 - 0.00029 20.7 0.0 0.00083 19.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EGB08880.1 - 0.022 15.4 0.3 0.093 13.4 0.1 2.3 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 EGB08880.1 - 0.023 14.5 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain AAA PF00004.29 EGB08880.1 - 0.1 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGB08880.1 - 0.11 12.1 0.0 0.91 9.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 EGB08880.1 - 0.14 12.6 1.4 2 8.8 0.1 2.8 2 1 1 3 3 3 0 AAA ATPase domain Phage_integrase PF00589.22 EGB08881.1 - 0.026 14.3 0.0 0.17 11.7 0.0 2.0 1 1 0 1 1 1 0 Phage integrase family Ribosomal_L26 PF16906.5 EGB08881.1 - 0.045 14.2 0.0 0.089 13.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal TLD PF07534.16 EGB08882.1 - 1.3e-11 44.9 0.0 2.6e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 TLD Sel1 PF08238.12 EGB08884.1 - 3.2e-06 27.6 0.2 3.1e-05 24.5 0.2 2.5 2 0 0 2 2 2 1 Sel1 repeat DHHC PF01529.20 EGB08885.1 - 2.5e-25 89.1 7.9 2.5e-25 89.1 7.9 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Actin PF00022.19 EGB08886.1 - 2.8e-73 246.9 0.0 2e-72 244.1 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGB08886.1 - 0.00021 20.2 0.0 0.16 10.7 0.0 2.8 3 0 0 3 3 3 2 MreB/Mbl protein WD40 PF00400.32 EGB08888.1 - 9.6e-21 73.7 29.6 0.057 14.3 0.0 12.5 13 0 0 13 13 13 7 WD domain, G-beta repeat HELP PF03451.14 EGB08888.1 - 1.1e-15 57.2 0.0 2.9e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 HELP motif ANAPC4_WD40 PF12894.7 EGB08888.1 - 2.3e-05 24.6 0.0 0.67 10.3 0.0 5.2 4 2 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 EGB08888.1 - 0.061 12.4 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Kelch_6 PF13964.6 EGB08888.1 - 0.32 11.3 3.2 22 5.5 0.1 4.3 4 0 0 4 4 4 0 Kelch motif AP2 PF00847.20 EGB08889.1 - 6.2e-13 48.8 6.5 1e-05 25.7 0.9 3.5 3 0 0 3 3 3 3 AP2 domain CBS PF00571.28 EGB08890.1 - 7.5e-19 67.9 1.8 5.8e-07 29.9 0.0 4.8 4 1 0 4 4 4 4 CBS domain Cas1_AcylT PF07779.12 EGB08891.1 - 1.2e-11 44.3 3.5 1.3e-06 27.6 0.2 2.2 1 1 1 2 2 2 2 10 TM Acyl Transferase domain found in Cas1p Phage_int_SAM_1 PF02899.17 EGB08891.1 - 0.065 13.5 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain JmjC PF02373.22 EGB08893.1 - 3.3e-20 72.6 0.0 4.3e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGB08893.1 - 2.4e-13 50.4 0.0 9.1e-12 45.2 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EGB08893.1 - 0.027 14.2 0.0 0.071 12.8 0.0 1.7 2 0 0 2 2 2 0 Cupin domain AAA_16 PF13191.6 EGB08894.1 - 0.002 18.5 0.0 0.0026 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGB08894.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGB08894.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Dynamin family NACHT PF05729.12 EGB08894.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 EGB08894.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGB08894.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EGB08894.1 - 0.23 11.2 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Phage_holin_3_6 PF07332.11 EGB08895.1 - 0.016 15.3 1.7 0.016 15.3 1.7 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III UEV PF05743.13 EGB08896.1 - 5e-19 68.4 0.0 5.3e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 EGB08896.1 - 0.0008 19.1 0.0 0.00096 18.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGB08896.1 - 0.0045 17.3 0.0 0.0054 17.0 0.0 1.1 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGB08896.1 - 0.026 14.2 0.1 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B AAA_12 PF13087.6 EGB08897.1 - 6.2e-31 107.6 0.1 6.8e-31 107.5 0.1 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB08897.1 - 0.00094 19.0 0.1 0.0016 18.2 0.1 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGB08897.1 - 0.022 14.5 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase B12-binding PF02310.19 EGB08897.1 - 0.027 14.5 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 B12 binding domain Asp4 PF16996.5 EGB08898.1 - 0.38 10.6 1.2 0.86 9.4 1.2 1.5 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 HSF_DNA-bind PF00447.17 EGB08899.1 - 1.5e-24 86.5 0.0 1.7e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding PD40 PF07676.12 EGB08899.1 - 0.0011 18.9 0.1 0.0075 16.2 0.0 2.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Ank_2 PF12796.7 EGB08900.1 - 2.5e-34 117.7 11.6 2.7e-13 50.3 0.4 4.3 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB08900.1 - 6.3e-27 93.3 24.0 2.4e-08 34.1 1.4 6.6 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB08900.1 - 1.2e-26 92.7 8.6 6.3e-09 36.2 0.1 5.4 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08900.1 - 1.3e-26 89.7 14.4 0.0018 18.6 0.1 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 EGB08900.1 - 2e-18 65.9 24.6 0.027 14.9 0.1 8.5 8 0 0 8 8 8 6 Ankyrin repeat TFIIS_C PF01096.18 EGB08901.1 - 4.3e-15 55.3 1.3 4.3e-15 55.3 1.3 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 EGB08901.1 - 4.4e-06 26.6 7.4 0.00089 19.2 1.2 2.6 2 1 0 2 2 2 2 Double zinc ribbon DNA_RNApol_7kD PF03604.13 EGB08901.1 - 0.00018 21.1 6.6 0.0074 15.9 0.5 3.2 3 0 0 3 3 3 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 EGB08901.1 - 0.00047 19.8 11.2 0.047 13.4 0.1 4.0 4 0 0 4 4 4 2 zinc-ribbon domain HypA PF01155.19 EGB08901.1 - 0.019 15.0 8.2 0.048 13.7 0.4 2.9 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 EGB08901.1 - 0.021 14.3 9.9 0.13 11.7 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain C1_1 PF00130.22 EGB08901.1 - 0.057 13.3 6.4 0.14 12.1 0.7 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_recom PF13408.6 EGB08901.1 - 0.38 11.3 7.7 4.1 8.0 0.2 3.1 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 EGB08901.1 - 0.62 10.2 16.6 1.6 8.9 0.1 3.7 3 1 0 3 3 3 0 Zinc ribbon domain Nudix_N_2 PF14803.6 EGB08901.1 - 0.75 9.8 11.6 5 7.1 0.6 3.5 2 2 0 2 2 2 0 Nudix N-terminal NOB1_Zn_bind PF08772.11 EGB08901.1 - 0.9 9.7 6.2 10 6.3 0.2 3.1 3 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf_UBZ PF18439.1 EGB08901.1 - 1.9 8.1 12.7 4.2 7.0 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 EGB08901.1 - 7.8 6.1 12.1 5.8 6.5 0.1 3.5 3 1 1 4 4 4 0 TFIIB zinc-binding RNA_POL_M_15KD PF02150.16 EGB08901.1 - 7.9 6.5 13.3 2.5 8.1 2.8 3.1 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Myb_DNA-binding PF00249.31 EGB08902.1 - 3.5e-14 52.7 0.2 3.9e-14 52.6 0.2 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB08902.1 - 2.4e-06 27.7 0.2 2.4e-06 27.7 0.2 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB08902.1 - 0.0002 21.2 0.2 0.00021 21.1 0.2 1.1 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EGB08902.1 - 0.063 13.5 0.1 0.063 13.5 0.1 1.1 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Ank_4 PF13637.6 EGB08903.1 - 3.2e-16 59.5 0.5 3.4e-10 40.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB08903.1 - 4.4e-16 58.7 0.8 2.2e-11 43.7 0.1 2.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB08903.1 - 1.2e-14 54.0 0.2 9.8e-08 32.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EGB08903.1 - 3.1e-14 53.3 0.0 1.1e-12 48.4 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB08903.1 - 3.9e-12 45.2 0.0 2.8e-06 27.2 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Cation_efflux PF01545.21 EGB08904.1 - 2.7e-35 121.9 3.9 3.7e-35 121.5 3.9 1.2 1 0 0 1 1 1 1 Cation efflux family Hydrolase_4 PF12146.8 EGB08905.1 - 1.5e-14 53.9 0.1 8.2e-11 41.6 0.2 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB08905.1 - 5.4e-09 36.1 0.5 3.2e-07 30.3 0.5 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGB08905.1 - 0.00014 21.6 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EGB08905.1 - 0.00017 22.3 6.1 0.00021 22.0 5.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EGB08905.1 - 0.00076 19.2 0.0 0.0054 16.4 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EGB08905.1 - 0.065 11.9 0.0 3.1 6.4 0.0 2.4 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.9 EGB08905.1 - 0.17 10.5 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein UBZ_FAAP20 PF15750.5 EGB08905.1 - 3 7.8 6.3 6.4 6.8 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Pkinase PF00069.25 EGB08907.1 - 4.5e-33 114.7 0.0 7.9e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08907.1 - 1.3e-14 54.1 0.0 2.1e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB08907.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldedh PF00171.22 EGB08909.1 - 5.6e-108 361.4 0.6 6.9e-108 361.1 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UFD1 PF03152.14 EGB08910.1 - 3e-70 235.2 0.0 3.7e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA PF00004.29 EGB08911.1 - 9.8e-31 106.9 0.0 5.4e-30 104.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB08911.1 - 9.8e-07 29.3 0.0 5.4e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EGB08911.1 - 1e-06 29.0 0.0 1.4e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGB08911.1 - 1.7e-06 28.3 0.0 2.8e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGB08911.1 - 2e-05 24.6 0.0 0.00011 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGB08911.1 - 0.00079 19.2 0.0 0.0033 17.2 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGB08911.1 - 0.00097 19.3 0.0 0.0019 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGB08911.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB08911.1 - 0.0014 18.2 0.9 0.015 14.9 0.8 2.2 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGB08911.1 - 0.0034 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGB08911.1 - 0.0041 17.5 0.0 0.0079 16.6 0.0 1.5 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.6 EGB08911.1 - 0.006 17.1 0.0 0.011 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EGB08911.1 - 0.0079 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EGB08911.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 EGB08911.1 - 0.052 12.8 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EGB08911.1 - 0.058 13.3 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGB08911.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 EGB08911.1 - 0.062 13.5 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGB08911.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGB08911.1 - 0.088 12.7 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 EGB08911.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB08911.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EGB08911.1 - 0.24 10.7 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 KaiC Pkinase PF00069.25 EGB08912.1 - 4.4e-35 121.3 0.0 5.8e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08912.1 - 6.2e-18 65.0 0.0 6.8e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Response_reg PF00072.24 EGB08912.1 - 3.2e-06 27.3 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase_fungal PF17667.1 EGB08912.1 - 0.019 13.8 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGB08912.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 EGB08914.1 - 6.6e-06 25.7 2.8 0.24 11.3 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB08914.1 - 0.12 12.6 0.1 0.12 12.6 0.1 6.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Myosin_head PF00063.21 EGB08915.1 - 7.6e-213 708.5 0.0 8.7e-213 708.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB08915.1 - 0.0017 18.8 0.0 0.11 12.9 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 EGB08915.1 - 0.082 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 EGB08915.1 - 0.13 11.4 0.1 8.6 5.5 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain Glyco_tran_28_C PF04101.16 EGB08916.1 - 1.3e-19 70.7 0.0 1.6e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SH3_1 PF00018.28 EGB08917.1 - 1.6e-07 30.8 0.1 2.5e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGB08917.1 - 5.6e-06 26.1 0.2 8.3e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGB08917.1 - 0.00023 20.8 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Myosin_head PF00063.21 EGB08918.1 - 6.6e-167 556.7 0.0 1.8e-166 555.3 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EGB08918.1 - 2.5e-06 27.2 1.4 3.1e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 EGB08918.1 - 0.055 13.9 0.4 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 EGB08918.1 - 0.1 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGB08918.1 - 0.22 11.8 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DDE_1 PF03184.19 EGB08920.1 - 0.00037 20.2 0.0 0.00092 18.9 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease KOW PF00467.29 EGB08920.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 KOW motif DHC_N2 PF08393.13 EGB08922.1 - 1.1e-07 31.4 0.1 1.1e-07 31.4 0.1 2.6 2 1 1 3 3 3 1 Dynein heavy chain, N-terminal region 2 Laminin_II PF06009.12 EGB08922.1 - 0.19 11.7 3.7 0.23 11.5 0.0 3.0 3 1 0 3 3 3 0 Laminin Domain II LEA_4 PF02987.16 EGB08922.1 - 6.4 6.9 6.1 19 5.4 0.1 2.9 3 0 0 3 3 3 0 Late embryogenesis abundant protein Ank_2 PF12796.7 EGB08923.1 - 1.7e-16 60.5 0.2 2.2e-16 60.2 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB08923.1 - 6.2e-16 58.5 2.4 3.6e-11 43.4 0.6 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08923.1 - 6e-15 53.9 0.2 1.6e-05 24.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EGB08923.1 - 6.8e-10 38.9 0.5 0.00016 21.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB08923.1 - 2.8e-08 33.9 1.2 0.0001 22.5 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DnaJ PF00226.31 EGB08924.1 - 1.9e-13 50.3 0.0 3.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1771 PF08590.10 EGB08924.1 - 0.25 11.7 8.7 0.86 10.0 2.3 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) cNMP_binding PF00027.29 EGB08925.1 - 3.2e-30 104.1 0.7 7e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4846 PF16138.5 EGB08925.1 - 0.22 11.0 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (4846) PP2C PF00481.21 EGB08926.1 - 2.6e-46 158.4 0.0 3.2e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB08926.1 - 2.3e-07 30.9 0.2 4.1e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGB08926.1 - 1.3e-05 24.9 0.0 2.9e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Acetate_kinase PF00871.17 EGB08926.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Acetokinase family Kinesin PF00225.23 EGB08927.1 - 8.8e-112 373.3 0.1 1.2e-111 372.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB08927.1 - 1.1e-24 87.1 0.1 3e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding DUF1043 PF06295.12 EGB08927.1 - 0.032 14.2 0.4 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) CpxA_peri PF16527.5 EGB08927.1 - 0.53 10.7 3.5 0.73 10.2 0.0 2.7 3 0 0 3 3 3 0 Two-component sensor protein CpxA, periplasmic domain BST2 PF16716.5 EGB08927.1 - 5.1 7.7 9.0 12 6.6 0.9 3.8 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 Abhydrolase_1 PF00561.20 EGB08928.1 - 2.1e-12 47.2 0.0 3.6e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB08928.1 - 1.5e-09 38.8 8.0 1e-08 36.1 8.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB08928.1 - 1.5e-07 31.0 0.0 0.00041 19.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF934 PF06073.12 EGB08929.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) Beta_propel PF09826.9 EGB08930.1 - 3.8e-136 455.0 0.0 4.6e-136 454.7 0.0 1.1 1 0 0 1 1 1 1 Beta propeller domain Glyco_trans_1_4 PF13692.6 EGB08931.1 - 5.4e-17 62.5 0.3 4.6e-16 59.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB08931.1 - 1.1e-12 47.8 0.0 2.4e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 ABC_tran PF00005.27 EGB08932.1 - 1.7e-13 51.2 0.0 5.6e-13 49.6 0.0 1.6 1 1 1 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGB08932.1 - 5e-05 23.3 1.4 0.067 13.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB08932.1 - 6.1e-05 22.7 0.1 0.00017 21.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB08932.1 - 0.0017 18.8 0.7 0.0033 17.8 0.7 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGB08932.1 - 0.0021 18.0 0.2 0.0034 17.3 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EGB08932.1 - 0.0051 16.3 0.0 0.025 14.0 0.0 1.8 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGB08932.1 - 0.0053 17.3 0.1 0.0073 16.8 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB08932.1 - 0.0074 16.6 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB08932.1 - 0.013 15.6 0.2 0.023 14.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB08932.1 - 0.046 13.4 0.7 0.076 12.7 0.6 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGB08932.1 - 0.06 12.9 0.5 0.1 12.2 0.5 1.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGB08932.1 - 0.063 12.3 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 EGB08932.1 - 0.08 12.5 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGB08932.1 - 0.17 12.0 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EGB08932.1 - 0.21 12.2 0.0 0.46 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Anoctamin PF04547.12 EGB08933.1 - 5.4e-73 246.4 5.8 1.2e-47 162.8 0.1 2.0 1 1 1 2 2 2 2 Calcium-activated chloride channel AA_permease_2 PF13520.6 EGB08933.1 - 0.97 8.2 5.6 0.13 11.0 1.4 1.6 2 0 0 2 2 2 0 Amino acid permease Glyoxalase PF00903.25 EGB08934.1 - 5e-21 75.2 0.0 6.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGB08934.1 - 7e-08 33.2 0.0 2.4e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EGB08934.1 - 3.4e-05 24.1 0.0 0.0024 18.1 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DSPc PF00782.20 EGB08935.1 - 1.8e-18 66.7 0.0 1.9e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RGS PF00615.19 EGB08936.1 - 8.1e-08 32.6 0.3 1.4e-07 31.8 0.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain cNMP_binding PF00027.29 EGB08936.1 - 0.0026 17.8 0.0 0.0073 16.4 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MFS_1 PF07690.16 EGB08937.1 - 2.9e-19 69.2 13.6 4.1e-19 68.7 13.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EGB08937.1 - 0.0013 17.7 1.5 0.0017 17.3 1.5 1.3 1 0 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 EGB08937.1 - 0.0015 17.4 6.3 0.0022 16.9 6.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Band_7 PF01145.25 EGB08938.1 - 1.5e-20 73.9 0.0 1.9e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF1974 PF09317.11 EGB08938.1 - 0.022 14.3 0.1 0.089 12.3 0.0 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF1974) IQ PF00612.27 EGB08939.1 - 6.7e-09 34.8 5.5 0.0013 18.3 0.2 3.3 1 1 1 2 2 2 2 IQ calmodulin-binding motif SHOCT PF09851.9 EGB08939.1 - 0.0023 17.6 0.1 0.0079 15.9 0.1 2.0 1 0 0 1 1 1 1 Short C-terminal domain MAS20 PF02064.15 EGB08939.1 - 0.003 17.6 2.1 0.0049 17.0 2.1 1.2 1 0 0 1 1 1 1 MAS20 protein import receptor SART-1 PF03343.13 EGB08939.1 - 0.031 12.9 5.8 0.04 12.5 5.8 1.1 1 0 0 1 1 1 0 SART-1 family BT1 PF03092.16 EGB08939.1 - 0.13 10.5 0.4 0.17 10.1 0.4 1.0 1 0 0 1 1 1 0 BT1 family RBFA PF02033.18 EGB08940.1 - 4.8e-14 52.7 0.3 6.5e-14 52.3 0.3 1.2 1 0 0 1 1 1 1 Ribosome-binding factor A ORC2 PF04084.14 EGB08941.1 - 2.4e-45 154.9 0.0 4.1e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 SHIPPO-rpt PF07004.12 EGB08941.1 - 0.00067 20.4 20.2 18 6.4 0.0 7.7 7 0 0 7 7 7 2 Sperm-tail PG-rich repeat CoA_binding_3 PF13727.6 EGB08941.1 - 0.069 13.2 1.4 18 5.3 0.0 3.6 4 0 0 4 4 4 0 CoA-binding domain Tho2 PF11262.8 EGB08941.1 - 0.11 11.7 0.7 0.17 11.1 0.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PI3K_P85_iSH2 PF16454.5 EGB08941.1 - 4.1 7.0 8.4 7 6.2 8.4 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4200 PF13863.6 EGB08941.1 - 4.3 7.8 9.1 10 6.6 9.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PSI_PsaE PF02427.17 EGB08942.1 - 1.9e-32 110.7 0.9 2.2e-32 110.5 0.9 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IV / PsaE RCC1 PF00415.18 EGB08943.1 - 5.2e-19 68.6 12.0 0.00034 21.2 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat MT-A70 PF05063.14 EGB08943.1 - 1.4e-14 54.4 0.0 5.1e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 MT-A70 RCC1_2 PF13540.6 EGB08943.1 - 4e-09 36.0 20.5 0.00036 20.2 1.5 4.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Glyco_trans_1_2 PF13524.6 EGB08943.1 - 4e-05 23.9 0.8 0.0018 18.6 0.0 3.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Ank_2 PF12796.7 EGB08943.1 - 0.00064 20.3 0.0 0.17 12.5 0.0 3.0 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB08943.1 - 0.014 15.7 0.1 16 5.9 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB08943.1 - 0.031 14.9 0.3 14 6.4 0.1 3.6 4 0 0 4 4 4 0 Ankyrin repeats (many copies) EamA PF00892.20 EGB08944.1 - 1.1e-21 77.4 18.4 1.5e-15 57.5 0.2 3.4 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 EGB08944.1 - 5.4e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 Triose-phosphate Transporter family Hepsin-SRCR PF09272.10 EGB08944.1 - 0.022 15.2 0.0 0.039 14.5 0.0 1.3 1 0 0 1 1 1 0 Hepsin, SRCR domain UAA PF08449.11 EGB08944.1 - 0.041 13.1 0.0 0.041 13.1 0.0 2.2 3 0 0 3 3 3 0 UAA transporter family BORCS8 PF10167.9 EGB08945.1 - 2.3 8.2 6.7 1.9 8.5 1.6 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 SNF2_N PF00176.23 EGB08947.1 - 4.2e-59 200.0 0.0 6.1e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB08947.1 - 7.6e-19 68.1 0.0 1.2e-17 64.2 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB08947.1 - 2.4e-06 27.7 0.0 6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGB08947.1 - 6.9e-05 22.1 0.0 0.00014 21.1 0.0 1.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_19 PF13245.6 EGB08947.1 - 0.082 13.2 0.0 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EGB08947.1 - 1.5 8.1 4.6 2.6 7.3 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4 PF00097.25 EGB08948.1 - 0.00091 19.1 5.0 0.0014 18.5 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB08948.1 - 0.0018 18.3 0.8 0.0033 17.4 0.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGB08948.1 - 0.0018 18.4 4.4 0.0028 17.8 4.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGB08948.1 - 0.0029 17.4 5.5 0.005 16.7 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB08948.1 - 0.0031 17.4 4.6 0.0051 16.8 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGB08948.1 - 0.014 15.2 5.8 0.025 14.4 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB08948.1 - 0.027 14.8 5.7 0.043 14.1 5.7 1.3 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 EGB08948.1 - 0.63 9.9 5.3 1.3 9.0 5.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DHC_N1 PF08385.12 EGB08949.1 - 3.5e-175 583.9 9.2 1e-174 582.3 9.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EGB08949.1 - 1e-144 481.5 0.0 5e-144 479.2 0.0 2.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB08949.1 - 1.1e-102 344.2 0.1 1.1e-102 344.2 0.1 2.8 4 0 0 4 4 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGB08949.1 - 4.1e-88 295.1 0.2 1.1e-87 293.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGB08949.1 - 2.6e-81 273.2 0.0 1.3e-80 270.9 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGB08949.1 - 2.9e-74 248.9 0.7 1e-73 247.1 0.8 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGB08949.1 - 1.5e-58 197.3 3.9 1.8e-53 180.8 0.0 4.7 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB08949.1 - 4.7e-48 163.1 0.0 9.4e-48 162.1 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGB08949.1 - 1.2e-37 129.8 10.2 2e-37 129.0 10.2 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGB08949.1 - 1.2e-35 122.2 0.0 6e-35 119.9 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EGB08949.1 - 9.6e-19 67.8 0.1 4e-09 36.6 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGB08949.1 - 2.8e-14 53.2 0.0 1.3e-13 51.0 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EGB08949.1 - 7.4e-13 48.7 0.0 3e-12 46.8 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EGB08949.1 - 5.6e-08 33.3 1.1 0.39 11.1 0.0 6.4 5 1 0 5 5 4 2 AAA ATPase domain AAA PF00004.29 EGB08949.1 - 1.2e-07 32.2 3.2 0.23 11.9 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB08949.1 - 3.6e-06 27.3 0.1 1.7 8.9 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 EGB08949.1 - 4.2e-06 27.3 0.2 0.15 12.6 0.0 4.4 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 EGB08949.1 - 1.8e-05 24.9 0.1 0.017 15.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EGB08949.1 - 0.0003 21.3 0.1 0.035 14.6 0.0 3.9 4 0 0 4 4 4 1 ABC transporter AAA_29 PF13555.6 EGB08949.1 - 0.00034 20.3 0.1 0.022 14.5 0.0 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGB08949.1 - 0.0021 17.5 1.1 0.0077 15.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGB08949.1 - 0.0052 17.0 0.5 7.1 6.8 0.0 4.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGB08949.1 - 0.0052 17.1 0.0 0.52 10.7 0.0 3.3 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EGB08949.1 - 0.0056 16.6 0.0 0.3 11.0 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 EGB08949.1 - 0.012 15.9 3.0 0.83 10.0 0.0 4.2 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 EGB08949.1 - 0.023 14.0 0.2 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EGB08949.1 - 0.049 13.4 9.6 0.049 13.3 0.0 3.8 5 0 0 5 5 4 0 AAA domain RuvB_N PF05496.12 EGB08949.1 - 0.051 13.3 0.1 9.7 5.9 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain SLATT_5 PF18160.1 EGB08949.1 - 0.14 11.5 2.5 0.29 10.5 2.5 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 AAA_24 PF13479.6 EGB08949.1 - 0.22 11.2 1.3 10 5.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 EGB08949.1 - 0.68 10.4 0.0 0.68 10.4 0.0 4.7 4 1 0 4 4 3 0 AAA domain DnaJ PF00226.31 EGB08951.1 - 3.6e-22 78.3 0.2 4.2e-22 78.0 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain UvrD-helicase PF00580.21 EGB08953.1 - 1e-48 166.5 0.0 2.4e-46 158.7 0.0 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EGB08953.1 - 1.8e-37 129.6 0.0 2.5e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EGB08953.1 - 1.3e-25 90.4 0.0 2.8e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB08953.1 - 3.8e-09 36.2 0.2 0.00026 20.7 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EGB08953.1 - 6.3e-07 29.3 2.2 1.5e-05 24.8 1.0 2.9 1 1 0 1 1 1 1 AAA domain Exonuc_V_gamma PF04257.14 EGB08953.1 - 0.00023 19.5 0.0 0.0018 16.6 0.0 2.0 2 0 0 2 2 2 1 Exodeoxyribonuclease V, gamma subunit Dimer_Tnp_Tn5 PF02281.16 EGB08954.1 - 0.095 12.4 0.1 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain Abhydrolase_3 PF07859.13 EGB08955.1 - 6.8e-38 130.7 0.1 1.3e-37 129.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGB08955.1 - 0.0031 16.4 0.0 0.023 13.6 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Iso_dh PF00180.20 EGB08957.1 - 1.4e-15 57.3 0.0 2.9e-15 56.3 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_1 PF00036.32 EGB08957.1 - 5.3e-08 31.9 1.7 8.1e-08 31.3 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGB08957.1 - 4.9e-07 29.5 0.1 2.4e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB08957.1 - 3.2e-06 26.4 1.4 1.4e-05 24.4 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGB08957.1 - 2.5e-05 24.6 0.0 6.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB08957.1 - 0.0001 21.9 0.0 0.00049 19.8 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain DnaJ PF00226.31 EGB08958.1 - 1.7e-10 40.8 0.5 2.9e-10 40.1 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.27 EGB08959.1 - 1.8e-14 53.4 5.7 8.4e-06 25.6 0.1 4.5 3 1 1 4 4 4 3 Mitochondrial carrier protein DUF615 PF04751.14 EGB08959.1 - 9.7 6.2 11.9 10 6.0 6.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF615) ABC1 PF03109.16 EGB08960.1 - 2.6e-25 88.9 0.0 4.9e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB08960.1 - 4.1e-07 30.2 7.8 3.8e-06 27.0 7.7 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB08960.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NUDIX PF00293.28 EGB08961.1 - 4.1e-13 49.5 0.0 4.1e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain AAA_19 PF13245.6 EGB08961.1 - 9e-06 26.1 0.3 2.9e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EGB08961.1 - 0.0067 16.0 0.0 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF4703 PF15775.5 EGB08961.1 - 1.2 8.9 4.7 2.6 7.8 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Aconitase_2_N PF06434.13 EGB08962.1 - 3.5e-93 310.9 0.0 5.6e-93 310.2 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 EGB08962.1 - 5.3e-60 202.0 0.1 9.8e-60 201.1 0.1 1.4 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 EGB08962.1 - 5.6e-42 144.3 0.0 3.5e-40 138.4 0.0 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) AAA_5 PF07728.14 EGB08964.1 - 7.7e-75 249.5 0.0 8.8e-28 97.0 0.0 3.3 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB08964.1 - 0.00024 21.5 7.7 0.57 10.5 0.0 5.8 5 1 1 6 6 6 1 AAA ATPase domain AAA_22 PF13401.6 EGB08964.1 - 0.003 17.9 0.1 0.19 12.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGB08964.1 - 0.0032 16.9 0.1 0.026 13.9 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI CbbQ_C PF08406.10 EGB08964.1 - 0.025 14.8 0.1 2.7 8.3 0.0 3.4 3 0 0 3 3 3 0 CbbQ/NirQ/NorQ C-terminal VWA PF00092.28 EGB08964.1 - 0.025 14.8 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA PF00004.29 EGB08964.1 - 0.042 14.3 0.0 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGB08964.1 - 0.077 13.1 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Aconitase_B_N PF11791.8 EGB08965.1 - 5.4e-29 101.2 0.1 5.9e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Aconitate B N-terminal domain NUC202 PF08166.12 EGB08965.1 - 0.13 12.3 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 NUC202 domain PH PF00169.29 EGB08966.1 - 2.1e-15 57.1 0.1 2.4e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGB08966.1 - 4.6e-06 27.0 1.1 0.00012 22.4 1.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EGB08966.1 - 0.00017 21.6 0.0 0.00021 21.3 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGB08966.1 - 0.00019 21.8 0.1 0.0029 18.0 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EGB08966.1 - 0.00032 20.9 0.0 0.0004 20.6 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 EGB08966.1 - 0.06 13.2 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 EGB08966.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 EGB08966.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Plant pleckstrin homology-like region GTP_EFTU PF00009.27 EGB08967.1 - 5e-25 88.2 0.0 6.5e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGB08967.1 - 0.00012 22.3 0.0 0.00031 21.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGB08967.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EGB08967.1 - 0.0024 18.2 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.9 EGB08967.1 - 0.021 14.5 0.1 23 4.7 0.0 3.4 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGB08967.1 - 0.06 13.3 0.3 3.1 7.7 0.3 2.3 2 0 0 2 2 2 0 RsgA GTPase PRKCSH PF07915.13 EGB08968.1 - 1.1e-19 71.1 4.3 9.1e-10 39.4 0.1 3.0 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGB08968.1 - 5.8e-13 48.8 3.3 5.5e-09 35.9 0.0 3.0 1 1 1 2 2 2 2 Glucosidase II beta subunit-like protein Stk19 PF10494.9 EGB08969.1 - 4.1e-16 59.4 0.0 7.6e-15 55.3 0.0 2.4 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 zf-RanBP PF00641.18 EGB08970.1 - 0.017 14.4 0.8 0.03 13.6 0.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others SRAP PF02586.14 EGB08970.1 - 0.092 12.3 0.0 0.48 9.9 0.0 2.0 1 1 0 1 1 1 0 SOS response associated peptidase (SRAP) DZR PF12773.7 EGB08970.1 - 0.17 11.9 0.9 0.38 10.8 0.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon SR-25 PF10500.9 EGB08970.1 - 0.55 9.8 3.5 0.87 9.1 3.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zinc_ribbon_9 PF14369.6 EGB08970.1 - 6.1 7.2 6.9 11 6.4 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon Pro-kuma_activ PF09286.11 EGB08971.1 - 1.7e-21 77.0 0.0 2.6e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGB08971.1 - 0.00041 19.7 0.3 0.00082 18.7 0.3 1.4 1 0 0 1 1 1 1 Subtilase family 7TMR-DISM_7TM PF07695.11 EGB08971.1 - 0.034 14.0 4.5 0.057 13.3 4.5 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling Pkinase PF00069.25 EGB08972.1 - 1e-60 205.4 0.0 1.5e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EGB08972.1 - 5.3e-37 125.8 0.1 1.9e-15 56.7 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGB08972.1 - 1.6e-31 109.5 0.1 3.1e-31 108.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase GARS_C PF02843.16 EGB08972.1 - 0.073 13.4 0.0 1.1 9.5 0.0 2.7 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain APH PF01636.23 EGB08972.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF547 PF04784.14 EGB08973.1 - 1.4e-15 57.4 0.0 3.2e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF547 DENN PF02141.21 EGB08973.1 - 1.5e-09 38.1 0.0 3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain RSRP PF17069.5 EGB08973.1 - 0.14 11.7 44.7 0.25 10.9 44.7 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Apt1 PF10351.9 EGB08973.1 - 2.1 7.1 10.7 3 6.6 10.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Usp PF00582.26 EGB08973.1 - 2.4 8.7 10.0 16 6.0 0.0 4.5 4 0 0 4 4 4 0 Universal stress protein family DUF2992 PF11208.8 EGB08973.1 - 6 7.1 16.0 10 6.4 16.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SOBP PF15279.6 EGB08973.1 - 6.9 7.2 10.6 11 6.5 10.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Spem1 PF15670.5 EGB08973.1 - 8.4 5.9 10.6 14 5.2 10.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 DNA_pol_A_exo1 PF01612.20 EGB08974.1 - 1.2e-23 83.7 0.0 2.8e-23 82.5 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 EGB08974.1 - 3.1e-08 33.5 1.2 7.8e-08 32.2 0.1 2.1 2 0 0 2 2 2 1 HRDC domain R3H PF01424.22 EGB08974.1 - 0.00019 21.3 0.0 0.00081 19.3 0.0 2.0 2 0 0 2 2 2 1 R3H domain AAA_16 PF13191.6 EGB08975.1 - 4.4e-09 37.0 4.8 5.2e-06 26.9 0.1 3.6 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 EGB08975.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 NACHT domain Mitoc_mL59 PF18126.1 EGB08975.1 - 0.21 11.9 1.9 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein mL59 Pkinase PF00069.25 EGB08976.1 - 8.2e-72 241.7 0.0 9.5e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB08976.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGB08976.1 - 0.01 15.5 0.1 3.5 7.2 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGB08976.1 - 0.011 15.1 0.2 0.021 14.1 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGB08976.1 - 0.027 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 EGB08976.1 - 0.067 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EGB08976.1 - 0.11 12.5 0.0 0.46 10.4 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 EGB08977.1 - 2.2e-12 47.2 0.0 4.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family KIAA1430 PF13879.6 EGB08978.1 - 2.6e-16 60.2 0.3 4.5e-16 59.5 0.3 1.4 1 0 0 1 1 1 1 KIAA1430 homologue EF-hand_6 PF13405.6 EGB08978.1 - 0.0022 17.8 0.1 4.4 7.5 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 EGB08978.1 - 0.0035 17.7 0.0 0.057 13.9 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB08978.1 - 0.064 12.8 0.0 4.1 7.2 0.0 3.5 4 0 0 4 4 4 0 EF hand RmlD_sub_bind PF04321.17 EGB08979.1 - 9e-12 44.7 0.0 1.1e-11 44.4 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGB08979.1 - 8.3e-07 28.7 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGB08979.1 - 0.001 18.2 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGB08979.1 - 0.01 15.3 0.0 0.025 14.0 0.0 1.5 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase Latrotoxin_C PF15658.6 EGB08979.1 - 0.036 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Latrotoxin C-terminal domain zf-MYND PF01753.18 EGB08980.1 - 0.21 11.7 18.2 0.024 14.7 13.8 1.7 2 0 0 2 2 2 0 MYND finger DUF678 PF05077.12 EGB08980.1 - 7.2 6.8 5.9 0.79 9.9 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF678) tRNA-synt_1e PF01406.19 EGB08981.1 - 3.8e-110 368.0 0.0 5.6e-110 367.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGB08981.1 - 1.5e-10 40.4 0.1 5.2e-07 28.7 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 EGB08981.1 - 0.041 12.8 0.0 0.091 11.6 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF2508 PF10704.9 EGB08981.1 - 3.7 7.8 8.5 16 5.8 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) Ank_2 PF12796.7 EGB08982.1 - 3.2e-17 62.9 0.1 7.9e-17 61.6 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGB08982.1 - 1.7e-14 53.5 1.3 3.6e-07 30.3 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB08982.1 - 4.1e-14 52.4 3.6 2.3e-07 31.0 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB08982.1 - 2.4e-13 50.3 2.3 6e-10 39.5 0.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB08982.1 - 1e-11 43.9 0.3 0.00012 22.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat SEP PF08059.13 EGB08983.1 - 2.4e-13 50.4 0.0 6.5e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EGB08983.1 - 7.8e-05 22.8 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain HrpB7 PF09486.10 EGB08983.1 - 0.0011 19.3 1.9 0.003 18.0 1.8 1.8 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 EGB08983.1 - 0.0025 18.1 2.0 0.0041 17.4 2.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EGB08983.1 - 0.0069 16.6 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding LRRFIP PF09738.9 EGB08983.1 - 0.035 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 LRRFIP family TMF_DNA_bd PF12329.8 EGB08983.1 - 0.18 11.8 0.1 0.51 10.4 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 EGB08983.1 - 0.28 10.2 0.1 0.41 9.7 0.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Senescence PF06911.12 EGB08984.1 - 0.13 12.6 18.7 0.5 10.7 13.3 3.2 2 1 1 3 3 3 0 Senescence-associated protein TPR_2 PF07719.17 EGB08985.1 - 6.3e-05 22.8 0.2 0.015 15.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB08985.1 - 0.0072 16.1 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SBP_bac_3 PF00497.20 EGB08985.1 - 0.032 13.6 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Mpv17_PMP22 PF04117.12 EGB08988.1 - 2e-17 63.1 1.0 3.7e-17 62.3 1.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TPR_12 PF13424.6 EGB08990.1 - 0.00049 20.3 9.0 0.0046 17.2 0.8 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB08990.1 - 0.00051 20.0 11.8 0.0087 16.1 0.6 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB08990.1 - 0.00057 20.5 7.4 0.00057 20.5 7.4 4.3 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGB08990.1 - 0.00085 19.4 5.6 0.00085 19.4 5.6 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ubiquitin PF00240.23 EGB08990.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TPR_1 PF00515.28 EGB08990.1 - 0.021 14.6 0.4 0.021 14.6 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB08990.1 - 0.099 13.1 0.1 4.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PgaPase_1 PF06162.12 EGB08990.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 TPR_11 PF13414.6 EGB08990.1 - 0.58 9.9 3.4 15 5.4 0.1 2.7 2 1 1 3 3 3 0 TPR repeat ABC_membrane PF00664.23 EGB08991.1 - 3.1e-41 141.9 8.9 3.8e-41 141.6 8.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB08991.1 - 1.1e-27 97.2 0.0 2e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGB08991.1 - 3.6e-05 23.3 0.4 0.0019 17.7 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB08991.1 - 0.0012 19.3 0.2 0.003 18.0 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 EGB08991.1 - 0.0026 18.0 4.4 0.0066 16.7 0.9 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EGB08991.1 - 0.0054 16.3 0.2 0.9 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGB08991.1 - 0.013 15.7 0.3 0.095 13.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGB08991.1 - 0.014 15.1 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB08991.1 - 0.036 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 EGB08991.1 - 0.078 13.1 0.0 0.6 10.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Carb_anhydrase PF00194.21 EGB08992.1 - 1.4e-39 136.1 0.0 4.2e-39 134.6 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic-type carbonic anhydrase Na_H_Exchanger PF00999.21 EGB08992.1 - 6.6e-13 48.2 3.0 1.3e-07 30.8 0.1 2.2 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family DUF2680 PF10925.8 EGB08992.1 - 0.0018 18.2 0.5 0.0018 18.2 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2680) Porin_5 PF16930.5 EGB08992.1 - 0.048 12.2 1.0 0.069 11.6 1.0 1.2 1 0 0 1 1 1 0 Putative porin Spc7 PF08317.11 EGB08993.1 - 0.15 10.9 0.6 0.21 10.5 0.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DHR10 PF18595.1 EGB08993.1 - 0.27 11.3 4.3 0.46 10.6 4.3 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Kinesin PF00225.23 EGB08994.1 - 9.8e-91 304.1 0.0 1.1e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB08994.1 - 1.4e-22 80.3 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 EGB08994.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase PABP PF00658.18 EGB08995.1 - 3.3e-19 68.8 0.0 3.4e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain PseudoU_synth_2 PF00849.22 EGB08996.1 - 1.2e-26 93.7 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EGB08996.1 - 4.7e-08 32.6 0.0 1.5e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 EGB08996.1 - 0.0018 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain BPL_LplA_LipB PF03099.19 EGB08997.1 - 0.0055 16.6 0.0 0.023 14.6 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TUDOR_5 PF18359.1 EGB08998.1 - 5.4e-111 362.2 133.1 8.8e-08 31.7 0.9 16.4 16 0 0 16 16 16 16 Histone methyltransferase Tudor domain 1 53-BP1_Tudor PF09038.10 EGB08998.1 - 3.9e-69 230.2 52.1 0.0016 18.4 0.0 16.2 16 0 0 16 16 16 16 Tumour suppressor p53-binding protein-1 Tudor DUF1325 PF07039.11 EGB08998.1 - 9.7e-47 158.4 28.1 0.037 14.1 0.0 16.0 2 2 14 16 16 16 15 SGF29 tudor-like domain LBR_tudor PF09465.10 EGB08998.1 - 1.2e-37 127.5 45.7 0.18 11.6 0.0 16.3 16 0 0 16 16 16 16 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 EGB08998.1 - 8.4e-33 113.0 32.5 0.0012 18.9 0.3 11.0 6 2 5 12 12 12 10 Domain of unknown function (DUF4537) Agenet PF05641.12 EGB08998.1 - 6.8e-19 68.1 59.4 0.0016 18.8 0.1 16.3 16 0 0 16 16 16 6 Agenet domain Tcp10_C PF07202.13 EGB08998.1 - 1.7e-07 31.4 34.2 4.3 7.3 0.4 13.4 7 4 6 13 13 13 4 T-complex protein 10 C-terminus Filamin PF00630.19 EGB08998.1 - 0.00027 21.7 49.6 86 4.0 0.1 14.3 6 3 0 9 9 8 0 Filamin/ABP280 repeat CHCH PF06747.13 EGB08998.1 - 0.002 18.2 0.3 0.0037 17.3 0.3 1.5 1 0 0 1 1 1 1 CHCH domain DPPIV_N PF00930.21 EGB08998.1 - 0.014 14.2 5.0 46 2.6 0.0 7.0 2 1 8 11 11 11 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DEC-1_N PF04625.13 EGB08998.1 - 0.35 9.8 18.6 0.91 8.5 18.6 1.6 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Bac_A_amyl_C PF18612.1 EGB08998.1 - 1.7 8.5 46.3 8 6.3 0.1 12.0 13 0 0 13 13 13 0 Bacterial Alpha amylase C-terminal domain TAL_FSA PF00923.19 EGB08999.1 - 2.5e-77 260.1 0.0 3.2e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Aldo_ket_red PF00248.21 EGB09000.1 - 6.2e-27 94.6 0.0 1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family PrmA PF06325.13 EGB09000.1 - 4.6e-08 32.8 0.7 7.8e-08 32.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGB09000.1 - 4.6e-08 33.7 0.2 1.4e-07 32.1 0.2 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB09000.1 - 1.1e-06 28.3 0.1 2.2e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGB09000.1 - 6.7e-05 23.5 0.1 0.00017 22.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGB09000.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EGB09000.1 - 0.00078 19.3 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGB09000.1 - 0.0051 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09000.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EGB09000.1 - 0.014 15.2 0.2 0.023 14.5 0.2 1.2 1 0 0 1 1 1 0 Met-10+ like-protein WWE PF02825.20 EGB09000.1 - 0.036 14.6 0.0 0.1 13.2 0.0 1.8 2 0 0 2 2 1 0 WWE domain Methyltransf_9 PF08003.11 EGB09000.1 - 0.19 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pyr_redox_2 PF07992.14 EGB09001.1 - 4.7e-38 131.1 0.1 6.6e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB09001.1 - 4.9e-19 68.6 0.0 1.2e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB09001.1 - 5.1e-11 43.0 0.1 1e-10 42.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB09001.1 - 0.00023 20.5 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB09001.1 - 0.0057 15.8 0.0 0.023 13.8 0.0 1.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EGB09001.1 - 0.032 13.3 1.6 15 4.5 0.0 3.3 3 1 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EGB09001.1 - 0.14 12.6 0.1 0.37 11.3 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding CENP-T_C PF15511.6 EGB09002.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB09002.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB09002.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB09002.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB09002.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB09002.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB09002.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGB09002.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EGB09003.1 - 3.9e-16 59.6 0.5 4.8e-16 59.3 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB09003.1 - 0.0038 17.5 0.1 0.0098 16.2 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB09003.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A adh_short_C2 PF13561.6 EGB09004.1 - 6.2e-50 169.9 6.6 7.4e-50 169.7 6.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB09004.1 - 2e-43 148.1 3.2 2.7e-43 147.7 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB09004.1 - 5.3e-07 29.7 3.6 1.1e-06 28.7 3.6 1.6 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EGB09004.1 - 3.2e-05 23.2 1.4 5.4e-05 22.4 1.4 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGB09004.1 - 0.00032 20.3 0.3 0.0011 18.5 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB09004.1 - 0.0069 16.3 0.8 0.014 15.3 0.8 1.6 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EGB09004.1 - 0.0094 16.5 0.4 0.02 15.5 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent LRR_6 PF13516.6 EGB09005.1 - 8.8e-29 97.1 12.8 4.3e-06 26.4 0.0 9.1 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 EGB09005.1 - 0.00013 22.3 0.1 5.5 7.6 0.0 4.5 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB09005.1 - 0.00023 21.3 0.0 36 5.4 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 EGB09005.1 - 0.00061 19.5 2.7 6.9 6.5 0.1 5.1 4 3 0 4 4 4 2 Leucine rich repeat Kelch_1 PF01344.25 EGB09006.1 - 1.1e-14 53.7 10.3 1.3e-05 24.7 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EGB09006.1 - 1.6e-13 50.0 3.4 0.021 14.8 0.1 5.1 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 EGB09006.1 - 3.4e-13 49.2 7.2 0.0013 18.7 0.1 5.7 5 0 0 5 5 5 4 Kelch motif MatE PF01554.18 EGB09006.1 - 3.5e-13 49.5 13.5 9.9e-08 31.8 7.6 2.4 1 1 1 2 2 2 2 MatE Kelch_6 PF13964.6 EGB09006.1 - 2.2e-12 46.8 2.3 0.012 15.9 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EGB09006.1 - 1.3e-08 34.7 15.1 1.3e-05 25.1 0.4 5.2 5 2 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EGB09006.1 - 5.7e-08 32.9 15.3 0.066 13.5 0.2 5.8 4 2 0 4 4 4 3 Galactose oxidase, central domain ubiquitin PF00240.23 EGB09007.1 - 5.3e-24 83.8 0.8 5.8e-24 83.6 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB09007.1 - 8.1e-12 44.8 0.6 8.9e-12 44.7 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGB09007.1 - 0.00029 21.1 0.2 0.00031 21.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EGB09007.1 - 0.0015 18.9 0.2 0.0056 17.1 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB09007.1 - 0.0091 16.1 0.0 0.014 15.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGB09007.1 - 0.041 14.4 0.0 0.051 14.1 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WD40 PF00400.32 EGB09008.1 - 1.7e-13 50.8 20.9 0.01 16.7 0.5 9.6 12 0 0 12 12 12 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09008.1 - 1.2e-05 25.5 0.0 1.8 8.9 0.0 6.6 6 1 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EGB09008.1 - 0.014 14.7 0.0 0.14 11.4 0.0 2.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.6 EGB09008.1 - 5.5 7.6 19.2 9.3 6.9 0.0 7.9 9 0 0 9 9 9 0 PQQ-like domain ABC1 PF03109.16 EGB09010.1 - 2.6e-20 72.7 0.0 3.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGB09010.1 - 0.00095 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family cobW PF02492.19 EGB09011.1 - 2.3e-54 183.6 0.3 3e-54 183.3 0.3 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB09011.1 - 8.4e-22 76.9 0.0 1.7e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 EGB09011.1 - 0.00013 21.6 0.1 0.17 11.4 0.1 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB09011.1 - 0.00037 20.4 0.2 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 EGB09011.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGB09011.1 - 0.0032 17.7 0.1 0.057 13.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB09011.1 - 0.0036 17.7 0.2 0.01 16.2 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EGB09011.1 - 0.0038 17.4 0.0 0.0084 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGB09011.1 - 0.0042 17.2 0.3 0.031 14.3 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 EGB09011.1 - 0.046 13.6 0.1 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 EGB09011.1 - 0.055 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 EGB09011.1 - 0.063 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 EGB09011.1 - 0.1 12.1 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 EGB09011.1 - 0.11 11.7 0.0 0.27 10.5 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin Roc PF08477.13 EGB09011.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB09011.1 - 0.13 11.7 0.5 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 EGB09011.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB09011.1 - 0.19 12.2 0.0 0.45 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGB09011.1 - 0.28 11.0 1.7 0.28 10.9 0.1 1.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain Glyco_transf_7N PF13733.6 EGB09012.1 - 6.5e-14 51.7 0.1 3.3e-13 49.4 0.1 1.9 1 1 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 EGB09012.1 - 4e-11 42.4 0.1 6.1e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 EGB09012.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Pkinase PF00069.25 EGB09013.1 - 1.4e-48 165.6 0.0 2.7e-48 164.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09013.1 - 3.2e-30 105.3 0.0 6e-30 104.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09013.1 - 5.7e-06 25.9 0.0 9.6e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB09013.1 - 0.00031 20.2 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB09013.1 - 0.00055 19.9 0.4 0.00092 19.2 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB09013.1 - 0.00095 18.0 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DEAD PF00270.29 EGB09014.1 - 7.8e-41 139.7 0.0 1.2e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB09014.1 - 7.5e-30 103.5 0.0 1.3e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGB09014.1 - 7.8e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Sigma70_r3 PF04539.16 EGB09014.1 - 0.00016 21.7 0.4 0.00033 20.7 0.4 1.4 1 0 0 1 1 1 1 Sigma-70 region 3 ResIII PF04851.15 EGB09014.1 - 0.0079 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BBS2_C PF14782.6 EGB09015.1 - 4.2e-132 441.0 0.0 6.3e-132 440.4 0.0 1.3 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 EGB09015.1 - 1.1e-36 125.1 0.0 4.1e-36 123.3 0.0 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 EGB09015.1 - 1.4e-30 105.2 0.0 6.3e-30 103.2 0.0 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 EGB09015.1 - 0.0004 19.5 0.0 0.0025 16.9 0.0 2.0 1 1 1 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 DUF4140 PF13600.6 EGB09015.1 - 0.4 11.2 2.4 1.2 9.7 0.1 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DSBA PF01323.20 EGB09015.1 - 1.2 8.8 3.7 2.2 8.0 1.8 2.2 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Glyco_tranf_2_2 PF10111.9 EGB09016.1 - 1e-05 25.2 0.0 0.0024 17.4 0.0 2.6 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGB09016.1 - 0.00023 21.0 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB09016.1 - 0.0028 17.6 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 2-Hacid_dh_C PF02826.19 EGB09017.1 - 5.8e-26 90.9 0.0 6.7e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Chloroa_b-bind PF00504.21 EGB09018.1 - 3.1e-32 112.3 0.0 4.2e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 EGB09019.1 - 1.3e-34 120.1 0.1 1.7e-34 119.6 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DEC-1_N PF04625.13 EGB09019.1 - 0.16 11.0 1.9 0.22 10.5 1.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SfsA PF03749.13 EGB09020.1 - 4.4e-18 65.5 0.0 8.8e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Sugar fermentation stimulation protein RE domain eIF-3c_N PF05470.12 EGB09021.1 - 1e-172 575.6 0.2 1.4e-172 575.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGB09021.1 - 6.8e-09 36.2 0.0 2e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 PCI domain SAPS PF04499.15 EGB09021.1 - 0.41 9.4 8.2 0.87 8.3 8.2 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dicty_REP PF05086.12 EGB09021.1 - 6.9 4.5 6.2 12 3.8 6.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ank_4 PF13637.6 EGB09022.1 - 3.4e-08 33.9 0.1 6.6e-05 23.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB09022.1 - 5.3e-08 33.0 0.1 0.00018 21.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB09022.1 - 5.7e-08 33.2 0.0 2.4e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09022.1 - 1.3e-07 31.3 0.1 9e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EGB09022.1 - 1.7e-06 28.2 0.4 0.046 14.2 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeat C2 PF00168.30 EGB09023.1 - 1.7e-25 89.3 0.0 2.5e-12 47.0 0.0 3.5 3 0 0 3 3 3 3 C2 domain Hydrolase_4 PF12146.8 EGB09023.1 - 0.00048 19.5 0.1 0.001 18.4 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SRP-alpha_N PF04086.13 EGB09023.1 - 0.028 14.3 0.8 0.066 13.1 0.8 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal EF-hand_1 PF00036.32 EGB09023.1 - 0.043 13.4 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EGB09023.1 - 0.1 12.6 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EGB09023.1 - 0.16 12.4 0.2 0.37 11.3 0.2 1.6 1 0 0 1 1 1 0 EF-hand domain pair Pro_isomerase PF00160.21 EGB09024.1 - 4.1e-30 105.1 0.0 4.5e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aminotran_1_2 PF00155.21 EGB09025.1 - 1.2e-54 185.9 0.0 1.4e-54 185.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGB09025.1 - 6.8e-06 24.9 0.2 1.5e-05 23.7 0.2 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGB09025.1 - 0.00021 20.7 0.2 0.0004 19.8 0.2 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 EGB09025.1 - 0.00065 18.5 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 EGB09025.1 - 0.00073 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGB09025.1 - 0.11 11.8 4.3 0.43 9.8 4.3 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Epimerase PF01370.21 EGB09026.1 - 2.1e-07 30.6 0.0 3.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB09026.1 - 3.5e-05 23.3 0.0 0.0003 20.3 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGB09026.1 - 0.093 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 EGB09026.1 - 0.22 10.5 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Chal_sti_synt_C PF02797.15 EGB09027.1 - 6.1e-27 94.5 0.2 2.4e-26 92.6 0.0 2.0 3 0 0 3 3 3 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EGB09027.1 - 4.1e-19 68.9 0.1 5.3e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 EGB09027.1 - 5.6e-11 42.3 0.0 7.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EGB09027.1 - 4.2e-07 30.0 0.0 9.5e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGB09027.1 - 6.4e-06 25.9 1.2 1.3e-05 25.0 1.2 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LRR_8 PF13855.6 EGB09028.1 - 3.5e-19 68.3 3.2 6e-06 25.9 0.0 5.7 2 2 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EGB09028.1 - 2.9e-15 56.1 0.0 0.0087 16.5 0.0 6.0 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB09028.1 - 6.6e-05 22.6 0.4 33 4.9 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 EGB09028.1 - 0.00096 19.4 5.1 24 6.0 0.0 6.9 5 2 0 5 5 5 1 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 EGB09028.1 - 0.062 13.4 0.0 7.3 6.7 0.0 3.8 3 1 1 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain Abhydrolase_1 PF00561.20 EGB09029.1 - 4.8e-24 85.4 0.0 7.2e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB09029.1 - 1.1e-10 41.2 0.0 1.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGB09029.1 - 2.2e-07 31.7 1.4 3.1e-07 31.2 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EGB09029.1 - 0.0006 19.5 0.0 0.00085 19.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 EGB09029.1 - 0.074 12.8 0.0 7 6.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Acetyltransf_10 PF13673.7 EGB09030.1 - 1.6e-09 37.8 0.1 1.6e-09 37.7 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB09030.1 - 2.4e-06 27.9 0.2 2.8e-06 27.7 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGB09030.1 - 2.3e-05 24.6 0.1 2.6e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGB09030.1 - 0.0025 17.8 0.0 0.0027 17.7 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGB09030.1 - 0.046 13.8 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGB09030.1 - 0.061 13.5 0.1 0.19 11.9 0.1 1.8 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Myb_DNA-binding PF00249.31 EGB09031.1 - 5.3e-06 26.5 0.4 5.5e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGB09031.1 - 0.0079 16.6 3.8 0.01 16.2 0.8 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Cu_bind_like PF02298.17 EGB09033.1 - 0.0023 17.9 0.1 0.076 13.0 0.0 2.6 2 0 0 2 2 2 1 Plastocyanin-like domain MGC-24 PF05283.11 EGB09033.1 - 4.3 7.8 0.0 4.3 7.8 0.0 5.4 3 1 1 4 4 4 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CDC50 PF03381.15 EGB09034.1 - 1.4e-66 224.9 0.0 2.4e-66 224.1 0.0 1.4 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family WAK PF08488.11 EGB09034.1 - 0.082 13.4 0.0 0.27 11.8 0.0 1.8 2 0 0 2 2 2 0 Wall-associated kinase PMP1_2 PF08114.11 EGB09034.1 - 5.9 6.7 9.2 4.8 7.0 3.0 2.3 2 0 0 2 2 2 0 ATPase proteolipid family Sulfotransfer_2 PF03567.14 EGB09035.1 - 2.1e-07 31.1 0.0 2.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase family AAA PF00004.29 EGB09036.1 - 1.8e-40 138.5 0.1 8.7e-37 126.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB09036.1 - 1.8e-09 37.2 0.2 4.2e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGB09036.1 - 1.9e-06 28.4 0.0 0.0068 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 EGB09036.1 - 8.2e-06 25.3 0.0 0.082 12.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 EGB09036.1 - 0.00018 21.6 0.0 0.0041 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB09036.1 - 0.00019 21.7 0.1 0.0049 17.1 0.0 2.7 2 1 1 3 3 3 1 AAA domain TsaE PF02367.17 EGB09036.1 - 0.00045 20.2 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EGB09036.1 - 0.00058 19.6 0.0 0.087 12.6 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGB09036.1 - 0.00073 19.7 0.0 0.0025 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGB09036.1 - 0.0011 18.3 0.3 0.0028 17.1 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_N PF02359.18 EGB09036.1 - 0.0015 18.7 0.0 0.03 14.5 0.0 2.5 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activat PF00158.26 EGB09036.1 - 0.0016 18.2 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.6 EGB09036.1 - 0.0067 16.6 0.0 0.27 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGB09036.1 - 0.0082 15.7 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGB09036.1 - 0.0092 15.7 0.0 0.05 13.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 EGB09036.1 - 0.012 14.9 0.2 0.057 12.8 0.1 1.9 2 0 0 2 2 2 0 KaiC TniB PF05621.11 EGB09036.1 - 0.015 14.7 0.0 2.8 7.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein ABC_tran PF00005.27 EGB09036.1 - 0.026 15.0 0.0 0.051 14.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EGB09036.1 - 0.042 14.2 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase CDC48_2 PF02933.17 EGB09036.1 - 0.05 13.4 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 AAA_3 PF07726.11 EGB09036.1 - 0.052 13.4 0.0 0.99 9.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGB09036.1 - 0.07 13.7 0.0 0.92 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGB09036.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_24 PF13479.6 EGB09036.1 - 0.099 12.4 0.1 0.26 11.0 0.0 1.7 2 1 0 2 2 1 0 AAA domain PhoH PF02562.16 EGB09036.1 - 0.11 12.0 0.2 5 6.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 EGB09036.1 - 0.11 12.7 0.0 0.68 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGB09036.1 - 0.14 11.5 0.0 13 5.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EGB09036.1 - 0.17 11.0 0.1 0.84 8.8 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EGB09036.1 - 0.2 11.2 2.0 3.4 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ras PF00071.22 EGB09037.1 - 1.1e-56 190.9 0.0 1.3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB09037.1 - 7.4e-22 77.8 0.0 1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB09037.1 - 7.3e-08 32.1 0.0 9.3e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGB09037.1 - 0.0026 17.3 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SNARE PF05739.19 EGB09038.1 - 6.4e-08 32.5 0.1 1.2e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 SNARE domain GvpK PF05121.12 EGB09038.1 - 0.016 15.2 0.5 0.016 15.2 0.5 1.5 2 0 0 2 2 2 0 Gas vesicle protein K Syntaxin PF00804.25 EGB09038.1 - 0.06 13.0 0.4 0.94 9.1 0.0 2.0 2 0 0 2 2 2 0 Syntaxin Kinesin PF00225.23 EGB09039.1 - 2.3e-79 266.7 0.0 2.7e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB09039.1 - 6.1e-12 45.7 0.0 2.3e-11 43.8 0.0 1.9 2 1 0 2 2 2 1 Microtubule binding EF-hand_6 PF13405.6 EGB09040.1 - 7.3e-17 59.8 0.5 0.0088 15.9 0.0 6.6 7 0 0 7 7 7 4 EF-hand domain EF-hand_1 PF00036.32 EGB09040.1 - 2.3e-16 58.0 0.0 0.0052 16.2 0.0 6.7 7 0 0 7 7 7 3 EF hand EF-hand_7 PF13499.6 EGB09040.1 - 1.9e-15 57.1 0.0 3.8e-05 24.1 0.0 5.0 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB09040.1 - 8.4e-13 47.2 1.6 0.00094 18.6 0.0 5.6 7 0 0 7 7 7 3 EF hand DUF1325 PF07039.11 EGB09040.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain EF-hand_8 PF13833.6 EGB09040.1 - 0.0041 16.9 0.6 1.1 9.1 0.0 4.6 5 1 1 6 6 6 1 EF-hand domain pair CarboxypepD_reg PF13620.6 EGB09040.1 - 0.21 11.9 73.5 2 8.7 0.7 20.3 22 1 0 22 22 22 0 Carboxypeptidase regulatory-like domain TUDOR_5 PF18359.1 EGB09040.1 - 3.8 7.3 6.4 0.38 10.5 1.2 2.1 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 PMSR PF01625.21 EGB09042.1 - 9e-24 84.4 0.0 1.5e-23 83.7 0.0 1.3 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase WD40 PF00400.32 EGB09043.1 - 2.2e-27 94.8 9.7 1.1e-07 32.3 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09043.1 - 1.6e-06 28.3 0.0 0.0018 18.5 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DSPc PF00782.20 EGB09044.1 - 2.8e-15 56.3 0.0 3.3e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGB09044.1 - 0.0086 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGB09044.1 - 0.071 12.7 0.0 0.076 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGB09044.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 EGB09044.1 - 0.19 12.0 0.1 3.3 8.0 0.1 2.0 1 1 0 1 1 1 0 Rit1 DUSP-like domain EF-hand_1 PF00036.32 EGB09045.1 - 3.3e-42 138.9 8.4 2.3e-05 23.6 0.0 8.1 8 0 0 8 8 8 7 EF hand EF-hand_6 PF13405.6 EGB09045.1 - 1.7e-40 133.5 8.5 2.4e-05 23.9 0.1 8.4 8 0 0 8 8 8 7 EF-hand domain EF-hand_7 PF13499.6 EGB09045.1 - 5.3e-35 119.7 0.1 2.8e-08 34.1 0.0 6.0 6 0 0 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 EGB09045.1 - 8.8e-33 110.4 9.2 0.00015 21.1 0.1 7.4 7 0 0 7 7 7 7 EF hand EF-hand_8 PF13833.6 EGB09045.1 - 8.4e-26 89.6 6.3 1.8e-05 24.5 0.0 8.1 6 2 2 8 8 8 7 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB09045.1 - 2.5e-05 24.6 0.0 0.031 14.6 0.0 4.2 5 0 0 5 5 5 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGB09045.1 - 0.00099 20.0 0.0 54 4.7 0.0 4.6 4 1 1 5 5 4 0 EF-hand domain EF-hand_14 PF17959.1 EGB09045.1 - 0.0025 18.1 0.0 8.3 6.8 0.0 4.5 5 0 0 5 5 5 1 EF-hand domain EF-hand_4 PF12763.7 EGB09045.1 - 0.0036 17.2 0.4 15 5.6 0.0 4.7 5 1 1 6 6 6 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EGB09045.1 - 0.0093 15.9 0.5 19 5.2 0.0 4.6 6 0 0 6 6 6 0 Caleosin related protein EF-hand_9 PF14658.6 EGB09045.1 - 0.054 13.8 0.0 11 6.5 0.0 4.0 5 1 1 6 6 6 0 EF-hand domain Sad1_UNC PF07738.13 EGB09046.1 - 2.4e-29 102.0 0.0 4.3e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Prefoldin_2 PF01920.20 EGB09046.1 - 0.72 9.8 3.5 9.3 6.3 0.4 2.5 2 0 0 2 2 2 0 Prefoldin subunit Glyoxalase_4 PF13669.6 EGB09047.1 - 4.9e-14 52.5 0.0 6.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGB09047.1 - 0.0091 16.1 0.0 0.019 15.1 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain Sigma70_r2 PF04542.14 EGB09048.1 - 4.4e-20 71.2 0.1 9.6e-20 70.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EGB09048.1 - 3.4e-17 61.7 0.6 7.8e-17 60.5 0.6 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 EGB09048.1 - 1e-07 31.9 0.2 1.5e-05 24.9 0.0 3.3 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 EGB09048.1 - 3.5e-05 23.7 0.1 7.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Glyco_hydro_16 PF00722.21 EGB09051.1 - 0.0065 16.0 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Histone_H2A_C PF16211.5 EGB09053.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 C-terminus of histone H2A TerC PF03741.16 EGB09054.1 - 1.1e-47 162.0 6.4 2e-47 161.2 6.4 1.4 1 0 0 1 1 1 1 Integral membrane protein TerC family Rotamase PF00639.21 EGB09055.1 - 2.6e-16 60.3 0.0 3e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGB09055.1 - 2.3e-13 50.7 0.0 2.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EGB09055.1 - 0.0022 18.8 0.0 0.0025 18.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain P21-Arc PF04062.14 EGB09056.1 - 4.2e-61 206.0 0.0 4.7e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ANAPC5 PF12862.7 EGB09058.1 - 4.4e-23 81.2 0.3 2e-22 79.0 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 LRR_8 PF13855.6 EGB09058.1 - 6.6e-16 57.8 4.0 1.7e-05 24.5 0.2 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGB09058.1 - 8.6e-16 57.8 8.9 7e-05 23.1 0.1 5.4 2 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB09058.1 - 0.066 13.8 2.3 1.1e+02 4.0 0.1 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EGB09058.1 - 8.6 6.7 6.6 27 5.1 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich repeat IFT20 PF14931.6 EGB09059.1 - 3.5e-40 136.9 3.0 3.9e-40 136.7 3.0 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 AdoMet_Synthase PF01941.19 EGB09059.1 - 0.021 13.6 0.1 0.023 13.5 0.1 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Pox_F11 PF04943.12 EGB09059.1 - 0.081 12.0 0.8 0.083 12.0 0.8 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein Sulfotransfer_1 PF00685.27 EGB09060.1 - 7.3e-09 35.5 0.2 4.3e-07 29.7 0.1 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB09060.1 - 1.2e-07 32.4 1.7 6.7e-06 26.6 1.1 2.4 2 0 0 2 2 2 2 Sulfotransferase family SSF PF00474.17 EGB09061.1 - 3.5e-09 36.0 2.3 6.2e-09 35.2 2.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Oxidored_q4 PF00507.19 EGB09061.1 - 0.073 13.2 1.0 0.17 12.0 0.3 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF4131 PF13567.6 EGB09061.1 - 0.57 9.8 14.1 7.1 6.2 0.8 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) ketoacyl-synt PF00109.26 EGB09062.1 - 2.7e-12 46.8 8.1 2.4e-09 37.1 5.4 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGB09062.1 - 2.2e-06 27.4 7.7 2.8e-05 23.9 3.5 3.0 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ABC1 PF03109.16 EGB09063.1 - 3.8e-27 94.8 0.0 6.8e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB09063.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGB09063.1 - 0.00015 21.3 0.0 0.017 14.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain IF-2B PF01008.17 EGB09064.1 - 7.9e-63 212.3 0.0 9.5e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PhyH PF05721.13 EGB09065.1 - 6.1e-12 46.3 0.1 1.7e-11 44.8 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ank_2 PF12796.7 EGB09065.1 - 0.00046 20.7 1.6 4.8 7.8 0.0 3.9 2 1 2 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB09065.1 - 0.00084 19.9 4.7 4.4 8.0 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB09065.1 - 0.0016 18.7 5.3 0.049 14.0 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB09065.1 - 0.29 11.7 3.6 13 6.5 0.1 3.8 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 EGB09065.1 - 0.29 11.8 11.9 8.5 7.3 0.0 5.1 5 0 0 5 5 5 0 Ankyrin repeat GlcNAc PF11397.8 EGB09066.1 - 1.6e-62 212.0 12.5 8e-53 180.1 0.3 3.1 2 1 1 3 3 3 2 Glycosyltransferase (GlcNAc) Transglut_core2 PF13369.6 EGB09066.1 - 5.2e-16 58.6 0.0 1.5e-15 57.1 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily TRAM_LAG1_CLN8 PF03798.16 EGB09066.1 - 0.0001 22.1 2.6 0.00015 21.5 2.6 1.2 1 0 0 1 1 1 1 TLC domain F-box-like PF12937.7 EGB09066.1 - 0.0085 16.0 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Latrophilin PF02354.16 EGB09066.1 - 0.058 12.5 7.5 0.087 11.9 7.5 1.2 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region TFIIA PF03153.13 EGB09066.1 - 3.3 7.6 9.0 4.8 7.1 9.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Stc1 PF12898.7 EGB09067.1 - 0.0058 17.2 4.9 0.0058 17.2 4.9 1.6 2 0 0 2 2 2 1 Stc1 domain UPF0167 PF03691.14 EGB09067.1 - 0.26 11.1 2.4 0.69 9.7 0.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) Myb_DNA-binding PF00249.31 EGB09068.1 - 1.3e-09 38.1 4.3 8.7e-07 29.0 0.3 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB09068.1 - 1.7e-06 28.1 0.5 1.7e-06 28.1 0.5 2.4 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB09068.1 - 0.077 12.9 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Myb DNA-binding like DUF1840 PF08895.11 EGB09068.1 - 4.8 7.6 11.0 15 6.0 0.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) mRNA_cap_enzyme PF01331.19 EGB09069.1 - 4.4e-15 56.0 0.0 6.3e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain WW PF00397.26 EGB09069.1 - 4.8e-06 26.6 8.9 9.6e-06 25.6 8.9 1.5 1 0 0 1 1 1 1 WW domain mRNA_triPase PF02940.15 EGB09069.1 - 0.014 15.2 0.0 0.099 12.4 0.0 2.4 1 1 0 1 1 1 0 mRNA capping enzyme, beta chain mRNA_cap_C PF03919.15 EGB09069.1 - 0.044 14.4 0.0 0.085 13.5 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain DUF460 PF04312.13 EGB09069.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF460) PseudoU_synth_2 PF00849.22 EGB09070.1 - 1.7e-26 93.2 0.0 2.7e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase TGS PF02824.21 EGB09070.1 - 0.019 15.0 0.7 2.3 8.3 0.4 2.5 2 0 0 2 2 2 0 TGS domain Response_reg PF00072.24 EGB09071.1 - 5.6e-21 74.8 0.0 1.1e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGB09071.1 - 8.2e-09 36.0 0.0 2.1e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGB09071.1 - 6.3e-06 26.1 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain EGF_MSP1_1 PF12946.7 EGB09071.1 - 0.012 15.6 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 HEAT_2 PF13646.6 EGB09074.1 - 8.7e-09 35.7 4.7 1.2e-05 25.6 0.4 4.0 1 1 3 4 4 4 2 HEAT repeats HEAT PF02985.22 EGB09074.1 - 4.1e-07 29.7 4.9 0.00078 19.5 0.1 4.9 5 0 0 5 5 5 1 HEAT repeat Pkinase PF00069.25 EGB09074.1 - 1.6e-05 24.4 0.0 0.00011 21.6 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Adaptin_N PF01602.20 EGB09074.1 - 0.13 10.8 2.1 0.28 9.7 0.1 1.9 1 1 1 2 2 2 0 Adaptin N terminal region RTP1_C1 PF10363.9 EGB09074.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGB09074.1 - 0.33 11.5 14.1 0.44 11.1 0.1 5.1 5 1 1 6 6 6 0 HEAT-like repeat Aminotran_5 PF00266.19 EGB09076.1 - 4.8e-52 177.1 0.0 5.9e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Bactofilin PF04519.13 EGB09076.1 - 3.6e-18 65.7 1.2 5.7e-18 65.0 1.2 1.3 1 0 0 1 1 1 1 Polymer-forming cytoskeletal Aminotran_1_2 PF00155.21 EGB09076.1 - 0.00067 18.9 0.0 0.0063 15.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Actin PF00022.19 EGB09077.1 - 2.9e-77 260.0 0.0 9e-45 153.0 0.0 2.2 1 1 1 2 2 2 2 Actin FtsA PF14450.6 EGB09077.1 - 0.0047 17.3 0.0 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 Cell division protein FtsA Ion_trans_2 PF07885.16 EGB09078.1 - 4.4e-23 81.1 18.0 2.2e-12 46.7 6.5 2.5 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 EGB09078.1 - 0.00015 21.1 4.5 0.0057 15.9 0.1 2.4 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 EGB09078.1 - 0.071 12.9 0.8 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF4083 PF13314.6 EGB09078.1 - 0.46 10.5 1.1 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) ABC_tran PF00005.27 EGB09079.1 - 7e-17 62.2 0.0 2.7e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 EGB09079.1 - 0.01 15.4 0.2 0.012 15.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB09079.1 - 0.053 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EGB09079.1 - 0.11 12.2 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB09080.1 - 8.4e-27 94.4 0.0 1.1e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGB09080.1 - 0.0013 18.2 0.6 0.043 13.2 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EGB09080.1 - 0.0015 18.6 0.1 0.0027 17.8 0.1 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 EGB09080.1 - 0.022 14.8 0.6 0.063 13.4 0.6 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB09080.1 - 0.037 14.4 1.0 0.066 13.6 1.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 EGB09080.1 - 0.066 13.0 0.0 7.5 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB09080.1 - 0.11 12.2 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Amidohydro_2 PF04909.14 EGB09082.1 - 5.2e-21 75.7 1.3 1e-20 74.8 1.3 1.5 1 0 0 1 1 1 1 Amidohydrolase Evr1_Alr PF04777.13 EGB09082.1 - 0.0031 17.9 0.1 0.16 12.4 0.4 2.9 2 1 0 2 2 2 1 Erv1 / Alr family Ras PF00071.22 EGB09083.1 - 1e-39 135.7 0.0 1.3e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB09083.1 - 1.8e-27 95.9 0.0 2.6e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB09083.1 - 1.9e-11 43.7 0.0 1.1e-10 41.2 0.0 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB09083.1 - 4.7e-07 29.9 0.0 9.1e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB09083.1 - 3.2e-05 23.5 0.0 0.0008 19.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGB09083.1 - 0.0065 15.9 0.0 0.0083 15.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGB09083.1 - 0.018 14.9 0.0 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EGB09083.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGB09083.1 - 0.14 11.7 0.0 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.6 EGB09083.1 - 0.2 11.7 0.0 4.5 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain LRR_6 PF13516.6 EGB09084.1 - 1.3e-10 40.4 0.0 0.58 10.3 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 EGB09084.1 - 8.9e-06 26.0 0.0 1.4 9.4 0.0 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB09084.1 - 2.7e-05 23.8 0.1 1 9.2 0.0 3.7 2 2 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 EGB09084.1 - 0.00043 20.4 0.0 27 5.8 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat PBP1_TM PF14812.6 EGB09084.1 - 0.16 12.3 12.1 1.3 9.5 0.9 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_polI_A34 PF08208.11 EGB09084.1 - 0.21 11.6 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SBF_like PF13593.6 EGB09085.1 - 6.3e-74 249.1 16.0 7.1e-74 248.9 16.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EGB09085.1 - 7.1e-11 42.2 3.5 7.1e-11 42.2 3.5 2.0 1 1 1 2 2 2 1 Sodium Bile acid symporter family YjbE PF11106.8 EGB09085.1 - 0.056 13.7 0.8 0.056 13.7 0.8 3.0 3 1 0 3 3 3 0 Exopolysaccharide production protein YjbE cNMP_binding PF00027.29 EGB09086.1 - 2e-27 95.1 0.1 8.9e-17 61.0 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGB09087.1 - 1.3e-57 195.1 0.0 1.7e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09087.1 - 1.1e-33 116.6 0.0 1.3e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09087.1 - 0.00036 19.9 0.0 0.00073 18.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB09087.1 - 0.00081 19.4 0.0 0.0023 17.9 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB09087.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Ank_2 PF12796.7 EGB09088.1 - 5.8e-05 23.6 0.1 0.00015 22.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) YrhK PF14145.6 EGB09089.1 - 0.017 15.0 2.2 0.038 13.9 2.2 1.5 1 0 0 1 1 1 0 YrhK-like protein PHO4 PF01384.20 EGB09089.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 1 0 1 1 1 0 Phosphate transporter family ABC2_membrane_3 PF12698.7 EGB09089.1 - 0.11 11.6 1.5 0.14 11.3 1.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein EF-hand_1 PF00036.32 EGB09090.1 - 3.8e-29 98.0 3.1 3e-07 29.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB09090.1 - 8.6e-29 99.8 2.4 2.8e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB09090.1 - 3.3e-24 82.7 5.1 3e-07 29.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB09090.1 - 1.5e-22 79.2 8.7 2.4e-12 46.5 0.0 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB09090.1 - 4.7e-18 63.8 9.3 0.00015 21.1 0.1 4.5 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 EGB09090.1 - 1.1e-05 25.6 0.2 0.036 14.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 EGB09090.1 - 4.6e-05 23.7 0.3 0.0077 16.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB09090.1 - 0.00023 21.5 0.1 0.0081 16.5 0.0 2.6 2 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGB09090.1 - 0.0056 16.5 0.8 0.47 10.4 0.3 2.4 2 0 0 2 2 2 1 EF hand DUF5640 PF18692.1 EGB09090.1 - 0.066 13.3 0.5 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5640) DUF1456 PF07308.13 EGB09090.1 - 0.076 13.4 0.4 10 6.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Nuc_sug_transp PF04142.15 EGB09091.1 - 4e-24 85.3 11.3 5e-24 85.0 11.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB09091.1 - 9e-10 38.9 17.4 7.1e-06 26.2 0.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EGB09091.1 - 0.00014 21.2 1.2 0.00014 21.2 1.2 2.4 2 1 0 3 3 3 1 Purine nucleobase transmembrane transport TPT PF03151.16 EGB09091.1 - 0.0018 17.7 0.4 0.0018 17.7 0.4 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 EGB09091.1 - 0.0019 17.5 16.1 0.0032 16.7 16.0 1.4 1 1 0 1 1 1 1 UAA transporter family Pkinase PF00069.25 EGB09092.1 - 4.3e-29 101.7 0.0 4.7e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09092.1 - 4.3e-19 68.8 0.0 4.6e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB09092.1 - 1.4e-05 24.1 0.0 1.6e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB09092.1 - 0.00092 18.6 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleotid_trans PF03407.16 EGB09093.1 - 0.0058 16.6 0.0 0.0074 16.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase GFA PF04828.14 EGB09094.1 - 8.2e-14 51.7 0.6 1.2e-13 51.2 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S15 PF00312.22 EGB09095.1 - 4.1e-21 75.0 0.2 4.5e-21 74.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 Ank_4 PF13637.6 EGB09096.1 - 0.0034 17.9 0.0 0.01 16.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB09096.1 - 0.0041 17.7 0.0 0.0087 16.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09096.1 - 0.024 15.1 0.0 0.08 13.5 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 EGB09096.1 - 0.095 13.2 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat PMSR PF01625.21 EGB09097.1 - 3.5e-34 118.2 4.8 6.9e-34 117.2 4.8 1.4 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase GLF PF03275.13 EGB09098.1 - 1.7e-70 236.9 0.0 1.9e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 UDP-galactopyranose mutase RhoGEF PF00621.20 EGB09099.1 - 1.7e-38 132.7 0.0 3e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Ion_trans PF00520.31 EGB09099.1 - 1.4e-12 47.4 22.2 2.2e-06 27.1 12.3 2.3 2 0 0 2 2 2 2 Ion transport protein PH PF00169.29 EGB09099.1 - 2.9e-09 37.4 0.0 0.00049 20.6 0.0 2.5 2 0 0 2 2 2 2 PH domain zf-C3HC4_2 PF13923.6 EGB09099.1 - 1e-08 34.8 3.5 2.2e-08 33.8 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB09099.1 - 3.4e-07 30.2 4.6 7.1e-07 29.1 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGB09099.1 - 4.2e-07 29.7 3.4 8.9e-07 28.7 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB09099.1 - 4.3e-07 30.1 3.7 1.1e-06 28.8 3.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGB09099.1 - 1.8e-06 27.8 3.2 4.3e-06 26.6 3.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.21 EGB09099.1 - 2.5e-06 27.5 7.3 2.5e-06 27.5 7.3 2.6 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 EGB09099.1 - 7.2e-06 25.8 3.5 2e-05 24.4 3.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 EGB09099.1 - 0.00096 19.7 0.1 0.0023 18.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-rbx1 PF12678.7 EGB09099.1 - 0.0019 18.4 0.8 0.0046 17.2 0.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain ANAPC4_WD40 PF12894.7 EGB09099.1 - 0.0028 17.9 0.0 0.78 10.1 0.0 4.2 4 1 0 4 4 3 1 Anaphase-promoting complex subunit 4 WD40 domain Prok-RING_4 PF14447.6 EGB09099.1 - 0.0066 16.3 4.3 0.014 15.2 4.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank_5 PF13857.6 EGB09099.1 - 0.0077 16.5 0.1 7 7.1 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) WD40 PF00400.32 EGB09099.1 - 0.014 16.2 9.5 40 5.3 0.1 6.7 7 0 0 7 7 6 0 WD domain, G-beta repeat GYF_2 PF14237.6 EGB09099.1 - 0.025 14.4 0.1 0.073 12.9 0.1 1.9 1 0 0 1 1 1 0 GYF domain 2 zf-C3HC4_4 PF15227.6 EGB09099.1 - 0.044 13.9 4.2 0.11 12.7 4.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PKD_channel PF08016.12 EGB09099.1 - 0.055 12.1 9.1 0.1 11.2 9.1 1.5 1 0 0 1 1 1 0 Polycystin cation channel EF-hand_5 PF13202.6 EGB09099.1 - 0.065 12.8 0.1 0.22 11.1 0.1 1.8 1 0 0 1 1 1 0 EF hand zf-RING_11 PF17123.5 EGB09099.1 - 0.073 12.8 3.6 0.16 11.7 3.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Ank_3 PF13606.6 EGB09099.1 - 0.075 13.6 0.0 46 5.0 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat EF-hand_7 PF13499.6 EGB09099.1 - 0.079 13.4 2.0 0.31 11.5 2.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair Laminin_II PF06009.12 EGB09099.1 - 0.14 12.2 1.0 0.68 9.9 0.2 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF3584 PF12128.8 EGB09099.1 - 0.19 9.2 29.9 0.33 8.4 29.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-Nse PF11789.8 EGB09099.1 - 0.23 11.3 0.5 0.48 10.3 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 EGB09099.1 - 0.78 9.9 3.9 1.8 8.7 3.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Methyltransf_25 PF13649.6 EGB09100.1 - 1.7e-19 70.3 3.4 1.4e-11 44.9 0.5 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09100.1 - 1e-16 61.3 3.7 1.7e-10 41.4 0.3 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGB09100.1 - 1.1e-14 54.9 0.3 1.6e-09 38.4 0.1 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09100.1 - 1.1e-13 51.3 0.0 7.6e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGB09100.1 - 5.7e-12 45.7 0.3 5.5e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain DOT1 PF08123.13 EGB09100.1 - 1.2e-08 34.8 0.5 1.3e-05 24.8 0.1 2.4 3 0 0 3 3 3 2 Histone methylation protein DOT1 TPMT PF05724.11 EGB09100.1 - 5e-07 29.6 0.1 4.2e-06 26.6 0.0 2.3 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 EGB09100.1 - 9e-06 25.3 1.0 0.023 14.3 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase small domain PCMT PF01135.19 EGB09100.1 - 2.9e-05 23.9 0.0 0.0047 16.7 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGB09100.1 - 0.00015 21.8 0.3 0.075 13.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MetW PF07021.12 EGB09100.1 - 0.00035 20.2 0.1 0.25 10.9 0.0 2.6 3 0 0 3 3 3 2 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 EGB09100.1 - 0.00087 18.8 0.2 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.11 EGB09100.1 - 0.0044 16.7 0.1 0.031 13.9 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 EGB09100.1 - 0.011 15.3 0.2 1 8.9 0.0 2.1 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase CMAS PF02353.20 EGB09100.1 - 0.013 14.8 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGB09100.1 - 0.028 13.8 0.4 0.061 12.7 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGB09100.1 - 1.3 8.3 4.7 1.2 8.4 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_14 PF13428.6 EGB09101.1 - 8.3e-11 41.8 75.3 0.012 16.4 0.1 13.7 7 2 7 14 14 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09101.1 - 3.9e-09 36.0 17.8 0.00053 20.0 0.0 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat Suf PF05843.14 EGB09101.1 - 1.5e-08 35.0 0.0 2.9 7.8 0.0 5.0 5 1 0 5 5 5 3 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 EGB09101.1 - 5.1e-07 29.1 1.0 0.087 11.9 0.0 4.4 3 1 1 4 4 4 3 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 EGB09101.1 - 5.2e-07 29.7 0.7 0.18 11.8 0.1 5.3 5 0 0 5 5 5 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGB09101.1 - 6.1e-05 22.8 42.1 0.00017 21.4 0.1 9.8 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09101.1 - 0.00027 20.6 12.8 0.017 15.0 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 EGB09101.1 - 0.0028 17.4 0.5 0.33 10.7 0.0 3.1 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 EGB09101.1 - 0.0075 16.2 0.1 0.0075 16.2 0.1 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat SNAP PF14938.6 EGB09101.1 - 0.013 15.0 11.7 1.3 8.4 4.0 3.5 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 EGB09101.1 - 0.04 14.6 0.1 0.035 14.8 12.7 9.4 7 1 2 9 9 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09101.1 - 0.077 13.3 0.0 0.077 13.3 0.0 6.7 7 2 2 9 9 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09101.1 - 0.27 11.8 35.6 12 6.5 0.0 8.3 7 1 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB09101.1 - 0.29 10.8 13.5 8 6.2 0.1 6.6 7 0 0 7 7 7 0 TPR repeat TPR_4 PF07721.14 EGB09101.1 - 0.49 11.2 0.0 0.49 11.2 0.0 9.5 11 0 0 11 11 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB09101.1 - 0.71 9.8 0.0 0.71 9.8 0.0 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat COesterase PF00135.28 EGB09102.1 - 8.1e-45 153.6 1.4 9e-45 153.5 1.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGB09102.1 - 1.1e-11 45.1 2.9 3.1e-05 24.0 0.5 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold SpoU_methylase PF00588.19 EGB09103.1 - 3.3e-26 92.1 0.0 3.8e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family MMR_HSR1 PF01926.23 EGB09104.1 - 1.8e-14 53.8 0.0 5.6e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB09104.1 - 1.5e-06 27.9 0.0 0.00023 20.7 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGB09104.1 - 0.00013 21.9 0.1 0.047 13.6 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EGB09104.1 - 0.00085 19.4 1.2 2.4 8.2 0.3 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EGB09104.1 - 0.00089 18.8 0.1 0.077 12.5 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EGB09104.1 - 0.023 14.3 0.2 3.4 7.2 0.0 2.6 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGB09104.1 - 0.064 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 EGB09104.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGB09104.1 - 0.079 13.3 1.3 0.24 11.8 0.4 2.2 2 1 0 2 2 2 0 AAA ATPase domain Solute_trans_a PF03619.16 EGB09105.1 - 6.5e-83 278.3 10.3 7.3e-83 278.1 10.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DLIC PF05783.11 EGB09106.1 - 1.1e-07 31.1 0.0 2.6e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 EGB09106.1 - 5.1e-05 23.5 0.0 0.00052 20.2 0.0 2.5 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGB09106.1 - 0.01 15.7 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EGB09106.1 - 0.01 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EGB09106.1 - 0.042 14.2 0.2 0.21 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGB09106.1 - 0.058 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 EGB09106.1 - 0.12 12.0 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Ras family MMR_HSR1 PF01926.23 EGB09106.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Alg14 PF08660.11 EGB09108.1 - 1.7e-53 181.1 0.0 2.3e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Peptidase_M20 PF01546.28 EGB09109.1 - 2e-22 79.9 1.6 3.3e-22 79.2 1.6 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGB09109.1 - 3.8e-12 46.1 0.1 3.8e-12 46.1 0.1 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain NHase_alpha PF02979.16 EGB09110.1 - 4.5e-71 238.0 0.0 5.1e-71 237.8 0.0 1.0 1 0 0 1 1 1 1 Nitrile hydratase, alpha chain Frankia_peptide PF14407.6 EGB09110.1 - 8.5e-05 22.5 2.0 0.00074 19.5 0.2 2.4 2 0 0 2 2 2 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Amidohydro_2 PF04909.14 EGB09110.1 - 0.037 13.8 0.8 0.048 13.5 0.8 1.1 1 0 0 1 1 1 0 Amidohydrolase GGDEF_2 PF17853.1 EGB09110.1 - 0.35 11.1 4.1 1.1 9.5 4.1 1.9 1 1 0 1 1 1 0 GGDEF-like domain PCNA_N PF00705.18 EGB09111.1 - 2.6e-50 169.4 2.3 4.9e-50 168.5 2.3 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EGB09111.1 - 1.3e-46 158.0 0.0 2.1e-45 154.0 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EGB09111.1 - 5.5e-10 38.8 0.2 5.9e-09 35.4 0.2 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EGB09111.1 - 5.3e-08 32.6 0.0 6.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 EGB09111.1 - 0.00085 18.5 0.0 0.0031 16.7 0.0 1.7 1 1 0 2 2 2 1 Hus1-like protein PCC_BT PF18140.1 EGB09111.1 - 0.096 13.0 0.0 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain Myotub-related PF06602.14 EGB09112.1 - 2.4e-113 378.7 0.0 2.8e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGB09112.1 - 0.00092 19.3 0.1 0.0016 18.5 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGB09112.1 - 0.0025 17.6 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB09112.1 - 0.0026 17.4 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Spt4 PF06093.13 EGB09113.1 - 1.3e-22 79.7 0.0 1.6e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TPR_12 PF13424.6 EGB09114.1 - 1.9e-84 278.0 30.6 2.2e-17 63.1 3.0 6.3 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 EGB09114.1 - 1.8e-52 173.9 25.4 3.8e-10 39.3 0.0 9.1 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGB09114.1 - 8.6e-31 103.7 15.4 0.00085 19.2 0.0 7.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09114.1 - 3.3e-25 86.8 9.5 0.0025 17.6 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGB09114.1 - 2.1e-22 77.3 21.4 0.0016 18.4 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGB09114.1 - 2.8e-21 74.4 34.6 0.0036 18.0 0.2 7.8 5 3 3 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09114.1 - 2.5e-19 67.8 1.4 0.0015 18.6 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09114.1 - 1.9e-17 63.6 26.2 1.5e-06 28.7 5.0 6.7 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB09114.1 - 1.1e-14 54.6 8.0 8.3e-09 35.3 1.3 3.7 1 1 1 3 3 3 3 MalT-like TPR region TPR_19 PF14559.6 EGB09114.1 - 2.4e-12 47.2 13.5 0.0094 16.4 0.2 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_4 PF07721.14 EGB09114.1 - 8.7e-10 38.3 47.7 0.045 14.4 1.5 8.3 9 1 0 9 9 7 5 Tetratricopeptide repeat TPR_5 PF12688.7 EGB09114.1 - 2.4e-09 37.5 6.3 0.0013 19.0 0.3 5.1 4 1 1 5 5 5 2 Tetratrico peptide repeat TPR_17 PF13431.6 EGB09114.1 - 1.4e-06 28.2 9.6 0.31 11.5 0.0 7.0 8 3 0 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB09114.1 - 6.4e-05 23.1 0.1 9.9 6.5 0.1 4.5 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGB09114.1 - 7.7e-05 23.1 14.3 0.37 11.5 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN6_N PF18055.1 EGB09114.1 - 0.00025 21.4 0.0 0.0029 18.0 0.0 2.5 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4404 PF14357.6 EGB09114.1 - 0.0066 17.1 1.8 4.4 8.0 0.1 3.9 4 2 0 4 4 3 1 Domain of unknown function (DUF4404) SNAP PF14938.6 EGB09114.1 - 0.065 12.7 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.9 EGB09114.1 - 0.17 11.3 1.3 1.2e+02 2.2 0.0 4.4 4 0 0 4 4 4 0 SHNi-TPR TPR_11 PF13414.6 EGB09114.1 - 0.18 11.5 13.9 5.7 6.7 0.3 6.2 7 0 0 7 7 7 0 TPR repeat TPR_21 PF09976.9 EGB09114.1 - 9.2 5.9 8.3 44 3.7 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain CA_like PF10563.9 EGB09115.1 - 4.6e-57 192.9 2.5 5.8e-57 192.6 2.5 1.1 1 0 0 1 1 1 1 Putative carbonic anhydrase DUF21 PF01595.20 EGB09117.1 - 4.8e-23 81.7 2.1 5.2e-23 81.6 2.1 1.0 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Nt_Gln_amidase PF09764.9 EGB09118.1 - 5.7e-40 136.9 0.0 6.5e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase UAA PF08449.11 EGB09120.1 - 2.3e-48 165.0 0.0 2.6e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB09120.1 - 0.11 12.7 17.9 0.065 13.4 3.7 2.5 2 1 0 2 2 2 0 EamA-like transporter family EF-hand_7 PF13499.6 EGB09121.1 - 6.2e-16 58.6 0.2 4.5e-14 52.7 0.1 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB09121.1 - 0.00011 21.5 0.2 0.11 12.1 0.0 4.1 4 0 0 4 4 4 1 EF hand EF-hand_13 PF17958.1 EGB09121.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EGB09121.1 - 0.001 18.5 6.1 0.0028 17.1 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 EGB09121.1 - 0.0021 17.8 1.0 0.28 11.2 0.1 3.6 3 0 0 3 3 3 1 EF-hand domain TPT PF03151.16 EGB09122.1 - 8.7e-11 41.7 15.9 1.1e-10 41.4 15.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB09122.1 - 0.00012 22.3 6.8 0.00012 22.3 6.8 2.7 2 2 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EGB09122.1 - 0.0017 17.6 4.7 0.3 10.2 0.4 2.6 2 1 1 3 3 3 2 Nucleotide-sugar transporter Ion_trans_2 PF07885.16 EGB09123.1 - 3.1e-22 78.3 16.6 1.4e-13 50.5 4.7 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 EGB09123.1 - 1.2e-05 24.7 3.8 0.0018 17.5 0.9 2.2 2 0 0 2 2 2 2 Ion transport protein Oxidored_q3 PF00499.20 EGB09123.1 - 0.0046 16.7 0.1 0.11 12.2 0.1 2.6 2 1 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ni_hydr_CYTB PF01292.20 EGB09123.1 - 0.22 11.1 3.5 0.56 9.8 2.2 2.2 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 DUF3040 PF11239.8 EGB09123.1 - 9.8 6.5 12.2 6.5 7.1 1.6 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) Transketolase_N PF00456.21 EGB09124.1 - 3.3e-105 351.7 0.3 4.1e-105 351.4 0.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGB09124.1 - 2.4e-36 125.1 0.0 4.9e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGB09124.1 - 1.3e-12 47.6 0.0 2.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EGB09124.1 - 1.3e-07 31.1 0.1 6.3e-05 22.3 0.1 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EGB09124.1 - 0.0002 20.4 0.1 0.00032 19.8 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGB09124.1 - 0.01 15.7 0.1 0.21 11.4 0.1 2.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain cNMP_binding PF00027.29 EGB09125.1 - 4.2e-14 52.4 0.1 1.6e-13 50.5 0.1 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB09125.1 - 3.4e-08 33.0 24.3 1.4e-07 31.0 24.3 2.0 1 1 0 1 1 1 1 Ion transport protein CDC45 PF02724.14 EGB09125.1 - 0.7 8.1 2.3 1.2 7.3 2.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Lig_chan PF00060.26 EGB09125.1 - 1 9.2 2.8 11 5.8 0.1 2.7 2 0 0 2 2 2 0 Ligand-gated ion channel ASFV_L11L PF05293.11 EGB09125.1 - 3.3 8.1 7.7 0.52 10.7 2.6 2.4 2 0 0 2 2 2 0 African swine fever virus (ASFV) L11L protein MMR_HSR1 PF01926.23 EGB09126.1 - 2.1e-45 153.5 0.0 9.2e-23 80.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 EGB09126.1 - 1.3e-27 96.0 0.0 5.2e-27 94.0 0.0 2.1 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 EGB09126.1 - 2.6e-21 75.8 0.0 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGB09126.1 - 8.4e-14 51.6 2.7 3.3e-06 26.8 0.7 4.7 3 1 0 3 3 3 3 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EGB09126.1 - 5e-12 45.6 0.0 6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EGB09126.1 - 4.8e-10 39.6 0.1 0.0079 16.1 0.0 4.0 3 1 0 3 3 3 2 RsgA GTPase Roc PF08477.13 EGB09126.1 - 6.8e-09 36.0 0.0 0.009 16.2 0.0 3.4 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGB09126.1 - 1.2e-07 31.9 0.2 0.17 11.9 0.0 3.9 2 2 2 4 4 4 3 Dynamin family Ras PF00071.22 EGB09126.1 - 7.7e-07 28.8 0.5 0.0022 17.6 0.2 3.3 2 2 0 2 2 2 2 Ras family AAA_16 PF13191.6 EGB09126.1 - 9.4e-07 29.4 4.4 0.00084 19.8 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain TniB PF05621.11 EGB09126.1 - 1.8e-05 24.2 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein MCM PF00493.23 EGB09126.1 - 0.00033 19.8 0.0 0.57 9.2 0.0 2.4 2 0 0 2 2 2 2 MCM P-loop domain AAA_22 PF13401.6 EGB09126.1 - 0.00045 20.5 0.1 1.1 9.5 0.0 3.2 3 1 0 3 3 2 2 AAA domain cobW PF02492.19 EGB09126.1 - 0.00059 19.5 3.4 0.12 11.9 0.4 3.1 3 1 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EGB09126.1 - 0.0014 18.4 0.0 1.1 8.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain SRPRB PF09439.10 EGB09126.1 - 0.0032 16.9 0.0 0.34 10.3 0.0 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EGB09126.1 - 0.0032 18.0 0.0 0.27 11.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 EGB09126.1 - 0.0063 16.4 0.0 7.3 6.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.6 EGB09126.1 - 0.0091 16.3 1.5 1.8 8.8 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB09126.1 - 0.014 15.9 0.1 2.4 8.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGB09126.1 - 0.014 15.7 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EGB09126.1 - 0.021 15.2 0.1 1 9.8 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGB09126.1 - 0.046 13.7 0.1 3.6 7.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EGB09126.1 - 0.18 11.5 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AMP-binding PF00501.28 EGB09127.1 - 2.5e-37 128.5 0.1 4.4e-37 127.7 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_2 PF13360.6 EGB09127.1 - 7.9e-28 97.6 19.5 1.3e-18 67.4 5.9 3.7 2 1 2 4 4 4 3 PQQ-like domain PQQ_3 PF13570.6 EGB09127.1 - 2.6e-17 62.7 67.1 2.4e-05 24.7 0.6 10.3 10 0 0 10 10 10 6 PQQ-like domain PQQ PF01011.21 EGB09127.1 - 2.5e-16 58.7 13.9 0.00049 19.9 0.1 6.9 7 0 0 7 7 7 5 PQQ enzyme repeat cNMP_binding PF00027.29 EGB09127.1 - 6.2e-10 39.0 0.0 0.00031 20.8 0.0 3.0 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain TIR_2 PF13676.6 EGB09127.1 - 1.5e-08 35.2 0.0 3.9e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 TIR domain PP-binding PF00550.25 EGB09127.1 - 1.6e-05 25.2 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF4062 PF13271.6 EGB09127.1 - 0.00013 22.2 0.0 0.00025 21.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) Cytochrom_D1 PF02239.16 EGB09127.1 - 0.095 11.2 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EGB09127.1 - 0.13 12.6 0.0 4.8 7.6 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ABC1 PF03109.16 EGB09128.1 - 3.9e-19 69.0 0.1 1.1e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EGB09128.1 - 0.015 15.3 0.1 0.045 13.7 0.1 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family TFIID_NTD2 PF04494.15 EGB09129.1 - 2.7e-27 95.5 0.0 3.6e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 EGB09129.1 - 1.1e-25 89.4 18.7 7.5e-08 32.9 0.8 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09129.1 - 0.009 16.3 0.0 5.7 7.3 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S18 PF01084.20 EGB09130.1 - 1.2e-13 51.1 0.3 1.8e-13 50.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 OmpH PF03938.14 EGB09131.1 - 0.012 16.0 4.3 0.019 15.3 4.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EGB09131.1 - 0.47 9.8 3.0 0.73 9.1 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAPS_reduct PF01507.19 EGB09132.1 - 6.6e-26 91.4 0.0 7.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 EGB09133.1 - 2.4e-12 46.7 0.1 2.6e-12 46.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB09133.1 - 0.0046 17.4 0.7 0.015 15.8 0.7 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGB09133.1 - 0.033 14.1 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 EGB09133.1 - 0.043 14.0 0.1 0.058 13.6 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like Pkinase PF00069.25 EGB09134.1 - 2.7e-54 184.3 0.0 3.6e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PGP_phosphatase PF09419.10 EGB09134.1 - 5.2e-35 120.5 0.0 8e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Pkinase_Tyr PF07714.17 EGB09134.1 - 1.7e-25 89.8 0.0 2.4e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Cys_Met_Meta_PP PF01053.20 EGB09134.1 - 1.2e-07 30.7 0.0 2.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Hydrolase_like PF13242.6 EGB09134.1 - 6.5e-05 22.9 0.1 0.00077 19.5 0.1 2.7 2 0 0 2 2 2 1 HAD-hyrolase-like Kinase-like PF14531.6 EGB09134.1 - 0.00085 18.7 0.0 0.0081 15.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Hydrolase PF00702.26 EGB09134.1 - 0.027 14.8 0.8 0.53 10.5 0.1 2.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase ASCH PF04266.14 EGB09134.1 - 0.036 14.7 0.0 0.09 13.4 0.0 1.7 2 0 0 2 2 2 0 ASCH domain Sel1 PF08238.12 EGB09135.1 - 4.5e-27 93.9 27.7 4.2e-05 24.1 0.5 8.2 8 0 0 8 8 8 8 Sel1 repeat AAA_lid_10 PF17872.1 EGB09135.1 - 3.4e-06 27.1 1.2 0.46 10.6 0.1 3.4 3 0 0 3 3 3 3 AAA lid domain Flu_M1_C PF08289.11 EGB09135.1 - 0.00023 21.3 0.5 0.52 10.6 0.0 3.4 3 0 0 3 3 3 1 Influenza Matrix protein (M1) C-terminal domain GcnA_N PF18229.1 EGB09135.1 - 0.0027 17.7 0.0 8.8 6.4 0.0 3.5 3 1 0 3 3 3 2 N-acetyl-beta-D-glucosaminidase N-terminal domain DUF4878 PF12870.7 EGB09135.1 - 0.012 16.0 3.4 3.8 7.8 0.0 3.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4878) Fe-S_biosyn PF01521.20 EGB09135.1 - 0.012 15.8 0.0 3.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Iron-sulphur cluster biosynthesis CART PF06373.11 EGB09135.1 - 0.013 15.6 2.7 1.1 9.6 0.1 2.7 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) ABA_WDS PF02496.16 EGB09135.1 - 2 8.9 10.7 10 6.7 0.7 3.3 3 0 0 3 3 3 0 ABA/WDS induced protein Sugar_tr PF00083.24 EGB09136.1 - 8.2e-91 305.1 11.7 9.3e-91 304.9 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB09136.1 - 4.4e-23 81.8 32.9 4.4e-23 81.8 32.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EGB09136.1 - 0.024 13.0 1.2 0.052 11.8 1.2 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CS PF04969.16 EGB09138.1 - 2.4e-07 31.7 0.0 3.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 CS domain Sulfotransfer_3 PF13469.6 EGB09139.1 - 1.6e-28 100.6 0.0 6.8e-28 98.5 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family zf-Tim10_DDP PF02953.15 EGB09139.1 - 3.1e-13 49.2 6.2 6e-13 48.2 6.2 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger 2OG-FeII_Oxy_3 PF13640.6 EGB09139.1 - 4.2e-11 43.6 0.0 9.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sulfotransfer_1 PF00685.27 EGB09139.1 - 7.6e-09 35.4 0.0 5.3e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain zf-CCCH_4 PF18044.1 EGB09139.1 - 0.0079 16.0 0.3 0.018 14.9 0.3 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGB09139.1 - 0.012 15.5 0.3 0.012 15.5 0.3 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sulfotransfer_4 PF17784.1 EGB09139.1 - 0.093 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Sulfotransferase domain PX PF00787.24 EGB09140.1 - 3.6e-09 36.6 0.0 6.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 EGB09141.1 - 8.4e-38 130.2 0.0 9.3e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09141.1 - 5.2e-19 68.5 0.0 5.9e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09141.1 - 8.9e-05 21.9 0.0 9.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB09141.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB09141.1 - 0.0029 17.6 3.4 0.02 14.8 1.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB09141.1 - 0.064 12.2 0.0 0.081 11.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGB09141.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MutS_V PF00488.21 EGB09142.1 - 3.3e-73 245.7 0.0 4.3e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGB09142.1 - 0.054 13.7 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 MutS domain III AAA_27 PF13514.6 EGB09142.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGB09142.1 - 0.17 11.6 0.3 0.4 10.4 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SATase_N PF06426.14 EGB09144.1 - 5.9e-22 78.0 0.1 7.9e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 EGB09144.1 - 1.8e-11 43.3 7.5 7.5e-08 31.8 0.6 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB09144.1 - 6.4e-07 29.0 10.2 4.7e-06 26.2 1.0 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NAD_binding_10 PF13460.6 EGB09145.1 - 1.8e-36 125.8 0.3 2.7e-36 125.2 0.3 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGB09145.1 - 1e-10 41.6 2.1 6.3e-06 25.9 0.7 2.8 2 1 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 EGB09145.1 - 2.1e-07 30.7 0.1 7e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB09145.1 - 4.1e-06 26.0 0.0 0.022 13.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EGB09145.1 - 0.0035 17.6 0.2 0.0058 16.9 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.15 EGB09145.1 - 0.0067 15.6 0.0 3.2 6.8 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EGB09145.1 - 0.0072 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGB09145.1 - 0.012 15.9 0.7 0.02 15.1 0.7 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EGB09145.1 - 0.035 14.6 0.2 0.059 13.8 0.2 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EGB09145.1 - 0.059 13.5 0.2 0.091 12.9 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.25 EGB09146.1 - 5.8e-43 147.1 0.0 8.2e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 EGB09146.1 - 1.3e-34 120.0 0.0 2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 EGB09146.1 - 9.9e-21 74.2 0.0 1.4e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rhomboid PF01694.22 EGB09146.1 - 1.6e-20 73.7 8.3 2.5e-20 73.0 8.3 1.3 1 0 0 1 1 1 1 Rhomboid family PP2C_2 PF13672.6 EGB09146.1 - 1e-05 25.3 6.6 3.4e-05 23.6 6.6 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Kinase-like PF14531.6 EGB09146.1 - 3.6e-05 23.2 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SpoIIE PF07228.12 EGB09146.1 - 0.0027 17.7 6.6 0.087 12.7 0.5 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) AAA_2 PF07724.14 EGB09147.1 - 1.5e-42 145.6 0.1 1.2e-34 119.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGB09147.1 - 8.7e-14 52.1 0.2 1.3e-05 25.6 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGB09147.1 - 3.3e-08 33.6 0.2 3.8e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 EGB09147.1 - 2.7e-07 30.5 0.8 9e-07 28.9 0.2 2.2 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 EGB09147.1 - 2.5e-05 23.5 0.1 0.0017 17.5 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 EGB09147.1 - 6.1e-05 23.3 0.1 0.00054 20.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EGB09147.1 - 0.00014 22.3 5.2 0.00022 21.7 0.7 2.9 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 EGB09147.1 - 0.00015 21.2 1.7 0.0018 17.7 0.6 2.8 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGB09147.1 - 0.00093 19.7 0.1 0.0031 18.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 EGB09147.1 - 0.001 18.3 0.1 0.0022 17.3 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 EGB09147.1 - 0.0023 17.6 0.0 0.028 14.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGB09147.1 - 0.0044 16.3 0.1 0.025 13.9 0.1 2.2 1 1 1 2 2 2 1 Zeta toxin TniB PF05621.11 EGB09147.1 - 0.0067 15.9 0.3 0.28 10.6 0.0 2.6 2 1 1 3 3 3 1 Bacterial TniB protein ATP-synt_ab PF00006.25 EGB09147.1 - 0.0075 15.9 1.7 0.051 13.2 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 EGB09147.1 - 0.0096 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 EGB09147.1 - 0.0097 16.1 0.1 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EGB09147.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EGB09147.1 - 0.02 15.2 0.3 0.073 13.3 0.1 2.1 2 0 0 2 2 1 0 AAA domain SKI PF01202.22 EGB09147.1 - 0.027 14.6 0.6 1.3 9.2 0.3 3.1 2 1 0 2 2 2 0 Shikimate kinase G-alpha PF00503.20 EGB09147.1 - 0.034 13.3 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 EGB09147.1 - 0.037 14.6 0.0 0.12 12.9 0.0 1.9 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 EGB09147.1 - 0.063 13.3 0.0 0.15 12.0 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EGB09147.1 - 0.071 12.9 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGB09147.1 - 0.074 13.4 0.0 0.27 11.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EGB09147.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGB09147.1 - 0.077 12.7 0.1 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein CPT PF07931.12 EGB09147.1 - 0.087 12.7 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Herpes_UL49_2 PF04823.12 EGB09147.1 - 0.95 9.6 4.0 3 8.0 2.5 2.4 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein DHDPS PF00701.22 EGB09148.1 - 4.5e-27 94.5 0.0 5.4e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Sgf11 PF08209.11 EGB09148.1 - 0.067 12.8 0.2 8.5 6.0 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF3721 PF12518.8 EGB09148.1 - 0.21 11.5 2.6 4.3 7.3 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function WD40 PF00400.32 EGB09149.1 - 2e-09 37.9 9.8 0.022 15.6 1.3 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09149.1 - 0.00013 22.2 0.3 3 8.2 0.0 4.1 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Transket_pyr PF02779.24 EGB09150.1 - 3.3e-63 212.6 0.0 1.5e-62 210.4 0.0 2.2 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EGB09150.1 - 6.7e-50 168.7 0.0 1.1e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EGB09150.1 - 4e-48 163.9 0.0 6e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EGB09150.1 - 3.1e-13 49.1 3.8 7.8e-13 47.8 3.8 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus LRR_6 PF13516.6 EGB09151.1 - 0.042 13.9 3.5 2.6 8.3 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Serglycin PF04360.12 EGB09151.1 - 0.099 12.6 0.4 0.2 11.6 0.4 1.4 1 0 0 1 1 1 0 Serglycin Methyltransf_4 PF02390.17 EGB09152.1 - 1.7e-25 89.5 0.0 2.2e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGB09152.1 - 0.078 13.7 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DnaJ PF00226.31 EGB09153.1 - 2.6e-23 81.9 0.7 2.9e-23 81.8 0.7 1.0 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 EGB09154.1 - 8.9e-15 55.0 0.0 7.6e-07 29.6 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB09154.1 - 1.8e-13 50.4 0.0 6.7e-06 26.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB09154.1 - 3.5e-13 49.8 0.1 6.4e-05 23.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB09154.1 - 4e-11 42.1 0.1 0.0063 16.9 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EGB09154.1 - 2.9e-10 40.1 0.1 0.0019 18.5 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat DUF846 PF05832.12 EGB09155.1 - 1.2e-52 177.6 8.2 1.4e-52 177.4 8.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF3267 PF11667.8 EGB09155.1 - 1.2 9.5 10.6 0.34 11.2 0.4 2.1 2 0 0 2 2 2 0 Putative zincin peptidase DUF3493 PF11998.8 EGB09156.1 - 1.6e-21 76.3 0.1 3.3e-21 75.2 0.1 1.6 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 CAP_GLY PF01302.25 EGB09157.1 - 5.9e-22 77.5 0.3 6.4e-22 77.4 0.3 1.0 1 0 0 1 1 1 1 CAP-Gly domain START PF01852.19 EGB09158.1 - 1.8e-08 34.0 0.0 1.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 START domain DUF2754 PF10953.8 EGB09158.1 - 0.078 13.2 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) 2OG-FeII_Oxy_3 PF13640.6 EGB09159.1 - 6.5e-09 36.6 0.0 1.1e-08 35.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB09159.1 - 0.0057 17.1 0.0 0.0097 16.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GlutR_N PF05201.15 EGB09160.1 - 6.2e-36 123.3 0.1 1.2e-35 122.4 0.1 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EGB09160.1 - 1.6e-26 93.0 0.2 3.8e-26 91.8 0.2 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 EGB09160.1 - 7.4e-26 90.4 0.3 5.7e-25 87.6 0.3 2.4 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain Sacchrp_dh_NADP PF03435.18 EGB09160.1 - 1.5e-05 25.2 1.6 7.4e-05 23.0 0.1 2.6 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EGB09160.1 - 0.001 19.6 0.1 0.001 19.6 0.1 2.9 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 EGB09160.1 - 0.03 14.4 0.7 0.13 12.3 0.7 2.2 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGB09160.1 - 0.073 13.9 0.0 0.27 12.0 0.0 2.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold YqfD PF06898.11 EGB09160.1 - 0.098 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD REJ PF02010.15 EGB09161.1 - 5.2e-54 183.7 0.0 1.6e-51 175.6 0.0 2.4 1 1 1 2 2 2 2 REJ domain Laminin_G_3 PF13385.6 EGB09161.1 - 1.4e-11 44.8 3.2 1.5e-11 44.7 1.1 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 EGB09161.1 - 0.0064 16.8 12.5 0.02 15.2 12.5 2.0 1 0 0 1 1 1 1 EGF-like domain GPS PF01825.21 EGB09161.1 - 0.0071 16.9 1.2 0.0071 16.9 1.2 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif EGF PF00008.27 EGB09161.1 - 0.044 14.1 3.9 0.15 12.4 3.9 1.9 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGB09161.1 - 0.082 13.0 6.1 0.39 10.8 6.1 2.2 1 0 0 1 1 1 0 Tenascin EGF domain PKD PF00801.20 EGB09161.1 - 0.088 12.7 2.1 1.8 8.5 0.1 3.4 2 0 0 2 2 2 0 PKD domain CN_hydrolase PF00795.22 EGB09163.1 - 5.5e-23 81.6 0.0 7.3e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asparaginase PF00710.20 EGB09164.1 - 3.5e-55 186.5 0.0 1.9e-54 184.2 0.0 1.9 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGB09164.1 - 2.3e-28 98.7 0.5 5.1e-28 97.6 0.5 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain CAP_N PF01213.19 EGB09164.1 - 4.4 6.7 7.7 6.5 6.1 7.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MORN PF02493.20 EGB09165.1 - 2.3e-31 105.8 36.0 1.5e-07 30.9 0.9 6.1 6 0 0 6 6 6 6 MORN repeat PRKCSH_1 PF13015.6 EGB09166.1 - 1.6e-06 27.8 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PrmA PF06325.13 EGB09168.1 - 2.4e-05 23.9 0.5 4e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Reprolysin_4 PF13583.6 EGB09168.1 - 3e-05 23.7 0.6 7.7e-05 22.4 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EGB09168.1 - 0.00074 20.0 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EGB09168.1 - 0.00085 18.4 3.3 0.0014 17.6 3.3 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_5 PF13688.6 EGB09168.1 - 0.0031 17.7 0.1 0.0031 17.7 0.1 2.1 3 0 0 3 3 3 1 Metallo-peptidase family M12 Methyltransf_23 PF13489.6 EGB09168.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGB09168.1 - 0.038 14.7 0.1 0.17 12.6 0.1 2.2 1 0 0 1 1 1 0 Methyltransferase domain HTH_15 PF12324.8 EGB09168.1 - 0.058 13.4 0.1 0.23 11.5 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Reprolysin_2 PF13574.6 EGB09168.1 - 0.081 12.8 2.9 0.28 11.0 2.9 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Cons_hypoth95 PF03602.15 EGB09168.1 - 0.12 12.1 0.2 0.21 11.2 0.2 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PDZ_6 PF17820.1 EGB09170.1 - 1.4e-49 165.7 9.9 2.2e-05 24.2 0.1 8.6 8 0 0 8 8 8 8 PDZ domain PDZ_2 PF13180.6 EGB09170.1 - 3.2e-40 136.3 0.0 0.0023 18.2 0.0 8.5 8 0 0 8 8 8 8 PDZ domain PDZ PF00595.24 EGB09170.1 - 4.6e-30 103.8 5.9 0.032 14.6 0.0 8.4 8 0 0 8 8 8 8 PDZ domain Arteri_nsp7a PF16749.5 EGB09170.1 - 0.008 16.4 1.8 3.3 7.9 0.1 3.0 3 0 0 3 3 3 2 Arterivirus nonstructural protein 7 alpha DUF4585 PF15232.6 EGB09170.1 - 0.1 12.7 0.2 31 4.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) DUF4213 PF13938.6 EGB09170.1 - 0.19 12.0 2.2 27 5.1 0.0 4.6 4 0 0 4 4 4 0 Putative heavy-metal chelation DUF1996 PF09362.10 EGB09171.1 - 5.2e-49 167.4 0.5 8.3e-49 166.7 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PLAC8 PF04749.17 EGB09171.1 - 6.2e-06 27.1 15.8 1.9e-05 25.6 15.8 1.8 1 1 0 1 1 1 1 PLAC8 family Acyl-ACP_TE PF01643.17 EGB09171.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase YHS PF04945.13 EGB09171.1 - 7.6e-05 22.7 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 YHS domain CaMKII_AD PF08332.10 EGB09172.1 - 2.2e-25 89.3 0.0 2.7e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 EGB09172.1 - 7.6e-06 26.3 0.1 9.5e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EGB09172.1 - 0.0006 20.1 0.0 0.00084 19.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Ion_trans PF00520.31 EGB09173.1 - 1.8e-12 47.0 19.9 4.1e-12 45.9 19.9 1.6 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB09173.1 - 7.2e-09 35.6 0.1 1.6e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CopD PF05425.13 EGB09173.1 - 3.4 8.1 7.1 8.4 6.9 0.5 3.3 3 0 0 3 3 3 0 Copper resistance protein D Cupin_8 PF13621.6 EGB09174.1 - 1.9e-13 50.7 0.0 3.8e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB09174.1 - 4.3e-06 26.4 0.0 8.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGB09174.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase WD40 PF00400.32 EGB09175.1 - 1.4e-11 44.8 0.0 2.2e-07 31.4 0.0 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09175.1 - 8.8e-06 25.9 0.0 0.15 12.3 0.0 2.0 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SNARE PF05739.19 EGB09176.1 - 7.8e-13 48.2 0.2 2.1e-12 46.8 0.2 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGB09176.1 - 4.1e-06 26.6 4.0 0.0024 17.6 0.1 2.2 2 0 0 2 2 2 2 Syntaxin Prominin PF05478.11 EGB09176.1 - 0.00058 18.0 0.3 0.00076 17.6 0.3 1.1 1 0 0 1 1 1 1 Prominin Syntaxin_2 PF14523.6 EGB09176.1 - 0.0038 17.6 1.6 0.048 14.0 0.2 2.3 2 0 0 2 2 2 1 Syntaxin-like protein GTA_holin_3TM PF11351.8 EGB09176.1 - 0.092 13.3 0.6 0.21 12.2 0.1 1.8 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release T2SSF PF00482.23 EGB09176.1 - 0.3 11.0 3.0 0.2 11.6 0.5 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TTL PF03133.15 EGB09177.1 - 1.3e-16 60.6 0.1 2e-15 56.7 0.4 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family FOLN PF09289.10 EGB09177.1 - 0.16 12.2 1.0 0.36 11.0 1.0 1.6 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Cons_hypoth95 PF03602.15 EGB09178.1 - 2.7e-29 102.1 0.0 3.1e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EGB09178.1 - 2.4e-06 28.2 0.2 3.1e-06 27.8 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB09178.1 - 4.1e-05 23.2 0.0 5.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGB09178.1 - 0.00017 21.4 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGB09178.1 - 0.0036 16.9 0.0 0.0047 16.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EGB09178.1 - 0.029 13.8 0.1 0.033 13.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 EGB09178.1 - 0.14 11.8 0.2 0.35 10.5 0.2 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Ribosomal_L7Ae PF01248.26 EGB09179.1 - 4.1e-26 90.5 0.2 5.6e-26 90.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EGB09179.1 - 0.00083 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 EGB09179.1 - 0.021 14.9 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 Na_H_Exchanger PF00999.21 EGB09180.1 - 4.2e-32 111.4 18.0 6.1e-32 110.8 18.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cobW PF02492.19 EGB09182.1 - 2.2e-12 46.9 0.2 2.2e-11 43.7 0.2 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB09182.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_28 PF13521.6 EGB09182.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.15 EGB09182.1 - 0.16 9.9 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein TsaE PF02367.17 EGB09182.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CobA_CobO_BtuR PF02572.15 EGB09182.1 - 0.27 11.5 2.3 0.43 10.8 2.3 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP rRNA_processing PF08524.11 EGB09183.1 - 0.5 10.4 13.4 0.69 9.9 13.4 1.1 1 0 0 1 1 1 0 rRNA processing RNA_pol_Rpc4 PF05132.14 EGB09183.1 - 3.2 8.2 7.1 3.2 8.2 4.0 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Peptidase_S51 PF03575.17 EGB09184.1 - 3.2e-26 92.3 0.0 7.5e-26 91.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S51 NAD_binding_10 PF13460.6 EGB09184.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Cyclin_N PF00134.23 EGB09185.1 - 8.5e-08 32.0 0.1 1.7e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGB09185.1 - 0.0033 17.8 1.0 0.0045 17.4 0.1 1.7 2 0 0 2 2 2 1 Cyclin TPR_14 PF13428.6 EGB09185.1 - 0.014 16.1 1.4 0.075 13.9 0.4 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3730 PF12530.8 EGB09185.1 - 0.02 14.5 0.1 0.17 11.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Pribosyltran PF00156.27 EGB09186.1 - 3.7e-24 85.1 0.0 4.8e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Sugarporin_N PF11471.8 EGB09186.1 - 0.058 13.4 2.8 0.15 12.1 2.8 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Histone_H2A_C PF16211.5 EGB09187.1 - 8.3e-20 70.2 1.4 2e-19 69.0 1.4 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB09187.1 - 5.1e-12 46.3 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB09187.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB09188.1 - 6.1e-53 178.7 1.1 6.8e-53 178.5 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGB09188.1 - 0.00076 20.1 3.0 0.00098 19.7 3.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGB09188.1 - 0.00088 19.4 0.3 0.0014 18.7 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB09188.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGB09188.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGB09188.1 - 0.032 14.3 0.1 0.057 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Mito_carr PF00153.27 EGB09189.1 - 1e-46 156.7 6.2 1.7e-20 72.7 0.0 4.1 2 1 2 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EGB09189.1 - 0.078 12.1 5.2 0.16 11.1 0.1 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Carboxyl_trans PF01039.22 EGB09190.1 - 3e-181 603.4 0.0 4.7e-181 602.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Aldedh PF00171.22 EGB09190.1 - 3.3e-53 180.8 0.9 3.7e-48 164.2 0.0 2.2 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Utp12 PF04003.12 EGB09190.1 - 2.2e-16 60.1 0.2 4.1e-16 59.2 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family OPA3 PF07047.12 EGB09190.1 - 1.4e-06 28.1 0.1 2.8e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) TFB6 PF17110.5 EGB09190.1 - 0.003 17.3 2.0 0.0083 15.9 2.0 1.7 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 EGB09190.1 - 0.0059 16.1 11.9 0.013 15.0 11.9 1.5 1 0 0 1 1 1 1 SDA1 WD40 PF00400.32 EGB09190.1 - 0.0095 16.8 0.4 0.0095 16.8 0.4 4.3 5 0 0 5 5 3 1 WD domain, G-beta repeat BUD22 PF09073.10 EGB09190.1 - 0.011 15.1 13.1 0.0094 15.3 11.3 1.7 2 0 0 2 2 2 0 BUD22 BSP_II PF05432.11 EGB09190.1 - 0.014 15.1 8.5 0.023 14.4 8.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Mpp10 PF04006.12 EGB09190.1 - 0.04 12.4 11.0 0.061 11.8 11.0 1.1 1 0 0 1 1 1 0 Mpp10 protein DRTGG PF07085.12 EGB09190.1 - 0.052 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 DRTGG domain TFIIA PF03153.13 EGB09190.1 - 0.094 12.7 16.7 0.17 11.9 16.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EGB09190.1 - 0.41 8.8 21.6 0.63 8.2 21.6 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 EGB09190.1 - 0.5 10.2 12.7 1.5 8.7 12.7 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 EGB09190.1 - 0.53 8.3 34.4 0.8 7.7 34.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EGB09190.1 - 0.54 9.4 11.1 1 8.5 11.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4637 PF15470.6 EGB09190.1 - 1.2 8.8 10.6 2.9 7.6 10.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SAPS PF04499.15 EGB09190.1 - 1.3 7.7 3.5 2.1 7.0 3.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 EGB09190.1 - 1.7 6.8 15.9 2.7 6.2 15.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 EGB09190.1 - 3.3 7.5 9.5 3.1 7.6 5.4 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein YCII PF03795.14 EGB09191.1 - 7.1e-07 29.6 0.5 0.0013 19.1 0.0 2.8 2 0 0 2 2 2 2 YCII-related domain Prenyltrans PF00432.21 EGB09193.1 - 1.2e-15 57.0 9.9 2.3e-06 27.3 1.2 4.4 4 1 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat RhoGAP PF00620.27 EGB09194.1 - 4.8e-29 101.1 0.0 7e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain EF-hand_7 PF13499.6 EGB09194.1 - 1.1e-08 35.4 0.0 2.4e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB09194.1 - 1.7e-06 27.5 1.8 0.034 14.1 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGB09194.1 - 0.0002 20.7 6.0 0.0006 19.2 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 EGB09194.1 - 0.0012 18.2 1.4 0.065 12.8 0.0 2.8 2 0 0 2 2 2 1 EF hand DAPDH_C PF16654.5 EGB09194.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain EF-hand_8 PF13833.6 EGB09194.1 - 0.37 10.7 4.1 0.45 10.4 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair GTP_EFTU PF00009.27 EGB09195.1 - 4.4e-59 199.3 0.1 5.8e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGB09195.1 - 9.5e-30 103.2 0.0 1.8e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGB09195.1 - 3.9e-18 65.6 2.4 9.7e-18 64.3 2.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGB09195.1 - 1.3e-05 25.3 0.1 5.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 EGB09195.1 - 0.012 15.2 0.1 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EGB09195.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 EGB09195.1 - 0.057 13.2 0.2 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MAP65_ASE1 PF03999.12 EGB09195.1 - 0.42 9.3 0.6 0.6 8.7 0.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RRM_1 PF00076.22 EGB09196.1 - 6e-18 64.4 0.0 7.2e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB09196.1 - 0.00012 22.2 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 EGB09196.1 - 0.019 14.8 0.0 0.071 13.0 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGB09196.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PEPcase PF00311.17 EGB09197.1 - 3.3e-235 782.9 0.0 4.3e-235 782.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase CutC PF03932.14 EGB09197.1 - 2.7e-18 66.2 0.1 6.3e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 CutC family DUF5639 PF18690.1 EGB09197.1 - 0.046 13.9 0.5 0.89 9.8 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5639) PEPcase_2 PF14010.6 EGB09197.1 - 0.28 9.6 0.0 0.43 9.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase IATP PF04568.12 EGB09198.1 - 0.66 10.4 6.8 0.062 13.7 1.1 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP ABC_tran PF00005.27 EGB09200.1 - 1.1e-48 165.2 0.0 2.8e-23 82.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EGB09200.1 - 5.7e-26 91.4 4.7 2.1e-11 43.5 0.0 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EGB09200.1 - 2.1e-14 54.0 1.1 0.00011 22.1 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB09200.1 - 1.5e-05 25.5 0.3 0.2 12.0 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGB09200.1 - 1.5e-05 24.6 0.1 0.24 11.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB09200.1 - 4.1e-05 24.2 0.0 0.029 14.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGB09200.1 - 0.00074 19.5 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MukB PF04310.12 EGB09200.1 - 0.001 19.0 0.6 0.46 10.3 0.1 2.2 2 0 0 2 2 2 2 MukB N-terminal ABC2_membrane PF01061.24 EGB09200.1 - 0.0036 16.8 19.5 0.075 12.4 10.4 2.6 2 1 0 2 2 2 2 ABC-2 type transporter MMR_HSR1 PF01926.23 EGB09200.1 - 0.0055 16.8 0.2 1.9 8.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF4162 PF13732.6 EGB09200.1 - 0.011 16.4 0.0 2.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_30 PF13604.6 EGB09200.1 - 0.012 15.3 0.1 0.98 9.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGB09200.1 - 0.082 13.2 0.0 22 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EGB09200.1 - 0.13 11.9 0.1 12 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain UQ_con PF00179.26 EGB09201.1 - 1.6e-21 76.5 0.0 1.6e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGB09201.1 - 0.0014 18.4 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 EGB09201.1 - 0.016 15.5 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 EGB09201.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 CTP_transf_like PF01467.26 EGB09202.1 - 9.6e-07 29.1 0.0 2e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like Rad60-SLD PF11976.8 EGB09202.1 - 5e-06 26.2 0.1 7.7e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like VCBS PF13517.6 EGB09203.1 - 1.2e-25 89.8 65.4 5.3e-09 36.5 7.2 5.8 1 1 4 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PPR_2 PF13041.6 EGB09203.1 - 3.3e-13 49.6 0.0 7e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 EGB09203.1 - 1.1e-08 35.1 0.0 5.9e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGB09203.1 - 1.3e-05 24.7 0.0 2.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGB09203.1 - 6.7e-05 22.9 0.0 0.002 18.3 0.0 2.8 2 0 0 2 2 2 1 PPR repeat AbfS_sensor PF18225.1 EGB09203.1 - 0.044 13.7 0.0 23 5.0 0.0 4.0 4 0 0 4 4 4 0 Sensor histidine kinase (AbfS) sensor domain Dockerin_1 PF00404.18 EGB09203.1 - 8.8 6.6 29.2 2.4 8.4 6.0 4.7 3 1 1 4 4 4 0 Dockerin type I domain BBS1 PF14779.6 EGB09204.1 - 1.6e-90 303.0 0.0 5e-89 298.1 0.0 2.6 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 EGB09204.1 - 0.0017 18.3 0.0 0.54 10.3 0.0 2.6 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region UxuA PF03786.13 EGB09205.1 - 4.3e-116 387.6 0.0 5.1e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 D-mannonate dehydratase (UxuA) AP_endonuc_2 PF01261.24 EGB09205.1 - 2.7e-13 49.8 0.0 9.5e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel GAS PF13851.6 EGB09206.1 - 3.7e-66 222.3 15.7 3.7e-66 222.3 15.7 3.3 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EGB09206.1 - 0.0016 18.7 10.6 0.0016 18.7 10.6 4.3 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) DUF4172 PF13776.6 EGB09206.1 - 0.17 12.2 4.2 1.1 9.7 0.2 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4172) Baculo_PEP_C PF04513.12 EGB09206.1 - 2.6 8.1 8.0 1.9 8.5 0.8 3.5 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ion_trans_2 PF07885.16 EGB09207.1 - 9.1e-10 38.4 7.4 2.3e-09 37.1 7.4 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB09207.1 - 3.9e-06 26.3 6.3 6e-06 25.7 6.3 1.2 1 0 0 1 1 1 1 Ion transport protein CCDC66 PF15236.6 EGB09207.1 - 0.00087 19.2 14.4 0.00087 19.2 14.4 2.6 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 66 TFIIA PF03153.13 EGB09207.1 - 8.7 6.2 9.7 0.26 11.3 3.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Patatin PF01734.22 EGB09208.1 - 1.2e-19 71.3 7.4 1.2e-19 71.3 7.4 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase Exostosin PF03016.15 EGB09208.1 - 0.0051 16.1 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Methyltransf_12 PF08242.12 EGB09209.1 - 1.1e-13 51.8 0.0 2.6e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB09209.1 - 1.2e-13 51.6 0.2 2.7e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09209.1 - 2e-11 44.0 0.0 2.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09209.1 - 8.8e-11 42.3 0.2 2e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB09209.1 - 6.8e-05 22.7 0.0 8.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB09209.1 - 0.029 13.9 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EGB09209.1 - 0.046 13.2 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase CheR PF01739.18 EGB09209.1 - 0.051 13.1 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 EGB09209.1 - 0.081 12.2 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain AMP-binding PF00501.28 EGB09210.1 - 5.7e-82 275.6 0.4 7.1e-82 275.3 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB09210.1 - 3.7e-21 75.9 0.1 2.4e-19 70.1 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGB09210.1 - 9.7e-17 60.6 0.4 1.5e-15 56.9 0.4 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Cupin_8 PF13621.6 EGB09211.1 - 7.4e-06 25.9 0.0 0.069 12.9 0.0 2.3 1 1 1 2 2 2 2 Cupin-like domain EamA PF00892.20 EGB09212.1 - 2.3e-07 31.1 25.9 4.4e-05 23.7 9.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 EGB09212.1 - 2.9 6.1 11.5 0.64 8.2 8.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 EGB09212.1 - 6 6.5 11.8 0.22 11.2 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PALP PF00291.25 EGB09213.1 - 1.9e-41 142.4 3.5 1.9e-41 142.4 3.5 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.20 EGB09213.1 - 1.2e-12 47.2 0.1 1.7e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PcrB PF01884.17 EGB09213.1 - 0.042 13.3 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 PcrB family His_biosynth PF00977.21 EGB09213.1 - 0.047 13.1 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Lon_C PF05362.13 EGB09215.1 - 2.1e-67 226.7 0.0 3.3e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGB09215.1 - 1.3e-20 74.2 0.0 2.4e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 EGB09215.1 - 1.7e-19 70.5 0.0 3.3e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 EGB09215.1 - 5.5e-09 35.9 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 EGB09215.1 - 2.8e-05 23.2 0.0 4.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_5 PF07728.14 EGB09215.1 - 4.8e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGB09215.1 - 0.00056 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGB09215.1 - 0.0007 19.9 0.4 0.043 14.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB09215.1 - 0.012 16.0 0.1 0.012 16.0 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain Phage_connect_1 PF05135.13 EGB09215.1 - 0.021 15.3 0.0 0.05 14.1 0.0 1.7 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein AAA_30 PF13604.6 EGB09215.1 - 0.049 13.3 0.4 0.18 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGB09215.1 - 0.057 13.9 2.9 0.82 10.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB09215.1 - 0.067 13.7 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGB09215.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ArgJ PF01960.18 EGB09215.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 ArgJ family AAA_33 PF13671.6 EGB09215.1 - 0.14 12.3 0.1 0.39 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain CPSF73-100_C PF11718.8 EGB09216.1 - 6.1e-35 120.7 0.0 9e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EGB09216.1 - 3.9e-29 101.2 0.0 7e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EGB09216.1 - 2.7e-14 52.8 0.0 7.9e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Hydrolase_4 PF12146.8 EGB09216.1 - 1.6e-09 37.4 0.0 3.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lactamase_B_6 PF16661.5 EGB09216.1 - 3.4e-07 29.9 0.0 6.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EGB09216.1 - 0.0046 17.0 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta_lactamase3 PF17030.5 EGB09216.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative beta-lactamase-like family Peptidase_M76 PF09768.9 EGB09217.1 - 1.1e-48 165.2 0.1 1.3e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 Peptidase M76 family DDE_5 PF13546.6 EGB09217.1 - 0.052 12.9 0.1 0.052 12.9 0.1 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease Peptidase_M91 PF14891.6 EGB09217.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Effector protein SUZ PF12752.7 EGB09217.1 - 0.13 13.0 1.1 0.25 12.1 1.1 1.4 1 0 0 1 1 1 0 SUZ domain Cep57_CLD PF14073.6 EGB09218.1 - 0.028 14.4 13.7 0.039 14.0 13.7 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 HHV-5_US34A PF17087.5 EGB09218.1 - 1.3 9.2 6.0 0.18 12.0 0.8 2.3 2 0 0 2 2 2 0 Herpesvirus US34A protein family Pkinase PF00069.25 EGB09219.1 - 2.7e-19 69.6 0.0 3.1e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09219.1 - 5.4e-08 32.4 0.0 6.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Bac_globin PF01152.21 EGB09220.1 - 0.00023 21.3 0.0 0.00023 21.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial-like globin DUF1194 PF06707.11 EGB09221.1 - 0.11 11.6 0.2 2.7 7.1 0.2 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1194) Abhydrolase_1 PF00561.20 EGB09222.1 - 7.1e-07 29.1 0.1 2.5e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB09222.1 - 0.083 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ketoacyl-synt PF00109.26 EGB09223.1 - 3e-49 167.9 4.5 3e-49 167.9 4.5 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB09223.1 - 4.2e-36 123.5 1.4 1.1e-35 122.2 1.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain UCR_UQCRX_QCR9 PF05365.12 EGB09224.1 - 0.24 11.4 2.0 11 6.1 0.1 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DNA_pol_B_palm PF14792.6 EGB09225.1 - 0.00063 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm NTP_transf_2 PF01909.23 EGB09225.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF1295 PF06966.12 EGB09226.1 - 7e-17 61.7 0.4 1.3e-16 60.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Folate_carrier PF01770.18 EGB09227.1 - 4.5e-27 94.8 0.0 2.2e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Reduced folate carrier NmrA PF05368.13 EGB09227.1 - 1.7e-12 47.4 0.0 6.2e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGB09227.1 - 1.6e-07 31.4 4.5 1.6e-07 31.4 4.5 2.3 2 0 0 2 2 2 1 NAD(P)H-binding MFS_1_like PF12832.7 EGB09227.1 - 1.4e-05 24.1 0.4 6.7e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 MFS_1 like family MFS_1 PF07690.16 EGB09227.1 - 3.9e-05 22.7 22.7 3.9e-05 22.7 22.7 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Macro PF01661.21 EGB09228.1 - 0.0073 16.3 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Macro domain MaoC_dehydratas PF01575.19 EGB09229.1 - 1.9e-20 72.6 0.4 3e-20 72.0 0.4 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGB09229.1 - 0.025 14.7 0.0 0.061 13.5 0.0 1.7 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase KH_1 PF00013.29 EGB09230.1 - 1.8e-12 46.9 0.0 1.8e-09 37.3 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EGB09230.1 - 0.00042 20.1 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EGB09230.1 - 0.025 14.4 0.1 0.095 12.6 0.0 1.9 2 0 0 2 2 2 0 KH domain LRR_4 PF12799.7 EGB09231.1 - 1.4e-09 38.1 0.3 0.0036 17.7 0.0 4.8 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB09231.1 - 1.1e-08 34.6 2.3 0.035 13.9 0.5 3.6 2 1 0 3 3 3 3 Leucine rich repeat HHH_3 PF12836.7 EGB09231.1 - 2e-08 34.3 0.0 5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif PsbU PF06514.11 EGB09231.1 - 5.1e-07 29.6 0.0 9.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) LRR_1 PF00560.33 EGB09231.1 - 8.8e-05 22.5 0.3 39 5.4 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 EGB09231.1 - 0.0022 17.9 0.9 48 4.4 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Peptidase_C2 PF00648.21 EGB09232.1 - 4e-25 88.5 0.0 4.7e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease TMEM18 PF14770.6 EGB09233.1 - 2.2e-37 127.6 1.1 2.6e-37 127.4 1.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 Ion_trans PF00520.31 EGB09234.1 - 3e-15 56.1 5.8 4.5e-15 55.6 5.8 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB09236.1 - 1.6e-11 44.1 0.1 3.1e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB09236.1 - 7.4e-10 38.5 10.5 1.4e-09 37.6 10.5 1.4 1 1 0 1 1 1 1 Ion transport protein SpoVAB PF13782.6 EGB09236.1 - 0.002 18.4 1.4 0.0077 16.5 0.2 2.2 2 0 0 2 2 2 1 Stage V sporulation protein AB Ion_trans_N PF08412.10 EGB09236.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal LMF1 PF06762.14 EGB09237.1 - 3.6e-41 141.7 0.0 1.3e-33 116.8 0.0 2.0 1 1 1 2 2 2 2 Lipase maturation factor Band_7 PF01145.25 EGB09238.1 - 5e-31 108.1 0.6 7.1e-31 107.6 0.6 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Flot PF15975.5 EGB09238.1 - 1.1 9.5 7.2 0.47 10.7 4.1 1.9 2 0 0 2 2 2 0 Flotillin Pro_isomerase PF00160.21 EGB09239.1 - 4.3e-31 108.3 0.0 4.8e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.17 EGB09241.1 - 9.1e-26 90.3 0.0 1e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Glyco_hydro_31 PF01055.26 EGB09242.1 - 1e-45 156.7 0.0 1.3e-45 156.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 zf-RING_2 PF13639.6 EGB09244.1 - 2.8e-12 46.8 3.7 5.5e-12 45.8 3.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB09244.1 - 4e-09 36.2 2.6 7.9e-09 35.2 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB09244.1 - 1.2e-08 34.6 2.0 2.1e-08 33.9 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB09244.1 - 1.8e-08 34.5 4.2 5.5e-08 33.0 4.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGB09244.1 - 5.4e-08 32.6 2.9 1.1e-07 31.6 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGB09244.1 - 2.6e-07 30.3 1.7 2.6e-07 30.3 1.7 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGB09244.1 - 8.1e-07 29.0 0.1 1.8e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGB09244.1 - 1e-06 28.6 2.7 2e-06 27.6 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGB09244.1 - 1.2e-06 28.5 1.1 2.6e-06 27.4 1.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGB09244.1 - 2e-06 27.3 3.4 4.2e-06 26.3 3.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGB09244.1 - 8.1e-06 25.6 3.3 1.7e-05 24.5 3.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 EGB09244.1 - 0.00091 19.3 3.8 0.0026 17.9 3.7 1.9 1 1 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EGB09244.1 - 0.0024 18.0 5.5 0.022 15.0 5.5 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EGB09244.1 - 0.0066 16.6 1.7 0.019 15.1 1.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGB09244.1 - 0.016 15.0 1.0 0.025 14.4 1.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.6 EGB09244.1 - 0.098 12.8 0.6 0.098 12.8 0.6 1.9 2 1 0 2 2 2 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 EGB09244.1 - 0.17 12.3 3.1 0.34 11.2 3.1 1.6 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.6 EGB09244.1 - 0.34 11.2 2.4 0.45 10.8 0.3 2.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain DUF3040 PF11239.8 EGB09244.1 - 9.7 6.5 7.9 0.7 10.2 0.2 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF3040) Sel1 PF08238.12 EGB09245.1 - 7.9e-28 96.3 23.0 1.9e-05 25.1 0.8 6.3 6 0 0 6 6 6 6 Sel1 repeat Flu_M1_C PF08289.11 EGB09245.1 - 0.079 13.2 0.0 41 4.5 0.0 3.3 1 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain TPR_14 PF13428.6 EGB09245.1 - 0.26 12.2 11.7 9.9 7.3 0.1 5.5 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09245.1 - 0.28 11.5 3.4 0.34 11.2 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RSN1_7TM PF02714.15 EGB09246.1 - 5e-26 91.6 24.8 6.9e-26 91.2 24.8 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGB09246.1 - 2.9e-13 50.4 0.7 4.2e-05 23.8 0.0 4.0 5 0 0 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGB09246.1 - 1.4e-06 28.2 0.2 3.9e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 EGB09246.1 - 8.8e-05 21.5 0.6 8.8e-05 21.5 0.6 2.5 3 0 0 3 3 3 1 Calcium-activated chloride channel zf-C2H2_jaz PF12171.8 EGB09246.1 - 0.35 11.2 11.9 1.4e+02 2.9 0.0 8.3 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding zf-CpG_bind_C PF12269.8 EGB09246.1 - 1.2 8.8 24.7 4.1 7.1 0.3 8.2 8 2 2 10 10 10 0 CpG binding protein zinc finger C terminal domain LRR_8 PF13855.6 EGB09248.1 - 3.3e-14 52.4 17.7 0.00013 21.7 3.9 4.1 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EGB09248.1 - 1.6e-10 41.1 19.1 0.034 14.6 0.2 4.3 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) DUF3557 PF12078.8 EGB09248.1 - 0.071 13.1 1.0 0.17 11.9 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3557) zf-RING_2 PF13639.6 EGB09250.1 - 1.1e-08 35.3 6.8 1.1e-08 35.3 6.8 2.1 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 EGB09250.1 - 3.2e-05 24.1 9.8 5.2e-05 23.5 4.8 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGB09250.1 - 0.00018 21.2 4.3 0.00019 21.1 0.4 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGB09250.1 - 0.00041 20.1 7.2 0.00041 20.1 7.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB09250.1 - 0.011 15.6 3.3 0.011 15.6 3.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGB09250.1 - 0.038 14.0 7.8 0.062 13.4 3.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGB09250.1 - 0.23 11.3 6.7 0.1 12.5 3.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGB09250.1 - 0.34 11.1 3.7 0.95 9.6 3.7 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.6 EGB09250.1 - 0.58 10.2 11.2 0.11 12.5 6.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EGB09250.1 - 1.6 8.4 8.2 0.13 12.0 2.6 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EGB09250.1 - 4.2 7.3 10.2 0.32 10.9 4.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BRCA2 PF00634.18 EGB09251.1 - 1.6e-11 43.6 20.6 0.41 10.3 0.1 8.2 8 0 0 8 8 8 5 BRCA2 repeat DUF2786 PF10979.8 EGB09251.1 - 2.3e-07 30.6 22.1 7.4 6.6 0.1 9.3 8 0 0 8 8 8 2 Protein of unknown function (DUF2786) Rad51 PF08423.11 EGB09251.1 - 9.8e-07 28.3 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Rad51 Rep-A_N PF04057.12 EGB09251.1 - 4.7e-05 23.3 0.0 9.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain AAA_16 PF13191.6 EGB09251.1 - 0.0048 17.3 2.5 0.014 15.8 2.5 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGB09251.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Nse4-Nse3_bdg PF15412.6 EGB09251.1 - 0.063 13.4 15.6 93 3.2 0.0 7.4 8 0 0 8 8 8 0 Binding domain of Nse4/EID3 to Nse3-MAGE ABC_tran PF00005.27 EGB09251.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.17 EGB09251.1 - 0.21 11.6 0.2 0.33 11.0 0.2 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_30 PF13604.6 EGB09251.1 - 2.7 7.7 8.0 11 5.7 8.0 2.0 1 1 0 1 1 1 0 AAA domain Ephrin_rec_like PF07699.13 EGB09252.1 - 1.5e-18 66.2 67.3 3.1e-05 23.6 1.9 9.1 4 2 5 10 10 10 8 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB09252.1 - 0.039 14.4 41.6 0.94 9.9 0.0 8.4 7 2 1 8 8 8 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EGB09253.1 - 5.1e-14 51.8 14.5 1.7e-06 27.7 1.8 3.3 1 1 2 3 3 3 3 Putative ephrin-receptor like NCD3G PF07562.14 EGB09253.1 - 6.4e-07 29.2 8.0 0.024 14.6 0.1 3.2 2 1 2 4 4 4 3 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EGB09253.1 - 1.1e-05 25.7 4.9 0.13 12.6 0.1 3.5 2 1 1 3 3 3 2 TNFR/NGFR cysteine-rich region VSP PF03302.13 EGB09253.1 - 0.036 12.9 27.0 0.14 11.0 13.8 2.0 1 1 1 2 2 2 0 Giardia variant-specific surface protein DUF2318 PF10080.9 EGB09253.1 - 3.7 7.7 11.8 5.9 7.1 0.3 3.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) Nup214_FG PF18617.1 EGB09253.1 - 4.9 7.7 17.7 1.6 9.3 1.0 3.7 1 1 3 4 4 4 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Ephrin_rec_like PF07699.13 EGB09254.1 - 6.8e-33 112.2 60.1 5.5e-06 26.1 4.7 7.9 3 2 2 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EGB09254.1 - 4e-07 29.9 29.6 0.61 10.1 0.5 7.5 6 1 0 7 7 7 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EGB09254.1 - 0.011 16.1 43.2 2.6 8.5 0.3 7.9 7 0 0 7 7 7 0 TNFR/NGFR cysteine-rich region HSBP1 PF06825.12 EGB09255.1 - 4.8e-27 93.6 5.2 5.5e-27 93.4 5.2 1.0 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 EGB09255.1 - 0.0032 17.8 0.3 0.0039 17.5 0.3 1.2 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 EGB09255.1 - 0.0086 16.5 0.5 0.016 15.7 0.5 1.4 1 1 0 1 1 1 1 Cell division protein ZapB GvpK PF05121.12 EGB09255.1 - 0.013 15.5 0.5 0.017 15.1 0.5 1.2 1 0 0 1 1 1 0 Gas vesicle protein K Prefoldin_2 PF01920.20 EGB09255.1 - 0.013 15.4 0.4 0.017 15.1 0.4 1.0 1 0 0 1 1 1 0 Prefoldin subunit YvrJ PF12841.7 EGB09255.1 - 0.015 14.8 0.6 0.079 12.5 0.2 2.0 2 0 0 2 2 2 0 YvrJ protein family BLOC1_2 PF10046.9 EGB09255.1 - 0.018 15.3 0.2 0.024 15.0 0.2 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Erythro-docking PF09277.11 EGB09255.1 - 0.03 14.2 0.2 0.05 13.5 0.2 1.5 1 1 0 1 1 1 0 Erythronolide synthase, docking XhlA PF10779.9 EGB09255.1 - 0.041 14.1 0.8 0.072 13.3 0.8 1.4 1 1 0 1 1 1 0 Haemolysin XhlA Tektin PF03148.14 EGB09255.1 - 0.048 12.4 0.2 0.058 12.2 0.2 1.0 1 0 0 1 1 1 0 Tektin family Baculo_PEP_C PF04513.12 EGB09255.1 - 0.058 13.4 0.3 0.068 13.2 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FtsK_SpoIIIE PF01580.18 EGB09255.1 - 0.061 12.7 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family FlxA PF14282.6 EGB09255.1 - 0.072 13.1 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF1664 PF07889.12 EGB09255.1 - 0.08 13.0 0.2 0.088 12.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 EGB09255.1 - 0.081 12.3 0.1 0.095 12.0 0.1 1.0 1 0 0 1 1 1 0 FAM76 protein Fzo_mitofusin PF04799.13 EGB09255.1 - 0.082 12.4 0.3 0.094 12.3 0.3 1.0 1 0 0 1 1 1 0 fzo-like conserved region ABC_tran_CTD PF16326.5 EGB09255.1 - 0.13 12.5 0.9 0.39 11.0 0.8 1.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain PMI_typeI PF01238.21 EGB09256.1 - 7.5e-55 186.6 0.0 3.7e-53 181.0 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EGB09256.1 - 0.1 12.4 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Cupin domain peroxidase PF00141.23 EGB09257.1 - 2.9e-09 37.0 0.2 0.0018 18.0 0.0 2.5 2 0 0 2 2 2 2 Peroxidase Aldo_ket_red PF00248.21 EGB09257.1 - 6.6e-08 32.1 0.0 9.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EGB09258.1 - 8.7e-14 51.4 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family APG6_N PF17675.1 EGB09258.1 - 1.2e-08 35.6 9.0 4.6e-05 24.0 2.8 2.2 2 0 0 2 2 2 2 Apg6 coiled-coil region ShK PF01549.24 EGB09258.1 - 9.5e-05 22.9 5.2 9.5e-05 22.9 5.2 4.6 3 1 0 3 3 2 1 ShK domain-like Filament PF00038.21 EGB09258.1 - 9.5e-05 22.1 6.0 0.039 13.5 0.1 2.1 2 0 0 2 2 2 2 Intermediate filament protein ATG16 PF08614.11 EGB09258.1 - 0.00036 20.8 11.2 0.041 14.1 3.9 2.4 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) DUF812 PF05667.11 EGB09258.1 - 0.00042 19.3 0.4 0.041 12.8 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF812) PT PF04886.12 EGB09258.1 - 0.00062 19.3 24.3 0.00062 19.3 24.3 2.3 1 1 1 2 2 2 2 PT repeat AAA_13 PF13166.6 EGB09258.1 - 0.0011 17.8 5.3 0.25 9.9 0.1 2.1 2 0 0 2 2 2 2 AAA domain Fib_alpha PF08702.10 EGB09258.1 - 0.0012 19.1 0.1 0.49 10.6 0.2 2.6 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family CENP-H PF05837.12 EGB09258.1 - 0.0013 19.1 9.7 0.28 11.6 7.1 2.2 2 0 0 2 2 2 1 Centromere protein H (CENP-H) HMMR_N PF15905.5 EGB09258.1 - 0.002 17.7 14.1 0.0064 16.0 9.2 2.5 2 1 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 EGB09258.1 - 0.0021 18.1 1.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) SlyX PF04102.12 EGB09258.1 - 0.0026 18.4 4.8 0.019 15.6 0.1 3.0 2 1 0 2 2 2 1 SlyX GAS PF13851.6 EGB09258.1 - 0.0032 16.9 7.6 0.093 12.1 3.2 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 EGB09258.1 - 0.0056 16.7 12.2 0.04 14.0 2.5 3.1 2 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase HAUS-augmin3 PF14932.6 EGB09258.1 - 0.006 16.2 6.3 0.028 14.0 4.0 2.0 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 EGB09258.1 - 0.0075 15.7 12.9 0.43 9.9 7.9 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) ZapB PF06005.12 EGB09258.1 - 0.0082 16.6 15.6 1.3 9.5 0.4 3.2 2 1 0 2 2 2 1 Cell division protein ZapB YlqD PF11068.8 EGB09258.1 - 0.0086 16.4 1.3 0.75 10.2 0.5 2.3 2 0 0 2 2 2 1 YlqD protein DUF3450 PF11932.8 EGB09258.1 - 0.013 14.8 5.8 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Troponin PF00992.20 EGB09258.1 - 0.017 15.4 2.7 0.28 11.5 0.0 2.4 2 1 0 2 2 2 0 Troponin TMF_DNA_bd PF12329.8 EGB09258.1 - 0.018 15.0 12.7 0.1 12.6 0.2 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 EGB09258.1 - 0.019 15.1 8.2 0.62 10.1 0.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 EGB09258.1 - 0.02 15.1 9.4 0.41 10.9 4.8 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.7 EGB09258.1 - 0.027 14.6 18.6 0.028 14.6 0.3 2.4 2 1 0 2 2 2 0 Tropomyosin like Fez1 PF06818.15 EGB09258.1 - 0.029 14.8 3.1 1.5 9.2 2.3 2.1 2 0 0 2 2 2 0 Fez1 TFA2_Winged_2 PF18121.1 EGB09258.1 - 0.046 13.4 2.2 3.9 7.2 0.1 2.6 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Jnk-SapK_ap_N PF09744.9 EGB09258.1 - 0.048 13.9 6.1 0.98 9.6 3.2 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 EGB09258.1 - 0.054 12.4 10.0 1 8.1 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 EGB09258.1 - 0.054 13.3 7.3 0.84 9.4 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Cep57_CLD PF14073.6 EGB09258.1 - 0.06 13.4 4.7 3.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DivIC PF04977.15 EGB09258.1 - 0.071 12.9 13.8 2.1 8.2 0.3 3.8 2 2 1 3 3 3 0 Septum formation initiator Tropomyosin PF00261.20 EGB09258.1 - 0.087 12.2 21.3 0.6 9.4 13.2 2.4 2 1 0 2 2 2 0 Tropomyosin TPD52 PF04201.15 EGB09258.1 - 0.1 12.2 0.2 0.1 12.2 0.2 2.2 2 0 0 2 2 2 0 Tumour protein D52 family Phage_GP20 PF06810.11 EGB09258.1 - 0.11 12.3 16.2 0.43 10.4 0.2 2.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 BST2 PF16716.5 EGB09258.1 - 0.11 13.0 8.1 1.1 9.9 5.1 2.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF5082 PF16888.5 EGB09258.1 - 0.13 12.5 8.2 3.5 7.9 1.8 3.0 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) DUF3584 PF12128.8 EGB09258.1 - 0.18 9.3 8.8 0.29 8.6 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PRKG1_interact PF15898.5 EGB09258.1 - 0.37 11.7 7.6 0.35 11.8 4.0 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain MAD PF05557.13 EGB09258.1 - 0.41 8.9 4.1 6.5 5.0 0.0 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein YabA PF06156.13 EGB09258.1 - 0.42 11.3 2.2 20 5.9 2.0 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Prefoldin_2 PF01920.20 EGB09258.1 - 0.42 10.6 11.4 1.8 8.5 0.3 3.1 2 1 1 3 3 3 0 Prefoldin subunit bZIP_2 PF07716.15 EGB09258.1 - 0.48 10.6 12.9 6.2 7.0 0.1 4.7 2 2 3 5 5 5 0 Basic region leucine zipper T3SS_needle_E PF08988.10 EGB09258.1 - 0.55 10.4 6.7 1.9 8.7 2.3 3.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Baculo_PEP_C PF04513.12 EGB09258.1 - 0.63 10.1 5.0 3.1 7.9 1.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tektin PF03148.14 EGB09258.1 - 1.5 7.5 7.4 6.4 5.4 0.0 2.4 2 1 0 2 2 2 0 Tektin family DASH_Spc19 PF08287.11 EGB09258.1 - 1.5 8.7 4.1 17 5.3 2.6 2.3 2 0 0 2 2 2 0 Spc19 DUF4140 PF13600.6 EGB09258.1 - 1.7 9.2 16.9 3.4 8.2 0.3 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ABC_tran_CTD PF16326.5 EGB09258.1 - 1.7 8.9 30.3 2.8 8.2 5.7 3.8 2 2 2 4 4 4 0 ABC transporter C-terminal domain HrpB7 PF09486.10 EGB09258.1 - 2.2 8.7 21.4 0.29 11.5 0.6 3.2 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 EGB09258.1 - 2.4 8.2 11.5 18 5.3 6.8 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 EGB09258.1 - 2.5 8.5 7.5 8.1 6.8 0.4 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF4472 PF14739.6 EGB09258.1 - 3.3 8.5 9.5 2.9 8.7 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) ERM PF00769.19 EGB09258.1 - 3.6 7.3 15.0 3.1 7.5 8.2 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family BCAS2 PF05700.11 EGB09258.1 - 4.2 7.0 8.7 6.1 6.5 0.6 2.4 2 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) SOGA PF11365.8 EGB09258.1 - 5.3 8.2 6.6 13 7.0 2.3 3.0 2 2 1 3 3 3 0 Protein SOGA PEARLI-4 PF05278.12 EGB09258.1 - 5.3 6.5 8.9 6.9 6.2 0.2 2.1 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Myosin_tail_1 PF01576.19 EGB09258.1 - 9 4.0 15.1 2.9 5.6 9.1 2.0 2 0 0 2 2 2 0 Myosin tail Sel1 PF08238.12 EGB09259.1 - 2.4e-21 75.7 11.5 2.3e-06 28.1 0.1 4.4 4 1 0 4 4 4 4 Sel1 repeat DUF3416 PF11896.8 EGB09259.1 - 0.095 13.0 0.2 10 6.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3416) Cmc1 PF08583.10 EGB09260.1 - 2.8e-13 49.7 1.7 3.3e-13 49.5 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 EGB09260.1 - 0.018 14.8 1.6 0.024 14.3 1.6 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 EGB09260.1 - 0.19 12.1 3.7 0.34 11.3 0.9 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pkinase PF00069.25 EGB09261.1 - 1.1e-12 47.9 0.0 1.2e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09261.1 - 4.4e-06 26.2 0.0 4.8e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 EGB09262.1 - 3.3e-33 113.6 0.3 1.7e-16 60.0 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain RGS PF00615.19 EGB09262.1 - 9.6e-08 32.3 0.0 2.3e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain TPR_2 PF07719.17 EGB09262.1 - 0.025 14.7 8.3 0.18 12.0 0.9 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF724 PF05266.14 EGB09262.1 - 0.21 11.4 0.9 0.52 10.1 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TPR_12 PF13424.6 EGB09262.1 - 5 7.5 8.9 5.7 7.3 5.4 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 EGB09263.1 - 1.1e-19 70.4 9.0 2.7e-08 34.2 0.1 4.5 4 1 0 4 4 4 3 Sel1 repeat VIT PF08487.10 EGB09263.1 - 0.01 16.0 2.1 0.87 9.8 0.2 2.3 2 1 0 2 2 2 0 Vault protein inter-alpha-trypsin domain TetR_C_31 PF17940.1 EGB09263.1 - 0.027 14.7 4.3 1.6 8.9 0.2 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TPR_2 PF07719.17 EGB09263.1 - 5.9 7.3 9.3 14 6.1 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Ion_trans PF00520.31 EGB09264.1 - 4.9e-14 52.2 0.8 5e-14 52.1 0.8 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 EGB09265.1 - 3.2e-104 347.5 52.9 1.5e-52 178.2 14.9 3.0 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 EGB09265.1 - 1.4e-05 24.0 46.7 0.01 14.5 1.8 5.9 6 1 1 7 7 7 5 Polycystin cation channel TFIIS_C PF01096.18 EGB09267.1 - 2e-19 69.1 1.6 2e-19 69.1 1.6 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 EGB09267.1 - 0.0014 18.5 1.2 0.023 14.7 0.3 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain DZR PF12773.7 EGB09267.1 - 0.018 15.0 0.2 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-DNA_Pol PF08996.10 EGB09267.1 - 0.076 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Opy2 PF09463.10 EGB09267.1 - 0.6 10.5 4.9 0.66 10.4 0.0 2.8 3 0 0 3 3 3 0 Opy2 protein Nudix_N_2 PF14803.6 EGB09267.1 - 3.3 7.7 8.2 1.1 9.3 0.1 3.0 3 1 0 3 3 3 0 Nudix N-terminal CTP_transf_1 PF01148.20 EGB09268.1 - 7.7e-56 189.8 13.6 2.7e-55 188.0 13.6 1.7 1 1 0 1 1 1 1 Cytidylyltransferase family Ank_4 PF13637.6 EGB09269.1 - 1.8e-17 63.5 0.4 1.7e-13 50.8 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB09269.1 - 7.7e-15 54.8 0.2 4.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB09269.1 - 1.8e-14 53.4 0.8 2.5e-06 27.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB09269.1 - 2e-13 49.2 0.1 2e-06 27.7 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGB09269.1 - 1.2e-12 48.2 0.0 5.1e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Sulfatase PF00884.23 EGB09270.1 - 1.8e-39 136.0 0.0 3.3e-39 135.1 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB09270.1 - 0.0033 17.1 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF829 PF05705.14 EGB09271.1 - 2.1e-08 34.4 0.0 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Metallophos PF00149.28 EGB09272.1 - 4.9e-34 118.6 0.1 6.3e-34 118.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGB09272.1 - 0.00025 21.4 0.1 0.0005 20.5 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGB09272.1 - 0.027 14.6 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 EGB09272.1 - 0.048 13.3 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Cofilin_ADF PF00241.20 EGB09273.1 - 0.051 13.4 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Amidohydro_3 PF07969.11 EGB09274.1 - 3e-84 284.2 24.1 3.4e-84 284.0 24.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EGB09274.1 - 3.2e-09 36.6 0.3 6.7e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Ank_2 PF12796.7 EGB09275.1 - 4.1e-05 24.1 0.0 9.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB09275.1 - 0.0035 17.9 0.0 0.055 14.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SIMPL PF04402.14 EGB09275.1 - 0.008 16.7 0.3 0.013 15.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Ank_3 PF13606.6 EGB09275.1 - 0.019 15.5 0.1 0.89 10.3 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EGB09275.1 - 0.044 14.1 0.3 0.2 12.0 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB09276.1 - 6.4e-23 81.1 0.9 1.3e-10 41.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09276.1 - 1.8e-22 77.0 1.1 2.1e-05 24.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGB09276.1 - 1e-19 70.3 7.6 2.6e-09 37.1 0.3 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB09276.1 - 5.5e-19 68.3 2.6 2.5e-08 34.3 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB09276.1 - 2e-17 62.8 6.4 0.00029 21.1 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Neur_chan_memb PF02932.16 EGB09277.1 - 0.00049 20.2 0.4 0.00056 20.0 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HisKA_7TM PF16927.5 EGB09277.1 - 0.0054 16.8 0.5 0.0057 16.7 0.5 1.0 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase DUF4060 PF13269.6 EGB09277.1 - 0.042 13.9 0.3 0.069 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) DUF3377 PF11857.8 EGB09277.1 - 0.88 9.5 4.2 0.49 10.4 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) OCD_Mu_crystall PF02423.15 EGB09278.1 - 1.5e-42 145.7 1.0 1.7e-42 145.5 1.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EGB09278.1 - 0.0019 18.3 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EGB09278.1 - 0.0026 18.3 0.0 0.0062 17.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGB09278.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IN_DBD_C PF00552.21 EGB09278.1 - 0.1 11.9 0.1 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 Integrase DNA binding domain bVLRF1 PF18826.1 EGB09279.1 - 7.2e-34 116.8 1.3 7.3e-34 116.8 0.0 1.6 2 0 0 2 2 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 EGB09279.1 - 3.7e-13 49.1 0.9 6e-13 48.4 0.9 1.4 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_5 PF13857.6 EGB09279.1 - 9.1e-08 32.2 0.2 1.9e-07 31.2 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB09279.1 - 4.4e-05 23.7 0.2 0.00031 21.0 0.2 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGB09279.1 - 0.00012 22.6 0.5 0.023 15.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB09279.1 - 0.00032 21.2 0.3 0.00082 19.9 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09279.1 - 0.0004 20.6 0.2 0.002 18.5 0.0 2.4 2 0 0 2 2 1 1 Ankyrin repeat NinG PF05766.12 EGB09279.1 - 0.023 14.6 5.3 0.038 13.9 5.3 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein zf-MYND PF01753.18 EGB09279.1 - 0.16 12.1 0.8 0.34 11.0 0.8 1.5 1 0 0 1 1 1 0 MYND finger FYDLN_acid PF09538.10 EGB09279.1 - 4.8 7.9 25.6 2 9.1 5.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) RR_TM4-6 PF06459.12 EGB09279.1 - 8.8 6.1 6.6 15 5.3 6.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S46 PF10459.9 EGB09280.1 - 9.2e-137 457.6 0.0 1.1e-136 457.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase S46 Trypsin_2 PF13365.6 EGB09280.1 - 1.5e-14 55.1 0.4 3.7e-06 27.9 0.2 3.5 2 1 0 2 2 2 2 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 EGB09280.1 - 0.16 11.2 0.2 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DAP_epimerase PF01678.19 EGB09281.1 - 6.1e-59 197.5 2.7 4e-30 104.5 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase Radical_SAM PF04055.21 EGB09282.1 - 1.6e-14 54.6 0.0 3.4e-14 53.6 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 EGB09282.1 - 0.002 18.2 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain LRR_8 PF13855.6 EGB09283.1 - 3.2e-60 199.8 51.4 2.6e-10 39.9 1.2 7.2 4 1 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EGB09283.1 - 1.6e-40 136.4 41.6 5.9e-07 29.7 0.8 8.1 2 2 9 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB09283.1 - 1.9e-10 40.5 4.7 0.026 14.0 0.1 4.6 1 1 4 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 EGB09283.1 - 4.8e-07 29.8 0.0 0.22 11.5 0.0 3.5 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) Tnp_DNA_bind PF14706.6 EGB09283.1 - 3.6e-06 26.7 0.0 52 3.8 0.0 8.6 2 2 11 13 13 13 0 Transposase DNA-binding MitoNEET_N PF10660.9 EGB09283.1 - 7.4e-06 25.9 12.8 88 3.2 0.0 11.2 2 1 11 14 14 14 0 Iron-containing outer mitochondrial membrane protein N-terminus STAT1_TAZ2bind PF12162.8 EGB09283.1 - 3.9e-05 23.1 0.0 32 4.2 0.0 8.1 12 0 0 12 12 12 0 STAT1 TAZ2 binding domain DASH_Dam1 PF08653.10 EGB09283.1 - 6.4e-05 22.7 18.3 2.6 7.9 0.1 8.1 3 2 5 9 9 9 2 DASH complex subunit Dam1 LRR_1 PF00560.33 EGB09283.1 - 0.0014 18.9 40.3 2.3 9.1 0.1 12.0 14 0 0 14 14 13 1 Leucine Rich Repeat HypF_C PF17788.1 EGB09283.1 - 0.0017 19.0 0.0 18 6.1 0.0 4.8 1 1 6 7 7 7 0 HypF Kae1-like domain Cys_Met_Meta_PP PF01053.20 EGB09283.1 - 0.0054 15.3 3.6 13 4.2 0.0 6.0 2 2 5 8 8 8 1 Cys/Met metabolism PLP-dependent enzyme DUF4363 PF14276.6 EGB09283.1 - 0.015 15.4 0.0 74 3.5 0.0 4.4 1 1 4 6 6 6 0 Domain of unknown function (DUF4363) LRR_4 PF12799.7 EGB09284.1 - 2.7e-07 30.8 1.0 0.00039 20.7 0.6 2.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB09284.1 - 8.7e-07 28.6 2.0 0.019 14.7 0.0 2.4 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EGB09284.1 - 0.01 16.3 7.7 19 6.3 4.0 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EGB09284.1 - 0.31 11.2 2.4 20 5.6 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeat MtN3_slv PF03083.16 EGB09285.1 - 3.2e-24 84.8 4.0 2.4e-14 53.1 0.7 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange UBA PF00627.31 EGB09286.1 - 4.3e-08 32.9 2.5 0.00065 19.5 0.3 2.7 2 0 0 2 2 2 2 UBA/TS-N domain SH3_9 PF14604.6 EGB09286.1 - 2.9e-06 27.1 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 EGB09286.1 - 5.6e-06 26.1 0.6 1.7e-05 24.6 0.6 1.9 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 EGB09286.1 - 2.9e-05 23.6 0.0 5.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PDZ PF00595.24 EGB09286.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain T3SS_needle_E PF08988.10 EGB09286.1 - 0.54 10.4 0.0 0.54 10.4 0.0 2.6 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle TPD PF14811.6 EGB09287.1 - 1.6e-24 86.3 0.0 1.7e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif TAL_effector PF03377.13 EGB09287.1 - 0.11 12.9 0.1 0.24 11.7 0.0 1.6 2 0 0 2 2 2 0 TAL effector repeat RNB PF00773.19 EGB09288.1 - 3.2e-94 315.9 0.0 4.3e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EGB09288.1 - 4.9e-19 68.1 0.0 8.6e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EGB09288.1 - 6.4e-06 26.5 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EGB09288.1 - 0.00026 21.1 0.0 0.00083 19.5 0.0 1.9 1 0 0 1 1 1 1 Cold shock domain Rrp44_S1 PF17215.3 EGB09288.1 - 0.0014 18.5 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 S1 domain Dis3l2_C_term PF17877.1 EGB09288.1 - 0.0093 16.3 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal F-box_5 PF18511.1 EGB09289.1 - 0.086 12.4 0.1 26 4.5 0.0 2.8 2 0 0 2 2 2 0 F-box PhyH PF05721.13 EGB09290.1 - 1.4e-21 77.8 0.4 1.1e-20 74.8 0.4 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_16 PF00722.21 EGB09291.1 - 9.2e-21 74.1 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGB09291.1 - 5.7e-08 31.6 0.0 3e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) RrnaAD PF00398.20 EGB09293.1 - 9.8e-42 142.8 0.0 1.2e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 EGB09293.1 - 0.00049 20.0 0.0 0.0006 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB09293.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_33 PF10017.9 EGB09293.1 - 0.006 15.8 0.0 0.0091 15.2 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 EGB09293.1 - 0.053 14.2 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09293.1 - 0.086 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PELOTA_1 PF15608.6 EGB09293.1 - 0.09 12.7 0.2 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 PELOTA RNA binding domain 2-Hacid_dh_C PF02826.19 EGB09294.1 - 3.2e-49 166.7 0.0 4.7e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGB09294.1 - 2.5e-23 82.2 0.0 3.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGB09294.1 - 2.9e-05 24.3 0.0 6.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase WD40 PF00400.32 EGB09295.1 - 5.1e-06 27.1 8.9 0.0025 18.6 0.2 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat SGL PF08450.12 EGB09295.1 - 0.0033 17.1 0.1 0.0092 15.6 0.0 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DAGAT PF03982.13 EGB09296.1 - 4.6e-28 98.0 0.0 6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Nucleotid_trans PF03407.16 EGB09297.1 - 2.7e-08 34.1 0.0 1e-07 32.2 0.0 2.1 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase WD40 PF00400.32 EGB09298.1 - 8.7e-09 35.9 9.2 4e-07 30.6 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Sel1 PF08238.12 EGB09299.1 - 1.5e-24 85.8 10.9 2.3e-08 34.4 0.1 4.3 4 1 0 4 4 4 4 Sel1 repeat FumaraseC_C PF10415.9 EGB09299.1 - 0.14 12.6 0.5 0.94 9.9 0.1 2.1 2 0 0 2 2 2 0 Fumarase C C-terminus TPR_16 PF13432.6 EGB09299.1 - 0.23 12.1 13.8 1 10.1 6.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PSD5 PF07637.11 EGB09299.1 - 0.24 11.8 2.5 1.2 9.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1595) TPR_12 PF13424.6 EGB09299.1 - 0.46 10.8 10.3 0.64 10.4 2.0 3.8 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB09299.1 - 1.6 9.1 18.4 0.62 10.3 1.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB09299.1 - 2 8.4 13.3 0.82 9.6 0.2 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB09299.1 - 5.3 7.9 8.3 57 4.7 0.7 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_S9 PF00326.21 EGB09300.1 - 0.00022 20.8 1.4 0.00025 20.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGB09300.1 - 0.00062 19.7 6.8 0.00084 19.3 4.4 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ank_2 PF12796.7 EGB09300.1 - 0.0053 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PhyH PF05721.13 EGB09301.1 - 5.6e-38 131.3 0.0 1.1e-37 130.4 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Kinesin PF00225.23 EGB09302.1 - 1.1e-68 231.7 0.0 1.2e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB09302.1 - 4.1e-06 26.8 0.0 6.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 EGB09302.1 - 0.19 12.1 5.6 0.23 11.8 3.2 2.3 1 1 1 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 EGB09303.1 - 3.9e-30 104.8 0.1 4.3e-30 104.7 0.1 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGB09303.1 - 0.00016 21.8 0.0 0.00023 21.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGB09303.1 - 0.0076 15.6 0.0 0.0091 15.3 0.0 1.1 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 EGB09303.1 - 0.077 12.4 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit HSF_DNA-bind PF00447.17 EGB09304.1 - 5.3e-20 71.8 0.1 6.3e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Oxidored_molyb PF00174.19 EGB09305.1 - 3.8e-46 156.8 0.0 6.3e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGB09305.1 - 2.1e-44 150.9 0.0 3.8e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 EGB09305.1 - 7.6e-26 90.4 0.0 1.7e-25 89.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EGB09305.1 - 4e-22 78.1 0.0 1.1e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 EGB09305.1 - 3e-18 66.5 0.0 7.4e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGB09305.1 - 0.0071 16.5 0.0 0.77 9.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 EGB09306.1 - 1.3e-38 133.0 0.4 2.6e-38 131.9 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EGB09306.1 - 3.2e-16 59.1 0.0 6.1e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 EGB09306.1 - 4.3e-15 55.6 0.0 1.4e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 EGB09306.1 - 1.8e-14 54.0 0.0 4.3e-13 49.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 EGB09306.1 - 5.2e-14 52.3 9.5 4.5e-12 46.1 5.9 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 EGB09306.1 - 3.9e-12 45.8 0.0 3.4e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 EGB09306.1 - 1e-09 38.2 0.0 3.8e-09 36.4 0.0 2.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 EGB09306.1 - 3.1e-05 23.8 0.0 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain AlaDh_PNT_C PF01262.21 EGB09306.1 - 0.058 12.7 0.7 0.12 11.6 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EGB09306.1 - 0.073 13.3 0.1 0.61 10.4 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGB09306.1 - 0.24 10.5 0.9 0.43 9.6 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGB09306.1 - 0.62 9.3 2.5 12 5.1 0.2 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB09306.1 - 3 6.8 9.1 1 8.3 1.6 2.7 3 0 0 3 3 3 0 FAD binding domain DUF2237 PF09996.9 EGB09307.1 - 1.2e-47 160.7 0.0 1.3e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Peptidase_C97 PF05903.14 EGB09308.1 - 7.9e-22 77.7 0.0 8.7e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain 2OG-FeII_Oxy_3 PF13640.6 EGB09310.1 - 3.3e-12 47.1 0.0 6.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 EGB09310.1 - 2.3e-06 28.0 3.4 1e-05 25.9 3.4 2.2 1 0 0 1 1 1 1 ShK domain-like ParA PF10609.9 EGB09311.1 - 1.3e-84 283.5 0.0 3.1e-79 265.9 0.0 2.0 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGB09311.1 - 1.2e-11 44.7 0.0 3.5e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EGB09311.1 - 9.4e-08 31.6 0.0 7.8e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 EGB09311.1 - 1.1e-07 31.9 0.0 1.2e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EGB09311.1 - 2.1e-07 30.5 0.5 1.2e-06 27.9 0.2 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 EGB09311.1 - 4.5e-05 23.1 0.1 0.00013 21.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EGB09311.1 - 0.0023 17.0 0.2 0.0037 16.3 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 EGB09311.1 - 0.003 17.0 0.0 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EGB09311.1 - 0.012 15.5 0.7 0.82 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 EGB09311.1 - 0.012 15.1 0.1 0.052 13.0 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 EGB09311.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 EGB09311.1 - 0.048 13.6 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EGB09311.1 - 0.13 11.9 0.0 0.77 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EGB09311.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 EGB09311.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EGB09311.1 - 0.17 11.8 0.2 0.59 10.0 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 EGB09311.1 - 0.17 11.0 0.1 0.36 10.0 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.10 EGB09311.1 - 0.29 10.5 0.0 0.44 9.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DEAD PF00270.29 EGB09312.1 - 8.4e-45 152.7 0.0 1.3e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB09312.1 - 1.4e-20 73.7 0.0 4.2e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 EGB09312.1 - 3e-14 53.1 0.0 7.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 EGB09312.1 - 2e-05 24.7 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGB09312.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MFS_1 PF07690.16 EGB09314.1 - 7.7e-17 61.2 26.3 1.4e-16 60.4 26.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily EF-hand_7 PF13499.6 EGB09315.1 - 1.9e-17 63.4 9.0 4.2e-10 39.9 0.7 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB09315.1 - 2.7e-17 60.9 6.0 1.3e-05 24.4 1.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGB09315.1 - 1.5e-16 58.8 3.9 0.00053 19.7 0.3 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EGB09315.1 - 6.4e-14 51.5 4.9 2.5e-06 27.2 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_11 PF08976.11 EGB09315.1 - 3.4e-09 37.5 0.4 0.0032 18.3 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB09315.1 - 1.9e-07 30.2 2.4 0.062 12.8 0.5 3.6 3 0 0 3 3 3 3 EF hand EF-hand_10 PF14788.6 EGB09315.1 - 0.00032 20.5 4.1 0.0015 18.4 2.0 2.7 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EGB09315.1 - 0.00056 20.2 3.0 0.58 10.5 0.0 3.3 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGB09315.1 - 0.19 11.7 1.3 21 5.1 0.1 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand APG9 PF04109.16 EGB09316.1 - 3.6e-46 158.2 0.6 5.3e-46 157.6 0.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 ANAPC4_WD40 PF12894.7 EGB09316.1 - 1.5e-08 34.8 0.2 3.4 8.0 0.0 6.7 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EGB09316.1 - 8e-08 32.3 8.1 1.2 9.0 0.1 6.8 5 1 2 7 7 7 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 EGB09316.1 - 6.5e-07 28.7 1.5 0.13 11.3 0.0 4.0 4 0 0 4 4 4 2 Coatomer WD associated region Nic96 PF04097.14 EGB09316.1 - 0.00036 19.1 0.1 0.53 8.7 0.0 2.8 2 1 0 2 2 2 2 Nup93/Nic96 TPR_2 PF07719.17 EGB09316.1 - 0.007 16.4 29.7 8.3 6.8 0.4 9.1 9 1 1 10 10 10 3 Tetratricopeptide repeat PPR_2 PF13041.6 EGB09316.1 - 0.03 14.5 2.8 3.4 7.9 0.0 4.3 4 0 0 4 4 4 0 PPR repeat family TPR_8 PF13181.6 EGB09316.1 - 0.042 14.1 6.0 85 3.8 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 EGB09316.1 - 0.96 10.4 0.0 0.96 10.4 0.0 5.6 8 0 0 8 8 5 0 WD domain, G-beta repeat TPR_11 PF13414.6 EGB09316.1 - 1.2 8.9 6.4 13 5.6 0.6 3.9 3 1 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 EGB09316.1 - 1.4 9.9 32.8 6.2 7.9 0.6 10.0 10 2 0 10 10 9 0 Tetratricopeptide repeat MIT PF04212.18 EGB09316.1 - 1.6 8.8 14.7 5.9 7.0 0.2 5.1 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EGB09316.1 - 3.7 7.8 27.4 1.7 8.8 0.0 8.2 8 1 0 8 8 8 0 Tetratricopeptide repeat Nucleotid_trans PF03407.16 EGB09318.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 EGB09318.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family WD40 PF00400.32 EGB09320.1 - 0.00068 20.4 0.1 5.2 8.1 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase PF00069.25 EGB09321.1 - 1.2e-64 218.2 0.0 1.6e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09321.1 - 3.9e-37 127.9 0.0 5.3e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09321.1 - 0.0034 16.8 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGB09321.1 - 0.0069 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Arb2 PF09757.9 EGB09321.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Arb2 domain Pkinase_fungal PF17667.1 EGB09321.1 - 0.028 13.2 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGB09321.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGB09322.1 - 1.6e-63 214.6 0.0 1.8e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09322.1 - 2.6e-26 92.5 0.0 3.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB09322.1 - 0.0053 16.1 0.1 0.0076 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB09322.1 - 0.015 15.2 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family EIF_2_alpha PF07541.12 EGB09323.1 - 2.3e-39 134.1 0.1 4.4e-39 133.2 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGB09323.1 - 1.7e-12 47.5 0.2 2.8e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Cmc1 PF08583.10 EGB09323.1 - 0.028 14.4 0.4 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like EcKinase PF02958.20 EGB09323.1 - 0.051 12.9 0.6 0.11 11.8 0.0 1.8 3 0 0 3 3 3 0 Ecdysteroid kinase WcbI PF18588.1 EGB09324.1 - 0.039 13.6 0.5 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI Elongin_A PF06881.11 EGB09324.1 - 1.8 9.2 6.7 0.34 11.5 2.7 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A V_ATPase_I PF01496.19 EGB09325.1 - 6.2e-238 791.8 0.0 3.6e-173 577.6 0.0 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DHR10 PF18595.1 EGB09325.1 - 0.35 10.9 4.8 0.46 10.6 2.4 2.2 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DUF3246 PF11596.8 EGB09326.1 - 0.12 11.8 4.0 0.032 13.7 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Ribosomal_60s PF00428.19 EGB09327.1 - 3.4 8.3 10.7 5.8 7.6 10.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Acetyltransf_1 PF00583.25 EGB09328.1 - 3.5e-07 30.5 0.0 9.2e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AA_kinase PF00696.28 EGB09328.1 - 1.3e-06 28.2 2.1 2.1e-06 27.5 2.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_7 PF13508.7 EGB09328.1 - 6e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain bPH_6 PF10756.9 EGB09328.1 - 0.034 14.2 0.6 0.18 11.9 0.6 2.3 1 0 0 1 1 1 0 Bacterial PH domain Acetyltransf_10 PF13673.7 EGB09328.1 - 0.039 13.9 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TOBE_3 PF12857.7 EGB09329.1 - 0.011 15.7 1.0 4.4 7.3 0.2 3.2 1 1 1 2 2 2 0 TOBE-like domain Phage_GP20 PF06810.11 EGB09329.1 - 0.16 11.8 3.0 4.3 7.1 0.0 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 FAM163 PF15069.6 EGB09329.1 - 0.37 11.2 1.5 1.4 9.4 0.0 2.6 3 0 0 3 3 3 0 FAM163 family Bombinin PF05298.11 EGB09329.1 - 1.4 8.6 8.4 0.55 9.9 1.3 3.1 3 0 0 3 3 3 0 Bombinin MT PF12777.7 EGB09330.1 - 6.6e-06 25.4 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor zf-RING_9 PF13901.6 EGB09331.1 - 4e-14 53.1 0.0 1.1e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Apo-CIII PF05778.12 EGB09332.1 - 0.16 11.6 0.4 0.68 9.6 0.0 2.3 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) Bromodomain PF00439.25 EGB09333.1 - 6.8e-18 64.5 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Form_Nir_trans PF01226.17 EGB09334.1 - 2.2e-43 148.3 14.5 4.5e-43 147.3 14.5 1.4 1 0 0 1 1 1 1 Formate/nitrite transporter NIF PF03031.18 EGB09334.1 - 8e-15 54.9 0.0 1.8e-14 53.8 0.0 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase MAPEG PF01124.18 EGB09335.1 - 5.1e-15 55.5 1.8 6.3e-15 55.2 1.8 1.1 1 0 0 1 1 1 1 MAPEG family P22_AR_C PF10548.9 EGB09335.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 P22AR C-terminal domain Kinesin PF00225.23 EGB09336.1 - 1.4e-115 385.8 0.0 1.4e-115 385.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGB09336.1 - 2e-27 95.9 0.1 4.1e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 EGB09336.1 - 0.0053 16.9 8.4 0.013 15.6 6.6 2.3 1 1 1 2 2 2 1 Kinesin-associated LMBR1 PF04791.16 EGB09336.1 - 0.28 10.0 7.6 0.41 9.5 7.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 EGB09336.1 - 0.39 10.8 3.2 0.4 10.7 0.7 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 EGB09336.1 - 1.1 8.7 18.1 0.75 9.3 15.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit TPR_1 PF00515.28 EGB09337.1 - 1.6e-15 56.1 3.5 2.7e-05 23.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB09337.1 - 9.2e-10 37.9 6.9 0.00017 21.5 0.1 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGB09337.1 - 6.1e-08 32.7 1.9 2.6e-07 30.7 1.9 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB09337.1 - 4.1e-07 29.9 0.8 0.013 15.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB09337.1 - 6e-06 25.9 6.3 0.0018 17.9 0.1 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 EGB09337.1 - 5.1e-05 23.2 5.2 0.018 15.2 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09337.1 - 0.00014 22.3 9.4 0.057 13.9 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09337.1 - 0.0042 17.7 1.2 0.0042 17.7 1.2 3.9 1 1 2 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09337.1 - 0.019 15.2 1.0 0.019 15.2 1.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB09337.1 - 0.044 14.6 0.5 0.044 14.6 0.5 4.7 1 1 3 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB09337.1 - 0.11 12.6 0.3 2.3 8.4 0.0 2.4 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EGB09337.1 - 0.15 12.2 1.6 4.8 7.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pirin PF02678.16 EGB09338.1 - 3.3e-22 78.5 0.7 5.1e-22 77.9 0.7 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGB09338.1 - 3.2e-17 62.8 0.0 6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain KH_1 PF00013.29 EGB09340.1 - 4.6e-30 103.3 1.6 4e-16 58.6 0.1 2.1 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EGB09340.1 - 2.8e-08 33.5 0.6 0.0012 18.6 0.2 2.2 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 EGB09340.1 - 7.1e-08 32.2 0.2 0.014 15.3 0.0 2.3 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.5 EGB09340.1 - 0.024 14.6 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 KH-like RNA-binding domain DUF2530 PF10745.9 EGB09340.1 - 0.026 14.7 0.3 5.6 7.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Peptidase_S24 PF00717.23 EGB09340.1 - 0.06 13.3 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase S24-like KH_5 PF13184.6 EGB09340.1 - 0.19 11.8 1.5 13 5.9 0.1 2.3 2 0 0 2 2 2 0 NusA-like KH domain Sel1 PF08238.12 EGB09341.1 - 1e-37 127.7 24.3 3.1e-08 34.0 0.2 8.5 8 2 0 8 8 8 6 Sel1 repeat TPR_12 PF13424.6 EGB09341.1 - 2e-08 34.4 19.2 0.00049 20.3 0.7 5.1 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB09341.1 - 3.1e-07 30.0 20.7 0.0036 17.1 0.4 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB09341.1 - 3.6e-05 23.5 20.6 0.00055 19.8 1.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGB09341.1 - 0.00043 20.1 13.8 0.01 15.8 0.1 5.5 6 1 0 6 6 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09341.1 - 0.0006 19.5 0.6 0.0006 19.5 0.6 6.8 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09341.1 - 0.00092 19.8 12.9 0.0029 18.2 2.8 5.2 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09341.1 - 0.0016 18.5 15.5 0.021 15.0 0.2 6.8 8 1 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB09341.1 - 0.0052 17.0 1.2 0.011 16.0 0.2 2.1 3 0 0 3 3 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EGB09341.1 - 0.0064 16.8 5.3 0.91 9.9 0.2 3.7 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB09341.1 - 0.0065 17.2 24.5 0.007 17.1 0.3 6.2 5 1 2 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09341.1 - 0.014 15.8 1.0 0.014 15.8 1.0 4.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_5 PF12688.7 EGB09341.1 - 0.11 12.7 9.0 1.7 8.9 0.1 4.4 2 1 3 5 5 5 0 Tetratrico peptide repeat RPN7 PF10602.9 EGB09341.1 - 0.14 11.9 0.1 0.37 10.5 0.1 1.9 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 EGB09341.1 - 0.24 11.9 5.0 25 5.5 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB09341.1 - 0.77 10.5 13.6 1.7 9.4 0.4 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 EGB09341.1 - 2.2 8.4 8.7 2.6 8.2 0.2 4.5 7 0 0 7 7 5 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 EGB09341.1 - 4.4 7.1 11.3 1.2 8.9 0.3 4.7 5 1 0 5 5 5 0 TPR repeat NSF PF02071.20 EGB09341.1 - 6.7 8.0 10.9 5.5 8.2 0.2 5.1 6 0 0 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat Exo_endo_phos PF03372.23 EGB09342.1 - 0.00036 20.1 0.0 0.0011 18.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGB09342.1 - 0.0017 18.2 0.0 2 8.3 0.0 2.9 3 1 0 3 3 3 2 Endonuclease-reverse transcriptase LRR_6 PF13516.6 EGB09343.1 - 4.4e-15 54.4 11.0 0.34 11.1 0.0 8.9 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 EGB09343.1 - 3.7e-10 39.9 0.0 0.79 10.2 0.0 5.0 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB09343.1 - 0.0053 17.1 5.8 11 7.0 0.8 5.5 4 2 1 5 5 5 2 Leucine Rich Repeat LRR_2 PF07723.13 EGB09343.1 - 5.4 7.9 0.0 5.4 7.9 0.0 4.6 7 0 0 7 7 7 0 Leucine Rich Repeat VWA_2 PF13519.6 EGB09344.1 - 0.047 14.3 0.0 0.13 12.9 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 EGB09344.1 - 0.058 13.6 0.0 0.56 10.4 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain AIM24 PF01987.17 EGB09345.1 - 4.6e-20 72.3 0.8 5.4e-20 72.1 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 zf-CCCH PF00642.24 EGB09346.1 - 4.5e-13 48.7 36.4 2.2e-05 24.2 1.2 5.8 4 3 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGB09346.1 - 3.2e-08 33.4 26.0 0.003 17.6 2.2 6.3 5 1 0 5 5 5 3 Zinc finger domain zf-CCCH_4 PF18044.1 EGB09346.1 - 0.00014 21.5 33.5 0.0084 15.9 1.5 5.8 5 2 0 5 5 5 4 CCCH-type zinc finger Torus PF16131.5 EGB09346.1 - 0.0014 19.3 13.4 0.011 16.4 1.1 3.5 3 1 0 3 3 3 3 Torus domain ABC_membrane PF00664.23 EGB09347.1 - 4.9e-59 200.2 10.3 2.2e-34 119.4 1.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGB09347.1 - 3.3e-44 150.7 0.0 1.6e-24 87.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGB09347.1 - 9.4e-10 38.3 2.2 0.0016 17.9 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 EGB09347.1 - 6.1e-05 23.1 0.7 0.098 12.7 0.3 2.4 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 EGB09347.1 - 7.6e-05 22.4 1.0 0.096 12.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB09347.1 - 0.00021 21.6 1.5 0.31 11.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGB09347.1 - 0.00025 21.1 0.4 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 EGB09347.1 - 0.00047 20.3 3.0 0.38 10.8 0.8 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 EGB09347.1 - 0.0031 17.9 4.7 1.3 9.4 0.2 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 EGB09347.1 - 0.0064 16.3 5.0 0.25 11.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB09347.1 - 0.0071 16.3 1.0 0.99 9.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EGB09347.1 - 0.019 14.6 6.0 0.78 9.3 2.3 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EGB09347.1 - 0.042 14.1 0.1 22 5.3 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGB09347.1 - 0.049 13.0 0.5 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 EGB09347.1 - 0.062 12.8 2.4 0.19 11.2 0.3 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein Nif11 PF07862.11 EGB09347.1 - 0.084 13.2 0.2 0.36 11.2 0.2 2.1 1 0 0 1 1 1 0 Nif11 domain AAA_23 PF13476.6 EGB09347.1 - 0.32 11.5 0.1 18 5.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB09347.1 - 0.32 10.9 1.0 21 5.0 0.3 2.5 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 EGB09347.1 - 0.73 9.1 2.0 22 4.3 0.1 2.3 2 0 0 2 2 2 0 AIG1 family EF-hand_7 PF13499.6 EGB09348.1 - 2.2e-13 50.4 5.7 7.5e-09 35.9 1.9 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB09348.1 - 6.7e-13 47.4 3.5 0.0003 20.5 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGB09348.1 - 2.7e-12 45.3 7.9 0.002 17.6 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGB09348.1 - 1.1e-05 25.2 10.3 0.0091 15.8 2.9 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB09348.1 - 2e-05 23.8 12.6 0.069 12.7 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EGB09348.1 - 0.033 14.5 0.2 0.11 12.9 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_14 PF17959.1 EGB09348.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 EGB09348.1 - 1.9 8.5 5.5 21 5.1 0.1 3.0 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand MatE PF01554.18 EGB09349.1 - 4e-26 91.6 15.0 2.6e-15 56.4 3.5 2.4 2 0 0 2 2 2 2 MatE Beta_helix PF13229.6 EGB09349.1 - 0.22 11.4 5.1 1.2 8.9 5.1 2.2 1 1 0 1 1 1 0 Right handed beta helix region DUF3456 PF11938.8 EGB09349.1 - 0.64 10.5 3.2 0.43 11.1 0.2 2.0 1 1 1 2 2 2 0 TLR4 regulator and MIR-interacting MSAP UPF0020 PF01170.18 EGB09350.1 - 3.9e-30 105.0 0.0 5.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 EGB09350.1 - 6.3e-05 23.1 0.0 9.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 THUMP domain MTS PF05175.14 EGB09350.1 - 0.0051 16.4 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain SnoaL_2 PF12680.7 EGB09350.1 - 0.028 15.0 0.2 0.11 13.1 0.2 2.0 1 0 0 1 1 1 0 SnoaL-like domain SRP54 PF00448.22 EGB09351.1 - 2.8e-54 183.7 0.0 4.5e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EGB09351.1 - 2.4e-23 83.5 7.2 7.7e-23 81.8 7.2 1.7 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 EGB09351.1 - 5.8e-11 42.5 0.8 2e-10 40.7 0.8 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 EGB09351.1 - 2.1e-05 25.0 2.0 0.0012 19.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB09351.1 - 9.6e-05 22.7 0.1 0.00031 21.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EGB09351.1 - 0.00038 20.2 1.7 0.0004 20.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain KdpD PF02702.17 EGB09351.1 - 0.001 18.6 0.3 0.0042 16.6 0.0 2.2 3 0 0 3 3 3 1 Osmosensitive K+ channel His kinase sensor domain MeaB PF03308.16 EGB09351.1 - 0.0015 17.6 2.4 0.0027 16.8 0.1 2.4 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGB09351.1 - 0.0015 18.4 0.1 0.018 15.0 0.1 2.4 1 1 0 1 1 1 1 NTPase MMR_HSR1 PF01926.23 EGB09351.1 - 0.0033 17.5 0.3 0.038 14.1 0.3 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGB09351.1 - 0.0047 17.1 0.5 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGB09351.1 - 0.0063 16.9 0.0 0.0063 16.9 0.0 3.0 3 1 0 3 3 3 1 AAA domain DUF2052 PF09747.9 EGB09351.1 - 0.01 16.0 7.8 0.02 15.0 7.8 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) CDC27 PF09507.10 EGB09351.1 - 0.016 14.6 6.1 0.027 13.9 6.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CbiA PF01656.23 EGB09351.1 - 0.018 15.1 0.0 0.085 12.9 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 EGB09351.1 - 0.02 15.3 0.0 0.086 13.3 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fer4_NifH PF00142.18 EGB09351.1 - 0.032 13.7 0.1 0.07 12.6 0.0 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_14 PF13173.6 EGB09351.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain CinA_KH PF18146.1 EGB09351.1 - 0.46 10.7 5.8 3.1 8.0 0.0 3.3 3 0 0 3 3 3 0 Damage-inducible protein CinA KH domain SspB PF04386.13 EGB09351.1 - 1.6 8.6 4.9 3.8 7.4 4.9 1.6 1 0 0 1 1 1 0 Stringent starvation protein B DUF973 PF06157.11 EGB09352.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Thioredoxin PF00085.20 EGB09353.1 - 7.4e-14 51.6 0.0 8.9e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB09353.1 - 4.6e-05 23.8 0.2 0.00017 22.0 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGB09353.1 - 0.0007 19.9 0.0 0.0058 16.9 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 EGB09353.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGB09353.1 - 0.016 15.4 0.1 0.022 14.9 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 EGB09353.1 - 0.052 13.4 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein T4_deiodinase PF00837.17 EGB09353.1 - 0.097 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase SCO1-SenC PF02630.14 EGB09354.1 - 1e-39 135.5 0.0 1.2e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 EGB09354.1 - 0.0036 17.6 0.0 0.0056 17.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGB09354.1 - 0.079 12.9 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family E1_dh PF00676.20 EGB09355.1 - 2.4e-99 332.1 0.4 3e-99 331.8 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGB09355.1 - 0.0064 15.7 0.5 0.0096 15.2 0.1 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EGB09355.1 - 0.0065 16.3 1.7 0.015 15.1 1.7 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glycos_transf_1 PF00534.20 EGB09356.1 - 1.3e-30 106.2 0.0 2.1e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGB09356.1 - 1.5e-27 96.6 0.1 2.6e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGB09356.1 - 5.3e-21 75.4 0.1 3.7e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGB09356.1 - 4e-18 66.4 0.2 5.3e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGB09356.1 - 3.9e-11 43.2 0.0 7.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EGB09356.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like PALP PF00291.25 EGB09356.1 - 0.034 13.6 0.0 0.093 12.1 0.0 1.8 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_hydro_2_C PF02836.17 EGB09357.1 - 3e-63 213.7 0.0 5e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EGB09357.1 - 1.3e-16 60.9 0.0 5e-16 59.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EGB09357.1 - 4.4e-06 27.3 0.0 1.5e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_cc PF11790.8 EGB09357.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.13 EGB09357.1 - 0.12 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 BetaGal_dom4_5 PF13364.6 EGB09357.1 - 0.16 12.6 0.0 0.48 11.0 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Metallophos PF00149.28 EGB09358.1 - 1.4e-10 42.1 0.0 1.3e-09 38.8 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB09358.1 - 1e-07 32.3 0.0 0.00029 21.1 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Maf PF02545.14 EGB09359.1 - 2.7e-26 92.4 0.0 3e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein BppL_N PF18338.1 EGB09359.1 - 0.011 15.5 3.4 0.027 14.2 3.4 1.6 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain DUF58 PF01882.18 EGB09359.1 - 0.044 14.1 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF58 zf-MYND PF01753.18 EGB09360.1 - 8.1e-07 29.0 8.6 1.6e-06 28.1 8.6 1.5 1 0 0 1 1 1 1 MYND finger Methyltransf_23 PF13489.6 EGB09360.1 - 7e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB09360.1 - 0.00032 21.3 0.2 0.00078 20.1 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09360.1 - 0.00056 20.5 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain zf-C6H2 PF15801.5 EGB09360.1 - 0.00063 20.0 7.0 0.0013 19.0 7.0 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Methyltransf_31 PF13847.6 EGB09360.1 - 0.0059 16.4 0.2 0.012 15.4 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB09360.1 - 0.011 16.4 0.0 0.025 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EGB09360.1 - 0.042 13.5 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DZR PF12773.7 EGB09360.1 - 0.12 12.4 5.4 0.36 10.9 5.4 1.8 1 0 0 1 1 1 0 Double zinc ribbon MTS PF05175.14 EGB09360.1 - 0.15 11.6 0.1 0.63 9.6 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain DUF2939 PF11159.8 EGB09362.1 - 0.0036 17.7 0.3 0.019 15.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2939) Stomagen PF16851.5 EGB09362.1 - 0.11 12.6 1.7 0.34 11.0 1.7 1.9 1 0 0 1 1 1 0 Stomagen Ion_trans PF00520.31 EGB09363.1 - 9.6e-34 116.7 21.7 1.2e-22 80.4 5.4 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_8 PF13833.6 EGB09363.1 - 0.00069 19.4 0.1 0.0019 18.0 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB09363.1 - 0.0017 17.8 0.2 0.0051 16.3 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGB09363.1 - 0.0024 17.7 3.0 0.014 15.3 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EGB09363.1 - 0.0025 17.2 0.7 0.014 14.9 0.7 2.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGB09363.1 - 0.0094 16.4 3.7 0.02 15.3 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair YpmT PF17431.2 EGB09363.1 - 0.11 12.5 2.0 1.1 9.4 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized YmpT-like PKD_channel PF08016.12 EGB09363.1 - 0.92 8.1 19.8 0.043 12.5 3.4 3.0 3 0 0 3 3 3 0 Polycystin cation channel 2OG-FeII_Oxy_3 PF13640.6 EGB09364.1 - 4.2e-19 69.2 0.0 5.4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 EGB09365.1 - 6.4e-20 71.4 0.2 6.8e-20 71.4 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB09365.1 - 2e-12 47.2 0.5 2.2e-12 47.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 EGB09366.1 - 1.9e-30 105.3 0.1 6.6e-14 52.3 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09366.1 - 1.5e-16 58.8 0.1 0.00043 20.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB09366.1 - 8.8e-16 57.8 3.9 1e-06 28.8 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB09366.1 - 1.1e-15 57.8 2.0 1.6e-07 31.7 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB09366.1 - 2.2e-13 50.0 2.2 3e-06 27.4 0.1 3.8 4 0 0 4 4 4 3 Ankyrin repeat DUF5336 PF17270.2 EGB09366.1 - 0.21 11.2 0.0 1.4 8.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Metallophos PF00149.28 EGB09367.1 - 5.6e-16 59.7 0.0 8.6e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EGB09367.1 - 3.7e-11 43.7 0.7 7.7e-11 42.7 0.7 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Fcf1 PF04900.12 EGB09368.1 - 3.3e-28 98.0 0.2 3.3e-28 98.0 0.2 1.8 2 1 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EGB09368.1 - 9.1e-15 55.0 0.1 9.1e-15 55.0 0.1 1.6 2 0 0 2 2 2 1 PIN like domain EF-hand_14 PF17959.1 EGB09368.1 - 0.037 14.4 0.1 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain DTC PF18102.1 EGB09369.1 - 7.5e-45 152.3 0.0 8.4e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Deltex C-terminal domain HSF_DNA-bind PF00447.17 EGB09370.1 - 1.7e-29 102.3 0.0 5e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Arf PF00025.21 EGB09371.1 - 6.7e-79 263.4 0.1 7.6e-79 263.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGB09371.1 - 6.1e-15 55.5 0.0 8.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGB09371.1 - 2.2e-13 50.1 0.0 2.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGB09371.1 - 6.5e-13 48.5 0.0 7.7e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGB09371.1 - 6.2e-12 45.3 0.8 7.4e-08 31.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGB09371.1 - 2.7e-09 36.7 0.0 3.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB09371.1 - 1.4e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGB09371.1 - 0.0085 15.4 0.1 0.011 15.1 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase DnaJ PF00226.31 EGB09372.1 - 1.1e-17 63.9 0.0 1.2e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain CS PF04969.16 EGB09374.1 - 3.1e-09 37.7 0.0 0.014 16.4 0.0 3.3 3 0 0 3 3 3 3 CS domain TFIIE-A_C PF11521.8 EGB09374.1 - 3.9 7.8 5.3 7.4 6.9 1.0 2.9 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha GYF_2 PF14237.6 EGB09375.1 - 0.03 14.1 1.2 0.1 12.4 0.1 2.4 2 0 0 2 2 2 0 GYF domain 2 DUF3040 PF11239.8 EGB09375.1 - 0.32 11.3 4.5 0.34 11.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Tubulin PF00091.25 EGB09376.1 - 1e-67 228.2 0.0 1.7e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB09376.1 - 2e-40 137.9 0.1 3e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGB09376.1 - 0.00014 22.2 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGB09376.1 - 0.003 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGB09376.1 - 0.02 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like CMAS PF02353.20 EGB09377.1 - 1.3e-65 221.4 0.0 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGB09377.1 - 5.6e-12 46.2 0.0 1.3e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB09377.1 - 2.4e-09 37.8 0.0 5e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09377.1 - 8.3e-08 32.8 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB09377.1 - 1.4e-06 28.1 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09377.1 - 6.9e-06 26.0 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGB09377.1 - 0.00035 20.1 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EGB09377.1 - 0.00053 19.6 0.1 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.12 EGB09377.1 - 0.011 15.6 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_33 PF10017.9 EGB09377.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent PCMT PF01135.19 EGB09377.1 - 0.24 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CD36 PF01130.21 EGB09378.1 - 1.7e-33 115.9 0.0 1.3e-27 96.4 0.0 2.3 2 0 0 2 2 2 2 CD36 family Glyco_trans_1_2 PF13524.6 EGB09378.1 - 7.3e-10 39.1 0.0 2.2e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 HemY_N PF07219.13 EGB09378.1 - 0.089 13.0 3.0 0.14 12.4 0.3 2.6 2 1 1 3 3 3 0 HemY protein N-terminus Myb_DNA-binding PF00249.31 EGB09380.1 - 5.8e-18 64.8 4.3 5e-10 39.4 0.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB09380.1 - 2.5e-16 59.7 0.2 7.7e-12 45.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EGB09380.1 - 0.04 14.0 0.0 0.22 11.7 0.0 2.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EGB09380.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 SLIDE adh_short PF00106.25 EGB09381.1 - 1e-17 64.2 3.0 2.8e-16 59.6 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase Golgin_A5 PF09787.9 EGB09381.1 - 3.1e-06 26.9 4.8 5.4e-05 22.8 0.0 2.6 1 1 0 2 2 2 1 Golgin subfamily A member 5 Epimerase PF01370.21 EGB09381.1 - 0.00021 20.9 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGB09381.1 - 0.00023 21.2 0.0 0.0006 19.8 0.0 1.7 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 EGB09382.1 - 7.3e-49 166.5 0.0 1.1e-48 166.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09382.1 - 1.1e-31 110.1 0.0 5e-31 107.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09382.1 - 9e-06 25.2 0.0 1.6e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB09382.1 - 0.00018 20.4 0.0 0.00026 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB09382.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB09382.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4457 PF14652.6 EGB09383.1 - 2.6e-123 411.4 0.0 1.2e-53 182.5 0.0 4.5 5 0 0 5 5 5 4 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 EGB09383.1 - 0.0035 17.3 0.0 9.3 6.3 0.0 3.7 5 0 0 5 5 5 2 Sad1 / UNC-like C-terminal NeA_P2 PF12312.8 EGB09383.1 - 0.093 12.2 0.8 2.8 7.3 0.3 2.4 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Acyl_transf_3 PF01757.22 EGB09384.1 - 8e-19 67.9 17.9 1.4e-18 67.1 17.9 1.3 1 0 0 1 1 1 1 Acyltransferase family Ion_trans PF00520.31 EGB09385.1 - 3.3e-20 72.4 7.9 5.5e-20 71.6 7.9 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB09385.1 - 3e-06 27.2 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cyclin_N PF00134.23 EGB09385.1 - 0.00075 19.2 0.1 0.0027 17.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ion_trans_2 PF07885.16 EGB09385.1 - 0.0049 16.8 0.6 0.017 15.1 0.6 1.9 1 0 0 1 1 1 1 Ion channel FMN_dh PF01070.18 EGB09386.1 - 1.9e-108 362.6 0.4 2.8e-108 362.0 0.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGB09386.1 - 3.4e-16 59.1 0.0 6.8e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGB09386.1 - 2.8e-11 43.2 1.0 4.7e-11 42.4 1.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGB09386.1 - 0.00011 21.3 0.4 0.00022 20.3 0.4 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EGB09386.1 - 0.02 14.3 0.1 0.054 13.0 0.0 1.7 1 1 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 EGB09386.1 - 0.038 13.3 0.5 5.8 6.2 0.0 2.5 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG RRM_1 PF00076.22 EGB09387.1 - 7.6e-17 60.9 0.2 9.2e-17 60.6 0.2 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 EGB09387.1 - 0.04 13.5 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated TPT PF03151.16 EGB09388.1 - 4.5e-10 39.4 1.4 5.5e-10 39.1 1.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EGB09388.1 - 1.4e-06 27.8 0.3 1.8e-06 27.4 0.3 1.1 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EGB09388.1 - 0.00088 18.6 6.9 0.0014 17.9 6.9 1.2 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 EGB09388.1 - 0.0017 18.6 16.2 0.077 13.2 3.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3464 PF11947.8 EGB09388.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 ArfGap PF01412.18 EGB09389.1 - 3.6e-20 72.2 1.4 3.8e-20 72.1 1.4 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-RRN7 PF11781.8 EGB09389.1 - 0.00025 20.6 1.1 0.00033 20.3 1.1 1.2 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf_UBZ PF18439.1 EGB09389.1 - 0.042 13.4 0.2 5 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 EGB09389.1 - 0.076 13.1 0.6 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EGB09389.1 - 0.087 12.4 3.9 2.6 7.6 4.5 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding zf-dskA_traR PF01258.17 EGB09389.1 - 0.1 12.6 2.9 7.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Rad51 PF08423.11 EGB09390.1 - 2.2e-07 30.4 0.0 3.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EGB09390.1 - 2.1e-05 24.2 0.5 4.9e-05 23.0 0.5 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB09390.1 - 0.046 14.1 0.3 0.17 12.3 0.3 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC1 PF03109.16 EGB09391.1 - 2e-22 79.6 0.0 3.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGB09391.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SGL PF08450.12 EGB09392.1 - 1.8e-05 24.5 0.1 0.0012 18.5 0.1 2.4 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EGB09392.1 - 2.3e-05 24.2 12.8 0.75 9.9 0.0 5.8 6 0 0 6 6 6 4 NHL repeat Str_synth PF03088.16 EGB09392.1 - 0.16 12.1 0.0 28 4.9 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase DUF5122 PF17164.4 EGB09392.1 - 2.2 8.7 4.7 1.7 9.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Lactamase_B_2 PF12706.7 EGB09393.1 - 4.7e-12 45.8 0.5 6.1e-12 45.5 0.5 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGB09393.1 - 0.0026 17.8 3.5 0.0061 16.6 3.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGB09393.1 - 0.19 11.1 0.2 1.5 8.2 0.1 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain DCP2 PF05026.13 EGB09394.1 - 7.5e-25 87.1 0.1 1.2e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EGB09394.1 - 1.5e-11 44.4 0.0 2.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SERTA PF06031.13 EGB09394.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 SERTA motif EPL1 PF10513.9 EGB09394.1 - 0.18 12.2 0.0 0.2 12.1 0.0 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like GST_C_2 PF13410.6 EGB09395.1 - 5.1e-08 32.8 0.0 1.6e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB09395.1 - 6.6e-08 32.9 0.0 1.4e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB09395.1 - 7.9e-07 29.2 0.2 7.9e-07 29.2 0.2 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGB09395.1 - 9.8e-06 25.8 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGB09395.1 - 0.00024 21.2 3.4 0.00038 20.6 0.8 2.5 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGB09395.1 - 0.00099 19.8 0.1 0.0043 17.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 EGB09395.1 - 0.003 17.9 0.0 0.008 16.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ECH_2 PF16113.5 EGB09395.1 - 0.05 13.1 0.1 0.072 12.6 0.1 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase GST_C_6 PF17171.4 EGB09395.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EGB09395.1 - 0.086 12.7 0.9 8.5 6.2 0.4 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain Tcf25 PF04910.14 EGB09395.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Peptidase_C97 PF05903.14 EGB09396.1 - 2.1e-26 92.5 0.0 2.3e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Cyclin_N PF00134.23 EGB09397.1 - 3.5e-09 36.5 0.5 3.9e-09 36.3 0.5 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGB09397.1 - 4.2e-06 27.2 0.1 5.1e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Cyclin WW PF00397.26 EGB09399.1 - 7.5e-16 57.9 13.7 5.8e-08 32.7 3.5 2.8 2 0 0 2 2 2 2 WW domain Ank_2 PF12796.7 EGB09400.1 - 7.6e-69 228.3 22.7 1.4e-10 41.6 0.1 12.0 5 1 10 15 15 15 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB09400.1 - 1.2e-49 166.1 27.9 7e-09 36.1 0.0 16.1 11 7 4 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB09400.1 - 3.5e-39 132.3 59.6 4.9e-07 29.9 0.1 17.4 10 6 8 18 18 18 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB09400.1 - 4.3e-39 128.1 35.9 0.0032 17.8 0.0 20.0 22 0 0 22 22 22 10 Ankyrin repeat Ank PF00023.30 EGB09400.1 - 3.3e-26 90.5 57.3 0.00077 19.8 0.0 17.3 19 0 0 19 19 19 9 Ankyrin repeat YqaH PF17448.2 EGB09400.1 - 0.0045 17.3 0.3 2.6 8.4 0.1 2.7 2 0 0 2 2 2 2 Uncharacterized YqaH-like EGF_2 PF07974.13 EGB09401.1 - 3.8e-15 56.0 56.0 4.2e-06 27.0 6.2 5.3 4 1 0 4 4 4 4 EGF-like domain Laminin_EGF PF00053.24 EGB09401.1 - 0.014 15.5 19.3 0.028 14.6 6.8 4.6 2 2 2 4 4 4 0 Laminin EGF domain EGF PF00008.27 EGB09401.1 - 0.042 14.1 45.5 0.1 12.9 2.3 6.1 5 1 1 6 6 6 0 EGF-like domain Herpes_UL92 PF03048.14 EGB09401.1 - 0.62 9.8 4.7 1.1 9.1 4.7 1.4 1 0 0 1 1 1 0 UL92 family EGF_Tenascin PF18720.1 EGB09401.1 - 1.7 8.7 55.4 0.53 10.4 0.5 5.6 5 0 0 5 5 5 0 Tenascin EGF domain GILT PF03227.16 EGB09402.1 - 3.9e-14 52.8 0.0 1.3e-12 47.8 0.0 2.4 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PEMT PF04191.13 EGB09403.1 - 6.4e-05 23.3 0.1 0.00011 22.6 0.1 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 EGB09403.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 EGB09403.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Sulfatase PF00884.23 EGB09404.1 - 2.6e-18 66.5 0.0 2.9e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Sulfatase WES_acyltransf PF03007.16 EGB09405.1 - 1.2e-10 41.6 4.9 2.4e-10 40.6 4.9 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 EGB09405.1 - 2.6e-10 40.4 0.0 5.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 EGB09405.1 - 0.044 12.5 0.0 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Condensation domain DUF4573 PF15140.6 EGB09406.1 - 0.031 14.1 1.3 0.06 13.1 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) 2OG-FeII_Oxy PF03171.20 EGB09406.1 - 0.046 14.2 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily His_Phos_1 PF00300.22 EGB09407.1 - 9.4e-20 71.1 0.0 2.7e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_32N PF00251.20 EGB09408.1 - 1.1e-34 120.4 0.0 1.2e-34 120.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Exc PF07825.11 EGB09408.1 - 0.14 12.1 1.5 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Excisionase-like protein PT PF04886.12 EGB09409.1 - 1.6e-06 27.5 73.5 2.8e-05 23.6 15.9 4.9 1 1 2 3 3 3 2 PT repeat Ysc84 PF04366.12 EGB09410.1 - 4.5e-27 94.3 0.2 1e-26 93.2 0.0 1.7 2 0 0 2 2 2 1 Las17-binding protein actin regulator FYVE PF01363.21 EGB09410.1 - 6.3e-16 58.3 5.4 1.8e-15 56.8 5.4 1.8 1 0 0 1 1 1 1 FYVE zinc finger TPR_4 PF07721.14 EGB09410.1 - 0.038 14.6 16.2 0.29 11.9 2.9 5.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_Rpc4 PF05132.14 EGB09410.1 - 0.15 12.5 1.1 0.48 10.8 1.1 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_polI_A34 PF08208.11 EGB09410.1 - 0.34 11.0 5.9 0.68 10.0 5.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Trypan_PARP PF05887.11 EGB09410.1 - 1.4 8.9 6.6 0.33 10.9 0.5 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) IBR PF01485.21 EGB09410.1 - 2 8.7 4.3 5.6 7.3 4.3 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF572 PF04502.13 EGB09411.1 - 2.4e-57 195.1 3.9 3.2e-57 194.6 3.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-dskA_traR PF01258.17 EGB09411.1 - 0.032 14.2 2.2 0.037 14.0 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger TF_Zn_Ribbon PF08271.12 EGB09411.1 - 0.077 12.5 5.1 2.6 7.6 2.4 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding PK PF00224.21 EGB09412.1 - 6.1e-134 446.3 0.1 7.9e-134 445.9 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGB09412.1 - 2e-14 53.8 2.0 6.5e-14 52.2 2.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGB09412.1 - 0.00085 18.5 0.6 0.00085 18.5 0.6 2.3 2 1 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family PA PF02225.22 EGB09412.1 - 1.6 8.8 6.5 9.6 6.3 6.5 2.3 1 1 0 1 1 1 0 PA domain SASA PF03629.18 EGB09413.1 - 1.8e-54 184.8 0.0 2.1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase DUF3464 PF11947.8 EGB09414.1 - 7.2e-31 107.0 0.0 1.9e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 WW PF00397.26 EGB09414.1 - 1.9e-09 37.4 0.3 3.8e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 WW domain Abhydrolase_2 PF02230.16 EGB09414.1 - 0.00012 21.9 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase SAP PF02037.27 EGB09414.1 - 0.0049 16.6 0.2 1.2 9.0 0.1 2.5 2 0 0 2 2 2 2 SAP domain Armet PF10208.9 EGB09414.1 - 0.0081 16.1 0.1 0.023 14.6 0.0 1.6 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding DLH PF01738.18 EGB09414.1 - 0.016 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Endonuclease_1 PF04231.13 EGB09415.1 - 1.8e-27 96.6 0.0 2.5e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease I Pkinase PF00069.25 EGB09416.1 - 6.2e-58 196.2 0.0 7.3e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09416.1 - 2.4e-51 174.5 0.0 2.7e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB09416.1 - 1.5e-06 27.3 0.0 2.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB09416.1 - 3.4e-05 23.3 0.0 0.00021 20.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 EGB09416.1 - 0.01 16.0 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 EGB09416.1 - 0.011 15.7 1.4 0.53 10.2 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EGB09416.1 - 0.023 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB09416.1 - 0.15 11.0 0.0 2.6 6.9 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain UQ_con PF00179.26 EGB09417.1 - 1.2e-25 89.8 0.0 1.4e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGB09417.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 UEV domain UFC1 PF08694.11 EGB09417.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Band_7 PF01145.25 EGB09418.1 - 9.7e-22 77.8 5.4 1.5e-21 77.2 4.3 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGB09418.1 - 3.9e-05 22.9 2.6 6.6e-05 22.1 2.6 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial Med2 PF11214.8 EGB09418.1 - 0.0022 18.1 1.0 0.0036 17.4 1.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 2 DUF45 PF01863.17 EGB09418.1 - 0.22 11.5 1.6 0.46 10.5 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF45 PHM7_cyt PF14703.6 EGB09419.1 - 0.0098 16.1 0.0 0.11 12.7 0.0 2.4 1 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EGB09419.1 - 0.025 13.4 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel RSN1_7TM PF02714.15 EGB09419.1 - 0.052 12.8 0.3 1.5 8.1 0.3 2.2 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate NAD_binding_1 PF00175.21 EGB09420.1 - 2.5e-34 118.2 0.0 7.6e-34 116.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGB09420.1 - 6e-25 87.5 0.0 1.3e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGB09420.1 - 0.00041 20.5 0.0 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EGB09420.1 - 0.027 14.7 0.0 0.077 13.2 0.0 1.7 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain Corona_NS1 PF06145.11 EGB09420.1 - 0.24 11.0 2.0 8.5 6.0 0.2 2.4 2 0 0 2 2 2 0 Coronavirus nonstructural protein NS1 Dockerin_1 PF00404.18 EGB09421.1 - 0.12 12.5 0.3 0.25 11.6 0.3 1.4 1 0 0 1 1 1 0 Dockerin type I domain MTP18 PF10558.9 EGB09423.1 - 6.3e-14 52.3 1.7 1.2e-06 28.6 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Gar1 PF04410.14 EGB09424.1 - 6.5e-32 110.4 0.0 8.3e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DEAD PF00270.29 EGB09427.1 - 2.8e-49 167.3 0.0 4.5e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB09427.1 - 4.8e-22 78.4 0.0 1.1e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB09427.1 - 0.016 15.2 0.0 0.039 14.0 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sulfatase PF00884.23 EGB09428.1 - 3.6e-57 194.1 0.1 5.4e-57 193.5 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Ank_2 PF12796.7 EGB09428.1 - 1.2e-20 73.9 0.0 6e-11 42.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09428.1 - 2.7e-09 36.5 0.0 0.0012 19.1 0.0 3.6 3 0 0 3 3 2 2 Ankyrin repeat Ank PF00023.30 EGB09428.1 - 5.8e-07 29.7 0.0 0.0033 17.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGB09428.1 - 1.9e-06 28.3 0.0 1.7e-05 25.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB09428.1 - 3e-06 27.4 0.2 0.00045 20.5 0.1 3.1 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Glyco_transf_8 PF01501.20 EGB09428.1 - 8e-06 25.6 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Gly_transf_sug PF04488.15 EGB09428.1 - 1.8e-05 25.3 0.0 5.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Sulfatase_C PF14707.6 EGB09428.1 - 0.00011 23.0 0.0 0.0003 21.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Caps_synth PF05704.12 EGB09428.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF4994 PF16385.5 EGB09428.1 - 0.15 12.0 0.0 0.86 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function MFS_1 PF07690.16 EGB09429.1 - 3.8e-36 124.7 59.4 2.7e-35 121.9 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGB09429.1 - 1.6e-07 30.9 4.3 1.6e-07 30.9 4.3 2.7 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EGB09429.1 - 9.2e-07 28.1 2.9 9.2e-07 28.1 2.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGB09429.1 - 1.2e-05 24.3 2.4 0.0002 20.3 0.8 2.7 2 1 1 3 3 3 2 MFS_1 like family Pam17 PF08566.10 EGB09429.1 - 0.34 10.7 3.9 5.4 6.8 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 Pkinase PF00069.25 EGB09430.1 - 4.4e-57 193.4 0.0 9.2e-57 192.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09430.1 - 2.7e-25 89.1 0.0 3.2e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB09430.1 - 0.00015 21.2 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB09430.1 - 0.00043 19.2 0.0 0.00053 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB09430.1 - 0.004 16.5 0.0 0.0057 16.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB09430.1 - 0.032 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGB09430.1 - 0.089 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PAP2 PF01569.21 EGB09431.1 - 1.3e-13 50.9 11.1 1.8e-13 50.4 5.2 2.5 2 1 0 2 2 2 1 PAP2 superfamily DEAD PF00270.29 EGB09432.1 - 0.093 12.5 0.1 0.11 12.2 0.1 1.0 1 0 0 1 1 1 0 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EGB09433.1 - 1.2e-19 70.4 0.0 1.9e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGB09433.1 - 4.9e-15 55.8 0.4 9.5e-15 54.8 0.1 1.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) MFS_1_like PF12832.7 EGB09434.1 - 9.8e-43 146.5 0.0 1.3e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGB09434.1 - 6.4e-12 45.1 29.7 3.8e-11 42.5 21.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EGB09434.1 - 0.0013 17.8 1.8 0.0013 17.8 1.8 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 EGB09434.1 - 0.055 12.2 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 LacY proton/sugar symporter FKBP_C PF00254.28 EGB09435.1 - 3.5e-31 107.4 0.0 4.3e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DnaJ PF00226.31 EGB09436.1 - 1.7e-19 69.7 0.6 2.8e-19 69.0 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2523 PF10734.9 EGB09436.1 - 4 8.1 8.6 6.9 7.3 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) IcmF-related PF06761.12 EGB09438.1 - 0.0021 17.6 0.1 0.0046 16.5 0.0 1.5 2 0 0 2 2 2 1 Intracellular multiplication and human macrophage-killing DUF4129 PF13559.6 EGB09438.1 - 0.33 11.2 3.0 0.3 11.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Pkinase PF00069.25 EGB09439.1 - 8.4e-30 104.0 0.0 9e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09439.1 - 1.2e-08 34.6 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09439.1 - 0.0027 17.1 0.0 0.0029 17.0 0.0 1.0 1 0 0 1 1 1 1 Kinase-like DUF3449 PF11931.8 EGB09440.1 - 3.2e-72 242.2 0.3 4.1e-72 241.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 EGB09440.1 - 2.7e-21 75.0 0.5 5.3e-21 74.0 0.5 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 EGB09440.1 - 8.8e-20 71.0 0.0 1.6e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EGB09440.1 - 0.019 14.8 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain IclR PF01614.18 EGB09440.1 - 0.07 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Bacterial transcriptional regulator WD40 PF00400.32 EGB09441.1 - 4.4e-08 33.7 1.5 0.024 15.5 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGB09441.1 - 0.0045 17.0 0.0 0.21 11.7 0.0 2.9 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 EGB09441.1 - 0.0046 17.2 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EGB09441.1 - 0.0054 16.6 0.3 0.041 13.8 0.1 2.6 3 0 0 3 3 3 1 PQQ enzyme repeat WD40 PF00400.32 EGB09442.1 - 2.4e-43 145.3 16.7 2.3e-07 31.4 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09442.1 - 6.6e-10 39.1 0.0 0.056 13.7 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB09442.1 - 6e-08 32.0 0.3 0.03 13.3 0.0 3.4 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 EGB09442.1 - 0.00045 20.6 6.6 2.3 8.8 0.0 4.7 5 2 0 5 5 5 2 PQQ-like domain Cytochrom_D1 PF02239.16 EGB09442.1 - 0.0023 16.5 0.1 0.35 9.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EGB09442.1 - 0.011 15.1 0.0 0.12 11.7 0.0 2.5 2 2 1 3 3 3 0 WD40-like domain Frtz PF11768.8 EGB09442.1 - 0.043 12.1 0.0 1.6 6.9 0.0 2.6 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 EGB09442.1 - 0.094 11.3 0.1 6.1 5.4 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 EGB09442.1 - 0.84 9.7 0.0 0.84 9.7 0.0 4.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Clat_adaptor_s PF01217.20 EGB09443.1 - 1.5e-45 154.6 1.0 1.7e-45 154.4 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Asp PF00026.23 EGB09444.1 - 1.2e-63 215.4 0.1 1.4e-63 215.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGB09444.1 - 1.3e-15 58.1 0.0 5.8e-08 33.2 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGB09444.1 - 3.9e-06 26.7 0.0 1.9e-05 24.5 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGB09444.1 - 0.1 13.2 0.0 3.8 8.1 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease ROK PF00480.20 EGB09445.1 - 3.4e-47 161.3 0.0 4.5e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 ROK family DnaJ PF00226.31 EGB09446.1 - 4.9e-20 71.4 0.0 5.6e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain PARP PF00644.20 EGB09447.1 - 3.2e-28 98.6 0.0 8e-28 97.4 0.0 1.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain TauD PF02668.16 EGB09447.1 - 2e-25 90.1 0.1 4.1e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WWE PF02825.20 EGB09447.1 - 3.2e-09 37.2 0.6 1e-08 35.6 0.6 1.9 1 0 0 1 1 1 1 WWE domain NMT1 PF09084.11 EGB09447.1 - 1.5e-08 34.9 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like CUB PF00431.20 EGB09447.1 - 1.6e-07 31.6 0.0 0.0029 17.9 0.0 3.5 3 0 0 3 3 3 2 CUB domain Phosphonate-bd PF12974.7 EGB09447.1 - 0.0035 17.0 0.4 0.0075 15.9 0.4 1.5 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SH3_9 PF14604.6 EGB09447.1 - 0.017 15.0 0.0 0.064 13.1 0.0 2.0 1 0 0 1 1 1 0 Variant SH3 domain Thioredoxin PF00085.20 EGB09448.1 - 2.2e-21 75.8 0.0 2.4e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EGB09448.1 - 9.5e-05 22.3 0.0 9.9e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EGB09448.1 - 9.7e-05 22.3 0.0 0.00011 22.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 EGB09448.1 - 0.00013 22.3 0.2 0.0011 19.4 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGB09448.1 - 0.0012 19.1 0.0 0.94 9.8 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EGB09448.1 - 0.0056 16.8 0.0 0.0086 16.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 EGB09448.1 - 0.052 13.5 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 EGB09448.1 - 0.07 12.8 0.0 9 5.9 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin mTERF PF02536.14 EGB09449.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 mTERF PGK PF00162.19 EGB09450.1 - 2.8e-155 516.9 0.1 3.7e-155 516.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PhyH PF05721.13 EGB09450.1 - 3e-10 40.7 0.0 1e-09 39.0 0.0 1.9 3 0 0 3 3 3 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3638 PF12340.8 EGB09452.1 - 4.1e-27 95.0 0.0 1.4e-26 93.2 0.0 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGB09452.1 - 8.4e-15 53.9 0.2 2.2e-14 52.5 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Thioredoxin PF00085.20 EGB09452.1 - 1.4e-13 50.7 0.1 1.8e-06 27.8 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin WWE PF02825.20 EGB09452.1 - 0.00038 21.0 0.1 0.81 10.3 0.4 2.6 2 0 0 2 2 2 2 WWE domain Laminin_G_3 PF13385.6 EGB09452.1 - 0.0008 19.6 0.0 0.006 16.7 0.0 2.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily FG-GAP_2 PF14312.6 EGB09453.1 - 7.9e-139 451.8 90.5 1.8e-22 79.3 5.3 8.7 8 0 0 8 8 8 7 FG-GAP repeat BNR_2 PF13088.6 EGB09453.1 - 5.6e-06 25.8 0.7 0.011 15.0 0.1 2.7 1 1 0 2 2 2 2 BNR repeat-like domain PQQ_3 PF13570.6 EGB09453.1 - 2.1e-05 24.9 47.6 2.1 9.0 0.7 9.3 9 0 0 9 9 9 7 PQQ-like domain Lectin_leg-like PF03388.13 EGB09453.1 - 0.00029 20.3 1.3 16 4.7 0.0 4.2 3 1 1 4 4 4 3 Legume-like lectin family XPG_I_2 PF12813.7 EGB09453.1 - 0.0033 16.9 0.1 0.006 16.1 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing DUF3804 PF12707.7 EGB09454.1 - 9.6e-35 119.1 0.0 1.1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3804) SnoaL_3 PF13474.6 EGB09454.1 - 0.00028 21.1 0.0 0.00041 20.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGB09454.1 - 0.0014 19.0 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Ribosomal_S8 PF00410.19 EGB09455.1 - 6.2e-22 77.9 0.0 1.1e-21 77.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 SET PF00856.28 EGB09458.1 - 1.6e-10 41.6 0.0 5.5e-10 39.9 0.0 1.9 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EGB09458.1 - 4.9e-09 36.1 8.8 4.9e-09 36.1 8.8 2.4 2 0 0 2 2 2 1 MYND finger CRAL_TRIO PF00650.20 EGB09458.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain PAE PF03283.13 EGB09460.1 - 1.2e-61 208.8 0.0 1.6e-61 208.4 0.0 1.2 1 0 0 1 1 1 1 Pectinacetylesterase DUF3325 PF11804.8 EGB09460.1 - 0.0036 17.4 0.4 0.0066 16.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3325) MRP-S35 PF10246.9 EGB09460.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 ATP-synt_ab PF00006.25 EGB09461.1 - 2.4e-66 223.5 0.0 3.2e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGB09461.1 - 1.9e-10 41.1 0.2 3.6e-10 40.2 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_S28 PF05577.12 EGB09462.1 - 4.7e-54 183.8 0.0 1.3e-53 182.4 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 EGB09462.1 - 0.0041 16.4 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB09462.1 - 0.037 13.7 0.1 0.067 12.8 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioredoxin_8 PF13905.6 EGB09463.1 - 2.1e-21 76.0 0.0 3.2e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like fn3 PF00041.21 EGB09463.1 - 1.2e-08 35.2 0.0 2.9e-06 27.5 0.0 2.8 2 1 0 2 2 2 1 Fibronectin type III domain Thioredoxin PF00085.20 EGB09463.1 - 3.8e-05 23.6 0.0 0.0089 16.0 0.0 2.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB09463.1 - 9.5e-05 22.8 0.0 0.00022 21.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EGB09463.1 - 0.00037 20.2 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGB09463.1 - 0.00041 20.3 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EGB09463.1 - 0.002 18.2 0.0 0.012 15.8 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Tissue_fac PF01108.17 EGB09463.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Tissue factor GPI-anchored PF10342.9 EGB09463.1 - 0.088 13.6 0.0 0.58 10.9 0.0 2.3 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CDP-OH_P_transf PF01066.21 EGB09464.1 - 6.1e-12 46.1 0.5 6.1e-12 46.1 0.5 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peripla_BP_2 PF01497.18 EGB09465.1 - 0.0062 16.1 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein TMEM154 PF15102.6 EGB09465.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family CD34_antigen PF06365.12 EGB09465.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family ABC2_membrane PF01061.24 EGB09467.1 - 7.2e-24 84.4 5.4 9.6e-24 84.0 5.4 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGB09467.1 - 1.1e-18 68.0 0.0 1.7e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB09467.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGB09467.1 - 1.7e-05 25.2 0.4 2.9e-05 24.5 0.4 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGB09467.1 - 0.00066 19.4 0.0 0.0065 16.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB09467.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGB09467.1 - 0.0021 18.3 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB09467.1 - 0.0035 17.9 0.0 0.0055 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB09467.1 - 0.004 16.9 0.1 0.0074 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGB09467.1 - 0.0058 16.5 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGB09467.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EGB09467.1 - 0.015 14.9 0.4 0.026 14.1 0.4 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGB09467.1 - 0.017 14.7 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGB09467.1 - 0.032 14.4 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB09467.1 - 0.038 14.5 0.0 0.058 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB09467.1 - 0.061 13.0 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB09467.1 - 0.063 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGB09467.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EGB09467.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 EGB09467.1 - 0.12 11.3 0.7 0.21 10.6 0.7 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 EGB09467.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 EGB09467.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGB09467.1 - 0.26 11.1 0.1 0.39 10.5 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EGB09467.1 - 0.29 11.2 0.0 0.42 10.7 0.0 1.2 1 0 0 1 1 1 0 Dynamin family FAD_binding_7 PF03441.14 EGB09468.1 - 0.034 13.6 0.2 0.04 13.4 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase YHS PF04945.13 EGB09469.1 - 9.8e-05 22.4 0.3 0.00023 21.2 0.3 1.5 1 0 0 1 1 1 1 YHS domain GPP34 PF05719.11 EGB09469.1 - 0.00092 19.3 1.8 0.0015 18.6 1.8 1.3 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) THF_DHG_CYH_C PF02882.19 EGB09470.1 - 3.6e-64 214.9 2.5 6.1e-64 214.2 2.5 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGB09470.1 - 1.9e-34 118.4 0.0 2.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EGB09470.1 - 0.00016 20.7 0.9 0.00033 19.7 0.9 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Nepo_coat_N PF03689.15 EGB09470.1 - 0.038 13.9 0.0 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain UCH PF00443.29 EGB09471.1 - 1.4e-13 51.0 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GreA_GreB_N PF03449.15 EGB09472.1 - 0.1 12.8 0.2 0.1 12.8 0.2 5.3 5 1 0 5 5 5 0 Transcription elongation factor, N-terminal KASH_CCD PF14662.6 EGB09472.1 - 0.16 11.8 44.4 0.29 10.9 6.7 3.5 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 EGB09472.1 - 3.1 8.3 14.3 36 4.9 0.0 5.6 5 1 2 7 7 7 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 EGB09472.1 - 6.4 7.5 30.5 0.47 11.1 1.1 7.0 4 1 2 6 6 6 0 SlyX DEAD PF00270.29 EGB09473.1 - 2e-18 66.7 0.0 2.3e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Na_Ca_ex PF01699.24 EGB09476.1 - 6.1e-19 68.5 1.0 6.5e-19 68.4 1.0 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Sulf_transp PF04143.14 EGB09476.1 - 0.017 14.7 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Sulphur transport ECH_2 PF16113.5 EGB09477.1 - 9.1e-44 150.3 0.1 1e-43 150.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGB09477.1 - 4.8e-21 75.2 0.0 5.8e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NIF PF03031.18 EGB09478.1 - 7.1e-42 142.8 0.1 9.6e-42 142.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Methyltransf_25 PF13649.6 EGB09479.1 - 2.9e-18 66.3 0.1 2.6e-17 63.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09479.1 - 9.9e-16 58.0 0.0 2.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FHA PF00498.26 EGB09479.1 - 1.8e-15 57.0 0.6 6e-15 55.3 0.4 2.0 2 0 0 2 2 2 1 FHA domain PH PF00169.29 EGB09479.1 - 8.7e-15 55.1 0.1 4.3e-08 33.6 0.1 2.5 2 0 0 2 2 2 2 PH domain Methyltransf_31 PF13847.6 EGB09479.1 - 1.9e-13 50.5 0.0 6.3e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB09479.1 - 2e-13 50.9 0.0 8.1e-13 49.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09479.1 - 6.5e-13 49.2 0.0 2.2e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Yop-YscD_cpl PF16697.5 EGB09479.1 - 7.5e-09 35.8 0.4 1.8e-08 34.6 0.4 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MTS PF05175.14 EGB09479.1 - 5.5e-06 26.0 0.0 3.8e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGB09479.1 - 0.00036 20.0 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGB09479.1 - 0.00036 20.0 0.0 0.00079 18.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 EGB09479.1 - 0.0015 18.6 0.1 0.006 16.7 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 EGB09479.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TrkA_N PF02254.18 EGB09479.1 - 0.028 14.7 0.1 1.8 8.8 0.0 3.3 3 0 0 3 3 3 0 TrkA-N domain Met_10 PF02475.16 EGB09479.1 - 0.039 13.7 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_2 PF00891.18 EGB09479.1 - 0.054 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain RGS PF00615.19 EGB09479.1 - 0.057 13.7 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Regulator of G protein signaling domain PH_13 PF16652.5 EGB09479.1 - 0.059 13.2 0.2 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Methyltransf_32 PF13679.6 EGB09479.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EGB09479.1 - 0.083 12.5 0.0 0.65 9.5 0.0 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PrmA PF06325.13 EGB09479.1 - 0.087 12.2 0.9 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EGB09479.1 - 0.12 12.3 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_29 PF03141.16 EGB09479.1 - 0.15 10.6 0.0 0.28 9.7 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Glyco_hydro_35 PF01301.19 EGB09480.1 - 8.5e-34 117.6 0.2 1e-33 117.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EGB09480.1 - 1e-07 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Beta-galactosidase Sulfotransfer_2 PF03567.14 EGB09481.1 - 3.8e-30 105.6 0.0 5.1e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family DoxX_2 PF13564.6 EGB09481.1 - 0.21 11.7 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 DoxX-like family GSHPx PF00255.19 EGB09482.1 - 1.4e-25 89.0 0.0 1.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Peptidase_S28 PF05577.12 EGB09483.1 - 4.2e-30 104.9 0.0 6.7e-30 104.2 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EGB09483.1 - 1.9e-05 24.5 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB09483.1 - 8.6e-05 21.9 0.0 0.00013 21.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 EGB09483.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 PS-10 peptidase S37 FIST PF08495.10 EGB09483.1 - 0.087 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 FIST N domain Rib_5-P_isom_A PF06026.14 EGB09484.1 - 5.7e-64 214.9 0.0 6.8e-64 214.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Bactofilin PF04519.13 EGB09485.1 - 8.7e-20 70.8 0.3 1.2e-19 70.4 0.3 1.2 1 0 0 1 1 1 1 Polymer-forming cytoskeletal HA PF03457.14 EGB09485.1 - 1.2e-06 28.7 0.0 2.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain CS PF04969.16 EGB09486.1 - 8.6e-11 42.7 0.0 1.5e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 CS domain Mtc PF03820.17 EGB09487.1 - 5.8e-71 239.1 0.0 6.5e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Glycos_transf_2 PF00535.26 EGB09488.1 - 2.1e-08 34.2 0.1 2.2e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB09488.1 - 2.9e-07 30.6 0.2 3.3e-07 30.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGB09488.1 - 0.028 13.9 0.2 0.035 13.6 0.2 1.3 1 1 0 1 1 1 0 Glycosyl transferase family 21 SNF2_N PF00176.23 EGB09489.1 - 5.7e-64 216.0 0.0 8.7e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB09489.1 - 1.6e-16 60.6 0.0 3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-met2 PF12907.7 EGB09489.1 - 5.9e-11 42.3 1.4 1.1e-10 41.5 1.4 1.5 1 0 0 1 1 1 1 Zinc-binding ResIII PF04851.15 EGB09489.1 - 3.5e-10 40.2 0.0 6.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGB09489.1 - 0.0012 18.1 0.0 0.0032 16.7 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 TUDOR PF00567.24 EGB09490.1 - 0.00077 19.5 0.3 0.0035 17.4 0.0 2.0 2 1 0 2 2 2 1 Tudor domain SMN PF06003.12 EGB09490.1 - 0.0021 17.4 0.5 0.0064 15.8 0.0 1.8 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) MNR PF15718.5 EGB09490.1 - 0.028 12.6 0.2 0.041 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein moonraker Fis1_TPR_C PF14853.6 EGB09490.1 - 0.035 14.2 0.6 0.068 13.2 0.6 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF936 PF06075.12 EGB09490.1 - 0.14 11.0 3.6 0.11 11.3 0.2 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) NTS_2 PF15448.6 EGB09490.1 - 0.15 12.5 0.6 0.99 9.8 0.0 2.4 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein NAD_binding_8 PF13450.6 EGB09491.1 - 3.4e-15 56.0 12.0 7.1e-10 39.0 1.0 4.0 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGB09491.1 - 7.4e-07 28.8 19.1 0.25 10.6 2.9 5.9 3 2 2 5 5 5 5 Flavin containing amine oxidoreductase Thi4 PF01946.17 EGB09491.1 - 0.17 11.1 0.1 0.39 9.9 0.1 1.6 1 0 0 1 1 1 0 Thi4 family TPR_16 PF13432.6 EGB09492.1 - 6.2e-05 23.6 5.8 6.2e-05 23.6 5.8 7.7 6 3 1 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB09492.1 - 8.3e-05 22.4 21.0 0.31 11.3 0.3 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB09492.1 - 0.00025 21.1 2.1 0.00025 21.1 2.1 4.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09492.1 - 0.0021 18.1 11.1 1.2 9.5 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB09492.1 - 0.016 14.9 4.6 1.5 8.6 1.6 3.2 2 1 1 3 3 3 0 TPR repeat TPR_1 PF00515.28 EGB09492.1 - 0.018 14.8 14.4 4.3 7.3 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09492.1 - 0.021 15.3 2.1 0.021 15.3 2.1 4.5 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09492.1 - 0.25 11.6 24.7 0.04 14.2 8.1 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB09492.1 - 1.6 9.5 21.5 0.45 11.3 0.2 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Aminotran_5 PF00266.19 EGB09493.1 - 6.5e-05 22.1 0.0 0.00015 20.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V ABC_tran PF00005.27 EGB09494.1 - 4e-31 108.3 0.0 6.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGB09494.1 - 2.3e-23 83.2 0.0 3.6e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGB09494.1 - 3.8e-06 26.5 0.0 1.2e-05 24.8 0.0 1.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB09494.1 - 0.03 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGB09494.1 - 0.18 12.1 0.1 0.95 9.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain Sel1 PF08238.12 EGB09495.1 - 1.3e-38 130.5 19.7 8.2e-08 32.7 0.1 8.0 7 2 0 7 7 7 7 Sel1 repeat TPR_12 PF13424.6 EGB09495.1 - 1.6e-05 25.1 11.4 0.03 14.6 0.4 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGB09495.1 - 0.00027 20.7 2.1 0.017 15.0 0.3 4.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09495.1 - 0.00083 20.0 10.0 0.29 11.8 0.4 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09495.1 - 0.019 14.8 0.3 0.019 14.8 0.3 6.0 8 1 0 8 8 8 0 Tetratricopeptide repeat 3D PF06725.11 EGB09495.1 - 0.069 13.3 0.1 10 6.4 0.0 2.8 2 1 1 3 3 3 0 3D domain Glyco_hydro_65m PF03632.15 EGB09495.1 - 0.08 11.8 0.1 2.9 6.6 0.0 3.0 3 1 1 4 4 4 0 Glycosyl hydrolase family 65 central catalytic domain PPR_2 PF13041.6 EGB09495.1 - 0.1 12.8 0.1 6.1 7.1 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family DUF1670 PF07900.11 EGB09495.1 - 0.18 11.1 0.0 4.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1670) TPR_3 PF07720.12 EGB09495.1 - 0.27 11.3 4.8 0.72 9.9 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGB09495.1 - 1.7 8.7 9.7 9.9 6.3 0.3 4.4 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain DEAD PF00270.29 EGB09496.1 - 4.9e-48 163.2 0.1 1.8e-47 161.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB09496.1 - 1.3e-31 109.2 0.0 7.3e-31 106.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB09496.1 - 2.2e-05 24.5 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGB09496.1 - 0.0021 17.5 5.2 0.0063 15.9 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Sugar_tr PF00083.24 EGB09497.1 - 1.1e-20 74.0 6.3 1.2e-20 73.8 6.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB09497.1 - 7.8e-14 51.4 21.6 1e-13 51.0 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_Dp1 PF16938.5 EGB09497.1 - 0.31 11.3 3.5 0.55 10.5 1.0 2.4 2 0 0 2 2 2 0 Putative phage holin Dp-1 Sel1 PF08238.12 EGB09498.1 - 4.5e-62 205.1 32.6 2.8e-08 34.2 0.0 11.2 11 0 0 11 11 11 10 Sel1 repeat DUF1952 PF09189.10 EGB09498.1 - 3.8e-06 26.6 0.7 1.2 9.1 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF1952) DUF3416 PF11896.8 EGB09498.1 - 0.0011 19.4 6.3 3.5 7.9 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3416) TPR_6 PF13174.6 EGB09498.1 - 0.002 18.6 13.7 27 5.7 0.1 7.8 8 2 0 8 8 8 0 Tetratricopeptide repeat DIOX_N PF14226.6 EGB09498.1 - 0.0055 17.5 0.3 7.7 7.3 0.0 3.5 2 1 1 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal DGF-1_C PF11040.8 EGB09498.1 - 0.013 15.5 0.4 7.9 6.6 0.1 3.3 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF3710 PF12502.8 EGB09498.1 - 0.15 11.7 0.4 3.3 7.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3710) TPR_11 PF13414.6 EGB09498.1 - 0.74 9.6 7.0 1.2 8.8 0.7 3.8 3 2 0 3 3 3 0 TPR repeat AAA PF00004.29 EGB09499.1 - 6.5e-37 126.9 0.0 9.4e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB09499.1 - 1.9e-11 43.6 0.5 6.6e-11 41.8 0.5 2.1 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EGB09499.1 - 1.7e-07 31.1 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 EGB09499.1 - 7.4e-06 26.2 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGB09499.1 - 0.00055 20.2 0.2 0.11 12.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGB09499.1 - 0.0011 18.9 0.7 0.012 15.6 0.3 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGB09499.1 - 0.002 18.5 2.0 0.007 16.8 1.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGB09499.1 - 0.003 17.3 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EGB09499.1 - 0.0033 16.8 0.1 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGB09499.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 EGB09499.1 - 0.013 15.6 0.1 0.023 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGB09499.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGB09499.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EGB09499.1 - 0.043 13.4 5.0 0.6 9.6 0.5 3.1 1 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EGB09499.1 - 0.054 13.2 0.1 0.76 9.5 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGB09499.1 - 0.079 12.7 0.1 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EGB09499.1 - 0.093 12.2 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 EGB09499.1 - 0.15 12.6 0.1 0.3 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB09499.1 - 0.25 10.8 0.0 0.5 9.9 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NIF PF03031.18 EGB09500.1 - 1.9e-50 170.7 0.1 2.3e-50 170.4 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Frag1 PF10277.9 EGB09501.1 - 9.2e-05 22.1 9.1 0.00042 19.9 9.1 1.9 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family Ank_4 PF13637.6 EGB09502.1 - 4.5e-08 33.5 0.0 2.5e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Sulfotransfer_2 PF03567.14 EGB09502.1 - 0.00015 21.8 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 Sulfotransferase family Ank_2 PF12796.7 EGB09502.1 - 0.0002 21.9 0.0 0.00062 20.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) IQ PF00612.27 EGB09502.1 - 0.05 13.4 4.3 1.8 8.6 0.4 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif bZIP_2 PF07716.15 EGB09502.1 - 1.4 9.1 13.7 2.1 8.5 1.7 3.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF3018 PF11455.8 EGB09503.1 - 0.023 14.6 0.6 0.082 12.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Myb_DNA-binding PF00249.31 EGB09504.1 - 2.4e-38 130.0 14.5 1.4e-14 54.0 1.0 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB09504.1 - 4e-34 116.7 6.7 3.6e-14 52.8 0.1 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGB09504.1 - 0.00051 20.2 0.1 0.019 15.1 0.1 2.5 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EGB09504.1 - 0.00083 19.2 0.1 0.0098 15.8 0.0 2.4 2 0 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EGB09504.1 - 0.0049 17.1 5.9 3.9 7.9 0.2 3.2 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 EGB09504.1 - 0.0053 16.8 0.1 0.13 12.2 0.0 2.6 1 1 1 3 3 3 1 SLIDE HTH_AsnC-type PF13404.6 EGB09504.1 - 0.0085 15.9 0.1 0.05 13.4 0.0 2.3 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain Myb_DNA-bind_4 PF13837.6 EGB09504.1 - 0.014 15.8 13.3 0.099 13.0 1.5 3.9 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Death PF00531.22 EGB09504.1 - 0.054 13.7 0.4 7.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Death domain HTH_32 PF13565.6 EGB09504.1 - 0.079 13.6 0.3 0.2 12.3 0.3 1.7 1 0 0 1 1 1 0 Homeodomain-like domain adh_short PF00106.25 EGB09505.1 - 3.4e-24 85.4 0.0 5.8e-24 84.6 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB09505.1 - 7.8e-22 78.0 0.1 1.6e-21 77.0 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB09505.1 - 0.0029 17.6 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 KR domain MelC1 PF06236.11 EGB09507.1 - 0.038 14.1 0.6 0.43 10.7 0.1 2.2 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 Sulfotransfer_1 PF00685.27 EGB09508.1 - 2.1e-27 96.3 0.0 3.1e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain zf-MYND PF01753.18 EGB09508.1 - 2.4e-08 33.9 11.1 2.4e-08 33.9 11.1 2.3 2 0 0 2 2 2 1 MYND finger Sulfotransfer_3 PF13469.6 EGB09508.1 - 9.2e-06 26.2 0.0 9e-05 23.0 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase family TPR_11 PF13414.6 EGB09508.1 - 0.0026 17.4 2.4 0.8 9.4 0.0 3.3 3 0 0 3 3 3 2 TPR repeat Sel1 PF08238.12 EGB09508.1 - 0.006 17.2 6.3 0.17 12.6 2.6 3.4 2 0 0 2 2 2 1 Sel1 repeat TPR_16 PF13432.6 EGB09508.1 - 0.0098 16.5 7.6 0.0098 16.5 7.6 7.7 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09508.1 - 0.016 15.5 20.8 0.19 12.0 6.7 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09508.1 - 0.25 11.6 2.8 11 6.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09508.1 - 0.43 11.1 18.8 7.3 7.2 9.4 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 EGB09509.1 - 1.5e-46 158.4 0.0 2.2e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 EGB09509.1 - 2.2e-34 118.1 0.0 4.2e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGB09509.1 - 3.7e-05 23.8 0.0 6.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EGB09509.1 - 0.00086 19.4 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGB09509.1 - 0.039 14.3 0.0 0.095 13.1 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 TPT PF03151.16 EGB09510.1 - 2.8e-78 263.2 8.3 3.2e-78 263.0 8.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB09510.1 - 0.0018 18.4 27.1 0.0034 17.6 13.8 3.1 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGB09510.1 - 0.068 12.4 6.9 0.022 13.9 3.2 1.8 2 0 0 2 2 2 0 UAA transporter family Pkinase PF00069.25 EGB09511.1 - 2e-76 256.8 0.0 2.4e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09511.1 - 1.5e-34 119.5 0.0 2e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09511.1 - 5.6e-06 25.9 0.0 2.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGB09511.1 - 8.8e-05 22.0 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB09511.1 - 0.00068 19.6 0.0 0.63 9.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EGB09511.1 - 0.00089 18.9 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGB09511.1 - 0.012 14.5 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGB09511.1 - 0.076 12.6 0.2 0.29 10.7 0.0 1.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 EGB09512.1 - 4.9e-72 242.5 0.0 5.6e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09512.1 - 2.1e-42 145.2 0.0 2.5e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09512.1 - 4.1e-06 26.3 0.0 1.2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGB09512.1 - 0.016 14.8 0.1 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGB09512.1 - 0.07 12.6 0.1 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EGB09512.1 - 0.098 12.6 0.5 6.9 6.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGB09512.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cys_Met_Meta_PP PF01053.20 EGB09513.1 - 8.4e-121 403.1 0.0 9.2e-121 403.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGB09513.1 - 1.7e-07 30.8 0.0 4.8e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGB09513.1 - 0.00052 19.1 0.0 0.0009 18.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EGB09513.1 - 0.013 14.1 0.1 0.077 11.5 0.1 1.9 1 1 0 1 1 1 0 Methionine gamma-lyase VIT1 PF01988.19 EGB09514.1 - 2.1e-53 181.4 0.7 2.7e-53 181.0 0.7 1.1 1 0 0 1 1 1 1 VIT family UQ_con PF00179.26 EGB09515.1 - 6.9e-41 139.2 0.0 8.7e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGB09515.1 - 0.0095 15.8 0.1 0.018 14.9 0.1 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 EGB09515.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B ATP-grasp PF02222.22 EGB09516.1 - 3.3e-36 124.4 0.0 5.5e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EGB09516.1 - 2.2e-19 68.9 0.0 4.1e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EGB09516.1 - 0.001 18.6 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EGB09516.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain LAL_C2 PF18603.1 EGB09516.1 - 0.033 14.4 0.0 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Epimerase PF01370.21 EGB09516.1 - 0.043 13.3 0.1 0.092 12.2 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EGB09516.1 - 0.046 13.9 0.0 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EGB09516.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CLN3 PF02487.17 EGB09517.1 - 5.4e-90 302.3 1.4 2.1e-47 162.1 3.4 2.0 2 0 0 2 2 2 2 CLN3 protein TPR_2 PF07719.17 EGB09518.1 - 5.6e-16 57.3 16.8 3.2e-08 33.1 1.6 4.6 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09518.1 - 1.6e-14 52.8 4.6 9.9e-06 25.4 0.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09518.1 - 2.8e-14 52.2 9.7 9.6e-09 34.7 1.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGB09518.1 - 1.9e-13 49.7 6.6 0.00011 22.3 0.1 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09518.1 - 5.8e-13 49.3 11.2 3.1e-07 30.9 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09518.1 - 7.5e-10 39.2 9.3 0.00011 22.6 0.1 4.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09518.1 - 2.1e-07 31.1 5.0 0.0012 19.1 0.3 3.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB09518.1 - 2.5e-07 30.3 0.6 0.002 17.7 0.6 3.4 2 1 1 3 3 3 2 TPR repeat TPR_10 PF13374.6 EGB09518.1 - 5e-07 29.4 3.4 2.6e-05 23.9 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB09518.1 - 2.8e-05 24.6 10.6 0.051 14.4 0.2 4.4 4 1 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB09518.1 - 6.8e-05 23.0 8.5 0.0047 17.1 0.6 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGB09518.1 - 0.00011 22.0 3.7 0.034 14.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 EGB09518.1 - 0.013 15.5 0.1 0.091 12.9 0.1 2.1 1 1 1 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.6 EGB09518.1 - 0.028 15.1 9.7 0.064 13.9 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGB09518.1 - 0.035 13.5 0.0 0.085 12.2 0.0 1.5 1 1 1 2 2 2 0 Coatomer epsilon subunit Flavin_Reduct PF01613.18 EGB09518.1 - 0.071 13.2 0.1 0.27 11.3 0.0 1.8 1 1 1 2 2 2 0 Flavin reductase like domain TPR_4 PF07721.14 EGB09518.1 - 0.11 13.2 0.1 0.11 13.2 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4192 PF13830.6 EGB09518.1 - 0.4 10.7 10.8 3.2 7.7 9.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) GTP_EFTU PF00009.27 EGB09519.1 - 4.9e-58 195.9 0.1 7.2e-58 195.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGB09519.1 - 1.6e-37 128.0 0.1 2.8e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGB09519.1 - 3.8e-31 107.0 0.0 7.3e-31 106.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGB09519.1 - 2.8e-24 85.0 0.0 5.9e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGB09519.1 - 1.1e-13 51.3 0.0 3.2e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGB09519.1 - 6e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 EGB09519.1 - 0.0052 17.2 0.0 0.083 13.4 0.0 2.8 3 0 0 3 3 3 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 EGB09519.1 - 0.0073 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF442 PF04273.13 EGB09519.1 - 0.051 13.7 0.0 13 5.9 0.0 3.5 3 0 0 3 3 3 0 Putative phosphatase (DUF442) AIG1 PF04548.16 EGB09519.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Mito_carr PF00153.27 EGB09520.1 - 2.2e-48 162.1 1.2 9.2e-17 60.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 EGB09521.1 - 1.1e-33 116.6 0.0 1.1e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease SOUL PF04832.12 EGB09522.1 - 1.2e-36 126.5 0.0 1.6e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein Metal_resist PF13801.6 EGB09523.1 - 0.034 14.3 24.2 1.3 9.2 6.7 2.8 1 1 1 2 2 2 0 Heavy-metal resistance UBA PF00627.31 EGB09523.1 - 0.95 9.4 3.4 1.2 9.1 0.2 2.6 2 0 0 2 2 2 0 UBA/TS-N domain Ax_dynein_light PF10211.9 EGB09524.1 - 2.8e-78 262.1 2.1 3.2e-78 262.0 2.1 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain DivIC PF04977.15 EGB09524.1 - 0.0001 22.0 0.7 0.0001 22.0 0.7 2.7 3 0 0 3 3 3 1 Septum formation initiator Syntaxin-6_N PF09177.11 EGB09524.1 - 0.0018 18.8 1.0 0.0018 18.8 1.0 1.5 2 0 0 2 2 2 1 Syntaxin 6, N-terminal GrpE PF01025.19 EGB09524.1 - 0.0078 15.9 3.4 0.013 15.1 3.4 1.3 1 0 0 1 1 1 1 GrpE HOOK PF05622.12 EGB09524.1 - 0.008 14.4 5.7 0.0091 14.2 5.7 1.0 1 0 0 1 1 1 1 HOOK protein bZIP_1 PF00170.21 EGB09524.1 - 0.011 15.8 2.3 0.011 15.8 2.3 1.7 1 1 0 1 1 1 0 bZIP transcription factor TMCO5 PF14992.6 EGB09524.1 - 0.034 13.7 2.4 0.057 13.0 2.4 1.3 1 0 0 1 1 1 0 TMCO5 family YabA PF06156.13 EGB09524.1 - 0.039 14.6 1.6 0.078 13.6 1.6 1.5 1 0 0 1 1 1 0 Initiation control protein YabA FlaC_arch PF05377.11 EGB09524.1 - 0.12 12.8 1.5 0.3 11.5 1.5 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 EGB09524.1 - 0.2 12.1 6.1 0.42 11.1 6.1 1.6 1 1 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 EGB09524.1 - 0.35 11.4 7.4 0.4 11.2 6.4 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Ead_Ea22 PF13935.6 EGB09524.1 - 0.39 11.4 5.0 1.3 9.6 5.0 1.9 1 1 0 1 1 1 0 Ead/Ea22-like protein BCAS2 PF05700.11 EGB09524.1 - 0.53 10.0 5.6 4.7 6.9 1.7 2.4 2 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) ABC_tran_CTD PF16326.5 EGB09524.1 - 0.54 10.5 6.4 1.8 8.9 6.4 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 EGB09524.1 - 6 7.0 10.5 0.2 11.7 2.8 2.4 3 0 0 3 3 3 0 Basic region leucine zipper Glyco_hydro_47 PF01532.20 EGB09525.1 - 1.7e-146 488.8 0.0 2e-146 488.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MMR_HSR1 PF01926.23 EGB09525.1 - 2.2e-19 69.6 0.0 4.7e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Laminin_G_3 PF13385.6 EGB09525.1 - 2.1e-17 63.6 0.1 3.6e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily KH_2 PF07650.17 EGB09525.1 - 9.4e-14 51.0 0.0 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 EGB09525.1 - 1.8e-07 30.9 0.1 6.3e-07 29.0 0.0 1.9 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGB09525.1 - 9.7e-07 28.5 0.0 0.00089 18.8 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGB09525.1 - 0.00029 20.9 0.3 0.002 18.2 0.1 2.0 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 EGB09525.1 - 0.00044 19.6 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGB09525.1 - 0.0014 18.5 0.0 0.01 15.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGB09525.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 EGB09525.1 - 0.045 12.7 0.0 0.34 9.8 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EGB09525.1 - 0.21 11.8 0.0 1.2 9.4 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Amino_oxidase PF01593.24 EGB09526.1 - 6.6e-46 157.5 2.7 3.7e-33 115.5 0.1 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB09526.1 - 2.5e-09 37.2 0.7 2.5e-09 37.2 0.7 3.3 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGB09526.1 - 5.8e-06 25.8 1.2 9.4e-06 25.1 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 EGB09526.1 - 2.3e-05 23.7 2.7 2.3e-05 23.7 2.7 1.9 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 EGB09526.1 - 6.6e-05 22.7 1.8 6.6e-05 22.7 1.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGB09526.1 - 0.00017 21.1 5.3 0.00017 21.1 5.3 1.8 2 0 0 2 2 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGB09526.1 - 0.0003 20.1 0.2 0.00057 19.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGB09526.1 - 0.0015 17.8 1.4 0.0015 17.8 1.4 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB09526.1 - 0.0025 16.6 0.9 0.005 15.6 0.7 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EGB09526.1 - 0.0026 16.9 1.7 0.014 14.5 0.4 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 EGB09526.1 - 0.0084 16.7 1.0 0.022 15.3 1.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGB09526.1 - 0.053 12.8 0.5 0.087 12.1 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGB09526.1 - 0.086 11.9 1.4 0.13 11.3 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 EGB09526.1 - 0.12 12.6 0.1 0.87 9.9 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 EGB09526.1 - 0.28 10.4 0.2 0.44 9.7 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_2 PF13639.6 EGB09527.1 - 8.2e-10 38.9 6.4 8.2e-10 38.9 6.4 5.4 5 1 2 7 7 5 1 Ring finger domain zf-C2H2 PF00096.26 EGB09527.1 - 2e-09 37.4 19.7 0.24 11.9 0.0 8.2 8 0 0 8 8 7 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EGB09527.1 - 2.5e-08 34.0 2.5 0.0014 18.9 0.0 5.4 6 0 0 6 6 4 1 Zinc-finger double-stranded RNA-binding Cupin_8 PF13621.6 EGB09527.1 - 3e-08 33.7 0.1 0.0071 16.1 0.1 3.2 2 1 0 2 2 2 2 Cupin-like domain zf-rbx1 PF12678.7 EGB09527.1 - 1.1e-06 28.8 5.1 6.2e-06 26.4 5.1 2.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C2H2_4 PF13894.6 EGB09527.1 - 1.1e-05 25.8 41.0 0.3 12.0 0.0 9.6 11 0 0 11 11 8 3 C2H2-type zinc finger zf-met PF12874.7 EGB09527.1 - 1.5e-05 25.2 6.5 0.0022 18.3 0.0 5.7 7 0 0 7 7 5 1 Zinc-finger of C2H2 type zf-C3HC4_2 PF13923.6 EGB09527.1 - 3.7e-05 23.5 7.2 3.7e-05 23.5 7.2 3.7 6 0 0 6 6 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_2 PF12756.7 EGB09527.1 - 5.8e-05 23.4 4.3 1.6 9.2 0.0 5.5 4 2 2 6 6 6 1 C2H2 type zinc-finger (2 copies) zf-RING_11 PF17123.5 EGB09527.1 - 7.2e-05 22.4 4.1 7.2e-05 22.4 4.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger JmjC PF02373.22 EGB09527.1 - 0.00022 21.6 0.2 0.0034 17.8 0.0 2.2 1 1 1 2 2 2 1 JmjC domain, hydroxylase zf-C3HC4_3 PF13920.6 EGB09527.1 - 0.0005 19.9 4.4 0.0005 19.9 4.4 4.2 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB09527.1 - 0.00081 19.3 4.4 0.00081 19.3 4.4 4.1 3 2 0 3 3 3 1 zinc-RING finger domain zf-H2C2_2 PF13465.6 EGB09527.1 - 0.00095 19.5 8.4 5.9 7.5 0.0 5.4 5 0 0 5 5 5 1 Zinc-finger double domain zf-C3HC4 PF00097.25 EGB09527.1 - 0.0019 18.0 5.9 0.0019 18.0 5.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGB09527.1 - 0.0025 17.4 3.9 0.0025 17.4 3.9 3.1 4 0 0 4 4 2 1 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 EGB09527.1 - 0.0027 17.5 7.0 0.26 11.2 0.3 3.4 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 EGB09527.1 - 0.0086 16.1 1.3 0.042 13.9 1.3 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4187 PF13821.6 EGB09527.1 - 0.012 15.4 9.1 0.13 12.1 1.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) Ank_2 PF12796.7 EGB09527.1 - 0.021 15.4 0.0 0.058 14.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Cupin_4 PF08007.12 EGB09527.1 - 0.028 13.9 0.9 0.047 13.1 0.9 1.2 1 0 0 1 1 1 0 Cupin superfamily protein zf-C2H2_6 PF13912.6 EGB09527.1 - 0.056 13.5 18.6 0.13 12.3 0.0 6.1 7 0 0 7 7 5 0 C2H2-type zinc finger Ank_3 PF13606.6 EGB09527.1 - 0.064 13.8 0.1 0.39 11.4 0.1 2.4 1 0 0 1 1 1 0 Ankyrin repeat zf_C2H2_6 PF18450.1 EGB09527.1 - 0.079 12.7 0.9 0.44 10.3 0.9 2.4 1 0 0 1 1 1 0 Zinc Finger domain Cupin_2 PF07883.11 EGB09527.1 - 0.17 11.6 0.4 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Cupin domain TPR_2 PF07719.17 EGB09527.1 - 0.28 11.4 12.9 0.11 12.7 0.8 4.5 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09527.1 - 1.6 9.1 7.0 1.1 9.6 0.9 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat Prok-RING_1 PF14446.6 EGB09527.1 - 3 7.9 21.6 9.3 6.3 0.1 5.8 6 1 1 7 7 6 0 Prokaryotic RING finger family 1 zf-CHCC PF10276.9 EGB09527.1 - 4.8 7.3 8.4 1.7 8.8 0.5 3.7 3 0 0 3 3 3 0 Zinc-finger domain Ank_5 PF13857.6 EGB09527.1 - 9.2 6.7 6.6 1.5 9.2 0.2 2.9 3 1 0 3 3 2 0 Ankyrin repeats (many copies) UQ_con PF00179.26 EGB09528.1 - 1e-22 80.3 0.0 1.3e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGB09528.1 - 1.2e-05 25.2 0.0 3.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 UEV domain Lipoprotein_1 PF00820.19 EGB09528.1 - 0.0041 16.2 0.0 0.0049 16.0 0.0 1.1 1 0 0 1 1 1 1 Borrelia lipoprotein RWD PF05773.22 EGB09528.1 - 0.049 13.9 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain cNMP_binding PF00027.29 EGB09529.1 - 1.2e-06 28.5 0.0 3.2e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RGS PF00615.19 EGB09529.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 Regulator of G protein signaling domain Nucleotid_trans PF03407.16 EGB09530.1 - 0.00048 20.2 0.0 0.00076 19.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Laminin_G_3 PF13385.6 EGB09530.1 - 0.0072 16.5 0.2 0.2 11.8 0.2 2.8 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EGB09530.1 - 0.039 14.5 0.0 0.085 13.4 0.0 1.6 1 1 0 1 1 1 0 Laminin G domain Laminin_G_1 PF00054.23 EGB09530.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.6 1 1 0 1 1 1 0 Laminin G domain PAP_central PF04928.17 EGB09531.1 - 2.1e-64 216.9 0.0 2.7e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGB09531.1 - 5.2e-07 29.4 0.0 7.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGB09531.1 - 1.8e-06 28.1 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EGB09531.1 - 8.3e-05 22.4 0.0 0.00019 21.3 0.0 1.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain CarboxypepD_reg PF13620.6 EGB09532.1 - 0.46 10.8 5.6 19 5.6 0.4 4.3 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain Adaptin_binding PF10199.9 EGB09532.1 - 1.7 9.2 4.6 6.6 7.4 4.6 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Peptidase_C69 PF03577.15 EGB09535.1 - 1.5e-15 57.1 0.0 4.3e-13 48.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family C69 Cecropin PF00272.19 EGB09535.1 - 0.2 11.4 0.8 0.6 9.9 0.8 1.9 1 0 0 1 1 1 0 Cecropin family FeS_assembly_P PF01883.19 EGB09536.1 - 1.9e-09 37.5 0.3 3.2e-09 36.8 0.1 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein Sulfotransfer_3 PF13469.6 EGB09537.1 - 2.8e-07 31.2 1.5 2.8e-07 31.2 1.5 2.6 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB09537.1 - 8.5e-06 25.4 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain PKD_channel PF08016.12 EGB09538.1 - 4.6e-06 25.6 8.5 4.6e-06 25.6 8.5 1.8 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EGB09538.1 - 0.00031 20.1 10.9 0.00031 20.1 10.9 1.7 2 0 0 2 2 2 1 Ion transport protein Peptidase_M24 PF00557.24 EGB09539.1 - 3.5e-40 137.9 0.5 7.4e-40 136.9 0.1 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 RPN7 PF10602.9 EGB09539.1 - 1.9e-22 79.8 0.0 4.1e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGB09539.1 - 1.1e-10 41.9 0.0 2.9e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 PCI domain TFIIF_alpha PF05793.12 EGB09539.1 - 0.22 10.0 24.5 0.19 10.3 23.2 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rtf2 PF04641.12 EGB09539.1 - 0.34 10.2 14.3 0.65 9.3 14.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4604 PF15377.6 EGB09539.1 - 0.44 11.0 27.4 0.95 9.9 27.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CDC45 PF02724.14 EGB09539.1 - 2 6.6 12.2 3.8 5.7 12.2 1.4 1 0 0 1 1 1 0 CDC45-like protein U3_snoRNA_assoc PF08297.11 EGB09539.1 - 4.3 8.1 12.7 4.3 8.1 1.3 2.6 2 0 0 2 2 2 0 U3 snoRNA associated SRP-alpha_N PF04086.13 EGB09539.1 - 7.2 6.4 16.4 52 3.6 16.5 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SBF PF01758.16 EGB09540.1 - 2.7e-35 121.8 15.1 2.7e-35 121.8 15.1 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 EGB09540.1 - 5.8e-17 62.0 22.1 8.3e-17 61.5 22.1 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) EGF_2 PF07974.13 EGB09541.1 - 0.0013 19.0 8.7 0.0013 19.0 8.7 3.1 2 0 0 2 2 2 1 EGF-like domain zf-C3HC4_3 PF13920.6 EGB09542.1 - 8.6e-11 41.5 10.4 1.4e-10 40.8 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB09542.1 - 0.00029 20.6 11.1 0.0005 19.9 11.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TniQ PF06527.11 EGB09542.1 - 0.079 13.7 0.6 0.6 10.8 0.4 2.3 2 0 0 2 2 2 0 TniQ zf-RING_2 PF13639.6 EGB09542.1 - 0.088 13.2 11.7 0.16 12.4 11.7 1.4 1 0 0 1 1 1 0 Ring finger domain DUF3090 PF11290.8 EGB09542.1 - 4.1 7.2 5.9 0.72 9.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) ADH_N PF08240.12 EGB09543.1 - 1.1e-25 89.6 3.1 1.7e-25 89.0 3.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGB09543.1 - 7.1e-16 58.4 1.6 7.1e-16 58.4 1.6 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGB09543.1 - 3e-05 25.1 0.1 6.9e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGB09543.1 - 0.00087 18.7 0.1 0.0017 17.8 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGB09543.1 - 0.0012 19.0 0.2 0.0017 18.5 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGB09543.1 - 0.0041 16.8 0.2 0.006 16.2 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EGB09543.1 - 0.026 13.8 1.1 0.055 12.8 1.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 EGB09545.1 - 3.2e-115 384.9 0.3 3.6e-115 384.7 0.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EGB09545.1 - 4.7e-05 22.9 0.8 7.6e-05 22.3 0.8 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGB09545.1 - 7.7e-05 21.8 1.7 0.00073 18.6 0.8 2.7 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGB09545.1 - 0.00039 19.7 1.1 0.028 13.6 0.1 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase ThiG PF05690.14 EGB09545.1 - 0.00095 18.5 1.2 0.32 10.2 0.3 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 EGB09545.1 - 0.068 12.5 0.1 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase Cytochrom_C1 PF02167.15 EGB09546.1 - 1.4e-92 309.3 0.0 1.7e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EGB09546.1 - 0.00028 21.1 0.0 0.00061 20.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EGB09546.1 - 0.018 16.2 0.1 0.036 15.2 0.1 1.6 1 1 0 1 1 1 0 Cytochrome c Aldo_ket_red PF00248.21 EGB09547.1 - 2e-36 125.7 0.0 4.3e-35 121.3 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltransf_11 PF08241.12 EGB09548.1 - 1.6e-11 44.6 0.0 2.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB09548.1 - 7.9e-07 29.7 0.0 1.7e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB09548.1 - 2e-06 27.3 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGB09548.1 - 3.5e-05 23.6 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB09548.1 - 0.00065 20.4 0.0 0.0013 19.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09548.1 - 0.0062 16.4 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGB09548.1 - 0.0065 16.3 0.0 0.0072 16.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Abhydrolase_1 PF00561.20 EGB09549.1 - 8.4e-05 22.3 0.1 0.00017 21.4 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EGB09549.1 - 0.0039 17.1 0.1 0.0074 16.2 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.20 EGB09549.1 - 0.012 15.8 0.1 0.026 14.6 0.1 1.6 2 0 0 2 2 2 0 Thioesterase domain FKBP_C PF00254.28 EGB09550.1 - 8.5e-20 70.9 0.0 9.1e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase VIT_2 PF13757.6 EGB09550.1 - 0.097 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Cas_Csa4 PF09703.10 EGB09551.1 - 0.023 14.1 0.0 0.025 13.9 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) PDEase_I PF00233.19 EGB09552.1 - 5.2e-64 216.2 0.0 5.8e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase F5_F8_type_C PF00754.25 EGB09553.1 - 1.7e-12 47.6 0.1 3.7e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain Smr PF01713.21 EGB09553.1 - 8.2e-07 29.3 0.1 2.1e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 EGB09553.1 - 2e-05 24.9 24.0 0.12 12.9 1.3 6.4 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger Paramecium_SA PF01508.16 EGB09553.1 - 0.00015 22.1 12.3 0.00015 22.1 12.3 24.3 20 6 3 23 23 23 4 Paramecium surface antigen domain zf_CCCH_4 PF18345.1 EGB09553.1 - 0.26 11.4 10.2 0.14 12.2 3.2 4.9 2 0 0 2 2 2 0 Zinc finger domain DEAD PF00270.29 EGB09554.1 - 1.9e-17 63.6 0.0 2.9e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB09554.1 - 8.5e-14 51.9 0.0 2.9e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGB09554.1 - 1.8e-09 38.2 0.7 4.5e-09 36.9 0.7 1.7 1 0 0 1 1 1 1 RecQ zinc-binding EH_Signature PF15611.6 EGB09554.1 - 0.09 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 EH_Signature domain ResIII PF04851.15 EGB09554.1 - 0.23 11.5 0.0 1.3 9.0 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.25 EGB09555.1 - 5.7e-102 339.8 0.0 8.6e-102 339.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGB09555.1 - 9.3e-39 132.0 0.0 1.6e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGB09555.1 - 3.6e-14 53.0 1.2 1e-13 51.6 0.2 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Proteasome PF00227.26 EGB09556.1 - 1.4e-29 103.0 0.2 1.9e-29 102.5 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit P-mevalo_kinase PF04275.14 EGB09557.1 - 6.8e-40 135.6 0.0 8.4e-40 135.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomevalonate kinase COX15-CtaA PF02628.15 EGB09558.1 - 0.12 11.4 1.4 8.3 5.4 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein Adaptin_N PF01602.20 EGB09559.1 - 4.6e-97 325.8 0.0 6.4e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGB09559.1 - 9.9e-21 74.5 0.8 9.9e-21 74.5 0.8 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGB09559.1 - 1.7e-06 27.8 1.6 0.024 14.9 0.1 4.6 3 1 1 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EGB09559.1 - 0.00011 22.6 0.5 0.00011 22.6 0.5 5.2 3 2 3 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 EGB09559.1 - 0.00053 20.4 4.4 0.11 13.0 0.0 5.1 3 1 1 4 4 4 2 HEAT-like repeat Nop14 PF04147.12 EGB09559.1 - 0.0094 14.2 29.8 0.013 13.7 29.8 1.1 1 0 0 1 1 1 1 Nop14-like family NPR3 PF03666.13 EGB09559.1 - 5.1 5.8 7.4 7.5 5.2 7.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec6 PF06046.13 EGB09560.1 - 4.5e-21 74.9 0.0 1.4e-20 73.2 0.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec6 DNA_pol_B_thumb PF14791.6 EGB09562.1 - 0.029 14.5 0.0 0.092 12.9 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase beta thumb Xpo1 PF08389.12 EGB09563.1 - 2.3e-08 34.2 0.0 6.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Exportin 1-like protein CDC37_M PF08565.11 EGB09564.1 - 2.7e-16 59.6 0.4 7.2e-16 58.2 0.1 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 EGB09564.1 - 3.8e-15 56.9 3.0 3.8e-15 56.9 3.0 2.3 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 EGB09564.1 - 2.2e-12 47.0 0.1 2.2e-12 47.0 0.1 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain Glu_synthase PF01645.17 EGB09565.1 - 2.3e-133 444.9 1.6 3.3e-133 444.4 1.6 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.21 EGB09565.1 - 2e-124 415.6 0.0 3.4e-124 414.8 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 EGB09565.1 - 1.6e-89 300.1 0.0 1.7e-88 296.7 0.0 2.4 3 0 0 3 3 3 1 Glutamate synthase central domain GXGXG PF01493.19 EGB09565.1 - 4.1e-63 212.4 3.7 9.7e-63 211.2 3.6 1.7 2 0 0 2 2 2 1 GXGXG motif FMN_dh PF01070.18 EGB09565.1 - 1.3e-06 27.7 4.5 1.3e-06 27.7 4.5 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ETF_alpha PF00766.19 EGB09566.1 - 4e-36 122.9 4.1 1.2e-35 121.4 1.6 2.4 2 1 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 EGB09566.1 - 5.4e-20 72.0 10.3 1e-19 71.1 10.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain FA_desaturase PF00487.24 EGB09567.1 - 1.4e-20 74.2 27.1 2.9e-20 73.2 27.1 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DUF1534 PF07551.11 EGB09568.1 - 0.015 15.1 6.8 0.027 14.2 2.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1534) PH PF00169.29 EGB09569.1 - 0.00032 21.2 0.0 0.00069 20.1 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 EGB09569.1 - 0.00066 19.9 0.0 0.002 18.4 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain GYF_2 PF14237.6 EGB09569.1 - 0.042 13.6 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 GYF domain 2 PH_11 PF15413.6 EGB09569.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain His_Phos_1 PF00300.22 EGB09570.1 - 3e-31 108.6 2.5 3.3e-31 108.5 2.5 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EF_TS PF00889.19 EGB09571.1 - 2.2e-30 105.9 8.7 1.8e-29 102.9 8.6 3.1 1 1 0 1 1 1 1 Elongation factor TS UBA PF00627.31 EGB09571.1 - 0.0066 16.3 0.1 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain NRIP1_repr_3 PF15689.5 EGB09571.1 - 0.17 12.2 0.0 0.48 10.7 0.0 1.7 1 1 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 3 UNC-93 PF05978.16 EGB09572.1 - 2.4e-22 79.3 11.4 2.4e-22 79.3 11.4 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGB09572.1 - 4.6e-14 52.1 41.9 1.7e-07 30.5 17.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Usp PF00582.26 EGB09572.1 - 1.9e-05 25.2 1.3 0.015 15.8 0.0 3.6 2 1 0 2 2 2 1 Universal stress protein family Pox_A_type_inc PF04508.12 EGB09573.1 - 3.2 7.8 11.4 47 4.1 0.1 5.8 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat XhlA PF10779.9 EGB09573.1 - 3.9 7.7 8.9 37 4.6 0.0 5.1 3 2 1 4 4 4 0 Haemolysin XhlA MAP65_ASE1 PF03999.12 EGB09574.1 - 4.6e-33 114.8 8.7 7.2e-33 114.2 8.7 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) SAD_SRA PF02182.17 EGB09574.1 - 1.4e-13 50.9 0.2 5e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 SAD/SRA domain 2OG-FeII_Oxy_2 PF13532.6 EGB09574.1 - 1.2e-09 38.6 0.0 3.2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-HC5HC2H PF13771.6 EGB09574.1 - 3e-06 27.4 6.3 3e-06 27.4 6.3 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGB09574.1 - 0.00057 20.0 3.9 0.00057 20.0 3.9 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 EGB09574.1 - 0.055 13.4 14.1 0.099 12.5 3.2 2.9 2 0 0 2 2 2 0 PHD-finger AMP-binding PF00501.28 EGB09575.1 - 1.2e-71 241.6 0.0 2.2e-71 240.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGB09575.1 - 4.1e-54 183.4 0.1 2.1e-53 181.1 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EGB09575.1 - 1.6e-48 164.8 2.6 1.6e-48 164.8 2.6 2.0 2 0 0 2 2 2 1 short chain dehydrogenase RRM_1 PF00076.22 EGB09575.1 - 3.9e-36 122.7 0.0 1e-10 41.2 0.0 4.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short_C2 PF13561.6 EGB09575.1 - 3.9e-34 118.2 4.8 7.5e-34 117.3 2.4 2.5 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGB09575.1 - 1.5e-21 77.0 0.1 2e-15 56.9 0.0 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family OST-HTH PF12872.7 EGB09575.1 - 4.9e-16 58.3 0.0 0.00074 19.3 0.0 5.4 5 0 0 5 5 5 3 OST-HTH/LOTUS domain PQ-loop PF04193.14 EGB09575.1 - 1.1e-15 57.2 1.4 2.1e-14 53.0 0.3 2.3 2 0 0 2 2 2 1 PQ loop repeat PP-binding PF00550.25 EGB09575.1 - 2.2e-15 56.8 0.0 5.6e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 EGB09575.1 - 1.7e-14 54.2 6.3 5.9e-12 45.9 2.8 2.7 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.19 EGB09575.1 - 8.2e-11 41.4 0.0 3.8e-09 36.0 0.0 2.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGB09575.1 - 1.5e-09 37.4 0.0 0.00042 19.5 0.0 2.6 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGB09575.1 - 6.3e-09 36.0 4.3 0.0044 16.9 0.5 4.0 2 1 0 2 2 2 2 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGB09575.1 - 1.4e-06 27.9 0.0 0.00087 18.8 0.0 2.7 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 EGB09575.1 - 7e-06 26.9 0.6 6.1e-05 23.9 0.6 2.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_7 PF16367.5 EGB09575.1 - 9e-05 22.5 0.0 0.24 11.6 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif ApbA PF02558.16 EGB09575.1 - 0.0085 15.7 0.2 0.019 14.6 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 EGB09575.1 - 0.023 14.3 1.3 6 6.3 0.5 2.5 2 0 0 2 2 2 0 NmrA-like family GST_C_2 PF13410.6 EGB09575.1 - 0.079 13.0 0.1 0.49 10.5 0.0 2.4 2 0 0 2 2 1 0 Glutathione S-transferase, C-terminal domain EF-hand_9 PF14658.6 EGB09575.1 - 0.11 12.9 0.0 4.5 7.7 0.0 3.3 4 0 0 4 4 2 0 EF-hand domain GST_N_3 PF13417.6 EGB09575.1 - 0.17 12.3 0.1 13 6.3 0.0 3.0 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain Ammonium_transp PF00909.21 EGB09576.1 - 2.2e-115 385.6 32.0 2.5e-115 385.4 32.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3188 PF11384.8 EGB09576.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Archease PF01951.16 EGB09577.1 - 6.4e-38 130.1 0.2 7.1e-38 130.0 0.2 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Ion_trans PF00520.31 EGB09578.1 - 1.8e-20 73.2 7.5 2.8e-20 72.6 7.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB09578.1 - 3.4e-11 43.0 4.0 3.4e-11 43.0 4.0 2.1 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 EGB09578.1 - 1.1e-08 35.1 0.0 5e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain IRK PF01007.20 EGB09578.1 - 0.038 13.8 2.0 0.12 12.2 1.9 1.7 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain MTHFR PF02219.17 EGB09578.1 - 0.085 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Ank_2 PF12796.7 EGB09579.1 - 0.029 14.9 0.0 0.048 14.3 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RCC1 PF00415.18 EGB09580.1 - 3.8e-35 120.3 6.9 9.6e-10 38.9 0.0 6.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB09580.1 - 6.2e-28 96.0 25.6 2.2e-07 30.5 0.3 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat 2OG-FeII_Oxy_2 PF13532.6 EGB09581.1 - 1.2e-07 32.1 0.0 1.4e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_5 PF13857.6 EGB09582.1 - 4.1e-13 49.3 3.1 8.3e-08 32.4 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB09582.1 - 4.8e-12 46.3 0.4 1.2e-07 32.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB09582.1 - 2.1e-08 34.6 0.1 0.00031 21.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB09582.1 - 1.1e-05 25.4 0.8 0.0045 17.4 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGB09582.1 - 0.00054 20.3 4.4 0.25 11.8 0.4 3.0 3 0 0 3 3 3 2 Ankyrin repeat WW PF00397.26 EGB09582.1 - 0.012 15.7 1.0 0.026 14.6 1.0 1.5 1 0 0 1 1 1 0 WW domain Mak10 PF04112.13 EGB09583.1 - 9.2e-16 57.8 0.0 4.6e-15 55.5 0.0 2.0 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Myosin_head PF00063.21 EGB09584.1 - 2.1e-177 591.4 0.0 6.8e-177 589.7 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) CCCAP PF15964.5 EGB09584.1 - 0.0051 15.2 1.8 0.0076 14.6 1.8 1.1 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family HXXSHH PF07586.11 EGB09584.1 - 0.013 15.1 2.0 0.031 13.9 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) AAA_22 PF13401.6 EGB09584.1 - 0.033 14.5 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB09584.1 - 0.04 14.3 3.3 0.045 14.1 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Anp1 PF03452.14 EGB09585.1 - 1.7e-31 109.6 0.0 2.7e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Anp1 DUF2285 PF10074.9 EGB09585.1 - 0.033 14.8 1.3 0.07 13.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) PH PF00169.29 EGB09586.1 - 1.5e-09 38.3 0.0 3.7e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 PH domain FKBP_C PF00254.28 EGB09588.1 - 1.7e-21 76.3 0.0 2.1e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribonuc_red_sm PF00268.21 EGB09589.1 - 4.1e-100 334.9 0.0 4.9e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Myb_DNA-binding PF00249.31 EGB09590.1 - 3.5e-16 59.1 0.1 3.9e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB09590.1 - 0.00011 22.3 0.1 0.00013 22.1 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB09590.1 - 0.00017 21.4 0.2 0.00019 21.3 0.2 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Tcp10_C PF07202.13 EGB09591.1 - 2.3e-33 115.6 0.5 2.6e-33 115.5 0.5 1.0 1 0 0 1 1 1 1 T-complex protein 10 C-terminus DUF2761 PF10959.8 EGB09591.1 - 0.048 13.7 0.0 0.29 11.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2761) Tyrosinase PF00264.20 EGB09592.1 - 2.2e-10 41.2 2.3 2.2e-10 41.2 2.3 2.7 2 1 0 2 2 2 1 Common central domain of tyrosinase Myb_DNA-binding PF00249.31 EGB09592.1 - 0.0013 18.9 0.6 0.0041 17.3 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB09592.1 - 0.01 16.1 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain D-ser_dehydrat PF14031.6 EGB09593.1 - 7.4e-16 58.6 0.1 7.1e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EGB09593.1 - 5.4e-11 42.6 0.1 7.7e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain fn3 PF00041.21 EGB09595.1 - 2.5e-07 31.0 0.1 5.7e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Cwf_Cwc_15 PF04889.12 EGB09595.1 - 4.6 6.9 26.3 1.3 8.7 4.0 4.1 4 0 0 4 4 4 0 Cwf15/Cwc15 cell cycle control protein Chlam_PMP PF02415.17 EGB09596.1 - 0.0034 17.8 3.2 3.1 8.5 0.1 5.0 5 1 0 5 5 5 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat HSP90 PF00183.18 EGB09597.1 - 6.9e-203 675.2 24.4 8.8e-203 674.9 24.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGB09597.1 - 3.1e-11 43.8 0.1 6.2e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGB09597.1 - 8e-08 32.2 0.2 2.8e-07 30.4 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.14 EGB09597.1 - 0.57 8.4 20.4 1.4 7.1 2.2 2.3 2 0 0 2 2 2 0 CDC45-like protein CobT PF06213.12 EGB09597.1 - 1.4 8.3 29.5 0.1 12.0 1.4 3.3 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 EGB09597.1 - 3.6 6.7 14.4 1.8 7.7 7.6 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Utp14 PF04615.13 EGB09597.1 - 6.1 5.3 23.2 0.026 13.1 3.5 2.4 2 0 0 2 2 2 0 Utp14 protein SDA1 PF05285.12 EGB09597.1 - 6.9 6.0 33.7 1.1 8.6 3.6 3.2 3 0 0 3 3 3 0 SDA1 Myosin_head PF00063.21 EGB09599.1 - 6.1e-62 209.8 0.0 6.8e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB09599.1 - 0.00091 19.6 0.2 0.0014 19.0 0.1 1.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB09599.1 - 0.019 15.2 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGB09599.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 EGB09599.1 - 0.059 13.1 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 EGB09599.1 - 0.082 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EGB09599.1 - 0.092 13.3 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Myosin_head PF00063.21 EGB09600.1 - 3.3e-49 167.7 0.0 9.8e-48 162.9 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) COG6 PF06419.11 EGB09601.1 - 3.9e-32 111.3 0.0 6.1e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Anoctamin PF04547.12 EGB09601.1 - 0.2 10.4 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel GATase_4 PF13230.6 EGB09602.1 - 1.2e-15 57.1 0.0 1.6e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EGB09602.1 - 9.8e-13 48.5 0.0 1.4e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GSHPx PF00255.19 EGB09603.1 - 1.1e-26 92.6 0.0 1.3e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase HSF_DNA-bind PF00447.17 EGB09604.1 - 5.3e-25 87.9 0.2 6.3e-25 87.6 0.2 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Phospholip_B PF04916.13 EGB09605.1 - 3.9e-118 395.3 0.0 5.2e-118 394.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase B DUF2786 PF10979.8 EGB09605.1 - 5.1 7.1 6.4 0.47 10.4 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) zf-RING_2 PF13639.6 EGB09606.1 - 4.9e-12 46.0 14.9 5.6e-12 45.8 14.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGB09606.1 - 1.4e-07 31.2 6.3 1.4e-07 31.2 6.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGB09606.1 - 7.1e-07 29.0 13.9 8.5e-07 28.7 13.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB09606.1 - 1.3e-06 28.6 12.4 1.6e-06 28.3 12.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGB09606.1 - 6.1e-06 26.2 7.7 6.1e-06 26.2 7.7 1.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGB09606.1 - 8.6e-06 25.5 12.5 1.1e-05 25.2 12.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB09606.1 - 2.3e-05 24.2 10.1 2.7e-05 23.9 10.1 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGB09606.1 - 3.6e-05 23.5 11.3 4.4e-05 23.3 11.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB09606.1 - 0.00035 20.5 12.1 0.00044 20.2 12.1 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGB09606.1 - 0.00051 20.0 6.5 0.00055 19.9 6.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 EGB09606.1 - 0.0066 16.7 3.8 0.0066 16.7 3.8 1.4 1 1 0 1 1 1 1 Zinc-ribbon like family zf-Nse PF11789.8 EGB09606.1 - 0.02 14.7 3.9 0.022 14.6 3.9 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tmpp129 PF10272.9 EGB09606.1 - 0.023 14.0 1.3 0.023 14.0 1.3 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor Zn_ribbon_17 PF17120.5 EGB09606.1 - 0.046 13.3 11.6 0.07 12.8 11.6 1.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGB09606.1 - 0.049 13.8 7.3 0.5 10.6 7.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EGB09606.1 - 2.5 8.3 11.7 6 7.1 11.7 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 EGB09606.1 - 9.5 6.5 13.2 50 4.2 13.2 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_17 PF13431.6 EGB09607.1 - 1.8e-14 53.0 14.0 0.14 12.6 0.1 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB09607.1 - 6.4e-11 42.1 119.3 0.0015 19.2 0.4 17.3 9 6 10 19 19 18 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGB09607.1 - 5.5e-10 38.6 42.1 0.014 15.5 0.0 12.0 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09607.1 - 5e-09 36.5 59.0 0.00012 22.6 0.4 10.5 9 3 2 11 11 10 5 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 EGB09607.1 - 0.00014 21.7 0.0 0.0041 17.0 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase TPR_8 PF13181.6 EGB09607.1 - 0.00028 20.8 7.3 24 5.5 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09607.1 - 0.0019 18.8 5.5 0.0019 18.8 5.5 14.0 12 3 2 14 14 12 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09607.1 - 0.0084 15.9 13.3 10 6.2 0.1 7.3 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09607.1 - 0.0099 16.1 61.3 0.27 11.5 0.7 10.4 10 2 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGB09607.1 - 0.02 14.6 13.9 0.39 10.5 0.1 5.5 6 0 0 6 6 6 0 TPR repeat NDK PF00334.19 EGB09607.1 - 0.026 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Nucleoside diphosphate kinase Peptidase_S9 PF00326.21 EGB09607.1 - 0.039 13.4 0.3 0.53 9.7 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family TPR_7 PF13176.6 EGB09607.1 - 0.24 11.5 21.7 12 6.2 0.2 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TRAPPC9-Trs120 PF08626.11 EGB09607.1 - 0.33 8.3 0.2 0.45 7.8 0.2 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit RRS1 PF04939.12 EGB09608.1 - 1.3e-36 125.9 0.2 1.6e-36 125.6 0.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Peptidase_C13 PF01650.18 EGB09609.1 - 2.9e-30 105.6 0.0 3.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Host_attach PF10116.9 EGB09609.1 - 0.00066 20.3 0.0 0.0018 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein required for attachment to host cells Peptidase_C14 PF00656.22 EGB09609.1 - 0.027 14.4 0.0 0.091 12.7 0.0 1.8 1 1 0 1 1 1 0 Caspase domain baeRF_family2 PF18844.1 EGB09609.1 - 0.068 13.2 0.6 0.82 9.7 0.2 2.1 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Acetyltransf_2 PF00797.17 EGB09610.1 - 3.9e-60 203.6 0.0 4.6e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase DUF3846 PF12957.7 EGB09610.1 - 0.034 14.5 0.0 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3846) Snf7 PF03357.21 EGB09611.1 - 1.7e-48 164.5 1.9 1.9e-48 164.3 1.9 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.20 EGB09611.1 - 0.0006 19.7 7.3 0.071 13.1 0.2 3.2 2 1 0 2 2 2 1 Prefoldin subunit WEMBL PF05701.11 EGB09611.1 - 0.0044 15.8 5.7 0.0054 15.5 5.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light AAA_13 PF13166.6 EGB09611.1 - 0.028 13.1 3.7 0.047 12.3 3.7 1.3 1 1 0 1 1 1 0 AAA domain SlyX PF04102.12 EGB09611.1 - 0.075 13.7 1.6 15 6.3 0.2 3.3 2 1 1 3 3 3 0 SlyX Atg14 PF10186.9 EGB09611.1 - 0.088 11.9 2.1 0.14 11.3 2.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med4 PF10018.9 EGB09611.1 - 0.11 12.2 3.1 0.14 11.8 0.5 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 OmpH PF03938.14 EGB09611.1 - 0.11 12.8 14.7 0.92 9.8 6.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SpoIISA_toxin PF14171.6 EGB09611.1 - 0.14 11.8 0.2 0.23 11.1 0.1 1.4 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Birna_VP2 PF01766.17 EGB09611.1 - 0.17 10.8 0.2 0.21 10.5 0.2 1.1 1 0 0 1 1 1 0 Birnavirus VP2 protein PGA_cap PF09587.10 EGB09611.1 - 0.18 11.2 0.8 0.23 10.9 0.8 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap MIS13 PF08202.11 EGB09611.1 - 0.22 10.8 4.1 0.31 10.3 4.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family YlqD PF11068.8 EGB09611.1 - 0.49 10.8 6.6 1.4 9.3 2.0 2.1 1 1 1 2 2 2 0 YlqD protein NPV_P10 PF05531.12 EGB09611.1 - 0.54 10.8 6.1 0.73 10.3 3.6 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 EGB09611.1 - 0.56 10.0 9.1 1.3 8.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EGB09611.1 - 0.78 9.8 7.0 3.1 7.9 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.6 EGB09611.1 - 1.3 9.0 5.6 0.86 9.6 1.2 2.1 1 1 0 2 2 2 0 FlxA-like protein Spc7 PF08317.11 EGB09611.1 - 1.5 7.6 7.7 4.7 6.0 7.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EGB09611.1 - 2.4 8.4 8.9 2.1 8.7 2.4 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain LPP PF04728.13 EGB09611.1 - 4.9 7.6 6.7 51 4.4 0.4 3.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper cNMP_binding PF00027.29 EGB09612.1 - 4.2e-34 116.5 0.2 2.8e-19 69.0 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGB09613.1 - 7.9e-27 94.3 0.0 8.9e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09613.1 - 3.7e-10 39.5 0.0 4.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09613.1 - 0.00078 18.9 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Asparaginase_2 PF01112.18 EGB09614.1 - 1.8e-97 326.0 9.4 2.2e-97 325.8 9.4 1.0 1 0 0 1 1 1 1 Asparaginase LRR_4 PF12799.7 EGB09615.1 - 1.2e-09 38.3 3.7 0.00084 19.7 0.1 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB09615.1 - 1.3e-09 37.7 0.5 0.0008 19.1 0.0 2.3 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EGB09615.1 - 2.6e-07 30.2 0.8 3 8.7 0.1 4.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 EGB09615.1 - 2.5e-05 23.9 0.9 0.95 9.7 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 EGB09615.1 - 0.0053 16.3 0.3 0.041 13.4 0.0 1.9 1 1 1 2 2 2 1 Leucine-rich repeat CUE PF02845.16 EGB09616.1 - 0.027 14.2 0.1 0.076 12.7 0.1 1.8 1 0 0 1 1 1 0 CUE domain UBA PF00627.31 EGB09616.1 - 0.042 13.8 0.0 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 UBA/TS-N domain Aa_trans PF01490.18 EGB09617.1 - 4.9e-31 107.8 9.7 6.4e-31 107.5 9.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-MYND PF01753.18 EGB09618.1 - 4.7e-06 26.6 16.0 4.7e-06 26.6 16.0 3.9 4 0 0 4 4 4 1 MYND finger Sad1_UNC PF07738.13 EGB09619.1 - 1.2e-26 93.3 0.0 1.3e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ARPC4 PF05856.12 EGB09620.1 - 3.3e-80 267.6 2.4 3.7e-80 267.4 2.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) P34-Arc PF04045.14 EGB09620.1 - 0.014 15.1 0.4 3.2 7.4 0.1 2.1 1 1 1 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc BPL_LplA_LipB PF03099.19 EGB09621.1 - 1.7e-09 37.7 0.0 2.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Beta_helix PF13229.6 EGB09622.1 - 2.7e-16 59.8 16.9 4.1e-09 36.5 0.9 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EGB09622.1 - 5.5e-10 38.9 10.1 1.1e-05 24.9 5.5 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Amino_oxidase PF01593.24 EGB09622.1 - 2.4e-06 27.1 0.1 0.033 13.5 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DUF5123 PF17161.4 EGB09622.1 - 0.0021 19.1 0.4 0.47 11.5 0.1 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF5123) UNC-93 PF05978.16 EGB09623.1 - 4.3e-13 49.3 5.6 9.2e-13 48.2 5.6 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 ABC_membrane PF00664.23 EGB09624.1 - 7.6e-48 163.5 2.4 1e-47 163.1 2.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB09624.1 - 2.3e-30 105.9 0.0 6.9e-30 104.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane_2 PF06472.15 EGB09624.1 - 2.7e-06 27.0 1.6 4.5e-06 26.3 1.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SMC_N PF02463.19 EGB09624.1 - 0.00021 20.8 0.0 0.0017 17.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGB09624.1 - 0.00095 19.5 0.3 0.014 15.7 0.1 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB09624.1 - 0.031 14.2 0.4 0.95 9.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 EGB09624.1 - 0.032 13.8 0.2 0.67 9.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EGB09624.1 - 0.035 14.5 5.1 0.034 14.5 1.2 3.0 2 2 1 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 EGB09624.1 - 0.054 13.2 0.2 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 EGB09624.1 - 0.078 12.4 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA PF00004.29 EGB09624.1 - 0.11 12.9 0.1 1.3 9.5 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EGB09624.1 - 0.12 12.5 0.4 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain Htr2 PF17909.1 EGB09624.1 - 0.13 12.6 3.5 0.63 10.3 3.5 2.2 1 0 0 1 1 1 0 Htr2 transmembrane domain Iron_permease PF04120.12 EGB09624.1 - 0.19 11.5 2.2 5.3 6.8 0.4 2.6 2 0 0 2 2 2 0 Low affinity iron permease AAA_15 PF13175.6 EGB09624.1 - 0.29 10.8 0.0 0.44 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EGB09624.1 - 0.94 9.2 10.7 0.22 11.2 0.6 3.8 2 1 1 3 3 3 0 AAA domain Glyco_hydro_20 PF00728.22 EGB09625.1 - 5.3e-70 236.6 0.0 7.5e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGB09625.1 - 8.7e-13 49.1 0.0 2.9e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGB09625.1 - 0.077 13.8 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 DUF108 PF01958.18 EGB09627.1 - 1e-28 99.5 0.1 1.8e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 EGB09627.1 - 6.7e-06 26.7 0.1 1.1e-05 26.0 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EGB09627.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GLTP PF08718.11 EGB09628.1 - 4.2e-17 62.8 0.0 7.7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PX PF00787.24 EGB09628.1 - 0.003 17.5 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 PX domain SET PF00856.28 EGB09628.1 - 0.023 15.1 0.0 0.16 12.3 0.0 2.3 2 1 0 2 2 2 0 SET domain Lipase_3 PF01764.25 EGB09628.1 - 0.089 12.7 0.4 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S46 PF10459.9 EGB09629.1 - 0.2 10.3 3.3 0.33 9.5 3.3 1.3 1 0 0 1 1 1 0 Peptidase S46 Amino_oxidase PF01593.24 EGB09630.1 - 1.9e-33 116.5 2.0 2.3e-33 116.2 2.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB09630.1 - 1.5e-09 37.9 1.0 3.7e-09 36.7 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGB09630.1 - 4.7e-07 29.4 1.6 4.7e-07 29.4 1.6 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGB09630.1 - 3.6e-05 23.1 0.2 6.3e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGB09630.1 - 7.4e-05 22.1 0.9 0.00012 21.4 0.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB09630.1 - 0.00067 20.2 1.0 0.0013 19.2 1.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB09630.1 - 0.0022 17.6 3.0 0.0022 17.6 3.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EGB09630.1 - 0.0025 17.1 0.8 0.0041 16.4 0.8 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EGB09630.1 - 0.0038 16.4 3.8 0.0038 16.4 3.8 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGB09630.1 - 0.015 14.7 3.9 0.022 14.1 3.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGB09630.1 - 0.046 12.4 1.0 0.067 11.9 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EGB09630.1 - 0.056 12.7 0.8 0.091 12.0 0.8 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB09630.1 - 0.1 11.7 1.3 0.14 11.2 1.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 EGB09630.1 - 0.17 11.5 0.2 0.27 10.8 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ion_trans PF00520.31 EGB09631.1 - 1.3e-12 47.5 8.9 2e-12 46.9 8.9 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB09631.1 - 9.1e-12 44.8 5.0 2.1e-11 43.6 5.0 1.6 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 EGB09631.1 - 8.2e-05 22.7 0.0 0.00025 21.2 0.0 1.8 1 1 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Big_9 PF17963.1 EGB09631.1 - 0.00023 21.8 1.4 0.00023 21.8 1.4 18.2 17 2 0 18 18 18 3 Bacterial Ig domain Cadherin_4 PF17803.1 EGB09631.1 - 0.0015 19.1 1.1 0.0015 19.1 1.1 16.0 16 1 0 16 16 16 4 Bacterial cadherin-like domain MFS_1 PF07690.16 EGB09632.1 - 3.9e-12 45.8 22.9 6.9e-12 45.0 22.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EGB09632.1 - 0.0018 17.2 4.0 0.0035 16.2 4.0 1.4 1 0 0 1 1 1 1 MFS_1 like family Mito_carr PF00153.27 EGB09633.1 - 3e-38 129.6 0.0 6.7e-14 51.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FAP206 PF12018.8 EGB09634.1 - 4.3e-79 265.9 0.0 1.2e-78 264.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function Zip PF02535.22 EGB09634.1 - 1.2e-33 116.7 0.4 2e-33 116.0 0.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter NAD_binding_9 PF13454.6 EGB09634.1 - 0.12 12.4 0.2 0.41 10.6 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sel1 PF08238.12 EGB09636.1 - 1.3e-19 70.2 13.1 2.8e-07 31.0 0.0 4.7 4 1 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB09636.1 - 0.00023 21.7 9.6 0.029 15.0 1.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB09636.1 - 0.00035 21.0 7.0 2.7 8.8 0.4 5.0 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB09636.1 - 0.00095 19.8 1.0 11 7.1 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09636.1 - 0.0029 17.9 3.6 0.027 14.7 0.2 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 EGB09636.1 - 0.0076 16.4 0.3 17 5.9 0.0 3.6 4 0 0 4 4 4 0 PPR repeat TPR_2 PF07719.17 EGB09636.1 - 0.047 13.8 0.2 0.047 13.8 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_lid_10 PF17872.1 EGB09636.1 - 0.057 13.5 0.1 0.5 10.5 0.1 2.1 1 1 1 2 2 2 0 AAA lid domain Flu_M1_C PF08289.11 EGB09636.1 - 0.093 13.0 0.0 1.4 9.2 0.1 2.0 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain TPR_8 PF13181.6 EGB09636.1 - 0.15 12.3 7.6 1.8 9.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09636.1 - 0.38 10.7 0.3 0.38 10.7 0.3 4.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB09636.1 - 0.55 10.7 4.3 12 6.5 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB09636.1 - 3.8 7.5 11.0 0.91 9.5 0.4 4.0 3 2 2 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGB09637.1 - 3.6e-22 78.7 0.1 6.5e-15 55.5 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB09637.1 - 2.2e-18 66.1 0.0 1.7e-09 37.7 0.0 3.2 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB09637.1 - 9.6e-18 62.5 0.0 0.0002 21.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGB09637.1 - 1.7e-17 62.9 0.1 0.00044 20.6 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGB09637.1 - 3.2e-17 62.6 0.1 1.3e-09 38.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EGB09638.1 - 5e-20 69.5 4.3 1.4e-06 27.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB09638.1 - 5.8e-18 65.1 6.2 1.3e-09 38.4 1.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB09638.1 - 4.2e-16 57.4 4.7 1.3e-05 24.7 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB09638.1 - 9.7e-12 43.8 0.8 0.014 14.8 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGB09638.1 - 7.2e-11 41.8 7.8 0.0031 17.3 0.0 3.4 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.6 EGB09638.1 - 1.2e-06 28.3 4.1 0.08 12.8 0.0 3.9 2 2 2 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 EGB09638.1 - 4.4e-05 23.8 0.2 0.0067 16.7 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGB09638.1 - 0.00043 21.1 0.4 0.23 12.3 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain DUF1980 PF09323.10 EGB09638.1 - 0.00068 19.6 0.2 0.14 12.0 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1980) EF-hand_14 PF17959.1 EGB09638.1 - 0.004 17.5 0.1 0.26 11.7 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain Styelin PF17562.2 EGB09638.1 - 0.027 14.8 4.1 1.1 9.6 0.5 3.1 2 1 1 3 3 3 0 Styelin WD40 PF00400.32 EGB09641.1 - 3.2e-50 167.0 10.2 2e-08 34.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09641.1 - 1.5e-11 44.4 0.1 0.21 11.9 0.0 5.7 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB09641.1 - 1.3e-08 34.2 1.4 0.5 9.3 0.1 5.2 1 1 5 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC_tran PF00005.27 EGB09642.1 - 1.3e-28 100.2 0.0 6.5e-28 98.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EGB09642.1 - 1e-05 25.8 0.1 2.5e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGB09642.1 - 1.8e-05 24.3 0.3 0.023 14.1 0.1 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB09642.1 - 6.9e-05 23.3 5.4 8.8e-05 23.0 3.8 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGB09642.1 - 0.0024 17.6 0.1 0.006 16.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGB09642.1 - 0.0027 17.6 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGB09642.1 - 0.0089 15.6 0.3 0.26 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGB09642.1 - 0.01 16.1 3.5 0.15 12.3 3.4 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EGB09642.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 EGB09642.1 - 0.022 14.9 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain KdpD PF02702.17 EGB09642.1 - 0.036 13.5 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Zeta_toxin PF06414.12 EGB09642.1 - 0.043 13.1 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 EGB09642.1 - 0.048 13.8 0.9 0.12 12.5 0.4 2.1 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EGB09642.1 - 0.081 12.9 0.2 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGB09642.1 - 0.11 13.0 0.0 0.34 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB09642.1 - 0.2 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Asp_Arg_Hydrox PF05118.15 EGB09643.1 - 4.3e-25 88.4 0.0 7.1e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cellulase PF00150.18 EGB09645.1 - 4.5e-48 164.1 1.8 2.1e-47 161.9 1.8 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.25 EGB09646.1 - 1.6e-34 119.1 0.0 2.1e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB09646.1 - 4.3e-30 105.0 0.0 5.3e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB09646.1 - 4.6e-08 33.2 0.0 7.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGB09646.1 - 7.2e-05 22.8 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 EGB09646.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pribosyltran PF00156.27 EGB09647.1 - 1.9e-10 40.5 0.0 4.9e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EGB09647.1 - 7.6e-07 29.3 0.0 3.3e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EGB09647.1 - 0.00093 19.1 0.0 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase UPRTase PF14681.6 EGB09647.1 - 0.017 14.6 0.0 0.053 13.0 0.0 1.7 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase PP2C PF00481.21 EGB09648.1 - 5.5e-57 193.3 0.0 6.2e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB09648.1 - 8.1e-11 42.0 3.7 1.5e-10 41.1 3.7 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C RexB PF15968.5 EGB09648.1 - 0.14 12.6 0.2 4.6 7.7 0.1 2.1 1 1 1 2 2 2 0 Membrane-anchored ion channel, Abi component Pyrid_oxidase_2 PF13883.6 EGB09649.1 - 4.1e-40 137.5 0.0 4.9e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EGB09649.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Snf7 PF03357.21 EGB09650.1 - 9.3e-30 103.5 18.9 1.1e-29 103.3 18.9 1.0 1 0 0 1 1 1 1 Snf7 OmpH PF03938.14 EGB09650.1 - 2.9 8.2 12.3 35 4.7 12.3 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 EGB09650.1 - 4.2 7.7 10.4 35 4.7 10.4 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Fzo_mitofusin PF04799.13 EGB09650.1 - 4.8 6.7 8.8 0.36 10.4 0.8 2.2 2 1 0 2 2 2 0 fzo-like conserved region Hydrolase PF00702.26 EGB09651.1 - 5.7e-19 69.2 0.0 6.9e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGB09651.1 - 1.7e-17 64.1 0.0 8.4e-17 61.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB09651.1 - 1.4e-05 25.0 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EGB09651.1 - 0.018 15.1 0.0 0.077 13.1 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DnaJ PF00226.31 EGB09652.1 - 5.6e-20 71.2 1.5 2.4e-19 69.2 1.5 1.8 1 1 0 1 1 1 1 DnaJ domain DUF1490 PF07371.12 EGB09652.1 - 0.058 13.5 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) MFS_1 PF07690.16 EGB09653.1 - 2.6e-20 72.7 40.3 2.6e-20 72.7 40.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S8 PF00082.22 EGB09654.1 - 5.4e-06 25.9 1.1 1.9e-05 24.1 0.6 1.9 1 1 1 2 2 2 1 Subtilase family Pkinase PF00069.25 EGB09655.1 - 1.2e-30 106.8 0.0 1.3e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09655.1 - 4.4e-19 68.8 0.0 4.7e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB09655.1 - 4.1e-07 29.1 0.0 5.2e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB09655.1 - 0.023 14.1 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB09655.1 - 0.025 14.5 0.2 0.031 14.2 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran PF00005.27 EGB09656.1 - 7.9e-43 146.3 0.0 2.8e-29 102.4 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGB09656.1 - 1.8e-35 122.9 1.3 4.2e-19 69.2 0.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region Beta_helix PF13229.6 EGB09656.1 - 6.5e-12 45.6 11.8 1.1e-09 38.4 0.3 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EGB09656.1 - 9.7e-09 34.8 0.5 0.00024 20.5 0.0 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) SMC_N PF02463.19 EGB09656.1 - 6e-08 32.4 0.8 0.098 12.1 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB09656.1 - 1.7e-07 31.8 13.0 0.00056 20.3 2.9 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 EGB09656.1 - 1.1e-06 28.7 0.6 0.19 11.5 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB09656.1 - 0.00021 21.0 0.0 0.63 9.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB09656.1 - 0.00087 19.8 0.0 0.56 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGB09656.1 - 0.0018 18.4 0.0 0.95 9.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGB09656.1 - 0.0051 17.1 0.3 6.4 7.1 0.2 3.0 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGB09656.1 - 0.0062 16.5 0.0 4 7.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase DUF1565 PF07602.11 EGB09656.1 - 0.028 13.7 3.2 3.5 6.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1565) MeaB PF03308.16 EGB09656.1 - 0.042 12.8 0.2 0.083 11.9 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGB09656.1 - 0.042 13.9 0.0 9.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EGB09656.1 - 0.045 13.8 0.2 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain CbiA PF01656.23 EGB09656.1 - 0.083 12.9 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 EGB09656.1 - 0.14 11.1 0.0 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 EGB09656.1 - 0.56 9.7 6.5 1.3 8.6 3.3 3.1 2 1 0 2 2 2 0 AAA domain JAB PF01398.21 EGB09657.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.8 1 1 1 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SinI PF08671.10 EGB09657.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Anti-repressor SinI DAGK_cat PF00781.24 EGB09658.1 - 2.7e-20 72.3 1.2 4.2e-20 71.6 1.2 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EGB09658.1 - 0.032 13.4 0.3 0.053 12.7 0.3 1.4 1 0 0 1 1 1 0 ATP-NAD kinase Tim54 PF11711.8 EGB09658.1 - 0.078 11.8 0.2 4.7 5.9 0.0 2.1 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 BTB PF00651.31 EGB09659.1 - 0.0014 18.8 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3782 PF12644.7 EGB09659.1 - 0.13 12.4 0.6 0.26 11.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Asp_Arg_Hydrox PF05118.15 EGB09660.1 - 5.6e-07 29.5 1.6 7.5e-07 29.1 0.3 1.8 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_3 PF13469.6 EGB09660.1 - 1e-06 29.3 0.9 3.8e-05 24.2 0.9 2.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB09660.1 - 0.00025 20.6 0.0 0.0015 18.1 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Glycos_transf_2 PF00535.26 EGB09661.1 - 4e-22 78.8 0.0 5.5e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB09661.1 - 7.7e-07 29.2 0.0 4.8e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 EGB09661.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase GlcNAc PF11397.8 EGB09661.1 - 0.004 16.6 0.0 0.042 13.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase (GlcNAc) Ricin_B_lectin PF00652.22 EGB09661.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain GCP_C_terminal PF04130.13 EGB09662.1 - 5.5e-15 55.6 0.0 1.3e-14 54.4 0.0 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGB09662.1 - 2.2e-08 34.1 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal EF-hand_1 PF00036.32 EGB09662.1 - 1e-06 27.8 0.0 0.035 13.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB09662.1 - 7.2e-05 22.4 0.0 0.017 15.0 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain Vps62 PF06101.11 EGB09662.1 - 0.00016 20.1 0.0 0.00025 19.5 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Na_trans_assoc PF06512.13 EGB09662.1 - 0.00022 21.6 0.8 0.00043 20.6 0.8 1.4 1 0 0 1 1 1 1 Sodium ion transport-associated EF-hand_7 PF13499.6 EGB09662.1 - 0.00045 20.6 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB09662.1 - 0.0045 16.4 0.1 0.089 12.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGB09662.1 - 0.16 11.8 0.0 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair CDC45 PF02724.14 EGB09662.1 - 0.31 9.3 3.3 0.51 8.6 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PAXIP1_C PF15364.6 EGB09662.1 - 0.62 10.4 7.7 1.4 9.2 7.7 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Spore_coat_CotO PF14153.6 EGB09662.1 - 1.4 8.9 8.1 2.4 8.0 8.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Roughex PF06020.11 EGB09662.1 - 1.4 8.0 8.6 2.7 7.0 8.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF4746 PF15928.5 EGB09662.1 - 3 7.2 9.0 5.3 6.4 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Usp PF00582.26 EGB09662.1 - 3.4 8.2 11.5 2 8.9 7.4 2.9 2 0 0 2 2 1 0 Universal stress protein family Cys_Met_Meta_PP PF01053.20 EGB09663.1 - 5.6e-121 403.7 0.0 6.7e-121 403.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CoA_binding_2 PF13380.6 EGB09663.1 - 3.3e-34 117.9 2.6 4.5e-34 117.4 0.3 2.4 3 1 0 3 3 3 1 CoA binding domain Aminotran_1_2 PF00155.21 EGB09663.1 - 0.007 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II NIPSNAP PF07978.13 EGB09663.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 NIPSNAP Beta_elim_lyase PF01212.21 EGB09663.1 - 0.018 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGB09663.1 - 0.028 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DDE_Tnp_4 PF13359.6 EGB09664.1 - 4.7e-13 49.1 0.0 5.6e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease REJ PF02010.15 EGB09665.1 - 8.4e-31 107.2 0.0 4.8e-30 104.8 0.0 1.9 1 1 0 1 1 1 1 REJ domain Laminin_G_3 PF13385.6 EGB09665.1 - 3.7e-12 46.7 3.1 1.2e-11 45.0 0.9 2.8 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 EGB09665.1 - 0.15 11.7 0.0 0.4 10.4 0.0 1.6 1 1 0 1 1 1 0 Pentaxin family Kinesin PF00225.23 EGB09666.1 - 5.6e-97 324.6 0.0 6.4e-97 324.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB09666.1 - 3.1e-22 79.1 0.0 4.7e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 EGB09666.1 - 0.08 13.3 1.9 0.13 12.6 1.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_C1 PF00112.23 EGB09667.1 - 2.1e-61 207.8 0.7 2.7e-61 207.4 0.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB09667.1 - 1e-11 45.1 0.0 1.6e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB09667.1 - 2.7e-06 26.5 0.7 0.00034 19.5 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Cpn10 PF00166.21 EGB09668.1 - 3e-31 107.3 0.0 6.4e-15 55.0 0.1 2.4 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit ADH_zinc_N PF00107.26 EGB09669.1 - 1.9e-22 79.6 0.1 3.8e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGB09669.1 - 1.8e-15 58.1 0.0 6.8e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB09669.1 - 2.8e-06 27.2 2.4 2.9e-06 27.1 0.1 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGB09669.1 - 0.00032 20.5 0.2 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ACP_syn_III_C PF08541.10 EGB09669.1 - 0.043 14.0 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PK PF00224.21 EGB09670.1 - 1.1e-96 323.8 0.0 1.5e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGB09670.1 - 1.9e-26 92.6 0.0 4.1e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DUF2859 PF11072.8 EGB09670.1 - 0.021 14.5 0.3 0.05 13.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) DUF4253 PF14062.6 EGB09670.1 - 0.093 12.9 0.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) TPR_14 PF13428.6 EGB09671.1 - 0.0011 19.5 37.1 0.15 13.0 0.5 7.1 2 2 5 7 7 7 6 Tetratricopeptide repeat Suf PF05843.14 EGB09671.1 - 0.0034 17.4 0.0 0.84 9.6 0.0 2.4 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EGB09671.1 - 0.0055 17.2 27.3 8 7.1 0.1 5.3 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09671.1 - 0.14 12.4 1.5 1 9.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 EGB09672.1 - 1.7e-17 62.9 0.0 1.8e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB09672.1 - 5.4e-08 32.6 0.0 5.7e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB09672.1 - 0.0006 20.2 0.0 0.0036 17.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB09672.1 - 0.016 15.3 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 EGB09672.1 - 0.1 13.1 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TPT PF03151.16 EGB09673.1 - 4.8e-30 104.9 0.8 5.3e-30 104.8 0.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB09673.1 - 8.6e-06 26.0 6.1 1e-05 25.8 6.1 1.1 1 0 0 1 1 1 1 EamA-like transporter family DZR PF12773.7 EGB09675.1 - 0.001 19.1 1.5 0.0036 17.3 1.5 2.0 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EGB09675.1 - 0.0099 15.6 2.8 0.95 9.3 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 EGB09675.1 - 0.44 10.2 7.1 2.3 7.9 7.1 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 EGB09675.1 - 0.86 9.1 8.6 3 7.4 0.6 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 EGB09675.1 - 1.1 9.1 3.9 2.9 7.7 3.9 1.8 1 0 0 1 1 1 0 Rubredoxin metal binding domain Clat_adaptor_s PF01217.20 EGB09676.1 - 1.2e-40 138.7 3.1 1.4e-40 138.5 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Phage_sheath_1C PF17482.2 EGB09676.1 - 0.08 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain Peptidase_C12 PF01088.21 EGB09677.1 - 6.3e-46 156.8 0.0 7.7e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyco_hydro_28 PF00295.17 EGB09678.1 - 1e-29 103.7 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EGB09678.1 - 1.7e-10 41.1 0.7 1.2e-08 35.1 0.7 2.3 1 1 0 1 1 1 1 Pectate lyase superfamily protein Tyrosinase PF00264.20 EGB09679.1 - 5.9e-05 23.5 0.1 0.00071 19.9 0.1 2.4 2 1 0 2 2 2 1 Common central domain of tyrosinase PGM_PMM_III PF02880.16 EGB09680.1 - 3.4e-26 91.7 0.0 7.1e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 EGB09680.1 - 4.2e-26 91.3 0.0 6.9e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EGB09680.1 - 2.4e-15 57.0 0.2 1.6e-14 54.4 0.1 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGB09680.1 - 0.00094 19.3 0.0 0.0033 17.6 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ubiquitin PF00240.23 EGB09681.1 - 1.5e-61 204.1 5.1 4.3e-31 106.5 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EGB09681.1 - 1.4e-28 98.6 5.1 5.6e-14 51.7 0.8 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB09681.1 - 9.3e-13 48.5 0.9 3.5e-05 24.2 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB09681.1 - 3.8e-09 36.3 0.3 0.003 17.4 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB09681.1 - 1.1e-07 31.9 0.2 0.019 15.1 0.0 2.9 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGB09681.1 - 3.1e-07 30.7 0.4 0.012 16.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 EGB09681.1 - 5.6e-07 30.1 0.0 0.042 14.4 0.0 2.1 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGB09681.1 - 0.0024 17.9 3.1 7.2 6.7 0.0 3.8 4 0 0 4 4 4 2 Ubiquitin-like domain TmoB PF06234.12 EGB09681.1 - 0.009 16.1 0.5 5.8 7.1 0.1 2.7 2 2 0 2 2 2 2 Toluene-4-monooxygenase system protein B (TmoB) DUF2870 PF11069.8 EGB09681.1 - 0.029 14.8 0.0 8.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF1940 PF09155.10 EGB09681.1 - 0.031 14.4 0.5 8 6.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) Raf1_HTH PF18579.1 EGB09681.1 - 0.038 13.7 0.1 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain FGE-sulfatase PF03781.16 EGB09682.1 - 4.5e-33 114.9 1.3 1.2e-32 113.6 1.3 1.7 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 PP2C PF00481.21 EGB09682.1 - 3.6e-22 79.2 0.0 6.5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C 2OG-FeII_Oxy_3 PF13640.6 EGB09682.1 - 3e-15 56.9 0.0 6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_25 PF13649.6 EGB09682.1 - 6.1e-14 52.5 0.0 2.2e-13 50.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09682.1 - 1.6e-13 51.1 0.0 4.2e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09682.1 - 4.5e-12 46.1 0.0 9.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB09682.1 - 3.6e-11 43.1 0.0 6.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Glyco_tranf_2_3 PF13641.6 EGB09682.1 - 1.5e-08 34.8 0.9 5.9e-08 32.9 0.9 2.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGB09682.1 - 8.4e-08 32.2 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Methyltransf_12 PF08242.12 EGB09682.1 - 4.2e-07 30.6 0.0 1.3e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain EF-hand_7 PF13499.6 EGB09682.1 - 9.1e-07 29.2 0.1 0.1 13.1 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGB09682.1 - 1.3e-05 24.7 0.1 0.15 12.1 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 EGB09682.1 - 2e-05 23.8 0.0 0.055 13.0 0.0 3.6 3 0 0 3 3 3 1 EF hand Ubie_methyltran PF01209.18 EGB09682.1 - 8.3e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 2OG-FeII_Oxy_4 PF13661.6 EGB09682.1 - 8.7e-05 23.1 0.0 0.00054 20.6 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EGB09682.1 - 0.0073 16.7 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase EF-hand_8 PF13833.6 EGB09682.1 - 0.008 16.0 0.4 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair MTS PF05175.14 EGB09682.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PhyH PF05721.13 EGB09682.1 - 0.038 14.3 0.1 0.088 13.0 0.1 1.7 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) PCMT PF01135.19 EGB09682.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DHQS PF01959.16 EGB09683.1 - 1.8e-62 211.3 0.1 3.9e-62 210.2 0.1 1.5 1 1 0 1 1 1 1 3-dehydroquinate synthase II Hint PF01079.20 EGB09683.1 - 0.01 15.3 0.1 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Hint module SH3_3 PF08239.11 EGB09684.1 - 0.0001 22.5 0.2 0.019 15.2 0.0 2.8 2 1 0 2 2 2 2 Bacterial SH3 domain DUF1876 PF08962.11 EGB09684.1 - 0.84 9.6 0.0 0.84 9.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) PP2C PF00481.21 EGB09685.1 - 2e-38 132.5 0.0 3.4e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Ank_4 PF13637.6 EGB09685.1 - 1.5e-06 28.6 0.2 0.0002 21.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB09685.1 - 0.006 16.9 0.1 0.019 15.3 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB09685.1 - 0.11 13.1 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) EGF_2 PF07974.13 EGB09686.1 - 2e-12 47.3 61.1 2.7e-05 24.4 8.6 5.8 5 1 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 EGB09686.1 - 0.0068 16.5 6.1 0.0068 16.5 6.1 4.7 4 1 0 4 4 4 2 Laminin EGF domain EGF PF00008.27 EGB09686.1 - 1.9 8.8 50.8 2.8 8.3 6.7 6.0 6 0 0 6 6 6 0 EGF-like domain Chloroa_b-bind PF00504.21 EGB09687.1 - 2.5e-27 96.4 0.0 3.4e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein AAA_16 PF13191.6 EGB09688.1 - 0.00015 22.2 0.4 0.00015 22.2 0.4 2.6 2 0 0 2 2 2 1 AAA ATPase domain CHAT PF12770.7 EGB09688.1 - 0.00031 20.3 0.0 0.00072 19.0 0.0 1.6 1 0 0 1 1 1 1 CHAT domain HMG-CoA_red PF00368.18 EGB09688.1 - 0.019 14.0 0.1 0.039 13.0 0.1 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase TIP49 PF06068.13 EGB09688.1 - 0.069 12.3 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain DUF374 PF04028.13 EGB09688.1 - 0.69 9.5 3.2 3.4 7.3 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Cyt-b5 PF00173.28 EGB09689.1 - 3e-10 40.1 0.1 3.9e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PEP_mutase PF13714.6 EGB09691.1 - 3.2e-45 154.5 5.2 3.6e-45 154.3 5.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGB09691.1 - 4.4e-10 38.7 0.4 5.7e-10 38.3 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF1192 PF06698.11 EGB09691.1 - 0.013 15.5 3.3 0.39 10.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) SH3_9 PF14604.6 EGB09692.1 - 9.4e-05 22.2 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB09692.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain IQ PF00612.27 EGB09692.1 - 3.6 7.6 4.1 39 4.4 1.1 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif ShK PF01549.24 EGB09693.1 - 0.23 12.0 3.9 0.7 10.5 3.9 1.9 1 0 0 1 1 1 0 ShK domain-like Brix PF04427.18 EGB09694.1 - 5.6e-28 98.4 0.0 7.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Acyl-CoA_dh_1 PF00441.24 EGB09695.1 - 1.3e-36 126.0 0.0 2.3e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGB09695.1 - 8.7e-34 116.6 0.0 1.9e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGB09695.1 - 2.1e-27 95.2 0.2 3.8e-27 94.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGB09695.1 - 0.00018 21.8 0.2 0.00036 20.8 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF349 PF03993.12 EGB09695.1 - 0.33 11.3 1.1 1.6 9.1 1.1 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF4079 PF13301.6 EGB09696.1 - 3.6e-21 75.8 10.3 4.6e-21 75.4 5.3 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4079) UPF0242 PF06785.11 EGB09697.1 - 0.17 12.0 1.7 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase PF00069.25 EGB09698.1 - 2.1e-62 210.9 0.0 2.8e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09698.1 - 1.3e-30 106.5 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB09698.1 - 2.4e-07 30.4 0.0 3.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB09698.1 - 9.3e-06 25.1 0.1 1.7e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB09698.1 - 7.2e-05 21.7 0.0 0.00014 20.8 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGB09698.1 - 0.00025 21.0 0.6 0.0021 18.0 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB09698.1 - 0.0028 17.3 0.1 0.0051 16.4 0.0 1.5 2 0 0 2 2 2 1 RIO1 family HEAT_2 PF13646.6 EGB09698.1 - 0.024 15.0 0.1 1.7 9.1 0.1 2.8 3 0 0 3 3 3 0 HEAT repeats YrbL-PhoP_reg PF10707.9 EGB09698.1 - 0.045 13.3 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF705 PF05152.12 EGB09698.1 - 0.21 11.0 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Pox_ser-thr_kin PF05445.11 EGB09698.1 - 0.22 10.5 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MAPEG PF01124.18 EGB09699.1 - 2.5e-10 40.3 3.3 3e-10 40.1 3.3 1.1 1 0 0 1 1 1 1 MAPEG family WD40 PF00400.32 EGB09700.1 - 3.2e-24 84.7 10.9 3.1e-06 27.8 0.0 7.2 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09700.1 - 2.1e-18 66.4 1.8 9.5e-07 29.0 0.0 5.3 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGB09700.1 - 3.2e-08 33.3 1.2 0.015 15.2 0.0 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGB09700.1 - 4.4e-08 33.2 0.1 0.00095 19.1 0.0 3.3 1 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGB09700.1 - 1.4e-05 24.3 0.1 0.19 10.7 0.0 3.0 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGB09700.1 - 0.002 17.5 0.4 0.049 12.9 0.0 2.8 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 EGB09700.1 - 0.0032 17.1 0.2 0.0058 16.2 0.2 1.5 1 1 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.14 EGB09700.1 - 0.015 14.3 0.1 1.7 7.6 0.1 3.0 3 1 0 3 3 3 0 Coatomer WD associated region Proteasome_A_N PF10584.9 EGB09700.1 - 0.075 12.7 1.1 16 5.3 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.7 EGB09700.1 - 0.085 12.8 0.7 10 6.0 0.1 3.1 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Glyoxal_oxid_N PF07250.11 EGB09700.1 - 0.18 10.9 0.7 2.3 7.4 0.0 2.8 1 1 3 4 4 4 0 Glyoxal oxidase N-terminus Frtz PF11768.8 EGB09700.1 - 0.19 10.0 0.0 1.1 7.5 0.0 2.1 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz CTP_transf_like PF01467.26 EGB09701.1 - 2.9e-17 63.2 0.0 5.2e-17 62.4 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EGB09701.1 - 0.00052 19.9 0.3 0.0023 17.8 0.2 1.9 1 1 1 2 2 2 1 FAD synthetase ADH_zinc_N PF00107.26 EGB09701.1 - 0.13 12.3 0.1 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AF2331-like PF14556.6 EGB09701.1 - 0.14 12.8 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 AF2331-like ABC1 PF03109.16 EGB09702.1 - 2e-23 82.8 0.0 4e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Ricin_B_lectin PF00652.22 EGB09702.1 - 7.9e-06 26.1 0.0 0.0037 17.5 0.0 2.3 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain APH PF01636.23 EGB09702.1 - 7.9e-05 22.7 0.0 7.9e-05 22.7 0.0 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB09702.1 - 0.00028 20.5 0.0 0.008 15.8 0.0 2.4 2 0 0 2 2 2 1 RIO1 family zf-MYND PF01753.18 EGB09702.1 - 0.00057 19.9 4.6 0.00057 19.9 4.6 2.4 2 0 0 2 2 2 1 MYND finger zf-RING_2 PF13639.6 EGB09702.1 - 0.004 17.5 14.5 0.004 17.5 14.5 3.0 3 0 0 3 3 3 1 Ring finger domain Sel1 PF08238.12 EGB09702.1 - 0.0084 16.8 0.0 0.028 15.1 0.0 2.0 1 0 0 1 1 1 1 Sel1 repeat RicinB_lectin_2 PF14200.6 EGB09702.1 - 0.073 13.8 0.0 16 6.3 0.0 2.6 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like zf-RING_4 PF14570.6 EGB09702.1 - 0.26 11.1 15.0 0.78 9.6 15.0 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ResIII PF04851.15 EGB09703.1 - 2.5e-19 69.9 0.0 3.5e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGB09703.1 - 1.6e-06 28.4 0.0 2.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB09703.1 - 0.00015 21.6 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Methyltransf_21 PF05050.12 EGB09704.1 - 2.7e-13 50.3 0.0 4.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain PseudoU_synth_1 PF01416.20 EGB09704.1 - 1.1e-05 25.8 0.0 2.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridine synthase zf-C2H2_4 PF13894.6 EGB09704.1 - 0.026 15.4 0.2 0.051 14.4 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger FtsJ PF01728.19 EGB09704.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase GTP_cyclohydroI PF01227.22 EGB09705.1 - 1.5e-72 242.8 0.0 1.8e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGB09705.1 - 0.00064 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 QueF-like protein Ank_2 PF12796.7 EGB09706.1 - 5.6e-13 49.3 0.1 7.7e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09706.1 - 4.5e-12 45.0 1.2 7.9e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGB09706.1 - 1.7e-10 41.2 0.2 9.4e-08 32.5 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB09706.1 - 1.7e-06 28.2 1.6 0.0024 18.2 0.2 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB09706.1 - 1.3e-05 25.4 2.0 0.00045 20.4 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Hist_deacetyl PF00850.19 EGB09707.1 - 2.5e-57 194.7 0.3 3.9e-57 194.1 0.3 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PAH PF02671.21 EGB09707.1 - 0.0003 20.9 0.1 0.00055 20.0 0.1 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat eIF3g PF12353.8 EGB09707.1 - 0.13 12.7 0.2 0.26 11.7 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G 2OG-FeII_Oxy_4 PF13661.6 EGB09708.1 - 3.3e-13 50.1 0.0 5.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGB09708.1 - 2.7e-09 37.8 0.1 5.5e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 EGB09708.1 - 8.5e-06 25.5 0.1 0.00012 21.9 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09708.1 - 6e-05 23.5 0.3 0.00023 21.6 0.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Ofd1_CTDD PF10637.9 EGB09708.1 - 0.00021 20.7 0.0 0.0038 16.6 0.0 2.1 1 1 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term TPR_9 PF13371.6 EGB09708.1 - 0.0003 20.9 0.9 0.0017 18.4 0.8 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09708.1 - 0.00074 19.5 0.0 0.0021 18.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09708.1 - 0.0034 17.2 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EGB09708.1 - 0.031 14.3 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 EGB09708.1 - 0.046 14.6 0.2 0.046 14.6 0.2 4.7 3 2 1 4 4 3 0 Tetratricopeptide repeat Caskin-Pro-rich PF16907.5 EGB09708.1 - 0.06 13.9 0.8 0.16 12.5 0.8 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Pkinase PF00069.25 EGB09709.1 - 1.6e-51 175.3 0.0 2.1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09709.1 - 2.2e-23 82.9 0.0 7.5e-23 81.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB09709.1 - 0.0097 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Castor_Poll_mid PF06241.12 EGB09711.1 - 1.7e-33 114.7 0.0 2.2e-31 107.9 0.0 2.5 2 0 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 EGB09711.1 - 0.0061 16.4 0.0 0.021 14.6 0.0 2.0 1 0 0 1 1 1 1 TrkA-C domain RSN1_7TM PF02714.15 EGB09712.1 - 6.9e-60 202.7 10.8 1e-59 202.1 10.8 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGB09712.1 - 1.9e-28 99.2 0.1 1.9e-28 99.2 0.1 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGB09712.1 - 4.9e-19 69.2 0.0 7.8e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter TrbL PF04610.14 EGB09712.1 - 1.2 8.9 10.7 0.024 14.4 3.3 1.9 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein YpmT PF17431.2 EGB09712.1 - 3.3 7.8 6.5 1.7 8.7 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized YmpT-like DHHC PF01529.20 EGB09713.1 - 6.8e-30 103.9 1.2 8.2e-30 103.6 0.0 1.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase PAS_9 PF13426.7 EGB09714.1 - 4.3e-10 39.8 0.0 5.3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGB09714.1 - 5.5e-06 26.4 0.0 6.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGB09714.1 - 2.2e-05 24.7 0.0 2.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EGB09714.1 - 0.055 13.5 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 PAS domain TIP49_C PF17856.1 EGB09715.1 - 0.091 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 AAA-lid domain NOA36 PF06524.12 EGB09715.1 - 7.8 5.7 12.4 13 5.0 12.4 1.2 1 0 0 1 1 1 0 NOA36 protein DENN PF02141.21 EGB09716.1 - 3.7e-08 33.5 0.6 1e-07 32.1 0.6 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain PDZ PF00595.24 EGB09716.1 - 0.0065 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain FAD_binding_3 PF01494.19 EGB09717.1 - 1.4e-12 47.6 4.5 1.2e-10 41.2 4.5 3.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGB09717.1 - 2.5e-05 24.4 0.1 7.6e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB09717.1 - 0.00011 21.9 0.4 0.00011 21.9 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGB09717.1 - 0.00023 20.0 0.3 0.00032 19.5 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGB09717.1 - 0.0078 15.3 1.4 0.014 14.5 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB09717.1 - 0.021 14.1 0.2 0.036 13.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGB09717.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 EGB09717.1 - 0.034 13.4 0.1 0.057 12.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGB09717.1 - 0.061 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EGB09717.1 - 0.079 12.0 0.7 0.12 11.5 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGB09717.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGB09717.1 - 0.14 12.2 0.1 0.65 10.0 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_hydro_47 PF01532.20 EGB09718.1 - 6.3e-46 157.2 0.0 1.5e-45 156.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Syntaxin-6_N PF09177.11 EGB09718.1 - 6.4 7.4 13.7 30 5.2 8.7 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Rotamase PF00639.21 EGB09719.1 - 1.8e-18 67.3 0.0 2.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGB09719.1 - 2e-14 54.2 0.0 2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EGB09719.1 - 0.0007 20.4 0.0 0.00081 20.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain ASD1 PF08688.10 EGB09719.1 - 0.027 14.9 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 MCM PF00493.23 EGB09720.1 - 2.8e-101 337.3 0.4 4.3e-101 336.7 0.4 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGB09720.1 - 1.1e-38 132.0 0.1 1.9e-38 131.2 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGB09720.1 - 4.1e-26 91.2 0.6 7.9e-26 90.3 0.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGB09720.1 - 1.5e-10 41.5 0.0 3.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGB09720.1 - 1.5e-07 31.0 0.0 1.5e-06 27.7 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB09720.1 - 3.3e-06 27.1 0.0 3.3e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGB09720.1 - 9.8e-05 22.1 0.7 0.00091 19.0 0.1 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_lid_2 PF17863.1 EGB09720.1 - 0.0047 16.7 0.1 0.015 15.1 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 EGB09720.1 - 0.0073 16.2 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGB09721.1 - 2.3e-16 60.5 0.0 3.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGB09721.1 - 7.2e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 EGB09721.1 - 0.0014 18.5 0.0 0.054 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGB09721.1 - 0.0058 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB09721.1 - 0.0095 15.7 0.3 0.02 14.6 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGB09721.1 - 0.017 14.6 0.0 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGB09721.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EGB09721.1 - 0.027 14.1 2.2 0.052 13.1 0.3 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGB09721.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EGB09721.1 - 0.088 13.0 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB09721.1 - 0.13 12.4 0.5 0.46 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGB09721.1 - 0.33 11.4 0.1 0.56 10.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB09721.1 - 2.2 8.6 13.8 0.043 14.2 3.6 2.7 1 1 1 2 2 2 0 AAA ATPase domain Arylsulfotran_2 PF14269.6 EGB09722.1 - 1.1e-08 34.8 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EGB09722.1 - 8.2e-05 21.7 0.1 0.00018 20.5 0.1 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Methyltransf_24 PF13578.6 EGB09723.1 - 5.4e-07 30.6 0.7 1.8e-06 28.9 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain CmcI PF04989.12 EGB09723.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase FKBP_C PF00254.28 EGB09724.1 - 4.4e-26 91.0 0.0 6.5e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WD40 PF00400.32 EGB09725.1 - 2.2e-34 116.9 13.0 3.2e-07 30.9 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09725.1 - 3e-08 33.9 0.0 0.57 10.5 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB09725.1 - 0.0019 18.1 0.1 0.53 10.1 0.0 2.7 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGB09725.1 - 0.15 12.1 0.2 9.3 6.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGB09725.1 - 0.32 9.9 2.7 2.4 7.0 0.1 3.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DnaJ PF00226.31 EGB09726.1 - 9.8e-18 64.0 1.5 1.3e-17 63.7 1.5 1.1 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L6e PF01159.19 EGB09727.1 - 1.4e-37 128.6 0.0 1.8e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e Kin17_mid PF10357.9 EGB09728.1 - 1.8e-49 166.9 2.1 2.6e-49 166.3 2.1 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 EGB09728.1 - 7.2e-19 67.6 1.4 1.4e-18 66.7 1.4 1.5 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 EGB09728.1 - 0.0039 17.5 3.6 0.0075 16.6 3.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGB09728.1 - 0.011 16.0 2.5 0.019 15.3 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Fijivirus_P9-2 PF06837.11 EGB09728.1 - 0.23 10.9 0.5 0.42 10.0 0.3 1.4 1 1 0 1 1 1 0 Fijivirus P9-2 protein Cupin_4 PF08007.12 EGB09729.1 - 2.6e-17 63.3 0.0 3.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB09729.1 - 0.00039 20.1 0.0 0.0019 17.9 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EGB09729.1 - 0.044 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupin Arm PF00514.23 EGB09730.1 - 4.6e-15 55.0 47.0 0.00012 22.0 0.1 11.1 13 0 0 13 13 13 5 Armadillo/beta-catenin-like repeat TPR_1 PF00515.28 EGB09731.1 - 1.1e-27 94.6 23.3 3.2e-07 29.9 2.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGB09731.1 - 4.4e-24 82.6 22.6 1.3e-06 28.1 1.4 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB09731.1 - 9e-23 79.7 10.7 3e-08 33.2 0.1 5.2 3 1 2 5 5 5 4 TPR repeat TPR_14 PF13428.6 EGB09731.1 - 3.2e-17 61.8 5.3 0.0012 19.4 0.1 5.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09731.1 - 1.5e-15 57.5 7.5 3e-08 34.2 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09731.1 - 8.4e-15 53.7 14.5 2e-05 24.4 0.4 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09731.1 - 1.9e-13 50.7 10.3 9.5e-09 35.6 0.4 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGB09731.1 - 6.6e-12 44.6 2.3 0.05 13.7 0.1 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB09731.1 - 2e-11 44.0 10.1 0.00015 22.0 0.4 5.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGB09731.1 - 1.6e-08 34.4 15.4 2.8e-05 24.2 1.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat STI1 PF17830.1 EGB09731.1 - 3.3e-08 33.3 3.3 6.7e-08 32.4 2.3 2.1 2 0 0 2 2 2 1 STI1 domain Fis1_TPR_C PF14853.6 EGB09731.1 - 2.2e-07 30.8 2.4 0.019 15.0 0.2 3.6 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EGB09731.1 - 9.5e-06 25.3 7.0 0.0065 16.3 1.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 EGB09731.1 - 7.8e-05 23.1 4.5 0.0092 16.4 0.2 2.7 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_9 PF13371.6 EGB09731.1 - 0.00046 20.3 0.3 0.52 10.5 0.0 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB09731.1 - 0.0047 17.5 9.7 36 5.3 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGB09731.1 - 0.052 13.6 2.5 3.2 7.8 0.2 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 EGB09731.1 - 0.17 12.2 8.7 1 9.7 2.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGB09731.1 - 3 8.0 8.3 16 5.7 0.1 4.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF2868 PF11067.8 EGB09731.1 - 3.7 7.0 7.4 4.7 6.6 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Metal_resist PF13801.6 EGB09731.1 - 4.8 7.4 7.9 1.1 9.5 3.5 2.2 2 0 0 2 2 2 0 Heavy-metal resistance FPN1 PF06963.12 EGB09732.1 - 1e-36 126.5 6.3 1.3e-20 73.4 0.4 3.3 2 1 1 3 3 3 2 Ferroportin1 (FPN1) Glyco_transf_18 PF15024.6 EGB09732.1 - 3.9e-08 32.4 1.1 2.1e-06 26.7 0.2 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 18 zf-RING_2 PF13639.6 EGB09732.1 - 1.5e-06 28.4 6.1 1.5e-06 28.4 6.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB09732.1 - 6.2e-05 22.8 6.9 6.2e-05 22.8 6.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB09732.1 - 0.0015 18.8 3.7 0.0015 18.8 3.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGB09732.1 - 0.0016 18.1 8.1 0.0016 18.1 8.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGB09732.1 - 0.0044 17.0 3.2 0.012 15.7 3.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGB09732.1 - 0.053 13.4 7.9 0.0094 15.8 3.7 2.0 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) DUF2076 PF09849.9 EGB09732.1 - 0.057 13.5 4.3 0.29 11.2 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-ANAPC11 PF12861.7 EGB09732.1 - 0.61 10.2 4.4 1.9 8.6 4.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGB09732.1 - 5.1 6.8 13.5 0.071 12.7 5.2 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type ThiF PF00899.21 EGB09733.1 - 2.6e-27 95.8 0.0 1.8e-26 93.0 0.0 2.2 1 1 0 1 1 1 1 ThiF family OTU PF02338.19 EGB09733.1 - 1.7e-07 31.8 0.0 3.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF1295 PF06966.12 EGB09734.1 - 7.3e-13 48.6 0.1 9.6e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Peptidase_C2 PF00648.21 EGB09735.1 - 2.3e-24 86.0 0.0 1e-22 80.5 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease EF-hand_7 PF13499.6 EGB09735.1 - 0.00015 22.2 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair Pkinase PF00069.25 EGB09736.1 - 1.8e-44 152.1 0.0 2.3e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09736.1 - 3.2e-14 52.9 0.0 4.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB09736.1 - 0.0019 18.2 0.0 0.0096 15.9 0.0 2.1 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB09736.1 - 0.0045 16.3 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DHHC PF01529.20 EGB09737.1 - 3.1e-35 121.2 5.4 3.1e-35 121.2 5.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4190 PF13828.6 EGB09737.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Lipase_GDSL_2 PF13472.6 EGB09738.1 - 6.4e-05 23.4 0.7 0.00012 22.6 0.7 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PC-Esterase PF13839.6 EGB09738.1 - 0.17 11.6 0.1 18 4.9 0.1 2.3 2 1 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MGDG_synth PF06925.11 EGB09739.1 - 2.1e-24 86.5 0.0 2.6e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 EGB09739.1 - 1.9e-11 44.2 0.0 2.8e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 EGB09739.1 - 4.7e-06 26.2 0.0 6.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGB09739.1 - 4.6e-05 23.9 0.0 0.00014 22.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGB09739.1 - 0.0033 17.4 0.2 2.8 7.9 0.1 3.4 2 1 1 3 3 3 2 Glycosyltransferase Family 4 Smr PF01713.21 EGB09740.1 - 7.9e-06 26.1 0.0 2.7e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Smr domain DNA_ligase_A_M PF01068.21 EGB09741.1 - 5.3e-37 127.4 0.0 6.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 EGB09741.1 - 1.7e-16 60.6 0.0 3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Radial_spoke_3 PF06098.11 EGB09742.1 - 1.1e-73 248.0 0.0 1.3e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 Trypan_PARP PF05887.11 EGB09742.1 - 0.0016 18.4 16.3 0.0047 16.9 16.3 1.7 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) ICL PF00463.21 EGB09742.1 - 0.0075 14.8 0.5 0.01 14.4 0.5 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF4407 PF14362.6 EGB09742.1 - 0.26 10.6 4.6 0.39 10.0 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FoP_duplication PF13865.6 EGB09743.1 - 6.5e-19 68.3 15.1 6.5e-19 68.3 15.1 2.2 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Vac7 PF12751.7 EGB09743.1 - 0.3 10.5 1.8 0.32 10.4 1.8 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Baculo_PEP_C PF04513.12 EGB09745.1 - 9e-06 25.8 0.0 0.17 12.0 0.0 5.0 5 1 0 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus IL32 PF15225.6 EGB09745.1 - 7.9 6.9 5.3 6.3 7.2 0.2 3.1 3 0 0 3 3 3 0 Interleukin 32 zf-CCHC PF00098.23 EGB09746.1 - 1.2e-30 104.2 24.9 4.6e-10 39.1 3.1 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 EGB09746.1 - 1.2e-11 44.4 2.8 0.013 15.4 0.1 3.1 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 EGB09746.1 - 4.3e-08 32.7 13.8 0.029 14.1 0.6 3.1 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 EGB09746.1 - 0.01 15.6 19.6 0.52 10.2 2.0 3.5 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGB09746.1 - 0.014 15.2 20.7 0.97 9.3 1.0 3.2 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.6 EGB09746.1 - 0.038 13.7 12.4 3.1 7.6 0.6 3.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger TRAF6_Z2 PF18048.1 EGB09746.1 - 0.22 11.6 7.0 27 5.0 0.1 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 NinD PF17466.2 EGB09746.1 - 2.7 8.1 12.7 18 5.5 0.6 3.1 3 0 0 3 3 3 0 Family of unknown function Spt4 PF06093.13 EGB09746.1 - 3.8 7.7 6.5 68 3.7 0.1 3.1 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger IBR PF01485.21 EGB09746.1 - 5.3 7.4 8.4 62 3.9 0.1 3.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-C2HC_2 PF13913.6 EGB09746.1 - 9.2 6.3 9.9 45 4.1 0.2 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Complex1_51K PF01512.17 EGB09747.1 - 2.6e-49 167.0 0.0 3.8e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGB09747.1 - 1.9e-27 95.1 0.0 3.2e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGB09747.1 - 1.7e-08 34.2 0.0 3.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 SLBB domain Aldo_ket_red PF00248.21 EGB09748.1 - 2.4e-43 148.4 0.0 3.5e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_2 PF00152.20 EGB09749.1 - 1.6e-79 267.3 0.0 2.5e-79 266.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGB09749.1 - 1.6e-09 37.6 0.2 3.1e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LapA_dom PF06305.11 EGB09749.1 - 0.027 14.3 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AIRS_C PF02769.22 EGB09750.1 - 2.5e-25 89.4 2.4 5e-25 88.4 2.4 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Pyr_redox_2 PF07992.14 EGB09750.1 - 2.2e-20 73.1 0.1 3.4e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIRS PF00586.24 EGB09750.1 - 3.2e-13 50.1 3.7 1.6e-12 47.9 0.7 3.2 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Pyr_redox PF00070.27 EGB09750.1 - 6.4e-05 23.4 0.1 0.00017 22.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UQ_con PF00179.26 EGB09751.1 - 4.1e-47 159.4 0.0 4.9e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGB09751.1 - 0.00083 19.1 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGB09751.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 UEV domain WD40 PF00400.32 EGB09752.1 - 2e-08 34.7 0.8 0.0031 18.3 0.0 4.0 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09752.1 - 0.0012 19.2 0.0 1.3 9.4 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB09752.1 - 0.17 10.8 0.0 0.69 8.8 0.0 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein YEATS PF03366.16 EGB09753.1 - 1.5e-30 105.0 0.3 2.1e-30 104.5 0.3 1.2 1 0 0 1 1 1 1 YEATS family Dala_Dala_lig_C PF07478.13 EGB09754.1 - 2.1e-20 73.2 0.0 3.1e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 EGB09754.1 - 2.7e-19 69.6 0.0 7e-18 65.0 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 EGB09754.1 - 3.3e-06 26.8 0.0 0.094 12.3 0.1 2.2 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_D2 PF02786.17 EGB09754.1 - 0.0022 17.5 0.0 0.027 14.0 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain NnrU PF07298.11 EGB09755.1 - 6e-31 107.6 15.6 9.3e-31 107.0 15.6 1.2 1 0 0 1 1 1 1 NnrU protein ICMT PF04140.14 EGB09755.1 - 0.09 13.2 0.5 0.17 12.3 0.5 1.4 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family AfaD PF05775.12 EGB09755.1 - 0.097 13.1 0.4 0.73 10.3 0.0 2.3 2 0 0 2 2 2 0 Enterobacteria AfaD invasin protein Longin PF13774.6 EGB09756.1 - 1.3e-22 79.6 0.0 2.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGB09756.1 - 5.5e-18 64.5 0.6 5.1e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 Synaptobrevin DUF4661 PF15576.6 EGB09756.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Glyco_hydro_45 PF02015.16 EGB09757.1 - 5.3e-45 153.9 13.9 6e-45 153.7 13.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DPBB_1 PF03330.18 EGB09757.1 - 0.044 14.1 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Lytic transglycolase LRR_6 PF13516.6 EGB09758.1 - 6.5e-15 53.8 1.9 0.0012 18.7 0.0 4.0 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 EGB09758.1 - 8.8e-05 22.2 1.9 0.072 12.9 0.3 3.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 EGB09758.1 - 0.00011 22.3 0.0 7.1 7.6 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_4 PF12799.7 EGB09758.1 - 0.00042 20.7 0.0 0.014 15.8 0.0 2.5 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) Kinesin PF00225.23 EGB09759.1 - 6.9e-115 383.5 0.0 8.1e-115 383.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB09759.1 - 1.2e-27 96.7 0.0 2.6e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 EGB09759.1 - 0.0012 19.0 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 Kinesin-associated Tup_N PF08581.10 EGB09759.1 - 0.032 14.5 0.2 0.064 13.6 0.2 1.5 1 0 0 1 1 1 0 Tup N-terminal DUF1192 PF06698.11 EGB09759.1 - 0.036 14.1 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TSGA13 PF14994.6 EGB09759.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 Testis-specific gene 13 protein zf-ZPR1 PF03367.13 EGB09759.1 - 0.083 12.8 0.1 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 ZPR1 zinc-finger domain PIF1 PF05970.14 EGB09759.1 - 0.18 10.9 0.6 0.51 9.4 0.1 1.8 2 0 0 2 2 2 0 PIF1-like helicase zf-RING_2 PF13639.6 EGB09760.1 - 8.7e-14 51.6 2.2 1.6e-13 50.7 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB09760.1 - 1.8e-10 40.5 2.5 3.2e-10 39.7 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB09760.1 - 8.7e-10 38.7 1.3 1.7e-09 37.8 1.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGB09760.1 - 3.8e-09 36.1 0.6 7.1e-09 35.3 0.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGB09760.1 - 5.3e-09 35.8 1.0 8.8e-09 35.1 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB09760.1 - 1.4e-08 34.7 0.8 2.5e-08 33.8 0.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGB09760.1 - 1.5e-07 31.2 1.3 2.6e-07 30.5 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGB09760.1 - 1.1e-05 25.2 0.9 1.8e-05 24.5 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB09760.1 - 0.00023 20.9 2.2 0.00045 20.0 2.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGB09760.1 - 0.00024 21.1 0.6 0.00047 20.2 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EGB09760.1 - 0.00041 20.5 2.1 0.0011 19.1 2.1 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 EGB09760.1 - 0.0027 17.6 0.9 0.0027 17.6 0.9 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 EGB09760.1 - 0.013 15.7 1.6 0.025 14.8 1.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGB09760.1 - 0.019 14.7 2.1 0.043 13.6 2.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EGB09760.1 - 0.019 14.8 2.6 0.033 14.1 2.6 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 EGB09760.1 - 0.051 13.2 2.5 0.12 12.0 2.5 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EGB09760.1 - 0.12 12.5 2.9 0.24 11.5 2.9 1.5 1 0 0 1 1 1 0 RING-variant domain DUF1336 PF07059.12 EGB09761.1 - 7.8e-57 193.0 0.0 1.4e-56 192.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Sulfotransfer_3 PF13469.6 EGB09761.1 - 0.00035 21.0 0.0 0.0013 19.2 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family PAP_fibrillin PF04755.12 EGB09762.1 - 5.8e-24 85.1 0.0 6.8e-22 78.4 0.0 2.2 1 1 0 1 1 1 1 PAP_fibrillin IQ PF00612.27 EGB09762.1 - 0.73 9.8 9.6 1.2 9.1 2.6 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif PAP_fibrillin PF04755.12 EGB09763.1 - 8e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin Hydrolase_4 PF12146.8 EGB09763.1 - 9.5e-05 21.8 1.4 0.03 13.6 0.1 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGB09763.1 - 0.0016 19.1 6.2 0.0016 19.1 6.2 3.2 1 1 2 3 3 3 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EGB09763.1 - 0.1 12.2 0.1 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGB09763.1 - 0.1 12.3 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Dimer_Tnp_Tn5 PF02281.16 EGB09763.1 - 0.23 11.2 0.9 0.75 9.5 0.1 2.0 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain TilS PF09179.11 EGB09764.1 - 0.8 10.3 4.3 2 9.0 4.3 1.7 1 0 0 1 1 1 0 TilS substrate binding domain zf-C3HC4_3 PF13920.6 EGB09765.1 - 5.4e-15 55.0 11.1 1.3e-14 53.7 11.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Arm PF00514.23 EGB09765.1 - 3.8e-09 36.3 8.9 0.00064 19.7 0.3 4.8 3 1 0 3 3 3 2 Armadillo/beta-catenin-like repeat Myb_DNA-binding PF00249.31 EGB09765.1 - 5.7e-09 36.0 0.4 1e-08 35.2 0.4 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-RING_4 PF14447.6 EGB09765.1 - 1.1e-07 31.6 10.2 1.1e-07 31.6 10.2 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Myb_DNA-bind_6 PF13921.6 EGB09765.1 - 2.5e-06 27.6 0.2 4.6e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-RING_2 PF13639.6 EGB09765.1 - 0.00036 20.8 12.5 0.00036 20.8 12.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EGB09765.1 - 0.0013 18.6 10.0 0.0024 17.8 10.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Myb_DNA-bind_4 PF13837.6 EGB09765.1 - 0.022 15.1 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-C3HC4_2 PF13923.6 EGB09765.1 - 0.34 10.8 11.4 0.72 9.7 11.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 EGB09765.1 - 0.41 10.3 6.3 0.86 9.3 6.3 1.5 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 EGB09765.1 - 6 7.0 10.3 29 4.8 10.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon PhyH PF05721.13 EGB09766.1 - 7.3e-27 95.0 0.4 9.8e-27 94.6 0.4 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_31 PF13847.6 EGB09767.1 - 3.1e-28 98.5 0.0 4.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB09767.1 - 2.9e-20 72.8 0.1 7e-20 71.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09767.1 - 1.6e-19 70.4 0.2 3.1e-19 69.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB09767.1 - 1.3e-14 54.1 0.0 3.3e-14 52.8 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGB09767.1 - 1.2e-09 38.8 0.0 2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09767.1 - 2.1e-09 37.4 0.0 3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB09767.1 - 3.7e-06 26.9 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EGB09767.1 - 0.00021 20.8 0.1 0.00027 20.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 EGB09767.1 - 0.0017 18.2 0.1 0.0042 16.9 0.0 1.6 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 EGB09767.1 - 0.026 14.1 0.1 0.069 12.7 0.1 1.6 1 1 1 2 2 2 0 Methyltransferase small domain Met_10 PF02475.16 EGB09767.1 - 0.027 14.2 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 EGB09767.1 - 0.062 13.4 0.0 0.098 12.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EGB09767.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 EGB09767.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin UPF0020 PF01170.18 EGB09767.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CMAS PF02353.20 EGB09767.1 - 0.21 10.9 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 EGB09767.1 - 0.27 10.7 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 GCD14 PF08704.10 EGB09767.1 - 0.28 10.8 0.0 0.47 10.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ABC1 PF03109.16 EGB09768.1 - 3e-26 91.9 0.0 4.9e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB09768.1 - 0.00023 21.2 1.3 0.0022 17.9 1.1 2.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGB09768.1 - 0.0013 18.1 0.0 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 EGB09768.1 - 0.15 11.4 0.2 8.2 5.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Ion_trans PF00520.31 EGB09770.1 - 2e-06 27.2 0.1 4.9e-06 26.0 0.1 1.7 1 1 0 1 1 1 1 Ion transport protein DUF962 PF06127.11 EGB09770.1 - 0.65 10.1 3.1 0.82 9.8 1.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF962) RCC1 PF00415.18 EGB09771.1 - 1.7e-45 153.4 24.0 3.7e-14 53.1 1.0 7.3 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB09771.1 - 6.4e-18 64.1 53.9 2.5e-06 27.1 3.5 7.6 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat UBX PF00789.20 EGB09771.1 - 0.076 13.2 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 UBX domain Glyoxalase PF00903.25 EGB09772.1 - 7.3e-07 29.4 0.0 9.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGB09772.1 - 0.0012 19.1 0.0 0.0036 17.6 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGB09772.1 - 0.037 14.8 0.1 0.092 13.5 0.0 1.7 1 1 1 2 2 2 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EGB09772.1 - 0.079 13.1 0.0 0.59 10.2 0.0 2.0 1 1 1 2 2 2 0 Glyoxalase-like domain DUF2781 PF10914.8 EGB09773.1 - 6e-40 137.0 6.5 6.6e-40 136.9 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DnaJ PF00226.31 EGB09774.1 - 3.3e-14 52.7 0.0 6.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Snf7 PF03357.21 EGB09774.1 - 3.2e-05 23.6 0.0 6.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Snf7 MFS_5 PF05631.14 EGB09775.1 - 1.3e-72 244.7 4.1 1.6e-72 244.4 4.1 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGB09775.1 - 6.5e-15 54.9 23.4 9.7e-15 54.3 23.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 EGB09776.1 - 3.5e-144 480.6 0.0 4e-144 480.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 PhoLip_ATPase_C PF16212.5 EGB09777.1 - 7e-61 206.1 18.4 7e-61 206.1 18.4 2.1 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGB09777.1 - 3.4e-18 65.1 0.1 1.3e-17 63.2 0.1 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGB09777.1 - 5e-11 42.5 0.0 4.6e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGB09777.1 - 1.1e-10 41.3 0.0 3.6e-09 36.4 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGB09777.1 - 5.5e-05 23.5 10.5 0.035 14.4 6.8 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGB09777.1 - 0.0088 15.8 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Enolase_C PF00113.22 EGB09778.1 - 3.8e-132 440.0 0.0 4.7e-132 439.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGB09778.1 - 3.1e-57 192.4 0.0 5.1e-57 191.7 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGB09778.1 - 4.4e-05 23.2 0.0 7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGB09778.1 - 0.00022 20.5 0.2 0.00022 20.5 0.2 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus GCSF PF16647.5 EGB09778.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor Thiolase_N PF00108.23 EGB09779.1 - 3e-54 184.1 8.3 4.4e-54 183.6 8.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGB09779.1 - 3.7e-35 120.3 0.2 3.7e-35 120.3 0.2 2.5 3 1 1 4 4 4 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGB09779.1 - 0.032 13.8 6.8 0.27 10.7 5.1 2.5 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Sgf11_N PF18519.1 EGB09779.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain CbiX PF01903.17 EGB09779.1 - 0.1 13.0 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 CbiX zf-RanBP PF00641.18 EGB09780.1 - 5.8e-08 31.9 22.4 7.2e-06 25.2 7.5 2.2 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 EGB09780.1 - 0.0073 16.2 6.5 0.49 10.3 0.2 2.4 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 EGB09780.1 - 0.029 14.4 10.0 0.073 13.1 10.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 EGB09780.1 - 0.16 12.3 0.3 0.16 12.3 0.3 2.3 2 1 0 2 2 2 0 C1 domain Tudor_3 PF18115.1 EGB09781.1 - 1e-17 63.7 5.6 0.0013 18.5 0.0 6.5 6 0 0 6 6 6 5 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 EGB09781.1 - 1.4e-17 63.1 22.4 6.5e-05 22.6 0.4 7.4 8 0 0 8 8 8 4 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 EGB09781.1 - 2.4e-14 53.4 1.9 0.026 14.6 0.2 6.2 3 2 1 5 5 5 4 Domain of unknown function (DUF4537) Agenet PF05641.12 EGB09781.1 - 8.1e-13 48.6 11.0 0.031 14.7 0.1 8.1 8 0 0 8 8 8 3 Agenet domain DUF1325 PF07039.11 EGB09781.1 - 5e-11 42.8 0.0 0.11 12.6 0.0 5.3 3 1 2 5 5 5 3 SGF29 tudor-like domain LBR_tudor PF09465.10 EGB09781.1 - 6.6e-10 38.7 12.7 0.1 12.4 0.1 6.2 7 0 0 7 7 7 4 Lamin-B receptor of TUDOR domain 53-BP1_Tudor PF09038.10 EGB09781.1 - 4.2e-09 36.4 8.7 0.039 13.9 0.1 5.0 5 0 0 5 5 5 3 Tumour suppressor p53-binding protein-1 Tudor Trypan_PARP PF05887.11 EGB09781.1 - 2e-07 31.0 33.5 2e-07 31.0 33.5 2.2 2 0 0 2 2 1 1 Procyclic acidic repetitive protein (PARP) TUDOR PF00567.24 EGB09781.1 - 7.8e-05 22.7 0.2 3.6 7.6 0.0 4.4 3 1 1 4 4 4 2 Tudor domain T2SSM PF04612.12 EGB09781.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M PWWP PF00855.17 EGB09781.1 - 0.081 13.3 0.0 12 6.4 0.0 3.4 4 0 0 4 4 3 0 PWWP domain Tudor_2 PF18104.1 EGB09781.1 - 0.091 12.5 10.5 0.21 11.3 0.2 5.3 5 1 0 5 5 5 0 Jumonji domain-containing protein 2A Tudor domain CBM26 PF16738.5 EGB09781.1 - 0.3 11.4 3.3 5.1 7.4 0.1 3.2 4 0 0 4 4 3 0 Starch-binding module 26 Ribosomal_L13 PF00572.18 EGB09782.1 - 1.1e-48 164.6 0.1 1.3e-48 164.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Pre-PUA PF17832.1 EGB09783.1 - 6.6e-28 97.2 0.1 9.9e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGB09783.1 - 1.9e-08 34.1 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PUA domain Peptidase_S9 PF00326.21 EGB09784.1 - 3.4e-45 154.1 0.1 5.6e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGB09784.1 - 0.0013 18.1 0.2 0.0044 16.3 0.2 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1998 PF09369.10 EGB09784.1 - 0.15 12.9 0.0 26 5.6 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1998) SR-25 PF10500.9 EGB09784.1 - 0.26 10.9 23.3 0.42 10.2 23.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IGPD PF00475.18 EGB09785.1 - 1.4e-29 103.3 0.3 1.8e-29 102.9 0.3 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase peroxidase PF00141.23 EGB09787.1 - 1.1e-20 74.3 0.0 1.3e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase Herpes_UL25 PF01499.16 EGB09788.1 - 3 6.3 10.7 4.6 5.6 10.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF724 PF05266.14 EGB09788.1 - 3.8 7.3 7.2 29 4.4 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Sel1 PF08238.12 EGB09789.1 - 2e-49 164.9 31.1 4.9e-08 33.4 0.7 9.2 9 0 0 9 9 9 9 Sel1 repeat TPR_7 PF13176.6 EGB09789.1 - 0.0021 17.9 9.6 0.084 12.9 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF410 PF04190.13 EGB09789.1 - 0.02 14.7 0.5 6.7 6.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF410) TPR_12 PF13424.6 EGB09789.1 - 0.06 13.6 0.6 0.06 13.6 0.6 6.1 7 2 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09789.1 - 0.2 11.5 0.1 0.2 11.5 0.1 7.1 10 0 0 10 10 10 0 Tetratricopeptide repeat PSD5 PF07637.11 EGB09789.1 - 0.33 11.3 3.7 33 4.9 0.1 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1595) MIT PF04212.18 EGB09789.1 - 1.2 9.3 13.0 1.2 9.2 0.3 5.5 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain HOOK PF05622.12 EGB09790.1 - 3.6e-16 58.5 24.2 1.3e-15 56.7 24.2 2.0 1 1 0 1 1 1 1 HOOK protein STAT_alpha PF01017.20 EGB09790.1 - 0.22 11.4 5.8 1.3 8.9 0.8 3.1 3 0 0 3 3 3 0 STAT protein, all-alpha domain Lectin_N PF03954.14 EGB09790.1 - 0.94 9.2 5.3 0.54 10.0 0.3 2.9 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain BLOC1_2 PF10046.9 EGB09790.1 - 1.3 9.4 14.7 3.7 7.9 0.2 4.4 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRAF_BIRC3_bd PF16673.5 EGB09790.1 - 1.9 8.3 6.4 0.67 9.8 0.8 3.2 3 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain FAM76 PF16046.5 EGB09790.1 - 2 7.7 12.5 0.38 10.1 3.1 2.6 2 1 0 2 2 2 0 FAM76 protein Atg14 PF10186.9 EGB09790.1 - 5.9 5.9 21.4 0.37 9.8 1.5 3.3 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Glyco_transf_10 PF00852.19 EGB09791.1 - 6.8e-35 120.4 0.0 8.5e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term RSN1_7TM PF02714.15 EGB09792.1 - 6.1e-46 156.9 0.4 8.4e-46 156.5 0.4 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGB09792.1 - 1.4e-17 63.9 0.0 2.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport HMG_box PF00505.19 EGB09792.1 - 1.7e-07 31.5 1.2 3.5e-07 30.5 1.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box PHM7_cyt PF14703.6 EGB09792.1 - 1.2e-06 28.9 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter HMG_box_2 PF09011.10 EGB09792.1 - 0.012 16.2 2.6 0.012 16.2 2.6 1.8 2 0 0 2 2 2 0 HMG-box domain DUF755 PF05501.11 EGB09792.1 - 6.2 7.1 12.4 13 6.1 12.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Caskin-Pro-rich PF16907.5 EGB09792.1 - 9.4 6.8 15.4 0.52 10.9 6.8 3.0 3 0 0 3 3 3 0 Proline rich region of Caskin proteins ACT_6 PF13740.6 EGB09793.1 - 2e-11 43.7 0.1 2e-06 27.7 0.0 3.4 3 0 0 3 3 3 2 ACT domain Mpv17_PMP22 PF04117.12 EGB09793.1 - 2.3e-10 40.6 2.4 4.4e-10 39.6 2.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ACT PF01842.25 EGB09793.1 - 1.2e-06 28.1 0.1 0.00071 19.3 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 EGB09793.1 - 6.3e-05 23.5 0.0 0.29 11.8 0.0 2.4 2 0 0 2 2 2 2 ACT domain Pro_isomerase PF00160.21 EGB09794.1 - 1.3e-43 149.0 0.0 4e-43 147.4 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 EGB09794.1 - 8.1e-10 38.5 0.0 2.6e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EGB09794.1 - 0.02 15.0 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Kinesin PF00225.23 EGB09795.1 - 2.2e-47 161.6 0.0 5.2e-47 160.4 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB09795.1 - 0.00025 21.0 0.0 0.00066 19.6 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding SAM_3 PF18016.1 EGB09795.1 - 0.00083 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_16 PF13191.6 EGB09795.1 - 0.013 15.9 1.3 0.013 15.9 1.3 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGB09795.1 - 0.054 13.8 0.5 0.34 11.2 0.0 2.5 2 1 0 3 3 3 0 AAA domain Pkinase PF00069.25 EGB09796.1 - 6.9e-30 104.3 0.0 7.6e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09796.1 - 1.1e-08 34.7 0.0 1.3e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB09796.1 - 0.02 14.8 1.0 0.041 13.8 0.8 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB09796.1 - 0.19 10.5 0.0 0.23 10.2 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 EGB09797.1 - 2.5e-20 72.9 0.3 1.3e-11 44.9 0.1 3.5 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB09797.1 - 1.1e-09 38.3 0.4 9.3e-08 32.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB09797.1 - 3.3e-09 37.1 0.0 0.001 19.6 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB09797.1 - 4.1e-07 29.8 0.0 0.17 12.5 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EGB09797.1 - 1.9e-06 28.0 0.2 0.067 13.7 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Neur_chan_LBD PF02931.23 EGB09798.1 - 1.1e-23 83.8 0.0 1.7e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain APH PF01636.23 EGB09798.1 - 2.3e-11 44.1 1.0 2.3e-11 44.1 1.0 12.9 9 4 1 12 12 12 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGB09798.1 - 1.6e-05 24.4 0.0 7.1e-05 22.3 0.0 2.0 2 1 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 EGB09798.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Filament PF00038.21 EGB09798.1 - 2.6 7.5 35.8 8.5 5.9 35.8 1.7 1 1 0 1 1 1 0 Intermediate filament protein FCSD-flav_bind PF09242.11 EGB09799.1 - 0.18 12.2 0.6 0.68 10.3 0.6 2.0 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding Anoctamin PF04547.12 EGB09800.1 - 9.4e-79 265.3 7.1 1.1e-78 265.0 7.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF4131 PF13567.6 EGB09800.1 - 0.12 12.0 0.1 6.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Prenyltrans PF00432.21 EGB09801.1 - 2.5e-42 142.3 19.8 3.9e-10 39.3 0.0 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat PsbU PF06514.11 EGB09802.1 - 4.8e-18 64.9 0.0 9.7e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) DUF389 PF04087.14 EGB09802.1 - 0.032 14.3 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF389) HHH_3 PF12836.7 EGB09802.1 - 0.034 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1345 PF07077.11 EGB09803.1 - 0.0009 19.0 2.6 0.0067 16.1 0.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1345) WD40 PF00400.32 EGB09804.1 - 3.3e-08 34.1 5.8 2.7 9.0 0.0 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Ephrin_rec_like PF07699.13 EGB09805.1 - 9.8e-18 63.7 48.8 1.3e-05 24.8 6.6 4.6 1 1 3 4 4 4 4 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB09805.1 - 0.0077 16.6 43.0 0.97 9.9 0.1 6.4 1 1 6 7 7 7 6 TNFR/NGFR cysteine-rich region zf-ACC PF17848.1 EGB09805.1 - 0.64 10.1 0.0 0.64 10.1 0.0 5.9 6 2 0 6 6 6 0 Acetyl-coA carboxylase zinc finger domain cNMP_binding PF00027.29 EGB09806.1 - 1.2e-15 57.3 0.0 4.1e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain KN17_SH3 PF18131.1 EGB09806.1 - 0.043 13.9 0.1 0.48 10.6 0.1 2.2 2 0 0 2 2 2 0 KN17 SH3-like C-terminal domain CCDC106 PF15794.5 EGB09806.1 - 0.52 10.0 3.6 2.2 7.9 3.6 2.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Peptidase_S49 PF01343.18 EGB09807.1 - 3.1e-33 114.9 0.0 4.5e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 EGB09807.1 - 3.6e-08 33.6 0.0 7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S49 N-terminal P34-Arc PF04045.14 EGB09808.1 - 8.8e-73 244.9 0.0 1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc CMAS PF02353.20 EGB09809.1 - 5.1e-66 222.8 0.0 6.2e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGB09809.1 - 2.3e-12 47.4 0.0 4.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB09809.1 - 9.7e-12 45.0 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB09809.1 - 3.9e-08 33.8 0.0 9.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB09809.1 - 7.6e-08 33.0 0.0 1.7e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB09809.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EGB09809.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MTS PF05175.14 EGB09809.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 EGB09809.1 - 0.025 14.7 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.20 EGB09809.1 - 0.038 13.0 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Spermine_synth PF01564.17 EGB09809.1 - 0.055 12.9 0.1 0.09 12.2 0.1 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain GCD14 PF08704.10 EGB09809.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit L-fibroin PF05849.11 EGB09809.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) Adaptin_N PF01602.20 EGB09810.1 - 7.2e-86 288.8 0.0 1e-85 288.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGB09810.1 - 2.2e-39 135.1 0.0 1.1e-37 129.5 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGB09810.1 - 1.3e-11 44.7 7.2 0.022 15.1 5.3 4.4 2 2 2 5 5 5 5 HEAT repeats RTP1_C1 PF10363.9 EGB09810.1 - 0.055 13.7 0.0 14 5.9 0.0 3.4 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EGB09810.1 - 0.065 13.5 11.1 32 5.2 0.2 6.8 8 0 0 8 8 8 0 HEAT repeat HRDC PF00570.23 EGB09811.1 - 6.8e-18 64.4 0.0 1.9e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.31 EGB09811.1 - 3.7e-14 53.0 0.0 4e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB09811.1 - 2.6e-12 47.1 0.0 2.1e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrB PF12344.8 EGB09811.1 - 2.3e-10 40.1 0.0 5.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Ultra-violet resistance protein B DEAD PF00270.29 EGB09811.1 - 8.9e-07 28.8 0.0 1.3e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGB09811.1 - 8.4e-05 22.4 4.0 0.00026 20.8 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EGB09811.1 - 0.0007 20.0 2.0 0.0055 17.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain TsaE PF02367.17 EGB09811.1 - 0.002 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EGB09811.1 - 0.0055 17.0 0.2 0.029 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGB09811.1 - 0.006 16.9 2.7 0.12 12.7 0.0 2.9 3 1 0 3 3 2 1 AAA domain HHH PF00633.23 EGB09811.1 - 0.029 14.3 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif AAA_7 PF12775.7 EGB09811.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGB09811.1 - 0.029 14.5 0.3 0.26 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 EGB09811.1 - 0.043 13.0 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.14 EGB09811.1 - 0.054 13.5 0.3 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EGB09811.1 - 0.082 12.1 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NAD_kinase PF01513.21 EGB09812.1 - 1.3e-49 168.9 0.0 2.6e-49 168.0 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase eIF-1a PF01176.19 EGB09812.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 ABC_tran PF00005.27 EGB09813.1 - 3.7e-17 63.1 0.0 7.1e-17 62.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB09813.1 - 2.1e-06 27.8 0.1 0.0063 16.4 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB09813.1 - 0.00095 19.6 0.2 0.0017 18.8 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGB09813.1 - 0.0013 18.3 0.2 0.0023 17.5 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB09813.1 - 0.0034 17.7 0.0 0.0071 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB09813.1 - 0.0065 16.2 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EGB09813.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB09813.1 - 0.016 15.2 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 EGB09813.1 - 0.022 15.3 0.1 0.032 14.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGB09813.1 - 0.031 14.8 0.0 0.048 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB09813.1 - 0.089 12.7 0.2 0.17 11.8 0.1 1.4 1 1 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 EGB09813.1 - 0.094 12.1 0.0 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 EGB09813.1 - 0.098 12.2 0.3 0.19 11.3 0.3 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 EGB09813.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGB09813.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 EGB09813.1 - 0.26 11.3 0.2 0.48 10.4 0.2 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DegT_DnrJ_EryC1 PF01041.17 EGB09814.1 - 4.3e-83 279.6 0.7 5.2e-83 279.3 0.7 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGB09814.1 - 0.053 12.7 0.1 0.079 12.1 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Isochorismatase PF00857.20 EGB09815.1 - 4.3e-34 118.2 0.0 5.6e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Dak2 PF02734.17 EGB09816.1 - 8.4e-37 126.7 13.6 8.4e-37 126.7 13.6 2.2 2 1 1 3 3 3 1 DAK2 domain Dak1 PF02733.17 EGB09816.1 - 1.5e-09 37.2 0.0 2.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Glycos_transf_2 PF00535.26 EGB09817.1 - 9.7e-09 35.3 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB09817.1 - 1.9e-06 27.9 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Alpha_kinase PF02816.18 EGB09818.1 - 4.5e-17 62.8 0.0 7.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family zf-C3HC4_3 PF13920.6 EGB09818.1 - 1.2e-11 44.3 5.4 2e-11 43.5 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB09818.1 - 4.8e-07 29.5 5.7 1.4e-06 28.1 6.0 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGB09818.1 - 2.5e-06 27.2 8.8 4.8e-06 26.3 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB09818.1 - 3e-05 23.9 8.1 9.9e-05 22.2 8.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGB09818.1 - 4.5e-05 23.7 7.6 9.4e-05 22.7 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGB09818.1 - 8.9e-05 22.3 4.3 0.00021 21.1 4.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB09818.1 - 0.00017 21.5 7.4 0.00045 20.2 7.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGB09818.1 - 0.0021 18.2 4.5 0.0066 16.6 4.5 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Strep_SA_rep PF06696.11 EGB09818.1 - 0.2 11.7 1.7 0.67 10.0 0.2 2.3 1 1 1 2 2 2 0 Streptococcal surface antigen repeat zf-RING_4 PF14570.6 EGB09818.1 - 1 9.2 6.9 3.3 7.6 7.0 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2187 PF09953.9 EGB09818.1 - 1.4 9.0 3.2 14 5.7 1.3 3.3 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) DUF4604 PF15377.6 EGB09818.1 - 3.2 8.2 6.9 5.3 7.4 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) zf-C3H2C3 PF17122.5 EGB09818.1 - 7.8 6.6 12.1 0.39 10.8 5.9 2.0 2 0 0 2 2 2 0 Zinc-finger SET PF00856.28 EGB09819.1 - 6.8e-17 62.4 0.0 9.3e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EGB09819.1 - 0.0048 16.9 7.4 0.0048 16.9 7.4 3.4 5 0 0 5 5 5 1 AWS domain Ank_4 PF13637.6 EGB09821.1 - 1.9e-23 82.5 0.2 6.9e-08 32.9 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB09821.1 - 1.8e-21 76.5 0.0 1.2e-10 41.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB09821.1 - 4.6e-19 68.2 2.5 2.3e-10 40.5 0.1 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB09821.1 - 5.9e-19 67.6 0.6 5e-08 33.0 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EGB09821.1 - 1.1e-13 50.0 0.0 0.00026 21.2 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Pkinase PF00069.25 EGB09822.1 - 8.1e-44 150.0 0.0 9.9e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09822.1 - 6e-43 147.0 0.0 8.4e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB09822.1 - 0.00078 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB09822.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ILEI PF15711.5 EGB09823.1 - 4.2e-13 49.6 0.0 1.1e-12 48.2 0.0 1.7 2 0 0 2 2 2 1 Interleukin-like EMT inducer TUDOR_5 PF18359.1 EGB09823.1 - 0.00081 19.0 1.3 0.0025 17.5 0.8 2.2 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 SR-25 PF10500.9 EGB09823.1 - 0.026 14.1 15.8 0.047 13.3 15.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1325 PF07039.11 EGB09823.1 - 0.049 13.7 0.0 2.8 8.0 0.0 2.7 2 0 0 2 2 2 0 SGF29 tudor-like domain Agenet PF05641.12 EGB09823.1 - 0.053 14.0 2.9 0.25 11.8 0.1 2.9 3 0 0 3 3 3 0 Agenet domain LBR_tudor PF09465.10 EGB09823.1 - 0.06 13.2 0.2 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DDHD PF02862.17 EGB09823.1 - 0.22 11.6 1.4 3.3 7.8 1.3 2.2 2 0 0 2 2 2 0 DDHD domain PPP4R2 PF09184.11 EGB09823.1 - 0.45 10.1 7.8 2.3 7.7 7.2 2.0 2 0 0 2 2 2 0 PPP4R2 Cwf_Cwc_15 PF04889.12 EGB09823.1 - 4.3 7.0 18.4 7.1 6.3 18.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ABC_tran PF00005.27 EGB09824.1 - 8.4e-24 84.6 0.0 1.1e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB09824.1 - 4.2e-10 39.9 0.7 9.1e-07 29.0 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB09824.1 - 0.00026 20.5 0.0 0.052 13.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGB09824.1 - 0.00043 20.9 0.0 0.00072 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB09824.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EGB09824.1 - 0.011 15.5 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EGB09824.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 EGB09824.1 - 0.061 13.6 0.1 0.85 9.9 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EGB09825.1 - 1.7e-25 90.1 0.0 2.2e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB09825.1 - 1.1e-14 54.9 0.0 2.4e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGB09825.1 - 0.0025 17.6 0.0 0.048 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MukB PF04310.12 EGB09825.1 - 0.0061 16.4 0.3 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 MukB N-terminal AAA_23 PF13476.6 EGB09825.1 - 0.0073 16.8 0.0 0.0097 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB09825.1 - 0.013 15.2 3.3 0.034 13.8 3.0 2.1 1 1 1 2 2 2 0 AAA domain SMC_N PF02463.19 EGB09825.1 - 0.044 13.2 0.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGB09825.1 - 0.057 13.7 0.0 0.44 10.8 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGB09825.1 - 0.064 13.0 0.3 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 EGB09825.1 - 0.068 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 EGB09825.1 - 0.16 11.7 0.0 18 5.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Glyco_hydro_38N PF01074.22 EGB09826.1 - 5.3e-69 232.8 10.8 7e-69 232.4 10.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGB09826.1 - 3.1e-31 109.1 0.0 4.9e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGB09826.1 - 1.4e-14 54.0 0.0 4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Chloroa_b-bind PF00504.21 EGB09827.1 - 8.8e-32 110.9 0.2 1.1e-31 110.5 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TACC_C PF05010.14 EGB09828.1 - 0.24 11.2 5.0 0.38 10.5 5.0 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF572 PF04502.13 EGB09828.1 - 1.2 8.6 5.0 1.4 8.5 5.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Radical_SAM PF04055.21 EGB09830.1 - 2.7e-15 57.2 0.0 4.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EGB09830.1 - 8.9e-05 22.6 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EGB09830.1 - 0.013 15.8 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain cNMP_binding PF00027.29 EGB09831.1 - 1.4e-37 127.7 0.0 2.1e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 EGB09831.1 - 0.065 13.0 0.0 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 Cupin domain zf-C2HC_2 PF13913.6 EGB09832.1 - 2.5e-16 59.1 8.1 1.1e-09 37.9 1.9 2.2 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 EGB09832.1 - 0.00028 21.2 0.3 0.23 12.0 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGB09832.1 - 0.012 16.3 4.3 0.18 12.8 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 EGB09832.1 - 0.048 13.6 2.2 10 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Rad50_zn_hook PF04423.14 EGB09832.1 - 0.089 12.6 0.2 5.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_recom PF13408.6 EGB09832.1 - 0.092 13.3 0.5 18 5.9 0.1 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Prok-RING_1 PF14446.6 EGB09832.1 - 0.11 12.5 0.8 6.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 EGB09832.1 - 0.12 12.7 2.7 1.2 9.5 0.7 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2256 PF10013.9 EGB09832.1 - 0.13 12.4 2.6 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) YacG PF03884.14 EGB09832.1 - 0.76 9.6 3.6 0.33 10.7 1.1 1.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG ADK_lid PF05191.14 EGB09832.1 - 1.4 9.0 6.6 0.22 11.5 0.9 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid CAP_N PF01213.19 EGB09832.1 - 4.3 6.7 8.2 0.16 11.4 2.5 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sgf11 PF08209.11 EGB09832.1 - 7.2 6.3 10.1 5.4 6.7 0.7 2.7 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pkinase PF00069.25 EGB09833.1 - 1.9e-42 145.5 0.1 7.4e-42 143.5 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09833.1 - 7.3e-25 87.7 0.0 4.4e-24 85.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGB09833.1 - 0.00037 20.5 0.1 0.0085 16.0 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB09833.1 - 0.011 15.3 0.5 0.027 14.1 0.5 1.6 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EGB09833.1 - 0.016 14.0 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EGB09833.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 EGB09833.1 - 0.03 13.6 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EGB09833.1 - 0.034 13.8 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGB09833.1 - 0.039 13.3 1.0 0.057 12.8 0.4 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGB09833.1 - 0.18 11.4 0.2 0.35 10.4 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Chloroa_b-bind PF00504.21 EGB09834.1 - 9.1e-37 127.1 0.1 1.1e-36 126.8 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein AAA_34 PF13872.6 EGB09835.1 - 1.3e-113 378.9 0.0 1.8e-113 378.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 EGB09835.1 - 1.3e-89 300.5 0.6 2.1e-88 296.6 0.6 2.2 1 1 0 1 1 1 1 C-terminal domain on Strawberry notch homologue Shugoshin_C PF07557.11 EGB09835.1 - 4.1e-08 32.9 3.5 1e-07 31.6 3.5 1.7 1 0 0 1 1 1 1 Shugoshin C terminus ResIII PF04851.15 EGB09835.1 - 2.5e-05 24.4 0.0 4.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RanBP PF00641.18 EGB09835.1 - 0.00067 18.9 1.7 0.0016 17.7 1.7 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others CH PF00307.31 EGB09836.1 - 4.2e-19 68.7 0.0 4.7e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGB09836.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain 4HBT_3 PF13622.6 EGB09838.1 - 2e-24 87.2 0.2 2.4e-24 87.0 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EGB09838.1 - 0.0034 17.2 0.0 0.024 14.5 0.0 1.9 1 1 1 2 2 2 1 Acyl-CoA thioesterase Ank_2 PF12796.7 EGB09840.1 - 0.0012 19.4 0.0 0.0019 18.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09840.1 - 0.063 13.9 0.1 8.4 7.3 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat DUF4440 PF14534.6 EGB09841.1 - 0.0007 20.0 0.7 0.0071 16.7 0.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Cofilin_ADF PF00241.20 EGB09844.1 - 5.5e-20 71.4 0.0 1.9e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Kinesin PF00225.23 EGB09845.1 - 5.7e-89 298.3 0.0 7.1e-89 298.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB09845.1 - 2.8e-30 105.2 0.0 4.3e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding EF-hand_6 PF13405.6 EGB09846.1 - 2.8e-11 42.4 5.5 6.9e-05 22.5 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGB09846.1 - 5.8e-11 41.1 3.8 0.0002 20.7 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB09846.1 - 6.1e-10 39.4 0.1 4.7e-09 36.6 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB09846.1 - 1.5e-08 33.8 1.7 0.0014 18.1 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB09846.1 - 2.8e-06 27.1 0.8 0.019 14.8 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB09848.1 - 9.2e-43 140.5 26.0 9e-07 28.3 0.1 9.7 9 1 0 9 9 9 8 EF-hand domain EF-hand_1 PF00036.32 EGB09848.1 - 1.1e-41 137.3 22.1 7.7e-06 25.1 0.1 9.2 10 0 0 10 10 10 8 EF hand EF-hand_7 PF13499.6 EGB09848.1 - 2.5e-40 136.8 16.9 1.3e-09 38.4 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_8 PF13833.6 EGB09848.1 - 1.9e-22 78.9 20.3 1.1e-06 28.3 0.0 8.3 5 3 3 8 8 8 6 EF-hand domain pair EF-hand_5 PF13202.6 EGB09848.1 - 4.1e-22 76.6 31.7 1.9e-05 23.9 0.0 8.7 9 0 0 9 9 9 6 EF hand EF-hand_9 PF14658.6 EGB09848.1 - 9.4e-15 54.7 1.7 0.0029 17.9 0.1 5.0 5 0 0 5 5 5 3 EF-hand domain Caleosin PF05042.13 EGB09848.1 - 2.4e-05 24.3 0.5 0.11 12.4 0.0 5.0 3 2 3 6 6 6 1 Caleosin related protein EF-hand_14 PF17959.1 EGB09848.1 - 0.0067 16.8 0.5 38 4.7 0.0 4.9 5 0 0 5 5 5 0 EF-hand domain Toprim_2 PF13155.6 EGB09848.1 - 0.01 16.3 1.0 8.1 7.0 0.0 4.0 4 0 0 4 4 4 0 Toprim-like GCV_T PF01571.21 EGB09849.1 - 2.5e-10 40.2 0.1 3.6e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain F-box PF00646.33 EGB09850.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EGB09850.1 - 0.024 14.5 0.1 0.056 13.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 EGB09850.1 - 0.058 13.5 16.5 0.06 13.4 1.4 4.6 5 0 0 5 5 5 0 Leucine Rich repeat DUF572 PF04502.13 EGB09850.1 - 0.25 10.9 17.8 0.25 10.9 7.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) LRR_1 PF00560.33 EGB09850.1 - 0.61 10.9 6.6 31 5.7 0.5 4.1 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 EGB09850.1 - 5 7.7 12.2 0.68 10.4 0.6 3.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB09850.1 - 9.5 6.1 11.1 2 8.2 1.9 3.4 2 1 1 3 3 3 0 Leucine rich repeat Fringe PF02434.16 EGB09852.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Pkinase PF00069.25 EGB09853.1 - 4.9e-76 255.6 0.0 5.8e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB09853.1 - 7.1e-32 110.7 0.0 9e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB09853.1 - 0.019 14.3 0.2 0.035 13.5 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB09853.1 - 0.02 14.8 1.2 0.29 11.0 0.7 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.19 EGB09854.1 - 2e-90 303.4 0.0 1e-88 297.7 0.0 2.0 1 1 0 1 1 1 1 Actin NifU PF01106.17 EGB09855.1 - 3.9e-29 100.6 0.4 1.2e-24 86.2 0.1 2.0 2 0 0 2 2 2 2 NifU-like domain ATP-grasp_4 PF13535.6 EGB09856.1 - 1.4e-11 44.3 0.0 2.4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGB09856.1 - 3.5e-09 36.9 0.0 5.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGB09856.1 - 0.0015 18.3 0.0 0.0053 16.5 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GSH-S_ATP PF02955.16 EGB09856.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_Ter PF15632.6 EGB09856.1 - 0.0099 15.6 0.0 0.059 13.1 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon DUF5020 PF16412.5 EGB09856.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) ATPgrasp_YheCD PF14398.6 EGB09856.1 - 0.038 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp Abhydrolase_6 PF12697.7 EGB09857.1 - 3.6e-05 24.5 8.3 5.9e-05 23.8 8.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGB09857.1 - 0.00026 20.3 0.0 0.0009 18.6 0.0 1.9 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGB09857.1 - 0.0017 17.3 0.0 0.0039 16.1 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 EGB09857.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 EGB09857.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 EGB09857.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EGB09857.1 - 0.061 12.9 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EGB09857.1 - 0.083 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 EGB09857.1 - 0.085 11.5 0.1 8.8 4.9 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Beta-lactamase PF00144.24 EGB09858.1 - 1.4e-25 90.3 0.2 5.6e-25 88.3 0.2 1.9 1 1 0 1 1 1 1 Beta-lactamase PrmA PF06325.13 EGB09858.1 - 0.00032 20.2 0.1 0.00052 19.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EGB09858.1 - 0.004 16.9 0.0 0.058 13.1 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase CLP1_P PF16575.5 EGB09858.1 - 0.05 13.4 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop LysM PF01476.20 EGB09859.1 - 0.00039 20.4 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain RcnB PF11776.8 EGB09859.1 - 0.003 17.6 0.1 0.0071 16.4 0.1 1.7 1 0 0 1 1 1 1 Nickel/cobalt transporter regulator CRT10 PF08728.10 EGB09860.1 - 0.36 8.9 7.5 0.6 8.2 7.5 1.2 1 0 0 1 1 1 0 CRT10 HALZ PF02183.18 EGB09860.1 - 1.1 9.5 5.7 9.4 6.5 0.6 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper PI_PP_C PF18365.1 EGB09860.1 - 1.4 8.9 5.3 22 5.0 1.0 3.0 2 1 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain PDH PF02153.17 EGB09863.1 - 4.5e-17 61.9 0.0 6e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EGB09863.1 - 4.1e-08 33.7 0.0 7.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 EGB09863.1 - 0.00043 20.2 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 Rossmann-like domain 2-Hacid_dh_C PF02826.19 EGB09863.1 - 0.00097 18.5 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGB09863.1 - 0.0085 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGB09863.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EGB09863.1 - 0.02 15.1 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 EGB09863.1 - 0.041 14.7 0.0 0.18 12.6 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EGB09863.1 - 0.082 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 EGB09863.1 - 0.089 12.8 0.0 0.89 9.5 0.0 2.4 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Gp_dh_N PF00044.24 EGB09863.1 - 0.1 12.9 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF952 PF06108.12 EGB09864.1 - 7.8e-14 51.5 0.0 1.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF952) AraC_binding_2 PF14525.6 EGB09864.1 - 4e-05 23.4 0.0 7.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AraC-binding-like domain Cupin_3 PF05899.12 EGB09864.1 - 0.00038 20.1 0.2 0.00091 18.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EGB09864.1 - 0.0007 19.3 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Pilin_GH PF16734.5 EGB09864.1 - 0.059 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative DUF1471 PF07338.13 EGB09864.1 - 0.19 11.7 0.8 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Sulfatase PF00884.23 EGB09865.1 - 5.7e-46 157.3 0.0 8e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB09865.1 - 5e-07 29.6 0.2 1.2e-06 28.3 0.2 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGB09865.1 - 0.08 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.24 EGB09866.1 - 2.8e-61 207.8 23.8 3.2e-40 138.4 4.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGB09866.1 - 2.6e-09 36.5 31.1 2.6e-09 36.5 31.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_C69 PF03577.15 EGB09867.1 - 1.8e-21 76.5 0.0 6.8e-21 74.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C69 DUF4795 PF16043.5 EGB09868.1 - 0.11 12.1 21.0 0.14 11.8 1.9 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4795) BLOC1_2 PF10046.9 EGB09868.1 - 0.2 12.0 16.9 8.6 6.7 1.2 6.8 5 3 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.20 EGB09868.1 - 0.29 11.1 2.9 0.98 9.4 0.5 3.4 2 1 0 2 2 2 0 Prefoldin subunit EAP30 PF04157.16 EGB09868.1 - 0.31 10.3 9.7 0.59 9.4 1.0 3.6 3 0 0 3 3 3 0 EAP30/Vps36 family Jnk-SapK_ap_N PF09744.9 EGB09868.1 - 2.4 8.4 37.2 0.72 10.1 0.4 6.5 5 2 1 6 6 6 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 EGB09868.1 - 2.7 8.0 16.5 3.1 7.8 1.2 5.8 6 2 1 7 7 7 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EGB09868.1 - 4.2 6.2 31.6 0.44 9.4 6.4 4.5 4 0 0 4 4 4 0 Spc7 kinetochore protein SPX PF03105.19 EGB09869.1 - 7e-05 22.9 0.0 0.0002 21.4 0.0 1.6 2 0 0 2 2 2 1 SPX domain DNA_processg_A PF02481.15 EGB09870.1 - 0.00019 20.8 0.1 0.00021 20.6 0.1 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A polyprenyl_synt PF00348.17 EGB09871.1 - 7.9e-62 208.6 1.0 9.7e-62 208.3 1.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EGB09871.1 - 0.049 13.2 0.5 0.075 12.6 0.5 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Pro_isomerase PF00160.21 EGB09873.1 - 2.7e-23 83.0 0.1 3.3e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DnaJ PF00226.31 EGB09874.1 - 8.9e-16 57.8 1.4 1.3e-15 57.2 0.3 1.9 2 0 0 2 2 1 1 DnaJ domain zf-C3HC4 PF00097.25 EGB09874.1 - 2.4e-07 30.5 4.5 6.1e-07 29.2 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 EGB09874.1 - 4.4e-07 29.5 12.4 0.014 15.2 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 EGB09874.1 - 5.6e-07 29.5 2.4 8.9e-07 28.8 0.9 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGB09874.1 - 2.3e-06 27.4 3.9 6.3e-06 26.0 3.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB09874.1 - 2.7e-06 27.6 5.1 9.1e-06 25.9 5.1 2.0 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.6 EGB09874.1 - 9.4e-06 25.2 2.3 0.024 14.3 0.1 3.8 4 0 0 4 4 4 2 TPR repeat zf-RING_5 PF14634.6 EGB09874.1 - 1.2e-05 25.2 7.0 6.2e-05 22.9 7.0 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGB09874.1 - 1.9e-05 24.4 5.3 5.2e-05 23.0 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGB09874.1 - 2e-05 24.6 6.4 4.4e-05 23.5 6.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGB09874.1 - 7.6e-05 22.5 4.7 0.00025 20.8 4.7 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TPR_2 PF07719.17 EGB09874.1 - 0.00012 21.9 23.2 4.2 7.7 0.3 9.2 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB09874.1 - 0.0015 18.8 1.9 85 3.9 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB09874.1 - 0.0059 16.8 6.2 1.5 9.1 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGB09874.1 - 0.013 16.1 2.2 0.013 16.1 2.2 9.6 6 3 5 11 11 10 0 Tetratricopeptide repeat Sina PF03145.16 EGB09874.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Seven in absentia protein family zf-ANAPC11 PF12861.7 EGB09874.1 - 0.28 11.2 7.6 0.03 14.4 2.4 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_14 PF13428.6 EGB09874.1 - 0.89 10.5 0.1 0.89 10.5 0.1 8.6 6 3 2 8 8 7 0 Tetratricopeptide repeat DUF1644 PF07800.12 EGB09874.1 - 1.2 9.1 7.0 1.8 8.6 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) zf-rbx1 PF12678.7 EGB09874.1 - 2 8.8 10.2 0.048 13.9 3.0 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGB09874.1 - 6.6 6.6 10.6 14 5.5 7.6 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain C2 PF00168.30 EGB09875.1 - 3.6e-07 30.4 0.0 5.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain NT-C2 PF10358.9 EGB09875.1 - 0.0045 16.7 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ferlin_C PF16165.5 EGB09875.1 - 0.036 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus SHOCT PF09851.9 EGB09876.1 - 0.00014 21.5 1.0 0.00036 20.2 1.0 1.7 1 0 0 1 1 1 1 Short C-terminal domain FA_desaturase PF00487.24 EGB09877.1 - 2.4e-07 30.9 11.6 7.2e-07 29.3 11.6 1.8 1 1 0 1 1 1 1 Fatty acid desaturase HA2 PF04408.23 EGB09879.1 - 2e-12 47.3 2.5 2.5e-12 47.0 0.1 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGB09879.1 - 4.8e-12 46.2 0.0 8.4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGB09879.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGB09879.1 - 0.014 15.7 0.2 0.056 13.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB09879.1 - 0.028 13.8 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family EcoEI_R_C PF08463.10 EGB09879.1 - 0.23 11.6 0.9 0.51 10.4 0.2 1.9 2 0 0 2 2 2 0 EcoEI R protein C-terminal Gal-3-0_sulfotr PF06990.11 EGB09879.1 - 1.5 7.6 3.5 3 6.6 3.5 1.4 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase FKBP_C PF00254.28 EGB09880.1 - 4.7e-29 100.6 0.0 5.3e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Lycopene_cycl PF05834.12 EGB09881.1 - 4.1e-85 286.1 0.0 5.2e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EGB09881.1 - 3.8e-05 23.0 0.0 0.00011 21.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EGB09881.1 - 0.00029 20.1 0.2 0.00049 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGB09881.1 - 0.0045 16.4 0.2 0.0089 15.4 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGB09881.1 - 0.0061 15.3 0.0 0.0085 14.8 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EGB09881.1 - 0.0088 16.3 0.0 0.031 14.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB09881.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGB09881.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB09881.1 - 0.038 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 EGB09881.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGB09881.1 - 0.18 11.8 0.0 1.7 8.6 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mpv17_PMP22 PF04117.12 EGB09882.1 - 1.5e-14 54.0 1.7 1.5e-14 54.0 1.7 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family EGF_2 PF07974.13 EGB09884.1 - 1.2e-15 57.5 55.8 3.3e-06 27.4 6.2 5.2 4 1 0 4 4 4 4 EGF-like domain Laminin_EGF PF00053.24 EGB09884.1 - 0.039 14.1 4.7 0.039 14.1 4.7 4.6 2 1 2 4 4 4 0 Laminin EGF domain EGF PF00008.27 EGB09884.1 - 0.08 13.3 2.3 0.08 13.3 2.3 6.0 6 1 1 7 7 7 0 EGF-like domain Herpes_UL92 PF03048.14 EGB09884.1 - 1.5 8.6 6.3 2.3 7.9 6.3 1.3 1 0 0 1 1 1 0 UL92 family EGF_Tenascin PF18720.1 EGB09884.1 - 3.6 7.7 57.9 0.43 10.7 0.5 5.6 5 1 0 5 5 5 0 Tenascin EGF domain Ribosomal_L20 PF00453.18 EGB09885.1 - 7.8e-40 135.3 3.6 8.6e-40 135.2 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 CpcD PF01383.21 EGB09885.1 - 0.052 13.8 0.7 1.5 9.2 0.7 2.2 1 1 0 1 1 1 0 CpcD/allophycocyanin linker domain Ank_2 PF12796.7 EGB09886.1 - 1.7e-16 60.5 16.9 0.007 16.9 0.3 7.7 7 0 0 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB09886.1 - 2.3e-11 44.0 10.8 0.006 17.1 0.6 8.2 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB09886.1 - 4.1e-09 36.5 22.8 0.00039 20.7 1.5 8.5 8 0 0 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB09886.1 - 1.3e-07 31.3 20.3 2.2 9.1 0.2 10.6 13 0 0 13 13 13 3 Ankyrin repeat Velvet PF11754.8 EGB09886.1 - 0.069 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Velvet factor ABC_tran PF00005.27 EGB09888.1 - 5.4e-21 75.5 0.0 6.9e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB09888.1 - 2.2e-10 40.9 0.0 2.5e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB09888.1 - 0.00027 20.5 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB09888.1 - 0.0004 20.1 1.6 0.00086 19.1 1.2 1.7 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 EGB09888.1 - 0.00057 20.4 0.0 0.00084 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB09888.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB09888.1 - 0.0084 16.5 1.4 0.023 15.1 1.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 EGB09888.1 - 0.015 14.9 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 EGB09888.1 - 0.041 14.1 0.2 0.81 10.0 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 EGB09888.1 - 0.059 12.7 0.1 0.94 8.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGB09888.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGB09889.1 - 2.3e-21 76.8 0.0 4.4e-21 75.8 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB09889.1 - 8e-14 52.1 0.0 4e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EGB09889.1 - 0.00044 20.0 0.0 0.8 9.4 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_29 PF13555.6 EGB09889.1 - 0.0014 18.3 0.1 0.024 14.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGB09889.1 - 0.0019 17.6 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Ploopntkinase1 PF18748.1 EGB09889.1 - 0.0061 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase1 SbcCD_C PF13558.6 EGB09889.1 - 0.076 13.3 0.0 0.7 10.2 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Chloroa_b-bind PF00504.21 EGB09890.1 - 4.9e-26 92.2 0.1 6.7e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein UPF0176_N PF17773.1 EGB09891.1 - 9.1e-17 61.2 0.0 2e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 EGB09891.1 - 3.8e-08 33.6 5.6 3.8e-08 33.6 5.6 1.9 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 EGB09891.1 - 1.7e-07 31.7 0.0 1.6e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain FYVE PF01363.21 EGB09891.1 - 5.6 7.2 20.1 8 6.7 7.1 2.5 2 0 0 2 2 2 0 FYVE zinc finger APH PF01636.23 EGB09892.1 - 4.1e-07 30.2 8.0 4.1e-07 30.2 8.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGB09892.1 - 0.0086 15.4 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EGB09892.1 - 0.059 12.9 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_S28 PF05577.12 EGB09893.1 - 3.6e-90 302.8 0.0 5.4e-89 299.0 0.0 2.2 1 1 0 1 1 1 1 Serine carboxypeptidase S28 EF-hand_1 PF00036.32 EGB09894.1 - 6.2e-32 106.8 11.5 1.1e-09 37.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB09894.1 - 1.2e-27 96.1 7.6 8.3e-15 55.0 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB09894.1 - 3.2e-26 89.0 8.3 5.4e-10 38.4 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB09894.1 - 2.2e-19 69.0 7.6 6.9e-09 35.4 0.5 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB09894.1 - 2.8e-19 67.7 10.6 1.7e-06 27.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGB09894.1 - 2.9e-08 33.9 0.4 0.0028 17.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGB09894.1 - 1.2e-05 25.2 3.1 0.8 9.7 0.1 3.2 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB09894.1 - 2.8e-05 24.4 0.4 0.23 11.8 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EGB09894.1 - 0.00058 20.2 0.6 0.2 12.0 0.1 2.3 2 1 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 EGB09894.1 - 0.0027 17.7 2.6 1.8 8.5 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein SurA_N_2 PF13623.6 EGB09894.1 - 0.025 14.4 1.3 1.4 8.8 0.2 2.4 1 1 1 2 2 2 0 SurA N-terminal domain FGAR-AT_linker PF18072.1 EGB09894.1 - 0.026 15.1 0.1 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF3008 PF11450.8 EGB09894.1 - 0.041 14.0 0.2 0.041 14.0 0.2 2.2 3 0 0 3 3 2 0 Protein of unknwon function (DUF3008) IF2_N PF04760.15 EGB09894.1 - 0.06 13.2 2.3 19 5.2 0.0 3.7 3 1 1 4 4 4 0 Translation initiation factor IF-2, N-terminal region LETM1 PF07766.13 EGB09894.1 - 0.093 12.1 0.5 0.33 10.2 0.6 1.7 1 1 1 2 2 2 0 LETM1-like protein Acetyltransf_11 PF13720.6 EGB09894.1 - 0.11 13.0 0.1 0.97 9.9 0.0 2.3 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Toprim_2 PF13155.6 EGB09894.1 - 0.11 12.9 1.8 0.49 10.9 0.5 2.2 1 1 0 2 2 2 0 Toprim-like PMBR PF09373.10 EGB09894.1 - 0.13 12.4 0.0 12 6.2 0.0 3.6 4 1 1 5 5 5 0 Pseudomurein-binding repeat FKBP_N PF01346.18 EGB09894.1 - 0.21 12.5 1.3 0.75 10.8 0.4 2.1 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4194 PF13835.6 EGB09894.1 - 0.32 10.7 1.6 34 4.1 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4194) FKBP_C PF00254.28 EGB09897.1 - 1.1e-21 77.0 0.0 1.4e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase eIF-1a PF01176.19 EGB09897.1 - 0.00047 19.9 0.1 0.00081 19.1 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TauD PF02668.16 EGB09898.1 - 3.9e-22 79.3 0.0 7.2e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_1 PF00036.32 EGB09898.1 - 1.7e-16 58.5 0.4 6.2e-05 22.3 0.5 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB09898.1 - 3.7e-14 51.4 0.4 0.042 13.8 0.3 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGB09898.1 - 8e-14 51.8 2.9 2.7e-06 27.8 1.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair PH PF00169.29 EGB09898.1 - 1e-11 45.2 0.0 1.8e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 PH domain EF-hand_5 PF13202.6 EGB09898.1 - 9.4e-07 28.1 1.3 0.23 11.0 0.0 4.5 4 0 0 4 4 4 1 EF hand ubiquitin PF00240.23 EGB09898.1 - 2.2e-06 27.3 0.0 5.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family zf-RING_2 PF13639.6 EGB09898.1 - 2e-05 24.8 4.3 3.9e-05 23.9 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain EF-hand_8 PF13833.6 EGB09898.1 - 2.4e-05 24.1 2.9 0.11 12.3 1.3 3.5 3 1 1 4 4 4 2 EF-hand domain pair WWE PF02825.20 EGB09898.1 - 0.0007 20.1 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 WWE domain zf-RING_5 PF14634.6 EGB09898.1 - 0.014 15.3 2.3 0.027 14.4 2.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB09898.1 - 0.019 15.0 4.5 0.045 13.8 4.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGB09898.1 - 0.027 14.3 2.5 0.046 13.6 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB09898.1 - 0.14 12.5 1.8 0.3 11.4 1.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain YukD PF08817.10 EGB09898.1 - 0.15 12.8 1.1 0.7 10.6 0.2 2.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD EF-hand_4 PF12763.7 EGB09898.1 - 0.21 11.5 0.4 0.52 10.3 0.4 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Prok-RING_4 PF14447.6 EGB09898.1 - 0.3 11.0 6.6 0.44 10.5 0.7 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGB09898.1 - 0.35 10.8 1.9 0.7 9.8 1.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB09898.1 - 2.1 8.2 4.9 8.2 6.4 4.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribonuc_red_lgC PF02867.15 EGB09899.1 - 1e-177 591.9 0.0 1.5e-177 591.3 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGB09899.1 - 4.2e-23 81.1 0.1 1.2e-22 79.7 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGB09899.1 - 6.1e-18 65.2 0.1 1.5e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 ATP cone domain SmpB PF01668.18 EGB09900.1 - 2.9e-54 182.9 0.5 3.2e-54 182.7 0.5 1.0 1 0 0 1 1 1 1 SmpB protein Arylsulfotrans PF05935.11 EGB09901.1 - 2.4e-05 23.4 1.4 4.9e-05 22.4 1.4 1.5 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Chloroa_b-bind PF00504.21 EGB09902.1 - 6.2e-27 95.1 0.1 1.2e-26 94.1 0.1 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ATG22 PF11700.8 EGB09903.1 - 2.8e-24 85.6 8.2 1.8e-22 79.7 8.2 2.1 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGB09903.1 - 6.5e-12 45.0 29.7 1.1e-11 44.3 29.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGB09903.1 - 1.7e-05 23.6 4.4 3.1e-05 22.7 4.4 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 EGB09903.1 - 0.00026 20.0 1.3 0.00044 19.2 1.3 1.3 1 0 0 1 1 1 1 MFS_1 like family TIM PF00121.18 EGB09904.1 - 2.1e-74 250.0 0.0 2.9e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase DUF4075 PF13294.6 EGB09904.1 - 0.092 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) Robl_LC7 PF03259.17 EGB09905.1 - 7.9e-27 92.9 0.1 8.6e-27 92.7 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGB09905.1 - 4e-06 26.7 0.0 5.1e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 EGB09905.1 - 0.0036 17.6 0.1 0.0044 17.4 0.1 1.1 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain DUF5076 PF16826.5 EGB09905.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5076) cwf21 PF08312.12 EGB09908.1 - 0.32 11.2 4.8 8.8 6.6 1.1 3.2 2 1 0 2 2 2 0 cwf21 domain Peptidase_S10 PF00450.22 EGB09909.1 - 6.8e-121 404.6 0.1 8.4e-121 404.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EGB09909.1 - 0.024 15.3 5.0 0.12 12.9 5.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family GTP_EFTU PF00009.27 EGB09910.1 - 4.6e-54 182.9 0.0 7.1e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGB09910.1 - 7e-42 142.3 0.0 1.6e-41 141.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGB09910.1 - 5.2e-15 55.6 0.1 1.3e-14 54.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGB09910.1 - 1.8e-05 24.8 0.0 0.00056 20.0 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB09910.1 - 0.0068 15.8 0.3 0.024 14.0 0.1 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGB09910.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU_D4 PF14578.6 EGB09910.1 - 0.011 15.7 0.1 0.04 13.8 0.1 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FlpD PF02662.16 EGB09910.1 - 0.018 15.1 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU PF00009.27 EGB09911.1 - 4.6e-54 182.9 0.0 7.1e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGB09911.1 - 7e-42 142.3 0.0 1.6e-41 141.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGB09911.1 - 5.2e-15 55.6 0.1 1.3e-14 54.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGB09911.1 - 1.8e-05 24.8 0.0 0.00056 20.0 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB09911.1 - 0.0068 15.8 0.3 0.024 14.0 0.1 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGB09911.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU_D4 PF14578.6 EGB09911.1 - 0.011 15.7 0.1 0.04 13.8 0.1 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FlpD PF02662.16 EGB09911.1 - 0.018 15.1 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit MFS_1 PF07690.16 EGB09912.1 - 1.5e-19 70.2 47.6 2.1e-18 66.4 29.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB09912.1 - 1.9e-13 50.1 9.1 8.8e-13 47.9 9.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Amidohydro_2 PF04909.14 EGB09913.1 - 4.6e-19 69.3 10.0 8.4e-19 68.4 10.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Pkinase_Tyr PF07714.17 EGB09914.1 - 7.9e-31 107.3 0.0 9e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB09914.1 - 1.1e-28 100.3 0.0 1.2e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGB09914.1 - 0.0086 16.0 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mito_carr PF00153.27 EGB09915.1 - 2.7e-41 139.4 5.8 3.8e-16 58.8 0.0 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein Tcf25 PF04910.14 EGB09915.1 - 4.9e-25 88.4 0.0 7.8e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_2 PF07719.17 EGB09915.1 - 3.5e-06 26.7 0.1 0.13 12.4 0.0 3.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Sensor PF13796.6 EGB09915.1 - 0.001 19.2 3.4 0.011 15.8 0.5 3.3 2 0 0 2 2 2 1 Putative sensor DNA_pol_A_exo1 PF01612.20 EGB09915.1 - 0.0026 17.5 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease LYRIC PF15686.5 EGB09915.1 - 0.14 11.7 16.1 0.068 12.7 5.5 2.2 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family RXT2_N PF08595.11 EGB09915.1 - 4.5 7.3 14.7 1.8 8.5 3.9 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal K_channel_TID PF07941.11 EGB09916.1 - 0.79 10.2 11.6 2.4 8.7 11.6 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_L4 PF00573.22 EGB09917.1 - 2e-58 197.3 0.6 2.3e-58 197.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family IR1-M PF12185.8 EGB09917.1 - 0.17 11.9 0.0 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Aldo_ket_red PF00248.21 EGB09918.1 - 4.1e-29 101.7 0.0 4e-20 72.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family HTH_AsnC-type PF13404.6 EGB09918.1 - 0.1 12.4 0.4 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HNH_repeat PF18780.1 EGB09918.1 - 0.17 11.7 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Homing endonuclease repeat DENN PF02141.21 EGB09919.1 - 1.8e-18 67.2 0.0 9.9e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain WD40 PF00400.32 EGB09919.1 - 2.9e-07 31.1 10.4 0.018 15.9 0.1 7.4 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09919.1 - 1.5e-05 25.2 0.3 29 5.0 0.0 7.1 3 2 4 7 7 7 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGB09919.1 - 2.7e-05 23.7 0.0 0.01 15.2 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Ion_trans PF00520.31 EGB09919.1 - 7.8e-05 22.0 18.6 0.35 10.0 0.0 3.1 2 1 0 2 2 2 2 Ion transport protein uDENN PF03456.18 EGB09919.1 - 0.00069 20.3 0.0 0.0017 19.1 0.0 1.7 1 0 0 1 1 1 1 uDENN domain Ank_2 PF12796.7 EGB09919.1 - 0.03 14.9 0.2 0.17 12.5 0.2 2.0 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Kelch_1 PF01344.25 EGB09919.1 - 0.084 12.5 0.5 23 4.7 0.0 3.2 2 0 0 2 2 2 0 Kelch motif Ank_4 PF13637.6 EGB09920.1 - 2.7e-18 66.1 5.2 1.3e-12 47.9 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB09920.1 - 1.7e-13 50.3 2.9 1.4e-07 31.6 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGB09920.1 - 1.3e-12 48.1 0.2 5e-12 46.3 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB09920.1 - 5.8e-12 45.6 3.0 5.4e-09 36.1 0.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB09920.1 - 7.1e-12 44.4 0.2 3.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Shigella_OspC PF06128.11 EGB09920.1 - 0.069 12.9 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Shigella flexneri OspC protein Rhamno_transf PF11316.8 EGB09921.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Putative rhamnosyl transferase PQQ PF01011.21 EGB09922.1 - 0.00011 21.9 1.2 0.23 11.5 0.0 3.1 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 EGB09922.1 - 0.00013 21.7 0.6 0.0022 17.6 0.2 2.1 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 EGB09922.1 - 0.0014 19.0 0.9 0.0014 19.0 0.9 3.1 3 1 0 3 3 3 1 PQQ-like domain WD40 PF00400.32 EGB09922.1 - 0.0027 18.5 0.0 0.033 15.1 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat TPT PF03151.16 EGB09924.1 - 1.5e-08 34.3 10.4 2e-08 34.0 10.4 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family MIP PF00230.20 EGB09925.1 - 9.6e-37 126.9 10.4 1.3e-36 126.5 10.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_S17e PF00833.18 EGB09926.1 - 1.8e-62 208.7 0.1 2e-62 208.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 CRAL_TRIO PF00650.20 EGB09927.1 - 6.2e-12 45.5 0.0 7.7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGB09927.1 - 0.00037 20.6 0.0 0.00048 20.3 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Sel1 PF08238.12 EGB09928.1 - 7.7e-15 55.0 11.6 7.2e-06 26.5 1.1 3.1 3 0 0 3 3 3 3 Sel1 repeat Myb_DNA-binding PF00249.31 EGB09929.1 - 5.1e-29 100.2 5.3 2.9e-14 53.0 0.2 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB09929.1 - 3.9e-21 75.0 1.3 1.4e-15 57.2 0.1 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB09929.1 - 1.2e-05 25.1 0.0 8.7e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EGB09929.1 - 0.0015 18.6 0.0 0.0088 16.1 0.0 1.9 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 EGB09929.1 - 0.0026 18.1 2.2 0.014 15.7 0.3 2.3 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGB09929.1 - 0.061 13.6 0.7 6.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Amidohydro_2 PF04909.14 EGB09930.1 - 5.8e-23 82.1 1.2 1.1e-22 81.2 1.2 1.4 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 EGB09930.1 - 1.7e-15 56.8 50.0 8.9e-15 54.5 35.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB09930.1 - 8.7e-05 21.6 0.1 0.00017 20.6 0.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TMEM208_SND2 PF05620.11 EGB09931.1 - 3.5e-22 79.0 1.5 8.8e-15 54.9 0.0 2.0 1 1 1 2 2 2 2 SRP-independent targeting protein 2/TMEM208 Ribosomal_60s PF00428.19 EGB09931.1 - 7.6 7.2 11.7 0.26 11.9 0.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lactamase_B_2 PF12706.7 EGB09932.1 - 3.7e-19 69.1 0.2 9.3e-19 67.7 0.2 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EGB09932.1 - 3.1e-07 30.0 0.0 5.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease 2OG-FeII_Oxy_3 PF13640.6 EGB09933.1 - 1.2e-16 61.4 0.0 1.7e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB09933.1 - 0.0005 20.5 0.0 0.00077 19.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 EGB09934.1 - 3.4e-16 58.8 1.3 9e-06 25.4 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB09934.1 - 4.8e-05 23.4 0.0 0.019 15.1 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 EGB09934.1 - 0.0024 17.7 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 EGB09934.1 - 0.031 14.5 1.5 1.6 8.9 0.0 3.6 4 1 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter AIM24 PF01987.17 EGB09935.1 - 5.5e-42 143.8 0.0 6.3e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Prot_ATP_ID_OB PF16450.5 EGB09935.1 - 0.037 14.0 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain zf-NOSIP PF15906.5 EGB09935.1 - 0.41 10.8 0.1 0.41 10.8 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein AIM24 PF01987.17 EGB09936.1 - 1.4e-37 129.5 0.0 1.6e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Prot_ATP_ID_OB PF16450.5 EGB09936.1 - 0.025 14.5 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain PhoD PF09423.10 EGB09937.1 - 1.4e-17 63.8 0.0 3.7e-16 59.1 0.0 2.4 1 1 0 1 1 1 1 PhoD-like phosphatase MS_channel PF00924.18 EGB09938.1 - 9.5e-27 93.9 0.0 1.5e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel UBM PF14377.6 EGB09938.1 - 0.13 11.8 0.5 0.43 10.1 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin binding region WD40 PF00400.32 EGB09939.1 - 1.7e-13 50.8 13.3 0.00053 20.7 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB09939.1 - 7.3e-09 35.8 0.2 0.044 14.1 0.0 4.8 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Phytase-like PF13449.6 EGB09939.1 - 0.035 14.1 0.0 0.074 13.0 0.0 1.6 2 0 0 2 2 2 0 Esterase-like activity of phytase ASH PF15780.5 EGB09940.1 - 1.5e-21 76.4 1.8 0.015 15.5 0.0 8.9 8 0 0 8 8 8 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGB09940.1 - 4.1e-09 36.5 2.1 0.43 10.8 0.0 6.7 6 1 2 8 8 8 4 Flagellar-associated PapD-like Motile_Sperm PF00635.26 EGB09940.1 - 4.6e-05 23.2 0.6 5.4 6.9 0.0 5.1 5 0 0 5 5 5 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 EGB09940.1 - 0.14 12.4 1.3 25 5.2 0.1 4.1 4 0 0 4 4 4 0 Transmembrane protein 131-like Complex1_LYR_2 PF13233.6 EGB09941.1 - 1.1e-11 45.3 0.1 1.4e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGB09941.1 - 7.5e-05 22.7 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EF-hand_1 PF00036.32 EGB09942.1 - 1.6e-10 39.7 0.5 0.00024 20.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB09942.1 - 2.4e-09 36.3 0.3 0.0013 18.5 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGB09942.1 - 1.1e-08 35.4 0.2 0.0008 19.8 0.3 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB09942.1 - 8.5e-06 25.5 1.3 0.00046 20.0 0.6 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 EGB09942.1 - 0.014 15.4 0.1 4.6 7.2 0.0 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EGB09942.1 - 0.019 14.5 0.1 0.42 10.2 0.0 2.8 3 0 0 3 3 3 0 EF hand Kinesin PF00225.23 EGB09943.1 - 8.1e-83 278.1 0.0 1.4e-82 277.3 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB09943.1 - 3.3e-16 59.6 0.0 3.8e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 Microtubule binding 6PF2K PF01591.18 EGB09944.1 - 1.9e-56 190.9 0.0 2.4e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGB09944.1 - 1.1e-26 93.8 0.0 2.4e-26 92.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGB09944.1 - 0.00013 22.2 0.0 0.00025 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB09944.1 - 0.027 15.0 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PAP2 PF01569.21 EGB09946.1 - 1.9e-19 69.8 0.5 5.6e-19 68.3 0.5 1.9 1 0 0 1 1 1 1 PAP2 superfamily AAA_assoc_2 PF16193.5 EGB09946.1 - 0.012 15.9 0.9 4.3 7.7 0.0 4.1 3 0 0 3 3 3 0 AAA C-terminal domain PAP2_3 PF14378.6 EGB09946.1 - 0.38 10.4 8.5 10 5.8 7.1 2.9 1 1 0 1 1 1 0 PAP2 superfamily Sulfotransfer_3 PF13469.6 EGB09947.1 - 0.00068 20.1 0.0 0.025 15.0 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB09947.1 - 0.072 12.6 0.0 0.88 9.0 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase domain U-box PF04564.15 EGB09948.1 - 3.1e-21 75.3 0.0 5.2e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 U-box domain SAM_1 PF00536.30 EGB09948.1 - 6.2e-15 55.4 0.0 5.5e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGB09948.1 - 2.4e-12 46.7 0.0 1.7e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Ank_2 PF12796.7 EGB09948.1 - 9.3e-09 35.8 0.5 1.9e-06 28.4 0.1 2.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB09948.1 - 1.1e-08 34.6 1.4 0.099 13.3 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EGB09948.1 - 5.7e-07 29.7 3.2 0.00018 21.8 0.2 4.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB09948.1 - 1.9e-06 28.3 0.6 0.00085 19.9 0.1 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) zf-NOSIP PF15906.5 EGB09948.1 - 2.4e-05 24.4 1.1 0.094 12.9 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of nitric oxide synthase-interacting protein Ank PF00023.30 EGB09948.1 - 0.00054 20.3 3.2 0.24 11.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DNA_methylase PF00145.17 EGB09949.1 - 2.3e-47 162.0 0.0 4.9e-46 157.6 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Cyt-b5 PF00173.28 EGB09949.1 - 1.8e-08 34.4 0.0 4.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 3HCDH_N PF02737.18 EGB09950.1 - 2.9e-54 183.7 0.1 6.2e-54 182.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EGB09950.1 - 2.5e-37 128.5 1.3 3.8e-37 128.0 1.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 EGB09950.1 - 5.8e-29 100.6 0.9 2.7e-18 66.3 0.1 3.3 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 EGB09950.1 - 2.2e-17 63.6 0.8 5.3e-17 62.3 0.8 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 EGB09950.1 - 0.0072 16.5 0.2 0.035 14.3 0.2 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGB09950.1 - 2.1 9.0 4.7 2.4 8.8 0.6 2.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SNF2_N PF00176.23 EGB09951.1 - 2.6e-58 197.4 0.0 3.6e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB09951.1 - 2.9e-16 59.8 0.0 4.6e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB09951.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L18p PF00861.22 EGB09952.1 - 2e-32 112.0 0.3 2.6e-32 111.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Peptidase_S49 PF01343.18 EGB09953.1 - 4.5e-39 133.9 0.0 6.2e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 EGB09953.1 - 2.3e-24 86.2 0.7 6.4e-23 81.5 0.5 2.0 2 0 0 2 2 2 1 Peptidase family S49 N-terminal SDH_sah PF01972.16 EGB09953.1 - 0.0012 17.9 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 EGB09953.1 - 0.0037 17.2 0.8 0.0059 16.5 0.8 1.5 1 1 0 1 1 1 1 Clp protease Methyltransf_11 PF08241.12 EGB09954.1 - 2e-13 50.8 0.2 8e-13 48.9 0.2 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB09954.1 - 6.8e-13 49.2 0.0 2.3e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB09954.1 - 3.8e-11 43.5 0.2 3.8e-11 43.5 0.2 2.9 3 1 1 4 4 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB09954.1 - 1.7e-08 34.4 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB09954.1 - 4.7e-06 26.3 0.1 2.7e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGB09954.1 - 3e-05 23.9 0.0 6.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB09954.1 - 6.9e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPR_17 PF13431.6 EGB09954.1 - 0.00016 21.8 0.8 0.41 11.1 0.5 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09954.1 - 0.00029 21.3 42.6 0.008 16.7 5.9 4.9 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09954.1 - 0.0051 17.4 11.6 0.0051 17.4 11.6 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB09954.1 - 0.01 16.0 4.5 0.01 16.0 4.5 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB09954.1 - 0.013 15.2 0.2 0.013 15.2 0.2 3.7 4 1 1 5 5 4 0 TPR repeat Fis1_TPR_C PF14853.6 EGB09954.1 - 0.43 10.7 0.1 0.43 10.7 0.1 2.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EGB09954.1 - 0.54 11.2 68.0 0.35 11.8 6.3 8.9 4 2 5 9 9 9 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 EGB09955.1 - 1.3e-11 44.4 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EF-hand_6 PF13405.6 EGB09956.1 - 0.00033 20.4 0.1 0.042 13.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGB09956.1 - 0.00033 20.0 0.1 0.2 11.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB09956.1 - 0.0011 19.4 0.2 0.003 18.0 0.1 1.8 1 1 0 1 1 1 1 EF-hand domain pair Histone_HNS PF00816.21 EGB09956.1 - 0.16 12.8 1.5 0.56 11.1 0.4 2.6 2 1 0 2 2 2 0 H-NS histone family DUF393 PF04134.12 EGB09957.1 - 1.9e-24 87.2 0.0 2.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Methyltransf_23 PF13489.6 EGB09958.1 - 4.2e-05 23.4 0.0 8.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB09958.1 - 0.0041 17.8 0.0 0.012 16.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB09958.1 - 0.027 15.2 0.0 0.081 13.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain ArfGap PF01412.18 EGB09959.1 - 6.7e-32 110.0 0.0 1.3e-31 109.1 0.0 1.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf MFS_1 PF07690.16 EGB09960.1 - 3.2e-05 23.0 60.1 0.0024 16.9 31.0 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily tRNA-synt_2b PF00587.25 EGB09961.1 - 4.5e-36 124.5 0.2 3.6e-35 121.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGB09961.1 - 8.8e-20 70.9 3.4 8.8e-20 70.9 3.4 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF4208 PF13907.6 EGB09961.1 - 0.047 14.1 0.0 8.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) APG6_N PF17675.1 EGB09961.1 - 6.7 7.2 11.6 0.81 10.2 6.2 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region Pkinase_Tyr PF07714.17 EGB09962.1 - 1.1e-50 172.3 0.0 1.2e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB09962.1 - 5.7e-35 120.9 0.0 7.1e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGB09962.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB09962.1 - 0.0087 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB09962.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGB09962.1 - 0.033 14.1 0.0 0.23 11.4 0.1 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family LRR_6 PF13516.6 EGB09963.1 - 7.8e-16 56.7 0.7 0.034 14.2 0.0 7.7 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EGB09963.1 - 7.2e-07 29.4 0.0 1.9 9.0 0.0 4.6 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB09963.1 - 0.00012 22.2 0.3 9.3 7.3 0.0 5.7 5 3 0 5 5 5 1 Leucine Rich Repeat Glyco_hydro_99 PF16317.5 EGB09964.1 - 4e-94 315.6 0.1 4.9e-94 315.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 EGB09964.1 - 0.035 13.6 0.0 1.1 8.7 0.0 2.1 1 1 0 2 2 2 0 Glycosyltransferase WbsX PTR2 PF00854.21 EGB09966.1 - 7.1e-72 242.4 14.6 3.7e-37 128.1 1.4 2.0 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 EGB09966.1 - 4.4e-12 45.6 30.9 8.7e-07 28.2 12.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_28 PF00295.17 EGB09967.1 - 5.4e-58 196.6 0.0 6.8e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EGB09967.1 - 6.8e-06 26.1 0.0 2.7e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 EGB09967.1 - 0.22 11.4 0.0 0.52 10.1 0.0 1.5 1 1 0 1 1 1 0 Right handed beta helix region TPR_9 PF13371.6 EGB09967.1 - 0.23 11.6 8.2 1.2 9.4 6.6 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat UCH PF00443.29 EGB09968.1 - 7e-38 130.6 0.0 1.4e-37 129.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB09968.1 - 8.5e-12 45.3 0.0 4.4e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase 2OG-FeII_Oxy_3 PF13640.6 EGB09968.1 - 2.2e-09 38.1 0.0 5.6e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MOFRL PF05161.13 EGB09968.1 - 0.076 13.2 0.5 8.1 6.7 0.0 2.7 2 0 0 2 2 2 0 MOFRL family Aldolase_II PF00596.21 EGB09969.1 - 5.7e-29 101.4 0.3 6.6e-29 101.2 0.3 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldo_ket_red PF00248.21 EGB09970.1 - 4.9e-33 114.6 0.0 3.2e-31 108.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0029 PF01205.19 EGB09971.1 - 1.7e-09 37.9 0.0 3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 LPP PF04728.13 EGB09971.1 - 1.6 9.2 3.7 2.5 8.6 2.2 2.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF1242 PF06842.12 EGB09972.1 - 1.2e-20 73.0 0.3 2e-20 72.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) PsaX PF08078.12 EGB09972.1 - 1.4 8.9 5.1 5.5 7.0 1.5 2.2 2 0 0 2 2 2 0 PsaX family Exo_endo_phos PF03372.23 EGB09973.1 - 3.3e-14 53.0 1.6 6e-14 52.1 1.6 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3293 PF11697.8 EGB09973.1 - 0.16 12.5 0.1 31 5.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) GBP PF02263.19 EGB09974.1 - 5e-21 75.1 0.0 5.8e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EGB09974.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Dynamin family DUF2791 PF10923.8 EGB09974.1 - 0.11 11.4 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) MMR_HSR1 PF01926.23 EGB09974.1 - 0.13 12.4 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase GBP PF02263.19 EGB09975.1 - 1.9e-32 112.5 0.0 2.1e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EGB09975.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 EGB09975.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase FG-GAP_2 PF14312.6 EGB09976.1 - 9.4e-140 454.8 96.4 1.8e-23 82.5 6.7 7.5 7 0 0 7 7 7 7 FG-GAP repeat Kelch_6 PF13964.6 EGB09976.1 - 9.7e-12 44.7 22.3 0.17 12.2 0.2 7.3 7 0 0 7 7 7 5 Kelch motif PQQ_3 PF13570.6 EGB09976.1 - 1.3e-08 35.1 49.1 0.42 11.2 0.9 7.8 7 0 0 7 7 7 6 PQQ-like domain BNR_2 PF13088.6 EGB09976.1 - 2.1e-08 33.8 0.7 0.048 13.0 0.0 3.6 1 1 2 3 3 3 3 BNR repeat-like domain Sortilin-Vps10 PF15902.5 EGB09976.1 - 1.6e-06 27.2 4.4 0.014 14.2 0.2 3.3 1 1 2 4 4 4 3 Sortilin, neurotensin receptor 3, Phage_holin_2_4 PF16082.5 EGB09976.1 - 0.00013 21.6 42.1 0.91 9.3 0.2 8.0 7 1 1 8 8 8 5 Bacteriophage holin family, superfamily II-like CaATP_NAI PF12515.8 EGB09976.1 - 0.00086 18.9 0.2 37 4.0 0.0 4.5 4 0 0 4 4 4 0 Ca2+-ATPase N terminal autoinhibitory domain BNR PF02012.20 EGB09976.1 - 0.006 16.4 28.8 2.8 8.3 0.4 6.8 6 0 0 6 6 6 2 BNR/Asp-box repeat Herpes_gE PF02480.16 EGB09976.1 - 0.0069 15.2 4.3 0.95 8.1 0.1 3.2 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E PsaX PF08078.12 EGB09976.1 - 0.015 15.2 10.5 81 3.3 0.1 7.3 7 0 0 7 7 7 0 PsaX family Clathrin_lg_ch PF01086.17 EGB09976.1 - 0.036 14.1 0.8 1.7e+02 2.1 0.0 4.5 5 0 0 5 5 5 0 Clathrin light chain DUF4229 PF14012.6 EGB09976.1 - 0.036 14.2 2.5 0.09 12.9 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) ORF_2_N PF18492.1 EGB09976.1 - 0.044 14.0 9.3 27 5.0 0.0 6.0 5 2 2 7 7 7 0 Open reading frame 2 N-terminal domain EphA2_TM PF14575.6 EGB09976.1 - 0.051 14.5 0.1 0.091 13.7 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F5_F8_type_C PF00754.25 EGB09976.1 - 0.22 11.7 18.2 14 5.8 0.2 5.7 3 2 3 6 6 6 0 F5/8 type C domain Lectin_leg-like PF03388.13 EGB09976.1 - 0.27 10.5 7.1 6.1 6.1 0.1 4.6 1 1 4 6 6 6 0 Legume-like lectin family Transgly PF00912.22 EGB09976.1 - 0.56 9.6 4.1 25 4.3 0.1 4.1 4 0 0 4 4 4 0 Transglycosylase Pkinase_Tyr PF07714.17 EGB09977.1 - 4e-48 164.0 0.0 6.2e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB09977.1 - 1.5e-34 119.5 0.0 3e-34 118.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 EGB09977.1 - 0.00071 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB09977.1 - 0.0083 15.5 0.1 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB09977.1 - 0.018 13.9 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGB09977.1 - 0.072 13.0 0.0 0.26 11.2 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family 2OG-FeII_Oxy_3 PF13640.6 EGB09978.1 - 9.1e-07 29.7 0.0 1.6e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EGB09978.1 - 0.038 14.2 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.25 EGB09979.1 - 8.7e-15 54.7 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB09979.1 - 8e-10 38.7 1.5 1e-09 38.3 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L22e PF01776.17 EGB09980.1 - 2e-45 153.6 1.1 2.3e-45 153.5 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF588 PF04535.12 EGB09981.1 - 7.2e-07 29.1 9.5 7.2e-07 29.1 9.5 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF588) DUF3410 PF11890.8 EGB09981.1 - 0.014 15.2 0.6 0.031 14.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) MARVEL PF01284.23 EGB09981.1 - 0.52 10.3 12.7 0.77 9.8 10.2 2.5 2 1 0 2 2 2 0 Membrane-associating domain TctB PF07331.11 EGB09981.1 - 1.9 8.7 7.2 1.5 9.1 3.8 2.3 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DnaJ PF00226.31 EGB09982.1 - 1e-21 76.8 0.0 1.1e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain FA_desaturase PF00487.24 EGB09983.1 - 3.2e-27 96.0 19.9 3.2e-27 96.0 19.9 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGB09983.1 - 6.3e-13 48.7 0.0 1.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4118 PF13493.6 EGB09983.1 - 0.014 15.2 0.8 0.045 13.5 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Peptidase_S41 PF03572.18 EGB09984.1 - 8e-39 132.9 0.0 1.2e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EGB09984.1 - 0.0024 17.7 0.0 0.0088 15.9 0.0 2.0 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGB09984.1 - 0.033 14.5 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 EGB09984.1 - 0.086 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF3485 PF11984.8 EGB09984.1 - 0.16 11.7 0.7 2.5 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3485) PDEase_I PF00233.19 EGB09985.1 - 1.3e-58 198.6 0.0 1.5e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EGB09985.1 - 0.007 16.6 0.2 0.012 15.8 0.2 1.6 1 1 0 1 1 1 1 HD domain Trypan_PARP PF05887.11 EGB09985.1 - 3.3 7.7 18.5 5.4 7.0 18.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PhyH PF05721.13 EGB09986.1 - 2.1e-15 57.6 0.1 3.7e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 EGB09987.1 - 2e-12 47.9 1.7 5.3e-12 46.4 1.7 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_transf_10 PF00852.19 EGB09987.1 - 2.5e-05 24.1 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term 2OG-FeII_Oxy_5 PF13759.6 EGB09987.1 - 0.022 15.1 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase FKBP_C PF00254.28 EGB09988.1 - 4.1e-23 81.5 0.0 7.5e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EGB09988.1 - 1.4e-10 40.4 7.7 3.6e-05 23.5 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGB09988.1 - 1.9e-08 34.3 2.0 1.9e-08 34.3 2.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB09988.1 - 2.9e-08 33.2 3.4 3.2e-06 26.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB09988.1 - 4.1e-06 27.3 11.1 1.2e-05 25.8 5.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB09988.1 - 5e-05 23.2 0.3 0.00047 20.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB09988.1 - 8.4e-05 22.2 1.5 0.12 12.1 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EGB09988.1 - 0.0009 19.9 10.1 0.0097 16.7 0.6 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB09988.1 - 0.0012 19.3 5.1 0.43 11.3 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat UvrD_C PF13361.6 EGB09988.1 - 0.009 15.4 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain TPR_17 PF13431.6 EGB09988.1 - 0.018 15.4 0.0 0.6 10.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB09988.1 - 0.048 14.2 1.9 0.048 14.2 1.9 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 EGB09989.1 - 1.1e-37 129.8 0.0 1.2e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sacchrp_dh_NADP PF03435.18 EGB09990.1 - 5e-13 49.4 0.3 7e-13 49.0 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGB09990.1 - 0.00025 21.0 1.0 0.00038 20.4 1.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGB09990.1 - 0.027 14.0 0.1 0.062 12.7 0.1 1.6 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB09990.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1168 PF06658.12 EGB09991.1 - 3.8e-25 88.3 4.8 3.8e-25 88.3 4.8 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1168) Polyketide_cyc PF03364.20 EGB09991.1 - 6.3e-05 23.2 0.3 0.00014 22.1 0.3 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ephrin_rec_like PF07699.13 EGB09992.1 - 1.4e-17 63.2 21.0 4.1e-07 29.7 0.7 3.1 2 1 1 3 3 3 3 Putative ephrin-receptor like VSP PF03302.13 EGB09992.1 - 0.16 10.8 22.4 18 4.0 0.6 2.2 1 1 0 1 1 1 0 Giardia variant-specific surface protein TNFR_c6 PF00020.18 EGB09992.1 - 0.2 12.1 11.1 7.3 7.1 1.8 4.4 1 1 3 4 4 4 0 TNFR/NGFR cysteine-rich region DUF2318 PF10080.9 EGB09992.1 - 5.4 7.2 12.1 1.5 8.9 3.4 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2318) CLP_protease PF00574.23 EGB09993.1 - 7e-50 169.4 0.0 8.7e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease Exostosin PF03016.15 EGB09994.1 - 5.3e-05 22.6 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Exostosin family ABC_membrane PF00664.23 EGB09995.1 - 8.6e-50 169.9 18.3 2.9e-25 89.5 4.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGB09995.1 - 1.1e-42 145.7 0.0 6.6e-25 88.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGB09995.1 - 1.6e-08 34.3 2.6 0.016 14.7 0.1 3.6 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGB09995.1 - 1.9e-05 24.7 1.2 0.22 11.6 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB09995.1 - 0.00021 21.7 4.2 0.89 9.9 2.6 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGB09995.1 - 0.00022 21.2 2.2 0.27 11.0 0.1 3.5 3 1 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB09995.1 - 0.00022 20.9 0.5 0.55 10.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EGB09995.1 - 0.0022 18.2 1.9 0.015 15.4 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EGB09995.1 - 0.004 17.7 0.1 1.5 9.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EGB09995.1 - 0.02 14.8 1.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 EGB09995.1 - 0.027 14.3 1.6 3.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EGB09995.1 - 0.028 14.2 1.1 1.4 8.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB09995.1 - 0.041 13.2 0.2 0.76 9.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Tcp10_C PF07202.13 EGB09995.1 - 0.1 12.5 0.8 0.19 11.7 0.8 1.3 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Dynamin_N PF00350.23 EGB09995.1 - 0.14 12.2 7.8 0.29 11.2 0.4 2.6 3 0 0 3 3 3 0 Dynamin family KAP_NTPase PF07693.14 EGB09995.1 - 0.22 10.7 0.3 1.1 8.4 0.0 2.2 3 0 0 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.22 EGB09995.1 - 0.27 10.4 3.4 9.6 5.3 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_22 PF13401.6 EGB09995.1 - 0.29 11.4 4.3 13 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Secretin PF00263.21 EGB09995.1 - 0.31 10.7 1.9 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial type II and III secretion system protein AAA PF00004.29 EGB09995.1 - 0.44 11.0 2.9 5.2 7.5 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Spore_YabQ PF09578.10 EGB09996.1 - 0.0009 19.4 1.8 1.4 9.2 0.1 2.5 2 0 0 2 2 2 2 Spore cortex protein YabQ (Spore_YabQ) DUF2776 PF10951.8 EGB09996.1 - 0.011 15.0 3.4 1 8.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2776) Ion_trans PF00520.31 EGB09998.1 - 1.1e-38 132.9 6.2 1.4e-38 132.5 6.2 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGB09998.1 - 1.9e-06 26.8 6.8 0.0049 15.6 1.2 2.3 2 0 0 2 2 2 2 Polycystin cation channel DUF3742 PF12553.8 EGB09998.1 - 0.056 13.6 0.1 0.53 10.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3742) Sigma_M_inh PF17453.2 EGB09998.1 - 2 8.9 6.7 0.24 11.8 1.3 2.2 2 1 0 2 2 2 0 Sigma-M inhibitor APH PF01636.23 EGB09999.1 - 1.2e-20 74.5 4.2 1.5e-20 74.2 4.2 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Dehydrin PF00257.19 EGB10000.1 - 0.41 11.2 1.5 1.3 9.6 1.5 1.8 1 0 0 1 1 1 0 Dehydrin Adaptin_N PF01602.20 EGB10001.1 - 2.3e-70 237.7 1.7 2.7e-70 237.4 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGB10001.1 - 2.9e-10 40.4 0.1 2.4e-09 37.5 0.0 2.2 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF3050 PF11251.8 EGB10001.1 - 0.0044 16.7 0.1 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) RTP1_C1 PF10363.9 EGB10001.1 - 0.0055 16.9 1.5 6.5 7.0 0.0 3.8 2 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGB10001.1 - 0.025 15.1 4.7 6.1 7.5 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat ParcG PF10274.9 EGB10001.1 - 0.043 13.9 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Parkin co-regulated protein Arm PF00514.23 EGB10002.1 - 4.1e-93 302.9 17.7 1.4e-13 50.4 0.0 8.9 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGB10002.1 - 1.1e-27 96.1 4.1 6e-10 39.4 0.1 6.5 5 1 2 7 7 7 6 HEAT-like repeat HEAT_2 PF13646.6 EGB10002.1 - 8.1e-26 90.2 0.7 3.5e-09 36.9 0.1 5.7 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 EGB10002.1 - 5.4e-22 76.0 5.2 6.3e-05 22.9 0.0 8.2 8 0 0 8 8 8 4 HEAT repeat IBB PF01749.20 EGB10002.1 - 3.3e-21 75.5 4.1 3.3e-21 75.5 4.1 2.3 3 0 0 3 3 2 1 Importin beta binding domain Arm_3 PF16186.5 EGB10002.1 - 6.3e-19 67.3 1.1 2.1e-18 65.6 1.1 1.9 1 0 0 1 1 1 1 Atypical Arm repeat Arm_2 PF04826.13 EGB10002.1 - 1.6e-07 31.0 0.0 0.018 14.5 0.0 3.4 1 1 2 4 4 4 2 Armadillo-like HEAT_PBS PF03130.16 EGB10002.1 - 3.4e-07 30.3 0.5 1.3 9.9 0.0 5.7 6 0 0 6 6 5 2 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 EGB10002.1 - 5.4e-06 26.5 0.1 4.6 7.5 0.0 5.0 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 EGB10002.1 - 1.5e-05 25.1 0.0 0.19 11.8 0.0 4.3 4 1 0 4 4 4 1 V-ATPase subunit H Cnd1 PF12717.7 EGB10002.1 - 4.1e-05 23.7 0.0 3.1 7.8 0.0 4.3 1 1 4 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGB10002.1 - 6.3e-05 21.7 0.0 0.035 12.7 0.0 3.0 1 1 1 2 2 2 2 Adaptin N terminal region CTNNBL PF08216.11 EGB10002.1 - 0.01 16.0 4.7 16 5.7 0.0 5.1 6 0 0 6 6 5 0 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 EGB10002.1 - 0.021 14.2 0.0 0.075 12.4 0.0 1.8 2 0 0 2 2 2 0 Mo25-like Rabaptin PF03528.15 EGB10002.1 - 0.022 13.5 0.8 0.035 12.8 0.8 1.2 1 0 0 1 1 1 0 Rabaptin Atx10homo_assoc PF09759.9 EGB10002.1 - 0.076 13.0 0.0 4.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain ALG11_N PF15924.5 EGB10003.1 - 2.2e-69 233.7 0.0 2.7e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGB10003.1 - 8.4e-27 93.8 0.0 1.2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGB10003.1 - 1.4e-12 48.2 1.0 3.1e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGB10003.1 - 8.7e-05 22.6 0.0 0.00018 21.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EGB10003.1 - 0.00049 20.4 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SH3_3 PF08239.11 EGB10005.1 - 8.5e-05 22.8 0.2 0.00039 20.6 0.1 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain PH PF00169.29 EGB10006.1 - 1.3e-14 54.5 0.0 2.5e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 PH domain Dynamin_N PF00350.23 EGB10006.1 - 5.6e-14 52.5 0.0 2.4e-12 47.2 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB10006.1 - 5.8e-10 39.3 0.0 1.2e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 EGB10006.1 - 4.7e-07 30.4 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Roc PF08477.13 EGB10006.1 - 3.8e-05 23.9 0.2 0.88 9.8 0.0 3.3 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGB10006.1 - 6.9e-05 22.5 0.0 0.00065 19.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PH_11 PF15413.6 EGB10006.1 - 0.0024 18.2 0.2 0.11 12.9 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain FeoB_N PF02421.18 EGB10006.1 - 0.011 15.2 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B PH_8 PF15409.6 EGB10006.1 - 0.013 15.8 0.4 0.038 14.3 0.4 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain RsgA_GTPase PF03193.16 EGB10006.1 - 0.016 15.2 0.6 7.2 6.5 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase T2SSG PF08334.11 EGB10006.1 - 0.037 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G PH_9 PF15410.6 EGB10006.1 - 0.043 14.2 0.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain cobW PF02492.19 EGB10006.1 - 0.09 12.4 0.4 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 EGB10006.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 EGB10006.1 - 0.17 11.5 0.2 16 5.0 0.0 2.6 3 0 0 3 3 3 0 Ras family CAP_N PF01213.19 EGB10006.1 - 0.5 9.8 4.3 3 7.2 2.1 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ATP-grasp_4 PF13535.6 EGB10007.1 - 3.5e-09 36.5 0.0 5.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGB10007.1 - 3e-06 27.2 0.2 4.5e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 EGB10007.1 - 0.00028 21.0 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 EGB10007.1 - 0.0051 16.9 0.0 0.0098 16.0 0.0 1.5 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 EGB10007.1 - 0.073 12.8 0.0 0.36 10.6 0.0 2.1 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Acetyltransf_1 PF00583.25 EGB10008.1 - 1.4e-13 51.1 0.0 2.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGB10008.1 - 2.1e-09 37.4 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB10008.1 - 2.2e-09 37.6 0.0 3.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB10008.1 - 2e-08 34.1 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGB10008.1 - 0.0001 22.4 0.1 0.0002 21.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGB10008.1 - 0.0099 16.0 0.1 0.013 15.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EGB10008.1 - 0.047 13.3 0.0 0.091 12.4 0.0 1.4 2 0 0 2 2 2 0 MOZ/SAS family Mlh1_C PF16413.5 EGB10009.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus EF-hand_5 PF13202.6 EGB10010.1 - 1.9e-09 36.6 0.0 1.1e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB10010.1 - 3e-09 36.1 0.0 2e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB10010.1 - 4.3e-09 35.3 0.0 1.4e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB10010.1 - 4e-07 30.4 0.0 9.7e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 EF-hand domain pair DUF4908 PF16252.5 EGB10010.1 - 0.0076 15.8 7.2 0.05 13.2 5.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4908) EF-hand_8 PF13833.6 EGB10010.1 - 0.012 15.5 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair MFS_MOT1 PF16983.5 EGB10011.1 - 1.5e-49 167.0 26.6 1.3e-26 93.1 9.8 3.0 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 EGB10011.1 - 0.0011 17.7 8.9 0.0017 17.1 8.9 1.4 1 0 0 1 1 1 1 Permease family ABC_tran PF00005.27 EGB10012.1 - 3e-17 63.4 0.0 8.7e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB10012.1 - 0.00051 20.0 0.0 0.096 12.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB10012.1 - 0.00059 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGB10012.1 - 0.00096 19.6 0.1 0.0016 18.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGB10012.1 - 0.0015 18.2 0.5 0.0047 16.6 0.5 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB10012.1 - 0.0019 18.5 0.1 0.0041 17.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB10012.1 - 0.014 16.0 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGB10012.1 - 0.016 14.8 0.8 0.036 13.6 0.6 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB10012.1 - 0.016 15.7 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB10012.1 - 0.057 13.6 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB10012.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGB10012.1 - 0.098 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 EGB10012.1 - 0.1 12.6 0.9 0.29 11.1 0.9 1.8 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGB10012.1 - 0.22 11.2 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGB10012.1 - 0.3 10.7 0.9 0.51 9.9 0.2 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ion_trans PF00520.31 EGB10013.1 - 6.9e-21 74.6 7.8 1e-20 74.0 7.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB10013.1 - 7.5e-11 41.8 2.8 2.1e-10 40.4 2.8 1.8 1 0 0 1 1 1 1 Ion channel Ureidogly_lyase PF04115.12 EGB10014.1 - 1.4e-05 24.9 0.0 5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Ureidoglycolate lyase ABC1 PF03109.16 EGB10015.1 - 2e-30 105.4 0.0 4.1e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGB10015.1 - 0.0068 15.8 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGB10015.1 - 0.0084 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family CH PF00307.31 EGB10015.1 - 0.19 11.9 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain Queuosine_synth PF02547.15 EGB10016.1 - 2.2e-92 309.7 0.0 2.5e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueH PF02677.14 EGB10017.1 - 3.1e-60 203.2 0.3 3.9e-60 202.9 0.3 1.1 1 0 0 1 1 1 1 Epoxyqueuosine reductase QueH ArfGap PF01412.18 EGB10018.1 - 4.9e-19 68.5 1.0 5.2e-19 68.4 1.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 EGB10018.1 - 0.28 11.4 2.5 1 9.5 0.2 2.0 2 0 0 2 2 2 0 B-box zinc finger PARP PF00644.20 EGB10019.1 - 2.9e-18 66.2 0.0 2.8e-17 63.0 0.0 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Metallophos PF00149.28 EGB10020.1 - 6.2e-34 118.3 0.1 7.5e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGB10020.1 - 3e-06 27.6 0.0 7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TerC PF03741.16 EGB10021.1 - 2.1e-35 122.0 0.7 2.9e-35 121.6 0.7 1.2 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF3961 PF13106.6 EGB10021.1 - 0.13 11.9 1.1 9.8 5.9 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) HhH-GPD PF00730.25 EGB10022.1 - 1.1e-19 70.9 0.0 1.7e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGB10022.1 - 3.6e-06 26.6 0.1 1.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EGB10022.1 - 1.4 9.3 9.6 1.7 9.1 5.7 2.4 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III UDPGP PF01704.18 EGB10023.1 - 4.1e-07 29.0 0.0 7.2e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ADH_N_2 PF16884.5 EGB10024.1 - 3.1e-16 59.2 0.0 8.3e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGB10024.1 - 4.1e-11 43.0 2.0 6.9e-11 42.2 2.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGB10024.1 - 0.00029 21.9 0.1 0.00066 20.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GFO_IDH_MocA PF01408.22 EGB10026.1 - 2.7e-25 89.5 0.3 5.1e-25 88.6 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGB10026.1 - 3.6e-08 33.4 0.0 7.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 EGB10026.1 - 0.00014 22.4 0.1 0.00056 20.4 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EGB10026.1 - 0.00087 19.6 0.1 0.002 18.4 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGB10026.1 - 0.029 14.4 0.0 0.073 13.1 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGB10026.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGB10026.1 - 0.071 13.5 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Rossmann-like PF10727.9 EGB10026.1 - 0.11 12.4 0.2 0.27 11.1 0.2 1.7 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_3 PF03447.16 EGB10026.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGB10026.1 - 0.19 12.0 0.6 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain SBF PF01758.16 EGB10027.1 - 2.5e-29 102.4 9.6 1e-28 100.3 8.8 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 EGB10027.1 - 3.1e-08 33.3 14.4 4.8e-08 32.7 14.4 1.4 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) E1-E2_ATPase PF00122.20 EGB10027.1 - 0.004 16.7 0.0 0.004 16.7 0.0 3.2 2 1 2 4 4 4 1 E1-E2 ATPase EptA_B_N PF08019.12 EGB10027.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.9 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB DUF3382 PF11862.8 EGB10027.1 - 1.2 9.5 9.7 2.5 8.4 3.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) Mem_trans PF03547.18 EGB10027.1 - 1.5 7.1 9.8 5.8 5.2 5.2 2.6 2 1 0 2 2 2 0 Membrane transport protein zf-RING_2 PF13639.6 EGB10028.1 - 1.2e-12 47.9 8.5 1.2e-12 47.9 8.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGB10028.1 - 5.2e-11 42.1 1.7 1.6e-10 40.5 1.7 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGB10028.1 - 6.9e-09 35.9 5.1 1.4e-08 34.9 5.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGB10028.1 - 1.3e-07 31.3 3.4 1.3e-07 31.3 3.4 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB10028.1 - 2.7e-07 30.3 4.0 6e-07 29.2 4.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGB10028.1 - 5.1e-07 29.5 6.1 5.1e-07 29.5 6.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGB10028.1 - 5.8e-07 29.3 8.4 5.8e-07 29.3 8.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGB10028.1 - 8.5e-06 25.5 5.6 8.5e-06 25.5 5.6 3.0 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGB10028.1 - 6.1e-05 23.0 2.7 0.00017 21.6 2.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGB10028.1 - 0.00011 22.1 2.2 0.00011 22.1 2.2 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3H2C3 PF17122.5 EGB10028.1 - 0.022 14.8 2.3 0.051 13.6 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 EGB10028.1 - 0.3 11.2 4.3 0.64 10.2 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain Peptidase_S8 PF00082.22 EGB10029.1 - 1.1e-33 116.9 11.3 1.8e-33 116.1 11.3 1.3 1 0 0 1 1 1 1 Subtilase family Peptidase_S8_N PF16361.5 EGB10029.1 - 1.4e-05 25.6 0.1 7.2e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 N-terminal of Subtilase family PDZ_6 PF17820.1 EGB10029.1 - 0.0019 18.0 0.1 0.045 13.6 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Peptidase_S8 PF00082.22 EGB10030.1 - 6e-34 117.7 11.7 9.6e-34 117.0 11.7 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_S8_N PF16361.5 EGB10030.1 - 8.4e-06 26.3 0.2 5.1e-05 23.8 0.2 2.1 1 1 0 1 1 1 1 N-terminal of Subtilase family DHO_dh PF01180.21 EGB10031.1 - 5.6e-76 255.6 0.0 8.5e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 EGB10031.1 - 0.0015 18.0 0.2 0.0027 17.2 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Trypsin_2 PF13365.6 EGB10032.1 - 2.9e-32 112.7 3.0 2.9e-32 112.7 3.0 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGB10032.1 - 5e-15 55.9 0.0 7.5e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EGB10032.1 - 7.1e-12 45.5 1.2 1.4e-11 44.5 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGB10032.1 - 1.9e-08 34.0 4.0 6.7e-08 32.3 1.1 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EGB10032.1 - 9.6e-07 29.1 0.0 3.5e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Peptidase_S32 PF05579.13 EGB10032.1 - 0.0042 16.3 0.8 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 EGB10032.1 - 0.055 12.1 0.6 0.1 11.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S29 PF02907.15 EGB10032.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S3 PF00944.19 EGB10032.1 - 0.1 12.4 0.5 0.28 11.0 0.2 1.8 2 0 0 2 2 2 0 Alphavirus core protein ABC_tran PF00005.27 EGB10033.1 - 1.3e-27 96.9 0.0 1.8e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB10033.1 - 0.00014 21.7 0.2 0.061 13.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB10033.1 - 0.00075 19.4 0.2 0.0012 18.7 0.2 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EGB10033.1 - 0.0011 19.3 0.9 0.0048 17.2 0.8 2.1 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 EGB10033.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 EGB10033.1 - 0.0053 17.2 0.1 0.0082 16.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGB10033.1 - 0.0087 15.8 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGB10033.1 - 0.011 15.1 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 EGB10033.1 - 0.012 15.7 0.4 0.022 14.8 0.4 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3584 PF12128.8 EGB10033.1 - 0.014 12.9 0.4 0.13 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SMC_N PF02463.19 EGB10033.1 - 0.041 13.3 0.2 2 7.8 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain PRK PF00485.18 EGB10033.1 - 0.057 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 EGB10033.1 - 0.068 12.7 3.6 0.92 9.0 3.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB10033.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB10033.1 - 0.097 13.2 0.1 0.16 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EGB10033.1 - 0.1 12.5 0.4 0.2 11.5 0.4 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 EGB10033.1 - 0.12 12.8 0.8 0.9 10.0 0.7 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGB10033.1 - 0.14 11.9 2.8 0.22 11.2 2.4 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGB10033.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 EGB10033.1 - 0.16 11.5 0.7 0.27 10.8 0.7 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pro_isomerase PF00160.21 EGB10034.1 - 3.3e-35 121.7 0.0 4.5e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF498 PF04430.14 EGB10034.1 - 3.1e-24 85.1 0.0 4.7e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pkinase PF00069.25 EGB10035.1 - 1.6e-23 83.5 0.0 1.9e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10035.1 - 2.9e-14 53.0 0.0 3.3e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB10035.1 - 0.00094 19.2 0.0 0.0011 18.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Arm PF00514.23 EGB10036.1 - 2.3e-42 141.8 8.5 2.4e-09 36.9 0.1 5.0 5 0 0 5 5 5 5 Armadillo/beta-catenin-like repeat OAM_alpha PF16552.5 EGB10036.1 - 0.0018 18.2 0.0 47 3.9 0.0 4.2 2 2 1 4 4 4 0 D-ornithine 4,5-aminomutase alpha-subunit HEAT_EZ PF13513.6 EGB10036.1 - 0.0018 18.7 13.9 0.48 11.0 1.3 3.7 2 1 2 4 4 4 4 HEAT-like repeat Atx10homo_assoc PF09759.9 EGB10036.1 - 0.025 14.6 0.1 29 4.8 0.0 3.4 2 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain PUD PF03714.14 EGB10036.1 - 0.028 15.3 2.5 0.1 13.5 0.1 2.4 2 1 1 3 3 3 0 Bacterial pullanase-associated domain Aconitase_B_N PF11791.8 EGB10036.1 - 0.032 14.3 0.1 66 3.5 0.0 4.0 2 2 2 4 4 4 0 Aconitate B N-terminal domain Aa_trans PF01490.18 EGB10037.1 - 1.3e-14 53.7 0.1 1.7e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.27 EGB10039.1 - 1.7e-26 93.4 0.0 2.1e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB10039.1 - 2.5e-11 44.0 0.0 1.5e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB10039.1 - 0.00078 18.9 0.0 0.29 10.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB10039.1 - 0.0029 17.4 1.5 0.0077 16.0 1.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EGB10039.1 - 0.0081 15.9 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGB10039.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EGB10039.1 - 0.14 12.5 0.1 0.2 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB10039.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Trypsin_2 PF13365.6 EGB10040.1 - 1.4e-28 100.7 1.2 2.2e-28 100.0 1.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGB10040.1 - 5.2e-12 46.1 0.0 8.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EGB10040.1 - 1.6e-09 37.9 0.1 5e-09 36.4 0.1 1.9 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGB10040.1 - 3.5e-05 24.0 0.1 0.00014 22.1 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGB10040.1 - 3.6e-05 23.5 5.7 9.7e-05 22.1 0.0 3.6 5 0 0 5 5 5 1 PDZ domain Tricorn_PDZ PF14685.6 EGB10040.1 - 0.0074 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Peptidase_S29 PF02907.15 EGB10040.1 - 0.0098 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 EGB10040.1 - 0.23 10.0 0.8 0.5 8.9 0.3 1.7 2 0 0 2 2 2 0 Peptidase S46 DUF2012 PF09430.10 EGB10041.1 - 2.3e-20 73.0 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 EGB10041.1 - 0.0025 18.1 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGB10041.1 - 0.0027 17.7 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 CarboxypepD_reg-like domain fn3_3 PF14686.6 EGB10041.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II Acid_PPase PF12689.7 EGB10042.1 - 1.6e-19 70.4 0.0 1.8e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase PHZA_PHZB PF03284.13 EGB10042.1 - 0.045 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B EGF_2 PF07974.13 EGB10043.1 - 1.2e-10 41.5 57.5 7.8e-05 23.0 10.2 5.7 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 EGB10043.1 - 0.024 14.8 6.4 0.024 14.8 6.4 4.5 4 1 0 4 4 4 0 Laminin EGF domain GSIII_N PF12437.8 EGB10044.1 - 2.6e-50 170.2 0.0 4e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EGB10044.1 - 4.7e-32 110.3 0.0 1.3e-31 108.9 0.0 1.7 2 0 0 2 2 2 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EGB10044.1 - 1.7e-22 79.9 0.0 3.4e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Rhodanese PF00581.20 EGB10045.1 - 4.6e-13 49.6 0.0 5e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain Sel1 PF08238.12 EGB10046.1 - 1.5e-12 47.7 0.4 4.2e-07 30.4 0.0 3.0 3 1 0 3 3 3 2 Sel1 repeat HNHc_6 PF16784.5 EGB10046.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative HNHc nuclease Asp PF00026.23 EGB10047.1 - 5.3e-30 104.9 9.8 6.3e-26 91.5 0.3 2.3 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGB10047.1 - 7.1e-12 45.4 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DnaJ PF00226.31 EGB10048.1 - 2.2e-17 62.9 0.3 2.5e-17 62.7 0.3 1.0 1 0 0 1 1 1 1 DnaJ domain AAA_26 PF13500.6 EGB10048.1 - 0.075 12.8 0.0 0.084 12.7 0.0 1.0 1 0 0 1 1 1 0 AAA domain UPF0061 PF02696.14 EGB10049.1 - 1.6 7.4 5.6 2.9 6.6 5.6 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family IZUMO PF15005.6 EGB10049.1 - 6.8 7.2 7.7 11 6.6 5.3 2.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated SAM_2 PF07647.17 EGB10050.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ADH_zinc_N_2 PF13602.6 EGB10051.1 - 2.7e-16 60.8 0.0 1.2e-15 58.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGB10051.1 - 2.2e-11 43.8 0.1 3.9e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB10051.1 - 9.4e-10 38.4 0.6 1e-08 35.0 0.4 2.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGB10051.1 - 0.045 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Dynamin_M PF01031.20 EGB10052.1 - 2.2e-56 191.2 0.0 3.3e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGB10052.1 - 8.6e-43 146.3 0.0 1.1e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGB10052.1 - 5.1e-11 42.6 0.0 8.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGB10052.1 - 0.0032 17.5 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EGB10052.1 - 0.095 12.0 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Aminotran_1_2 PF00155.21 EGB10053.1 - 1.6e-26 93.3 0.0 5.6e-26 91.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EGB10053.1 - 0.00019 20.5 0.0 0.00052 19.0 0.0 1.8 1 1 1 2 2 2 1 Allinase Adeno_PIX PF03955.14 EGB10055.1 - 0.035 14.3 1.5 0.05 13.8 1.5 1.2 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) URO-D PF01208.17 EGB10056.1 - 5.9e-109 364.4 0.0 7.4e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TPP_enzyme_C PF02775.21 EGB10056.1 - 0.065 13.0 0.0 3.4 7.4 0.1 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DNA_binding_1 PF01035.20 EGB10057.1 - 1.4e-19 70.0 0.0 1.6e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ASH PF15780.5 EGB10058.1 - 1e-74 246.9 26.1 8.2e-06 26.0 0.0 28.4 31 1 0 31 31 31 19 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGB10058.1 - 7.9e-23 80.4 0.0 0.049 13.5 0.0 14.5 17 0 0 17 17 17 4 MSP (Major sperm protein) domain DUF1573 PF07610.11 EGB10058.1 - 8.4e-18 64.2 0.0 1.1 9.3 0.0 16.0 20 0 0 20 20 20 1 Protein of unknown function (DUF1573) PapD-like PF14874.6 EGB10058.1 - 2.9e-15 56.3 9.4 0.01 16.0 0.0 13.2 16 0 0 16 16 16 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 EGB10058.1 - 1.2e-13 51.1 2.2 0.89 9.9 0.0 13.2 17 0 0 17 17 17 1 Transmembrane protein 131-like MYCBPAP PF14646.6 EGB10058.1 - 6.3e-11 41.9 0.0 5.7 5.8 0.0 8.8 11 0 0 11 11 11 5 MYCBP-associated protein family fn3_5 PF06280.12 EGB10058.1 - 4.1e-07 30.7 0.1 4.4 8.0 0.1 9.4 11 0 0 11 11 11 1 Fn3-like domain Fn3-like PF14310.6 EGB10058.1 - 2.5e-05 24.3 0.6 2.8 8.1 0.0 7.0 8 0 0 8 8 8 1 Fibronectin type III-like domain Ribosomal_L24e PF01246.20 EGB10059.1 - 2.8e-24 85.1 0.4 2.8e-24 85.1 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e DUF563 PF04577.14 EGB10060.1 - 8.8e-15 55.4 0.0 1.2e-13 51.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF563) TPR_2 PF07719.17 EGB10060.1 - 0.00021 21.1 4.5 0.02 15.0 0.7 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB10060.1 - 0.0045 16.7 0.2 0.22 11.4 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10060.1 - 0.012 15.7 0.5 2.7 8.4 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB10060.1 - 0.013 15.4 4.7 0.039 14.0 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10060.1 - 0.013 15.7 6.3 0.013 15.7 6.3 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB10060.1 - 0.045 13.6 0.4 0.045 13.6 0.4 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat APC_r PF05923.12 EGB10060.1 - 0.092 12.5 0.3 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 APC repeat TPR_6 PF13174.6 EGB10060.1 - 3.3 8.5 5.3 39 5.2 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat IspD PF01128.19 EGB10061.1 - 2e-58 197.8 0.1 2.3e-58 197.5 0.1 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 EGB10061.1 - 4.9e-14 53.0 0.5 8.8e-14 52.2 0.5 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain V-SNARE_C PF12352.8 EGB10062.1 - 4.2e-09 36.5 1.4 6.2e-09 36.0 1.4 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Aldo_ket_red PF00248.21 EGB10063.1 - 5.3e-57 193.3 0.0 6.4e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_31 PF13560.6 EGB10063.1 - 1.1 9.7 5.4 0.57 10.6 2.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LamB_YcsF PF03746.16 EGB10064.1 - 4.1e-87 291.8 3.4 4.8e-87 291.6 3.4 1.0 1 0 0 1 1 1 1 LamB/YcsF family CLPTM1 PF05602.12 EGB10065.1 - 2e-63 214.9 0.0 2.5e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EGB10065.1 - 0.0094 15.7 0.8 0.21 11.4 0.1 2.6 2 0 0 2 2 2 1 PQ loop repeat Rnk_N PF14760.6 EGB10065.1 - 0.2 12.1 1.3 0.4 11.2 1.3 1.5 1 0 0 1 1 1 0 Rnk N-terminus Tim17 PF02466.19 EGB10066.1 - 7.6e-31 106.8 3.6 9e-31 106.5 3.6 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DnaJ PF00226.31 EGB10067.1 - 7.5e-17 61.2 0.4 7.5e-17 61.2 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain SCP2 PF02036.17 EGB10068.1 - 0.0014 19.1 0.0 0.013 15.9 0.0 2.6 2 0 0 2 2 2 1 SCP-2 sterol transfer family DnaJ_C PF01556.18 EGB10069.1 - 1.4e-37 129.0 0.1 2e-37 128.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB10069.1 - 3e-22 78.5 0.3 5e-22 77.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGB10069.1 - 1.3e-07 31.8 2.4 3.9e-07 30.3 2.4 1.7 1 0 0 1 1 1 1 DnaJ central domain Ribosomal_L21e PF01157.18 EGB10069.1 - 0.61 10.0 2.5 0.59 10.0 0.2 2.1 3 0 0 3 3 3 0 Ribosomal protein L21e SelR PF01641.18 EGB10070.1 - 2.6e-47 159.8 0.0 2.9e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EGB10070.1 - 0.017 15.1 0.1 0.064 13.3 0.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon Tnp_zf-ribbon_2 PF13842.6 EGB10070.1 - 0.038 14.8 1.8 5.7 7.8 0.0 2.7 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DUF678 PF05077.12 EGB10070.1 - 0.09 12.9 0.1 12 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) TF_Zn_Ribbon PF08271.12 EGB10070.1 - 0.11 12.0 3.8 1.2 8.8 0.1 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding SRP54 PF00448.22 EGB10071.1 - 2.3e-77 259.1 0.0 5e-77 258.0 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGB10071.1 - 7.6e-30 103.5 1.1 7.6e-30 103.5 1.1 3.3 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 EGB10071.1 - 1.3e-19 70.1 4.7 3.5e-19 68.8 4.7 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 EGB10071.1 - 4.3e-06 27.2 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EGB10071.1 - 6.1e-06 26.1 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EGB10071.1 - 6.7e-06 25.8 3.5 0.00029 20.5 1.9 3.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGB10071.1 - 1.2e-05 24.7 0.1 2.6e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EGB10071.1 - 7.4e-05 22.9 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 EGB10071.1 - 7.9e-05 22.2 0.0 4.5 6.7 0.0 3.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 EGB10071.1 - 0.00073 18.6 0.1 0.0065 15.5 0.1 2.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EGB10071.1 - 0.0015 18.8 0.9 0.0064 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EGB10071.1 - 0.0021 18.1 0.2 0.0059 16.6 0.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 EGB10071.1 - 0.0043 17.5 0.0 0.0043 17.5 0.0 2.8 3 1 0 3 3 3 1 AAA domain CLP1_P PF16575.5 EGB10071.1 - 0.0054 16.6 0.2 0.59 9.9 0.0 2.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 EGB10071.1 - 0.0061 16.6 2.5 0.031 14.4 0.4 2.9 2 1 0 2 2 1 1 50S ribosome-binding GTPase APS_kinase PF01583.20 EGB10071.1 - 0.0082 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 EGB10071.1 - 0.017 15.4 0.0 0.074 13.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGB10071.1 - 0.022 15.1 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EGB10071.1 - 0.035 13.4 0.5 0.46 9.7 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase ATPase PF06745.13 EGB10071.1 - 0.037 13.4 0.1 0.12 11.7 0.1 1.9 1 1 0 1 1 1 0 KaiC Arf PF00025.21 EGB10071.1 - 0.045 13.2 0.1 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family NB-ARC PF00931.22 EGB10071.1 - 0.046 12.9 0.0 0.22 10.7 0.0 2.1 1 1 0 1 1 1 0 NB-ARC domain CbiA PF01656.23 EGB10071.1 - 0.082 13.0 0.0 0.33 11.0 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EGB10071.1 - 0.088 12.5 0.1 0.28 10.9 0.0 1.9 2 1 0 2 2 1 0 AAA domain Phage_TAC_11 PF11836.8 EGB10071.1 - 0.098 12.8 0.0 3.1 8.0 0.0 2.8 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 DUF373 PF04123.13 EGB10071.1 - 0.22 10.9 0.6 0.34 10.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) AAA PF00004.29 EGB10071.1 - 0.66 10.4 4.5 0.76 10.2 0.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) GED PF02212.18 EGB10071.1 - 2.9 8.1 7.1 9.9 6.4 1.1 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain WD40 PF00400.32 EGB10072.1 - 2e-38 129.7 1.5 4.2e-09 36.9 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB10072.1 - 1.2e-11 44.8 0.0 0.082 13.2 0.0 4.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB10072.1 - 2.2e-05 23.6 1.5 0.54 9.2 0.0 3.6 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGB10072.1 - 0.00048 19.5 0.0 4.9 6.4 0.0 3.3 2 2 2 4 4 4 2 WD40-like domain Nup160 PF11715.8 EGB10072.1 - 0.015 14.0 0.0 7.8 5.0 0.0 2.9 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Frtz PF11768.8 EGB10072.1 - 0.016 13.5 0.0 2.9 6.1 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1652 PF07865.11 EGB10072.1 - 0.018 14.8 0.0 21 5.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) PQQ_3 PF13570.6 EGB10072.1 - 4.1 8.0 10.1 1 10.0 0.2 3.5 3 1 0 3 3 3 0 PQQ-like domain polyprenyl_synt PF00348.17 EGB10073.1 - 1.6e-61 207.6 0.0 1.9e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TFB6 PF17110.5 EGB10074.1 - 8 6.2 8.2 14 5.4 8.2 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Pkinase PF00069.25 EGB10075.1 - 1.2e-32 113.3 0.0 1.9e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10075.1 - 8.3e-23 81.0 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Glycos_transf_2 PF00535.26 EGB10075.1 - 3.9e-08 33.3 0.0 7.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Pkinase_fungal PF17667.1 EGB10075.1 - 6.7e-05 21.8 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Glyco_tranf_2_3 PF13641.6 EGB10075.1 - 0.0012 18.7 0.4 0.0054 16.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Ion_trans_2 PF07885.16 EGB10076.1 - 2.6e-11 43.3 6.8 2.6e-11 43.3 6.8 1.6 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EGB10076.1 - 4.8e-06 26.0 2.8 7.3e-06 25.4 2.8 1.3 1 0 0 1 1 1 1 Ion transport protein RRM_DME PF15628.6 EGB10076.1 - 0.036 14.2 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 RRM in Demeter U-box PF04564.15 EGB10077.1 - 3.6e-17 62.3 0.0 3.9e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB10077.1 - 1.1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EGB10077.1 - 0.00014 21.9 0.0 0.00017 21.7 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGB10077.1 - 0.00032 20.7 0.0 0.00042 20.3 0.0 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGB10077.1 - 0.14 12.3 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING adh_short PF00106.25 EGB10078.1 - 2e-37 128.6 0.1 2.8e-37 128.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB10078.1 - 1.9e-23 83.2 0.8 2.4e-23 82.9 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB10078.1 - 1.9e-06 27.9 0.1 2.9e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EGB10078.1 - 0.0097 15.7 0.1 0.042 13.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF5058 PF16481.5 EGB10078.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) eIF-5_eIF-2B PF01873.17 EGB10079.1 - 2.3e-34 117.7 0.0 4.2e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EGB10079.1 - 2e-18 66.3 0.0 2e-18 66.3 0.0 3.4 3 1 0 3 3 1 1 eIF4-gamma/eIF5/eIF2-epsilon BUD22 PF09073.10 EGB10079.1 - 9.3e-06 25.2 25.6 1.3e-05 24.8 25.6 1.1 1 0 0 1 1 1 1 BUD22 TAF4 PF05236.14 EGB10079.1 - 0.0074 16.1 15.6 0.011 15.6 15.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Zn_Tnp_IS1595 PF12760.7 EGB10079.1 - 0.012 15.5 0.5 0.036 14.0 0.5 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rtf2 PF04641.12 EGB10079.1 - 0.051 12.9 21.2 0.076 12.4 21.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger CKAP2_C PF15297.6 EGB10079.1 - 0.14 11.3 15.8 0.2 10.7 15.8 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Zip PF02535.22 EGB10079.1 - 0.2 10.9 8.2 0.27 10.4 8.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mitofilin PF09731.9 EGB10079.1 - 0.25 10.2 19.4 0.32 9.8 19.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SLC12 PF03522.15 EGB10079.1 - 0.28 10.2 10.2 0.37 9.8 10.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EGB10079.1 - 0.57 8.9 12.4 0.8 8.4 12.4 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 EGB10079.1 - 0.59 8.8 8.3 0.72 8.5 8.3 1.1 1 0 0 1 1 1 0 Raftlin FAM91_C PF14648.6 EGB10079.1 - 0.64 8.8 2.8 0.99 8.2 2.8 1.3 1 0 0 1 1 1 0 FAM91 C-terminus CDC27 PF09507.10 EGB10079.1 - 0.83 9.0 31.9 1.2 8.4 31.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nha1_C PF08619.10 EGB10079.1 - 0.97 8.6 25.0 1.3 8.1 25.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SAPS PF04499.15 EGB10079.1 - 1.1 8.0 11.3 1.4 7.6 11.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2151 PF10221.9 EGB10079.1 - 2.4 6.6 15.2 3.2 6.2 15.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Rrn6 PF10214.9 EGB10079.1 - 2.9 6.3 6.3 3.7 5.9 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RNase_H2_suC PF08615.11 EGB10079.1 - 3.1 7.9 9.3 1.1e+02 2.9 9.3 2.7 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TERB2 PF15101.6 EGB10079.1 - 3.4 7.7 15.7 0.099 12.7 2.6 2.2 1 1 1 2 2 2 0 Telomere-associated protein TERB2 Nop14 PF04147.12 EGB10079.1 - 4.3 5.4 33.1 6.1 4.9 33.1 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 EGB10079.1 - 4.5 5.3 8.4 5.9 4.9 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 EGB10079.1 - 5.8 6.9 5.7 9.1 6.3 5.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PMSR PF01625.21 EGB10081.1 - 3.4e-32 111.7 0.1 4.9e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DBD_Tnp_Mut PF03108.15 EGB10081.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 MuDR family transposase EF-hand_6 PF13405.6 EGB10082.1 - 3.1e-10 39.1 0.0 0.00013 21.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGB10082.1 - 4.8e-10 39.8 0.0 1.3e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB10082.1 - 1.2e-09 37.0 0.0 0.0012 18.2 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB10082.1 - 1.4e-08 33.8 0.2 7.3e-05 22.1 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB10082.1 - 9.7e-06 25.4 0.0 0.12 12.2 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain pair Reticulon PF02453.17 EGB10082.1 - 0.065 13.2 1.8 2.8 7.9 0.9 2.4 2 0 0 2 2 2 0 Reticulon ERAP1_C PF11838.8 EGB10082.1 - 0.087 12.4 3.2 0.83 9.1 0.4 2.2 2 0 0 2 2 2 0 ERAP1-like C-terminal domain CPBP PF02517.16 EGB10082.1 - 0.13 12.7 3.1 0.47 10.8 0.1 2.5 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Tyrosinase PF00264.20 EGB10083.1 - 1.1e-09 38.9 5.8 9.7e-06 26.0 2.0 2.6 2 0 0 2 2 2 2 Common central domain of tyrosinase TerY_C PF15616.6 EGB10083.1 - 0.16 12.1 1.4 0.51 10.5 0.1 2.1 2 0 0 2 2 2 0 TerY-C metal binding domain LRR_6 PF13516.6 EGB10084.1 - 2e-15 55.4 6.1 0.14 12.3 0.1 8.5 8 0 0 8 8 8 5 Leucine Rich repeat Dymeclin PF09742.9 EGB10085.1 - 1.4e-172 575.4 0.0 1.9e-172 575.0 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 EGB10085.1 - 2.1e-165 552.1 0.0 1.4e-139 466.8 0.0 2.1 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Nuc_sug_transp PF04142.15 EGB10085.1 - 1.5e-05 24.3 1.1 3.7e-05 23.0 1.1 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 EGB10085.1 - 0.00062 18.8 11.8 0.033 13.1 11.8 2.2 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like DUF2183 PF09949.9 EGB10085.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) UAA PF08449.11 EGB10085.1 - 0.11 11.7 5.0 0.24 10.6 5.0 1.5 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.16 EGB10085.1 - 0.91 8.8 12.0 6.3 6.1 12.0 2.2 1 1 0 1 1 1 0 Triose-phosphate Transporter family UTP25 PF06862.12 EGB10086.1 - 1e-88 298.2 0.0 1.6e-88 297.6 0.0 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EGB10086.1 - 0.0043 16.8 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase BUD22 PF09073.10 EGB10086.1 - 0.0099 15.3 17.6 0.018 14.4 17.6 1.3 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 EGB10086.1 - 0.022 13.1 10.8 0.032 12.6 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Gag_spuma PF03276.14 EGB10086.1 - 0.025 13.1 0.3 0.035 12.5 0.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein SDA1 PF05285.12 EGB10086.1 - 0.034 13.6 21.2 0.053 13.0 21.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGB10086.1 - 0.13 10.5 23.4 0.18 10.0 23.4 1.1 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 EGB10086.1 - 0.49 9.9 12.9 0.75 9.3 12.9 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein CNDH2_C PF16858.5 EGB10086.1 - 1 9.2 8.6 2 8.2 8.6 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Lin-8 PF03353.15 EGB10086.1 - 4.5 6.7 8.6 6.8 6.2 8.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cwf_Cwc_15 PF04889.12 EGB10086.1 - 4.6 6.9 18.9 9.5 5.9 18.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein cNMP_binding PF00027.29 EGB10087.1 - 2.2e-12 46.9 0.0 4.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain WD40 PF00400.32 EGB10088.1 - 1.8e-11 44.4 7.0 0.0005 20.8 0.6 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB10088.1 - 0.0032 17.7 1.0 2.1 8.7 0.0 4.1 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Thiolase_N PF00108.23 EGB10089.1 - 5.7e-62 209.4 9.5 1.4e-61 208.1 9.5 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGB10089.1 - 1.5e-40 137.7 0.6 4.2e-40 136.2 0.6 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGB10089.1 - 2e-06 27.6 0.6 5.7e-06 26.1 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain LRR_4 PF12799.7 EGB10090.1 - 4.8e-12 45.9 6.4 0.00049 20.4 1.6 4.3 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB10090.1 - 2.9e-09 36.7 0.0 1.2e-08 34.6 0.0 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EGB10090.1 - 1.1e-07 31.5 3.9 1.1e-07 31.5 3.9 2.7 2 1 1 3 3 3 1 Leucine rich repeat Histone_H2A_C PF16211.5 EGB10091.1 - 1.5e-20 72.7 1.7 3.8e-20 71.3 1.7 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB10091.1 - 5e-12 46.3 0.0 6.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB10091.1 - 0.0034 17.6 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF812 PF05667.11 EGB10092.1 - 1.6e-63 215.6 12.8 1.8e-63 215.4 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) VanY PF02557.17 EGB10092.1 - 0.024 14.5 0.1 0.055 13.3 0.1 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Jnk-SapK_ap_N PF09744.9 EGB10092.1 - 0.18 12.1 9.6 0.051 13.8 0.8 2.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Sigma70_ner PF04546.13 EGB10092.1 - 0.22 11.4 6.6 0.05 13.5 2.6 1.9 2 1 0 2 2 2 0 Sigma-70, non-essential region DUF641 PF04859.12 EGB10092.1 - 0.48 10.8 6.3 3.8 7.8 0.2 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) YabA PF06156.13 EGB10092.1 - 1.4 9.6 4.6 3.3 8.4 1.4 2.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF2203 PF09969.9 EGB10092.1 - 9.6 7.0 10.4 41 4.9 0.6 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) dsrm PF00035.26 EGB10093.1 - 0.0071 17.0 0.1 0.019 15.7 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Got1 PF04178.12 EGB10094.1 - 4.4e-29 101.2 11.6 5.7e-29 100.8 11.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family UbiA PF01040.18 EGB10094.1 - 0.0036 16.6 2.0 0.0036 16.6 2.0 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF3325 PF11804.8 EGB10094.1 - 0.026 14.7 2.2 0.031 14.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Phage_holin_3_6 PF07332.11 EGB10094.1 - 0.05 13.7 0.1 0.05 13.7 0.1 2.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SdpI PF13630.6 EGB10094.1 - 2.9 8.1 11.5 0.59 10.3 3.4 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family CCDC53 PF10152.9 EGB10095.1 - 3e-12 47.2 0.2 3e-12 47.2 0.2 4.1 3 1 0 3 3 2 1 Subunit CCDC53 of WASH complex FH2 PF02181.23 EGB10095.1 - 9e-12 44.8 0.0 3.4e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain CAP_GLY PF01302.25 EGB10095.1 - 9.9e-12 44.7 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_1 PF00036.32 EGB10095.1 - 4.5e-10 38.4 0.2 1.2e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB10095.1 - 6.1e-10 38.2 0.2 0.00057 19.6 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB10095.1 - 9.5e-09 35.6 0.1 2.1e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB10095.1 - 3.2e-05 23.2 0.2 0.14 11.7 0.0 2.6 2 0 0 2 2 2 2 EF hand cNMP_binding PF00027.29 EGB10095.1 - 0.00015 21.7 0.0 0.00041 20.4 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EF-hand_8 PF13833.6 EGB10095.1 - 0.00025 20.8 0.3 0.0024 17.7 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair PapD-like PF14874.6 EGB10095.1 - 0.0032 17.6 0.0 0.0076 16.4 0.0 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like EF-hand_4 PF12763.7 EGB10095.1 - 0.082 12.9 0.1 0.39 10.7 0.0 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand BaxI_1 PF12811.7 EGB10096.1 - 2.1 7.9 10.1 2.9 7.4 0.3 2.1 1 1 1 2 2 2 0 Bax inhibitor 1 like DSPn PF14671.6 EGB10098.1 - 5.4e-42 143.6 0.0 1.2e-41 142.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGB10098.1 - 1.9e-13 50.3 0.0 8.6e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB10098.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGB10098.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGB10098.1 - 0.045 13.7 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Lipase_3 PF01764.25 EGB10099.1 - 2.7e-13 50.0 0.0 4.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EGB10099.1 - 0.059 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 EGB10099.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peripla_BP_2 PF01497.18 EGB10101.1 - 5.6e-07 29.4 0.0 1.2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein Kelch_1 PF01344.25 EGB10102.1 - 8e-44 147.0 14.8 4.2e-08 32.6 0.2 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGB10102.1 - 7.9e-35 118.3 13.5 3.3e-05 23.7 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGB10102.1 - 1.1e-33 113.9 19.5 0.00014 21.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGB10102.1 - 1.5e-33 114.4 18.3 1.6e-07 31.4 0.4 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGB10102.1 - 1.2e-32 111.1 16.5 2.6e-05 24.3 0.2 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGB10102.1 - 6.3e-29 99.7 15.4 4.9e-05 23.2 0.1 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 EGB10102.1 - 1.3e-23 83.3 0.9 8.6e-23 80.7 0.2 2.1 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 EGB10102.1 - 7.8e-06 25.9 1.2 0.00011 22.3 0.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch RNA_pol_Rpb1_5 PF04998.17 EGB10103.1 - 1.4e-98 329.6 0.0 2.1e-98 329.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGB10103.1 - 2.7e-72 242.4 0.9 5.2e-72 241.5 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EGB10103.1 - 9.1e-71 238.7 0.0 1.4e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EGB10103.1 - 6.2e-46 156.2 0.0 1.3e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGB10103.1 - 1.4e-45 154.6 0.0 2.5e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_6 PF04992.14 EGB10103.1 - 2.8e-44 151.2 0.0 5.5e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.17 EGB10103.1 - 1.4e-34 118.3 0.1 3.2e-34 117.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGB10103.1 - 6.9e-22 76.6 276.2 0.0047 17.2 12.1 16.6 8 3 0 16 16 16 12 RNA polymerase Rpb1 C-terminal repeat Helicase_C PF00271.31 EGB10104.1 - 1.1e-05 25.7 0.1 4.9e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RCC1 PF00415.18 EGB10105.1 - 2.6e-32 111.2 13.7 0.00033 21.2 0.0 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB10105.1 - 1.2e-19 69.6 42.4 5e-05 23.0 3.5 7.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Guanylate_cyc PF00211.20 EGB10105.1 - 8.5e-17 61.4 0.0 3.9e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Ank_2 PF12796.7 EGB10106.1 - 4.7e-18 65.5 0.0 7.9e-11 42.4 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGB10106.1 - 2e-12 46.9 4.1 0.02 15.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGB10106.1 - 2.6e-12 46.7 4.7 8.1e-05 22.8 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10106.1 - 9.8e-12 44.0 2.2 0.038 14.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EGB10106.1 - 3.6e-06 27.4 1.1 0.0017 18.9 0.1 3.7 3 2 1 4 4 4 1 Ankyrin repeats (many copies) SAM_1 PF00536.30 EGB10107.1 - 8.2e-16 58.2 0.0 1.5e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGB10107.1 - 2.6e-14 53.1 0.0 4.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 EGB10107.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SMC_Nse1 PF07574.13 EGB10108.1 - 5.1e-09 36.3 0.0 3.6e-05 23.8 0.0 2.0 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex DUF1455 PF07306.11 EGB10109.1 - 0.065 13.2 2.2 0.11 12.5 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1455) Methyltransf_10 PF05971.12 EGB10110.1 - 2.7e-38 132.0 0.0 4.2e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase UCH PF00443.29 EGB10110.1 - 5e-36 124.5 0.0 6.6e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Gal-3-0_sulfotr PF06990.11 EGB10110.1 - 1.6e-15 56.9 2.3 1.7e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase UCH_1 PF13423.6 EGB10110.1 - 2.9e-14 53.4 0.0 4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EamA PF00892.20 EGB10110.1 - 0.00014 22.1 23.3 0.0085 16.3 7.7 2.5 2 0 0 2 2 2 2 EamA-like transporter family MTS PF05175.14 EGB10110.1 - 0.0002 21.0 0.1 0.00069 19.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB10110.1 - 0.031 15.0 0.3 0.16 12.7 0.3 2.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGB10110.1 - 0.78 9.1 3.6 1.5 8.2 3.6 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ABC_tran PF00005.27 EGB10111.1 - 1e-46 158.8 0.0 6.7e-23 81.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB10111.1 - 2.9e-15 56.9 0.2 0.0074 16.1 0.1 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB10111.1 - 8.9e-09 35.1 3.3 0.008 15.6 0.0 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 EGB10111.1 - 1.7e-07 31.2 0.7 1.2e-05 25.2 0.1 2.6 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 EGB10111.1 - 3.8e-06 27.0 0.5 0.025 14.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGB10111.1 - 2.8e-05 23.8 1.4 0.041 13.6 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EGB10111.1 - 5.2e-05 23.5 0.2 0.062 13.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EGB10111.1 - 5.8e-05 23.7 0.0 0.31 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EGB10111.1 - 9.5e-05 22.5 0.9 0.12 12.4 0.0 2.9 3 0 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EGB10111.1 - 0.00032 20.6 0.4 0.081 12.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase DLIC PF05783.11 EGB10111.1 - 0.0021 17.0 0.2 0.06 12.2 0.0 2.2 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) MeaB PF03308.16 EGB10111.1 - 0.0024 16.9 1.5 0.064 12.2 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EGB10111.1 - 0.0026 18.0 0.4 4.1 7.7 0.0 2.8 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGB10111.1 - 0.0079 16.6 6.0 0.034 14.5 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EGB10111.1 - 0.0086 15.7 1.7 0.072 12.7 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 EGB10111.1 - 0.013 15.1 0.8 2.3 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGB10111.1 - 0.013 14.6 0.8 1.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 EGB10111.1 - 0.015 15.0 3.4 1.4 8.5 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 EGB10111.1 - 0.016 15.7 0.1 3.8 8.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EGB10111.1 - 0.053 12.2 0.1 2.9 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGB10111.1 - 0.057 13.1 2.6 1.9 8.2 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGB10111.1 - 0.062 13.0 3.6 5.1 6.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 EGB10111.1 - 0.16 11.6 0.3 6.2 6.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 EGB10111.1 - 0.2 12.1 1.4 17 5.8 0.1 2.4 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 EGB10111.1 - 0.32 10.7 0.8 23 4.6 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EGB10111.1 - 0.41 10.8 7.6 0.49 10.5 0.6 3.3 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EGB10111.1 - 0.46 10.8 5.6 4.3 7.6 0.6 3.5 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGB10111.1 - 0.55 9.5 5.0 1.5 8.0 0.4 2.5 2 0 0 2 2 2 0 Zeta toxin MukB PF04310.12 EGB10111.1 - 0.6 9.9 2.4 5.1 6.8 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal NACHT PF05729.12 EGB10111.1 - 0.87 9.5 3.8 4.9 7.0 0.2 2.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EGB10111.1 - 2.1 7.5 4.7 3.7 6.7 0.1 2.4 3 0 0 3 3 2 0 NB-ARC domain ATP_bind_1 PF03029.17 EGB10111.1 - 3.4 7.4 3.9 5.9 6.6 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DnaJ_C PF01556.18 EGB10112.1 - 7.5e-32 110.5 0.1 1.1e-31 110.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB10112.1 - 4.3e-22 78.0 0.2 6.9e-22 77.3 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGB10112.1 - 0.00017 21.9 5.1 0.00043 20.6 5.1 1.6 1 0 0 1 1 1 1 DnaJ central domain Fer2_2 PF01799.20 EGB10112.1 - 0.34 11.0 4.1 0.36 10.9 2.0 2.0 1 1 1 2 2 2 0 [2Fe-2S] binding domain ThiF PF00899.21 EGB10113.1 - 3.8e-67 226.2 0.1 6.4e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EGB10113.1 - 2.2e-23 82.2 0.0 3.8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EGB10113.1 - 0.0055 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 EGB10113.1 - 0.062 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_7 PF13241.6 EGB10113.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding EF-hand_5 PF13202.6 EGB10114.1 - 2.9e-09 36.0 0.1 0.00011 21.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB10114.1 - 1.2e-08 35.2 0.1 1.6e-05 25.2 0.0 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB10114.1 - 1.5e-08 33.6 0.4 0.0054 16.2 0.0 2.5 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB10114.1 - 2.2e-07 30.2 0.0 0.0049 16.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB10114.1 - 0.015 15.1 0.5 4 7.4 0.1 2.7 1 1 1 2 2 2 0 EF-hand domain pair DUF2523 PF10734.9 EGB10114.1 - 0.02 15.4 0.4 0.092 13.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) MFS_5 PF05631.14 EGB10115.1 - 1.3e-10 40.8 3.9 8.5e-10 38.1 3.9 1.9 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGB10115.1 - 1.1e-07 31.1 31.6 1.1e-07 31.1 31.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily UDPG_MGDP_dh_N PF03721.14 EGB10116.1 - 8.4e-56 188.5 0.5 1.5e-55 187.7 0.5 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EGB10116.1 - 2.3e-30 105.1 0.5 2.3e-29 101.9 0.1 2.5 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EGB10116.1 - 3.1e-30 104.2 0.0 6.8e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain GRAM PF02893.20 EGB10117.1 - 9.5e-17 60.9 0.3 1e-16 60.8 0.3 1.0 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.6 EGB10117.1 - 0.022 15.1 0.1 0.028 14.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial PH domain DUF5106 PF17127.4 EGB10117.1 - 0.047 14.0 0.0 0.053 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Voldacs PF03517.13 EGB10117.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 EGB10117.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 ADK PF00406.22 EGB10118.1 - 2.7e-42 144.4 0.0 3.2e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGB10118.1 - 3.3e-19 69.7 0.0 5.5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EGB10118.1 - 1.5e-15 56.9 0.0 2.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGB10118.1 - 4.5e-06 27.2 0.0 8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB10118.1 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGB10118.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGB10118.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain GDP_Man_Dehyd PF16363.5 EGB10119.1 - 7.9e-154 512.0 0.0 8.9e-154 511.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGB10119.1 - 3.4e-72 242.8 0.0 4.3e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGB10119.1 - 3.7e-05 23.0 0.0 5.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGB10119.1 - 0.00011 21.4 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TAA-Trp-ring PF15401.6 EGB10119.1 - 0.074 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin NmrA PF05368.13 EGB10119.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Sulfatase PF00884.23 EGB10120.1 - 4.3e-36 124.9 0.0 5.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Bac_surface_Ag PF01103.23 EGB10121.1 - 1e-23 84.4 0.0 1.5e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Surface antigen Glyco_transf_20 PF00982.21 EGB10122.1 - 2.1e-126 422.4 0.0 2.7e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGB10122.1 - 1e-24 86.9 0.0 1.8e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Ribosomal_60s PF00428.19 EGB10123.1 - 3.5e-19 69.2 5.0 4e-19 69.0 5.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein SNF2_N PF00176.23 EGB10124.1 - 1.4e-48 165.4 0.0 7.2e-46 156.5 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB10124.1 - 3.5e-21 75.6 0.0 1.1e-19 70.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB10124.1 - 0.0023 17.9 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GspH PF12019.8 EGB10124.1 - 0.15 12.5 0.6 0.34 11.3 0.6 1.6 1 0 0 1 1 1 0 Type II transport protein GspH Sulfotransfer_3 PF13469.6 EGB10125.1 - 8.6e-30 104.7 0.0 1.8e-29 103.7 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB10125.1 - 4.1e-07 29.7 0.0 2e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain B12D PF06522.11 EGB10125.1 - 0.085 12.7 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit CSD PF00313.22 EGB10126.1 - 1.8e-13 50.1 0.1 2.5e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Chloroa_b-bind PF00504.21 EGB10127.1 - 1.3e-24 87.5 0.1 1.7e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4515 PF14988.6 EGB10128.1 - 0.0022 17.8 28.9 0.0022 17.8 28.9 2.6 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) GP41 PF00517.17 EGB10128.1 - 3.5 7.5 6.5 6.6 6.6 0.9 3.2 1 1 1 3 3 3 0 Retroviral envelope protein Bax1-I PF01027.20 EGB10129.1 - 0.0058 16.5 3.1 2.7 7.8 0.0 3.2 1 1 2 3 3 3 2 Inhibitor of apoptosis-promoting Bax1 Kinesin PF00225.23 EGB10130.1 - 4.6e-81 272.3 0.0 6.8e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB10130.1 - 6.6e-13 48.8 0.0 1.8e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Multi_Drug_Res PF00893.19 EGB10130.1 - 0.029 15.0 0.4 0.053 14.2 0.4 1.3 1 0 0 1 1 1 0 Small Multidrug Resistance protein PKcGMP_CC PF16808.5 EGB10130.1 - 0.067 13.1 0.1 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sulfatase PF00884.23 EGB10131.1 - 3.3e-62 210.6 0.3 5.1e-62 210.0 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB10131.1 - 5.2e-06 26.3 0.1 1.1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EGB10131.1 - 0.0028 18.4 0.1 0.0055 17.4 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Patched PF02460.18 EGB10132.1 - 2.2e-23 82.3 11.2 3e-14 52.1 0.8 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EGB10132.1 - 4.5e-15 55.8 16.4 4.2e-12 46.2 2.6 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation PhoD PF09423.10 EGB10132.1 - 2.3e-11 43.3 0.0 1e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase MMPL PF03176.15 EGB10132.1 - 6.6e-09 35.1 11.6 6.6e-09 35.1 11.6 4.3 3 2 0 3 3 3 2 MMPL family Pro_isomerase PF00160.21 EGB10133.1 - 1.4e-44 152.1 0.1 1.6e-44 152.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_11 PF08241.12 EGB10134.1 - 1.9e-16 60.5 0.0 2.4e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB10134.1 - 4.6e-13 49.7 0.0 6.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB10134.1 - 1.2e-10 41.4 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10134.1 - 1e-08 35.8 0.0 1.4e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB10134.1 - 7.4e-05 22.6 0.0 9.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB10134.1 - 0.00065 19.1 0.0 0.00077 18.8 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGB10134.1 - 0.00069 19.0 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EGB10134.1 - 0.022 13.4 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Lectin_leg-like PF03388.13 EGB10134.1 - 0.067 12.5 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Legume-like lectin family S-AdoMet_synt_C PF02773.16 EGB10135.1 - 1e-62 210.2 0.0 1.5e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGB10135.1 - 4.6e-45 152.7 0.0 7.6e-45 152.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGB10135.1 - 5.3e-40 136.1 0.0 9.1e-40 135.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Pro_isomerase PF00160.21 EGB10136.1 - 2.9e-42 144.6 0.0 3.2e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FBPase PF00316.20 EGB10137.1 - 1e-60 204.5 0.4 1.9e-60 203.6 0.2 1.5 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain HflK_N PF12221.8 EGB10138.1 - 0.11 12.5 1.8 0.41 10.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Pkinase PF00069.25 EGB10140.1 - 3.8e-22 78.9 0.0 4.3e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10140.1 - 1.3e-12 47.6 0.0 1.4e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB10140.1 - 0.088 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGB10140.1 - 0.3 10.1 0.0 0.35 9.9 0.0 1.2 1 1 0 1 1 1 0 Seadornavirus VP7 Arf PF00025.21 EGB10141.1 - 2e-55 186.9 0.3 1.9e-44 151.2 0.3 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGB10141.1 - 2.1e-11 44.1 0.0 3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGB10141.1 - 4.4e-09 36.0 1.9 0.00095 18.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGB10141.1 - 2.9e-07 30.2 0.0 4.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGB10141.1 - 9.6e-07 28.4 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB10141.1 - 7.5e-06 26.0 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB10141.1 - 2.4e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EGB10141.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 EGB10141.1 - 0.048 13.4 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGB10141.1 - 0.17 12.1 0.0 0.74 10.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain DP PF08781.10 EGB10143.1 - 1.6e-22 79.9 0.0 3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 EGB10143.1 - 8.3e-21 73.8 0.3 5.8e-20 71.1 0.3 2.2 1 1 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain tRNA-synt_1 PF00133.22 EGB10144.1 - 1.1e-177 592.0 0.0 1.3e-177 591.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGB10144.1 - 5.9e-24 84.8 0.0 1.2e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGB10144.1 - 4.1e-20 71.9 0.0 2.6e-10 39.6 0.0 4.1 4 0 0 4 4 4 4 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 EGB10144.1 - 0.00014 21.6 1.2 0.00029 20.6 1.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 EGB10144.1 - 0.0022 17.4 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DUF2735 PF10931.8 EGB10144.1 - 0.088 13.5 0.4 0.27 11.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) tRNA-synt_1f PF01921.18 EGB10144.1 - 0.23 10.3 0.0 0.95 8.3 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF2252 PF10009.9 EGB10145.1 - 1.6e-65 221.7 1.7 2.2e-65 221.3 1.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) tRNA-synt_1d PF00750.19 EGB10146.1 - 3.2e-107 358.5 0.0 4.4e-107 358.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGB10146.1 - 2.4e-26 92.3 0.0 4.3e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGB10146.1 - 2e-15 57.2 0.0 5.8e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 EGB10146.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGB10146.1 - 0.18 10.5 0.1 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Syja_N PF02383.18 EGB10147.1 - 7.3e-69 232.5 0.0 9.3e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain ESX-1_EspG PF14011.6 EGB10147.1 - 0.013 15.1 1.6 0.036 13.7 1.1 1.9 1 1 1 2 2 2 0 EspG family zf-CCCH PF00642.24 EGB10148.1 - 8.9e-11 41.4 14.5 1.8e-06 27.7 4.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGB10148.1 - 0.00036 21.2 3.1 0.14 12.9 0.8 2.4 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 EGB10148.1 - 0.0041 16.9 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGB10148.1 - 0.0045 17.0 2.3 0.0045 17.0 2.3 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 EGB10148.1 - 0.01 16.1 2.8 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 EGB10148.1 - 1.7 8.5 12.9 0.2 11.5 2.7 2.7 2 0 0 2 2 2 0 CCCH-type zinc finger Tachystatin_B PF11478.8 EGB10148.1 - 6.9 6.7 10.2 0.09 12.7 1.9 2.1 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B E2F_TDP PF02319.20 EGB10149.1 - 7.1e-22 77.3 0.0 1.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 EGB10149.1 - 1.8e-13 50.6 0.0 3.7e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain DUF2250 PF10007.9 EGB10149.1 - 0.0076 16.3 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.19 EGB10149.1 - 0.0091 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 EGB10149.1 - 0.043 14.0 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC TPR_1 PF00515.28 EGB10150.1 - 5.9e-14 51.2 2.0 2.3e-05 24.0 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10150.1 - 7.5e-10 38.2 2.8 0.0048 16.9 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10150.1 - 1.6e-08 34.1 0.2 0.027 14.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB10150.1 - 7.3e-05 22.8 1.5 0.041 14.0 0.9 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10150.1 - 0.00029 21.1 4.9 0.11 12.8 3.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB10150.1 - 0.00045 20.0 1.0 0.048 13.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB10150.1 - 0.0025 18.1 1.1 3.1 8.4 0.4 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB10150.1 - 0.0029 17.3 0.4 0.011 15.5 0.2 2.1 2 1 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 EGB10150.1 - 0.0036 17.8 0.5 0.0072 16.8 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGB10150.1 - 0.0046 16.8 1.3 0.15 12.0 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB10150.1 - 0.013 15.6 0.2 0.23 11.6 0.2 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EGB10150.1 - 0.071 14.0 3.3 10 7.3 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB10150.1 - 0.076 13.7 0.6 34 5.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB10150.1 - 0.22 12.2 6.5 15 6.3 4.5 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Ubiquitin_2 PF14560.6 EGB10151.1 - 2.2e-24 85.7 0.0 3e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 EGB10151.1 - 6.1e-21 74.2 0.6 1e-20 73.5 0.2 1.6 2 0 0 2 2 2 1 CAP-Gly domain ubiquitin PF00240.23 EGB10151.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 EGB10152.1 - 4.8e-63 213.0 0.0 6.5e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10152.1 - 3.8e-27 95.2 0.0 5.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGB10152.1 - 2.5e-18 64.2 9.0 6.8e-08 31.5 0.5 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EGB10152.1 - 2.6e-17 63.0 2.6 2.3e-09 37.6 0.3 3.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB10152.1 - 6.6e-17 59.9 5.0 2.5e-05 23.9 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 EGB10152.1 - 3.3e-15 54.8 2.7 7.2e-07 28.4 0.8 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGB10152.1 - 3.3e-10 39.7 1.2 6.4e-06 25.9 0.6 2.8 2 0 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.6 EGB10152.1 - 2.3e-05 23.9 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB10152.1 - 0.0014 18.6 0.1 0.0047 16.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB10152.1 - 0.0025 16.7 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB10152.1 - 0.0029 17.0 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 EGB10152.1 - 0.0082 16.5 0.9 5.1 7.5 0.0 3.4 2 1 0 2 2 2 1 EF-hand domain YrbL-PhoP_reg PF10707.9 EGB10152.1 - 0.04 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EGB10152.1 - 0.046 13.3 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EGB10152.1 - 0.053 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_4 PF12763.7 EGB10152.1 - 0.064 13.2 2.2 1.4 8.9 0.1 3.1 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF3523 PF12037.8 EGB10153.1 - 3.6e-33 115.1 25.8 4.8e-33 114.7 25.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 EGB10153.1 - 1.8e-23 83.4 0.0 3.7e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGB10153.1 - 3.4e-06 26.9 0.0 1.3e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB10153.1 - 4.9e-06 26.9 0.0 0.0021 18.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB10153.1 - 3.5e-05 24.3 0.2 3.5e-05 24.3 0.2 4.6 2 2 0 2 2 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EGB10153.1 - 0.00033 20.1 0.3 0.0013 18.2 0.1 2.1 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB10153.1 - 0.00035 20.6 4.2 0.00077 19.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGB10153.1 - 0.0011 19.1 0.0 0.0011 19.1 0.0 3.3 2 1 1 3 3 2 1 AAA domain AAA_3 PF07726.11 EGB10153.1 - 0.004 17.0 0.0 0.0094 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGB10153.1 - 0.029 14.3 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_lid_3 PF17862.1 EGB10153.1 - 0.029 14.2 0.1 0.029 14.2 0.1 3.0 3 0 0 3 3 2 0 AAA+ lid domain Sigma54_activat PF00158.26 EGB10153.1 - 0.036 13.8 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EGB10153.1 - 0.038 14.5 0.0 0.038 14.5 0.0 2.8 2 1 0 2 2 1 0 AAA domain Zot PF05707.12 EGB10153.1 - 0.045 13.4 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EGB10153.1 - 0.075 12.8 0.0 0.075 12.8 0.0 3.1 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EGB10153.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EGB10153.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EGB10153.1 - 0.14 12.5 1.8 0.39 11.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EGB10153.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EGB10153.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGB10153.1 - 0.26 11.7 0.2 0.26 11.7 0.2 3.0 2 1 1 3 3 3 0 AAA domain WD40 PF00400.32 EGB10154.1 - 1.2e-19 70.3 14.7 0.00057 20.6 1.5 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB10154.1 - 8e-06 26.1 0.0 0.00025 21.3 0.0 3.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB10154.1 - 0.0014 17.7 0.1 0.0096 14.9 0.0 1.9 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BUD22 PF09073.10 EGB10154.1 - 0.45 9.8 5.0 0.62 9.3 5.0 1.1 1 0 0 1 1 1 0 BUD22 Cnd2 PF05786.14 EGB10154.1 - 1 7.9 6.4 1.4 7.5 6.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 EGF_alliinase PF04863.13 EGB10154.1 - 1 9.8 9.2 3.6 8.1 0.6 3.9 3 0 0 3 3 3 0 Alliinase EGF-like domain FAM176 PF14851.6 EGB10154.1 - 2.1 8.0 5.6 3.4 7.3 5.6 1.2 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 EGB10154.1 - 3.4 6.7 17.8 4.9 6.2 17.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sugar_tr PF00083.24 EGB10155.1 - 1.2e-92 311.1 12.1 1.5e-92 310.8 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB10155.1 - 1.8e-27 96.2 28.8 1.8e-27 96.2 28.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily SEEEED PF14797.6 EGB10155.1 - 0.0015 18.7 12.1 0.0025 18.0 12.1 1.3 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex SAP PF02037.27 EGB10155.1 - 0.0023 17.7 0.2 0.0046 16.7 0.2 1.5 1 0 0 1 1 1 1 SAP domain Uds1 PF15456.6 EGB10155.1 - 8.2 6.6 7.1 88 3.3 7.1 2.2 1 1 0 1 1 1 0 Up-regulated During Septation Acetyltransf_10 PF13673.7 EGB10156.1 - 2.7e-12 46.7 0.0 2.7e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGB10156.1 - 2.1e-11 44.1 0.3 4.2e-11 43.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGB10156.1 - 1.5e-09 38.2 0.4 1e-08 35.4 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EGB10156.1 - 2.6e-05 24.0 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 EGB10156.1 - 0.0019 18.1 0.0 0.0056 16.6 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGB10156.1 - 0.061 13.5 0.2 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Ion_trans PF00520.31 EGB10157.1 - 1.3e-13 50.7 7.2 1.9e-13 50.2 7.2 1.2 1 0 0 1 1 1 1 Ion transport protein Pro_racemase PF05544.11 EGB10158.1 - 7.6e-88 294.7 0.1 9.1e-88 294.4 0.1 1.1 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 EGB10158.1 - 0.0082 15.6 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein Ald_Xan_dh_C2 PF02738.18 EGB10159.1 - 9.6e-165 549.1 1.2 1.4e-164 548.6 1.2 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EGB10159.1 - 6.8e-39 133.3 0.0 3e-38 131.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 EGB10159.1 - 2.3e-26 91.6 0.2 8.1e-26 89.9 0.2 2.1 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 EGB10159.1 - 6.9e-24 84.0 1.3 1.7e-23 82.7 0.4 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EGB10159.1 - 2.3e-17 63.3 5.6 7.5e-17 61.7 2.6 2.6 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 EGB10159.1 - 4.8e-07 29.7 1.8 4.8e-07 29.7 1.8 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF4694 PF15765.5 EGB10160.1 - 6.3 6.8 6.2 1.4 8.9 0.1 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4694) Peptidase_M16 PF00675.20 EGB10161.1 - 6.4e-36 123.6 0.0 7.8e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_S10 PF00450.22 EGB10163.1 - 4.3e-80 270.2 0.0 5e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ECH_1 PF00378.20 EGB10164.1 - 6.9e-31 107.4 0.0 8.1e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB10164.1 - 7.2e-22 78.3 0.0 8.1e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AP2 PF00847.20 EGB10165.1 - 6.2e-07 29.6 0.4 1.2e-06 28.7 0.4 1.4 1 0 0 1 1 1 1 AP2 domain Afi1 PF07792.12 EGB10165.1 - 0.0065 16.9 0.0 0.015 15.8 0.0 1.5 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Robl_LC7 PF03259.17 EGB10166.1 - 1.1e-17 63.5 0.0 1.3e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGB10166.1 - 0.037 14.0 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 SNARE_assoc PF09335.11 EGB10167.1 - 1e-12 48.6 10.2 3.9e-10 40.2 1.7 2.8 2 0 0 2 2 2 2 SNARE associated Golgi protein Exostosin PF03016.15 EGB10167.1 - 2.3e-10 40.2 0.0 4.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Glyco_transf_10 PF00852.19 EGB10167.1 - 1.7e-08 34.4 0.0 1.4e-07 31.4 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term LRR_8 PF13855.6 EGB10167.1 - 6.6e-07 29.0 3.2 1.9e-06 27.5 2.7 1.9 1 1 1 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EGB10167.1 - 1.7e-06 28.2 0.1 0.0062 16.9 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB10167.1 - 0.00059 19.4 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat Methyltransf_21 PF05050.12 EGB10167.1 - 0.0019 18.2 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain LRR_6 PF13516.6 EGB10167.1 - 0.0025 17.7 4.7 0.23 11.6 0.5 4.2 4 0 0 4 4 4 1 Leucine Rich repeat Aldo_ket_red PF00248.21 EGB10168.1 - 1.9e-43 148.7 0.0 2.2e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tyrosinase PF00264.20 EGB10169.1 - 2.2e-10 41.2 0.2 1.9e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Common central domain of tyrosinase LSM PF01423.22 EGB10171.1 - 4.2e-15 55.2 0.5 6.1e-15 54.7 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGB10171.1 - 0.021 15.0 0.2 0.048 13.8 0.1 1.8 2 1 0 2 2 2 0 Ataxin 2 SM domain Asp PF00026.23 EGB10172.1 - 6.3e-91 305.1 0.4 7.3e-91 304.9 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGB10172.1 - 6.3e-11 42.8 0.2 2.3e-07 31.2 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGB10172.1 - 0.046 13.5 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal AFP_2 PF18815.1 EGB10172.1 - 0.064 13.5 0.8 1.8 8.9 0.1 2.8 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat Glyco_hydro_39 PF01229.17 EGB10173.1 - 1.6e-61 208.4 0.0 1.4e-60 205.4 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 Cellulase PF00150.18 EGB10174.1 - 1.8e-26 93.2 0.0 2.9e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EGB10174.1 - 0.00042 19.8 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 EGB10174.1 - 0.0095 15.6 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 FKBP_C PF00254.28 EGB10175.1 - 7.1e-22 77.5 0.0 9.2e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AAA_12 PF13087.6 EGB10178.1 - 8.1e-32 110.5 0.0 1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGB10178.1 - 7.5e-28 98.0 0.1 2e-15 57.3 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EGB10178.1 - 1.7e-14 54.0 1.2 3.1e-14 53.1 0.3 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGB10178.1 - 1.7e-10 41.4 0.0 6.6e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB10178.1 - 0.00025 20.8 0.6 0.0011 18.8 0.6 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EGB10178.1 - 0.00074 19.9 0.8 0.0042 17.5 0.5 2.4 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGB10178.1 - 0.0017 18.2 0.1 0.0058 16.4 0.0 1.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGB10178.1 - 0.003 17.8 0.0 0.01 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EGB10178.1 - 0.0035 16.8 0.0 0.6 9.5 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 EGB10178.1 - 0.016 14.8 0.0 0.4 10.2 0.0 2.1 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EGB10178.1 - 0.024 14.5 0.3 0.085 12.7 0.3 2.0 1 1 0 1 1 1 0 Helicase Acetyltransf_1 PF00583.25 EGB10178.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PreAtp-grasp PF18604.1 EGB10178.1 - 0.065 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Pre ATP-grasp domain AAA PF00004.29 EGB10178.1 - 0.097 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pentapeptide PF00805.22 EGB10179.1 - 2.4e-12 46.2 6.6 3.3e-08 33.0 0.3 2.9 2 1 0 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EGB10179.1 - 3.9e-09 36.5 2.2 1.9e-08 34.4 0.9 1.9 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGB10179.1 - 2e-05 24.7 2.1 0.0018 18.4 1.0 2.7 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) PfkB PF00294.24 EGB10180.1 - 8.8e-63 212.4 3.3 1.2e-62 212.0 3.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase zf-C3HC4_2 PF13923.6 EGB10181.1 - 1.6e-07 31.1 7.8 1.9e-07 30.8 7.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB10181.1 - 7.7e-07 28.9 9.6 9.9e-07 28.5 9.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGB10181.1 - 1.1e-05 25.2 8.9 1.2e-05 25.0 8.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB10181.1 - 3.6e-05 24.0 8.5 4.8e-05 23.6 8.5 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGB10181.1 - 0.00014 21.8 8.5 0.00017 21.5 8.5 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_5 PF17121.5 EGB10181.1 - 0.00029 20.7 4.6 0.00042 20.1 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB10181.1 - 0.0012 19.1 6.6 0.0015 18.7 6.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGB10181.1 - 0.0015 18.3 2.1 0.0018 18.1 2.1 1.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGB10181.1 - 0.0025 17.6 6.7 0.0033 17.2 6.7 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EGB10181.1 - 0.0051 16.8 6.8 0.0078 16.2 6.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGB10181.1 - 0.024 14.5 7.0 0.03 14.2 7.0 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGB10181.1 - 0.1 12.8 7.6 0.16 12.1 7.6 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Indigoidine_A PF04227.12 EGB10182.1 - 1.3e-114 382.5 6.1 1.5e-114 382.3 6.1 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein DAGAT PF03982.13 EGB10183.1 - 4.9e-26 91.3 0.0 5.6e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase N2227 PF07942.12 EGB10184.1 - 5.8e-81 271.7 0.0 6.5e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Chloroa_b-bind PF00504.21 EGB10185.1 - 4.3e-26 92.4 0.0 6.8e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Sel1 PF08238.12 EGB10186.1 - 7.7e-18 64.5 2.8 5e-05 23.8 0.0 5.2 4 0 0 4 4 4 4 Sel1 repeat ABC_tran PF00005.27 EGB10186.1 - 8.6e-08 32.8 0.0 3.9e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter zf-MYND PF01753.18 EGB10186.1 - 1.1e-05 25.4 21.5 2.2e-05 24.5 10.9 3.8 3 0 0 3 3 3 1 MYND finger SbcCD_C PF13558.6 EGB10186.1 - 0.0005 20.2 0.0 0.0052 17.0 0.0 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EGB10186.1 - 0.023 14.9 0.7 4.2 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ecl1 PF12855.7 EGB10186.1 - 1.7 9.7 5.5 3.5 8.7 5.5 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF1995 PF09353.10 EGB10187.1 - 7.1e-05 22.9 0.2 0.00012 22.2 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) Pec_lyase_C PF00544.19 EGB10188.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Pectate lyase Mito_carr PF00153.27 EGB10189.1 - 5e-27 93.7 1.2 1.3e-13 50.7 0.0 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein Acatn PF13000.7 EGB10190.1 - 2.3e-94 316.9 0.0 3.3e-76 256.9 0.0 3.1 2 1 1 3 3 3 3 Acetyl-coenzyme A transporter 1 Polysacc_deac_1 PF01522.21 EGB10190.1 - 6.5e-12 45.4 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase BT1 PF03092.16 EGB10190.1 - 0.12 10.6 1.1 0.2 9.8 1.1 1.4 1 0 0 1 1 1 0 BT1 family Peptidase_M14 PF00246.24 EGB10191.1 - 7.3e-15 55.5 0.0 1.3e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EGB10191.1 - 2.5e-11 43.9 0.2 5.1e-11 42.9 0.2 1.6 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EGB10191.1 - 6.4e-05 22.2 0.0 9.4e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF5486 PF17588.2 EGB10191.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5486) AFG1_ATPase PF03969.16 EGB10192.1 - 5.8e-84 282.1 0.2 7.2e-82 275.2 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase EF-hand_6 PF13405.6 EGB10192.1 - 7.9e-06 25.4 0.1 3.2e-05 23.5 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EGB10192.1 - 8.6e-06 26.1 0.1 4e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB10192.1 - 1.8e-05 24.0 0.1 4.9e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EGB10192.1 - 2.2e-05 23.7 0.3 6e-05 22.3 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EGB10192.1 - 0.00089 19.1 0.0 0.0053 16.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.6 EGB10192.1 - 0.085 13.1 0.0 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain HECT PF00632.25 EGB10193.1 - 1.5e-51 175.7 0.0 1.8e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Tubulin PF00091.25 EGB10194.1 - 3.6e-63 213.3 0.0 5e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB10194.1 - 2.4e-49 166.7 0.0 3.5e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Peptidase_S8 PF00082.22 EGB10195.1 - 3.2e-60 203.9 0.4 3.2e-60 203.9 0.4 1.8 2 0 0 2 2 2 1 Subtilase family Sulfatase PF00884.23 EGB10195.1 - 1.5e-46 159.2 0.0 2.5e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Sulfatase TPPII PF12580.8 EGB10195.1 - 1e-22 80.5 0.0 4.5e-22 78.4 0.0 1.9 1 1 0 1 1 1 1 Tripeptidyl peptidase II Sulfatase_C PF14707.6 EGB10195.1 - 0.002 18.8 0.1 0.0048 17.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 EGB10195.1 - 0.019 14.5 0.1 0.071 12.7 0.1 1.8 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sec1 PF00995.23 EGB10196.1 - 3.3e-94 317.2 0.0 3.7e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TACC_C PF05010.14 EGB10196.1 - 0.0032 17.3 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal EF-hand_5 PF13202.6 EGB10197.1 - 4.2e-13 48.1 3.6 1.8e-06 27.2 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 EGB10197.1 - 1e-11 43.5 2.7 2.6e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB10197.1 - 2.5e-11 43.9 0.1 2.8e-11 43.7 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB10197.1 - 3e-11 43.0 0.5 3e-11 43.0 0.5 1.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB10197.1 - 6e-11 41.4 0.5 2.5e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain PIP5K PF01504.18 EGB10198.1 - 1.9e-27 96.2 4.3 3.4e-27 95.4 4.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF3040 PF11239.8 EGB10199.1 - 0.34 11.2 2.3 0.59 10.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Peptidase_S10 PF00450.22 EGB10200.1 - 2.2e-87 294.2 0.0 2.7e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_trans_1_4 PF13692.6 EGB10201.1 - 2.6e-08 34.4 0.0 4.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB10201.1 - 0.00013 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 adh_short PF00106.25 EGB10202.1 - 1.5e-25 89.8 0.7 2.5e-25 89.1 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB10202.1 - 3e-21 76.1 1.6 4.1e-21 75.6 1.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB10202.1 - 0.0048 16.8 1.7 0.0049 16.8 0.4 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EGB10202.1 - 0.039 13.4 0.3 0.083 12.3 0.3 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Metallophos PF00149.28 EGB10203.1 - 1.2e-07 32.5 0.0 1.2e-07 32.4 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Chloroa_b-bind PF00504.21 EGB10204.1 - 1.1e-23 84.5 0.0 1.5e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TPR_1 PF00515.28 EGB10205.1 - 6.8e-18 63.7 8.4 1.3e-05 24.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10205.1 - 1e-13 50.2 6.5 0.007 16.4 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB10205.1 - 3.1e-09 36.9 6.2 0.37 11.7 0.0 6.8 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB10205.1 - 3e-08 33.5 0.2 0.18 12.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB10205.1 - 1.6e-07 30.9 4.4 0.036 14.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10205.1 - 3.6e-06 27.2 6.6 0.029 14.6 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10205.1 - 5.2e-06 26.3 1.2 2 8.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB10205.1 - 0.00038 20.9 5.0 1.5 9.3 0.0 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB10205.1 - 0.0011 19.0 0.0 0.078 13.1 0.0 3.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EGB10205.1 - 0.0022 18.1 2.0 1.2 9.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 EGB10205.1 - 0.0033 17.5 0.5 15 5.7 0.1 3.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.9 EGB10205.1 - 0.0086 16.1 0.1 0.94 9.6 0.0 2.6 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_11 PF13414.6 EGB10205.1 - 0.011 15.4 5.7 2.1 8.1 0.0 5.0 4 3 1 5 5 5 0 TPR repeat TPR_20 PF14561.6 EGB10205.1 - 0.032 14.6 1.3 7.9 6.9 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB10205.1 - 0.043 14.5 19.0 0.94 10.2 0.0 5.3 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB10205.1 - 0.13 12.9 3.9 17 6.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGB10205.1 - 0.6 10.2 4.8 14 5.8 0.0 3.7 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EGB10205.1 - 0.98 9.4 4.2 11 6.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Strumpellin PF10266.9 EGB10206.1 - 0 1357.0 0.0 0 1356.8 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Glyco_tranf_2_3 PF13641.6 EGB10207.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EGB10207.1 - 0.053 14.0 0.7 0.23 12.0 0.2 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 WW PF00397.26 EGB10208.1 - 1.5e-36 124.2 32.3 5e-06 26.5 0.0 8.9 8 0 0 8 8 8 6 WW domain zf-RanBP PF00641.18 EGB10208.1 - 0.0012 18.1 2.9 0.0032 16.7 2.9 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 EGB10208.1 - 0.87 9.4 2.9 3.4 7.5 2.9 2.1 1 0 0 1 1 1 0 zinc-ribbon domain FAD_binding_3 PF01494.19 EGB10209.1 - 6.1e-11 42.2 8.2 3.3e-06 26.6 1.5 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EGB10209.1 - 3.4e-05 24.0 0.1 0.0001 22.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGB10209.1 - 0.024 14.0 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EGB10209.1 - 0.032 13.5 0.0 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGB10209.1 - 0.086 11.9 0.1 0.17 10.9 0.1 1.4 2 0 0 2 2 2 0 Squalene epoxidase AAA_12 PF13087.6 EGB10210.1 - 4.4e-50 170.1 0.0 5.1e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGB10210.1 - 0.0065 16.2 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EGB10210.1 - 0.012 15.5 0.3 0.023 14.5 0.3 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Thioredoxin PF00085.20 EGB10211.1 - 9.7e-18 64.1 0.1 1e-17 64.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB10211.1 - 1.7e-05 25.2 0.0 0.00027 21.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EGB10211.1 - 0.0024 17.6 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGB10211.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 EGB10211.1 - 0.015 15.2 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EGB10211.1 - 0.018 15.4 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 EGB10211.1 - 0.069 13.1 0.0 0.086 12.8 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Cse1 PF08506.10 EGB10212.1 - 2.7e-117 391.7 0.0 3.5e-117 391.3 0.0 1.1 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EGB10212.1 - 3e-101 339.1 0.0 4.3e-101 338.6 0.0 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EGB10212.1 - 6.7e-06 25.9 0.0 2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGB10212.1 - 0.0067 16.5 0.1 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 Exportin 1-like protein WD40 PF00400.32 EGB10213.1 - 4.8e-17 62.0 9.3 0.00043 21.0 0.0 6.0 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB10213.1 - 2.3e-07 31.0 0.0 0.99 9.7 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1771 PF08590.10 EGB10214.1 - 5.6e-12 45.9 10.2 5.6e-12 45.9 10.2 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGB10214.1 - 1.1e-07 32.0 0.3 2.2e-07 31.1 0.3 1.6 1 0 0 1 1 1 1 Smr domain IMD PF08397.11 EGB10214.1 - 0.084 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain SpoU_methylase PF00588.19 EGB10215.1 - 4.7e-26 91.6 0.0 5.4e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family TRIC PF05197.13 EGB10216.1 - 0.0059 16.2 0.1 0.0089 15.6 0.1 1.2 1 0 0 1 1 1 1 TRIC channel Sulfatase PF00884.23 EGB10218.1 - 1.1e-21 77.5 0.0 1.2e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB10218.1 - 0.00077 19.1 0.1 0.00093 18.9 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Spike_NTD PF16451.5 EGB10218.1 - 0.11 11.8 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain Metalloenzyme PF01676.18 EGB10218.1 - 0.21 10.9 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Metalloenzyme superfamily Ank_2 PF12796.7 EGB10219.1 - 3.1e-12 46.9 0.0 0.00014 22.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) zf-MYND PF01753.18 EGB10219.1 - 6e-09 35.9 13.0 1.5e-08 34.6 13.0 1.7 1 0 0 1 1 1 1 MYND finger Ank PF00023.30 EGB10219.1 - 5.1e-08 33.0 2.5 0.22 12.1 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGB10219.1 - 1.1e-07 31.6 0.3 0.12 13.0 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EGB10219.1 - 1.2e-07 32.2 0.2 9e-05 22.9 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) UvrD_C_2 PF13538.6 EGB10219.1 - 6.8e-05 22.6 0.6 0.03 14.1 0.1 3.4 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 EGB10219.1 - 0.0004 19.9 0.0 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Ank_5 PF13857.6 EGB10219.1 - 0.00051 20.3 0.5 0.03 14.6 0.0 3.7 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Sigma54_activat PF00158.26 EGB10219.1 - 0.048 13.4 0.0 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGB10219.1 - 0.072 13.4 9.3 0.24 11.7 0.1 4.0 4 0 0 4 4 4 0 AAA domain Atg14 PF10186.9 EGB10219.1 - 0.36 9.9 7.1 0.67 9.0 7.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C6H2 PF15801.5 EGB10219.1 - 1.1 9.6 15.8 0.059 13.7 10.4 1.8 2 0 0 2 2 1 0 zf-MYND-like zinc finger, mRNA-binding Spc7 PF08317.11 EGB10219.1 - 8.9 5.1 12.7 21 3.9 12.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Ank_4 PF13637.6 EGB10220.1 - 1.2e-18 67.3 0.6 2.8e-12 46.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB10220.1 - 3.8e-16 59.4 0.0 1.1e-10 41.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB10220.1 - 5.5e-15 54.0 0.1 0.00084 19.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB10220.1 - 1.3e-14 54.1 3.3 2.8e-05 24.3 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB10220.1 - 1.7e-13 50.3 0.4 0.0069 16.8 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Glyco_hydro_45 PF02015.16 EGB10221.1 - 1.2e-44 152.8 13.8 1.3e-44 152.6 13.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DPBB_1 PF03330.18 EGB10221.1 - 0.045 14.0 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Lytic transglycolase Mersacidin PF16934.5 EGB10222.1 - 0.01 15.6 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) OmpH PF03938.14 EGB10222.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PsbI PF02532.14 EGB10222.1 - 0.17 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Abhydrolase_5 PF12695.7 EGB10223.1 - 1.7e-05 24.7 0.2 1.7e-05 24.7 0.2 1.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family CAAX_1 PF15895.5 EGB10223.1 - 0.058 13.3 1.9 0.065 13.1 1.9 1.1 1 0 0 1 1 1 0 CAAX box cerebral protein 1 Form_Nir_trans PF01226.17 EGB10224.1 - 1.8e-68 230.4 27.4 2.1e-68 230.2 27.4 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter zf-rbx1 PF12678.7 EGB10225.1 - 1.3e-17 63.8 4.4 1.3e-17 63.8 4.4 1.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGB10225.1 - 3.6e-10 39.8 9.3 5.9e-10 39.1 9.3 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGB10225.1 - 7.8e-08 32.5 7.4 1.1e-06 28.9 7.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB10225.1 - 2.3e-05 24.2 6.9 0.0012 18.7 3.7 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB10225.1 - 0.0011 18.8 3.8 0.0074 16.1 3.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.11 EGB10225.1 - 0.0091 16.0 1.8 0.22 11.5 1.8 2.1 1 1 0 1 1 1 1 Baculovirus U-box/Ring-like domain zf-RING_5 PF14634.6 EGB10225.1 - 0.02 14.8 3.7 0.1 12.6 3.7 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB10225.1 - 0.029 14.4 5.0 0.13 12.4 3.4 2.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGB10225.1 - 0.16 11.9 11.6 0.33 10.8 3.9 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB10225.1 - 0.32 10.9 11.8 0.44 10.4 3.7 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EGB10225.1 - 1.3 9.2 11.5 16 5.7 11.5 2.4 1 1 0 1 1 1 0 RING-variant domain MarR_2 PF12802.7 EGB10226.1 - 0.8 9.6 13.1 2.3 8.2 0.3 5.1 5 0 0 5 5 5 0 MarR family SLAC1 PF03595.17 EGB10227.1 - 2.5e-13 50.0 13.9 1.5e-07 31.0 9.1 3.3 4 0 0 4 4 4 2 Voltage-dependent anion channel polyprenyl_synt PF00348.17 EGB10228.1 - 1.9e-27 96.0 0.1 3.2e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Mitoc_mL59 PF18126.1 EGB10228.1 - 5.6e-06 26.7 0.6 5.6e-06 26.7 0.6 3.5 2 2 0 2 2 2 1 Mitochondrial ribosomal protein mL59 XPG_I PF00867.18 EGB10229.1 - 1.5e-26 92.6 0.0 2.5e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGB10229.1 - 1.3e-23 83.4 0.0 2.8e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.16 EGB10229.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EGB10229.1 - 0.0021 18.6 0.0 0.0057 17.2 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF3701 PF12482.8 EGB10229.1 - 0.019 15.0 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 Phage integrase protein HHH PF00633.23 EGB10229.1 - 0.037 13.9 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EGB10229.1 - 0.093 13.3 0.0 0.31 11.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ribosomal_L13 PF00572.18 EGB10230.1 - 3e-11 43.7 0.1 1.7e-09 38.0 0.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L13 DUF4859 PF16151.5 EGB10230.1 - 0.084 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) Kinesin PF00225.23 EGB10231.1 - 1.2e-107 359.8 0.1 1.4e-107 359.5 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB10231.1 - 6.5e-28 97.6 0.0 2.1e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding DUF695 PF05117.12 EGB10231.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF695) DUF281 PF03436.13 EGB10231.1 - 2.4 8.6 5.0 0.8 10.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Glyco_trans_1_4 PF13692.6 EGB10232.1 - 8.2e-11 42.5 1.8 2.6e-10 40.8 0.5 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB10232.1 - 1.1e-07 31.5 0.0 3.2e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGB10232.1 - 1.6e-06 28.2 5.3 3.7e-06 27.1 5.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EGB10232.1 - 0.0065 16.8 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 RCC1 PF00415.18 EGB10233.1 - 1.8e-44 150.1 19.9 7e-15 55.4 0.8 4.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB10233.1 - 1e-20 72.9 22.3 3e-11 42.8 0.4 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat SHMT PF00464.19 EGB10234.1 - 1.1e-171 570.8 0.0 1.3e-171 570.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EGB10234.1 - 5.9e-06 25.8 0.0 9.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF664 PF04978.12 EGB10235.1 - 0.52 10.7 5.9 1.7 9.0 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF664) ECH_2 PF16113.5 EGB10236.1 - 5.3e-44 151.1 2.3 5.7e-44 151.0 2.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGB10236.1 - 3.1e-11 43.0 2.1 3.4e-11 42.9 2.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NTPase_I-T PF01931.18 EGB10237.1 - 3.5e-37 127.7 0.1 3.9e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF92 PF01940.16 EGB10238.1 - 1.2e-65 221.2 11.9 1.5e-65 221.0 11.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 SLATT_1 PF18181.1 EGB10238.1 - 1.9 8.4 0.0 1.9 8.4 0.0 2.8 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Arm PF00514.23 EGB10239.1 - 1.6e-35 120.1 58.1 2.3e-06 27.4 0.0 18.4 20 0 0 20 20 20 11 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGB10239.1 - 1.5e-05 25.1 0.6 0.022 14.8 0.0 4.2 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGB10239.1 - 0.00049 20.1 47.4 0.099 13.0 0.2 11.9 12 0 0 12 12 12 4 HEAT repeat RICTOR_N PF14664.6 EGB10239.1 - 0.2 10.6 20.1 0.43 9.5 1.5 4.8 3 1 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_2 PF13646.6 EGB10239.1 - 9.1 6.7 44.1 1.4 9.4 0.1 9.5 8 3 2 10 10 10 0 HEAT repeats Mito_carr PF00153.27 EGB10240.1 - 1e-13 51.0 3.3 0.00083 19.2 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ATG22 PF11700.8 EGB10241.1 - 8.3e-33 113.7 18.9 1.1e-32 113.3 18.9 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGB10241.1 - 2.6e-18 66.1 53.9 3.3e-11 42.7 24.4 2.6 1 1 1 3 3 3 3 Major Facilitator Superfamily VWA PF00092.28 EGB10242.1 - 0.00084 19.6 0.1 0.0016 18.7 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain MCM PF00493.23 EGB10243.1 - 1.1e-52 178.4 0.0 1.7e-43 148.3 0.0 2.0 2 0 0 2 2 2 2 MCM P-loop domain AAA_5 PF07728.14 EGB10243.1 - 1.8e-06 28.0 0.0 2.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGB10243.1 - 0.00038 19.9 0.0 0.46 9.8 0.0 2.1 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGB10243.1 - 0.00045 20.0 0.1 0.0076 16.0 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGB10243.1 - 0.0025 18.2 0.4 0.0058 17.0 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 EGB10243.1 - 0.0029 17.4 0.1 0.02 14.8 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGB10243.1 - 0.0039 16.9 0.8 0.007 16.1 0.8 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGB10243.1 - 0.0042 16.8 0.0 0.0081 15.9 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGB10243.1 - 0.0068 16.7 0.0 1.4 9.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 EGB10243.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EGB10243.1 - 0.056 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGB10243.1 - 0.064 13.5 0.0 0.51 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran_CTD PF16326.5 EGB10244.1 - 0.17 12.1 4.7 0.25 11.6 3.0 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain DEAD PF00270.29 EGB10246.1 - 1e-42 145.9 0.0 1.4e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB10246.1 - 1.9e-21 76.5 0.0 4.3e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MEDS PF14417.6 EGB10246.1 - 0.025 14.4 1.0 0.077 12.8 1.0 1.8 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ResIII PF04851.15 EGB10246.1 - 0.055 13.5 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MORN PF02493.20 EGB10247.1 - 4.1e-30 101.9 22.2 6.7e-06 25.7 0.0 7.1 7 0 0 7 7 7 7 MORN repeat ID PF18543.1 EGB10247.1 - 0.047 13.7 5.9 18 5.4 0.1 4.6 5 0 0 5 5 5 0 Intracellular delivery domain DUF3440 PF11922.8 EGB10247.1 - 0.16 11.6 0.0 0.76 9.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3440) AAA PF00004.29 EGB10248.1 - 3.8e-12 46.8 0.0 9.8e-05 22.8 0.0 2.5 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 EGB10248.1 - 3e-06 27.3 0.0 6.6e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 EGB10248.1 - 0.00096 19.6 1.9 0.0069 16.8 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGB10248.1 - 0.0095 15.9 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EGB10248.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EGB10248.1 - 0.013 15.7 0.1 0.071 13.3 0.0 2.3 2 1 0 3 3 3 0 AAA domain NACHT PF05729.12 EGB10248.1 - 0.024 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EGB10248.1 - 0.034 14.4 0.0 0.099 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SelB-wing_2 PF09106.11 EGB10248.1 - 0.082 13.1 0.3 0.082 13.1 0.3 2.7 3 0 0 3 3 3 0 Elongation factor SelB, winged helix AAA_28 PF13521.6 EGB10248.1 - 0.091 13.0 2.2 0.19 11.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGB10248.1 - 0.12 12.9 0.0 0.48 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGB10248.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGB10248.1 - 0.23 11.9 0.0 0.39 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase HAD_2 PF13419.6 EGB10249.1 - 2.1e-19 70.3 0.0 5.8e-19 68.9 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB10249.1 - 1.4e-12 48.4 0.7 3.5e-12 47.1 0.7 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB10249.1 - 2.1e-08 34.1 0.2 5.9e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Pkinase PF00069.25 EGB10250.1 - 5e-30 104.7 0.0 6.6e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10250.1 - 4.6e-05 22.8 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB10250.1 - 0.0062 16.5 0.4 0.02 14.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB10250.1 - 0.18 10.5 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Cys_Met_Meta_PP PF01053.20 EGB10251.1 - 4.5e-122 407.3 0.1 5.2e-122 407.1 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGB10251.1 - 8.4e-07 28.6 2.7 8.9e-07 28.5 1.5 1.5 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGB10251.1 - 2.7e-06 26.8 0.0 4.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGB10251.1 - 1e-05 24.7 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Proteasome PF00227.26 EGB10252.1 - 4e-41 140.6 0.2 5.1e-41 140.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB10252.1 - 2.2e-11 43.2 0.0 5.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Metallophos PF00149.28 EGB10254.1 - 5.6e-39 134.8 0.0 6.8e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGB10254.1 - 1.5e-14 54.2 0.0 3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Sulfotransfer_1 PF00685.27 EGB10255.1 - 0.0021 17.6 0.0 0.089 12.3 0.0 2.5 2 1 0 3 3 3 2 Sulfotransferase domain Kinesin PF00225.23 EGB10256.1 - 1.1e-89 300.6 0.0 1.3e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB10256.1 - 1.5e-15 57.4 0.0 2.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding YfkD PF14167.6 EGB10256.1 - 0.26 10.4 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 YfkD-like protein NHL PF01436.21 EGB10257.1 - 6.8e-18 63.7 7.2 7.1e-06 25.8 0.2 5.7 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 EGB10257.1 - 0.0003 20.4 0.0 0.0018 17.9 0.0 2.2 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EGB10257.1 - 0.018 15.2 0.0 3 8.1 0.0 3.1 4 0 0 4 4 4 0 Arylesterase DUF4597 PF15366.6 EGB10257.1 - 0.046 13.5 0.2 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) zf-HYPF PF07503.12 EGB10257.1 - 0.19 11.5 1.3 0.34 10.7 0.2 1.9 2 0 0 2 2 2 0 HypF finger MMS1_N PF10433.9 EGB10258.1 - 7.8e-136 453.6 0.0 1.1e-135 453.0 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGB10258.1 - 9.8e-78 261.7 0.0 1.7e-77 260.9 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region eIF2_C PF09173.11 EGB10259.1 - 1.9e-35 121.0 0.8 1.9e-35 121.0 0.8 1.9 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGB10259.1 - 2e-23 83.0 0.4 1.7e-22 79.9 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGB10259.1 - 3.5e-10 40.1 1.9 6.2e-10 39.3 0.8 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGB10259.1 - 0.0035 17.4 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB10259.1 - 0.019 14.9 0.3 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 EGB10259.1 - 0.11 12.5 0.2 0.53 10.3 0.1 2.0 1 1 0 2 2 2 0 Dynamin family CHORD PF04968.12 EGB10260.1 - 6.1e-34 116.5 19.3 1.2e-17 64.4 5.4 2.2 2 0 0 2 2 2 2 CHORD EF-hand_1 PF00036.32 EGB10261.1 - 3.1e-35 117.1 19.4 1.9e-09 36.4 1.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB10261.1 - 1.2e-30 105.8 11.8 2.2e-16 60.0 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB10261.1 - 2.5e-27 92.4 11.6 1.2e-09 37.3 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGB10261.1 - 9e-26 89.5 12.3 3.3e-12 46.1 1.3 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB10261.1 - 3.6e-18 64.1 18.6 4.5e-06 25.9 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGB10261.1 - 3.7e-16 59.2 0.5 7.6e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGB10261.1 - 2e-06 27.7 8.6 0.2 11.6 1.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB10261.1 - 0.00026 21.3 2.2 0.14 12.5 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EGB10261.1 - 0.00043 20.6 1.9 0.26 11.7 0.3 2.5 1 1 1 2 2 2 2 EF-hand domain SurA_N_3 PF13624.6 EGB10261.1 - 0.00047 20.0 2.0 0.22 11.3 0.2 2.1 1 1 1 2 2 2 2 SurA N-terminal domain Dockerin_1 PF00404.18 EGB10261.1 - 0.0005 20.2 0.4 0.54 10.5 0.2 2.4 2 0 0 2 2 2 2 Dockerin type I domain PMBR PF09373.10 EGB10261.1 - 0.0067 16.5 1.1 40 4.6 0.0 4.7 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF853 PF05872.12 EGB10261.1 - 0.0074 14.9 0.2 0.27 9.8 0.0 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) SurA_N_2 PF13623.6 EGB10261.1 - 0.012 15.5 3.3 1 9.2 0.3 2.7 1 1 1 2 2 2 0 SurA N-terminal domain Sigma54_CBD PF04963.13 EGB10261.1 - 0.014 15.2 0.4 0.018 14.9 0.4 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Caleosin PF05042.13 EGB10261.1 - 0.015 15.2 1.7 7 6.5 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein SUB1_ProdP9 PF18213.1 EGB10261.1 - 0.023 14.5 0.3 0.023 14.5 0.3 2.0 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 TerB PF05099.13 EGB10261.1 - 0.04 13.9 5.3 0.18 11.7 0.1 3.0 1 1 2 3 3 3 0 Tellurite resistance protein TerB DUF892 PF05974.12 EGB10261.1 - 0.084 12.9 2.3 0.86 9.6 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF892) EF-hand_11 PF08976.11 EGB10261.1 - 0.089 13.7 0.3 18 6.2 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain LETM1 PF07766.13 EGB10261.1 - 0.09 12.1 2.2 0.31 10.3 1.9 2.1 1 1 1 2 2 2 0 LETM1-like protein DUF3008 PF11450.8 EGB10261.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.5 3 0 0 3 3 2 0 Protein of unknwon function (DUF3008) FlgD PF03963.14 EGB10261.1 - 0.13 12.6 0.5 0.65 10.4 0.2 2.1 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF21 PF01595.20 EGB10261.1 - 0.24 11.1 0.4 0.68 9.6 0.2 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain MgtE_N PF03448.17 EGB10261.1 - 0.41 11.3 4.3 0.29 11.8 1.1 2.3 2 1 0 2 2 2 0 MgtE intracellular N domain Gp-FAR-1 PF05823.12 EGB10261.1 - 0.66 10.3 5.8 0.93 9.8 0.2 2.9 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Phg_2220_C PF09524.10 EGB10261.1 - 0.72 10.0 3.4 3.4 7.8 0.1 2.5 2 1 1 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Pkinase PF00069.25 EGB10262.1 - 8.2e-48 163.1 0.0 1.5e-47 162.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10262.1 - 2e-31 109.3 0.0 5.4e-30 104.5 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB10262.1 - 1.2e-05 24.8 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB10262.1 - 0.0052 15.6 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGB10262.1 - 0.015 14.9 0.2 0.029 14.0 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 EGB10262.1 - 0.028 13.5 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGB10262.1 - 0.093 12.1 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB10262.1 - 0.1 12.5 0.5 0.28 11.1 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family PP2C PF00481.21 EGB10263.1 - 2.1e-60 204.5 0.3 2.4e-60 204.3 0.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGB10263.1 - 0.0021 18.0 0.4 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) NIR_SIR PF01077.22 EGB10264.1 - 3.6e-44 150.1 0.0 1.5e-38 131.8 0.0 2.5 2 1 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EGB10264.1 - 2.7e-20 72.0 0.1 1.1e-12 47.7 0.0 3.0 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Peptidase_C2 PF00648.21 EGB10265.1 - 3e-28 98.7 0.0 3.2e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Arm PF00514.23 EGB10266.1 - 2.1e-30 103.8 5.1 8.6e-08 32.0 0.3 4.1 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGB10266.1 - 1.2e-11 43.8 2.0 0.029 14.6 0.0 4.2 4 0 0 4 4 4 4 HEAT repeat HEAT_EZ PF13513.6 EGB10266.1 - 3e-09 37.2 7.4 0.04 14.4 0.1 4.1 3 1 1 4 4 4 4 HEAT-like repeat HEAT_2 PF13646.6 EGB10266.1 - 3.6e-07 30.5 9.1 7.4e-05 23.1 3.5 2.8 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 EGB10266.1 - 3.3e-05 24.1 6.2 0.33 11.7 0.4 5.0 5 2 0 5 5 5 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 EGB10266.1 - 0.0017 18.3 0.0 0.67 10.0 0.0 2.4 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain DUF5578 PF17741.1 EGB10266.1 - 0.14 11.5 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5578) KAP PF05804.12 EGB10266.1 - 0.21 9.7 0.0 0.39 8.8 0.0 1.4 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) Tubulin PF00091.25 EGB10267.1 - 2e-51 175.0 0.0 2.7e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB10267.1 - 2.1e-18 66.7 0.0 5.7e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 Tubulin C-terminal domain LRR_8 PF13855.6 EGB10269.1 - 2.8e-21 75.0 19.8 9.6e-10 38.1 3.2 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGB10269.1 - 8.5e-18 64.2 9.6 4.4e-06 26.9 1.8 3.2 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB10269.1 - 1.7e-07 30.8 12.1 0.88 10.4 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.6 EGB10269.1 - 4.8e-07 29.4 2.9 0.0014 18.1 0.2 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EGB10269.1 - 0.049 13.7 12.1 0.96 9.7 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat SF3A3 PF16837.5 EGB10269.1 - 0.06 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 AAA_11 PF13086.6 EGB10271.1 - 4.3e-36 125.0 0.0 1.5e-20 74.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 EGB10271.1 - 7.8e-36 123.6 0.0 1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB10271.1 - 2.1e-14 53.7 4.7 2.1e-14 53.7 4.7 3.9 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EGB10271.1 - 4.4e-09 36.8 0.1 2.9e-08 34.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EGB10271.1 - 2e-06 27.5 0.0 5.8e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGB10271.1 - 2.1e-06 27.7 0.0 0.53 10.0 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EGB10271.1 - 2.6e-06 27.4 0.2 5.5e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 Helicase CbiA PF01656.23 EGB10271.1 - 0.0034 17.4 1.9 0.048 13.7 0.2 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 EGB10271.1 - 0.0046 16.4 0.0 0.03 13.8 0.1 2.0 2 0 0 2 2 2 1 PhoH-like protein MeaB PF03308.16 EGB10271.1 - 0.0075 15.3 0.2 0.014 14.4 0.2 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EGB10271.1 - 0.013 15.9 1.4 0.013 15.9 1.4 2.7 2 2 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 EGB10271.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 2 0 0 2 2 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 EGB10271.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EGB10271.1 - 0.02 14.6 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 EGB10271.1 - 0.03 14.3 0.0 0.084 12.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EGB10271.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB10271.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 1 0 NACHT domain NTPase_1 PF03266.15 EGB10271.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NTPase MobB PF03205.14 EGB10271.1 - 0.053 13.4 0.1 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 EGB10271.1 - 0.067 12.4 0.2 0.25 10.6 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGB10271.1 - 0.071 13.4 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGB10271.1 - 0.079 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGB10271.1 - 0.13 12.5 3.5 0.19 12.0 0.0 3.1 3 1 0 3 3 3 0 AAA domain ATPase PF06745.13 EGB10271.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 KaiC Ank_2 PF12796.7 EGB10272.1 - 1.1e-18 67.6 5.6 1.3e-10 41.7 1.7 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10272.1 - 2.6e-13 50.2 6.2 0.00011 22.6 1.1 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB10272.1 - 8.6e-10 38.7 9.7 0.0014 18.9 0.2 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10272.1 - 4e-09 36.0 6.8 0.036 14.6 0.0 5.9 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EGB10272.1 - 0.0029 18.0 16.2 0.59 10.7 0.2 5.3 5 0 0 5 5 5 2 Ankyrin repeat TSGP1 PF07771.11 EGB10273.1 - 0.15 12.2 11.0 1.4 9.1 3.7 2.6 2 0 0 2 2 2 0 Tick salivary peptide group 1 Got1 PF04178.12 EGB10274.1 - 6.2e-31 107.1 9.0 7.6e-31 106.9 9.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family tRNA-synt_1 PF00133.22 EGB10275.1 - 1.5e-194 647.6 0.0 3.4e-193 643.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGB10275.1 - 1.2e-30 106.5 0.0 1.9e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGB10275.1 - 2.3e-20 72.7 0.0 5.6e-07 28.6 0.0 3.9 4 0 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 EGB10275.1 - 1.8e-17 63.3 2.0 3.3e-17 62.5 2.0 1.5 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 EGB10275.1 - 5.4e-09 35.8 0.0 2e-07 30.7 0.0 2.2 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 EGB10275.1 - 0.0027 16.7 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 EGB10275.1 - 0.01 15.2 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain FtsQ PF03799.15 EGB10275.1 - 0.012 16.5 0.0 0.029 15.2 0.0 1.7 1 0 0 1 1 1 0 Cell division protein FtsQ ABC_tran_CTD PF16326.5 EGB10275.1 - 0.12 12.7 0.6 0.27 11.5 0.6 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain DASH_Spc19 PF08287.11 EGB10275.1 - 0.25 11.2 0.2 0.42 10.5 0.2 1.2 1 0 0 1 1 1 0 Spc19 Armet PF10208.9 EGB10276.1 - 4.6e-29 101.2 6.9 7.6e-29 100.5 6.9 1.3 1 1 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 EGB10276.1 - 0.0033 17.1 0.3 0.0067 16.2 0.3 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EGB10276.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Telomere_Sde2_2 PF13297.6 EGB10276.1 - 0.066 12.9 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Telomere stability C-terminal NAD_binding_1 PF00175.21 EGB10277.1 - 2.7e-20 73.0 0.0 3.8e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGB10277.1 - 5.7e-13 49.0 0.0 9.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGB10277.1 - 1.1e-05 25.6 0.1 0.16 12.1 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EGB10278.1 - 1.4e-25 90.0 0.0 2.3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 EGB10278.1 - 0.007 16.0 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_6 PF00970.24 EGB10278.1 - 0.026 14.9 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Dcc1 PF09724.9 EGB10279.1 - 2.1e-36 125.9 0.0 3e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Arm PF00514.23 EGB10280.1 - 1.1e-54 180.8 35.6 7.8e-11 41.6 0.1 9.5 8 1 1 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 EGB10280.1 - 1.7e-18 65.9 0.0 3.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 EGB10280.1 - 1.3e-15 57.5 21.6 3.6e-07 30.6 0.1 5.6 6 1 0 6 6 6 3 HEAT-like repeat IBB PF01749.20 EGB10280.1 - 6.8e-13 48.9 1.1 1.8e-12 47.5 0.4 2.1 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 EGB10280.1 - 2.3e-11 43.9 16.2 8e-06 26.2 0.1 5.6 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.22 EGB10280.1 - 4.8e-09 35.7 13.9 0.00017 21.6 0.0 8.6 9 0 0 9 9 9 1 HEAT repeat RICTOR_V PF14668.6 EGB10280.1 - 0.00081 19.6 0.0 0.0072 16.5 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.7 EGB10280.1 - 0.0035 17.4 0.1 5.8 6.9 0.1 3.3 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DCB PF16213.5 EGB10280.1 - 0.025 14.2 0.0 0.085 12.5 0.0 1.9 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 HEAT_PBS PF03130.16 EGB10280.1 - 4.6 8.2 13.7 2.8 8.8 0.6 5.5 6 1 0 6 6 6 0 PBS lyase HEAT-like repeat GMC_oxred_N PF00732.19 EGB10281.1 - 4.1e-36 124.9 0.1 3.1e-33 115.4 0.1 3.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGB10281.1 - 5.6e-32 111.2 0.5 1.7e-31 109.7 0.5 1.9 1 0 0 1 1 1 1 GMC oxidoreductase FmiP_Thoc5 PF09766.9 EGB10281.1 - 1.5e-28 100.1 0.0 2.8e-22 79.5 0.0 2.1 2 0 0 2 2 2 2 Fms-interacting protein/Thoc5 PC-Esterase PF13839.6 EGB10281.1 - 3.5e-05 23.7 0.0 0.00058 19.7 0.0 2.1 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p NAD_binding_8 PF13450.6 EGB10281.1 - 0.00015 22.0 0.8 0.00083 19.5 0.8 2.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGB10281.1 - 0.00072 18.9 0.3 0.0019 17.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB10281.1 - 0.0027 16.9 0.1 0.0042 16.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGB10281.1 - 0.0081 14.9 0.2 0.013 14.3 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EGB10281.1 - 0.018 14.1 0.3 0.018 14.1 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein PhyH PF05721.13 EGB10282.1 - 1.3e-13 51.7 0.3 2.3e-13 50.9 0.3 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 EGB10282.1 - 0.058 13.2 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family DUF16 PF01519.16 EGB10283.1 - 0.0016 18.9 2.3 0.014 15.8 0.7 3.1 2 1 1 3 3 3 1 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 EGB10283.1 - 0.0023 18.3 2.5 1.1 9.7 0.5 4.0 2 1 1 3 3 3 2 Snapin/Pallidin DUF1664 PF07889.12 EGB10283.1 - 0.018 15.1 7.4 0.16 12.0 1.6 3.9 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EGB10283.1 - 0.028 14.7 4.4 2 8.8 1.2 3.9 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mito_fiss_reg PF05308.11 EGB10283.1 - 0.034 14.2 0.6 0.034 14.2 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator zf-C4H2 PF10146.9 EGB10283.1 - 0.065 13.5 3.6 3.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein Sec8_exocyst PF04048.14 EGB10283.1 - 0.18 11.7 1.4 0.4 10.6 0.7 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF4763 PF15960.5 EGB10283.1 - 0.64 9.3 6.9 0.071 12.4 0.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) Baculo_PEP_C PF04513.12 EGB10283.1 - 1.1 9.4 9.7 12 6.0 0.1 3.9 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus EMP24_GP25L PF01105.24 EGB10283.1 - 1.1 9.1 2.3 1.8 8.5 0.1 2.4 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 EGB10283.1 - 1.6 7.5 25.8 0.91 8.3 6.9 3.3 2 2 0 3 3 3 0 Spc7 kinetochore protein Gp58 PF07902.11 EGB10283.1 - 2.2 6.4 5.0 0.62 8.3 1.0 1.9 2 0 0 2 2 2 0 gp58-like protein Atg14 PF10186.9 EGB10283.1 - 2.6 7.0 9.7 0.16 11.0 1.1 2.5 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 EGB10283.1 - 5.5 7.5 10.4 8.6 6.9 0.9 4.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein SPRY PF00622.28 EGB10284.1 - 7.6e-08 32.5 0.1 3.8e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 SPRY domain FA_hydroxylase PF04116.13 EGB10285.1 - 1.2e-09 38.6 7.9 1.5e-09 38.3 7.9 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Pkinase_Tyr PF07714.17 EGB10286.1 - 1.4e-47 162.2 0.0 1.6e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB10286.1 - 2.3e-45 155.0 0.0 2.8e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGB10286.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB10286.1 - 0.0029 16.4 0.0 0.0039 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB10286.1 - 0.015 15.2 0.7 0.015 15.2 0.7 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB10286.1 - 0.024 14.0 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EGB10286.1 - 0.15 11.0 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain ketoacyl-synt PF00109.26 EGB10287.1 - 6.7e-37 127.4 0.6 1.2e-36 126.6 0.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB10287.1 - 1.4e-25 89.6 0.0 3.2e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EGB10287.1 - 7.6e-21 74.5 0.5 1.6e-20 73.4 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB10287.1 - 6.5e-12 45.5 0.5 1.3e-11 44.5 0.5 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GalP_UDP_transf PF01087.22 EGB10287.1 - 1.4e-08 35.3 0.0 2.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain KR PF08659.10 EGB10287.1 - 1.4e-06 28.3 1.0 2.6e-06 27.5 1.0 1.4 1 0 0 1 1 1 1 KR domain DUF4931 PF16285.5 EGB10287.1 - 0.046 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) FliN_N PF16973.5 EGB10287.1 - 0.06 13.2 2.8 0.14 12.0 2.8 1.6 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal KAsynt_C_assoc PF16197.5 EGB10287.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension zf-C3HC4_3 PF13920.6 EGB10287.1 - 2.2 8.2 7.7 0.2 11.6 1.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2353 PF09789.9 EGB10288.1 - 0.0016 17.9 4.9 0.0016 17.9 4.9 2.2 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.15 EGB10288.1 - 0.018 14.8 8.3 0.057 13.2 0.3 4.5 3 2 1 4 4 4 0 Septum formation initiator DUF2205 PF10224.9 EGB10288.1 - 0.025 14.6 1.5 0.089 12.8 0.5 2.4 2 0 0 2 2 2 0 Short coiled-coil protein Sec7_N PF12783.7 EGB10288.1 - 0.16 11.9 0.2 26 4.7 0.0 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PHM7_cyt PF14703.6 EGB10288.1 - 0.55 10.5 6.8 1.1 9.4 0.8 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter BST2 PF16716.5 EGB10288.1 - 1.8 9.2 5.3 34 5.1 0.0 3.6 4 0 0 4 4 4 0 Bone marrow stromal antigen 2 TolA_bind_tri PF16331.5 EGB10288.1 - 4.5 7.4 9.9 0.65 10.1 1.2 3.2 3 1 0 3 3 3 0 TolA binding protein trimerisation Sulfatase PF00884.23 EGB10289.1 - 1.5e-24 87.0 0.0 1.6e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Sulfatase PGK PF00162.19 EGB10290.1 - 5.1e-143 476.6 0.3 5.9e-143 476.4 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Castor_Poll_mid PF06241.12 EGB10291.1 - 3.3e-11 43.1 0.0 1.1e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel ATP-synt_Eps PF04627.13 EGB10291.1 - 0.0021 18.0 1.3 0.0069 16.3 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain PmbA_TldD PF01523.16 EGB10291.1 - 0.83 9.4 4.8 2.2 8.0 4.8 1.8 1 0 0 1 1 1 0 Putative modulator of DNA gyrase GMC_oxred_C PF05199.13 EGB10292.1 - 1.5e-38 132.6 0.2 1.7e-38 132.4 0.2 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Patched PF02460.18 EGB10293.1 - 2.4e-41 141.7 2.1 5.5e-22 77.7 0.1 2.3 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EGB10293.1 - 3.3e-17 62.7 28.2 5e-17 62.1 15.9 3.2 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation PAP_assoc PF03828.19 EGB10293.1 - 1.6e-05 25.0 0.0 3.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGB10293.1 - 0.00024 21.3 0.0 0.0005 20.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SecD_SecF PF02355.16 EGB10293.1 - 5.5 6.3 18.1 1.4 8.3 7.5 2.6 2 1 0 2 2 2 0 Protein export membrane protein DSPc PF00782.20 EGB10294.1 - 4.7e-23 81.5 0.0 5e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGB10294.1 - 0.028 14.7 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 EGB10294.1 - 0.083 12.8 0.4 0.08 12.9 0.4 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGB10294.1 - 0.18 11.3 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DEP PF00610.21 EGB10294.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Tyrosinase PF00264.20 EGB10295.1 - 3.6e-35 122.3 2.6 1.7e-34 120.0 2.6 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M10 PF00413.24 EGB10295.1 - 1.2e-21 77.2 0.0 4.5e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 Matrixin PG_binding_1 PF01471.18 EGB10295.1 - 0.0045 17.2 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Metallopep PF12044.8 EGB10295.1 - 0.031 12.9 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M54 PF07998.11 EGB10295.1 - 0.042 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_4 PF13583.6 EGB10295.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EGB10295.1 - 0.17 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Met-zincin NYD-SP28 PF14772.6 EGB10296.1 - 1.1e-18 67.1 17.6 1.1e-18 67.1 17.6 5.0 2 1 2 4 4 4 1 Sperm tail NYD-SP28_assoc PF14775.6 EGB10296.1 - 3.6e-12 46.2 0.3 3.6e-12 46.2 0.3 3.6 5 1 0 5 5 5 1 Sperm tail C-terminal domain Sacchrp_dh_NADP PF03435.18 EGB10297.1 - 4.4e-16 59.3 0.0 7.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGB10297.1 - 0.0019 18.1 0.2 0.0033 17.4 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGB10297.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Adap_comp_sub PF00928.21 EGB10298.1 - 4.3e-62 209.9 0.0 6e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGB10298.1 - 0.0013 18.6 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FKBP_C PF00254.28 EGB10299.1 - 2.7e-17 62.8 0.1 2.9e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 EGB10300.1 - 1.7e-24 86.6 0.0 2.1e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10300.1 - 1.1e-16 60.9 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB10300.1 - 8.2e-08 31.4 0.0 1.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB10300.1 - 0.00051 20.0 4.4 0.092 12.6 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family ABC1 PF03109.16 EGB10300.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Sel1 PF08238.12 EGB10301.1 - 2.8e-34 116.8 19.9 2.2e-09 37.7 0.0 6.5 6 1 0 6 6 6 6 Sel1 repeat TPR_12 PF13424.6 EGB10301.1 - 1.1e-06 28.9 4.4 0.0011 19.2 0.9 5.3 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB10301.1 - 5.5e-06 26.9 7.9 0.92 10.2 0.3 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGB10301.1 - 0.00028 21.3 13.0 5 8.0 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_5 PF12688.7 EGB10301.1 - 0.0025 18.1 2.7 9.4 6.5 0.1 4.4 3 2 1 4 4 4 1 Tetratrico peptide repeat TPR_7 PF13176.6 EGB10301.1 - 0.0025 17.7 11.8 1.1 9.4 0.0 6.3 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB10301.1 - 0.0026 17.5 0.3 0.0026 17.5 0.3 7.5 9 0 0 9 9 9 1 Tetratricopeptide repeat PPR_2 PF13041.6 EGB10301.1 - 0.0061 16.7 2.7 2.4 8.4 0.0 3.5 5 0 0 5 5 4 2 PPR repeat family TPR_14 PF13428.6 EGB10301.1 - 0.0082 16.9 12.5 5 8.2 0.1 5.8 2 1 4 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EGB10301.1 - 0.052 13.6 6.1 5.8 7.1 0.0 4.7 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 EGB10301.1 - 0.09 13.1 9.7 7 7.1 0.1 5.0 6 0 0 6 6 6 0 PPR repeat TPR_2 PF07719.17 EGB10301.1 - 0.11 12.7 0.4 0.11 12.7 0.4 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB10301.1 - 0.16 12.4 5.0 7.7 7.1 0.0 4.2 4 2 0 4 4 4 0 Tetratricopeptide repeat VIT PF08487.10 EGB10301.1 - 0.52 10.5 2.5 88 3.4 0.0 3.5 2 1 2 4 4 4 0 Vault protein inter-alpha-trypsin domain DUF1681 PF07933.14 EGB10302.1 - 4.1e-36 123.9 0.0 4.8e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Glyco_transf_8 PF01501.20 EGB10303.1 - 9.8e-13 48.2 0.0 1.5e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGB10303.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 EGB10303.1 - 0.096 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_24 PF18404.1 EGB10303.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Glucosyltransferase 24 LRR_8 PF13855.6 EGB10304.1 - 7.4e-16 57.7 10.4 1.1e-11 44.3 2.8 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGB10304.1 - 9.7e-10 38.6 3.3 0.00037 20.8 0.1 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB10304.1 - 1.5e-07 31.1 0.5 1.5e-07 31.1 0.5 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 EGB10304.1 - 0.0074 16.3 3.2 1.5 9.1 0.1 3.7 3 1 1 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 EGB10304.1 - 0.0078 16.6 2.1 6.3 7.8 0.1 3.0 3 1 0 3 3 3 2 Leucine Rich Repeat CREPT PF16566.5 EGB10304.1 - 0.041 14.0 0.1 0.4 10.8 0.0 2.1 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour FMN_dh PF01070.18 EGB10306.1 - 1.3e-108 363.2 0.0 1.5e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGB10306.1 - 8.7e-07 28.3 0.5 0.00013 21.1 0.6 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EGB10306.1 - 0.00012 21.5 0.4 0.0002 20.8 0.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EGB10306.1 - 0.00069 18.9 0.5 0.00099 18.3 0.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EGB10306.1 - 0.088 12.0 0.0 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_Phos_1 PF00300.22 EGB10307.1 - 7.1e-29 100.9 0.0 1.1e-17 64.4 0.3 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) EF-hand_6 PF13405.6 EGB10307.1 - 0.0059 16.4 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain DinB_2 PF12867.7 EGB10307.1 - 0.0085 16.6 0.0 0.027 15.0 0.0 1.9 1 0 0 1 1 1 1 DinB superfamily His_Phos_2 PF00328.22 EGB10307.1 - 0.015 14.7 0.0 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) EF-hand_1 PF00036.32 EGB10307.1 - 0.084 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EGB10307.1 - 0.2 12.1 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Glyco_transf_41 PF13844.6 EGB10308.1 - 3.3e-06 25.8 0.0 5.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 41 zf-CCHC_5 PF14787.6 EGB10308.1 - 0.22 11.2 2.7 0.51 10.1 2.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PIP5K PF01504.18 EGB10309.1 - 4e-61 206.7 0.0 4.1e-47 160.7 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Amino_oxidase PF01593.24 EGB10310.1 - 1.4e-53 182.8 3.7 3.2e-53 181.6 3.7 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase PqiA PF04403.13 EGB10310.1 - 2.6e-16 59.9 15.7 1.5e-10 41.1 0.6 3.4 3 0 0 3 3 3 2 Paraquat-inducible protein A NAD_binding_8 PF13450.6 EGB10310.1 - 1.7e-06 28.1 1.2 9.4e-06 25.8 1.2 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGB10310.1 - 0.0067 15.7 0.1 0.013 14.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family PWWP PF00855.17 EGB10310.1 - 0.065 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 PWWP domain Trypan_PARP PF05887.11 EGB10310.1 - 4.8 7.2 34.9 0.0064 16.5 14.7 4.1 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Prenyltransf PF01255.19 EGB10313.1 - 4.1e-64 216.2 0.0 4.6e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase dsDNA_bind PF01984.20 EGB10314.1 - 2.4e-24 85.8 7.9 2.9e-24 85.5 7.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain SPACA7 PF15307.6 EGB10314.1 - 0.03 14.6 0.5 0.038 14.2 0.5 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 Asp2 PF16929.5 EGB10315.1 - 0.00023 20.3 0.0 0.00033 19.8 0.0 1.1 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Lipase_GDSL_2 PF13472.6 EGB10315.1 - 0.00042 20.8 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Hydrolase_4 PF12146.8 EGB10315.1 - 0.055 12.7 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 EGB10315.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FERM_f0 PF16511.5 EGB10315.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM HECT PF00632.25 EGB10316.1 - 6.6e-66 222.9 0.0 8.1e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps36-NZF-N PF16988.5 EGB10316.1 - 0.052 13.0 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase_Tyr PF07714.17 EGB10317.1 - 3.5e-44 151.0 0.0 1e-43 149.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB10317.1 - 1.1e-37 129.9 0.0 1.3e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGB10317.1 - 0.0019 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0016 PF01169.19 EGB10318.1 - 3.4e-45 152.2 18.0 6.7e-23 80.8 2.5 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 OFeT_1 PF16955.5 EGB10318.1 - 0.0052 16.5 0.1 0.0083 15.8 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron uptake permease, iron-lead transporter Pkinase PF00069.25 EGB10319.1 - 1.4e-57 195.1 0.0 1.6e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10319.1 - 1e-22 80.7 0.0 1.3e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGB10319.1 - 0.057 12.5 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EGB10319.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Rnk_N PF14760.6 EGB10320.1 - 0.053 14.0 8.2 2.3 8.7 1.4 3.2 2 0 0 2 2 2 0 Rnk N-terminus Myb_DNA-bind_7 PF15963.5 EGB10320.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Myb DNA-binding like 2-Hacid_dh_C PF02826.19 EGB10321.1 - 6e-42 143.0 0.0 7e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGB10321.1 - 0.0031 18.1 0.0 0.0066 17.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 EGB10321.1 - 0.0039 17.3 0.0 0.0071 16.4 0.0 1.3 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 EGB10321.1 - 0.021 15.3 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain DUF2196 PF09962.9 EGB10322.1 - 3.4e-20 71.8 0.3 3.6e-20 71.7 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) DUF2866 PF11065.8 EGB10322.1 - 0.1 12.6 0.1 0.14 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2866) ARL2_Bind_BART PF11527.8 EGB10323.1 - 4.7e-07 29.9 0.1 9.1e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Tom22 PF04281.13 EGB10323.1 - 0.44 10.3 1.9 2.7 7.8 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 PhyH PF05721.13 EGB10326.1 - 1.7e-16 61.1 0.4 6e-16 59.3 0.4 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PTS-HPr PF00381.19 EGB10326.1 - 0.072 13.3 2.3 0.18 12.0 2.3 1.7 1 0 0 1 1 1 0 PTS HPr component phosphorylation site PFU PF09070.11 EGB10326.1 - 0.2 11.9 0.0 0.52 10.6 0.0 1.6 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Chloroa_b-bind PF00504.21 EGB10327.1 - 2.6e-25 89.8 0.1 3.4e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein IFT57 PF10498.9 EGB10329.1 - 7.3e-110 367.3 0.5 8.2e-110 367.2 0.5 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Occludin_ELL PF07303.13 EGB10329.1 - 0.00081 20.1 0.3 0.00081 20.1 0.3 2.0 2 1 0 2 2 1 1 Occludin homology domain TMPIT PF07851.13 EGB10329.1 - 0.02 14.2 4.5 0.028 13.7 4.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 EGB10329.1 - 0.023 14.7 5.4 0.041 13.9 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EGB10329.1 - 0.028 13.7 4.7 0.044 13.1 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 EGB10329.1 - 0.035 14.6 8.5 0.049 14.1 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 GAS PF13851.6 EGB10329.1 - 0.038 13.3 10.4 0.024 14.0 8.3 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 EGB10329.1 - 0.04 14.4 7.1 4.4 7.9 0.2 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 EGB10329.1 - 0.04 13.5 1.7 0.058 13.0 1.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nup88 PF10168.9 EGB10329.1 - 0.04 11.7 3.9 0.057 11.2 3.9 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF948 PF06103.11 EGB10329.1 - 0.069 13.4 2.2 0.55 10.5 2.1 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 EGB10329.1 - 0.11 11.5 5.0 0.29 10.2 5.0 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.5 EGB10329.1 - 0.12 11.9 8.8 0.18 11.2 8.8 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 EGB10329.1 - 0.32 9.8 11.5 0.33 9.8 9.5 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EGB10329.1 - 0.36 10.9 2.7 1 9.4 1.5 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 EGB10329.1 - 0.52 10.3 5.3 5.5 7.0 4.9 2.2 1 1 1 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.9 EGB10329.1 - 1.1 9.3 11.7 0.048 13.7 2.7 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC-167 PF15188.6 EGB10329.1 - 1.7 9.1 5.7 2.5 8.5 0.2 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF3391 PF11871.8 EGB10329.1 - 3.1 8.3 6.8 0.48 11.0 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) PTH2 PF01981.16 EGB10330.1 - 5.8e-43 145.9 0.8 6.8e-43 145.7 0.8 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Thioredoxin PF00085.20 EGB10331.1 - 8.5e-14 51.4 0.1 1.5e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin ABC_tran PF00005.27 EGB10332.1 - 1.1e-44 152.3 0.0 7.7e-23 81.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGB10332.1 - 2.4e-12 46.8 0.3 0.0022 17.4 0.1 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGB10332.1 - 4.3e-11 43.2 6.0 0.052 13.3 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGB10332.1 - 1.1e-07 32.5 12.1 0.0003 21.4 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 EGB10332.1 - 1.6e-06 27.8 0.5 0.0069 16.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EGB10332.1 - 1.7e-06 28.1 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_13 PF13166.6 EGB10332.1 - 3e-06 26.2 7.2 0.00067 18.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 EGB10332.1 - 1.6e-05 25.2 0.0 0.13 12.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGB10332.1 - 2.4e-05 24.6 3.7 0.039 14.2 0.1 3.2 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGB10332.1 - 2.4e-05 24.3 0.2 0.1 12.5 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_24 PF13479.6 EGB10332.1 - 6.8e-05 22.7 0.5 0.66 9.7 0.0 3.2 3 1 0 3 3 3 2 AAA domain cobW PF02492.19 EGB10332.1 - 7e-05 22.5 0.1 0.27 10.8 0.0 2.7 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EGB10332.1 - 8.3e-05 22.5 3.9 0.03 14.0 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 EGB10332.1 - 0.00034 21.1 0.3 1.9 8.9 0.0 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EGB10332.1 - 0.0004 20.4 0.2 0.081 13.0 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.14 EGB10332.1 - 0.00043 20.2 0.4 0.079 12.9 0.2 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran_Xtn PF12848.7 EGB10332.1 - 0.00048 20.1 10.2 0.00048 20.1 10.2 3.2 4 1 0 4 4 2 1 ABC transporter ATP-synt_ab PF00006.25 EGB10332.1 - 0.00048 19.8 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 EGB10332.1 - 0.00052 20.0 0.3 0.97 9.3 0.2 2.4 2 0 0 2 2 2 2 NTPase AAA_16 PF13191.6 EGB10332.1 - 0.0006 20.2 7.8 0.087 13.2 0.0 3.4 3 1 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 EGB10332.1 - 0.00064 19.9 0.2 0.26 11.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGB10332.1 - 0.00097 19.2 0.0 0.47 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGB10332.1 - 0.00099 19.5 0.0 1 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 EGB10332.1 - 0.0011 19.1 0.3 0.55 10.5 0.0 2.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EGB10332.1 - 0.0016 18.0 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 EGB10332.1 - 0.0016 18.2 3.6 0.76 9.5 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB10332.1 - 0.0019 18.8 0.8 0.2 12.2 0.0 3.5 4 0 0 4 4 3 1 AAA domain Arf PF00025.21 EGB10332.1 - 0.0022 17.4 0.5 0.41 10.1 0.0 2.7 3 0 0 3 3 2 1 ADP-ribosylation factor family SRPRB PF09439.10 EGB10332.1 - 0.0048 16.3 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 EGB10332.1 - 0.0096 15.3 0.1 4.3 6.7 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 EGB10332.1 - 0.015 15.0 0.4 2 8.2 0.1 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 EGB10332.1 - 0.017 14.5 0.0 0.9 8.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 EGB10332.1 - 0.018 15.0 0.5 8.1 6.5 0.0 3.0 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 EGB10332.1 - 0.036 13.9 0.1 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Pox_A32 PF04665.12 EGB10332.1 - 0.041 13.3 0.2 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein T2SSE PF00437.20 EGB10332.1 - 0.042 12.9 0.0 2.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 EGB10332.1 - 0.054 13.5 1.1 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EGB10332.1 - 0.063 12.4 2.8 4.1 6.5 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain ATPase_2 PF01637.18 EGB10332.1 - 0.082 12.8 0.6 8.1 6.3 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea DUF2895 PF11444.8 EGB10332.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) ResIII PF04851.15 EGB10332.1 - 0.097 12.7 1.1 4.7 7.2 0.0 3.0 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGB10332.1 - 0.33 11.3 3.2 13 6.1 0.2 2.9 2 2 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGB10332.1 - 0.37 10.4 6.0 2 8.0 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 EGB10332.1 - 1 9.4 4.0 7.9 6.5 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_11 PF13086.6 EGB10332.1 - 2 8.1 4.9 8.4 6.1 1.5 3.0 4 0 0 4 4 3 0 AAA domain p25-alpha PF05517.12 EGB10333.1 - 2.3e-13 50.6 0.0 3.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 p25-alpha WD40 PF00400.32 EGB10333.1 - 0.0099 16.7 7.1 0.74 10.8 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 EGB10333.1 - 2.5 8.7 13.8 11 6.7 3.0 5.0 4 0 0 4 4 4 0 PQQ-like domain SNF2_N PF00176.23 EGB10334.1 - 9.4e-40 136.4 0.0 4.3e-39 134.2 0.0 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.29 EGB10334.1 - 0.052 13.3 0.0 2.4 7.9 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 EGB10334.1 - 0.12 12.4 0.0 20 5.2 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_34 PF13872.6 EGB10334.1 - 0.2 10.5 0.0 1.1 8.1 0.0 1.9 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Helicase_C PF00271.31 EGB10335.1 - 1.1e-11 45.0 0.0 1.9e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_C1 PF00112.23 EGB10336.1 - 2.8e-58 197.6 0.1 3.7e-58 197.2 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB10336.1 - 5.2e-13 49.2 2.5 9.4e-13 48.4 2.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB10336.1 - 0.00016 20.6 0.8 0.0053 15.6 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family FtsJ PF01728.19 EGB10337.1 - 3.5e-12 46.8 0.0 5.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 EGB10337.1 - 0.0053 17.8 1.0 0.028 15.5 0.1 2.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB10337.1 - 0.08 13.7 0.5 0.26 12.0 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_47 PF01532.20 EGB10338.1 - 1.6e-105 353.7 0.0 1.9e-105 353.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_2_C PF02836.17 EGB10339.1 - 7.2e-31 107.4 0.0 1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EGB10339.1 - 5.5e-06 26.4 0.0 1.4e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EGB10339.1 - 0.0027 18.4 0.0 0.0048 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 PfkB PF00294.24 EGB10341.1 - 2.7e-55 187.8 0.2 3.5e-55 187.4 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase His_Phos_1 PF00300.22 EGB10342.1 - 3.3e-15 56.3 0.3 2e-14 53.8 0.3 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Transposase_28 PF04195.12 EGB10342.1 - 0.021 15.1 0.1 0.034 14.4 0.1 1.3 1 0 0 1 1 1 0 Putative gypsy type transposon His_Phos_2 PF00328.22 EGB10342.1 - 0.031 13.6 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Fumerase_C PF05683.12 EGB10343.1 - 5.7e-84 280.5 0.0 8.1e-84 280.0 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 EGB10343.1 - 2.3e-78 263.4 0.0 2.8e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Glyco_transf_8 PF01501.20 EGB10344.1 - 0.00025 20.7 0.0 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Zn_ribbon_recom PF13408.6 EGB10344.1 - 0.24 11.9 7.0 0.48 11.0 7.0 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain CAP_N PF01213.19 EGB10344.1 - 0.25 10.8 5.2 0.41 10.1 5.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Tnp_DNA_bind PF14706.6 EGB10344.1 - 0.53 10.2 18.6 2.7 7.9 0.0 5.7 4 1 3 7 7 7 0 Transposase DNA-binding ABC1 PF03109.16 EGB10345.1 - 2.4e-26 92.2 0.0 4.2e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGB10345.1 - 0.0045 16.6 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EGB10345.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10345.1 - 0.02 14.2 0.1 0.079 12.2 0.1 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase PCI PF01399.27 EGB10346.1 - 7.6e-12 45.7 0.0 1.7e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain HA2 PF04408.23 EGB10347.1 - 7.9e-16 58.3 0.1 1.5e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGB10347.1 - 3.6e-13 49.8 0.0 6.8e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGB10347.1 - 4.8e-07 30.1 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EGB10347.1 - 0.00034 20.9 0.0 0.001 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EGB10347.1 - 0.0034 17.2 0.0 0.021 14.6 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGB10347.1 - 0.0047 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGB10347.1 - 0.13 12.8 0.0 0.36 11.3 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EGB10347.1 - 3.2 8.1 6.8 1.4 9.3 1.2 3.1 2 2 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EGB10348.1 - 6.1e-19 68.9 0.0 8.9e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB10348.1 - 0.0027 18.1 2.4 0.0029 18.0 0.4 2.1 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGB10348.1 - 0.003 17.5 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EGB10348.1 - 0.062 13.6 0.1 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGB10348.1 - 0.084 12.4 0.4 0.24 10.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain PAE PF03283.13 EGB10349.1 - 2.6e-29 102.5 0.3 3.2e-29 102.2 0.3 1.1 1 0 0 1 1 1 1 Pectinacetylesterase Nbl1_Borealin_N PF10444.9 EGB10350.1 - 2.5e-10 39.8 0.6 2.5e-10 39.8 0.6 1.8 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Borealin PF10512.9 EGB10350.1 - 8.9e-08 32.1 5.2 5.5e-05 23.1 3.4 2.8 2 1 0 2 2 2 1 Cell division cycle-associated protein 8 ATP-sulfurylase PF01747.17 EGB10351.1 - 1.4e-65 220.8 0.0 3.3e-65 219.5 0.0 1.6 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EGB10351.1 - 1.1e-39 135.6 0.0 2.2e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_12 PF13087.6 EGB10352.1 - 1.2e-33 116.4 0.0 1.8e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGB10352.1 - 2e-27 96.6 0.0 1.6e-12 47.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain FH2 PF02181.23 EGB10352.1 - 1.9e-19 70.1 0.0 3.2e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain AAA_19 PF13245.6 EGB10352.1 - 4.1e-08 33.7 0.0 4.2e-07 30.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain CCDC53 PF10152.9 EGB10352.1 - 5e-08 33.5 0.7 1.4e-07 32.1 0.2 1.8 1 1 0 1 1 1 1 Subunit CCDC53 of WASH complex DUF2075 PF09848.9 EGB10352.1 - 0.0041 16.4 0.1 0.083 12.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGB10352.1 - 0.022 15.0 0.9 1.9 8.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EGB10352.1 - 0.028 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD-helicase PF00580.21 EGB10352.1 - 0.067 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain CSD PF00313.22 EGB10352.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Drf_FH3 PF06367.16 EGB10352.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain DnaB_C PF03796.15 EGB10352.1 - 0.081 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PhoH PF02562.16 EGB10352.1 - 0.083 12.3 0.2 0.35 10.3 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 EGB10352.1 - 0.11 12.9 0.1 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HMG_box PF00505.19 EGB10353.1 - 6.2e-17 61.8 0.9 7.5e-17 61.5 0.9 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB10353.1 - 4.8e-15 55.9 2.2 5.6e-15 55.7 2.2 1.1 1 0 0 1 1 1 1 HMG-box domain HTH_38 PF13936.6 EGB10353.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Cyclin_N2 PF16500.5 EGB10353.1 - 0.099 13.4 0.1 0.13 13.0 0.1 1.3 1 1 0 1 1 1 0 N-terminal region of cyclin_N Ras PF00071.22 EGB10354.1 - 5.8e-56 188.6 0.0 6.7e-56 188.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB10354.1 - 1.7e-32 112.1 0.0 2.3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB10354.1 - 3.9e-11 42.7 0.0 5.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB10354.1 - 1.1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGB10354.1 - 1.6e-05 24.4 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGB10354.1 - 0.00053 19.6 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB10354.1 - 0.0013 18.6 0.1 0.79 9.6 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGB10354.1 - 0.011 16.0 0.0 0.033 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 EGB10354.1 - 0.054 12.7 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.15 EGB10354.1 - 0.055 13.5 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Aldolase_II PF00596.21 EGB10355.1 - 1.1e-40 139.5 0.1 1.5e-40 139.2 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ank_2 PF12796.7 EGB10356.1 - 1.4e-24 86.5 2.4 1.1e-12 48.3 0.2 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10356.1 - 1.2e-16 60.8 1.0 2e-06 28.2 0.1 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10356.1 - 4.4e-11 42.0 0.0 0.026 15.0 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB10356.1 - 5.9e-10 39.2 2.4 6.9e-05 23.1 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB10356.1 - 4.1e-08 33.3 0.2 0.02 15.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Oleosin PF01277.17 EGB10356.1 - 0.15 11.8 0.3 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 Oleosin Helicase_C PF00271.31 EGB10357.1 - 4.5e-12 46.3 0.0 8.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EGB10357.1 - 0.011 16.0 1.6 0.016 15.5 0.1 2.0 2 0 0 2 2 2 0 Helicase associated domain (HA2) Methyltransf_23 PF13489.6 EGB10358.1 - 5.5e-15 55.6 0.0 8.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB10358.1 - 2.9e-11 43.4 0.0 5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB10358.1 - 3.7e-09 36.3 0.0 5.6e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EGB10358.1 - 4.8e-09 36.8 0.0 9.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB10358.1 - 1.2e-08 35.5 0.0 3.2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10358.1 - 1.2e-06 29.2 0.0 4.4e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 EGB10358.1 - 0.00054 19.9 0.0 0.00099 19.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_15 PF09445.10 EGB10358.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 EGB10358.1 - 0.0027 17.7 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EGB10358.1 - 0.009 15.6 0.4 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 FtsJ PF01728.19 EGB10358.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EGB10358.1 - 0.04 13.5 0.1 0.071 12.7 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 EGB10358.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.6 1 1 0 1 1 1 0 DREV methyltransferase Peptidase_S9 PF00326.21 EGB10359.1 - 4.2e-35 121.1 0.2 1.2e-34 119.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EGB10359.1 - 5.6e-06 25.4 0.0 0.0013 17.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Mago_nashi PF02792.14 EGB10360.1 - 2.7e-76 254.5 0.1 3e-76 254.3 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein GST_C PF00043.25 EGB10361.1 - 5.1e-09 36.2 0.0 9.7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB10361.1 - 3.2e-08 33.5 0.1 7.1e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGB10361.1 - 2.6e-06 27.5 0.0 4.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB10361.1 - 4.3e-05 23.8 0.0 7.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGB10361.1 - 0.0004 20.7 0.0 0.00074 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGB10361.1 - 0.00052 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGB10361.1 - 0.00088 19.5 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NTP_transf_2 PF01909.23 EGB10362.1 - 0.00065 19.9 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain G-alpha PF00503.20 EGB10363.1 - 2.2e-94 316.5 5.1 2.7e-94 316.2 5.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGB10363.1 - 5.8e-15 55.2 1.3 4.7e-11 42.4 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB10363.1 - 0.00017 21.0 3.9 0.0072 15.7 0.3 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGB10363.1 - 0.0048 17.1 1.0 3.8 7.8 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGB10363.1 - 0.036 14.1 0.1 9.2 6.4 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EGB10363.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_C97 PF05903.14 EGB10364.1 - 7.5e-17 61.5 0.0 3e-16 59.6 0.0 1.7 1 1 0 1 1 1 1 PPPDE putative peptidase domain HNH_4 PF13395.6 EGB10365.1 - 0.18 11.7 0.1 0.51 10.3 0.1 1.8 1 1 0 1 1 1 0 HNH endonuclease G-patch PF01585.23 EGB10366.1 - 1.9e-13 50.0 8.6 4.8e-13 48.8 8.6 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGB10366.1 - 6.9e-07 29.3 3.0 6.9e-07 29.3 3.0 3.0 3 1 0 3 3 3 1 G-patch domain DUF3381 PF11861.8 EGB10366.1 - 3.6 7.4 21.5 0.48 10.2 15.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Chorion_2 PF03964.15 EGB10367.1 - 0.75 10.7 6.2 1.7 9.5 2.0 2.7 2 0 0 2 2 2 0 Chorion family 2 FAM176 PF14851.6 EGB10367.1 - 8.6 6.0 11.8 16 5.1 7.0 2.3 2 0 0 2 2 2 0 FAM176 family Pkinase PF00069.25 EGB10368.1 - 2e-51 174.9 0.0 2.2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10368.1 - 7.4e-25 87.7 0.0 1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB10368.1 - 1.3e-05 25.2 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB10368.1 - 0.00012 21.5 0.0 0.00017 21.0 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB10368.1 - 0.00045 19.6 0.0 0.045 13.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EGB10368.1 - 0.017 14.8 0.0 0.035 13.7 0.0 1.4 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 EGB10368.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGB10368.1 - 0.14 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Rod_cone_degen PF15201.6 EGB10369.1 - 0.031 14.4 1.0 16 5.7 0.1 3.0 1 1 1 3 3 3 0 Progressive rod-cone degeneration zf-UBP PF02148.19 EGB10370.1 - 1.8e-17 63.4 1.0 3.6e-17 62.4 1.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein TMF_DNA_bd PF12329.8 EGB10370.1 - 0.13 12.2 2.0 0.4 10.7 0.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 EGB10370.1 - 1.1 8.0 15.8 0.91 8.3 1.6 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein Lzipper-MIP1 PF14389.6 EGB10370.1 - 1.7 9.0 7.7 3.5 8.0 0.6 3.1 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 U-box PF04564.15 EGB10371.1 - 4.1e-08 33.3 0.0 8.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain Nucleotid_trans PF03407.16 EGB10371.1 - 0.0053 16.8 0.0 0.0082 16.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 EGB10371.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Peptidase_S15 PF02129.18 EGB10372.1 - 3.3 7.2 13.6 0.22 11.1 7.5 2.0 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Myb_DNA-binding PF00249.31 EGB10373.1 - 1.8e-15 56.9 0.2 2.4e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB10373.1 - 0.0031 17.7 0.0 0.0045 17.2 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB10373.1 - 0.0053 16.6 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 Myb DNA-binding like UCH PF00443.29 EGB10374.1 - 7.4e-32 110.8 0.0 1.1e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EGB10374.1 - 2e-21 75.5 0.4 6.3e-10 38.8 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EGB10374.1 - 1.3e-10 40.8 0.0 2.7e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Variant UBP zinc finger zf-UBP PF02148.19 EGB10374.1 - 5.2e-07 29.9 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGB10374.1 - 3e-05 23.8 0.0 0.00019 21.2 0.0 2.1 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_5 PF16577.5 EGB10374.1 - 0.071 13.3 0.0 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 UBA domain DNA_ligase_A_M PF01068.21 EGB10375.1 - 6.4e-50 169.6 0.0 9.2e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGB10375.1 - 4.8e-36 124.7 0.0 9.2e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGB10375.1 - 8.8e-24 84.0 0.0 2.9e-23 82.3 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 EGB10375.1 - 0.23 11.5 0.8 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 DNA ligase OB-like domain Sep15_SelM PF08806.11 EGB10376.1 - 1e-22 80.0 0.0 1.6e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Sep15/SelM redox domain CHAT PF12770.7 EGB10377.1 - 5.5e-09 35.9 2.2 1.2e-08 34.7 2.2 1.5 1 0 0 1 1 1 1 CHAT domain eIF3_subunit PF08597.10 EGB10377.1 - 1.3 8.8 39.5 4.2 7.2 23.8 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit PG_binding_2 PF08823.11 EGB10378.1 - 0.18 12.1 0.1 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Peptidase_S49_N PF08496.10 EGB10379.1 - 0.083 13.0 1.5 0.13 12.3 1.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Agouti PF05039.12 EGB10379.1 - 0.76 10.5 11.2 1.6 9.5 11.2 1.5 1 0 0 1 1 1 0 Agouti protein SR-25 PF10500.9 EGB10379.1 - 1.5 8.4 12.0 2.9 7.5 12.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Keratin_B2_2 PF13885.6 EGB10379.1 - 2.5 8.1 14.4 5.2 7.1 14.4 1.4 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein DUF3464 PF11947.8 EGB10379.1 - 2.7 7.7 5.7 5.3 6.8 5.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Proteasome PF00227.26 EGB10380.1 - 3.1e-38 131.2 0.0 4.5e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit HMG_box PF00505.19 EGB10380.1 - 1.3e-25 89.6 0.4 2.4e-15 56.7 0.1 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB10380.1 - 3.9e-15 56.2 2.1 1.4e-09 38.4 0.2 2.4 2 0 0 2 2 2 2 HMG-box domain fn3 PF00041.21 EGB10380.1 - 0.00016 21.9 0.1 0.00028 21.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain IF-2 PF11987.8 EGB10382.1 - 3.4 7.8 46.8 4.6 7.4 1.6 9.2 3 3 6 10 10 10 0 Translation-initiation factor 2 RRM_1 PF00076.22 EGB10383.1 - 5.1e-17 61.5 0.0 8.1e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGB10383.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGB10383.1 - 0.18 11.9 0.0 0.85 9.8 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif Dynamin_N PF00350.23 EGB10384.1 - 7.3e-38 130.2 0.0 9.6e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB10384.1 - 3.7e-07 30.2 0.0 7.2e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 EGB10384.1 - 1.8e-06 27.4 0.0 2.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region AAA_21 PF13304.6 EGB10384.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 EGB10384.1 - 0.1 12.1 0.0 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 EGB10384.1 - 0.15 12.5 2.7 1.6 9.1 2.7 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EGB10384.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ASCH PF04266.14 EGB10385.1 - 0.001 19.6 0.3 0.0031 18.1 0.1 1.9 2 1 0 2 2 2 1 ASCH domain Carboxyl_trans PF01039.22 EGB10386.1 - 1.1e-128 430.0 0.1 2.4e-128 428.9 0.1 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain GNAT_acetyltr_2 PF13718.6 EGB10386.1 - 5.1e-83 277.9 0.0 9.2e-83 277.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 CPSase_L_D2 PF02786.17 EGB10386.1 - 7.7e-59 198.7 0.0 1.7e-58 197.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Helicase_RecD PF05127.14 EGB10386.1 - 1.3e-51 174.9 0.1 2.8e-51 173.9 0.1 1.6 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 EGB10386.1 - 1.3e-44 152.7 0.0 3.3e-44 151.3 0.0 1.7 1 0 0 1 1 1 1 Possible tRNA binding domain Biotin_carb_N PF00289.22 EGB10386.1 - 1.9e-34 118.5 0.4 6e-34 116.9 0.4 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain DUF1726 PF08351.11 EGB10386.1 - 4.2e-28 97.1 0.0 9.7e-28 96.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Biotin_lipoyl PF00364.22 EGB10386.1 - 1.1e-13 50.8 0.2 2.3e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_carb_C PF02785.19 EGB10386.1 - 4.7e-13 49.2 0.0 9.9e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain VIT1 PF01988.19 EGB10386.1 - 2e-09 37.6 0.4 2e-09 37.6 0.4 2.0 2 0 0 2 2 2 1 VIT family ATP-grasp PF02222.22 EGB10386.1 - 1e-05 25.2 0.0 7.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGB10386.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus AAA_22 PF13401.6 EGB10386.1 - 0.01 16.1 0.0 0.044 14.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Biotin_lipoyl_2 PF13533.6 EGB10386.1 - 0.011 15.6 5.2 1.1 9.2 0.8 3.0 1 1 1 2 2 2 0 Biotin-lipoyl like DUF3676 PF12429.8 EGB10386.1 - 0.021 14.6 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) DUF1499 PF07386.11 EGB10386.1 - 0.073 13.6 0.1 0.27 11.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) LTXXQ PF07813.12 EGB10386.1 - 0.084 13.6 0.2 0.4 11.4 0.2 2.3 1 0 0 1 1 1 0 LTXXQ motif family protein Acetyltransf_1 PF00583.25 EGB10386.1 - 0.16 12.2 0.0 0.47 10.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CDC45 PF02724.14 EGB10386.1 - 1.5 7.0 3.8 2.2 6.5 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Acyl_transf_3 PF01757.22 EGB10387.1 - 2.4e-22 79.5 26.0 4.3e-22 78.6 26.0 1.4 1 0 0 1 1 1 1 Acyltransferase family Methyltransf_25 PF13649.6 EGB10387.1 - 6.7e-09 36.3 0.2 1.9e-08 34.9 0.1 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB10387.1 - 2e-06 28.4 0.1 4.9e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB10387.1 - 2.6e-06 27.1 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGB10387.1 - 0.00013 21.5 0.1 0.00022 20.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EGB10387.1 - 0.00039 21.1 0.0 0.001 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB10387.1 - 0.00098 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB10387.1 - 0.0096 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EGB10387.1 - 0.026 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF43 PF01861.16 EGB10387.1 - 0.045 13.0 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_16 PF10294.9 EGB10387.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase STT3 PF02516.14 EGB10388.1 - 1.3e-52 179.4 7.0 6.5e-48 163.9 6.6 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Mito_carr PF00153.27 EGB10389.1 - 8.3e-56 185.9 1.4 2.5e-20 72.2 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.7 EGB10390.1 - 5.4e-27 94.2 5.4 9.6e-14 51.7 0.6 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10390.1 - 2.2e-24 85.5 3.4 7.7e-10 39.1 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB10390.1 - 2.5e-18 65.9 8.0 2.6e-09 37.2 0.3 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB10390.1 - 4.7e-16 58.4 9.3 1.5e-07 31.5 0.4 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EGB10390.1 - 4.4e-11 42.0 4.4 0.021 15.3 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ion_trans PF00520.31 EGB10391.1 - 3.1e-09 36.4 0.8 3.1e-09 36.4 0.8 1.9 3 0 0 3 3 3 1 Ion transport protein Guanylate_cyc PF00211.20 EGB10391.1 - 1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ATP_bind_1 PF03029.17 EGB10392.1 - 7.7e-59 199.4 0.0 8.7e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 EGB10392.1 - 0.00016 21.7 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 EGB10392.1 - 0.0029 17.6 0.0 0.025 14.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGB10392.1 - 0.0045 17.3 0.0 0.028 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EGB10392.1 - 0.0045 16.8 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 EGB10392.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EGB10392.1 - 0.016 15.4 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB10392.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB10392.1 - 0.066 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EGB10392.1 - 0.067 13.6 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGB10392.1 - 0.074 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EGB10392.1 - 0.081 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 EGB10392.1 - 0.086 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGB10392.1 - 0.14 11.8 0.0 0.93 9.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EGB10392.1 - 0.14 12.5 0.2 0.28 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Ploopntkinase3 PF18751.1 EGB10392.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 EGB10392.1 - 0.24 11.9 0.0 0.47 11.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DNA_primase_S PF01896.19 EGB10393.1 - 2.5e-51 174.2 0.0 4.5e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit Peptidase_S10 PF00450.22 EGB10394.1 - 2.4e-61 208.4 0.0 2.9e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 EGB10395.1 - 2.7e-32 112.7 0.0 3e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase YchF-GTPase_C PF06071.13 EGB10396.1 - 5.7e-35 119.4 1.2 8.6e-35 118.8 0.1 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGB10396.1 - 1.5e-21 76.6 0.0 3.9e-21 75.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB10396.1 - 7.7e-08 32.0 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B CYTL1 PF15153.6 EGB10396.1 - 0.06 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Cytokine-like protein 1 Ephrin_rec_like PF07699.13 EGB10397.1 - 2.2e-06 27.3 80.1 0.00054 19.7 0.9 8.1 6 1 1 8 8 8 5 Putative ephrin-receptor like TRP PF06011.12 EGB10397.1 - 0.37 9.4 5.0 0.072 11.8 1.2 1.6 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel PetG PF02529.15 EGB10397.1 - 1.8 8.5 3.6 4.6 7.2 3.6 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF667 PF05018.13 EGB10399.1 - 8.6e-15 54.9 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) RabGAP-TBC PF00566.18 EGB10399.1 - 3.2e-08 33.5 0.0 5.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mem_trans PF03547.18 EGB10400.1 - 3e-19 68.7 6.9 8.8e-11 40.8 6.7 3.0 3 0 0 3 3 3 3 Membrane transport protein Sulfatase PF00884.23 EGB10401.1 - 2.5e-63 214.3 0.2 3.6e-63 213.8 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB10401.1 - 1.1e-05 25.2 0.4 0.00014 21.6 0.1 2.5 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 EGB10401.1 - 0.0077 16.1 0.0 0.029 14.3 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function Sulfatase_C PF14707.6 EGB10401.1 - 0.0095 16.7 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Methyltransf_25 PF13649.6 EGB10402.1 - 5.5e-10 39.8 0.7 3.5e-09 37.3 0.1 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB10402.1 - 9.7e-08 32.6 0.5 3.1e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGB10402.1 - 2e-07 30.7 0.2 3.1e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB10402.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGB10402.1 - 1.8e-05 24.6 0.0 3.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB10402.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 EGB10402.1 - 0.00048 20.0 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 EGB10402.1 - 0.0039 17.0 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGB10402.1 - 0.0048 17.0 0.0 0.0071 16.5 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PRMT5_C PF17286.2 EGB10402.1 - 0.008 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 EGB10402.1 - 0.015 15.0 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.12 EGB10402.1 - 0.018 15.8 0.0 0.085 13.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGB10402.1 - 0.023 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB10402.1 - 0.032 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 EGB10402.1 - 0.035 13.0 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DREV PF05219.12 EGB10402.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase EMP24_GP25L PF01105.24 EGB10403.1 - 5e-21 75.5 0.0 1.6e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD MFS_1 PF07690.16 EGB10403.1 - 8.2e-17 61.2 32.4 6e-12 45.2 17.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol_A_exo1 PF01612.20 EGB10403.1 - 1e-15 57.9 0.0 2.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Ank_2 PF12796.7 EGB10403.1 - 2.9e-11 43.8 1.9 3.9e-06 27.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10403.1 - 9.2e-11 42.1 4.9 9.7e-10 38.8 0.1 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB10403.1 - 4.3e-08 33.2 1.9 0.023 15.1 0.0 4.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EGB10403.1 - 1e-06 28.6 3.5 1.4 9.7 0.2 5.2 4 0 0 4 4 4 2 Ankyrin repeat R3H PF01424.22 EGB10403.1 - 1e-06 28.6 0.0 1e-06 28.6 0.0 3.0 3 0 0 3 3 3 1 R3H domain Ank_5 PF13857.6 EGB10403.1 - 0.014 15.7 3.5 0.11 12.8 0.0 3.9 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Mito_fiss_reg PF05308.11 EGB10403.1 - 4.9 7.2 15.7 62 3.5 12.2 3.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4464 PF14713.6 EGB10404.1 - 3.7e-96 321.0 0.9 4.2e-96 320.8 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Lectin_C PF00059.21 EGB10405.1 - 1.9e-58 195.9 5.2 6.2e-12 46.2 0.0 7.6 6 1 0 6 6 6 6 Lectin C-type domain G8 PF10162.9 EGB10405.1 - 0.074 13.1 0.1 35 4.5 0.0 3.3 2 1 1 3 3 3 0 G8 domain UL45 PF05473.12 EGB10405.1 - 0.1 12.2 3.3 0.95 9.1 0.1 2.9 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like PRA-CH PF01502.18 EGB10406.1 - 4.8e-23 80.8 0.1 5.9e-23 80.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase FKBP_C PF00254.28 EGB10407.1 - 8.9e-21 74.0 0.0 1.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 EGB10407.1 - 3.6e-05 24.6 0.3 9.5e-05 23.3 0.2 1.7 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2895 PF11444.8 EGB10407.1 - 0.21 11.0 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) SNF2_N PF00176.23 EGB10408.1 - 5e-70 235.9 0.0 1.6e-69 234.3 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB10408.1 - 2.6e-20 72.8 0.0 6e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB10408.1 - 1.4e-11 44.7 0.0 2.2e-10 40.8 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGB10408.1 - 4.2e-07 29.4 0.0 8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EGB10408.1 - 4.3e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGB10408.1 - 0.00029 20.6 0.0 0.0018 18.0 0.0 2.2 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EGB10408.1 - 0.003 16.8 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DBINO PF13892.6 EGB10408.1 - 0.0039 17.5 1.3 0.0039 17.5 1.3 2.0 2 0 0 2 2 2 1 DNA-binding domain Sulfotransfer_1 PF00685.27 EGB10410.1 - 1.4e-47 162.4 0.0 5.7e-38 130.9 0.0 2.0 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB10410.1 - 4e-08 33.9 0.0 5.8e-06 26.9 0.0 2.2 1 1 0 2 2 2 2 Sulfotransferase family Got1 PF04178.12 EGB10411.1 - 5e-11 43.0 10.3 7.1e-11 42.5 10.3 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 EGB10411.1 - 0.0031 17.8 6.7 0.0031 17.8 6.7 2.2 1 1 1 2 2 2 1 Short repeat of unknown function (DUF308) DUF2157 PF09925.9 EGB10411.1 - 4.9 6.9 9.5 7.1 6.4 9.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) AMP-binding PF00501.28 EGB10412.1 - 8.6e-70 235.4 0.0 2e-69 234.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGB10412.1 - 3e-06 27.5 0.0 6.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGB10412.1 - 0.00018 22.4 3.5 0.00038 21.4 0.1 3.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain VWA PF00092.28 EGB10412.1 - 0.005 17.1 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EGB10412.1 - 0.12 12.4 0.0 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 vWA found in TerF C terminus Mucin PF01456.17 EGB10412.1 - 8.9 6.3 28.3 0.016 15.2 12.5 3.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Myb_DNA-binding PF00249.31 EGB10413.1 - 4.1e-30 103.7 7.2 1.5e-13 50.7 0.2 3.0 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB10413.1 - 2.2e-26 91.8 1.5 6e-15 55.3 0.1 3.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGB10413.1 - 0.00032 20.7 0.0 0.14 12.2 0.0 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EGB10413.1 - 0.002 18.0 0.0 0.012 15.4 0.0 1.9 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EGB10413.1 - 0.0021 18.2 0.0 0.58 10.4 0.0 2.2 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EGB10413.1 - 0.0025 17.8 0.5 0.051 13.7 0.5 2.2 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 EGB10413.1 - 0.0044 17.1 0.4 1.1 9.4 0.0 2.7 1 1 2 3 3 3 1 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_2 PF08914.11 EGB10413.1 - 0.0044 17.2 0.2 0.29 11.4 0.1 2.9 1 1 1 2 2 2 1 Rap1 Myb domain DUF4211 PF13926.6 EGB10413.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) Myb_DNA-bind_4 PF13837.6 EGB10413.1 - 2.3 8.7 5.7 20 5.6 0.2 3.5 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain LCAT PF02450.15 EGB10414.1 - 1.4e-65 222.0 0.0 9.8e-65 219.2 0.0 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 EGB10414.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGB10414.1 - 0.033 14.8 18.5 0.089 13.4 18.5 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EGB10414.1 - 0.036 14.2 0.0 4.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Hydrolase_4 PF12146.8 EGB10414.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ribosomal_L27A PF00828.19 EGB10415.1 - 3.7e-14 53.5 0.0 4e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 EGB10416.1 - 4.1e-41 141.1 0.0 7.1e-41 140.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10416.1 - 5.5e-18 65.2 0.0 7.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB10416.1 - 7.6e-08 32.6 3.8 5.6e-05 23.2 1.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EGB10416.1 - 0.00063 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGB10416.1 - 0.00069 19.0 0.2 0.0013 18.1 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB10416.1 - 0.0011 18.4 0.0 0.0038 16.6 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB10416.1 - 0.017 13.9 0.0 0.05 12.4 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 EGB10416.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Arm PF00514.23 EGB10417.1 - 8.5e-08 32.0 0.1 2.4e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat WD40 PF00400.32 EGB10417.1 - 0.00018 22.2 15.6 0.24 12.4 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT_EZ PF13513.6 EGB10417.1 - 0.0048 17.4 1.8 0.017 15.6 0.1 2.9 2 0 0 2 2 2 1 HEAT-like repeat Sugarporin_N PF11471.8 EGB10417.1 - 0.0094 15.9 2.0 0.0094 15.9 2.0 2.4 3 0 0 3 3 3 1 Maltoporin periplasmic N-terminal extension HEAT PF02985.22 EGB10417.1 - 0.099 12.9 0.6 0.51 10.7 0.1 2.5 2 0 0 2 2 2 0 HEAT repeat DivIC PF04977.15 EGB10417.1 - 0.32 10.8 3.4 3.6 7.4 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF333 PF03891.15 EGB10417.1 - 1.4 9.1 4.0 1.4 9.1 0.2 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF333) Pkinase PF00069.25 EGB10418.1 - 1.3e-52 178.8 0.0 1.5e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10418.1 - 8.7e-35 120.2 0.0 1.1e-34 119.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB10418.1 - 5.3e-05 22.2 0.0 7.8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB10418.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB10418.1 - 0.019 14.9 0.4 0.047 13.6 0.4 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB10418.1 - 0.1 11.9 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 EGB10418.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_M16 PF00675.20 EGB10419.1 - 1.8e-07 31.2 0.0 3.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGB10419.1 - 0.0091 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Pkinase PF00069.25 EGB10420.1 - 1.6e-67 227.7 0.0 2e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10420.1 - 1.6e-29 103.0 0.0 2.1e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB10420.1 - 8.8e-07 28.5 0.0 8.6e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_C PF00433.24 EGB10420.1 - 2.3e-05 25.0 0.5 4.8e-05 24.0 0.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGB10420.1 - 0.03 13.3 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain LBR_tudor PF09465.10 EGB10421.1 - 3.3e-05 23.6 0.0 9.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 EGB10421.1 - 0.00015 21.6 0.1 0.00027 20.7 0.1 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain zf-RING_2 PF13639.6 EGB10421.1 - 0.00017 21.9 11.2 0.00017 21.9 11.2 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGB10421.1 - 0.00037 20.3 8.6 0.00037 20.3 8.6 2.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Agenet PF05641.12 EGB10421.1 - 0.031 14.7 0.1 0.065 13.7 0.1 1.5 1 0 0 1 1 1 0 Agenet domain Tudor_2 PF18104.1 EGB10421.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain SNF2_N PF00176.23 EGB10422.1 - 4.4e-52 176.9 0.0 1.4e-51 175.3 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB10422.1 - 5e-16 59.0 0.0 8.6e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EGB10422.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 STI1 PF17830.1 EGB10423.1 - 0.0032 17.4 4.3 0.26 11.3 0.0 2.5 2 0 0 2 2 2 2 STI1 domain Nuc_N PF14448.6 EGB10423.1 - 0.014 15.2 7.0 16 5.5 0.1 5.3 6 0 0 6 6 6 0 Nuclease N terminal UCH PF00443.29 EGB10423.1 - 0.035 13.6 0.0 4.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase T2SSF PF00482.23 EGB10423.1 - 0.087 12.8 16.9 9.4 6.2 0.3 6.3 5 0 0 5 5 5 0 Type II secretion system (T2SS), protein F Muted PF14942.6 EGB10423.1 - 0.17 12.3 0.9 25 5.2 0.1 3.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Arm PF00514.23 EGB10424.1 - 9.1e-98 317.7 30.9 1.8e-10 40.5 0.1 10.0 10 0 0 10 10 10 10 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EGB10424.1 - 8.3e-12 45.0 0.5 0.83 9.7 0.0 6.5 5 2 1 7 7 7 4 Spinocerebellar ataxia type 10 protein domain CRS1_YhbY PF01985.21 EGB10424.1 - 6.8e-08 32.6 0.2 4.3 7.6 0.0 7.8 9 0 0 9 9 9 1 CRS1 / YhbY (CRM) domain CENP-P PF13096.6 EGB10424.1 - 9.1e-06 25.5 0.9 44 3.7 0.0 7.1 5 2 3 8 8 8 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Arm_2 PF04826.13 EGB10424.1 - 5.2e-05 22.8 0.1 3.5 7.0 0.0 4.3 1 1 2 3 3 3 2 Armadillo-like Aconitase_B_N PF11791.8 EGB10424.1 - 9.9e-05 22.4 10.0 39 4.3 0.1 7.8 1 1 4 7 7 7 0 Aconitate B N-terminal domain Adaptin_N PF01602.20 EGB10424.1 - 0.00065 18.4 0.0 16 3.9 0.0 4.5 2 1 2 5 5 5 1 Adaptin N terminal region N_formyltrans_C PF18216.1 EGB10424.1 - 0.064 12.9 0.8 1.2e+02 2.4 0.0 5.7 8 0 0 8 8 8 0 N-formyltransferase dimerization C-terminal domain DUF3954 PF13128.6 EGB10424.1 - 0.27 11.1 0.9 29 4.6 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3954) HEAT_EZ PF13513.6 EGB10424.1 - 0.47 11.0 42.1 1.1 9.9 1.3 7.1 3 3 5 8 8 8 0 HEAT-like repeat DER1 PF04511.15 EGB10425.1 - 1.6e-23 83.6 1.8 1.7e-23 83.6 1.8 1.0 1 0 0 1 1 1 1 Der1-like family HSP70 PF00012.20 EGB10427.1 - 3.9e-256 851.0 7.5 4.6e-256 850.8 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGB10427.1 - 3e-13 49.3 1.0 5.1e-11 42.0 0.1 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EGB10427.1 - 0.0054 17.1 3.9 3.6 8.1 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA GFRP PF06399.13 EGB10427.1 - 0.0087 15.9 0.0 0.036 14.0 0.0 2.0 2 0 0 2 2 2 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) FlxA PF14282.6 EGB10427.1 - 7.9 6.5 10.8 0.36 10.8 3.9 2.4 2 1 0 2 2 2 0 FlxA-like protein zf-Tim10_DDP PF02953.15 EGB10428.1 - 1.5e-16 59.8 4.0 1.8e-16 59.5 4.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RNase_P_Rpp14 PF01900.19 EGB10428.1 - 0.087 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Rpp14/Pop5 family DUF4391 PF14335.6 EGB10428.1 - 0.096 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) CLAMP PF14769.6 EGB10430.1 - 7.1e-31 106.6 0.2 1.4e-30 105.7 0.2 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 bZIP_1 PF00170.21 EGB10430.1 - 0.00023 21.2 13.2 0.00023 21.2 13.2 2.0 2 0 0 2 2 2 1 bZIP transcription factor FpoO PF10621.9 EGB10430.1 - 0.013 15.8 0.4 0.068 13.5 0.1 2.1 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO CDC45 PF02724.14 EGB10430.1 - 0.3 9.3 12.0 0.59 8.4 12.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Mpv17_PMP22 PF04117.12 EGB10431.1 - 1.2e-07 31.9 1.7 2.8e-07 30.7 1.7 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family PDZ_6 PF17820.1 EGB10431.1 - 1e-06 28.4 0.2 0.0013 18.6 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EGB10431.1 - 0.0021 18.4 0.0 0.58 10.5 0.0 2.6 2 0 0 2 2 2 1 PDZ domain bZIP_2 PF07716.15 EGB10431.1 - 0.013 15.6 16.7 0.013 15.6 16.7 2.1 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 EGB10431.1 - 0.12 12.5 15.2 0.34 11.0 15.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor HAUS-augmin3 PF14932.6 EGB10431.1 - 1.3 8.5 4.7 2.1 7.9 4.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Pox_G5 PF04599.12 EGB10431.1 - 8.7 5.2 9.2 13 4.6 9.2 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Amidohydro_1 PF01979.20 EGB10432.1 - 8.8e-11 41.7 0.0 9.4e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGB10432.1 - 3.2e-07 30.2 0.1 4.2e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family XdhC_CoxI PF02625.16 EGB10432.1 - 0.041 14.1 1.7 0.045 13.9 0.2 1.9 2 0 0 2 2 2 0 XdhC and CoxI family LSM PF01423.22 EGB10433.1 - 7.2e-19 67.2 0.0 9e-19 66.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGB10433.1 - 0.032 14.4 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain CoaE PF01121.20 EGB10434.1 - 6.6e-35 120.4 0.0 8e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase dNK PF01712.19 EGB10434.1 - 0.038 13.8 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase 4HBT PF03061.22 EGB10435.1 - 2.6e-14 53.3 0.8 3e-14 53.1 0.8 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGB10435.1 - 0.00011 22.5 1.1 0.00012 22.4 1.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Choline_kinase PF01633.20 EGB10436.1 - 1.2e-06 28.2 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase TM231 PF10149.9 EGB10437.1 - 1.9e-90 303.3 0.0 2.1e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 MOSC_N PF03476.16 EGB10439.1 - 1.3e-27 96.1 0.0 3.1e-27 94.8 0.0 1.6 1 1 1 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EGB10439.1 - 1.7e-06 28.1 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Ral PF11058.8 EGB10439.1 - 0.014 14.9 0.6 0.077 12.6 0.2 2.2 2 0 0 2 2 2 0 Antirestriction protein Ral DUF3357 PF11837.8 EGB10440.1 - 0.22 12.0 1.0 0.49 10.9 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Ank_2 PF12796.7 EGB10441.1 - 2.9e-22 79.0 0.1 3.8e-11 43.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10441.1 - 3.5e-21 75.3 0.1 2.6e-10 40.6 0.0 3.1 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB10441.1 - 1.3e-12 47.7 0.4 3.7e-10 39.9 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10441.1 - 1.1e-10 40.8 0.1 0.00071 19.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGB10441.1 - 5e-10 39.4 3.5 1.7e-05 25.1 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeat Acyl_transf_1 PF00698.21 EGB10442.1 - 9.9e-22 77.8 0.1 1.9e-21 76.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.20 EGB10442.1 - 3.8e-11 43.5 0.0 6.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGB10442.1 - 0.0012 19.5 1.9 0.0017 19.0 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DEC-1_N PF04625.13 EGB10442.1 - 1.1 8.2 9.8 2.1 7.3 9.8 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peptidase_M24 PF00557.24 EGB10443.1 - 2.8e-38 131.7 0.0 5e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EGB10443.1 - 1.6e-32 112.9 0.0 2.7e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 EGB10443.1 - 5e-19 69.3 0.0 1.6e-18 67.6 0.0 1.8 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGB10443.1 - 3.9e-17 62.1 0.4 1.5e-16 60.2 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Pkinase PF00069.25 EGB10444.1 - 4.9e-27 95.0 0.0 7.3e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10444.1 - 7.2e-10 38.6 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ELMO_CED12 PF04727.13 EGB10445.1 - 1e-25 90.9 0.0 1.4e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family WW PF00397.26 EGB10445.1 - 1.1e-08 35.0 2.2 0.00051 20.1 0.1 2.9 2 0 0 2 2 2 2 WW domain PH PF00169.29 EGB10445.1 - 4.3e-06 27.2 0.0 9.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 PH domain DUF3168 PF11367.8 EGB10445.1 - 0.71 10.1 6.3 3.7 7.8 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3168) Trypan_PARP PF05887.11 EGB10446.1 - 0.00041 20.3 19.5 0.0018 18.2 19.5 2.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 EGB10446.1 - 2 6.8 6.4 3.3 6.1 6.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Roc PF08477.13 EGB10448.1 - 5.2e-10 39.6 0.0 7.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGB10448.1 - 6.5e-10 38.8 0.0 7.7e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EGB10448.1 - 1e-06 28.3 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB10448.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGB10448.1 - 0.0012 19.3 0.0 0.0021 18.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGB10448.1 - 0.0036 17.2 0.0 0.0086 16.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Cytidylate_kin PF02224.18 EGB10448.1 - 0.013 15.2 0.1 0.017 14.8 0.1 1.1 1 0 0 1 1 1 0 Cytidylate kinase AAA_18 PF13238.6 EGB10448.1 - 0.014 15.9 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGB10448.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB10448.1 - 0.018 15.3 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGB10448.1 - 0.026 14.7 0.0 0.075 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGB10448.1 - 0.035 14.5 0.0 0.035 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGB10448.1 - 0.054 13.2 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGB10448.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EGB10448.1 - 0.11 13.0 0.1 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGB10448.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGB10448.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF1989 PF09347.10 EGB10449.1 - 1.4e-58 197.2 0.0 1.9e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AhpC-TSA PF00578.21 EGB10450.1 - 6.5e-26 90.7 0.0 9e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGB10450.1 - 4.6e-09 36.1 0.0 6.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGB10450.1 - 0.002 17.9 0.3 0.0079 16.0 0.0 2.3 2 1 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin LSM PF01423.22 EGB10452.1 - 5.2e-16 58.1 0.2 5.7e-16 58.0 0.2 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGB10452.1 - 0.048 13.3 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Hfq protein DnaJ PF00226.31 EGB10453.1 - 5.7e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain Sel1 PF08238.12 EGB10454.1 - 1.4e-15 57.3 1.5 1.3e-10 41.6 0.3 2.1 2 0 0 2 2 2 2 Sel1 repeat Mito_carr PF00153.27 EGB10455.1 - 6.5e-43 144.6 2.2 7.2e-17 61.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COG5 PF10392.9 EGB10456.1 - 1.3e-06 28.6 0.0 4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 CENP-H PF05837.12 EGB10456.1 - 2.7 8.4 5.3 14 6.1 0.4 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4116 PF13475.6 EGB10457.1 - 3e-48 161.3 0.0 9.8e-08 31.6 0.0 8.4 3 3 6 10 10 10 9 Domain of unknown function (DUF4116) AP1AR PF15745.5 EGB10457.1 - 0.026 14.2 0.1 0.079 12.6 0.1 1.8 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein LSM PF01423.22 EGB10459.1 - 4.9e-15 55.0 0.1 4.9e-15 55.0 0.1 1.4 2 0 0 2 2 2 1 LSM domain DUF150_C PF17384.2 EGB10459.1 - 0.096 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain IBR PF01485.21 EGB10460.1 - 5.2e-19 68.2 26.0 1.4e-11 44.4 3.5 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGB10460.1 - 0.00012 21.9 1.2 0.00012 21.9 1.2 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB10460.1 - 0.00028 20.7 2.0 0.00028 20.7 2.0 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB10460.1 - 0.00043 20.5 3.2 0.00043 20.5 3.2 3.9 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EGB10460.1 - 0.00059 19.8 4.0 0.00059 19.8 4.0 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGB10460.1 - 0.00076 19.4 5.7 0.00076 19.4 5.7 3.8 2 1 1 3 3 3 1 zinc-RING finger domain RAMA PF18755.1 EGB10461.1 - 3.8e-13 49.8 0.3 1.9e-12 47.5 0.0 2.4 2 0 0 2 2 1 1 Restriction Enzyme Adenine Methylase Associated zf-PARP PF00645.18 EGB10461.1 - 7.7e-09 36.3 0.0 1.6e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RING_2 PF13639.6 EGB10461.1 - 1.8e-07 31.3 2.8 3.9e-07 30.3 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain Tudor_3 PF18115.1 EGB10461.1 - 3.7e-07 29.9 0.1 8e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 EGB10461.1 - 9.7e-06 25.3 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain zf-RING_UBOX PF13445.6 EGB10461.1 - 1e-05 25.5 0.2 2.5e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGB10461.1 - 1e-05 25.3 1.9 2.2e-05 24.2 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB10461.1 - 8.9e-05 22.4 2.1 0.00016 21.6 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGB10461.1 - 0.00027 20.7 0.9 0.00027 20.7 0.9 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGB10461.1 - 0.0016 18.6 0.8 0.0063 16.6 0.9 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING TUDOR_5 PF18359.1 EGB10461.1 - 0.0022 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 EGB10461.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain zf-C3HC4_3 PF13920.6 EGB10461.1 - 0.057 13.3 6.4 0.28 11.1 6.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rab5-bind PF09311.11 EGB10461.1 - 0.068 12.6 3.2 0.073 12.5 0.1 2.0 2 0 0 2 2 2 0 Rabaptin-like protein Tudor_2 PF18104.1 EGB10461.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain zf-RING_11 PF17123.5 EGB10461.1 - 5 7.0 6.9 0.39 10.5 1.9 1.8 2 0 0 2 2 2 0 RING-like zinc finger PLDc_2 PF13091.6 EGB10462.1 - 1.1e-19 70.7 0.0 2.2e-12 47.0 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc_3 PF13918.6 EGB10462.1 - 1.3e-13 51.0 0.1 4.3e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.22 EGB10462.1 - 2e-09 37.2 1.9 9e-06 25.7 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif LtrA PF06772.11 EGB10463.1 - 1.6e-14 53.9 24.5 2.1e-14 53.5 24.5 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) PhyH PF05721.13 EGB10463.1 - 2.2e-09 37.9 0.3 8.2e-08 32.8 0.0 2.8 3 0 0 3 3 3 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 EGB10463.1 - 4.2e-05 24.4 0.0 0.013 16.4 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB10463.1 - 7.5e-05 23.2 0.0 0.00021 21.8 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1479 PF07350.12 EGB10463.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) TPR_14 PF13428.6 EGB10464.1 - 2.6e-17 62.0 57.8 1.5e-05 25.4 0.3 10.7 5 4 5 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGB10464.1 - 2.7e-10 39.9 12.5 0.0022 18.3 0.1 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB10464.1 - 4.4e-10 39.9 32.7 2.3e-06 28.0 1.9 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10464.1 - 1.1e-08 34.6 34.3 0.23 11.6 0.3 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10464.1 - 1.8e-06 27.7 6.0 4.9 7.6 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB10464.1 - 0.00025 20.6 16.1 1.7 8.4 0.1 7.1 6 1 1 7 7 7 2 TPR repeat TPR_16 PF13432.6 EGB10464.1 - 0.00085 19.9 70.7 0.001 19.7 6.9 7.5 4 3 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10464.1 - 0.022 15.1 34.1 0.23 11.7 2.4 7.5 5 4 1 6 6 6 0 Tetratricopeptide repeat Suf PF05843.14 EGB10464.1 - 0.043 13.8 0.1 9.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_1 PF00515.28 EGB10464.1 - 0.36 10.7 11.8 6.7 6.7 0.2 6.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGB10464.1 - 0.83 9.7 3.6 7.2 6.6 0.0 3.5 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_20 PF14561.6 EGB10464.1 - 1.2 9.6 6.8 2.9 8.3 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB10464.1 - 5.5 7.2 11.2 11 6.4 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Pkinase PF00069.25 EGB10465.1 - 4.7e-20 72.1 0.0 5.3e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10465.1 - 4.9e-19 68.6 0.0 5.4e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB10465.1 - 0.0011 19.0 1.6 0.0043 17.0 1.6 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB10465.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB10465.1 - 0.15 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ParcG PF10274.9 EGB10466.1 - 4e-63 212.9 0.0 4.7e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EGB10466.1 - 0.0004 20.1 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 AA_kinase PF00696.28 EGB10467.1 - 5.9e-42 143.9 0.0 1e-41 143.2 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 EGB10467.1 - 0.00015 21.5 0.8 0.15 11.9 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EGB10467.1 - 0.14 12.0 2.5 1.4 8.8 0.3 2.4 2 0 0 2 2 2 0 ACT domain CoaE PF01121.20 EGB10468.1 - 1.1e-41 142.5 0.0 1.3e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.6 EGB10468.1 - 0.03 14.6 0.0 0.084 13.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain Flavodoxin_1 PF00258.25 EGB10469.1 - 1.3e-11 44.9 0.0 2.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Ank_4 PF13637.6 EGB10469.1 - 0.01 16.4 0.0 0.034 14.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) WWE PF02825.20 EGB10469.1 - 0.014 16.0 0.0 0.046 14.3 0.0 1.9 1 0 0 1 1 1 0 WWE domain SAM_2 PF07647.17 EGB10469.1 - 0.027 14.6 0.0 0.35 11.0 0.0 2.6 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGB10469.1 - 0.059 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MazE_antitoxin PF04014.18 EGB10469.1 - 0.081 12.9 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin CYSTM PF12734.7 EGB10469.1 - 0.13 12.6 1.2 0.5 10.7 1.2 2.0 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Lectin_leg-like PF03388.13 EGB10470.1 - 1.7e-18 66.8 0.0 1.1e-17 64.2 0.0 2.1 1 1 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EGB10470.1 - 0.035 14.1 0.0 0.056 13.5 0.0 1.4 1 1 0 1 1 1 0 Bacterial lectin Peptidase_S9 PF00326.21 EGB10471.1 - 4e-06 26.5 0.1 1.2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 EGB10471.1 - 0.00035 20.1 5.1 0.0013 18.3 0.3 3.2 3 1 0 4 4 4 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 EGB10471.1 - 0.0031 17.3 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGB10471.1 - 0.096 11.9 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 EGB10471.1 - 0.15 11.7 0.2 0.27 10.8 0.0 1.5 2 0 0 2 2 2 0 Putative esterase AXE1 PF05448.12 EGB10471.1 - 0.17 10.5 0.0 0.39 9.4 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAGE PF08180.11 EGB10471.1 - 6.5 6.9 14.4 16 5.7 8.4 2.5 2 0 0 2 2 2 0 B melanoma antigen family 2OG-FeII_Oxy_3 PF13640.6 EGB10472.1 - 4.7e-09 37.0 0.0 1.6e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Acid_PPase PF12689.7 EGB10472.1 - 0.031 14.1 1.0 0.51 10.2 1.0 2.4 1 1 0 1 1 1 0 Acid Phosphatase Oxygenase-NA PF09859.9 EGB10472.1 - 0.046 13.2 0.2 0.18 11.3 0.0 1.9 1 1 1 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA Hydrolase PF00702.26 EGB10472.1 - 0.19 12.0 2.0 15 5.8 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase GST_C_3 PF14497.6 EGB10473.1 - 3.3e-12 46.5 0.0 5.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EGB10473.1 - 3.7e-07 31.0 0.0 6.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C PF00043.25 EGB10473.1 - 4.3e-07 30.1 0.0 1.2e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB10473.1 - 0.001 19.4 0.0 0.0031 17.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB10473.1 - 0.01 16.3 0.0 0.031 14.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB10473.1 - 0.011 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EF-hand_1 PF00036.32 EGB10474.1 - 3.6e-13 48.0 0.0 0.00043 19.6 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGB10474.1 - 4.4e-13 48.0 0.1 0.005 16.7 0.0 5.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EGB10474.1 - 7e-11 41.1 0.6 0.0016 17.8 0.1 4.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EGB10474.1 - 1.4e-10 41.4 0.0 0.033 14.6 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EGB10474.1 - 2.1e-09 37.1 2.2 0.34 10.8 0.0 5.2 5 1 1 6 6 6 4 EF-hand domain pair PDZ PF00595.24 EGB10474.1 - 0.013 15.9 0.0 0.064 13.6 0.0 2.1 2 0 0 2 2 2 0 PDZ domain PDZ_6 PF17820.1 EGB10474.1 - 0.077 12.8 1.4 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 PDZ domain Tubulin PF00091.25 EGB10475.1 - 2.5e-66 223.7 0.0 3.3e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB10475.1 - 1.9e-43 147.6 0.1 2.2e-37 128.0 0.0 2.9 3 0 0 3 3 3 2 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGB10475.1 - 0.00033 20.9 0.0 0.00062 20.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EGB10475.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin like tRNA_bind PF01588.20 EGB10476.1 - 2e-25 88.7 0.0 2.6e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain DnaJ_C PF01556.18 EGB10477.1 - 2.7e-22 79.5 0.0 3.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB10477.1 - 5.3e-17 61.7 0.2 9e-17 61.0 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain HPP PF04982.13 EGB10477.1 - 0.21 11.8 0.3 0.48 10.6 0.3 1.5 1 0 0 1 1 1 0 HPP family RRM_1 PF00076.22 EGB10478.1 - 1.2e-22 79.4 0.0 1.4e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGB10478.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_trans_2_3 PF13632.6 EGB10479.1 - 2e-07 31.1 6.5 3.8e-07 30.2 6.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGB10479.1 - 1e-05 25.6 3.7 7.7e-05 22.7 3.7 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF3318 PF11780.8 EGB10479.1 - 0.014 15.4 0.2 0.028 14.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Glycos_transf_2 PF00535.26 EGB10479.1 - 0.022 14.6 0.0 0.054 13.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 Ank_2 PF12796.7 EGB10480.1 - 8.5e-22 77.5 0.2 2.5e-08 34.4 0.2 4.2 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10480.1 - 1.4e-18 67.0 5.3 2.3e-06 28.0 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10480.1 - 4e-11 42.1 10.2 0.038 14.5 0.0 7.9 8 1 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 EGB10480.1 - 8.7e-10 38.6 6.8 0.12 12.9 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EGB10480.1 - 2.1e-08 34.3 11.9 0.012 15.9 0.7 6.8 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Metallophos PF00149.28 EGB10481.1 - 1.2e-27 97.7 0.1 1.6e-27 97.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGB10481.1 - 3.6e-07 30.4 0.0 6.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region DUF3499 PF12005.8 EGB10482.1 - 0.3 11.7 3.5 0.36 11.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Rhodanese PF00581.20 EGB10483.1 - 2.4e-07 31.2 0.0 5.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain RIIa PF02197.17 EGB10483.1 - 0.0044 16.7 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF5586 PF17824.1 EGB10483.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5586) EF_TS PF00889.19 EGB10484.1 - 5.7e-46 156.7 0.0 7.3e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor TS Citrate_synt PF00285.21 EGB10485.1 - 2.9e-116 388.5 0.0 3.5e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain EF-hand_1 PF00036.32 EGB10486.1 - 2.7e-09 35.9 0.4 0.00078 18.8 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB10486.1 - 4.9e-09 35.9 0.1 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB10486.1 - 1.1e-07 31.2 2.8 0.0026 17.6 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB10486.1 - 1.3e-07 30.8 1.0 0.0091 15.5 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB10486.1 - 9.1e-07 29.2 0.1 0.031 14.7 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair Ran_BP1 PF00638.18 EGB10487.1 - 3.7e-14 53.0 0.0 9.3e-14 51.7 0.0 1.6 1 1 0 1 1 1 1 RanBP1 domain PhyH PF05721.13 EGB10487.1 - 5.1e-14 53.0 0.0 1.5e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Acetyltransf_10 PF13673.7 EGB10487.1 - 3.4e-06 27.0 0.1 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB10487.1 - 0.00059 20.2 0.1 0.0039 17.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGB10487.1 - 0.0038 17.4 0.1 0.0098 16.1 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RRM_1 PF00076.22 EGB10487.1 - 0.065 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.22 EGB10487.1 - 0.18 11.7 1.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Arm PF00514.23 EGB10488.1 - 1.7e-26 91.4 21.2 2.5e-07 30.5 0.1 6.0 5 1 0 5 5 5 5 Armadillo/beta-catenin-like repeat PKD_channel PF08016.12 EGB10488.1 - 6.9e-19 67.8 13.9 8e-18 64.3 13.9 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EGB10488.1 - 4.9e-05 22.7 17.0 9.4e-05 21.8 17.0 1.4 1 0 0 1 1 1 1 Ion transport protein MAM PF00629.23 EGB10488.1 - 0.00018 21.5 1.5 0.00033 20.6 1.5 1.4 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Notch PF00066.17 EGB10488.1 - 0.00039 20.8 7.6 0.00039 20.8 7.6 3.0 2 0 0 2 2 2 1 LNR domain Atx10homo_assoc PF09759.9 EGB10488.1 - 0.013 15.5 3.9 2 8.5 0.1 2.9 2 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EGB10488.1 - 1.1 9.9 9.6 10 6.7 0.4 3.8 2 0 0 2 2 2 0 HEAT-like repeat ABC2_membrane_3 PF12698.7 EGB10488.1 - 4.5 6.3 10.7 9.3 5.2 10.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein p450 PF00067.22 EGB10489.1 - 3e-07 29.6 0.0 3.7e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_B PF00136.21 EGB10491.1 - 2.5e-139 464.9 0.0 3.1e-139 464.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGB10491.1 - 8.7e-71 238.8 0.0 1.2e-70 238.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGB10491.1 - 1.1e-17 64.2 6.2 1.1e-17 64.2 6.2 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_A_exo1 PF01612.20 EGB10491.1 - 0.028 14.1 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease DNA_pol_B_2 PF03175.13 EGB10491.1 - 0.045 12.6 0.0 0.096 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 EGB10491.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB PSP94 PF05825.11 EGB10491.1 - 0.14 12.8 2.5 0.2 12.2 0.7 2.2 2 0 0 2 2 2 0 Beta-microseminoprotein (PSP-94) NTF-like PF14540.6 EGB10491.1 - 0.18 11.5 0.0 0.75 9.6 0.0 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase-like ubiquitin PF00240.23 EGB10492.1 - 3.5e-34 116.4 1.4 5.9e-34 115.6 0.5 1.8 2 0 0 2 2 2 1 Ubiquitin family Sod_Ni PF09055.11 EGB10492.1 - 1e-27 97.2 0.0 1.8e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Rad60-SLD PF11976.8 EGB10492.1 - 6e-16 58.0 1.6 7.1e-16 57.8 0.8 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB10492.1 - 1.8e-05 25.1 0.1 6e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB10492.1 - 0.0035 17.2 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB10492.1 - 0.0081 16.3 0.0 0.031 14.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGB10492.1 - 0.012 16.0 0.1 0.028 14.8 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-like domain MobC PF05713.11 EGB10492.1 - 0.019 15.4 0.8 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) DUF2407 PF10302.9 EGB10492.1 - 0.039 14.5 0.0 0.061 13.9 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGB10492.1 - 0.097 12.7 0.8 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain BRE1 PF08647.11 EGB10493.1 - 3.8e-06 26.9 11.0 3.8e-06 26.9 11.0 8.5 5 2 3 8 8 8 1 BRE1 E3 ubiquitin ligase Atg14 PF10186.9 EGB10493.1 - 0.0053 15.9 9.2 0.0053 15.9 9.2 5.3 2 1 2 5 5 5 3 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 EGB10493.1 - 0.0076 16.4 14.1 0.0076 16.4 14.1 7.2 1 1 6 7 7 7 2 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 EGB10493.1 - 0.021 14.9 0.4 0.021 14.9 0.4 8.4 2 1 5 8 8 8 0 TPR/MLP1/MLP2-like protein AP4E_app_platf PF14807.6 EGB10493.1 - 0.3 11.5 4.5 0.35 11.2 1.9 2.5 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform DUF3138 PF11336.8 EGB10493.1 - 0.9 8.1 12.8 0.032 12.9 2.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) WD40 PF00400.32 EGB10494.1 - 4.9e-18 65.2 3.1 9e-09 35.8 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB10494.1 - 2.8e-07 30.7 0.0 0.0068 16.7 0.0 2.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pyr_redox_2 PF07992.14 EGB10495.1 - 2e-39 135.6 0.7 2.7e-39 135.2 0.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB10495.1 - 3e-21 76.0 0.0 1.6e-15 57.2 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGB10495.1 - 7.3e-16 58.5 0.8 1.4e-12 48.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGB10495.1 - 1e-06 28.6 2.5 0.00014 21.6 2.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGB10495.1 - 1.5e-06 28.6 0.2 0.0041 17.6 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EGB10495.1 - 2.6e-06 26.8 6.0 0.0028 16.8 1.4 3.0 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 EGB10495.1 - 2.7e-06 26.8 0.3 0.0035 16.6 0.2 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EGB10495.1 - 6.5e-06 25.5 3.8 0.003 16.7 0.2 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGB10495.1 - 7.6e-06 25.5 1.8 0.00025 20.6 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGB10495.1 - 4.1e-05 22.5 2.1 0.035 12.8 1.1 3.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 EGB10495.1 - 0.00034 20.0 1.3 0.11 11.7 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 EGB10495.1 - 0.0069 15.6 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGB10495.1 - 0.0072 16.5 0.6 0.035 14.3 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGB10495.1 - 0.0083 15.2 2.8 0.98 8.4 1.1 3.0 2 1 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EGB10495.1 - 0.058 12.2 2.0 0.5 9.1 0.8 2.2 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EGB10495.1 - 0.074 12.3 1.9 0.54 9.5 0.5 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DnaJ PF00226.31 EGB10496.1 - 2.2e-29 101.3 3.0 3e-29 100.9 3.0 1.2 1 0 0 1 1 1 1 DnaJ domain LRR_6 PF13516.6 EGB10497.1 - 4.1e-10 38.9 0.9 3.6e-05 23.5 0.0 3.2 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 EGB10497.1 - 0.00083 19.6 0.1 8.9 7.3 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.6 EGB10497.1 - 0.007 16.1 0.5 2.3 8.0 0.1 2.5 2 1 0 2 2 2 2 Leucine rich repeat GDP_Man_Dehyd PF16363.5 EGB10498.1 - 1.8e-68 231.4 0.0 2.1e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGB10498.1 - 3.1e-60 203.6 0.1 3.7e-60 203.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGB10498.1 - 1.1e-23 83.9 0.0 7.6e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGB10498.1 - 1.5e-22 80.0 0.0 1.9e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGB10498.1 - 2.7e-18 66.1 1.5 2.9e-17 62.7 0.8 2.4 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EGB10498.1 - 9.4e-16 57.7 0.0 1.1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGB10498.1 - 4.6e-05 23.4 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ABC1 PF03109.16 EGB10499.1 - 1e-25 90.2 0.0 1.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGB10499.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 EGB10499.1 - 0.24 11.3 9.8 0.19 11.6 6.9 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Lipase_GDSL_2 PF13472.6 EGB10500.1 - 2e-17 64.2 0.0 4e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_43 PF04616.14 EGB10500.1 - 8.3e-12 45.0 0.4 4.8e-11 42.5 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Lipase_GDSL PF00657.22 EGB10500.1 - 2.3e-06 27.7 0.0 3.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DEAD PF00270.29 EGB10501.1 - 4.4e-37 127.5 0.0 5.1e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB10501.1 - 0.00061 19.8 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGB10501.1 - 0.00075 19.8 0.0 0.052 13.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain Helicase_C PF00271.31 EGB10502.1 - 2e-25 89.3 0.0 2.4e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FIST_C PF10442.9 EGB10503.1 - 1.7e-19 70.1 0.4 4e-19 68.9 0.1 1.8 2 0 0 2 2 2 1 FIST C domain FIST PF08495.10 EGB10503.1 - 7.7e-16 58.6 0.7 7.7e-16 58.6 0.7 2.3 2 1 0 2 2 2 1 FIST N domain AAA PF00004.29 EGB10504.1 - 8.7e-23 81.2 0.0 1.5e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3523 PF12037.8 EGB10504.1 - 3.7e-18 65.9 0.2 5e-18 65.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA_16 PF13191.6 EGB10504.1 - 5.2e-08 33.5 1.5 3.8e-06 27.4 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB10504.1 - 5e-06 26.8 0.1 0.001 19.3 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGB10504.1 - 1.1e-05 25.5 0.6 9.2e-05 22.5 0.1 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGB10504.1 - 1.3e-05 25.0 0.0 6.3e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGB10504.1 - 0.00011 22.4 2.0 0.00077 19.6 0.2 2.8 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGB10504.1 - 0.00029 20.3 0.1 0.00084 18.8 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGB10504.1 - 0.0014 18.5 0.0 0.01 15.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGB10504.1 - 0.0051 17.4 0.0 0.012 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB10504.1 - 0.006 16.3 0.1 0.058 13.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EGB10504.1 - 0.012 15.3 0.0 0.49 10.0 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Rad17 PF03215.15 EGB10504.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 EGB10504.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 EGB10504.1 - 0.04 13.7 0.1 0.16 11.8 0.1 2.1 1 0 0 1 1 1 0 AAA+ lid domain TsaE PF02367.17 EGB10504.1 - 0.042 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EGB10504.1 - 0.046 14.0 0.1 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGB10504.1 - 0.05 13.3 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EGB10504.1 - 0.065 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EGB10504.1 - 0.072 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EGB10504.1 - 0.073 13.3 0.1 0.27 11.5 0.1 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB10504.1 - 0.08 12.8 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EGB10504.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 EGB10504.1 - 0.13 12.7 0.2 0.13 12.7 0.2 1.8 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 EGB10504.1 - 0.14 11.5 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein TIP49 PF06068.13 EGB10504.1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 EGB10504.1 - 0.2 11.8 0.0 0.4 10.8 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain adh_short_C2 PF13561.6 EGB10505.1 - 3.5e-64 216.5 6.6 4e-64 216.4 6.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB10505.1 - 1.2e-60 204.4 4.4 1.4e-60 204.1 4.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB10505.1 - 1.7e-17 63.9 1.6 2.6e-17 63.3 1.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB10505.1 - 0.027 13.9 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-CXXC PF02008.20 EGB10506.1 - 0.00041 20.3 0.7 0.00041 20.3 0.7 2.6 3 0 0 3 3 3 1 CXXC zinc finger domain LysM PF01476.20 EGB10506.1 - 0.01 15.9 0.0 3.5 7.7 0.0 3.0 3 0 0 3 3 3 0 LysM domain HSP90 PF00183.18 EGB10507.1 - 7.7e-229 760.9 23.2 1e-228 760.4 23.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGB10507.1 - 2.8e-14 53.6 0.0 6.1e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGB10507.1 - 8.2e-11 41.9 0.2 2.1e-10 40.6 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UIM PF02809.20 EGB10508.1 - 0.00031 20.4 50.9 0.0092 15.8 0.6 7.5 7 0 0 7 7 7 4 Ubiquitin interaction motif UN_NPL4 PF11543.8 EGB10508.1 - 0.028 14.9 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 EGB10508.1 - 0.22 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family IQ PF00612.27 EGB10508.1 - 0.64 10.0 10.6 0.17 11.8 1.6 3.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF2269 PF10027.9 EGB10509.1 - 0.036 14.1 0.3 0.44 10.6 0.2 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) ABC2_membrane PF01061.24 EGB10510.1 - 2.9e-14 53.0 0.9 5.6e-07 29.2 0.2 3.6 4 0 0 4 4 4 3 ABC-2 type transporter EMP70 PF02990.16 EGB10511.1 - 1.7e-202 673.7 1.0 1.7e-202 673.7 1.0 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 FMO-like PF00743.19 EGB10512.1 - 4e-59 200.4 0.0 5.2e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGB10512.1 - 7e-18 64.9 0.0 2.4e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB10512.1 - 3.1e-13 49.6 0.4 1.6e-11 44.0 0.0 2.3 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGB10512.1 - 7.1e-11 41.9 0.0 2.9e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RL11D PF11088.8 EGB10512.1 - 0.094 13.0 0.0 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 Sulfatase PF00884.23 EGB10513.1 - 6.5e-40 137.4 0.0 1e-39 136.8 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Cupin_8 PF13621.6 EGB10513.1 - 1.3e-13 51.2 0.0 3.6e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain DUF468 PF04318.12 EGB10513.1 - 0.061 14.0 0.0 10 6.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF468) Sulfatase_C PF14707.6 EGB10513.1 - 0.062 14.0 0.1 0.11 13.3 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase ARD PF03079.14 EGB10513.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Laminin_G_3 PF13385.6 EGB10514.1 - 1.9e-05 24.8 1.1 6.9e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily BNR_2 PF13088.6 EGB10514.1 - 0.068 12.5 0.0 0.2 10.9 0.0 1.8 1 0 0 1 1 1 0 BNR repeat-like domain BNR PF02012.20 EGB10514.1 - 0.085 12.9 14.5 0.22 11.6 0.8 4.9 4 0 0 4 4 4 0 BNR/Asp-box repeat Myosin_head PF00063.21 EGB10516.1 - 1.4e-136 456.5 0.0 9.6e-127 424.0 0.0 2.6 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 EGB10516.1 - 0.0058 17.0 0.1 0.0058 17.0 0.1 4.5 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EGB10516.1 - 0.0062 16.8 2.4 0.061 13.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EGB10516.1 - 0.05 13.9 1.3 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IQ PF00612.27 EGB10516.1 - 0.053 13.3 9.6 3.7 7.6 0.2 4.3 4 0 0 4 4 4 0 IQ calmodulin-binding motif YabA PF06156.13 EGB10516.1 - 0.1 13.2 1.2 15 6.3 0.3 3.3 2 1 0 3 3 3 0 Initiation control protein YabA SAP PF02037.27 EGB10517.1 - 1.2e-13 50.5 0.3 2.4e-13 49.5 0.3 1.6 1 0 0 1 1 1 1 SAP domain NusG PF02357.19 EGB10517.1 - 5.6e-11 42.8 0.2 1.2e-10 41.7 0.2 1.6 1 1 0 1 1 1 1 Transcription termination factor nusG FANC_SAP PF18081.1 EGB10517.1 - 0.1 12.8 0.2 0.1 12.8 0.2 4.0 5 0 0 5 5 5 0 Fanconi anemia-associated nuclease SAP domain Telomere_Sde2_2 PF13297.6 EGB10517.1 - 0.13 12.0 2.5 0.09 12.4 0.4 1.7 2 0 0 2 2 2 0 Telomere stability C-terminal KOW PF00467.29 EGB10517.1 - 0.15 12.1 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 KOW motif ILEI PF15711.5 EGB10518.1 - 6.2e-08 33.0 0.0 1.7e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Interleukin-like EMT inducer NFACT-C PF11923.8 EGB10519.1 - 3e-16 59.3 0.1 3.9e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 NFACT protein C-terminal domain DNA_photolyase PF00875.18 EGB10519.1 - 0.062 13.3 0.1 0.071 13.1 0.1 1.1 1 0 0 1 1 1 0 DNA photolyase CS PF04969.16 EGB10520.1 - 2.7e-09 37.9 0.0 3.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 CS domain Yop-YscD_cpl PF16697.5 EGB10521.1 - 0.00033 20.9 0.0 0.00063 20.0 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 EGB10521.1 - 0.00045 20.5 0.0 0.00074 19.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain LRR_8 PF13855.6 EGB10522.1 - 4.6e-12 45.5 8.0 5.9e-07 29.1 2.4 4.5 4 0 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGB10522.1 - 5.7e-10 39.3 2.1 0.16 12.4 0.2 4.7 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) YHYH PF14240.6 EGB10522.1 - 0.025 14.5 0.1 0.077 12.9 0.1 1.8 1 1 0 1 1 1 0 YHYH protein LRR_9 PF14580.6 EGB10522.1 - 0.049 13.1 0.7 8.1 5.9 0.2 2.7 2 1 0 2 2 2 0 Leucine-rich repeat GHL15 PF14885.6 EGB10523.1 - 8.2e-24 85.0 0.1 3.8e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase family 15 Tyr-DNA_phospho PF06087.12 EGB10523.1 - 3.6e-09 36.0 0.0 6.5e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase zf-MYND PF01753.18 EGB10523.1 - 8.3e-08 32.2 14.5 8.3e-08 32.2 14.5 2.3 2 0 0 2 2 2 1 MYND finger BRCT PF00533.26 EGB10523.1 - 0.0069 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGB10523.1 - 0.083 12.8 0.2 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 twin BRCT domain zf-HIT PF04438.16 EGB10523.1 - 2 8.4 6.5 4.7 7.2 6.5 1.7 1 0 0 1 1 1 0 HIT zinc finger Put_Phosphatase PF06888.12 EGB10524.1 - 1.9e-56 191.1 0.0 2.2e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 EGB10524.1 - 5.5e-05 23.6 0.7 0.00021 21.8 0.7 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Chloroa_b-bind PF00504.21 EGB10525.1 - 9.1e-33 114.1 0.0 1.1e-32 113.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2970 PF11174.8 EGB10525.1 - 0.11 12.4 1.5 7.2 6.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) Ion_trans PF00520.31 EGB10526.1 - 1.7e-24 86.4 11.7 2.1e-24 86.1 11.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB10526.1 - 3.1e-10 39.8 6.3 3.1e-10 39.8 6.3 1.8 2 0 0 2 2 1 1 Ion channel EF-hand_7 PF13499.6 EGB10526.1 - 5.5e-08 33.1 0.8 1.4e-07 31.8 0.8 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB10526.1 - 6.6e-08 32.3 2.7 0.00069 19.4 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB10526.1 - 1.1e-07 31.2 1.4 0.0011 18.7 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGB10526.1 - 1.8e-07 30.2 5.8 2.9e-05 23.3 0.4 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EGB10526.1 - 2e-07 30.2 1.1 1.5e-05 24.2 0.2 2.7 2 0 0 2 2 2 1 EF hand Lig_chan PF00060.26 EGB10526.1 - 9e-05 22.3 7.3 0.0031 17.4 1.4 2.2 2 0 0 2 2 2 2 Ligand-gated ion channel EF-hand_4 PF12763.7 EGB10526.1 - 0.015 15.2 1.2 3.2 7.7 0.0 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3671 PF12420.8 EGB10526.1 - 0.064 13.3 3.5 1.9 8.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function Peptidase_S68 PF10461.9 EGB10526.1 - 0.091 13.0 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 Peptidase S68 DUF5580 PF17743.1 EGB10526.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5580) TctB PF07331.11 EGB10526.1 - 0.24 11.7 2.9 0.87 9.9 1.1 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF21 PF01595.20 EGB10526.1 - 0.25 11.1 2.5 0.19 11.5 0.2 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Saf_2TM PF18303.1 EGB10526.1 - 1 8.9 6.7 9.8 5.8 4.2 3.1 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain Pox_I5 PF04713.12 EGB10526.1 - 1.2 9.2 5.0 1.5 8.9 1.0 2.9 3 0 0 3 3 3 0 Poxvirus protein I5 T3SSipB PF16535.5 EGB10527.1 - 0.91 10.0 5.5 2.8 8.4 0.6 4.4 3 0 0 3 3 3 0 Type III cell invasion protein SipB Cytochrome_CBB3 PF13442.6 EGB10528.1 - 4.5e-17 62.1 0.0 6.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EGB10528.1 - 8.8e-09 36.4 0.4 3.2e-08 34.6 0.4 1.8 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 EGB10528.1 - 2.1e-06 27.5 0.2 0.0012 18.6 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c-550 domain zf-RanBP PF00641.18 EGB10529.1 - 1.4e-05 24.3 3.0 2.5e-05 23.5 3.0 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others BRO1 PF03097.18 EGB10529.1 - 0.00058 18.8 0.0 0.0013 17.6 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain CH PF00307.31 EGB10530.1 - 2.1e-28 98.6 0.0 7.8e-15 55.0 0.0 2.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGB10530.1 - 0.0014 18.4 0.1 0.62 9.9 0.0 2.5 2 1 0 2 2 2 2 CAMSAP CH domain Nitroreductase PF00881.24 EGB10531.1 - 3.8e-16 59.6 0.4 1e-06 29.0 0.2 2.4 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 EGB10531.1 - 2.5e-05 24.0 0.0 0.0015 18.1 0.0 2.1 1 1 0 1 1 1 1 Putative TM nitroreductase WD40 PF00400.32 EGB10532.1 - 6.4e-16 58.5 6.1 0.0053 17.6 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.6 EGB10532.1 - 8.2e-10 38.7 4.1 8.5e-06 25.5 0.1 3.4 3 1 0 3 3 3 3 PQQ-like domain ANAPC4_WD40 PF12894.7 EGB10532.1 - 8e-08 32.5 0.0 0.24 11.7 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGB10532.1 - 0.0002 20.8 0.0 2 7.7 0.1 3.0 3 0 0 3 3 3 2 WD40-like domain PQQ_3 PF13570.6 EGB10532.1 - 0.019 15.4 19.1 0.13 12.7 2.7 5.8 5 1 1 6 6 6 0 PQQ-like domain Nup160 PF11715.8 EGB10532.1 - 0.25 9.9 0.1 14 4.2 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ PF01011.21 EGB10532.1 - 0.47 10.5 6.4 0.71 9.9 0.7 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat Methyltransf_3 PF01596.17 EGB10533.1 - 4.5e-13 48.9 0.0 5.7e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGB10533.1 - 1.2e-09 39.1 0.2 1.5e-09 38.9 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB10533.1 - 0.0093 15.7 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 EGB10534.1 - 1.9e-54 184.8 0.0 2.2e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10534.1 - 1.3e-36 126.3 0.0 1.5e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB10534.1 - 0.0049 15.7 0.0 0.0064 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB10534.1 - 0.0091 15.9 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB10534.1 - 0.042 13.2 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGB10534.1 - 0.1 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TylF PF05711.11 EGB10535.1 - 1.7e-52 178.2 0.0 2e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EGB10535.1 - 4.7e-06 27.6 0.0 8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGB10535.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DSPc PF00782.20 EGB10536.1 - 9.3e-12 44.9 0.0 1.1e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGB10536.1 - 0.0027 17.9 0.0 0.0032 17.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGB10536.1 - 0.0076 15.8 0.0 0.0078 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase cNMP_binding PF00027.29 EGB10537.1 - 1.7e-35 121.0 0.0 1.7e-19 69.7 0.0 2.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Pox_F16 PF04708.12 EGB10537.1 - 0.054 12.9 0.2 0.081 12.4 0.2 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein AAA_18 PF13238.6 EGB10538.1 - 2.3e-25 89.6 0.0 3.5e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB10538.1 - 3.8e-07 30.6 0.7 5.9e-07 30.0 0.7 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EGB10538.1 - 5.4e-06 26.9 0.1 1.7e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGB10538.1 - 9.5e-06 25.9 0.3 0.00032 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB10538.1 - 0.00025 21.2 0.1 0.0014 18.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGB10538.1 - 0.0006 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin2 PF13189.6 EGB10538.1 - 0.0017 18.5 0.1 0.0024 18.1 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_22 PF13401.6 EGB10538.1 - 0.002 18.4 0.1 0.0044 17.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGB10538.1 - 0.0034 17.8 0.6 0.019 15.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EGB10538.1 - 0.005 16.1 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGB10538.1 - 0.0058 16.4 0.2 0.014 15.2 0.1 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EGB10538.1 - 0.008 16.2 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SKI PF01202.22 EGB10538.1 - 0.0089 16.2 0.0 0.37 10.9 0.1 2.2 2 0 0 2 2 2 1 Shikimate kinase NTPase_1 PF03266.15 EGB10538.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 EGB10538.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EGB10538.1 - 0.018 14.3 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EGB10538.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGB10538.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGB10538.1 - 0.028 14.1 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain dNK PF01712.19 EGB10538.1 - 0.031 14.1 0.1 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase 2-Hacid_dh PF00389.30 EGB10538.1 - 0.034 13.8 0.0 0.048 13.3 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MeaB PF03308.16 EGB10538.1 - 0.046 12.7 0.9 0.062 12.3 0.2 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Hydin_ADK PF17213.3 EGB10538.1 - 0.058 13.7 0.2 0.096 13.0 0.2 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain T2SSE PF00437.20 EGB10538.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGB10538.1 - 0.065 12.6 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGB10538.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGB10538.1 - 0.073 13.5 0.0 0.17 12.3 0.0 1.6 2 0 0 2 2 1 0 RNA helicase APS_kinase PF01583.20 EGB10538.1 - 0.078 12.9 0.1 0.48 10.3 0.1 2.0 1 1 1 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.15 EGB10538.1 - 0.088 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 EGB10538.1 - 0.099 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 EGB10538.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 EGB10538.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 EGB10538.1 - 0.18 11.4 0.1 1.1 8.9 0.1 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_2 PF07724.14 EGB10538.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ArsA_ATPase PF02374.15 EGB10538.1 - 0.22 10.6 0.2 0.45 9.7 0.2 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_7 PF12775.7 EGB10538.1 - 0.25 10.8 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Phytochelatin PF05023.14 EGB10539.1 - 3.9e-77 258.3 0.0 4.3e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 EGB10539.1 - 0.0015 19.1 0.2 1.2 9.7 0.0 2.9 2 1 1 3 3 3 2 Peptidase_C39 like family DUF3335 PF11814.8 EGB10539.1 - 0.074 12.5 0.3 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Peptidase_C39 like family TPR_2 PF07719.17 EGB10540.1 - 3.2e-10 39.3 11.4 0.00032 20.6 0.5 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB10540.1 - 7.8e-10 38.2 10.4 0.0014 18.4 1.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB10540.1 - 5.6e-06 25.9 1.6 0.0031 17.2 0.2 3.1 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.6 EGB10540.1 - 5.9e-06 26.3 10.9 5.8e-05 23.2 6.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10540.1 - 2.4e-05 24.2 3.7 0.007 16.5 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB10540.1 - 2.7e-05 24.6 11.9 0.027 15.3 2.9 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB10540.1 - 0.00031 20.7 0.5 0.00088 19.3 0.1 1.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 EGB10540.1 - 0.0007 20.2 15.7 0.0031 18.1 3.2 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB10540.1 - 0.0013 18.6 5.0 0.0023 17.8 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10540.1 - 0.0036 17.6 11.0 0.056 13.7 2.3 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat CinA_KH PF18146.1 EGB10540.1 - 0.016 15.4 0.5 0.07 13.3 0.1 2.1 2 1 0 2 2 2 0 Damage-inducible protein CinA KH domain TPR_6 PF13174.6 EGB10540.1 - 0.056 14.1 5.8 2.6 8.9 0.4 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGB10540.1 - 0.87 9.3 8.5 0.17 11.6 2.4 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain Lipase_GDSL_2 PF13472.6 EGB10541.1 - 2.1e-24 86.9 0.9 2.1e-24 86.9 0.9 2.2 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_11 PF08241.12 EGB10541.1 - 4.8e-17 62.4 0.0 1.1e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB10541.1 - 1.4e-15 57.7 0.0 3.9e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10541.1 - 1.9e-11 44.6 0.0 6.4e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB10541.1 - 4.2e-09 36.1 0.0 9.6e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGB10541.1 - 3.4e-08 33.4 0.0 5.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB10541.1 - 1.7e-07 31.3 0.0 3.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Lipase_GDSL PF00657.22 EGB10541.1 - 2.1e-06 27.9 0.0 4.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Methyltransf_2 PF00891.18 EGB10541.1 - 3.2e-05 23.3 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGB10541.1 - 0.0048 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EGB10541.1 - 0.014 15.2 0.0 0.098 12.5 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Glucan_synthase PF02364.15 EGB10542.1 - 8.3e-129 431.1 0.0 9.3e-129 430.9 0.0 1.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase component RRM_1 PF00076.22 EGB10543.1 - 5.4e-20 71.0 0.0 5.9e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGB10543.1 - 0.0054 16.6 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EGB10543.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EGB10543.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.16 EGB10544.1 - 2e-08 33.5 37.4 2e-08 33.5 37.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Proteasome PF00227.26 EGB10545.1 - 4e-28 98.2 0.0 4.9e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGB10545.1 - 7.4e-10 38.3 0.0 1.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps36-NZF-N PF16988.5 EGB10545.1 - 0.035 13.5 0.0 0.081 12.3 0.0 1.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain His_biosynth PF00977.21 EGB10546.1 - 1.3e-29 103.3 0.4 1.7e-29 102.9 0.4 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 EGB10546.1 - 0.22 10.7 0.2 0.33 10.1 0.2 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase GcpE PF04551.14 EGB10547.1 - 1e-141 472.1 0.0 1.5e-141 471.6 0.0 1.2 1 0 0 1 1 1 1 GcpE protein adh_short PF00106.25 EGB10547.1 - 8.8e-41 139.5 0.4 1.6e-40 138.7 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB10547.1 - 4.1e-38 131.3 2.5 8.5e-38 130.2 2.5 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TPR_1 PF00515.28 EGB10547.1 - 5.7e-07 29.1 2.4 0.0044 16.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10547.1 - 9.9e-06 25.3 5.0 0.02 15.0 0.3 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat KR PF08659.10 EGB10547.1 - 1.1e-05 25.4 1.0 3.2e-05 23.9 1.0 1.8 1 0 0 1 1 1 1 KR domain TPR_12 PF13424.6 EGB10547.1 - 0.0035 17.6 4.7 0.041 14.2 3.8 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 EGB10547.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 AT_hook PF02178.19 EGB10547.1 - 0.37 10.8 82.9 0.24 11.4 2.9 7.8 7 0 0 7 7 7 0 AT hook motif Complex1_LYR PF05347.15 EGB10548.1 - 2.7e-08 33.8 0.4 4.4e-08 33.1 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EGB10548.1 - 0.00066 20.2 0.1 0.00094 19.7 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 EGB10548.1 - 0.0021 18.8 0.8 0.0031 18.2 0.1 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Peptidase_S49 PF01343.18 EGB10550.1 - 1.6e-25 89.8 0.0 1.9e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 EGB10550.1 - 6.2e-06 26.4 0.5 1e-05 25.6 0.5 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal CLP_protease PF00574.23 EGB10550.1 - 0.032 14.1 0.1 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Clp protease Sigma70_r2 PF04542.14 EGB10551.1 - 4e-20 71.4 1.8 5.7e-20 70.9 0.2 2.1 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EGB10551.1 - 3.5e-14 52.1 1.1 1.2e-13 50.4 0.4 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 EGB10551.1 - 9.9e-08 32.0 1.8 7.3e-06 26.0 0.1 3.1 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 EGB10551.1 - 0.006 16.6 0.2 0.015 15.3 0.2 1.6 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 KORA PF16509.5 EGB10551.1 - 0.068 13.4 1.0 0.21 11.9 0.2 2.2 2 1 2 4 4 4 0 TrfB plasmid transcriptional repressor GDI PF00996.18 EGB10552.1 - 1.7e-177 590.3 0.0 2.4e-177 589.9 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Ketoacyl-synt_C PF02801.22 EGB10552.1 - 3.6e-33 114.1 2.2 6.6e-33 113.2 2.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGB10552.1 - 1.3e-22 80.6 8.9 1.3e-22 80.6 8.9 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EGB10552.1 - 0.0013 18.1 0.5 0.0013 18.1 0.5 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EGB10552.1 - 0.015 15.8 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Peptidase_M20 PF01546.28 EGB10553.1 - 1.8e-24 86.6 0.8 2.4e-24 86.2 0.8 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGB10553.1 - 6.8e-06 26.0 0.1 1.9e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain PNP_UDP_1 PF01048.20 EGB10554.1 - 6e-24 84.6 0.8 7.2e-24 84.3 0.8 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.25 EGB10555.1 - 5e-54 183.4 0.0 5.7e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10555.1 - 1.1e-30 106.8 0.0 1.3e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB10555.1 - 4.5e-05 23.5 0.1 7.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB10555.1 - 0.00032 20.1 0.4 0.0016 17.8 0.2 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB10555.1 - 0.0038 16.1 0.0 0.0052 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGB10555.1 - 0.0061 15.6 0.1 0.0086 15.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGB10555.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M3 PF01432.20 EGB10556.1 - 1.7e-126 423.1 0.0 2.3e-126 422.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EGB10556.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Effector protein Shugoshin_C PF07557.11 EGB10556.1 - 0.2 11.5 0.3 0.37 10.6 0.3 1.5 1 0 0 1 1 1 0 Shugoshin C terminus TRAM_LAG1_CLN8 PF03798.16 EGB10557.1 - 1.1e-31 110.1 6.8 1.3e-31 109.9 6.8 1.0 1 0 0 1 1 1 1 TLC domain DSPc PF00782.20 EGB10559.1 - 0.03 14.1 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Rpn9_C PF18261.1 EGB10559.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Rpn9 C-terminal helix HSP70 PF00012.20 EGB10560.1 - 5.5e-28 97.5 1.4 1.2e-27 96.4 1.4 1.5 1 1 0 1 1 1 1 Hsp70 protein Gal-3-0_sulfotr PF06990.11 EGB10561.1 - 1e-13 51.0 1.3 7e-13 48.2 0.0 2.6 3 1 0 3 3 3 1 Galactose-3-O-sulfotransferase Sulfatase PF00884.23 EGB10562.1 - 5e-42 144.4 0.0 6e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EGB10562.1 - 0.015 13.9 0.1 0.022 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Ephrin_rec_like PF07699.13 EGB10563.1 - 7.3e-35 118.5 94.4 2.7e-07 30.2 5.5 9.4 2 1 8 10 10 10 8 Putative ephrin-receptor like REJ PF02010.15 EGB10563.1 - 8.8e-15 54.4 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 REJ domain NCD3G PF07562.14 EGB10563.1 - 8e-09 35.3 63.6 0.022 14.7 1.2 9.2 3 2 5 11 11 11 9 Nine Cysteines Domain of family 3 GPCR SKN1 PF03935.15 EGB10564.1 - 3.4e-56 190.7 4.3 3.5e-48 164.3 1.1 2.9 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Lipase_GDSL_2 PF13472.6 EGB10564.1 - 2.8e-10 40.9 0.1 2.8e-10 40.9 0.1 2.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_16 PF00722.21 EGB10564.1 - 1.1e-08 34.7 0.2 8.1e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Lipase_GDSL PF00657.22 EGB10564.1 - 1.4e-05 25.2 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peptidase_C2 PF00648.21 EGB10565.1 - 1.2e-21 77.0 0.0 1.4e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease THF_DHG_CYH PF00763.23 EGB10566.1 - 5e-22 78.4 0.0 7.9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EGB10566.1 - 2.7e-14 52.8 0.9 1.7e-13 50.2 0.9 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 EGB10566.1 - 0.0049 17.0 0.0 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain UDPG_MGDP_dh_N PF03721.14 EGB10566.1 - 0.023 14.3 0.1 1.8 8.1 0.0 2.2 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EGB10566.1 - 0.063 13.9 0.1 0.11 13.1 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_28 PF03033.20 EGB10567.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGB10567.1 - 0.011 14.6 0.6 0.014 14.2 0.6 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Myb_DNA-binding PF00249.31 EGB10568.1 - 1.7e-27 95.4 3.4 1.1e-08 35.1 0.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB10568.1 - 1.4e-19 70.1 0.1 4.5e-06 26.8 0.0 3.2 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB10568.1 - 0.00031 20.6 0.0 0.0047 16.8 0.0 2.4 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EGB10568.1 - 0.051 13.8 0.1 23 5.3 0.0 3.1 2 1 0 2 2 2 0 Rap1 Myb domain UDPGP PF01704.18 EGB10569.1 - 1.9e-11 43.3 0.0 3.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ELMO_CED12 PF04727.13 EGB10570.1 - 6e-30 104.7 0.0 1.1e-29 103.8 0.0 1.4 2 0 0 2 2 2 1 ELMO/CED-12 family mTERF PF02536.14 EGB10571.1 - 9.1e-36 123.4 0.0 5e-19 68.4 0.0 4.0 2 1 1 3 3 3 3 mTERF Glyco_tranf_2_4 PF13704.6 EGB10572.1 - 3.5e-07 30.6 0.3 1.2e-05 25.7 0.3 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 EF-hand_6 PF13405.6 EGB10573.1 - 7e-07 28.7 5.4 0.00063 19.5 0.3 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGB10573.1 - 6e-06 25.4 6.0 0.0029 17.0 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB10573.1 - 3e-05 24.4 5.9 0.005 17.3 0.2 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB10573.1 - 0.0015 17.9 7.4 0.0024 17.3 0.7 2.9 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 EGB10573.1 - 0.0025 18.1 1.5 0.088 13.1 0.0 2.5 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EGB10573.1 - 0.0047 16.7 1.4 3.5 7.5 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EGB10573.1 - 0.066 13.2 3.9 1.9 8.5 0.3 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Asp PF00026.23 EGB10574.1 - 3e-19 69.6 0.0 1.6e-08 34.4 0.0 2.1 1 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGB10574.1 - 8.7e-19 68.4 0.2 8.7e-19 68.4 0.2 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGB10574.1 - 0.14 12.0 0.0 0.48 10.2 0.0 2.0 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal PRCC PF10253.9 EGB10574.1 - 9.5 6.9 6.3 16 6.2 5.9 1.6 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PAS_8 PF13188.7 EGB10575.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain CDC27 PF09507.10 EGB10575.1 - 3.1 7.1 12.5 0.35 10.2 7.6 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DKCLD PF08068.12 EGB10576.1 - 1.9e-34 117.5 0.1 1.2e-32 111.7 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EGB10576.1 - 8.6e-25 87.8 0.4 7.7e-21 75.0 0.4 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EGB10576.1 - 1e-20 73.5 1.6 1.8e-20 72.6 1.6 1.4 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 EGB10576.1 - 1.3e-20 73.3 1.6 2.2e-20 72.6 1.6 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 EGB10576.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain Far-17a_AIG1 PF04750.14 EGB10577.1 - 2.2e-06 27.1 0.5 3.6e-06 26.5 0.5 1.4 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein DnaJ PF00226.31 EGB10578.1 - 2.1e-18 66.2 0.0 2.4e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain Sel1 PF08238.12 EGB10579.1 - 2.4e-19 69.3 14.5 1e-08 35.5 0.5 4.7 4 1 0 4 4 4 4 Sel1 repeat TPR_11 PF13414.6 EGB10579.1 - 0.0051 16.5 0.5 1.9 8.3 0.2 3.2 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.28 EGB10579.1 - 0.023 14.5 3.3 21 5.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10579.1 - 0.068 13.3 10.1 3.5 8.0 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGB10579.1 - 0.13 12.3 0.9 9.2 6.4 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB10579.1 - 1.2 9.9 11.9 0.92 10.2 1.3 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat Sulfotransfer_4 PF17784.1 EGB10580.1 - 6.4e-32 111.1 0.1 2.5e-31 109.2 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB10580.1 - 0.015 15.7 0.7 2 8.7 0.1 2.6 2 1 1 3 3 3 0 Sulfotransferase family Ribul_P_3_epim PF00834.19 EGB10581.1 - 3.5e-37 127.7 0.0 5.4e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family FGGY_N PF00370.21 EGB10581.1 - 2.2e-31 109.3 0.0 5.2e-28 98.3 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGB10581.1 - 9.9e-30 103.7 0.6 3.3e-29 102.0 0.2 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Kelch_6 PF13964.6 EGB10582.1 - 0.0003 21.0 3.5 1.1 9.7 0.1 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EGB10582.1 - 0.00046 20.4 20.8 0.052 13.9 0.8 6.6 6 2 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB10582.1 - 0.00066 19.6 5.1 1.4 9.0 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EGB10582.1 - 0.0008 18.9 4.1 0.11 12.1 0.6 5.0 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 EGB10582.1 - 0.002 18.0 3.8 0.005 16.8 0.1 3.3 2 1 0 2 2 2 1 Kelch motif Mem_trans PF03547.18 EGB10583.1 - 1.3e-07 30.4 8.9 2.5e-05 22.9 1.2 2.3 1 1 1 2 2 2 2 Membrane transport protein Ion_trans PF00520.31 EGB10583.1 - 0.0013 18.0 0.7 0.0028 16.9 0.7 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB10583.1 - 0.0014 18.5 2.3 0.0076 16.2 2.3 2.4 1 0 0 1 1 1 1 Ion channel Castor_Poll_mid PF06241.12 EGB10583.1 - 0.16 12.0 0.0 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel DUF3149 PF11346.8 EGB10583.1 - 0.93 9.2 3.3 0.7 9.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Histone PF00125.24 EGB10584.1 - 5.3e-19 68.9 0.4 6.3e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB10584.1 - 1.9e-05 24.8 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB10584.1 - 0.0038 17.7 0.0 0.0059 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB10584.1 - 0.053 13.6 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein CENP-T_C PF15511.6 EGB10585.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB10585.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB10585.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB10585.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB10585.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB10585.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB10585.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGB10585.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EGB10586.1 - 5.4e-19 68.8 0.4 6.5e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB10586.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB10586.1 - 0.0039 17.7 0.0 0.0061 17.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB10586.1 - 0.054 13.5 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein TauD PF02668.16 EGB10587.1 - 5.5e-28 98.5 0.0 8.8e-28 97.8 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hjc PF01870.18 EGB10587.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) AAA_26 PF13500.6 EGB10588.1 - 3.3e-19 69.5 0.0 3.7e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain Rpn3_C PF08375.11 EGB10589.1 - 4.2e-26 91.2 1.9 8.6e-26 90.2 1.1 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EGB10589.1 - 1.9e-20 73.3 0.1 1.8e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain ANAPC3 PF12895.7 EGB10589.1 - 0.036 14.3 0.9 0.27 11.5 0.2 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGB10589.1 - 0.052 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Malate_DH PF12434.8 EGB10589.1 - 0.29 11.2 3.0 0.25 11.4 0.3 2.4 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Phage_CP76 PF06892.11 EGB10590.1 - 0.019 14.5 0.2 0.033 13.7 0.2 1.3 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) ABC2_membrane PF01061.24 EGB10591.1 - 1e-45 155.7 13.9 3.7e-27 95.1 1.8 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGB10591.1 - 1.5e-27 96.8 0.0 8.6e-13 49.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EGB10591.1 - 2.4e-07 30.8 0.9 0.023 14.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB10591.1 - 0.00039 20.8 1.9 0.48 10.8 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGB10591.1 - 0.00052 19.7 2.6 0.31 10.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB10591.1 - 0.002 18.2 2.5 0.97 9.5 0.3 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 EGB10591.1 - 0.0033 16.6 11.7 0.04 13.0 1.6 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein NACHT PF05729.12 EGB10591.1 - 0.0067 16.4 3.3 0.54 10.2 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EGB10591.1 - 0.0079 16.5 2.1 1.5 9.1 0.3 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 EGB10591.1 - 0.021 14.7 1.0 2.3 8.1 0.1 2.6 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EGB10591.1 - 0.032 14.6 1.5 8.7 6.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGB10591.1 - 0.034 13.6 0.0 0.6 9.5 0.0 2.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB10591.1 - 0.04 13.6 3.7 3 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB10591.1 - 0.05 13.0 1.4 0.3 10.4 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EGB10591.1 - 0.058 13.6 3.7 3.4 7.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGB10591.1 - 0.075 12.6 5.2 2.4 7.7 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGB10591.1 - 0.079 12.7 1.1 8.5 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGB10591.1 - 0.091 13.2 1.3 9 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGB10591.1 - 0.2 10.7 0.3 16 4.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EGB10591.1 - 0.24 11.8 1.5 15 6.0 0.1 2.4 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 EGB10591.1 - 0.6 10.0 4.2 4 7.3 0.1 3.0 3 0 0 3 3 3 0 NTPase MeaB PF03308.16 EGB10591.1 - 0.67 8.9 3.7 0.49 9.3 1.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EGB10591.1 - 1.7 8.2 3.3 10 5.7 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 EGB10591.1 - 3.5 7.7 4.5 19 5.3 0.1 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 EGB10591.1 - 4.7 7.2 5.9 16 5.5 0.4 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain DJ-1_PfpI PF01965.24 EGB10592.1 - 4.6e-16 59.1 0.0 1.6e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGB10592.1 - 4.7e-07 29.7 2.5 0.00014 21.6 2.4 2.9 1 1 0 1 1 1 1 ThiJ/PfpI family-like ketoacyl-synt PF00109.26 EGB10593.1 - 1.8e-33 116.2 10.6 2.4e-33 115.8 10.6 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB10593.1 - 5.1e-05 23.3 0.6 0.00044 20.2 0.6 2.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB10593.1 - 1.4 8.2 6.3 0.11 11.8 1.0 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 EGB10594.1 - 4.4e-33 114.9 10.2 5.8e-33 114.5 10.2 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB10594.1 - 5.5e-05 23.2 0.6 0.00044 20.2 0.6 2.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB10594.1 - 1.4 8.2 6.3 0.11 11.8 1.0 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 EGB10595.1 - 9.2e-30 104.1 10.7 1.4e-29 103.4 10.7 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB10595.1 - 5.4e-07 29.6 1.0 1e-06 28.7 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB10595.1 - 0.0014 18.1 0.7 0.0019 17.6 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 EGB10596.1 - 4.2e-29 101.9 12.0 6.3e-29 101.3 12.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB10596.1 - 4.5e-07 29.9 1.0 8.2e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB10596.1 - 0.0012 18.2 0.7 0.0017 17.8 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ECH_1 PF00378.20 EGB10597.1 - 1.4e-15 57.3 0.0 1.9e-15 56.9 0.0 1.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGB10597.1 - 4.8e-07 29.6 1.7 2.7e-06 27.1 1.7 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 EGB10598.1 - 4.7e-34 118.1 7.6 7.3e-34 117.5 7.6 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB10598.1 - 7.1e-07 29.3 0.1 1.5e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EGB10598.1 - 0.004 17.0 0.2 0.012 15.5 0.2 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EGB10598.1 - 0.044 13.1 0.2 0.076 12.4 0.2 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Peptidase_C1 PF00112.23 EGB10599.1 - 2.9e-59 200.8 0.1 3.2e-59 200.6 0.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Pilin_PilA PF14245.6 EGB10600.1 - 0.071 13.1 1.2 3.3 7.7 0.0 2.8 2 1 1 3 3 3 0 Type IV pilin PilA XS PF03468.14 EGB10600.1 - 0.13 12.5 1.0 3.4 8.0 0.0 2.8 2 1 0 3 3 3 0 XS domain YgaB PF14182.6 EGB10602.1 - 0.13 12.7 0.0 15 6.0 0.0 2.3 2 0 0 2 2 2 0 YgaB-like protein VGLL4 PF15245.6 EGB10602.1 - 0.2 11.7 1.9 0.29 11.2 1.8 1.3 1 1 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 NTP_transferase PF00483.23 EGB10603.1 - 1.9e-10 40.8 0.0 2.9e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase GHMP_kinases_N PF00288.26 EGB10603.1 - 5.9e-07 29.6 0.1 1.4e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Peptidase_S10 PF00450.22 EGB10605.1 - 1.2e-56 192.9 0.0 1.5e-56 192.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Kinesin PF00225.23 EGB10606.1 - 3.3e-94 315.6 0.0 4e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB10606.1 - 2.4e-19 69.8 0.0 6.7e-19 68.3 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding WW PF00397.26 EGB10606.1 - 2.8e-08 33.7 1.1 5.9e-08 32.7 1.1 1.6 1 0 0 1 1 1 1 WW domain DUF4194 PF13835.6 EGB10606.1 - 0.044 13.5 1.1 0.096 12.4 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Cep57_CLD_2 PF14197.6 EGB10606.1 - 0.45 10.6 5.6 0.14 12.3 0.7 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Acyl-CoA_dh_1 PF00441.24 EGB10607.1 - 2.2e-30 105.8 7.4 5.9e-30 104.5 7.4 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGB10607.1 - 4.1e-30 104.7 0.1 1.1e-29 103.3 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGB10607.1 - 1.2e-19 70.3 0.0 2.2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGB10607.1 - 4.5e-15 56.1 6.5 4.5e-15 56.1 6.5 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain EF-hand_7 PF13499.6 EGB10608.1 - 7.5e-10 39.1 4.7 1.9e-09 37.8 4.2 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB10608.1 - 8.9e-06 25.2 3.2 0.0034 17.2 1.0 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGB10608.1 - 0.00019 20.7 13.4 0.013 15.0 0.5 3.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EGB10608.1 - 0.0023 17.7 3.5 0.0065 16.3 1.4 2.5 2 1 1 3 3 3 1 EF-hand domain pair TerB PF05099.13 EGB10608.1 - 0.09 12.7 0.1 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TerB Asn_synthase PF00733.21 EGB10609.1 - 1.3e-08 35.0 1.1 0.00023 20.9 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase RBP_receptor PF14752.6 EGB10610.1 - 5.9e-14 51.6 0.1 2.1e-12 46.4 0.1 2.2 2 0 0 2 2 2 2 Retinol binding protein receptor EF-hand_7 PF13499.6 EGB10610.1 - 0.13 12.7 0.0 0.53 10.8 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair TMEM65 PF10507.9 EGB10611.1 - 8.7e-36 122.2 1.8 9.9e-36 122.0 1.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 Shadoo PF14999.6 EGB10611.1 - 0.0062 16.6 0.3 0.0088 16.1 0.3 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Romo1 PF10247.9 EGB10611.1 - 0.019 15.3 5.0 0.027 14.8 0.0 2.7 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Bacteriocin_IIc PF10439.9 EGB10611.1 - 0.37 10.9 6.7 3 8.0 0.3 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Thioredoxin PF00085.20 EGB10612.1 - 4.3e-19 68.4 0.0 6.8e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TPR_20 PF14561.6 EGB10612.1 - 9.3e-06 25.9 5.9 9.3e-06 25.9 5.9 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Thioredoxin_7 PF13899.6 EGB10612.1 - 0.00072 19.7 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB10612.1 - 0.01 16.3 0.2 0.33 11.4 0.2 2.4 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 EGB10612.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EGB10612.1 - 0.046 14.0 0.0 0.26 11.7 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EGB10612.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin ADK PF00406.22 EGB10613.1 - 1.1e-43 148.9 0.0 1.5e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGB10613.1 - 3e-25 89.2 0.2 9.7e-25 87.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EGB10613.1 - 4.2e-06 26.6 0.5 0.016 14.9 0.0 2.6 1 1 2 3 3 3 2 Thymidylate kinase AAA_18 PF13238.6 EGB10613.1 - 0.00054 20.5 0.1 0.0015 19.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB10613.1 - 0.0095 16.1 0.6 0.14 12.3 0.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGB10613.1 - 0.12 12.6 0.1 0.25 11.6 0.0 1.6 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EGB10614.1 - 2.1e-37 128.7 0.0 1.1e-23 84.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGB10614.1 - 5e-23 82.1 2.0 6.1e-13 49.0 0.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGB10614.1 - 1.4e-06 27.9 0.2 0.88 9.0 0.0 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB10614.1 - 4.7e-05 23.8 0.6 0.015 15.7 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EGB10614.1 - 0.00022 21.3 0.3 0.16 12.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 EGB10614.1 - 0.00024 20.8 0.1 0.97 9.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB10614.1 - 0.0026 17.7 0.1 0.075 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGB10614.1 - 0.005 16.9 0.3 2 8.5 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EGB10614.1 - 0.0082 16.0 0.3 5.5 6.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGB10614.1 - 0.018 15.3 0.0 0.94 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGB10614.1 - 0.02 15.3 0.0 1.6 9.2 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) VGCC_beta4Aa_N PF12052.8 EGB10614.1 - 0.033 14.3 1.4 0.64 10.2 0.1 2.9 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal AAA_23 PF13476.6 EGB10614.1 - 0.04 14.4 0.0 8.4 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGB10614.1 - 0.042 12.9 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Rad17 PF03215.15 EGB10614.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 EGB10614.1 - 0.13 12.0 0.0 18 4.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_PrkA PF08298.11 EGB10614.1 - 0.26 10.1 0.0 0.59 9.0 0.0 1.5 1 0 0 1 1 1 0 PrkA AAA domain AAA_33 PF13671.6 EGB10614.1 - 1.1 9.4 3.3 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain CTP_transf_3 PF02348.19 EGB10615.1 - 2.3e-23 83.3 0.0 3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 EGB10615.1 - 9.1e-06 26.1 1.4 1.1e-05 25.9 1.4 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Abhydrolase_6 PF12697.7 EGB10616.1 - 1.8e-19 71.2 9.3 2.2e-19 71.0 9.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB10616.1 - 3e-19 69.7 0.1 1.3e-18 67.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB10616.1 - 1.1e-11 44.5 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 EGB10616.1 - 0.0091 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ank_4 PF13637.6 EGB10617.1 - 6.2e-21 74.5 2.4 3.5e-08 33.8 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB10617.1 - 5.4e-18 65.4 0.9 7.8e-10 39.2 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGB10617.1 - 2.9e-15 55.9 5.9 0.00017 21.9 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGB10617.1 - 1.3e-13 49.8 0.3 0.0033 17.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGB10617.1 - 6.9e-12 45.4 1.9 6.6e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Se-cys_synth_N PF12390.8 EGB10617.1 - 0.99 9.7 5.2 4.9 7.5 0.6 2.6 2 1 0 2 2 2 0 Selenocysteine synthase N terminal Trypan_PARP PF05887.11 EGB10618.1 - 0.00044 20.2 21.9 0.00044 20.2 21.9 3.2 1 1 2 3 3 3 1 Procyclic acidic repetitive protein (PARP) Aminotran_3 PF00202.21 EGB10619.1 - 1.5e-106 356.5 0.0 1.9e-106 356.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EGB10619.1 - 0.055 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Nuc_sug_transp PF04142.15 EGB10620.1 - 5.5e-08 32.3 2.3 1.3e-07 31.1 2.3 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB10620.1 - 8.9e-05 22.7 4.8 8.9e-05 22.7 4.8 2.0 2 0 0 2 2 2 1 EamA-like transporter family EF-hand_1 PF00036.32 EGB10620.1 - 0.0019 17.6 1.6 1.1 9.0 0.2 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB10620.1 - 0.014 15.8 5.2 0.17 12.4 0.5 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EGB10620.1 - 0.068 13.1 0.9 19 5.5 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 EGB10620.1 - 0.52 10.2 5.5 0.61 10.0 0.4 2.9 3 0 0 3 3 3 0 EF-hand domain pair ABC_tran PF00005.27 EGB10622.1 - 4.8e-42 143.7 0.5 4.3e-19 69.4 0.0 4.6 4 1 0 4 4 3 3 ABC transporter AAA_21 PF13304.6 EGB10622.1 - 2.2e-15 57.3 0.1 0.0067 16.3 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB10622.1 - 3.1e-11 43.1 0.1 0.007 15.8 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB10622.1 - 5.3e-08 32.5 0.1 0.01 15.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB10622.1 - 6.1e-07 30.1 22.5 0.0041 17.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EGB10622.1 - 1.4e-06 28.4 0.2 0.0071 16.4 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB10622.1 - 4.3e-06 27.2 0.0 0.097 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGB10622.1 - 8.1e-06 25.8 4.0 0.0057 16.6 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 EGB10622.1 - 2.9e-05 24.3 0.0 0.035 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGB10622.1 - 3.2e-05 23.8 5.5 0.44 10.2 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EGB10622.1 - 0.00026 21.2 0.0 0.12 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB10622.1 - 0.00044 20.2 0.3 0.64 9.9 0.7 2.8 2 1 0 2 2 2 1 NACHT domain AAA PF00004.29 EGB10622.1 - 0.00056 20.3 0.6 0.68 10.4 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB10622.1 - 0.0011 19.3 0.0 2.8 8.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 EGB10622.1 - 0.0012 18.0 0.1 0.36 9.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 EGB10622.1 - 0.0033 17.2 0.0 1.9 8.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 EGB10622.1 - 0.0044 17.3 6.7 0.12 12.6 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 EGB10622.1 - 0.0048 17.4 0.0 3.3 8.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EGB10622.1 - 0.0073 16.5 0.0 1 9.6 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EGB10622.1 - 0.013 15.0 1.0 0.5 9.8 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EGB10622.1 - 0.017 14.9 0.0 7.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 EGB10622.1 - 0.017 15.4 0.1 7.5 6.9 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 EGB10622.1 - 0.018 14.6 5.7 1.9 8.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 EGB10622.1 - 0.021 14.0 0.1 6.3 5.9 0.0 3.0 2 1 0 2 2 2 0 G-protein alpha subunit MeaB PF03308.16 EGB10622.1 - 0.025 13.6 5.7 0.35 9.8 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 EGB10622.1 - 0.026 14.5 0.6 6.1 6.7 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_14 PF13173.6 EGB10622.1 - 0.031 14.3 0.0 5.9 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGB10622.1 - 0.067 13.2 0.1 7.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Adeno_IVa2 PF02456.15 EGB10622.1 - 0.079 11.7 0.1 10 4.8 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein MukB PF04310.12 EGB10622.1 - 0.11 12.2 0.1 15 5.3 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal Viral_helicase1 PF01443.18 EGB10622.1 - 0.15 11.8 0.0 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 EGB10622.1 - 0.2 11.7 0.0 0.2 11.7 0.0 3.6 3 1 1 4 4 4 0 Dynamin family IstB_IS21 PF01695.17 EGB10622.1 - 0.21 11.3 0.9 12 5.6 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EGB10622.1 - 0.37 10.7 7.8 6.9 6.5 0.0 3.4 3 1 0 3 3 2 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 EGB10622.1 - 0.52 9.8 1.8 11 5.5 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B GDP_Man_Dehyd PF16363.5 EGB10623.1 - 2.2e-61 208.1 0.0 6.7e-61 206.5 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGB10623.1 - 3.3e-54 183.9 0.0 4e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB10623.1 - 1.8e-20 73.1 0.0 2.4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGB10623.1 - 2e-16 60.0 0.0 2.5e-15 56.4 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGB10623.1 - 4.7e-13 48.9 0.0 6.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGB10623.1 - 1.6e-09 38.0 0.1 3.2e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EGB10623.1 - 2.8e-09 36.5 0.1 1.7e-08 34.0 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGB10623.1 - 1.4e-05 25.1 0.1 3.3e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EGB10623.1 - 8.8e-05 22.0 2.2 0.0011 18.5 2.2 2.5 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 EGB10623.1 - 0.017 15.3 0.2 0.067 13.4 0.2 1.9 1 1 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.12 EGB10623.1 - 0.022 15.4 0.1 0.054 14.1 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.13 EGB10623.1 - 0.024 14.2 0.0 0.16 11.5 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family DAO PF01266.24 EGB10623.1 - 0.051 13.1 0.5 2.6 7.5 0.1 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB10623.1 - 0.095 13.3 0.2 0.19 12.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGB10623.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SelR PF01641.18 EGB10624.1 - 1e-16 61.1 0.0 1.3e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EGB10624.1 - 0.095 12.9 0.1 1.3 9.3 0.1 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ring_hydroxyl_A PF00848.19 EGB10625.1 - 2.6e-30 106.0 0.2 5.1e-30 105.0 0.2 1.4 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EGB10625.1 - 7.7e-13 48.2 0.3 1.6e-12 47.2 0.3 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PhyH PF05721.13 EGB10626.1 - 1.1e-11 45.4 0.0 2.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF5536 PF17688.1 EGB10626.1 - 1.8 8.4 5.4 4.6 7.1 5.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5536) NAD_binding_10 PF13460.6 EGB10627.1 - 2.3e-20 73.3 1.0 3.1e-20 72.9 1.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGB10627.1 - 9.4e-05 22.1 1.5 0.00013 21.6 1.5 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGB10627.1 - 0.00059 19.4 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EGB10627.1 - 0.0028 17.8 0.1 0.01 15.9 0.1 1.8 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EGB10627.1 - 0.004 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGB10627.1 - 0.046 12.9 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjgF_endoribonc PF14588.6 EGB10628.1 - 2.7e-25 89.3 0.0 3.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EGB10628.1 - 1.2e-13 51.2 0.0 2.1e-13 50.4 0.0 1.4 1 1 0 1 1 1 1 Endoribonuclease L-PSP PHO4 PF01384.20 EGB10629.1 - 9e-109 363.6 20.3 1.2e-108 363.1 20.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family Bystin PF05291.11 EGB10630.1 - 3.4e-115 384.3 0.1 4.3e-115 384.0 0.1 1.1 1 0 0 1 1 1 1 Bystin BUD22 PF09073.10 EGB10630.1 - 1.9 7.7 11.1 2.9 7.1 11.1 1.2 1 0 0 1 1 1 0 BUD22 Peptidase_M15 PF01427.17 EGB10631.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase Peptidase_M3 PF01432.20 EGB10634.1 - 3.5e-20 72.7 0.0 1.4e-19 70.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.15 EGB10634.1 - 0.067 11.9 0.0 3.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase Peptidase_M91 PF14891.6 EGB10634.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Effector protein Coprogen_oxidas PF01218.18 EGB10635.1 - 1.2e-134 447.7 0.3 1.4e-134 447.4 0.3 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase LPD7 PF18821.1 EGB10635.1 - 0.073 13.2 0.1 0.67 10.1 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 ABC_tran PF00005.27 EGB10636.1 - 1.6e-19 70.8 0.0 2.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGB10636.1 - 1.6e-06 28.6 0.3 2.5e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB10636.1 - 7.8e-05 22.6 0.0 0.08 12.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB10636.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGB10636.1 - 0.00014 21.5 0.6 0.00041 20.0 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EGB10636.1 - 0.00025 21.5 0.0 0.0035 17.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB10636.1 - 0.00033 20.9 0.2 0.0036 17.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB10636.1 - 0.00095 18.8 0.2 0.0036 16.9 0.2 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB10636.1 - 0.0049 16.8 0.6 0.012 15.5 0.1 1.8 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 EGB10636.1 - 0.0064 16.7 0.1 0.013 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGB10636.1 - 0.0069 16.9 0.0 0.0095 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGB10636.1 - 0.0092 15.4 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EGB10636.1 - 0.011 16.0 0.2 0.022 15.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGB10636.1 - 0.014 15.1 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EGB10636.1 - 0.016 15.0 0.2 0.037 13.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EGB10636.1 - 0.02 13.9 0.2 0.03 13.3 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGB10636.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 EGB10636.1 - 0.049 14.2 0.3 0.11 13.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 EGB10636.1 - 0.057 13.0 0.1 0.085 12.4 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGB10636.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EGB10636.1 - 0.085 12.2 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGB10636.1 - 0.09 13.1 0.9 0.2 12.0 0.9 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGB10636.1 - 0.11 12.5 0.0 3.4 7.7 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 EGB10636.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB10636.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EGB10636.1 - 0.12 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EGB10636.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EGB10636.1 - 0.13 12.3 0.1 0.41 10.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 EGB10636.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 EGB10636.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 EGB10636.1 - 0.21 10.5 0.1 0.39 9.6 0.1 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 EGB10636.1 - 0.22 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EGB10636.1 - 0.22 11.9 0.0 0.32 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA helicase GGACT PF06094.12 EGB10637.1 - 1e-19 71.3 0.3 1.1e-19 71.2 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EGB10637.1 - 0.00088 19.6 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family NDK PF00334.19 EGB10638.1 - 2e-51 173.6 0.0 2.4e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Calreticulin PF00262.18 EGB10639.1 - 2.8e-122 408.1 5.9 3.2e-122 407.9 5.9 1.0 1 0 0 1 1 1 1 Calreticulin family PHM7_cyt PF14703.6 EGB10640.1 - 2.5e-09 37.6 0.0 2.5e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 EGB10640.1 - 1.6e-06 27.6 2.2 4.9e-06 26.1 2.2 1.8 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RRM_1 PF00076.22 EGB10640.1 - 0.00062 19.5 0.1 0.97 9.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Anoctamin PF04547.12 EGB10640.1 - 0.0025 16.7 1.7 0.0061 15.5 0.8 2.0 2 1 0 2 2 2 1 Calcium-activated chloride channel SET PF00856.28 EGB10640.1 - 0.027 14.9 0.1 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 SET domain zf-MYND PF01753.18 EGB10640.1 - 2.3 8.4 16.5 0.077 13.1 8.6 2.8 2 0 0 2 2 2 0 MYND finger PKcGMP_CC PF16808.5 EGB10641.1 - 0.17 11.8 0.3 0.5 10.3 0.3 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PV-1 PF06637.11 EGB10641.1 - 0.54 9.0 4.7 1.3 7.8 4.7 1.5 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ADIP PF11559.8 EGB10641.1 - 1.1 9.3 5.4 2.3 8.3 5.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ras PF00071.22 EGB10642.1 - 2.5e-47 160.5 0.0 3e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB10642.1 - 2.7e-30 105.0 0.0 3.7e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB10642.1 - 4.3e-10 39.3 0.0 6.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB10642.1 - 0.00063 19.8 0.0 0.0014 18.7 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGB10642.1 - 0.00072 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGB10642.1 - 0.0011 18.6 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB10642.1 - 0.019 14.9 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EGB10642.1 - 0.14 11.6 0.0 0.35 10.3 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AMP-binding PF00501.28 EGB10643.1 - 1e-90 304.4 0.0 1.3e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB10643.1 - 5.9e-18 65.6 2.1 1.3e-17 64.5 0.5 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_deac_1 PF01522.21 EGB10644.1 - 5.9e-17 61.7 0.0 7.9e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase zf-C3HC4 PF00097.25 EGB10645.1 - 2.5e-06 27.2 11.3 2.5e-06 27.2 11.3 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGB10645.1 - 8.2e-06 25.6 8.5 8.2e-06 25.6 8.5 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB10645.1 - 2.4e-05 24.6 10.6 2.4e-05 24.6 10.6 2.3 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EGB10645.1 - 0.0021 18.0 8.3 0.007 16.4 8.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Sina PF03145.16 EGB10645.1 - 0.0055 16.7 0.2 0.0055 16.7 0.2 1.7 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGB10645.1 - 0.006 16.4 10.8 0.006 16.4 10.8 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB10645.1 - 0.012 15.5 7.0 0.012 15.5 7.0 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGB10645.1 - 0.014 15.3 12.4 0.014 15.3 12.4 2.4 2 2 0 2 2 2 0 zinc-RING finger domain zf-Di19 PF05605.12 EGB10645.1 - 0.036 14.3 10.8 0.35 11.2 2.3 3.0 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 EGB10645.1 - 0.051 13.4 11.3 0.05 13.4 6.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2769 PF10967.8 EGB10645.1 - 4.8 7.9 13.7 0.11 13.2 5.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2769) zf-C3HC4_4 PF15227.6 EGB10645.1 - 4.8 7.4 13.5 1.9 8.7 9.1 2.5 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGB10645.1 - 6 7.0 14.4 3.7 7.6 9.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon Glyco_hydro_6 PF01341.17 EGB10646.1 - 1.7e-41 142.9 0.1 7.8e-31 107.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Ion_trans PF00520.31 EGB10646.1 - 2.7e-05 23.5 6.3 6.9e-05 22.2 6.3 1.7 1 0 0 1 1 1 1 Ion transport protein Ins145_P3_rec PF08709.11 EGB10646.1 - 0.0065 15.7 0.0 1.1 8.4 0.0 3.0 3 0 0 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF4064 PF13273.6 EGB10646.1 - 0.015 15.5 0.4 0.097 13.0 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) PI3_PI4_kinase PF00454.27 EGB10647.1 - 1.4e-37 129.9 0.0 1.8e-34 119.7 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGB10647.1 - 1.6e-16 59.8 0.0 3.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 FATC domain DUF4135 PF13575.6 EGB10647.1 - 0.022 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Aminotran_1_2 PF00155.21 EGB10649.1 - 5.6e-22 78.4 0.0 7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGB10649.1 - 3.8e-11 42.4 0.0 5.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase TP_methylase PF00590.20 EGB10650.1 - 1.3e-41 142.9 0.6 1.5e-41 142.6 0.6 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Esterase PF00756.20 EGB10651.1 - 4.1e-44 151.1 0.0 4.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EGB10651.1 - 1.6e-05 24.3 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EGB10651.1 - 0.00097 18.7 1.5 0.014 14.9 1.5 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EGB10651.1 - 0.0025 17.3 0.0 0.0054 16.2 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EGB10651.1 - 0.028 13.1 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 EGB10651.1 - 0.04 13.8 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 EGB10651.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB10651.1 - 0.14 12.7 10.4 0.21 12.2 10.4 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.25 EGB10653.1 - 2.9e-54 184.2 0.0 3.3e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10653.1 - 1.1e-26 93.7 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB10653.1 - 0.00042 19.7 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MCR_beta PF02241.18 EGB10653.1 - 0.085 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain TMEM191C PF15194.6 EGB10653.1 - 0.19 11.9 0.3 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 TMEM191C family EF-hand_7 PF13499.6 EGB10654.1 - 0.059 13.8 2.6 0.16 12.5 2.6 1.7 1 0 0 1 1 1 0 EF-hand domain pair Cript PF10235.9 EGB10656.1 - 2.3e-20 73.0 1.6 2.3e-20 73.0 1.6 1.5 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EGB10656.1 - 9e-05 22.4 7.8 0.0022 18.0 5.9 2.3 2 1 0 2 2 2 1 Double zinc ribbon DUF2039 PF10217.9 EGB10656.1 - 0.0016 18.8 6.4 0.0016 18.8 6.4 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zinc_ribbon_15 PF17032.5 EGB10656.1 - 0.0088 16.8 9.8 0.027 15.2 5.8 2.6 2 1 0 2 2 2 1 zinc-ribbon family zinc-ribbons_6 PF07191.12 EGB10656.1 - 0.012 15.6 8.5 0.053 13.5 3.9 2.2 2 0 0 2 2 2 0 zinc-ribbons zf-C3HC4_3 PF13920.6 EGB10656.1 - 0.033 14.0 10.8 0.17 11.8 7.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 EGB10656.1 - 0.053 13.3 12.3 1.7 8.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain PHF5 PF03660.14 EGB10656.1 - 0.21 11.8 8.5 0.17 12.1 5.7 2.1 2 1 0 2 2 2 0 PHF5-like protein DUF1272 PF06906.11 EGB10656.1 - 0.26 11.4 7.6 0.26 11.4 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) TF_Zn_Ribbon PF08271.12 EGB10656.1 - 3.3 7.3 9.7 40 3.8 0.1 3.4 2 1 0 2 2 2 0 TFIIB zinc-binding Gin PF10764.9 EGB10656.1 - 5.8 6.9 12.7 1.4 9.0 0.2 3.3 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin WD40 PF00400.32 EGB10657.1 - 2e-52 174.0 21.5 5.1e-07 30.3 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB10657.1 - 4.1e-12 46.2 0.5 0.022 15.0 0.1 5.0 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB10657.1 - 5.8e-08 32.1 6.5 0.077 11.9 0.0 6.1 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EGB10657.1 - 0.00068 19.3 4.7 0.15 11.6 0.6 2.5 2 1 0 2 2 2 2 PQQ-like domain LRR_4 PF12799.7 EGB10658.1 - 3.3e-06 27.3 1.7 1.9 9.0 0.2 4.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB10658.1 - 0.00029 20.5 0.0 4.3 7.2 0.1 4.2 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 EGB10658.1 - 0.0075 16.7 2.1 1.3 9.8 0.1 4.8 3 3 1 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 EGB10658.1 - 0.33 11.1 5.0 6 7.2 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Diphthami_syn_2 PF01902.17 EGB10660.1 - 1.1e-34 119.9 0.0 4.7e-34 117.8 0.0 1.7 1 1 0 1 1 1 1 Diphthamide synthase tRNA_Me_trans PF03054.16 EGB10660.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.13 EGB10660.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Ank_2 PF12796.7 EGB10661.1 - 8.7e-12 45.5 0.0 1e-11 45.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10661.1 - 1.6e-11 44.5 0.0 5.9e-05 23.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB10661.1 - 2.7e-10 40.3 0.3 1.6e-05 25.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10661.1 - 1.9e-09 37.0 0.0 5.1e-05 23.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGB10661.1 - 5e-08 33.0 0.1 1.9e-05 24.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat FKBP_C PF00254.28 EGB10662.1 - 1e-18 67.5 0.0 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Abhydrolase_3 PF07859.13 EGB10663.1 - 1.9e-48 165.1 0.4 2.2e-48 164.9 0.4 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGB10663.1 - 1.9e-09 37.0 0.4 1.6e-08 33.9 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 EGB10663.1 - 0.0074 15.8 2.3 0.077 12.5 0.5 2.3 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EGB10663.1 - 0.14 11.6 0.0 5.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 EGB10663.1 - 0.45 9.0 0.8 0.63 8.5 0.1 1.4 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Acyl-CoA_dh_M PF02770.19 EGB10665.1 - 5.6e-07 29.7 0.2 8e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGB10665.1 - 0.016 15.5 1.0 0.016 15.5 1.0 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain LVIVD PF08309.11 EGB10667.1 - 0.0012 18.1 0.1 0.19 11.1 0.3 3.6 3 0 0 3 3 3 1 LVIVD repeat AMP-binding PF00501.28 EGB10668.1 - 6.6e-23 81.0 0.0 7.8e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Trypsin_2 PF13365.6 EGB10669.1 - 4e-25 89.5 2.3 4e-25 89.5 2.3 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGB10669.1 - 5.2e-10 39.5 0.0 9.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EGB10669.1 - 1.8e-07 31.4 0.2 3.6e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGB10669.1 - 0.0002 21.6 0.1 0.00038 20.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EGB10669.1 - 0.0016 18.2 0.2 0.005 16.7 0.2 1.9 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 EGB10669.1 - 0.0043 15.8 0.9 0.0059 15.3 0.9 1.1 1 0 0 1 1 1 1 Peptidase S46 Peptidase_S39 PF02122.15 EGB10669.1 - 0.075 12.5 0.0 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Peptidase S39 PDZ_3 PF17815.1 EGB10669.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 PDZ domain DSBA PF01323.20 EGB10670.1 - 5.2e-06 26.4 0.0 9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Glyco_transf_28 PF03033.20 EGB10671.1 - 1.2e-16 61.1 0.0 3.3e-16 59.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGB10671.1 - 1.4e-06 27.4 0.1 3.1e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EGB10671.1 - 0.21 11.5 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PTPA PF03095.15 EGB10672.1 - 6.6e-57 193.3 0.0 7.8e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MINDY_DUB PF04424.13 EGB10673.1 - 1.6e-26 92.6 0.0 2.4e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase adh_short PF00106.25 EGB10674.1 - 4.9e-47 159.9 0.1 5.8e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB10674.1 - 2e-30 106.1 0.4 2.6e-30 105.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB10674.1 - 1e-21 77.7 1.4 1.3e-21 77.3 1.4 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGB10674.1 - 7.8e-05 22.6 2.6 7.8e-05 22.6 2.6 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EGB10674.1 - 0.0021 17.7 1.6 0.0033 17.0 1.6 1.3 1 0 0 1 1 1 1 NmrA-like family Y_phosphatase PF00102.27 EGB10674.1 - 0.0055 16.3 0.0 0.0075 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TrkA_N PF02254.18 EGB10674.1 - 0.0084 16.4 0.2 0.013 15.7 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 EGB10674.1 - 0.022 14.2 0.1 0.034 13.6 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGB10674.1 - 0.028 13.6 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EGB10674.1 - 0.028 14.3 0.4 0.05 13.5 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGB10674.1 - 0.041 14.0 0.3 0.089 13.0 0.1 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 EGB10674.1 - 0.043 13.2 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 EGB10674.1 - 0.056 12.8 0.1 0.14 11.5 0.0 1.6 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox PF00070.27 EGB10674.1 - 0.06 13.9 0.3 0.1 13.2 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 EGB10674.1 - 0.061 12.4 0.4 0.1 11.7 0.2 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 EGB10674.1 - 0.073 13.3 0.3 0.12 12.7 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Myosin_head PF00063.21 EGB10675.1 - 7e-197 655.8 0.0 1.2e-196 654.9 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EGB10675.1 - 6.5e-10 38.7 0.2 1.4e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain WW PF00397.26 EGB10675.1 - 0.0082 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 WW domain AAA_22 PF13401.6 EGB10675.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EGB10675.1 - 0.048 13.2 0.0 6.5 6.3 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EGB10675.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain EF-hand_1 PF00036.32 EGB10676.1 - 9.2e-11 40.5 5.3 0.00031 20.1 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EGB10676.1 - 2.8e-10 39.3 7.9 0.0062 16.4 0.0 6.5 8 0 0 8 8 8 3 EF-hand domain EF-hand_7 PF13499.6 EGB10676.1 - 4.9e-09 36.5 2.6 0.036 14.5 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB10676.1 - 5.7e-06 25.6 7.5 7.6e-05 22.0 0.0 4.6 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 EGB10676.1 - 3e-05 23.8 1.1 0.066 13.1 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain pair EamA PF00892.20 EGB10677.1 - 8.9e-08 32.4 4.1 8.9e-08 32.4 4.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family Pkinase PF00069.25 EGB10678.1 - 9.4e-65 218.6 0.0 1.1e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10678.1 - 2.9e-45 154.6 0.0 3.4e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB10678.1 - 1.1e-05 24.9 0.1 0.00044 19.7 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB10678.1 - 0.00018 20.4 0.0 0.00035 19.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGB10678.1 - 0.0043 16.4 0.2 0.0088 15.4 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB10678.1 - 0.022 14.7 2.5 0.041 13.8 0.2 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Gln_deamidase_2 PF18626.1 EGB10678.1 - 0.039 14.2 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutaminase Haspin_kinase PF12330.8 EGB10678.1 - 0.058 12.3 0.1 0.23 10.3 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain SGL PF08450.12 EGB10679.1 - 7.5e-17 61.7 0.0 1.1e-16 61.2 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EGB10679.1 - 5.8e-05 23.1 0.0 0.029 14.5 0.0 2.4 2 0 0 2 2 2 2 Strictosidine synthase NHL PF01436.21 EGB10679.1 - 0.091 12.8 1.4 0.91 9.7 0.0 3.0 3 0 0 3 3 3 0 NHL repeat PALP PF00291.25 EGB10681.1 - 1.4e-75 254.4 8.7 1.4e-75 254.4 8.7 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGB10681.1 - 1.5e-34 117.6 0.0 1.8e-18 66.1 0.1 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Peptidase_M48 PF01435.18 EGB10683.1 - 1.5e-18 67.3 0.2 1.4e-15 57.6 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EGB10683.1 - 0.074 12.2 0.0 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 BlaR1 peptidase M56 Abhydrolase_1 PF00561.20 EGB10684.1 - 8.5e-21 74.7 0.1 4.3e-20 72.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB10684.1 - 5.4e-20 71.7 0.2 1.9e-19 69.9 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGB10684.1 - 2.3e-18 67.6 13.8 3.4e-18 67.0 13.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EGB10684.1 - 5e-07 30.1 0.0 1.1e-06 29.0 0.1 1.5 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 EGB10684.1 - 5.3e-05 23.2 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.13 EGB10684.1 - 0.00017 21.5 0.1 0.09 12.6 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 EGB10684.1 - 0.0009 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 EGB10684.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGB10684.1 - 0.0027 17.5 0.0 0.0063 16.3 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_8 PF06259.12 EGB10684.1 - 0.003 17.2 0.3 0.0059 16.3 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase DUF915 PF06028.11 EGB10684.1 - 0.0039 16.6 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Acyl_transf_1 PF00698.21 EGB10684.1 - 0.042 13.4 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Acyl transferase domain UPF0227 PF05728.12 EGB10684.1 - 0.053 13.5 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) ARL2_Bind_BART PF11527.8 EGB10685.1 - 0.00038 20.5 1.2 0.00079 19.5 0.2 2.0 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART CDC45 PF02724.14 EGB10685.1 - 0.055 11.8 0.6 0.1 10.9 0.6 1.3 1 0 0 1 1 1 0 CDC45-like protein TPT PF03151.16 EGB10686.1 - 1.6e-14 54.0 7.5 2e-14 53.7 7.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EGB10686.1 - 0.0059 15.9 3.0 0.011 15.0 3.0 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB10686.1 - 0.0097 16.1 5.5 0.0097 16.1 5.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3054 PF11255.8 EGB10686.1 - 2 8.9 9.5 0.082 13.4 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) His_Phos_1 PF00300.22 EGB10687.1 - 1.3e-30 106.5 1.1 2.4e-23 82.8 0.4 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) COX15-CtaA PF02628.15 EGB10688.1 - 3e-101 338.7 7.1 3.4e-101 338.5 7.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosomal_L4 PF00573.22 EGB10689.1 - 2.8e-49 167.4 0.4 3.5e-49 167.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF4148 PF13663.6 EGB10689.1 - 0.035 14.3 7.0 0.21 11.8 7.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) Transposase_21 PF02992.14 EGB10689.1 - 0.082 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 SelR PF01641.18 EGB10690.1 - 5.1e-39 133.1 0.1 5.4e-39 133.0 0.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EGB10690.1 - 0.0044 17.2 1.3 0.019 15.2 1.3 1.8 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_recom PF13408.6 EGB10690.1 - 0.022 15.3 1.4 0.2 12.2 0.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain HECT_2 PF09814.9 EGB10690.1 - 0.079 11.8 0.5 1.7 7.4 0.0 2.0 1 1 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-LSD1 PF06943.12 EGB10690.1 - 0.69 9.8 8.8 2.3 8.1 0.5 2.6 2 0 0 2 2 2 0 LSD1 zinc finger Sulfotransfer_2 PF03567.14 EGB10691.1 - 4.2e-08 33.4 0.0 9.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family DHC_N2 PF08393.13 EGB10691.1 - 0.0024 17.1 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EGB10691.1 - 0.0092 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dus PF01207.17 EGB10692.1 - 1e-47 162.8 0.0 1.5e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PDZ_6 PF17820.1 EGB10693.1 - 0.1 12.5 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 PDZ domain GDA1_CD39 PF01150.17 EGB10694.1 - 5.6e-86 288.8 0.0 7.3e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Methyltransf_25 PF13649.6 EGB10695.1 - 1.3e-12 48.3 0.0 1.7e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB10695.1 - 6.6e-11 42.2 0.0 7.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB10695.1 - 1.2e-10 41.9 0.0 1.8e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGB10695.1 - 3.1e-10 39.9 0.1 3.4e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB10695.1 - 3.3e-08 33.3 0.0 4.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGB10695.1 - 7.4e-07 29.2 0.1 9.2e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB10695.1 - 3.4e-06 27.0 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EGB10695.1 - 6.7e-06 26.1 0.0 7.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 EGB10695.1 - 1e-05 25.0 0.1 1.1e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 EGB10695.1 - 4.2e-05 23.3 0.2 5.2e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 EGB10695.1 - 0.00024 20.1 0.0 0.0003 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 EGB10695.1 - 0.00034 21.3 0.0 0.00046 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB10695.1 - 0.00041 19.7 0.0 0.00046 19.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 EGB10695.1 - 0.00046 20.0 0.1 0.00055 19.7 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Rsm22 PF09243.10 EGB10695.1 - 0.0007 18.9 0.0 0.00087 18.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 EGB10695.1 - 0.00078 19.5 0.1 0.001 19.1 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGB10695.1 - 0.0015 19.5 0.1 0.0021 19.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EGB10695.1 - 0.0015 18.2 0.2 0.004 16.9 0.2 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.19 EGB10695.1 - 0.01 15.6 0.5 0.024 14.4 0.5 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EGB10695.1 - 0.013 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 EGB10695.1 - 0.013 15.0 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.26 EGB10695.1 - 0.017 15.1 0.3 0.023 14.7 0.3 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_2 PF00891.18 EGB10695.1 - 0.022 14.0 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EGB10695.1 - 0.028 14.2 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 EGB10695.1 - 0.052 12.9 0.0 0.075 12.4 0.0 1.3 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 EGB10695.1 - 0.071 12.9 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.20 EGB10695.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.13 EGB10695.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 FHA PF00498.26 EGB10696.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 FHA domain PLU-1 PF08429.11 EGB10696.1 - 0.19 10.9 0.0 0.19 10.9 0.0 2.2 2 1 0 2 2 2 0 PLU-1-like protein HlyD_D4 PF16572.5 EGB10696.1 - 2.7 7.9 6.6 0.59 10.0 1.5 2.6 2 0 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB PMSR PF01625.21 EGB10697.1 - 1.4e-34 119.5 0.1 2e-34 119.0 0.1 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DnaJ PF00226.31 EGB10699.1 - 6.3e-22 77.5 0.5 6.3e-22 77.5 0.5 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ-X PF14308.6 EGB10699.1 - 1.2e-19 70.7 0.0 2.2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing HECT PF00632.25 EGB10700.1 - 4.3e-27 95.4 0.0 4.7e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TPR_12 PF13424.6 EGB10701.1 - 5.5e-28 97.1 38.0 1.6e-10 41.1 0.2 6.0 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGB10701.1 - 7.1e-19 67.1 53.6 3.6e-05 23.5 0.2 9.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGB10701.1 - 1.2e-06 28.1 20.5 0.16 12.0 0.5 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10701.1 - 2.5e-06 27.3 3.1 0.078 13.2 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10701.1 - 0.036 14.2 33.8 1 9.6 0.1 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGB10701.1 - 0.19 12.5 0.2 0.19 12.5 0.2 10.9 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB10701.1 - 1.5 8.8 15.2 7.4 6.6 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat ASCH PF04266.14 EGB10702.1 - 3.8e-06 27.4 0.0 4.1e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 ASCH domain Ribosomal_S5 PF00333.20 EGB10703.1 - 1.4e-18 66.6 0.6 1.4e-18 66.6 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGB10703.1 - 1.1e-15 56.8 0.1 1.7e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF4548 PF15081.6 EGB10704.1 - 0.043 13.6 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4548) Methyltransf_24 PF13578.6 EGB10705.1 - 8.5e-07 30.0 0.1 3.2e-06 28.1 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Histone_H2A_C PF16211.5 EGB10706.1 - 8.3e-20 70.2 1.4 2e-19 69.0 1.4 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB10706.1 - 5.1e-12 46.3 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB10706.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2OG-FeII_Oxy_3 PF13640.6 EGB10707.1 - 4e-09 37.2 0.0 6.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC2_membrane PF01061.24 EGB10709.1 - 5.3e-68 228.6 49.8 2.6e-35 121.8 26.3 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGB10709.1 - 2.9e-32 112.0 0.0 4.8e-16 59.5 0.0 2.2 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 EGB10709.1 - 4.9e-05 23.0 0.0 4.9e-05 23.0 0.0 2.8 3 0 0 3 3 3 1 Plant PDR ABC transporter associated AAA_16 PF13191.6 EGB10709.1 - 0.0027 18.1 0.3 0.52 10.7 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EGB10709.1 - 0.0066 16.3 0.3 0.43 10.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGB10709.1 - 0.022 15.2 0.1 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 EGB10709.1 - 0.054 12.6 47.1 0.07 12.2 22.4 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein NTPase_1 PF03266.15 EGB10709.1 - 0.21 11.5 0.4 7.1 6.5 0.0 2.7 3 0 0 3 3 3 0 NTPase PDR_CDR PF06422.12 EGB10709.1 - 0.37 10.7 0.0 0.37 10.7 0.0 3.0 3 0 0 3 3 3 0 CDR ABC transporter AAA_29 PF13555.6 EGB10709.1 - 0.48 10.2 1.5 7.1 6.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_transf_20 PF00982.21 EGB10711.1 - 8e-168 559.0 0.0 9.9e-168 558.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGB10711.1 - 1.9e-54 184.2 0.0 3.1e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 EGB10711.1 - 0.00071 19.2 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGB10711.1 - 0.017 15.1 0.2 0.04 13.9 0.2 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 COPIIcoated_ERV PF07970.12 EGB10712.1 - 1e-63 215.2 0.0 1.4e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGB10712.1 - 1.1e-20 73.8 0.0 1.8e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SNF2_N PF00176.23 EGB10713.1 - 1.9e-18 66.3 0.0 2.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain RIBIOP_C PF04950.12 EGB10714.1 - 1.2e-73 248.1 0.0 1.6e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGB10714.1 - 3e-24 84.9 0.0 5.6e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EGB10714.1 - 4.8e-05 23.0 0.0 0.0077 15.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGB10714.1 - 0.00025 21.3 0.0 0.00055 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB10714.1 - 0.00029 21.0 0.2 0.0031 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGB10714.1 - 0.00038 21.0 0.1 0.02 15.4 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EGB10714.1 - 0.0011 19.4 0.0 0.0011 19.4 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EGB10714.1 - 0.0047 16.1 0.0 0.0095 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EGB10714.1 - 0.0054 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGB10714.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGB10714.1 - 0.021 15.3 0.1 0.066 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain Adeno_IVa2 PF02456.15 EGB10714.1 - 0.024 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein cobW PF02492.19 EGB10714.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGB10714.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 EGB10714.1 - 0.042 12.9 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EGB10714.1 - 0.044 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGB10714.1 - 0.051 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.9 EGB10714.1 - 0.067 12.9 0.1 0.65 9.7 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EGB10714.1 - 0.067 13.6 0.0 0.38 11.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 EGB10714.1 - 0.1 12.7 0.1 0.35 11.0 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 EGB10714.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGB10714.1 - 0.18 11.7 0.1 0.57 10.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 EGB10714.1 - 0.19 11.6 0.2 0.33 10.8 0.2 1.4 1 0 0 1 1 1 0 NTPase G-alpha PF00503.20 EGB10714.1 - 0.23 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SNF2_N PF00176.23 EGB10715.1 - 6.6e-22 77.7 0.0 4.6e-21 74.9 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB10715.1 - 2e-09 37.7 0.0 3.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB10715.1 - 0.00014 21.9 0.0 0.01 15.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB10715.1 - 0.057 13.2 0.0 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase DnaJ PF00226.31 EGB10716.1 - 9e-12 44.9 0.3 2.2e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 EGB10716.1 - 2.2e-10 41.0 8.1 1.8e-08 34.8 1.6 2.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10716.1 - 2.3e-10 40.8 4.2 4.3e-07 30.4 0.7 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10716.1 - 2.5e-08 33.5 3.7 0.0051 17.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB10716.1 - 1.4e-07 31.6 3.2 6.4e-05 23.2 0.6 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB10716.1 - 1.8e-05 24.9 10.5 0.023 15.2 1.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat TPR_1 PF00515.28 EGB10716.1 - 0.0062 16.3 0.9 1.1 9.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10716.1 - 0.017 15.2 0.1 0.017 15.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat AATF-Che1 PF13339.6 EGB10716.1 - 0.047 14.4 0.7 0.16 12.7 0.7 1.8 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TMF_TATA_bd PF12325.8 EGB10716.1 - 0.052 13.8 5.3 0.031 14.5 2.9 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 EGB10716.1 - 0.15 11.2 6.4 0.31 10.1 6.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cwf_Cwc_15 PF04889.12 EGB10716.1 - 0.44 10.2 32.4 0.45 10.2 13.4 2.6 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Spc7 PF08317.11 EGB10716.1 - 9.5 5.0 8.6 16 4.3 8.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein SKIP_SNW PF02731.15 EGB10717.1 - 1.5e-66 223.0 0.2 1.5e-66 223.0 0.2 1.8 2 0 0 2 2 2 1 SKIP/SNW domain Thx PF17070.5 EGB10718.1 - 0.0013 18.8 4.5 0.0019 18.2 4.5 1.2 1 0 0 1 1 1 1 30S ribosomal protein Thx RPS31 PF17067.5 EGB10718.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S31e REJ PF02010.15 EGB10719.1 - 7.6e-18 64.5 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 REJ domain Corona_nucleoca PF00937.18 EGB10719.1 - 0.23 10.5 3.1 0.43 9.6 3.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ASCH PF04266.14 EGB10720.1 - 0.00053 20.5 0.2 0.0019 18.8 0.1 2.0 2 0 0 2 2 2 1 ASCH domain RCC1 PF00415.18 EGB10721.1 - 2.7e-21 75.9 19.1 7.4e-08 32.9 0.3 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB10721.1 - 1.7e-13 50.0 30.5 2.4e-05 24.0 1.7 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Mpv17_PMP22 PF04117.12 EGB10723.1 - 3.6e-09 36.7 0.5 6.8e-09 35.8 0.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family EF-hand_1 PF00036.32 EGB10724.1 - 5.4e-15 53.7 2.3 0.00053 19.3 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB10724.1 - 2.3e-12 45.8 1.8 0.0017 18.1 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EGB10724.1 - 7.2e-11 41.1 2.0 0.025 14.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGB10724.1 - 3.4e-10 39.6 2.0 0.0084 15.9 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 EGB10724.1 - 8.3e-10 39.0 3.6 3.9e-06 27.2 0.3 3.1 2 1 0 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 EGB10724.1 - 0.0094 16.1 0.7 0.63 10.3 0.0 2.9 3 0 0 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 EGB10724.1 - 0.055 13.4 0.6 3 7.7 0.0 2.4 3 0 0 3 3 3 0 Caleosin related protein Myosin_head PF00063.21 EGB10725.1 - 5.6e-144 480.9 0.0 6.9e-144 480.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB10725.1 - 0.065 13.6 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Herpes_Helicase PF02689.14 EGB10725.1 - 0.076 10.9 0.1 0.11 10.4 0.1 1.1 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 EGB10725.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EGB10725.1 - 0.2 11.2 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NAD_binding_2 PF03446.15 EGB10726.1 - 8.5e-32 110.5 1.2 1.2e-31 110.1 1.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGB10726.1 - 4e-14 52.9 0.6 8.4e-14 51.9 0.6 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGB10726.1 - 1.8e-06 28.4 0.0 4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGB10726.1 - 0.01 15.9 0.5 0.019 15.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EGB10726.1 - 0.028 14.3 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EGB10726.1 - 0.038 13.6 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Tyr-DNA_phospho PF06087.12 EGB10727.1 - 1.7e-19 70.1 0.0 2.2e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 EGB10727.1 - 0.00059 19.6 35.3 0.016 15.1 4.1 5.6 5 0 0 5 5 5 4 Ubiquitin interaction motif PLDc_2 PF13091.6 EGB10727.1 - 0.0061 16.4 0.0 0.054 13.4 0.0 2.4 3 0 0 3 3 3 1 PLD-like domain SPRY PF00622.28 EGB10728.1 - 4.4e-13 49.4 0.0 7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain HMG_box PF00505.19 EGB10728.1 - 1.9e-05 25.0 0.1 3.3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB10728.1 - 0.00062 20.3 0.1 0.00095 19.7 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain Nramp PF01566.18 EGB10729.1 - 2.2e-37 128.9 16.2 4e-37 128.0 16.2 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF1279 PF06916.13 EGB10729.1 - 4.3e-20 72.0 1.8 4.9e-20 71.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) WW PF00397.26 EGB10729.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 WW domain Sulfatase PF00884.23 EGB10730.1 - 2.5e-60 204.5 0.0 4.5e-60 203.6 0.0 1.4 2 0 0 2 2 2 1 Sulfatase Sulfatase_C PF14707.6 EGB10730.1 - 1.7e-27 96.6 0.0 2.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 EGB10730.1 - 0.0017 18.0 0.0 0.03 13.9 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase ADP_ribosyl_GH PF03747.14 EGB10731.1 - 1.1e-39 136.9 10.3 1.1e-39 136.9 10.3 2.3 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase MFS_1 PF07690.16 EGB10731.1 - 7.4e-23 81.0 64.9 9.8e-17 60.9 37.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Stealth_CR4 PF17103.5 EGB10731.1 - 9.6e-20 70.2 0.6 1.7e-19 69.4 0.6 1.4 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 EGB10731.1 - 4.7e-17 61.6 0.8 9.9e-17 60.6 0.8 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 EGB10731.1 - 2.2e-05 24.8 12.6 4.3e-05 23.9 12.6 1.5 1 0 0 1 1 1 1 LNR domain Acetyltransf_1 PF00583.25 EGB10732.1 - 2.1e-11 44.1 0.0 2.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGB10732.1 - 1.8e-07 31.0 0.1 2.5e-06 27.4 0.0 2.0 1 1 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 EGB10732.1 - 5.1e-06 26.4 0.1 6.6e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB10732.1 - 6.7e-06 26.4 0.0 1.1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGB10732.1 - 0.0058 16.7 0.1 0.0085 16.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DAGAT PF03982.13 EGB10733.1 - 1.4e-35 122.6 0.0 1.8e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Pro_isomerase PF00160.21 EGB10734.1 - 4.2e-05 23.9 0.0 9.4e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD JmjC PF02373.22 EGB10735.1 - 0.0057 17.1 0.0 0.59 10.6 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGB10735.1 - 0.0082 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain EF-hand_5 PF13202.6 EGB10735.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 EF hand Cupin_8 PF13621.6 EGB10735.1 - 0.049 13.3 0.0 0.3 10.8 0.0 2.0 1 1 0 1 1 1 0 Cupin-like domain DUF4604 PF15377.6 EGB10735.1 - 0.052 14.0 0.0 0.081 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Ribosomal_L39 PF00832.20 EGB10735.1 - 0.16 11.6 0.2 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L39 protein MFS_1 PF07690.16 EGB10736.1 - 5.6e-13 48.5 27.5 5.6e-13 48.5 27.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGB10736.1 - 0.0004 19.1 4.4 0.18 10.3 0.3 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF1940 PF09155.10 EGB10737.1 - 0.066 13.3 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) ArnB_C PF18677.1 EGB10737.1 - 0.18 11.9 0.1 0.65 10.1 0.0 1.8 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain DHH PF01368.20 EGB10738.1 - 4.7e-09 36.4 0.0 7.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.14 EGB10738.1 - 1.7e-07 31.5 0.0 2.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain Peptidase_M16_C PF05193.21 EGB10739.1 - 5.2e-41 140.7 0.0 7.5e-21 75.0 0.0 2.7 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGB10739.1 - 2.5e-18 66.5 0.0 4.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) BMC PF00936.19 EGB10739.1 - 0.077 13.0 0.0 4 7.5 0.0 3.0 3 0 0 3 3 3 0 BMC domain Sedlin_N PF04628.13 EGB10740.1 - 9.6e-21 74.3 0.0 1.1e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGB10740.1 - 0.017 15.0 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Sybindin-like family 2-oxogl_dehyd_N PF16078.5 EGB10740.1 - 0.043 13.4 0.7 0.47 10.1 0.1 2.4 1 1 1 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus Histone_H2A_C PF16211.5 EGB10741.1 - 8.3e-20 70.2 1.4 2e-19 69.0 1.4 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB10741.1 - 5.1e-12 46.3 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB10741.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 EGB10742.1 - 7.9e-21 73.5 1.4 2.2e-20 72.1 1.4 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB10742.1 - 1e-11 45.3 0.0 1.2e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB10742.1 - 0.0015 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Meckelin PF09773.9 EGB10743.1 - 1.8e-23 82.6 2.9 1.9e-23 82.6 2.9 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) E3_UbLigase_R4 PF13764.6 EGB10744.1 - 1.3e-86 291.6 0.0 3.6e-86 290.1 0.0 1.6 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 DOT1 PF08123.13 EGB10744.1 - 4.5e-13 49.2 0.0 7.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 zf-UBR PF02207.20 EGB10744.1 - 3e-07 30.5 12.4 3e-07 30.5 12.4 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Nop14 PF04147.12 EGB10744.1 - 1.1 7.3 40.2 0.02 13.1 14.7 2.2 2 0 0 2 2 2 0 Nop14-like family zf-ribbon_3 PF13248.6 EGB10744.1 - 3.2 7.3 6.5 1.5 8.4 2.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain AIG2_2 PF13772.6 EGB10745.1 - 1.4e-05 25.4 0.0 2.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Nucleotid_trans PF03407.16 EGB10746.1 - 0.00074 19.6 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Peptidase_G2 PF11962.8 EGB10746.1 - 0.0059 16.0 0.0 0.68 9.3 0.1 2.2 1 1 1 2 2 2 2 Peptidase_G2, IMC autoproteolytic cleavage domain Kelch_4 PF13418.6 EGB10747.1 - 1.2e-32 111.7 18.3 4.3e-08 33.0 0.3 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGB10747.1 - 6.7e-25 86.8 27.5 2.7e-07 30.7 0.5 7.1 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGB10747.1 - 5.2e-23 80.6 5.8 2.1e-07 30.8 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGB10747.1 - 7.6e-22 76.6 9.3 2.4e-09 36.6 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EGB10747.1 - 1.4e-20 72.8 0.3 7.7e-06 26.0 0.0 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGB10747.1 - 6.4e-17 60.8 3.3 0.00013 21.8 0.0 6.0 6 1 0 6 6 6 4 Kelch motif MFS_1_like PF12832.7 EGB10748.1 - 2.1e-46 158.6 14.5 3.1e-46 158.0 14.5 1.3 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGB10748.1 - 1.4e-16 60.4 89.3 3.5e-10 39.3 42.5 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Urocanase_C PF17392.2 EGB10750.1 - 6.3e-79 264.0 7.4 1.3e-78 263.0 7.4 1.5 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 EGB10750.1 - 3.5e-77 258.8 0.0 8.6e-77 257.5 0.0 1.6 2 0 0 2 2 2 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 EGB10750.1 - 1e-49 167.5 0.4 5.3e-49 165.1 0.1 2.3 3 0 0 3 3 3 1 Urocanase N-terminal domain CheR PF01739.18 EGB10750.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Pep_deformylase PF01327.21 EGB10751.1 - 2.5e-34 118.2 0.0 2.8e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Shadoo PF14999.6 EGB10751.1 - 2.1 8.5 6.4 0.42 10.7 1.7 1.9 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Dynein_light PF01221.18 EGB10752.1 - 5e-21 74.8 0.1 5.7e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 SH3_9 PF14604.6 EGB10753.1 - 3.1e-07 30.1 0.0 5.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EGB10753.1 - 6.6e-07 29.3 0.0 0.013 15.5 0.1 2.4 2 0 0 2 2 2 2 WW domain SH3_2 PF07653.17 EGB10753.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGB10753.1 - 0.0013 18.3 0.2 0.0061 16.2 0.2 2.0 1 1 0 1 1 1 1 SH3 domain Striatin PF08232.12 EGB10753.1 - 3.6 8.2 14.1 1.5 9.4 3.0 3.4 3 0 0 3 3 3 0 Striatin family TPR_1 PF00515.28 EGB10754.1 - 6.8e-07 28.8 6.5 0.2 11.5 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10754.1 - 3.2e-05 23.7 20.8 0.52 10.6 0.7 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10754.1 - 0.00064 20.0 18.8 0.44 10.9 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat SH3_3 PF08239.11 EGB10754.1 - 0.0008 19.6 0.3 0.0021 18.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain Vpu PF00558.19 EGB10754.1 - 0.0036 17.0 0.1 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 Vpu protein TPR_8 PF13181.6 EGB10754.1 - 0.019 15.1 6.8 23 5.5 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PGM_PMM_IV PF00408.20 EGB10754.1 - 0.038 14.2 1.8 0.32 11.2 0.1 3.5 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain TPR_17 PF13431.6 EGB10754.1 - 0.075 13.4 0.2 7.2 7.2 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Kinesin PF00225.23 EGB10755.1 - 4.5e-79 265.8 0.0 5.2e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB10755.1 - 4.7e-09 36.3 0.0 2.4e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Microtubule binding Pkinase_Tyr PF07714.17 EGB10756.1 - 6.5e-24 84.6 0.0 7.6e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB10756.1 - 9.2e-24 84.2 0.0 1.2e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGB10756.1 - 0.00098 19.1 0.3 0.43 10.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB10756.1 - 0.0025 17.2 0.0 0.003 16.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB10756.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB10756.1 - 0.18 10.5 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Sterol_MT_C PF08498.10 EGB10757.1 - 1.2e-15 57.5 0.9 3e-15 56.3 0.2 1.9 2 0 0 2 2 2 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGB10757.1 - 1.9e-09 38.1 0.0 3.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB10757.1 - 1.4e-07 32.1 0.0 2.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB10757.1 - 4.1e-07 30.0 0.0 6.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10757.1 - 1e-06 29.4 0.0 1.9e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB10757.1 - 5.6e-06 25.8 0.0 8.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EGB10757.1 - 8.9e-06 25.6 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB10757.1 - 0.048 13.0 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family U-box PF04564.15 EGB10758.1 - 3.2e-25 88.1 0.3 3.6e-25 87.9 0.3 1.0 1 0 0 1 1 1 1 U-box domain DUF4690 PF15756.5 EGB10758.1 - 0.074 13.7 0.1 0.088 13.4 0.1 1.1 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Helicase_C_2 PF13307.6 EGB10759.1 - 3.7e-50 170.4 0.0 5.8e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGB10759.1 - 2.6e-39 134.7 0.0 3.6e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 EGB10759.1 - 0.008 16.0 0.2 0.062 13.1 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 EGB10759.1 - 0.066 12.8 0.6 0.34 10.5 0.5 2.1 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 EGB10759.1 - 0.067 13.2 0.0 0.71 9.9 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HNF_C PF09354.10 EGB10760.1 - 0.2 12.7 0.0 0.62 11.1 0.0 1.8 1 0 0 1 1 1 0 HNF3 C-terminal domain HMG_box PF00505.19 EGB10761.1 - 2.1e-25 88.9 3.2 1.3e-17 63.9 0.1 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB10761.1 - 1e-14 54.8 0.6 2.8e-06 27.8 0.1 2.2 2 0 0 2 2 2 2 HMG-box domain THOC7 PF05615.13 EGB10762.1 - 2.9e-14 53.5 3.9 7.6e-14 52.1 3.9 1.7 1 0 0 1 1 1 1 Tho complex subunit 7 Mpv17_PMP22 PF04117.12 EGB10762.1 - 3.6e-09 36.7 2.8 5.2e-09 36.2 0.1 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family TPR_19 PF14559.6 EGB10762.1 - 8e-05 23.1 2.2 0.0033 17.9 0.1 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB10762.1 - 1.1 9.8 3.1 1.3 9.6 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB10762.1 - 4.2 7.6 7.3 10 6.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Spc7 PF08317.11 EGB10762.1 - 8.5 5.2 9.1 8.3 5.2 0.1 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein GATase_5 PF13507.6 EGB10763.1 - 1.5e-90 302.8 0.0 2.3e-90 302.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGB10763.1 - 2.5e-36 125.2 7.7 2.5e-20 73.2 0.3 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGB10763.1 - 4.8e-16 58.8 0.0 9.6e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGB10763.1 - 1.4e-10 41.5 0.0 2.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EGB10763.1 - 0.0013 19.4 0.4 0.0013 19.4 0.4 3.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain AMP-binding PF00501.28 EGB10764.1 - 2.3e-84 283.4 0.3 3e-84 283.1 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 EGB10764.1 - 0.12 12.5 0.0 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) adh_short PF00106.25 EGB10765.1 - 9.4e-48 162.3 0.1 1.2e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB10765.1 - 5.6e-40 137.4 1.1 7.3e-40 137.0 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB10765.1 - 1.6e-11 44.4 0.8 2.3e-11 44.0 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB10765.1 - 8.8e-05 22.1 0.4 0.00012 21.6 0.4 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGB10765.1 - 0.0056 16.6 0.2 0.0087 16.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGB10765.1 - 0.012 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 EGB10765.1 - 0.034 14.2 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TFIIB PF00382.19 EGB10765.1 - 0.61 10.2 0.0 0.61 10.2 0.0 2.3 3 0 0 3 3 3 0 Transcription factor TFIIB repeat Hydrolase_4 PF12146.8 EGB10766.1 - 8.2e-25 87.5 0.1 2.3e-24 86.0 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB10766.1 - 0.0001 22.1 0.0 0.033 13.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 EGB10766.1 - 0.0026 17.9 0.1 0.0042 17.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EGB10766.1 - 0.0053 16.4 0.1 0.0099 15.5 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGB10766.1 - 0.012 15.1 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EGB10766.1 - 0.015 15.4 0.3 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein DUF4418 PF14387.6 EGB10766.1 - 0.076 13.2 3.2 2.9 8.1 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) MASE3 PF17159.4 EGB10766.1 - 1.7 8.2 8.8 1.5 8.4 2.9 2.2 2 0 0 2 2 2 0 Membrane-associated sensor domain dCMP_cyt_deam_1 PF00383.23 EGB10767.1 - 7.6e-20 70.7 3.8 9.9e-20 70.3 3.8 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGB10767.1 - 1.3e-16 60.6 0.1 1.6e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EGB10767.1 - 0.018 15.2 0.2 0.027 14.6 0.2 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EGB10767.1 - 0.025 14.7 0.2 0.042 14.0 0.2 1.3 1 0 0 1 1 1 0 APOBEC3 NAD1 PF18778.1 EGB10767.1 - 0.037 14.1 0.2 0.054 13.6 0.2 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 EGB10767.1 - 0.053 13.6 0.1 0.073 13.1 0.1 1.1 1 0 0 1 1 1 0 APOBEC2 Ribosomal_L10 PF00466.20 EGB10767.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L10 GHMP_kinases_N PF00288.26 EGB10769.1 - 0.0045 17.2 0.2 0.0045 17.2 0.2 2.4 2 1 1 3 3 3 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 EGB10769.1 - 0.043 13.4 1.3 0.3 10.7 0.0 2.9 3 0 0 3 3 3 0 Galactokinase galactose-binding signature Ion_trans PF00520.31 EGB10770.1 - 1.2e-54 185.1 18.6 1.9e-31 109.2 5.2 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 EGB10770.1 - 0.0072 15.1 25.8 0.14 10.8 0.2 4.2 2 2 1 3 3 3 2 Polycystin cation channel Methyltransf_11 PF08241.12 EGB10771.1 - 0.01 16.5 0.0 0.049 14.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGB10771.1 - 0.011 16.4 0.0 0.03 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGB10771.1 - 0.02 14.7 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10771.1 - 0.067 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_gamma_lyase PF06838.11 EGB10771.1 - 0.19 10.2 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase LRR_6 PF13516.6 EGB10772.1 - 2.7e-13 48.8 5.2 0.013 15.5 0.1 7.4 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 EGB10772.1 - 6.2e-06 26.1 1.0 3.4 8.6 0.0 5.0 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 EGB10772.1 - 3e-05 24.3 0.0 2.8 8.5 0.0 4.9 2 2 2 5 5 5 1 Leucine Rich repeats (2 copies) Rhamno_transf PF11316.8 EGB10773.1 - 3.2e-09 36.5 0.0 6.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Putative rhamnosyl transferase Sulfotransfer_4 PF17784.1 EGB10773.1 - 5.6e-05 23.1 0.0 0.00033 20.6 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Pacifastin_I PF05375.13 EGB10773.1 - 2.2 8.1 16.5 0.037 13.8 8.7 2.0 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Ion_trans PF00520.31 EGB10774.1 - 4.1e-53 180.1 21.4 2.4e-30 105.6 11.4 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 EGB10774.1 - 2.2e-08 33.2 16.7 0.00091 18.0 5.4 3.6 3 1 0 3 3 3 3 Polycystin cation channel CS PF04969.16 EGB10774.1 - 0.0043 18.0 0.0 0.0084 17.1 0.0 1.5 1 0 0 1 1 1 1 CS domain DUF962 PF06127.11 EGB10774.1 - 0.93 9.6 4.5 6.7 6.9 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF962) PRA-PH PF01503.17 EGB10774.1 - 1.5 9.3 4.7 3 8.4 0.5 2.9 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase dCMP_cyt_deam_1 PF00383.23 EGB10775.1 - 2e-20 72.6 0.8 2.4e-20 72.3 0.8 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGB10775.1 - 3.3e-20 72.3 0.0 3.6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EGB10775.1 - 0.0047 17.0 0.0 0.0069 16.5 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 EGB10775.1 - 0.0051 16.7 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Inv-AAD PF18785.1 EGB10775.1 - 0.0072 16.2 1.6 0.025 14.4 1.6 1.8 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase NAD1 PF18778.1 EGB10775.1 - 0.035 14.2 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 EGB10775.1 - 0.16 12.0 7.6 1.1 9.3 1.0 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase HSF_DNA-bind PF00447.17 EGB10776.1 - 3.7e-17 62.7 0.0 6.8e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Trypan_PARP PF05887.11 EGB10776.1 - 0.00034 20.6 13.6 0.00034 20.6 13.6 9.6 9 2 0 9 9 9 2 Procyclic acidic repetitive protein (PARP) Cu_bind_like PF02298.17 EGB10776.1 - 0.034 14.2 0.0 0.085 12.9 0.0 1.7 1 0 0 1 1 1 0 Plastocyanin-like domain YHYH PF14240.6 EGB10776.1 - 2 8.3 7.4 0.4 10.6 1.7 2.5 1 1 1 2 2 2 0 YHYH protein Pro_isomerase PF00160.21 EGB10777.1 - 2.3e-15 57.2 0.0 3.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M23 PF01551.22 EGB10778.1 - 3.2e-15 56.1 0.2 6.4e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M23 PA PF02225.22 EGB10778.1 - 4.1e-07 29.9 1.7 4.9e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 PA domain MutS_V PF00488.21 EGB10779.1 - 4.7e-71 238.7 0.0 8.2e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGB10779.1 - 5.9e-31 108.2 0.7 1.4e-30 107.0 0.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EGB10779.1 - 1.3e-28 99.5 0.1 2.6e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 EGB10779.1 - 1.9e-07 31.3 0.0 4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGB10779.1 - 3.9e-07 30.4 0.0 9.8e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II Agenet PF05641.12 EGB10779.1 - 0.034 14.6 0.4 0.36 11.3 0.1 2.7 2 0 0 2 2 2 0 Agenet domain Tudor_3 PF18115.1 EGB10779.1 - 0.075 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain DUF664 PF04978.12 EGB10779.1 - 0.24 11.8 4.9 1.4 9.3 0.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF664) CDC45 PF02724.14 EGB10779.1 - 1.4 7.1 8.9 2.2 6.4 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin PF00085.20 EGB10780.1 - 5.3e-20 71.3 0.0 6.5e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB10780.1 - 2.6e-08 34.3 0.0 1.8e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EGB10780.1 - 0.00016 21.5 0.0 0.00034 20.5 0.0 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EGB10780.1 - 0.0018 18.4 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EGB10780.1 - 0.0019 18.5 0.0 0.11 12.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EGB10780.1 - 0.0025 17.6 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 EGB10780.1 - 0.0091 16.4 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EGB10780.1 - 0.077 13.2 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 Glutaredoxin C2 PF00168.30 EGB10781.1 - 3e-10 40.3 0.0 6.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain IQ PF00612.27 EGB10781.1 - 8.1 6.5 13.1 22 5.2 1.2 4.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif AAA PF00004.29 EGB10782.1 - 7.4e-14 52.3 0.0 1.3e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGB10782.1 - 2.3e-13 50.2 0.0 2.6e-10 40.3 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EGB10782.1 - 3.4e-12 46.6 0.0 6.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 EGB10782.1 - 2e-08 34.4 0.0 3.5e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EGB10782.1 - 0.00012 21.9 1.3 0.0004 20.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 EGB10782.1 - 0.00014 21.6 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 EGB10782.1 - 0.00024 21.4 0.0 0.00065 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 EGB10782.1 - 0.00043 20.1 0.0 0.00087 19.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EGB10782.1 - 0.00095 19.0 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EGB10782.1 - 0.0012 19.3 0.0 0.0057 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EGB10782.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB10782.1 - 0.0018 18.6 0.5 0.13 12.6 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 EGB10782.1 - 0.0019 18.5 1.0 1.6 9.0 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 EGB10782.1 - 0.0037 17.3 0.3 0.15 12.1 0.2 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGB10782.1 - 0.0042 17.1 0.0 0.014 15.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 EGB10782.1 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 EGB10782.1 - 0.01 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) MCM PF00493.23 EGB10782.1 - 0.11 11.6 0.0 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain SNF2_N PF00176.23 EGB10782.1 - 0.17 10.6 0.0 0.34 9.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ank_2 PF12796.7 EGB10783.1 - 6.1e-41 138.9 0.2 2.1e-15 57.1 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB10783.1 - 8.4e-29 96.4 0.2 0.0023 18.3 0.0 6.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EGB10783.1 - 6.8e-26 90.3 1.1 8.8e-09 35.7 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB10783.1 - 1.1e-23 83.0 6.8 1.4e-05 25.3 0.0 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EGB10783.1 - 8.7e-20 70.2 1.0 0.046 14.2 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Sel1 PF08238.12 EGB10784.1 - 3.4e-21 75.2 8.3 2.8e-09 37.3 0.1 3.4 3 1 0 3 3 3 3 Sel1 repeat MIT PF04212.18 EGB10784.1 - 0.017 15.2 1.2 0.095 12.8 0.6 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EGB10784.1 - 0.059 13.7 3.1 0.3 11.4 2.0 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF4297 PF14130.6 EGB10784.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) TPR_2 PF07719.17 EGB10784.1 - 9 6.7 9.9 4 7.8 1.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 EGB10785.1 - 8e-36 123.7 0.0 8.7e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lipoprotein_X PF03305.13 EGB10785.1 - 0.044 13.6 0.6 0.075 12.8 0.3 1.4 1 1 0 1 1 1 0 Mycoplasma MG185/MG260 protein eRF1_1 PF03463.15 EGB10786.1 - 9.8e-28 96.7 0.1 1.1e-27 96.6 0.1 1.0 1 0 0 1 1 1 1 eRF1 domain 1 Methyltransf_16 PF10294.9 EGB10787.1 - 2.4e-12 46.9 0.0 3.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGB10787.1 - 3.8e-08 33.0 0.0 7.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB10787.1 - 6.4e-08 33.2 1.3 2e-07 31.6 0.3 2.4 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 EGB10787.1 - 1.4e-06 27.9 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGB10787.1 - 1.7e-06 27.9 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10787.1 - 0.00085 20.0 0.1 0.0029 18.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB10787.1 - 0.0012 19.4 0.4 0.0063 17.1 0.2 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB10787.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB10787.1 - 0.099 12.3 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TehB PF03848.14 EGB10787.1 - 0.24 10.8 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Dimer_Tnp_hAT PF05699.14 EGB10789.1 - 0.00039 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DNA_pol3_a_NI PF14480.6 EGB10789.1 - 0.038 14.0 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I VWA_CoxE PF05762.14 EGB10790.1 - 0.012 15.0 0.1 0.081 12.3 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EGB10790.1 - 0.018 15.7 0.0 6 7.6 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain FKBP_C PF00254.28 EGB10792.1 - 2.8e-22 78.8 0.0 3.6e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 EGB10792.1 - 9.4e-07 29.7 0.0 3e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Lig_chan PF00060.26 EGB10793.1 - 0.0021 17.9 1.4 0.0061 16.4 1.4 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel Ion_trans_2 PF07885.16 EGB10793.1 - 0.0072 16.3 1.2 0.015 15.3 1.2 1.5 1 0 0 1 1 1 1 Ion channel DUF938 PF06080.12 EGB10794.1 - 3.9e-38 131.3 0.0 4.6e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 EGB10794.1 - 4.6e-09 36.9 0.0 7.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB10794.1 - 6.9e-05 22.5 0.0 0.00062 19.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGB10794.1 - 0.00077 20.1 0.0 0.0014 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10794.1 - 0.0014 19.3 0.0 0.0021 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB10794.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGB10794.1 - 0.16 11.8 0.0 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain PepSY_2 PF13670.6 EGB10794.1 - 2.8 8.0 4.7 9.8 6.3 0.4 2.8 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain Sec61_beta PF03911.16 EGB10795.1 - 2e-18 66.2 0.2 2.3e-18 65.9 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Pkinase_Tyr PF07714.17 EGB10796.1 - 9.7e-35 120.1 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB10796.1 - 3.8e-32 111.7 0.0 5.2e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain XRN_N PF03159.18 EGB10796.1 - 2.9e-20 72.7 0.0 4.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Rhomboid PF01694.22 EGB10796.1 - 0.00016 21.7 0.1 0.00016 21.7 0.1 2.2 3 0 0 3 3 3 1 Rhomboid family Cul7 PF11515.8 EGB10796.1 - 0.036 14.4 1.6 3.2 8.1 0.0 3.4 4 0 0 4 4 4 0 Mouse development and cellular proliferation protein Cullin-7 Sulfotransfer_4 PF17784.1 EGB10798.1 - 1.8e-48 165.2 0.0 2.1e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB10798.1 - 0.59 10.5 3.3 7.3 6.9 0.1 2.5 2 1 0 3 3 3 0 Sulfotransferase family Sulfatase PF00884.23 EGB10799.1 - 6.2e-49 167.1 0.0 7.5e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 EGB10799.1 - 0.064 14.0 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 EGB10799.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Lipase_3 PF01764.25 EGB10800.1 - 7.1e-07 29.2 0.0 9.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) FAD_binding_7 PF03441.14 EGB10801.1 - 1.4e-48 165.1 0.0 2.1e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGB10801.1 - 4.1e-30 105.0 0.0 6.3e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase MORN PF02493.20 EGB10802.1 - 3.3e-15 55.0 17.6 1.3e-05 24.8 1.1 4.9 5 0 0 5 5 5 3 MORN repeat RNA_pol_Rpc34 PF05158.12 EGB10803.1 - 4.2e-61 207.2 3.4 5.7e-53 180.5 1.9 2.3 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit DUF2603 PF10788.9 EGB10803.1 - 0.0008 19.5 1.2 0.0052 16.8 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2603) RPA_C PF08784.11 EGB10803.1 - 0.0014 19.2 0.7 0.026 15.2 0.2 2.7 3 0 0 3 3 3 1 Replication protein A C terminal B-block_TFIIIC PF04182.12 EGB10803.1 - 0.0018 18.4 0.4 0.0036 17.4 0.4 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 EGB10803.1 - 0.009 15.9 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 MarR family Lipoxygenase PF00305.19 EGB10803.1 - 0.0093 14.4 0.1 0.011 14.2 0.1 1.1 1 0 0 1 1 1 1 Lipoxygenase Rio2_N PF09202.11 EGB10803.1 - 0.016 15.4 0.3 0.034 14.4 0.3 1.6 1 0 0 1 1 1 0 Rio2, N-terminal Sigma54_activ_2 PF14532.6 EGB10803.1 - 0.017 15.2 2.4 0.033 14.3 0.9 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF5101 PF17031.5 EGB10803.1 - 0.02 15.0 0.3 0.32 11.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) HTH_20 PF12840.7 EGB10803.1 - 0.031 14.3 0.1 0.081 13.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 EGB10803.1 - 0.054 14.0 1.8 0.092 13.3 0.4 2.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain TrmB PF01978.19 EGB10803.1 - 0.084 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 EGB10803.1 - 0.086 12.8 0.5 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family GlnD_UR_UTase PF08335.11 EGB10803.1 - 0.12 12.5 1.8 0.2 11.7 1.8 1.4 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase MarR PF01047.22 EGB10803.1 - 0.15 12.0 0.4 0.3 11.0 0.4 1.5 1 0 0 1 1 1 0 MarR family TFIIE_alpha PF02002.17 EGB10803.1 - 0.15 11.9 3.5 0.095 12.6 1.1 1.9 2 1 0 2 2 2 0 TFIIE alpha subunit Ets PF00178.22 EGB10803.1 - 0.25 11.8 1.0 0.58 10.7 1.0 1.6 1 0 0 1 1 1 0 Ets-domain DNA_methylase PF00145.17 EGB10805.1 - 2.3e-09 37.1 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase HNH_3 PF13392.6 EGB10805.1 - 3.2e-06 26.8 0.4 9e-06 25.4 0.4 1.9 1 0 0 1 1 1 1 HNH endonuclease IQ PF00612.27 EGB10805.1 - 0.55 10.2 1.8 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif Synaptobrevin PF00957.21 EGB10806.1 - 1.7e-21 75.8 2.7 1.9e-21 75.7 2.7 1.0 1 0 0 1 1 1 1 Synaptobrevin Methyltransf_2 PF00891.18 EGB10807.1 - 0.00024 20.5 0.1 0.00037 19.8 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Chloroa_b-bind PF00504.21 EGB10808.1 - 2.7e-34 119.0 0.0 3.4e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein AAA_12 PF13087.6 EGB10809.1 - 1.7e-25 89.8 0.0 2.4e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 EGB10809.1 - 0.0008 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD_C_2 PF13538.6 EGB10809.1 - 0.0016 18.2 0.0 0.0073 16.1 0.0 2.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Glyco_hydro_20 PF00728.22 EGB10810.1 - 9.8e-63 212.7 0.0 2.8e-62 211.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGB10810.1 - 1.7e-15 57.9 0.0 1.8e-14 54.5 0.0 2.2 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGB10810.1 - 9.2e-05 23.2 0.0 0.00024 21.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Gly_rich_SFCGS PF14272.6 EGB10810.1 - 0.015 15.3 2.0 3.6 7.6 0.2 2.4 2 0 0 2 2 2 0 Glycine-rich SFCGS 3HCDH_RFF PF18321.1 EGB10810.1 - 0.19 12.2 1.8 0.35 11.3 0.1 2.4 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain ThiF PF00899.21 EGB10811.1 - 1.8e-35 122.4 0.3 2.2e-35 122.2 0.3 1.0 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 EGB10811.1 - 0.0011 18.5 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EGB10811.1 - 0.0037 17.7 2.4 0.023 15.1 2.4 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.16 EGB10811.1 - 0.028 14.1 0.3 0.035 13.8 0.3 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 EGB10811.1 - 0.033 14.3 0.6 0.061 13.4 0.1 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGB10811.1 - 0.035 14.4 4.0 0.32 11.3 4.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EGB10811.1 - 0.056 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CagA PF03507.13 EGB10811.1 - 0.069 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 CagA exotoxin TrkA_N PF02254.18 EGB10811.1 - 0.14 12.4 0.4 3.3 8.0 0.0 2.1 1 1 1 2 2 2 0 TrkA-N domain acVLRF1 PF18859.1 EGB10811.1 - 0.63 10.3 3.8 1.7 9.0 0.7 2.3 1 1 1 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Glyco_hydro_20 PF00728.22 EGB10812.1 - 9.3e-41 140.4 0.0 3e-40 138.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain 3HCDH_RFF PF18321.1 EGB10812.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.1 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain ThiF PF00899.21 EGB10813.1 - 3.3e-35 121.6 0.1 3.9e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 EGB10813.1 - 0.0021 17.7 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EGB10813.1 - 0.0053 17.2 1.4 0.03 14.8 1.4 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.16 EGB10813.1 - 0.04 13.6 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 EGB10813.1 - 0.062 13.4 0.6 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGB10813.1 - 0.068 12.5 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGB10813.1 - 0.087 13.1 3.9 0.73 10.1 3.9 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CagA PF03507.13 EGB10813.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.2 1 0 0 1 1 1 0 CagA exotoxin Nuc_sug_transp PF04142.15 EGB10814.1 - 1.4e-83 280.7 10.1 1.6e-83 280.4 10.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGB10814.1 - 5.7 6.0 9.6 3.1 6.9 5.8 2.3 1 1 0 2 2 2 0 UAA transporter family GRIP PF01465.20 EGB10815.1 - 2.2e-08 33.8 0.0 3.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 GRIP domain HALZ PF02183.18 EGB10815.1 - 0.9 9.8 5.1 33 4.8 0.1 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper TMEM189_B_dmain PF10520.9 EGB10817.1 - 4e-18 66.1 0.9 6.8e-18 65.4 0.9 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain Cytochrom_B561 PF03188.16 EGB10817.1 - 6.9e-07 29.5 1.0 1.1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 FA_hydroxylase PF04116.13 EGB10817.1 - 0.00077 19.8 3.3 0.0017 18.7 3.3 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily TauD PF02668.16 EGB10818.1 - 1.3e-56 192.4 0.2 1.5e-56 192.2 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MIF4G PF02854.19 EGB10819.1 - 2.3e-37 128.7 1.0 3.4e-37 128.1 1.0 1.2 1 0 0 1 1 1 1 MIF4G domain Mito_carr PF00153.27 EGB10820.1 - 2e-57 191.1 4.8 1.1e-19 70.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4884 PF16225.5 EGB10820.1 - 0.16 12.1 0.8 0.35 11.0 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) Kinesin PF00225.23 EGB10821.1 - 2.5e-90 302.8 0.0 2.8e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB10821.1 - 7.9e-16 58.3 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Patched PF02460.18 EGB10822.1 - 3.1e-16 58.7 12.2 1.6e-11 43.1 0.5 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EGB10822.1 - 5.6e-14 52.2 4.2 5.6e-14 52.2 4.2 2.8 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EGB10822.1 - 6.4e-14 51.6 34.0 1e-11 44.4 6.1 2.5 2 0 0 2 2 2 2 MMPL family Methyltransf_11 PF08241.12 EGB10822.1 - 7.4e-08 32.9 0.1 1.7e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB10822.1 - 1.3e-05 25.8 0.1 3.6e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain EGF_2 PF07974.13 EGB10822.1 - 0.00039 20.7 7.1 0.00091 19.5 7.1 1.7 1 0 0 1 1 1 1 EGF-like domain Ribosomal_L2 PF00181.23 EGB10822.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain Methyltransf_12 PF08242.12 EGB10822.1 - 0.069 13.9 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2628 PF10947.8 EGB10822.1 - 4.7 7.6 8.3 0.1 13.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) EF-hand_6 PF13405.6 EGB10823.1 - 2.1e-36 120.7 20.3 0.00014 21.5 0.0 9.6 9 0 0 9 9 9 8 EF-hand domain EF-hand_1 PF00036.32 EGB10823.1 - 1.7e-34 114.7 26.1 0.0018 17.7 0.5 9.5 9 0 0 9 9 9 9 EF hand EF-hand_7 PF13499.6 EGB10823.1 - 1.5e-32 111.8 24.2 1.4e-07 31.8 0.3 5.5 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_8 PF13833.6 EGB10823.1 - 8.5e-24 83.2 21.5 6.6e-08 32.3 0.7 6.4 5 1 1 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB10823.1 - 1e-22 78.6 35.3 0.011 15.2 0.4 9.6 9 0 0 9 9 9 7 EF hand SPARC_Ca_bdg PF10591.9 EGB10823.1 - 1.3e-05 25.4 0.4 3.2 8.1 0.0 4.3 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region TPR_12 PF13424.6 EGB10823.1 - 0.00068 19.9 0.4 0.42 10.9 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat EF-hand_10 PF14788.6 EGB10823.1 - 0.0025 17.6 0.5 14 5.6 0.0 4.7 5 0 0 5 5 5 1 EF hand TPR_2 PF07719.17 EGB10823.1 - 0.032 14.3 0.0 13 6.2 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat YolD PF08863.10 EGB10823.1 - 0.26 11.3 2.0 49 4.1 0.0 3.9 4 0 0 4 4 4 0 YolD-like protein Ssl1 PF04056.14 EGB10824.1 - 5.2e-41 140.6 0.0 6.7e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 EGB10824.1 - 1.8e-07 31.8 0.0 2.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 EGB10824.1 - 1.9e-06 28.0 8.5 1.9e-06 28.0 8.5 2.2 2 0 0 2 2 2 1 TFIIH C1-like domain DUF1610 PF07754.11 EGB10824.1 - 0.00073 19.4 16.5 0.078 13.0 6.7 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1610) DZR PF12773.7 EGB10824.1 - 0.0016 18.5 15.6 0.038 14.0 6.1 2.5 1 1 1 2 2 2 2 Double zinc ribbon IBR PF01485.21 EGB10824.1 - 0.048 13.9 6.2 0.14 12.4 6.2 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 EGB10824.1 - 0.88 9.5 13.3 8.8 6.3 0.8 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 EGB10824.1 - 2 8.6 9.7 0.38 10.9 2.6 2.4 2 0 0 2 2 2 0 B-box zinc finger EF-hand_7 PF13499.6 EGB10825.1 - 8.8e-37 125.4 12.2 1.3e-12 47.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EGB10825.1 - 1.2e-34 115.2 23.0 7.5e-06 25.1 0.1 7.2 8 0 0 8 8 8 6 EF hand EF-hand_6 PF13405.6 EGB10825.1 - 3e-33 110.9 17.8 1.2e-05 24.8 0.1 7.4 8 0 0 8 8 8 6 EF-hand domain EF-hand_5 PF13202.6 EGB10825.1 - 9e-25 85.0 19.6 0.0002 20.7 0.0 7.2 7 0 0 7 7 7 6 EF hand EF-hand_8 PF13833.6 EGB10825.1 - 2e-22 78.8 18.5 1.7e-09 37.4 0.0 6.8 5 3 2 8 8 8 4 EF-hand domain pair EF-hand_11 PF08976.11 EGB10825.1 - 6.2e-05 23.8 0.5 0.09 13.7 0.1 4.0 4 1 0 4 4 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB10825.1 - 0.00013 22.2 0.0 0.13 12.6 0.1 3.7 4 1 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGB10825.1 - 0.0018 18.2 0.9 15 5.6 0.0 4.0 2 2 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand FGAR-AT_linker PF18072.1 EGB10825.1 - 0.0022 18.5 0.0 11 6.7 0.0 3.7 4 0 0 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_14 PF17959.1 EGB10825.1 - 0.0031 17.8 1.1 1.8 8.9 0.2 3.9 3 1 0 3 3 3 1 EF-hand domain DUF5580 PF17743.1 EGB10825.1 - 0.0035 15.9 0.0 0.59 8.6 0.0 2.4 3 0 0 3 3 3 2 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 EGB10825.1 - 0.0042 17.3 5.1 2.4 8.4 0.1 4.0 3 2 1 4 4 3 2 Dockerin type I domain EF-hand_10 PF14788.6 EGB10825.1 - 0.0099 15.7 5.1 1.9 8.4 0.2 4.6 5 1 1 6 6 6 1 EF hand SurA_N_3 PF13624.6 EGB10825.1 - 0.012 15.4 0.0 0.47 10.2 0.0 2.8 3 0 0 3 3 3 0 SurA N-terminal domain Caleosin PF05042.13 EGB10825.1 - 0.016 15.2 0.0 13 5.6 0.0 3.6 3 1 0 3 3 3 0 Caleosin related protein EF-hand_9 PF14658.6 EGB10825.1 - 0.074 13.4 0.3 10 6.5 0.0 3.9 5 1 0 5 5 4 0 EF-hand domain SurA_N_2 PF13623.6 EGB10825.1 - 0.12 12.3 0.0 36 4.2 0.0 3.5 3 1 0 3 3 3 0 SurA N-terminal domain FtsH_ext PF06480.15 EGB10825.1 - 0.16 12.3 0.0 1.1e+02 3.2 0.0 3.2 3 0 0 3 3 3 0 FtsH Extracellular KRTAP PF11759.8 EGB10826.1 - 0.21 12.2 52.0 2 9.0 15.6 3.0 1 1 1 2 2 2 0 Keratin-associated matrix Metallophos PF00149.28 EGB10827.1 - 2.5e-21 77.1 0.1 3e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_lid_8 PF17868.1 EGB10827.1 - 0.02 14.8 0.0 0.71 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA lid domain C2 PF00168.30 EGB10828.1 - 1.6e-15 57.3 0.0 2.8e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 EGB10828.1 - 0.074 12.5 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain EF-hand_1 PF00036.32 EGB10829.1 - 1.6e-08 33.5 0.0 0.0045 16.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB10829.1 - 2.5e-08 33.0 0.0 0.0025 17.2 0.0 2.8 2 0 0 2 2 2 2 EF hand C2 PF00168.30 EGB10829.1 - 4.5e-07 30.1 0.0 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 EGB10829.1 - 5.2e-06 26.0 0.0 0.15 12.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB10829.1 - 1.5e-05 25.3 0.0 3.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair PH PF00169.29 EGB10829.1 - 0.00013 22.4 0.0 0.0003 21.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PRT_C PF08372.10 EGB10829.1 - 0.0004 20.2 0.1 0.0027 17.5 0.1 2.2 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal PC-Esterase PF13839.6 EGB10829.1 - 0.01 15.6 0.0 0.034 13.9 0.0 1.9 1 1 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PH_6 PF15406.6 EGB10829.1 - 0.36 11.1 1.2 10 6.4 0.9 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain DEAD PF00270.29 EGB10830.1 - 1.2e-39 135.9 0.0 2.7e-39 134.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB10830.1 - 1.4e-28 99.4 0.0 3.4e-28 98.2 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 EGB10830.1 - 0.0026 17.8 1.6 0.0026 17.8 1.6 1.9 2 0 0 2 2 2 1 Zinc knuckle ResIII PF04851.15 EGB10830.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ArabFuran-catal PF09206.11 EGB10831.1 - 1.2e-125 419.0 6.3 1.4e-125 418.8 6.3 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic Amidohydro_1 PF01979.20 EGB10832.1 - 7.6e-11 41.9 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EGB10832.1 - 0.032 14.0 0.1 0.052 13.3 0.1 1.5 1 1 0 1 1 1 0 Amidohydrolase RNA_pol_A_bac PF01000.26 EGB10833.1 - 1.4e-27 96.2 0.0 2.6e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGB10833.1 - 1.1e-13 50.4 0.0 1.8e-13 49.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cyt-b5 PF00173.28 EGB10834.1 - 4.9e-11 42.6 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_8 PF13450.6 EGB10834.1 - 2.1e-10 40.7 0.0 2.1e-10 40.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGB10834.1 - 1.4e-08 34.5 0.4 0.004 16.5 0.1 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 EGB10834.1 - 7.5e-08 32.3 2.0 1.9e-07 31.0 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EGB10834.1 - 1.9e-06 27.3 0.1 3.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EGB10834.1 - 2.3e-06 27.1 0.8 0.0002 20.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGB10834.1 - 4e-05 23.0 0.0 7.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EGB10834.1 - 0.00019 20.7 0.1 0.00019 20.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EGB10834.1 - 0.0021 17.3 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EGB10834.1 - 0.0022 18.0 0.3 1.1 9.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EGB10834.1 - 0.0039 17.1 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EGB10834.1 - 0.0044 16.4 0.0 0.0044 16.4 0.0 2.5 3 0 0 3 3 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGB10834.1 - 0.024 13.7 0.4 0.024 13.7 0.4 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 EGB10834.1 - 0.043 13.1 0.2 0.11 11.8 0.2 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EGB10834.1 - 0.046 14.3 0.7 0.13 12.8 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGB10834.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EGB10834.1 - 0.084 11.6 0.6 0.35 9.5 0.3 1.9 2 0 0 2 2 2 0 HI0933-like protein TPR_8 PF13181.6 EGB10836.1 - 0.0081 16.3 0.1 6.2 7.3 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB10836.1 - 0.043 14.3 1.6 0.043 14.3 1.6 3.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB10836.1 - 0.046 14.1 0.5 0.76 10.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10836.1 - 0.068 13.3 7.7 5 7.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PHD PF00628.29 EGB10837.1 - 0.007 16.2 7.0 0.007 16.2 7.0 3.2 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.6 EGB10837.1 - 0.0095 16.2 5.5 0.0095 16.2 5.5 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain LrgB PF04172.16 EGB10838.1 - 6.3e-36 123.9 18.0 6.3e-36 123.9 18.0 2.2 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 EGB10838.1 - 0.00042 20.2 2.4 0.00042 20.2 2.4 2.9 4 0 0 4 4 4 1 LrgA family Kinesin PF00225.23 EGB10839.1 - 7.8e-89 297.9 0.0 9e-89 297.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB10839.1 - 4.4e-37 127.3 0.0 1.3e-36 125.8 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 EGB10839.1 - 0.069 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGB10839.1 - 0.14 12.4 0.5 0.65 10.3 0.2 2.1 2 0 0 2 2 2 0 AAA domain WGG PF10273.9 EGB10840.1 - 2.2e-17 63.5 0.1 3.2e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 UPF1_Zn_bind PF09416.10 EGB10841.1 - 9.6e-64 214.0 0.3 3.1e-63 212.3 0.3 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EGB10841.1 - 6.8e-55 185.8 0.0 1e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGB10841.1 - 1.4e-46 159.4 2.1 2.1e-26 93.3 0.2 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EGB10841.1 - 2e-22 79.2 0.0 3.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EGB10841.1 - 8.8e-16 58.2 1.9 5.2e-15 55.7 1.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB10841.1 - 7.1e-12 45.9 0.5 2.2e-11 44.3 0.5 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGB10841.1 - 2.5e-06 27.6 0.0 4.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EGB10841.1 - 9.6e-05 22.0 0.3 0.013 15.1 0.2 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EGB10841.1 - 0.00012 22.0 0.1 0.00021 21.2 0.1 1.5 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EGB10841.1 - 0.00023 21.0 0.5 0.18 11.5 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGB10841.1 - 0.0015 17.9 0.0 0.12 11.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EGB10841.1 - 0.0034 16.7 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 KaiC PIF1 PF05970.14 EGB10841.1 - 0.0077 15.4 0.2 3.1 6.8 0.1 2.2 2 0 0 2 2 2 2 PIF1-like helicase PhoH PF02562.16 EGB10841.1 - 0.011 15.2 0.1 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 EGB10841.1 - 0.048 14.1 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB10841.1 - 0.05 14.0 1.6 0.071 13.5 0.2 1.9 2 1 0 2 2 1 0 AAA ATPase domain SRP54 PF00448.22 EGB10841.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.29 EGB10841.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Kinesin PF00225.23 EGB10842.1 - 1.1e-37 129.7 0.0 1.3e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Ank_4 PF13637.6 EGB10843.1 - 1.4e-17 63.8 1.4 1.1e-06 29.1 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB10843.1 - 2e-13 50.3 1.2 7.3e-07 29.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB10843.1 - 3.6e-13 49.9 0.1 4.6e-12 46.4 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGB10843.1 - 6.2e-11 42.2 0.3 3.3e-05 24.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB10843.1 - 3.8e-10 39.1 0.0 0.0014 18.9 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat AnkUBD PF18418.1 EGB10843.1 - 0.0094 16.1 0.2 4.3 7.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin ubiquitin-binding domain ACBP PF00887.19 EGB10844.1 - 6e-17 61.6 0.0 6.3e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein adh_short_C2 PF13561.6 EGB10845.1 - 9.5e-37 126.8 0.3 1.2e-36 126.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB10845.1 - 1.4e-27 96.4 0.1 2.4e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB10845.1 - 1.4e-06 28.4 0.6 2.1e-06 27.8 0.6 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EGB10845.1 - 0.032 13.5 0.3 0.072 12.4 0.2 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 EGB10845.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 EGB10845.1 - 0.24 11.3 1.0 0.36 10.7 1.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Arm PF00514.23 EGB10846.1 - 5.3e-52 172.4 25.8 1.8e-08 34.1 0.1 8.3 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat PRORP PF16953.5 EGB10846.1 - 2.1e-13 50.4 0.0 3.1e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Protein-only RNase P HEAT PF02985.22 EGB10846.1 - 2.7e-12 45.8 15.0 0.074 13.4 0.1 8.1 7 0 0 7 7 7 4 HEAT repeat Atx10homo_assoc PF09759.9 EGB10846.1 - 5.5e-12 45.6 0.9 0.00098 19.1 0.0 4.5 3 1 0 4 4 4 3 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 EGB10846.1 - 2.1e-10 40.9 55.4 8.6e-05 22.9 5.8 5.6 3 1 3 6 6 6 4 HEAT repeats Arm_2 PF04826.13 EGB10846.1 - 9.3e-10 38.4 0.1 0.027 13.9 0.0 4.0 1 1 2 4 4 4 3 Armadillo-like Cnd1 PF12717.7 EGB10846.1 - 4.4e-08 33.3 0.0 0.14 12.2 0.0 3.8 2 1 2 4 4 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGB10846.1 - 2.6e-07 31.0 40.3 0.00036 21.0 0.7 8.5 4 2 4 8 8 7 5 HEAT-like repeat Adaptin_N PF01602.20 EGB10846.1 - 0.022 13.3 0.0 2.5 6.6 0.0 2.5 1 1 0 2 2 2 0 Adaptin N terminal region RICTOR_N PF14664.6 EGB10846.1 - 0.15 11.0 0.2 1.1e+02 1.6 0.0 3.9 1 1 3 5 5 5 0 Rapamycin-insensitive companion of mTOR, N-term Aconitase_B_N PF11791.8 EGB10846.1 - 0.36 10.9 5.0 16 5.5 0.1 4.5 1 1 2 5 5 5 0 Aconitate B N-terminal domain SKG6 PF08693.10 EGB10846.1 - 9.3 5.8 14.3 14 5.1 0.4 5.5 6 0 0 6 6 6 0 Transmembrane alpha-helix domain EF-hand_7 PF13499.6 EGB10848.1 - 3.4e-10 40.2 5.1 0.00014 22.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB10848.1 - 5.4e-08 32.2 1.9 0.00032 20.4 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGB10848.1 - 2.9e-07 29.5 4.5 0.00053 19.3 0.0 3.8 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGB10848.1 - 0.0022 17.8 1.2 0.86 9.5 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 EGB10848.1 - 0.0048 17.2 0.3 0.36 11.2 0.1 2.4 2 1 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 EGB10848.1 - 0.025 14.7 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Arena_nucleocap PF00843.17 EGB10848.1 - 0.037 12.9 0.6 0.042 12.7 0.6 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain CopG_antitoxin PF12441.8 EGB10848.1 - 0.12 12.9 0.1 0.26 11.9 0.1 1.6 1 1 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system FAA_hydrolase PF01557.18 EGB10849.1 - 1.8e-26 93.2 0.0 4.1e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PTPS PF01242.19 EGB10850.1 - 3.7e-21 75.3 0.0 4.8e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase CENP-T_C PF15511.6 EGB10851.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB10851.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB10851.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB10851.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB10851.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB10851.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB10851.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGB10851.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EGB10852.1 - 3.9e-16 59.6 0.5 4.8e-16 59.3 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB10852.1 - 0.0038 17.5 0.1 0.0098 16.2 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB10852.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A MIP PF00230.20 EGB10853.1 - 1.5e-13 51.0 11.3 4.8e-13 49.3 11.3 1.8 1 1 0 1 1 1 1 Major intrinsic protein DUF3488 PF11992.8 EGB10853.1 - 1.5 7.7 4.4 0.56 9.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) DUF202 PF02656.15 EGB10853.1 - 2.1 8.9 6.5 6.2 7.4 2.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Histidinol_dh PF00815.20 EGB10854.1 - 4.2e-116 388.3 7.6 5e-116 388.1 7.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase RNA_pol_Rpb6 PF01192.22 EGB10855.1 - 2.2e-15 56.3 0.2 2.6e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 CIAPIN1 PF05093.13 EGB10856.1 - 3.8e-10 40.2 13.0 5.2e-09 36.5 3.9 2.4 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Glyco_hydro_28 PF00295.17 EGB10856.1 - 0.052 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 HSF_DNA-bind PF00447.17 EGB10857.1 - 9.1e-12 45.4 0.0 3.5e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 HSF-type DNA-binding zf-RanBP PF00641.18 EGB10857.1 - 0.00075 18.8 1.9 0.0016 17.7 1.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others FKBP_C PF00254.28 EGB10859.1 - 2e-17 63.3 0.0 2.2e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PseudoU_synth_1 PF01416.20 EGB10860.1 - 3.2e-21 75.8 0.0 1.6e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase PseudoU_synth_1 PF01416.20 EGB10861.1 - 2.5e-19 69.7 0.0 5.5e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Herpes_UL25 PF01499.16 EGB10862.1 - 1.1 7.8 2.3 1.4 7.4 2.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family BUD22 PF09073.10 EGB10862.1 - 8.6 5.6 17.8 11 5.3 17.8 1.3 1 0 0 1 1 1 0 BUD22 Rubredoxin PF00301.20 EGB10863.1 - 2.6e-11 43.4 5.6 3.8e-11 42.8 5.6 1.3 1 0 0 1 1 1 1 Rubredoxin DUF3715 PF12509.8 EGB10863.1 - 0.097 12.7 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Mito_carr PF00153.27 EGB10864.1 - 2.6e-35 120.2 2.3 1.1e-11 44.5 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 EGB10865.1 - 3.1e-45 152.0 4.0 2.8e-19 68.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 EGB10866.1 - 6.1e-11 42.7 11.0 0.00098 19.9 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB10866.1 - 0.001 19.3 0.0 0.17 12.2 0.0 3.5 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGB10866.1 - 0.0069 16.8 0.1 10 6.8 0.2 4.5 4 1 0 4 4 4 1 PQQ-like domain LRR_6 PF13516.6 EGB10867.1 - 6.9e-14 50.6 9.4 0.018 15.1 0.2 7.1 7 0 0 7 7 7 5 Leucine Rich repeat TPR_2 PF07719.17 EGB10868.1 - 2.3e-08 33.5 8.7 0.00016 21.5 1.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB10868.1 - 2.5e-05 23.9 5.8 7.9e-05 22.3 1.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10868.1 - 0.0002 21.3 2.4 0.015 15.4 0.5 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGB10868.1 - 0.00046 20.3 1.2 0.0022 18.1 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB10868.1 - 0.00048 20.7 8.6 0.0036 17.9 3.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB10868.1 - 0.0013 18.9 0.7 0.011 16.1 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB10868.1 - 0.0015 18.2 4.6 0.26 11.0 0.3 3.2 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 EGB10868.1 - 0.016 16.0 6.3 1.9 9.5 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB10868.1 - 0.018 15.1 0.6 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10868.1 - 0.021 15.1 4.6 0.13 12.5 0.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB10868.1 - 0.035 14.6 3.8 0.66 10.5 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 EGB10868.1 - 0.048 14.1 3.4 4 7.9 0.2 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 EGB10868.1 - 0.058 13.6 0.2 0.15 12.3 0.1 1.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGB10868.1 - 1.2 10.0 4.1 50 4.8 0.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGB10868.1 - 2.6 8.9 11.3 13 6.7 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 EGB10869.1 - 4.2e-20 71.7 0.0 5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glycolytic PF00274.19 EGB10870.1 - 5.6e-112 373.9 0.0 6.8e-112 373.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I PK PF00224.21 EGB10870.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Pkinase PF00069.25 EGB10871.1 - 1.7e-33 116.1 0.0 1.9e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10871.1 - 5.3e-27 94.7 0.0 6.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB10871.1 - 7e-05 22.3 0.0 9.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB10871.1 - 0.00038 20.5 1.2 0.0006 19.8 1.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB10871.1 - 0.0026 16.6 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB10871.1 - 0.15 11.4 0.1 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AOX PF01786.17 EGB10872.1 - 4.9e-27 94.9 0.0 5.9e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Alternative oxidase LSM PF01423.22 EGB10873.1 - 7.9e-18 63.9 0.7 1e-17 63.6 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGB10873.1 - 0.0005 20.2 0.2 0.00064 19.8 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.8 EGB10873.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) BPL_C PF02237.17 EGB10873.1 - 0.061 13.2 0.8 0.11 12.4 0.8 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Hfq PF17209.3 EGB10873.1 - 0.15 11.8 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Hfq protein PhoLip_ATPase_C PF16212.5 EGB10874.1 - 3.1e-39 135.2 0.9 3.1e-39 135.2 0.9 1.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGB10874.1 - 3e-10 40.8 0.2 9.1e-05 22.8 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGB10874.1 - 1.5e-07 31.4 0.0 4.5e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGB10874.1 - 0.003 17.3 0.1 0.007 16.1 0.2 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGB10874.1 - 0.024 15.0 0.0 8.6 6.7 0.0 2.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase cobW PF02492.19 EGB10876.1 - 3.7e-27 95.1 0.0 4.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGB10876.1 - 0.0016 18.6 0.1 0.003 17.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB10876.1 - 0.0037 17.5 0.0 0.0057 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGB10876.1 - 0.018 14.9 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase MobB PF03205.14 EGB10876.1 - 0.027 14.4 0.1 0.19 11.6 0.1 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 EGB10876.1 - 0.046 13.8 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EGB10876.1 - 0.085 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TsaE PF02367.17 EGB10876.1 - 0.14 12.2 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EGB10876.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EGB10876.1 - 0.19 10.7 0.2 0.29 10.1 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGB10876.1 - 0.22 12.1 0.1 0.4 11.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGB10876.1 - 0.23 11.2 0.0 0.28 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase 2OG-FeII_Oxy_3 PF13640.6 EGB10877.1 - 5.2e-19 68.9 0.0 6.2e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB10877.1 - 5.1e-08 33.5 0.0 6.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB10877.1 - 0.003 18.0 0.0 0.0037 17.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fer4 PF00037.27 EGB10877.1 - 0.19 11.6 0.8 0.19 11.6 0.8 1.6 2 0 0 2 2 2 0 4Fe-4S binding domain 2OG-FeII_Oxy_3 PF13640.6 EGB10878.1 - 5.2e-19 68.9 0.0 6.2e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB10878.1 - 5.1e-08 33.5 0.0 6.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB10878.1 - 0.003 18.0 0.0 0.0037 17.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fer4 PF00037.27 EGB10878.1 - 0.19 11.6 0.8 0.19 11.6 0.8 1.6 2 0 0 2 2 2 0 4Fe-4S binding domain WW PF00397.26 EGB10881.1 - 4.8e-08 33.0 1.4 1e-07 31.9 1.4 1.6 1 0 0 1 1 1 1 WW domain Methyltransf_25 PF13649.6 EGB10881.1 - 0.0011 19.6 0.0 0.0034 18.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGB10881.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ank_2 PF12796.7 EGB10882.1 - 2.6e-38 130.5 10.2 3.2e-12 46.9 1.2 4.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EGB10882.1 - 4.2e-30 102.8 37.0 5.4e-06 26.6 0.3 9.1 8 1 1 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 EGB10882.1 - 1.3e-27 95.8 9.4 5.1e-05 23.7 0.1 7.1 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10882.1 - 1.1e-24 83.8 11.5 0.035 14.6 0.1 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EGB10882.1 - 4e-24 84.4 26.7 2.5e-06 27.6 1.2 7.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Maff2 PF12750.7 EGB10882.1 - 0.024 14.4 0.2 0.077 12.8 0.1 1.9 1 1 0 1 1 1 0 Maff2 family APS_kinase PF01583.20 EGB10883.1 - 6.7e-57 191.8 0.0 7.7e-57 191.6 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EGB10883.1 - 5e-05 23.5 0.0 7.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB10883.1 - 0.00028 21.4 0.0 0.00033 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGB10883.1 - 0.0025 18.3 0.0 0.0042 17.6 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EGB10883.1 - 0.0031 17.2 0.2 0.0066 16.2 0.1 1.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGB10883.1 - 0.005 16.2 0.1 0.0075 15.6 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 EGB10883.1 - 0.053 13.6 0.0 0.074 13.1 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 EGB10883.1 - 0.054 13.1 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KTI12 PF08433.10 EGB10883.1 - 0.066 12.7 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EGB10883.1 - 0.1 12.3 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB10883.1 - 0.15 12.0 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGB10883.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Sterol_MT_C PF08498.10 EGB10884.1 - 1.1e-26 92.9 0.2 2.6e-26 91.7 0.2 1.6 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.20 EGB10884.1 - 4e-11 42.7 0.0 9.8e-11 41.4 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EGB10884.1 - 1.2e-10 41.9 0.0 3.3e-09 37.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB10884.1 - 7.5e-10 38.9 0.0 1.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB10884.1 - 8e-09 36.1 0.0 7e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB10884.1 - 1.1e-08 35.0 0.0 2.2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10884.1 - 1.1e-05 26.1 0.0 2.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB10884.1 - 0.0022 17.3 0.0 0.012 15.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Nuc_deoxyri_tr3 PF11071.8 EGB10885.1 - 1.4e-44 151.5 0.0 7.7e-43 145.9 0.0 2.0 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase YtoQ Nuc_deoxyri_tr2 PF15891.5 EGB10885.1 - 1.5e-05 25.2 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 EGB10885.1 - 0.081 12.9 0.0 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase UPF0020 PF01170.18 EGB10886.1 - 3.1e-14 53.1 0.0 3.1e-12 46.6 0.1 2.9 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EGB10886.1 - 1.8e-05 24.6 0.0 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 EGB10886.1 - 0.12 11.6 0.0 14 4.9 0.0 2.1 2 0 0 2 2 2 0 N-6 DNA Methylase EF-hand_7 PF13499.6 EGB10887.1 - 0.0069 16.8 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair CCDC53 PF10152.9 EGB10887.1 - 0.32 11.4 10.9 5.2 7.5 10.9 2.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex OTCace_N PF02729.21 EGB10888.1 - 1.2e-33 116.2 0.0 4.4e-33 114.4 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EGB10888.1 - 5.9e-31 107.7 0.0 8.1e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Arylsulfotrans PF05935.11 EGB10889.1 - 1.9e-13 50.1 0.1 7.4e-13 48.2 0.1 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF3108 PF11306.8 EGB10889.1 - 0.067 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Ras PF00071.22 EGB10892.1 - 8.7e-35 119.7 0.0 1.2e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB10892.1 - 3.4e-22 78.9 0.0 7.5e-22 77.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB10892.1 - 1.2e-08 34.6 0.0 2e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGB10892.1 - 0.00091 18.5 0.5 2 7.5 0.1 3.0 2 1 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGB10892.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 EGB10892.1 - 0.043 13.2 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 EGB10892.1 - 0.097 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGB10892.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Myb_DNA-bind_6 PF13921.6 EGB10893.1 - 3.6e-18 65.6 0.6 3.9e-18 65.5 0.6 1.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGB10893.1 - 2.1e-16 59.8 6.4 8.6e-16 57.9 0.6 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EGB10893.1 - 0.038 14.2 0.3 0.095 12.9 0.1 1.8 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EGB10893.1 - 0.28 11.6 3.3 0.53 10.7 0.4 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sel1 PF08238.12 EGB10894.1 - 2e-25 88.6 9.5 1.2e-09 38.5 0.3 4.4 4 1 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB10894.1 - 1e-05 26.0 5.9 0.00026 21.6 1.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGB10894.1 - 0.0006 19.6 1.8 0.0006 19.6 1.8 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10894.1 - 0.0017 18.6 2.5 0.0017 18.6 2.5 3.6 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB10894.1 - 0.0023 17.7 1.4 0.0023 17.7 1.4 5.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10894.1 - 0.025 14.7 0.5 0.025 14.7 0.5 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TetR_C_11 PF16859.5 EGB10894.1 - 0.15 12.4 0.1 9.3 6.6 0.0 2.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TPR_17 PF13431.6 EGB10894.1 - 0.54 10.8 4.4 1 9.9 0.3 3.4 4 2 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 EGB10895.1 - 7.2e-23 80.5 0.1 8.3e-23 80.3 0.1 1.0 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EGB10895.1 - 0.042 13.7 0.4 0.98 9.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PhyH PF05721.13 EGB10896.1 - 0.0062 16.8 0.1 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD-oxidase_C PF02913.19 EGB10897.1 - 4.1e-56 190.4 2.0 1e-55 189.1 2.0 1.7 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGB10897.1 - 6.7e-34 116.6 2.5 1.7e-33 115.3 2.5 1.7 1 0 0 1 1 1 1 FAD binding domain TatD_DNase PF01026.21 EGB10898.1 - 4.1e-38 131.2 0.0 4.8e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Ank_4 PF13637.6 EGB10900.1 - 3e-20 72.3 2.6 5.6e-13 49.1 0.1 4.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB10900.1 - 1.3e-16 61.0 3.7 1.9e-13 50.8 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGB10900.1 - 8.8e-14 51.2 15.7 2.8e-06 27.5 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeat LRR_6 PF13516.6 EGB10900.1 - 1.1e-13 50.1 8.4 0.0048 16.9 0.0 7.5 8 0 0 8 8 8 3 Leucine Rich repeat Ank_5 PF13857.6 EGB10900.1 - 2.1e-13 50.2 0.6 3.5e-10 39.9 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10900.1 - 3.7e-13 48.4 1.1 7.1e-06 26.0 0.0 5.0 3 1 1 4 4 4 3 Ankyrin repeat LRR_4 PF12799.7 EGB10900.1 - 0.00023 21.5 0.0 3.2 8.3 0.0 3.9 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGB10900.1 - 0.0069 16.1 0.1 6 6.7 0.0 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EGB10900.1 - 0.045 14.3 0.6 37 5.4 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat DUF4116 PF13475.6 EGB10901.1 - 3.7e-20 71.4 0.0 8.3e-08 31.8 0.0 2.5 1 1 2 3 3 3 3 Domain of unknown function (DUF4116) FumaraseC_C PF10415.9 EGB10901.1 - 0.016 15.7 0.3 0.63 10.5 0.0 2.6 1 1 1 2 2 2 0 Fumarase C C-terminus KLRAQ PF10205.9 EGB10901.1 - 0.045 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Histone_H2A_C PF16211.5 EGB10902.1 - 8.3e-20 70.2 1.4 2e-19 69.0 1.4 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB10902.1 - 5.1e-12 46.3 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB10902.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB10903.1 - 6.1e-53 178.7 1.1 6.8e-53 178.5 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGB10903.1 - 0.00076 20.1 3.0 0.00098 19.7 3.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGB10903.1 - 0.00088 19.4 0.3 0.0014 18.7 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB10903.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGB10903.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGB10903.1 - 0.032 14.3 0.1 0.057 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit cobW PF02492.19 EGB10904.1 - 6e-50 169.3 1.5 9.4e-50 168.6 1.5 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB10904.1 - 1.8e-20 72.7 0.0 3.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 EGB10904.1 - 0.0026 17.7 0.3 0.0081 16.1 0.1 2.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 EGB10904.1 - 0.003 17.1 0.2 2.9 7.4 0.1 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB10904.1 - 0.0059 16.5 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EGB10904.1 - 0.0069 16.9 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 EGB10904.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB10904.1 - 0.014 15.4 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EGB10904.1 - 0.025 14.3 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EGB10904.1 - 0.028 14.5 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EGB10904.1 - 0.04 12.9 0.6 6.1 5.7 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EGB10904.1 - 0.055 13.7 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGB10904.1 - 0.097 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EGB10904.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Metalloenzyme PF01676.18 EGB10904.1 - 0.28 10.5 1.3 0.46 9.8 1.3 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Ank_2 PF12796.7 EGB10905.1 - 4e-36 123.5 4.3 3.2e-12 46.9 0.1 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10905.1 - 3.4e-29 100.8 0.6 1.4e-08 35.1 0.0 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB10905.1 - 6.5e-22 77.3 4.4 3.1e-08 33.7 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10905.1 - 7.5e-19 65.9 2.5 0.0031 17.9 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EGB10905.1 - 3.4e-16 58.9 3.6 0.0064 16.9 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EGB10906.1 - 9.3e-22 77.4 0.8 1.1e-13 51.5 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10906.1 - 1.2e-17 64.0 0.1 2e-07 31.4 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10906.1 - 1.1e-15 56.1 1.5 0.0011 19.2 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EGB10906.1 - 1.2e-15 57.1 6.1 0.00024 21.4 0.3 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGB10906.1 - 1.4e-15 57.1 7.3 1.8e-05 24.9 0.3 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) zf-MYND PF01753.18 EGB10907.1 - 1.7e-10 40.8 17.5 2.3e-10 40.4 17.5 1.2 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGB10907.1 - 0.43 10.9 12.1 0.67 10.3 12.1 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Gly-zipper_Omp PF13488.6 EGB10908.1 - 0.017 15.1 9.9 0.017 15.1 9.9 4.6 3 1 1 4 4 4 0 Glycine zipper STAS PF01740.21 EGB10909.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 STAS domain Gp_dh_C PF02800.20 EGB10910.1 - 6.3e-65 217.6 0.0 9.4e-65 217.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGB10910.1 - 6.4e-28 97.1 0.0 1.4e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SNase PF00565.17 EGB10910.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal nuclease homologue DUF296 PF03479.15 EGB10911.1 - 5.6e-27 94.2 0.2 6.6e-27 94.0 0.2 1.1 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain FAM183 PF14886.6 EGB10912.1 - 3.4e-13 50.3 0.0 5.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 FAM183A and FAM183B related TauD PF02668.16 EGB10913.1 - 8.1e-21 75.0 0.8 2.9e-20 73.2 0.8 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGB10913.1 - 0.00058 20.4 0.0 0.0014 19.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGB10913.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 CsiD UPF0126 PF03458.13 EGB10914.1 - 8.1e-35 118.6 20.7 2.2e-18 65.9 10.4 2.3 2 0 0 2 2 2 2 UPF0126 domain Hydrolase_6 PF13344.6 EGB10915.1 - 3.3e-23 81.7 0.0 6.7e-23 80.7 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB10915.1 - 4.2e-16 58.8 2.0 3.8e-15 55.7 0.1 2.7 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGB10915.1 - 3.6e-05 24.2 2.8 0.02 15.2 0.1 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGB10915.1 - 0.00069 19.7 0.0 0.0031 17.6 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NAD_binding_2 PF03446.15 EGB10916.1 - 9.7e-36 123.3 0.8 1.7e-35 122.6 0.8 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGB10916.1 - 1.5e-21 76.8 3.1 3.2e-21 75.8 3.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGB10916.1 - 1.7e-06 28.5 0.0 4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGB10916.1 - 0.00012 22.2 0.1 0.0002 21.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGB10916.1 - 0.0002 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EGB10916.1 - 0.00058 19.8 0.1 0.00096 19.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EGB10916.1 - 0.0051 16.5 0.1 0.0096 15.6 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EGB10916.1 - 0.015 15.5 0.1 0.04 14.2 0.1 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EGB10916.1 - 0.04 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 EGB10916.1 - 0.062 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 EGB10916.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus fn3 PF00041.21 EGB10918.1 - 6.1e-06 26.5 0.0 1.8e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain WW PF00397.26 EGB10918.1 - 1.6e-05 24.9 10.1 0.028 14.5 0.8 3.5 3 0 0 3 3 3 2 WW domain Kelch_1 PF01344.25 EGB10918.1 - 0.002 17.7 0.3 3.4 7.3 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Melibiase_2 PF16499.5 EGB10919.1 - 2.9e-45 154.6 5.5 8.1e-45 153.2 5.5 1.6 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGB10919.1 - 4.3e-07 29.9 0.0 8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGB10919.1 - 1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Melibiase TPT PF03151.16 EGB10920.1 - 1.2e-20 74.1 9.9 1.5e-20 73.7 9.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB10920.1 - 0.00042 20.5 23.7 0.0018 18.4 7.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family 2TM PF13239.6 EGB10920.1 - 0.0069 16.7 0.1 0.0069 16.7 0.1 3.2 3 1 0 3 3 3 1 2TM domain UPF0060 PF02694.15 EGB10920.1 - 0.25 11.6 0.1 0.25 11.6 0.1 3.0 2 2 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family cobW PF02492.19 EGB10921.1 - 1.5e-33 115.9 0.4 2.5e-33 115.1 0.4 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB10921.1 - 4e-16 58.7 0.0 1.1e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain PriC PF07445.12 EGB10921.1 - 0.014 15.4 0.7 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Primosomal replication protein priC FXMRP1_C_core PF12235.8 EGB10921.1 - 7 7.3 7.9 12 6.5 7.3 1.7 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal 2OG-FeII_Oxy_3 PF13640.6 EGB10923.1 - 2e-08 35.0 0.0 5.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LRR_6 PF13516.6 EGB10923.1 - 2.1e-07 30.5 9.7 0.049 13.7 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 EGB10923.1 - 0.0034 17.1 0.1 2.7 7.8 0.0 3.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 EGB10923.1 - 0.067 13.8 0.0 60 4.8 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat DUF21 PF01595.20 EGB10923.1 - 0.44 10.2 1.5 0.88 9.2 1.5 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain LRR_4 PF12799.7 EGB10923.1 - 2.6 8.6 4.5 14 6.2 0.0 3.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DHC_N1 PF08385.12 EGB10925.1 - 7.4e-184 612.5 1.2 7.4e-184 612.5 1.2 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EGB10925.1 - 1.7e-135 451.2 0.3 1.3e-132 441.7 0.0 3.9 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 EGB10925.1 - 2.7e-77 258.8 0.0 1.7e-76 256.2 0.0 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region DHC_N2 PF08393.13 EGB10925.1 - 4.1e-75 253.3 19.6 1.4e-65 222.0 1.8 4.0 4 1 1 5 5 3 2 Dynein heavy chain, N-terminal region 2 MT PF12777.7 EGB10925.1 - 8.5e-73 245.3 12.7 1.5e-72 244.5 12.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EGB10925.1 - 3.8e-61 207.0 0.5 1.9e-52 178.4 0.2 2.6 1 1 1 2 2 2 2 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGB10925.1 - 5.2e-60 202.1 0.1 7.3e-53 178.8 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_8 PF12780.7 EGB10925.1 - 1.9e-56 191.3 1.1 7.8e-33 113.9 0.0 3.8 3 1 1 4 4 3 2 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 EGB10925.1 - 7.4e-46 156.0 0.0 1.5e-45 155.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB10925.1 - 2.8e-36 124.2 0.0 9.9e-36 122.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGB10925.1 - 4.4e-21 75.3 0.0 1.3e-20 73.8 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGB10925.1 - 5.8e-18 64.9 0.1 3e-17 62.6 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB10925.1 - 3.4e-17 62.7 0.0 6.8e-08 32.6 0.0 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) EF-hand_7 PF13499.6 EGB10925.1 - 1.5e-12 47.8 1.3 2.5e-08 34.2 0.2 4.6 4 1 0 4 4 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB10925.1 - 4.5e-08 32.1 11.2 0.00047 19.5 0.1 5.6 6 0 0 6 6 4 3 EF hand AAA_22 PF13401.6 EGB10925.1 - 6.7e-08 32.9 0.2 0.42 10.9 0.0 4.7 4 0 0 4 4 4 2 AAA domain EF-hand_6 PF13405.6 EGB10925.1 - 8.6e-08 31.5 4.3 0.00033 20.4 0.1 5.5 5 0 0 5 5 5 1 EF-hand domain Mg_chelatase PF01078.21 EGB10925.1 - 1.9e-07 30.7 0.7 0.011 15.2 0.0 3.7 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 EGB10925.1 - 8.5e-07 29.5 0.2 0.57 10.6 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGB10925.1 - 8.7e-07 29.5 0.1 0.87 10.1 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_19 PF13245.6 EGB10925.1 - 8e-05 23.0 0.6 2.5 8.4 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGB10925.1 - 8.7e-05 22.3 1.6 1.6 8.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain EF-hand_8 PF13833.6 EGB10925.1 - 9.7e-05 22.1 7.5 0.00016 21.5 0.6 4.0 5 0 0 5 5 2 1 EF-hand domain pair AAA_16 PF13191.6 EGB10925.1 - 0.00017 22.0 8.9 0.69 10.3 0.0 5.5 6 0 0 6 6 3 2 AAA ATPase domain ABC_tran PF00005.27 EGB10925.1 - 0.0002 21.9 0.4 0.14 12.7 0.0 3.6 3 0 0 3 3 2 1 ABC transporter DUF815 PF05673.13 EGB10925.1 - 0.00059 19.1 0.2 2.2 7.4 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGB10925.1 - 0.0021 18.4 0.2 2.9 8.3 0.0 3.4 3 0 0 3 3 3 1 RNA helicase EF-hand_5 PF13202.6 EGB10925.1 - 0.0022 17.4 8.7 0.41 10.2 0.2 5.0 5 0 0 5 5 5 1 EF hand TsaE PF02367.17 EGB10925.1 - 0.0022 18.0 2.1 6.2 6.8 0.1 4.0 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGB10925.1 - 0.003 17.7 0.1 11 6.2 0.0 4.2 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 EGB10925.1 - 0.006 16.8 0.1 2.1 8.6 0.0 3.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGB10925.1 - 0.0074 16.0 0.3 9.5 5.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EGB10925.1 - 0.017 14.9 0.1 4.9 6.8 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EGB10925.1 - 0.021 14.6 1.0 0.89 9.3 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EGB10925.1 - 0.038 13.9 0.2 4.6 7.1 0.1 3.3 3 0 0 3 3 3 0 NACHT domain SRP54 PF00448.22 EGB10925.1 - 0.043 13.4 5.6 2.5 7.7 0.1 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 EGB10925.1 - 0.064 12.1 1.5 0.64 8.9 0.0 2.6 3 0 0 3 3 2 0 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 EGB10925.1 - 0.094 12.6 0.1 8.7 6.2 0.0 3.0 3 0 0 3 3 2 0 RsgA GTPase Rad17 PF03215.15 EGB10925.1 - 0.1 12.5 0.1 1.5 8.8 0.1 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_29 PF13555.6 EGB10925.1 - 0.12 12.2 2.3 42 4.0 0.1 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EGB10925.1 - 3.7 7.2 4.5 4.1 7.1 0.1 2.9 3 1 1 4 4 2 0 Viral (Superfamily 1) RNA helicase Thr_synth_N PF14821.6 EGB10926.1 - 3.4e-26 91.3 0.0 9.2e-26 89.9 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EGB10926.1 - 1.1e-18 67.7 0.0 1.7e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EF-hand_1 PF00036.32 EGB10927.1 - 1.1e-11 43.4 0.1 1e-05 24.7 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB10927.1 - 6.6e-10 38.1 0.0 1.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB10927.1 - 9.4e-10 38.8 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB10927.1 - 2.7e-08 33.0 0.0 1.7e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB10927.1 - 5.6e-08 32.5 0.1 0.0047 16.7 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB10927.1 - 0.081 13.3 0.0 0.097 13.0 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region 2-oxoacid_dh PF00198.23 EGB10928.1 - 2.1e-62 210.6 0.0 3.3e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EGB10928.1 - 4.6e-17 62.1 7.9 4.3e-08 33.4 0.2 2.8 1 1 1 2 2 2 2 e3 binding domain Biotin_lipoyl PF00364.22 EGB10928.1 - 1.3e-15 56.9 0.5 1.3e-15 56.9 0.5 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGB10928.1 - 0.0089 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like Pkinase PF00069.25 EGB10929.1 - 2.9e-46 158.0 0.0 8.4e-46 156.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10929.1 - 6.3e-15 55.2 0.0 7.6e-14 51.6 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB10929.1 - 5.4e-06 25.9 0.0 7.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Myb_DNA-binding PF00249.31 EGB10930.1 - 1.3e-12 47.7 0.0 1.4e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB10930.1 - 0.0024 17.8 0.0 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EGB10930.1 - 0.0046 17.2 0.0 0.0054 16.9 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cytochrom_C PF00034.21 EGB10931.1 - 2.1e-12 48.0 0.1 3e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGB10931.1 - 7.8e-06 26.1 3.5 3.9e-05 23.9 3.5 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGB10931.1 - 0.0088 15.8 0.6 0.038 13.7 0.3 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Pkinase PF00069.25 EGB10932.1 - 1.3e-75 254.2 0.0 1.5e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10932.1 - 4e-31 108.3 0.0 4.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB10932.1 - 0.00054 19.4 0.0 0.0014 18.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB10932.1 - 0.0025 17.2 0.2 0.0035 16.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB10932.1 - 0.0071 15.2 0.0 0.0098 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGB10932.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EGB10932.1 - 0.086 12.8 0.2 2.6 7.9 0.1 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGB10932.1 - 0.095 12.3 0.0 0.13 11.8 0.0 1.3 1 1 0 1 1 1 0 RIO1 family CsgA PF17334.2 EGB10932.1 - 0.099 13.4 0.0 1.8 9.4 0.0 2.4 2 0 0 2 2 2 0 Minor curli fiber component A Pkinase PF00069.25 EGB10933.1 - 2.1e-13 50.3 0.0 2.6e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Rhomboid PF01694.22 EGB10934.1 - 4.4e-19 69.0 8.5 4.7e-19 68.9 8.5 1.0 1 0 0 1 1 1 1 Rhomboid family V_ATPase_I PF01496.19 EGB10934.1 - 0.0034 15.4 0.3 0.0038 15.2 0.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AAA PF00004.29 EGB10935.1 - 6.1e-39 133.5 0.0 1.3e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB10935.1 - 6.5e-15 54.7 4.3 1.6e-13 50.2 0.9 4.0 3 2 1 4 4 4 1 AAA+ lid domain Vps4_C PF09336.10 EGB10935.1 - 1.6e-09 37.6 0.0 1e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EGB10935.1 - 3.3e-05 23.7 0.0 5.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGB10935.1 - 5.7e-05 23.1 0.0 0.0026 17.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGB10935.1 - 0.00022 21.4 0.0 0.00052 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGB10935.1 - 0.00067 19.1 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGB10935.1 - 0.00086 19.5 0.0 0.0065 16.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGB10935.1 - 0.0015 17.8 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EGB10935.1 - 0.0019 17.8 0.0 0.011 15.3 0.1 2.1 2 1 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGB10935.1 - 0.0027 17.5 0.0 0.0066 16.2 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 EGB10935.1 - 0.003 18.0 0.2 0.0058 17.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EGB10935.1 - 0.0033 17.4 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGB10935.1 - 0.0048 17.3 0.0 0.039 14.3 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EGB10935.1 - 0.0048 16.6 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB10935.1 - 0.0049 17.1 0.1 0.018 15.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB10935.1 - 0.0052 17.3 0.3 0.035 14.7 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGB10935.1 - 0.017 15.4 0.1 0.053 13.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 EGB10935.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 EGB10935.1 - 0.057 13.4 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EGB10935.1 - 0.059 12.9 0.3 0.22 11.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGB10935.1 - 0.083 12.6 0.0 0.38 10.4 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain NACHT PF05729.12 EGB10935.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 EGB10935.1 - 0.099 13.1 0.0 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGB10935.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UQ_con PF00179.26 EGB10936.1 - 7e-16 58.2 0.0 8.4e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3510 PF12022.8 EGB10937.1 - 2.7e-11 43.9 0.0 6.9e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 EGB10937.1 - 8.4e-06 25.9 1.4 8.4e-06 25.9 1.4 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 cNMP_binding PF00027.29 EGB10937.1 - 8.6e-05 22.5 0.3 0.00062 19.8 0.0 2.5 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain Helicase_C PF00271.31 EGB10938.1 - 1.1e-18 67.6 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fe-S_biosyn PF01521.20 EGB10940.1 - 3.3e-11 43.4 0.0 3.6e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ank_3 PF13606.6 EGB10942.1 - 4.7e-16 57.3 0.5 4.3e-05 23.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EGB10942.1 - 7.6e-15 55.3 0.3 1.4e-09 38.4 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB10942.1 - 1.2e-13 51.3 2.0 6.7e-06 26.5 0.2 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB10942.1 - 2.5e-13 49.8 1.5 0.0011 19.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB10942.1 - 5.3e-10 39.4 2.1 0.00069 19.9 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DRIM PF07539.12 EGB10943.1 - 1.4e-60 205.4 0.0 4.5e-60 203.7 0.0 1.8 1 0 0 1 1 1 1 Down-regulated in metastasis Radial_spoke PF04712.12 EGB10943.1 - 2.6 6.9 8.7 0.11 11.4 1.5 1.9 2 0 0 2 2 2 0 Radial spokehead-like protein DUF2052 PF09747.9 EGB10943.1 - 4.2 7.5 13.4 0.27 11.4 2.2 2.9 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) WD40 PF00400.32 EGB10944.1 - 1.7e-20 73.0 0.8 2.5e-11 43.9 0.4 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGB10944.1 - 2.1e-06 26.9 0.0 0.0066 15.4 0.0 2.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB10944.1 - 0.0037 17.2 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGB10944.1 - 0.0038 17.5 0.0 1.7 9.0 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB10944.1 - 0.011 14.4 0.4 0.11 11.1 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 EGB10944.1 - 0.052 13.5 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 EGB10944.1 - 0.29 11.7 5.3 6.3 7.4 0.1 3.0 2 1 0 2 2 2 0 PQQ-like domain AMP-binding PF00501.28 EGB10945.1 - 5.4e-81 272.3 0.1 7e-81 272.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB10945.1 - 2.3e-21 76.6 0.5 4.7e-21 75.5 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGB10945.1 - 8.3e-18 64.1 1.8 2.2e-17 62.7 1.8 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus SNF2_N PF00176.23 EGB10946.1 - 9.9e-73 244.8 0.0 1.6e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGB10946.1 - 1.9e-32 111.7 0.0 4.6e-31 107.2 0.0 2.4 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.31 EGB10946.1 - 7.5e-18 64.9 0.0 1.6e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB10946.1 - 2.3e-09 37.5 0.0 7.2e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 EGB10946.1 - 3e-09 37.1 2.7 3e-09 37.1 2.7 2.6 3 0 0 3 3 3 1 HMG (high mobility group) box DEAD PF00270.29 EGB10946.1 - 0.00014 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGB10946.1 - 0.0012 18.6 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 EGB10946.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-bind_6 PF13921.6 EGB10946.1 - 0.057 13.7 0.0 1.4 9.2 0.0 2.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain HMG_box_2 PF09011.10 EGB10946.1 - 0.13 12.9 2.6 0.54 10.9 2.6 2.0 1 0 0 1 1 1 0 HMG-box domain DUF4259 PF14078.6 EGB10946.1 - 0.22 12.3 1.7 0.71 10.6 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Aldo_ket_red PF00248.21 EGB10947.1 - 9.6e-16 57.8 0.0 4.2e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family NAD_binding_1 PF00175.21 EGB10948.1 - 1.2e-18 67.8 0.0 1.4e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Pro_isomerase PF00160.21 EGB10949.1 - 7.2e-45 153.1 0.0 8.3e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sina PF03145.16 EGB10950.1 - 4.3e-07 30.1 0.0 6.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Seven in absentia protein family SAP PF02037.27 EGB10950.1 - 0.00024 20.8 0.5 0.00056 19.6 0.3 1.8 2 0 0 2 2 2 1 SAP domain zf-Di19 PF05605.12 EGB10950.1 - 0.015 15.6 0.6 12 6.3 0.0 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 EGB10950.1 - 0.041 13.7 2.4 0.36 10.7 0.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGB10950.1 - 0.043 13.8 2.2 0.31 11.1 1.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zinc-ribbons_6 PF07191.12 EGB10950.1 - 0.22 11.5 1.3 0.6 10.1 1.3 1.7 1 1 0 1 1 1 0 zinc-ribbons zf-C3HC4_3 PF13920.6 EGB10950.1 - 0.27 11.1 3.9 0.81 9.6 1.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 EGB10950.1 - 0.58 10.9 9.7 1.9 9.3 0.6 3.0 2 1 1 3 3 3 0 TRAF-type zinc finger DUF2457 PF10446.9 EGB10950.1 - 1.2 8.3 4.6 2.5 7.1 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_ligase_ZBD PF03119.16 EGB10950.1 - 1.5 8.9 11.8 6.5 6.9 0.3 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 EGB10950.1 - 2.7 8.1 6.0 28 4.8 6.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon Sel1 PF08238.12 EGB10951.1 - 1.4e-18 66.9 10.2 3.3e-06 27.6 0.0 4.4 4 1 0 4 4 4 4 Sel1 repeat MIT PF04212.18 EGB10951.1 - 0.0063 16.6 0.6 0.0063 16.6 0.6 2.7 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EGB10951.1 - 0.012 15.4 3.9 0.34 10.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10951.1 - 0.05 13.9 3.3 0.78 10.1 2.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF977 PF06163.11 EGB10951.1 - 0.16 11.9 0.2 2.2 8.2 0.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF977) TPR_5 PF12688.7 EGB10951.1 - 0.32 11.3 3.3 45 4.3 0.1 2.9 2 1 1 3 3 3 0 Tetratrico peptide repeat TPR_1 PF00515.28 EGB10951.1 - 1.5 8.8 10.9 0.54 10.2 0.9 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10951.1 - 3 8.3 9.2 2.2 8.7 0.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB10951.1 - 6.6 7.1 17.7 0.5 10.6 1.4 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat HWE_HK PF07536.14 EGB10952.1 - 0.033 14.9 0.1 0.081 13.6 0.1 1.6 1 0 0 1 1 1 0 HWE histidine kinase Prenyltrans PF00432.21 EGB10952.1 - 0.16 11.8 5.4 0.35 10.6 2.8 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Ank_2 PF12796.7 EGB10954.1 - 1.3e-13 51.3 0.1 2.4e-13 50.5 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB10954.1 - 2.7e-13 49.9 0.9 8.7e-07 29.1 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB10954.1 - 6.3e-13 47.7 0.3 7e-05 22.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGB10954.1 - 1.9e-12 47.0 1.0 8.6e-06 26.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGB10954.1 - 4.3e-12 46.3 0.7 3.1e-07 30.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Cas_NE0113 PF09623.10 EGB10954.1 - 0.12 12.1 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Got1 PF04178.12 EGB10955.1 - 4.7e-26 91.4 12.9 7.9e-26 90.7 12.9 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family LtrA PF06772.11 EGB10955.1 - 0.0021 17.4 5.1 0.0023 17.2 5.1 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF1772 PF08592.11 EGB10955.1 - 0.24 11.7 8.0 0.57 10.5 7.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) NIF PF03031.18 EGB10956.1 - 1.7e-11 44.1 0.0 3.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PA PF02225.22 EGB10956.1 - 0.047 13.7 0.3 0.37 10.8 0.2 2.3 2 0 0 2 2 2 0 PA domain DAGK_acc PF00609.19 EGB10957.1 - 2.9e-34 118.7 0.0 4.4e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EGB10957.1 - 2e-20 72.6 0.0 3.4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Arylsulfotrans PF05935.11 EGB10958.1 - 2.5e-09 36.5 0.0 4.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB10958.1 - 0.00026 20.5 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Peptidase_M24 PF00557.24 EGB10960.1 - 3.3e-52 177.2 0.1 4.5e-52 176.8 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGB10960.1 - 3.6e-23 81.6 0.0 6.7e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TRM PF02005.16 EGB10961.1 - 6.1e-108 361.3 0.0 7e-108 361.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EGB10961.1 - 0.00079 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EGB10961.1 - 0.0068 17.1 0.3 0.019 15.6 0.3 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB10961.1 - 0.098 12.4 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain FKBP_C PF00254.28 EGB10962.1 - 8.5e-29 99.7 0.0 1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 EGB10963.1 - 1.2e-20 74.0 0.0 2.6e-20 72.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10963.1 - 1.2e-12 47.6 0.0 2.3e-11 43.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase TBPIP PF07106.13 EGB10963.1 - 2.7e-06 27.2 0.0 5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Kdo PF06293.14 EGB10963.1 - 0.00034 20.0 0.0 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_17 PF13431.6 EGB10963.1 - 0.0035 17.6 1.6 3.2 8.3 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB10963.1 - 0.013 15.7 3.0 3.8 8.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.11 EGB10963.1 - 0.017 13.2 6.4 0.023 12.8 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.9 EGB10963.1 - 0.019 13.5 7.9 0.033 12.7 7.9 1.4 1 0 0 1 1 1 0 Macoilin family TPR_1 PF00515.28 EGB10963.1 - 0.097 12.5 0.0 0.097 12.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat QH-AmDH_gamma PF08992.11 EGB10963.1 - 0.17 11.9 0.3 0.43 10.6 0.3 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit TPR_2 PF07719.17 EGB10963.1 - 0.19 12.0 0.1 0.19 12.0 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Merozoite_SPAM PF07133.11 EGB10963.1 - 1.5 8.7 24.0 2.6 8.0 24.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PI3K_1B_p101 PF10486.9 EGB10963.1 - 2.8 5.6 10.0 4.1 5.1 10.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LAT PF15234.6 EGB10963.1 - 4 7.1 18.0 2.3 7.9 15.4 1.8 1 1 0 1 1 1 0 Linker for activation of T-cells TFIIF_alpha PF05793.12 EGB10963.1 - 4.5 5.8 36.8 7.7 5.0 36.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Fer2 PF00111.27 EGB10964.1 - 9e-06 25.6 1.0 1.1e-05 25.3 1.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 EGB10964.1 - 0.05 13.2 0.1 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 Magnetochrome domain CDC24_OB3 PF17244.2 EGB10964.1 - 0.19 11.4 0.2 0.19 11.4 0.2 1.0 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 RCC1 PF00415.18 EGB10965.1 - 4.3e-60 200.1 16.8 2.3e-11 44.1 0.1 8.9 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB10965.1 - 1.6e-24 85.1 51.0 1e-06 28.4 3.3 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat AF-4 PF05110.13 EGB10965.1 - 0.4 8.7 0.6 0.61 8.1 0.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glycos_transf_1 PF00534.20 EGB10966.1 - 5.2e-13 48.9 0.0 3.7e-12 46.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGB10966.1 - 1.4e-11 44.9 0.0 2.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGB10966.1 - 2e-09 37.7 0.0 6.7e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 MFS_1 PF07690.16 EGB10967.1 - 2e-12 46.7 37.8 3.9e-07 29.3 14.9 2.9 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB10967.1 - 1.8e-06 27.1 1.3 1.8e-06 27.1 1.3 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGB10967.1 - 0.018 13.9 0.2 0.06 12.2 0.0 2.1 1 1 2 3 3 3 0 MFS_1 like family Kinesin PF00225.23 EGB10968.1 - 8.3e-78 261.6 0.0 2.1e-77 260.3 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGB10968.1 - 4.4e-13 49.4 0.0 8.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Cupin_8 PF13621.6 EGB10969.1 - 4.9e-23 82.2 0.0 7.7e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain NAD_binding_9 PF13454.6 EGB10969.1 - 1.4e-14 54.4 4.5 1.7e-08 34.6 0.1 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGB10969.1 - 3e-08 33.3 0.1 4.2e-07 29.5 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB10969.1 - 1.3e-07 31.1 0.6 5.1e-07 29.2 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EGB10969.1 - 2.3e-07 30.4 0.0 1.6e-05 24.3 0.0 2.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Cupin_4 PF08007.12 EGB10969.1 - 1.8e-05 24.4 0.0 9.8e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB10969.1 - 0.00012 21.7 0.0 0.0084 15.8 0.0 2.6 2 0 0 2 2 2 1 Cupin domain Pyr_redox PF00070.27 EGB10969.1 - 0.0017 18.9 0.1 1 10.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase JmjC PF02373.22 EGB10969.1 - 0.027 14.9 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase Orbi_VP6 PF01516.16 EGB10969.1 - 0.12 11.9 1.8 0.099 12.2 0.3 1.6 2 0 0 2 2 2 0 Orbivirus helicase VP6 MFS_1 PF07690.16 EGB10970.1 - 1.8e-36 125.8 39.9 1.8e-36 125.8 39.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_16 PF10294.9 EGB10972.1 - 2.6e-23 82.6 0.0 3.7e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EGB10972.1 - 0.00019 22.1 0.0 0.00038 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain HSP70 PF00012.20 EGB10972.1 - 0.0026 16.0 0.0 0.0036 15.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MTS PF05175.14 EGB10972.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EGB10972.1 - 0.043 13.6 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB10972.1 - 0.095 13.5 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 EGB10974.1 - 1e-35 123.0 0.0 1.6e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 EGB10974.1 - 5.4e-09 36.0 4.0 1e-08 35.1 4.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.6 EGB10974.1 - 8.7e-05 23.0 5.8 0.0027 18.1 0.0 3.5 3 1 0 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 EGB10974.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGB10974.1 - 0.00032 21.0 0.1 0.044 14.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGB10974.1 - 0.00082 19.4 0.1 0.0036 17.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 EGB10974.1 - 0.00083 19.1 1.6 0.0013 18.5 0.6 1.8 2 0 0 2 2 1 1 AAA+ lid domain TIP49 PF06068.13 EGB10974.1 - 0.0022 17.3 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 EGB10974.1 - 0.0073 15.9 0.0 0.091 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGB10974.1 - 0.01 15.3 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGB10974.1 - 0.031 14.5 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGB10974.1 - 0.034 13.9 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EGB10974.1 - 0.041 14.0 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EGB10974.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGB10974.1 - 0.077 12.7 0.0 0.37 10.5 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EGB10974.1 - 0.083 13.4 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGB10974.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EGB10974.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGB10974.1 - 0.28 10.5 0.1 1.3 8.3 0.0 1.8 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 EGB10974.1 - 0.3 10.6 0.0 0.48 9.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DEC-1_N PF04625.13 EGB10974.1 - 0.82 8.6 8.4 1.2 8.1 8.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DnaJ PF00226.31 EGB10975.1 - 4.1e-19 68.5 0.1 4.5e-19 68.3 0.1 1.0 1 0 0 1 1 1 1 DnaJ domain Phage_portal PF04860.12 EGB10975.1 - 0.09 12.0 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein Gln-synt_C PF00120.24 EGB10976.1 - 2e-79 267.1 0.0 3.7e-79 266.2 0.0 1.4 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGB10976.1 - 0.0092 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PRKCSH_1 PF13015.6 EGB10977.1 - 1.3e-16 60.7 0.1 1.4e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGB10978.1 - 2.5e-14 53.3 0.3 2.6e-14 53.2 0.3 1.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein URO-D PF01208.17 EGB10979.1 - 8.8e-82 275.0 0.0 9.9e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SBP_bac_5 PF00496.22 EGB10980.1 - 3.4e-09 36.1 0.1 3.8e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Dev_Cell_Death PF10539.9 EGB10981.1 - 3.5e-08 33.4 0.0 5.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Development and cell death domain SAM_2 PF07647.17 EGB10981.1 - 0.0034 17.4 0.0 26 5.0 0.0 4.3 5 0 0 5 5 5 2 SAM domain (Sterile alpha motif) DUF4332 PF14229.6 EGB10981.1 - 0.36 11.1 1.8 14 5.9 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4332) HHH_5 PF14520.6 EGB10981.1 - 1.4 9.6 5.6 1.7e+02 2.9 0.0 4.8 5 0 0 5 5 5 0 Helix-hairpin-helix domain MutS_V PF00488.21 EGB10982.1 - 3.1e-48 164.3 0.0 4e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 MutS domain V CobU PF02283.16 EGB10982.1 - 0.00087 18.9 0.2 0.66 9.5 0.0 2.1 1 1 1 2 2 2 2 Cobinamide kinase / cobinamide phosphate guanyltransferase NTPase_1 PF03266.15 EGB10982.1 - 0.024 14.6 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_27 PF13514.6 EGB10982.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.4 2 0 0 2 2 2 0 AAA domain Peptidase_C1 PF00112.23 EGB10983.1 - 1e-57 195.7 0.1 1.4e-57 195.3 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB10983.1 - 3.4e-07 30.6 0.0 5.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB10983.1 - 7.9e-07 28.2 0.1 4.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family ParA PF10609.9 EGB10984.1 - 7.9e-61 205.6 0.0 8.7e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGB10984.1 - 1.5e-14 54.1 0.1 1.7e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGB10984.1 - 8.4e-10 38.8 0.0 5.7e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EGB10984.1 - 4.2e-07 29.5 0.6 6e-07 29.0 0.1 1.5 2 0 0 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 EGB10984.1 - 0.00013 21.5 0.1 0.0022 17.5 0.3 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 EGB10984.1 - 0.00024 20.5 0.2 0.00052 19.4 0.2 1.5 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 EGB10984.1 - 0.00086 19.1 0.0 0.003 17.4 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ArsA_ATPase PF02374.15 EGB10984.1 - 0.0034 16.6 2.1 0.0073 15.5 1.3 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EGB10984.1 - 0.0047 16.4 0.1 0.0088 15.5 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EGB10984.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MeaB PF03308.16 EGB10984.1 - 0.03 13.3 2.1 0.037 13.0 2.1 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EGB10984.1 - 0.039 13.5 0.2 0.063 12.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 EGB10984.1 - 0.053 13.3 0.2 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EGB10984.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Pkinase PF00069.25 EGB10985.1 - 5.1e-49 167.0 0.0 5.8e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB10985.1 - 4.1e-26 91.8 0.0 5.2e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB10985.1 - 0.00028 20.3 0.3 0.00053 19.4 0.3 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB10985.1 - 0.0003 20.2 0.1 0.00045 19.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB10985.1 - 0.0037 17.2 0.2 0.01 15.7 0.1 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB10985.1 - 0.036 12.8 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase BBS2_Mid PF14783.6 EGB10986.1 - 7.8e-05 22.7 0.0 0.8 9.8 0.0 3.4 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 EGB10986.1 - 8e-05 21.6 0.0 0.0059 15.4 0.0 2.8 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal VCBS PF13517.6 EGB10986.1 - 0.041 14.5 0.1 0.42 11.2 0.1 2.4 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2982 PF11201.8 EGB10986.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) zf-CCCH PF00642.24 EGB10987.1 - 4.7e-09 35.9 1.1 8.1e-09 35.2 0.4 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGB10987.1 - 0.00067 19.6 0.2 0.0014 18.6 0.2 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EGB10987.1 - 0.037 14.7 0.1 0.085 13.6 0.1 1.5 1 0 0 1 1 1 0 Torus domain APG6_N PF17675.1 EGB10988.1 - 0.044 14.3 8.5 0.084 13.4 8.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Phage_lysozyme2 PF18013.1 EGB10988.1 - 0.17 11.9 0.0 0.5 10.4 0.0 1.7 1 0 0 1 1 1 0 Phage tail lysozyme DUF2968 PF11180.8 EGB10988.1 - 2.7 7.6 17.2 4.8 6.8 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) LRR_6 PF13516.6 EGB10989.1 - 3.8e-08 32.7 23.7 0.0019 18.1 0.1 7.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 EGB10989.1 - 0.0051 17.2 0.3 1.1 9.8 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB10989.1 - 0.038 14.5 0.2 28 5.8 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 EGB10989.1 - 0.16 11.7 0.2 7.1 6.5 0.0 3.5 3 1 0 3 3 3 0 Leucine rich repeat YgbB PF02542.16 EGB10990.1 - 1.1e-55 188.1 0.0 1.3e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 YgbB family ubiquitin PF00240.23 EGB10991.1 - 4e-38 129.0 0.3 5.2e-34 115.8 0.5 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EGB10991.1 - 3.3e-17 62.1 0.5 6.3e-16 58.0 0.8 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB10991.1 - 2e-06 28.1 0.1 5.3e-05 23.6 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB10991.1 - 0.0033 17.5 0.0 0.027 14.6 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGB10991.1 - 0.0038 17.1 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGB10991.1 - 0.0085 16.1 2.1 14 5.8 0.0 3.7 4 0 0 4 4 4 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGB10991.1 - 0.015 15.7 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 EGB10991.1 - 0.024 15.2 0.0 0.073 13.6 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF2597 PF10772.9 EGB10991.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) PH PF00169.29 EGB10992.1 - 3.1e-25 88.7 0.0 3.1e-09 37.3 0.0 3.5 3 0 0 3 3 3 3 PH domain FH2 PF02181.23 EGB10992.1 - 7.4e-19 68.1 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain SRP_TPR_like PF17004.5 EGB10992.1 - 2e-12 47.1 0.3 4.7e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat CCDC53 PF10152.9 EGB10992.1 - 1.7e-09 38.2 0.8 5.8e-09 36.5 0.8 1.9 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex PH_11 PF15413.6 EGB10992.1 - 2.7e-06 27.7 0.1 0.049 14.1 0.0 3.5 3 0 0 3 3 3 2 Pleckstrin homology domain SRP72 PF08492.12 EGB10992.1 - 0.00017 22.0 5.2 0.00017 22.0 5.2 3.2 4 0 0 4 4 4 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 EGB10992.1 - 0.0033 17.6 2.1 0.0033 17.6 2.1 3.8 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGB10992.1 - 0.12 12.5 4.9 26 5.1 0.1 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Drf_FH3 PF06367.16 EGB10992.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain Sel1 PF08238.12 EGB10993.1 - 3.8e-24 84.6 18.7 1.7e-07 31.7 0.1 5.4 5 0 0 5 5 5 5 Sel1 repeat TPR_10 PF13374.6 EGB10993.1 - 1.6 8.7 20.9 0.38 10.7 0.3 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB10993.1 - 4.2 8.4 11.7 1.8 9.6 0.6 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGB10993.1 - 5.1 8.0 0.0 5.1 8.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB10993.1 - 7.5 6.9 15.5 7.8 6.9 0.2 4.2 4 1 2 6 6 6 0 Tetratricopeptide repeat FMN_red PF03358.15 EGB10994.1 - 2.2e-24 86.0 0.0 2.8e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGB10994.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin-like fold Rimk_N PF18030.1 EGB10994.1 - 0.087 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 RimK PreATP-grasp domain Tyrosinase PF00264.20 EGB10995.1 - 2.3e-10 41.2 1.1 1e-05 25.9 0.3 2.4 2 1 0 2 2 2 2 Common central domain of tyrosinase PKD PF00801.20 EGB10995.1 - 0.0072 16.2 0.3 0.02 14.7 0.3 1.7 1 0 0 1 1 1 1 PKD domain RPE65 PF03055.15 EGB10996.1 - 7.8e-56 190.2 0.0 3.1e-33 115.7 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein DUF1330 PF07045.11 EGB10997.1 - 3.9e-20 72.0 0.1 4.5e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) DUF92 PF01940.16 EGB10999.1 - 3.2e-45 154.4 16.2 1.1e-44 152.7 16.2 1.7 1 1 0 1 1 1 1 Integral membrane protein DUF92 Clat_adaptor_s PF01217.20 EGB11000.1 - 1.7e-37 128.5 0.6 2.4e-37 128.0 0.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain WD40 PF00400.32 EGB11001.1 - 4.3e-41 138.1 18.2 6.5e-08 33.1 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11001.1 - 1.3e-17 63.9 0.3 0.00041 20.6 0.0 5.2 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB11001.1 - 1.6e-10 40.3 6.1 0.0056 15.4 0.1 4.9 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGB11001.1 - 2.6e-07 29.9 1.7 0.31 10.0 0.0 5.5 3 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB11001.1 - 9.9e-07 28.8 0.3 0.0032 17.4 0.0 3.9 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 EGB11001.1 - 0.002 17.7 4.7 0.64 9.6 1.1 2.7 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.6 EGB11001.1 - 0.0044 16.4 2.7 3.5 6.9 0.0 4.0 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 EGB11001.1 - 0.0087 14.6 0.7 11 4.5 0.0 3.3 1 1 3 4 4 4 1 Cytochrome D1 heme domain Hira PF07569.11 EGB11001.1 - 0.0087 15.8 0.1 2.3 7.9 0.0 3.3 2 1 1 3 3 3 1 TUP1-like enhancer of split WD40_like PF17005.5 EGB11001.1 - 0.05 12.9 0.0 0.55 9.5 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 EGB11001.1 - 1.8 9.1 11.8 8.7 7.0 0.1 5.2 4 2 1 5 5 5 0 PQQ-like domain PDZ_6 PF17820.1 EGB11002.1 - 2.7e-06 27.1 1.7 6.8e-06 25.8 1.7 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGB11002.1 - 2.9e-06 27.5 0.3 8e-06 26.1 0.3 1.8 1 0 0 1 1 1 1 PDZ domain OmpA PF00691.20 EGB11002.1 - 4.6e-06 26.9 0.0 2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 OmpA family PDZ PF00595.24 EGB11002.1 - 0.00019 21.7 0.1 0.00073 19.8 0.1 1.9 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 EGB11002.1 - 0.00022 21.3 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGB11002.1 - 0.032 14.7 0.0 6.6 7.3 0.0 2.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) AgrB PF04647.15 EGB11002.1 - 0.91 8.8 4.5 1.5 8.1 4.5 1.2 1 0 0 1 1 1 0 Accessory gene regulator B zf-RanBP PF00641.18 EGB11003.1 - 0.06 12.7 7.2 0.83 9.0 2.2 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others LRR_4 PF12799.7 EGB11004.1 - 4.8e-15 55.4 14.8 2.2e-08 34.3 0.3 3.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB11004.1 - 5.7e-12 45.5 0.4 3.4e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EGB11004.1 - 1.6e-10 40.6 8.9 2.6e-06 27.1 2.1 3.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EGB11004.1 - 0.002 18.0 4.0 8.6 6.7 0.2 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 EGB11004.1 - 0.0058 17.0 3.8 7.3 7.6 0.1 4.0 4 0 0 4 4 4 1 Leucine Rich Repeat FNIP PF05725.12 EGB11004.1 - 0.024 14.8 0.4 0.069 13.3 0.1 2.1 2 0 0 2 2 2 0 FNIP Repeat Sec20 PF03908.13 EGB11004.1 - 0.12 12.3 0.1 0.44 10.5 0.0 2.0 1 1 1 2 2 2 0 Sec20 DUF4537 PF15057.6 EGB11005.1 - 2.4e-07 30.8 0.2 0.002 18.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 EGB11005.1 - 0.0058 16.4 0.0 6.8 6.6 0.0 3.4 3 0 0 3 3 3 2 Lamin-B receptor of TUDOR domain SH3_9 PF14604.6 EGB11005.1 - 0.013 15.4 0.3 2.9 7.8 0.0 3.4 3 0 0 3 3 3 0 Variant SH3 domain adh_short PF00106.25 EGB11006.1 - 3.7e-15 55.9 6.4 3.9e-15 55.8 0.2 3.1 4 0 0 4 4 4 1 short chain dehydrogenase TTL PF03133.15 EGB11006.1 - 2.2e-13 50.0 0.0 3.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family adh_short_C2 PF13561.6 EGB11006.1 - 6e-05 22.7 3.7 0.0002 21.0 3.7 2.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB11006.1 - 0.0081 16.1 0.8 0.023 14.6 0.8 1.7 1 0 0 1 1 1 1 KR domain APG6_N PF17675.1 EGB11006.1 - 5.2 7.6 14.2 12 6.4 14.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region DSPc PF00782.20 EGB11007.1 - 4.3e-19 68.6 0.0 6e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB11007.1 - 1.2e-05 25.0 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGB11007.1 - 0.0013 18.8 0.2 0.0021 18.0 0.2 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family NAD_binding_8 PF13450.6 EGB11007.1 - 0.066 13.5 0.7 0.14 12.4 0.7 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_60s PF00428.19 EGB11007.1 - 1.8 9.2 7.5 7.9 7.1 2.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Na_H_Exchanger PF00999.21 EGB11008.1 - 3.8e-60 203.7 26.4 5.2e-60 203.3 26.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family BPA_C PF18040.1 EGB11008.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 beta porphyranase A C-terminal Myosin_head PF00063.21 EGB11009.1 - 7.2e-197 655.7 0.0 8.9e-197 655.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 EGB11009.1 - 0.001 19.4 0.0 0.0044 17.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB11009.1 - 0.002 18.5 2.2 0.0025 18.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 EGB11009.1 - 0.046 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGB11009.1 - 0.053 13.2 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 EGB11009.1 - 0.078 12.5 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TrwB_AAD_bind PF10412.9 EGB11009.1 - 0.086 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 EGB11009.1 - 0.18 11.0 0.9 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EGB11009.1 - 0.21 11.7 7.3 9.5 6.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Chloroa_b-bind PF00504.21 EGB11010.1 - 0.0013 19.2 0.0 0.0015 19.1 0.0 1.2 1 1 0 1 1 1 1 Chlorophyll A-B binding protein PHD PF00628.29 EGB11011.1 - 0.017 15.0 19.8 0.036 14.0 19.8 1.5 1 0 0 1 1 1 0 PHD-finger Zn_Tnp_IS91 PF14319.6 EGB11011.1 - 1.4 9.0 11.5 3.3 7.8 11.5 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain Ribosomal_L11_N PF03946.14 EGB11012.1 - 5.1e-20 71.1 0.2 8.6e-20 70.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGB11012.1 - 2e-17 63.4 0.2 2.1e-16 60.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain CorC_HlyC PF03471.17 EGB11012.1 - 0.018 15.0 0.0 0.05 13.6 0.0 1.7 2 0 0 2 2 2 0 Transporter associated domain Thioredoxin PF00085.20 EGB11013.1 - 2e-19 69.5 0.0 3.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DnaJ PF00226.31 EGB11013.1 - 1.7e-11 44.1 1.6 3.5e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain Transglut_core PF01841.19 EGB11013.1 - 2.5e-06 27.9 0.1 1.3e-05 25.6 0.1 2.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily Thioredoxin_2 PF13098.6 EGB11013.1 - 2.7e-05 24.6 0.0 0.00016 22.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Myb_DNA-binding PF00249.31 EGB11013.1 - 0.00063 19.9 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Thioredoxin_7 PF13899.6 EGB11013.1 - 0.069 13.3 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like Myb_DNA-bind_6 PF13921.6 EGB11013.1 - 0.16 12.2 0.3 2.2 8.6 0.6 2.4 1 1 1 2 2 2 0 Myb-like DNA-binding domain Redoxin PF08534.10 EGB11013.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Redoxin OST3_OST6 PF04756.13 EGB11013.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RNase_T PF00929.24 EGB11014.1 - 1.8e-23 83.9 0.0 2.1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease BTB PF00651.31 EGB11015.1 - 4.1e-10 39.9 0.0 5.1e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain ADK PF00406.22 EGB11016.1 - 7.7e-36 123.5 0.0 1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGB11016.1 - 8.6e-24 84.5 0.0 1.2e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB11016.1 - 9.3e-05 22.6 0.2 0.00032 20.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EGB11016.1 - 0.0013 18.5 1.9 0.55 9.9 0.0 2.1 2 0 0 2 2 2 2 Cytidylate kinase AAA_19 PF13245.6 EGB11016.1 - 0.0022 18.4 0.4 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 EGB11016.1 - 0.0034 17.3 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 NACHT PF05729.12 EGB11016.1 - 0.013 15.5 0.0 0.062 13.2 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 EGB11016.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EGB11016.1 - 0.07 12.4 0.2 0.24 10.7 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EGB11016.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGB11016.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Amidohydro_3 PF07969.11 EGB11017.1 - 2.2e-17 63.7 2.8 7.9e-10 38.8 0.1 2.6 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGB11017.1 - 5.5e-16 58.8 0.0 1.6e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family NUDIX PF00293.28 EGB11017.1 - 0.012 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Lyase_aromatic PF00221.19 EGB11018.1 - 2.4e-183 610.0 4.8 2.7e-183 609.9 4.8 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Pyr_redox_2 PF07992.14 EGB11019.1 - 9.6e-28 97.3 0.1 6.8e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EGB11019.1 - 3.1e-21 75.2 0.1 4.8e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 EGB11019.1 - 1e-09 38.8 0.3 2.8e-06 27.8 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB11019.1 - 5.5e-09 36.1 0.0 1.6e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB11019.1 - 2.3e-08 34.0 0.5 0.002 17.8 0.2 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGB11019.1 - 2.5e-07 30.4 0.0 1.2e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EGB11019.1 - 2.5e-06 26.5 0.4 2.8e-05 23.0 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGB11019.1 - 1.3e-05 24.6 0.1 0.054 12.7 0.0 3.7 2 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB11019.1 - 3.8e-05 23.1 0.1 3.8e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGB11019.1 - 6.8e-05 22.4 0.0 6.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB11019.1 - 7e-05 22.1 0.2 7e-05 22.1 0.2 2.8 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EGB11019.1 - 9.5e-05 21.7 0.4 0.00073 18.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EGB11019.1 - 0.00029 20.2 0.7 0.013 14.8 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EGB11019.1 - 0.0014 19.1 0.2 0.28 11.6 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 EGB11019.1 - 0.0021 17.2 1.8 0.065 12.3 0.3 2.7 2 1 1 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EGB11019.1 - 0.0043 17.1 0.3 0.9 9.5 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EGB11019.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EGB11019.1 - 0.023 14.6 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGB11019.1 - 0.059 12.7 0.0 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.24 EGB11019.1 - 0.08 12.7 2.0 2.5 7.9 0.1 2.9 1 1 2 3 3 3 0 DJ-1/PfpI family Lycopene_cycl PF05834.12 EGB11019.1 - 0.12 11.4 0.2 0.92 8.5 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein zf-CRD PF17979.1 EGB11019.1 - 0.13 12.4 0.4 0.22 11.6 0.4 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Trp_halogenase PF04820.14 EGB11019.1 - 0.25 10.2 0.0 0.84 8.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase tRNA-synt_1e PF01406.19 EGB11020.1 - 1.5e-97 326.6 0.0 1.7e-97 326.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGB11020.1 - 3.5e-08 32.6 0.0 0.00055 18.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGB11020.1 - 0.039 12.2 0.0 0.76 7.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) U-box PF04564.15 EGB11021.1 - 9.8e-16 57.7 0.0 1.3e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB11021.1 - 5.9e-06 26.0 0.0 9.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGB11021.1 - 0.0029 17.6 0.0 0.0056 16.7 0.0 1.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGB11021.1 - 0.0047 17.1 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGB11021.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M48 PF01435.18 EGB11022.1 - 4.2e-23 82.1 0.0 6.9e-22 78.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M78 PF06114.13 EGB11022.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 IrrE N-terminal-like domain Radical_SAM PF04055.21 EGB11023.1 - 2.4e-23 83.3 0.0 4.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 EGB11023.1 - 8e-20 71.0 0.1 1.8e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 Wyosine base formation Histone PF00125.24 EGB11025.1 - 5.3e-19 68.9 0.4 6.3e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB11025.1 - 1.9e-05 24.8 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB11025.1 - 0.0038 17.7 0.0 0.0059 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB11025.1 - 0.053 13.6 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein CENP-T_C PF15511.6 EGB11026.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB11026.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB11026.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB11026.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB11026.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB11026.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB11026.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGB11026.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EGB11027.1 - 5.4e-19 68.8 0.4 6.5e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB11027.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB11027.1 - 0.0039 17.7 0.0 0.0061 17.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB11027.1 - 0.054 13.5 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein zf-dskA_traR PF01258.17 EGB11028.1 - 0.0002 21.2 7.3 0.00035 20.4 3.7 2.7 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger PHD PF00628.29 EGB11028.1 - 0.00056 19.8 6.9 0.001 18.9 6.9 1.5 1 0 0 1 1 1 1 PHD-finger TUDOR_5 PF18359.1 EGB11028.1 - 0.0099 15.6 4.6 0.023 14.4 4.6 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 EGB11028.1 - 0.031 14.1 0.4 0.063 13.1 0.4 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain NHase_beta PF02211.15 EGB11028.1 - 0.098 12.7 0.1 0.098 12.7 0.1 1.8 2 0 0 2 2 2 0 Nitrile hydratase beta subunit HBM PF16591.5 EGB11029.1 - 0.02 14.4 0.3 0.035 13.5 0.3 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain NADH_B2 PF14813.6 EGB11029.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 EGF_2 PF07974.13 EGB11030.1 - 3.6e-13 49.6 42.1 5.8e-06 26.6 8.7 4.2 4 0 0 4 4 4 4 EGF-like domain S_locus_glycop PF00954.20 EGB11030.1 - 0.00019 21.9 0.5 0.00019 21.9 0.5 2.9 3 0 0 3 3 3 1 S-locus glycoprotein domain EGF PF00008.27 EGB11030.1 - 0.0002 21.6 36.7 0.29 11.5 0.4 4.6 4 1 1 5 5 5 4 EGF-like domain Laminin_EGF PF00053.24 EGB11030.1 - 0.041 14.0 7.8 0.041 14.0 7.8 3.4 2 1 1 3 3 3 0 Laminin EGF domain Ras PF00071.22 EGB11031.1 - 6e-53 178.8 0.0 7.1e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB11031.1 - 5.1e-31 107.4 0.0 7.6e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB11031.1 - 8.6e-13 48.1 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB11031.1 - 5.7e-06 26.4 0.0 1.8e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGB11031.1 - 0.00017 21.0 0.0 0.00021 20.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGB11031.1 - 0.00066 19.3 0.0 0.0027 17.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 EGB11031.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein TetR_C_30 PF17939.1 EGB11031.1 - 0.093 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RsgA_GTPase PF03193.16 EGB11031.1 - 0.14 12.0 0.0 18 5.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase WD40 PF00400.32 EGB11032.1 - 4.3e-58 191.9 18.0 3.1e-09 37.3 0.0 9.4 8 2 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11032.1 - 5.8e-20 71.4 0.3 7.2e-05 23.0 0.0 6.3 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EGB11032.1 - 5.3e-09 36.5 0.0 8.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EGB11032.1 - 0.01 14.5 4.7 1.2 7.7 0.1 3.8 2 2 1 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGB11032.1 - 0.014 14.4 1.5 18 4.2 0.0 4.2 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGB11032.1 - 0.22 10.3 0.0 0.99 8.1 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like Aa_trans PF01490.18 EGB11033.1 - 1.3e-30 106.4 6.5 1.8e-30 106.0 6.5 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pyrophosphatase PF00719.19 EGB11034.1 - 4.1e-47 159.9 0.1 7.5e-47 159.1 0.0 1.4 2 0 0 2 2 2 1 Inorganic pyrophosphatase SET PF00856.28 EGB11035.1 - 1.2e-19 71.4 0.0 8.2e-19 68.6 0.0 1.9 1 1 0 1 1 1 1 SET domain Adeno_Penton_B PF01686.17 EGB11035.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein Myosin_head PF00063.21 EGB11036.1 - 3.7e-179 597.2 0.0 5.2e-179 596.7 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB11036.1 - 0.0021 18.4 0.1 0.0051 17.2 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGB11036.1 - 0.051 13.9 0.5 0.24 11.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain LRR_9 PF14580.6 EGB11037.1 - 6.8e-05 22.4 0.0 7.9e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGB11037.1 - 0.00097 19.5 0.0 0.0057 17.1 0.0 2.1 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) Ribosomal_L7Ae PF01248.26 EGB11038.1 - 1.3e-23 82.5 3.8 1.8e-23 82.1 1.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Annexin PF00191.20 EGB11039.1 - 6.4e-53 176.7 0.2 7.4e-15 54.8 0.1 4.1 4 0 0 4 4 4 4 Annexin DUF3161 PF11362.8 EGB11039.1 - 0.16 11.9 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) VirB8 PF04335.13 EGB11040.1 - 2.5 7.9 5.9 0.6 9.9 1.0 2.4 3 0 0 3 3 3 0 VirB8 protein Pkinase PF00069.25 EGB11041.1 - 2.2e-58 197.7 0.0 2.5e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11041.1 - 1.7e-29 102.9 0.0 2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGB11041.1 - 0.0013 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGB11041.1 - 0.038 12.8 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGB11041.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like IncF PF17626.2 EGB11042.1 - 1.9 8.9 7.1 1.9 8.9 5.0 2.1 2 1 0 2 2 2 0 Inclusion membrane protein F Cu-oxidase_2 PF07731.14 EGB11043.1 - 1.6e-21 76.5 1.8 9.3e-20 70.8 0.6 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGB11043.1 - 2.6e-13 50.0 0.4 1.6e-11 44.3 0.4 2.6 1 1 0 1 1 1 1 Multicopper oxidase Cyt-b5 PF00173.28 EGB11044.1 - 3e-17 62.5 0.0 3.9e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MCD PF05292.11 EGB11045.1 - 2.2e-66 224.1 0.0 4.5e-66 223.0 0.0 1.5 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain SDH_C PF18317.1 EGB11045.1 - 0.73 9.7 5.6 15 5.5 0.1 3.2 3 0 0 3 3 3 0 Shikimate 5'-dehydrogenase C-terminal domain tRNA-synt_1b PF00579.25 EGB11046.1 - 1.7e-16 60.4 0.0 9e-16 58.0 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) CRAL_TRIO PF00650.20 EGB11047.1 - 6.2e-22 78.0 0.0 7.8e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGB11047.1 - 1.1e-06 28.8 0.0 1.5e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pro_isomerase PF00160.21 EGB11048.1 - 1.1e-45 155.7 0.5 1.2e-45 155.6 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UNC-93 PF05978.16 EGB11049.1 - 4.2e-08 33.1 7.7 4.2e-08 33.1 7.7 2.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 PrmA PF06325.13 EGB11051.1 - 2.4e-09 37.0 0.0 3.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGB11051.1 - 1.4e-08 35.3 0.2 1.7e-06 28.6 0.1 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB11051.1 - 1.9e-06 28.4 0.4 0.00029 21.4 0.1 3.2 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EGB11051.1 - 2.3e-05 24.2 0.1 3.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGB11051.1 - 0.00026 20.9 0.0 0.00045 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EGB11051.1 - 0.0003 19.9 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EGB11051.1 - 0.0005 19.7 0.1 0.00088 18.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 EGB11051.1 - 0.0026 17.6 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 EGB11051.1 - 0.0032 17.2 0.1 0.0055 16.4 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EGB11051.1 - 0.0035 17.2 0.1 0.006 16.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGB11051.1 - 0.0035 17.0 0.0 0.012 15.3 0.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 EGB11051.1 - 0.007 17.1 0.0 0.046 14.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGB11051.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGB11051.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 EGB11051.1 - 0.037 15.0 0.2 0.13 13.3 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain ADH_zinc_N PF00107.26 EGB11051.1 - 0.11 12.5 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase tRNA_U5-meth_tr PF05958.11 EGB11051.1 - 0.2 10.6 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RCC1 PF00415.18 EGB11052.1 - 3.8e-47 158.7 7.8 7.2e-13 49.0 0.0 5.1 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB11052.1 - 8.7e-15 54.1 16.7 1.2e-05 25.0 0.4 5.0 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat DUF778 PF05608.12 EGB11055.1 - 2.1e-15 57.6 0.6 2.8e-07 31.1 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) TPR_12 PF13424.6 EGB11057.1 - 6e-08 32.9 30.7 2.4e-05 24.5 2.1 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11057.1 - 9.9e-08 31.5 3.7 0.093 12.6 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11057.1 - 0.0069 16.5 11.2 11 6.5 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11057.1 - 0.06 13.2 3.2 4.9 7.2 0.2 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11057.1 - 0.083 13.0 0.3 0.083 13.0 0.3 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Cupin_8 PF13621.6 EGB11058.1 - 7.1e-28 98.0 0.1 1.2e-27 97.3 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB11058.1 - 2e-05 24.2 0.1 4.6e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein Sulfatase PF00884.23 EGB11059.1 - 4.3e-53 180.7 0.0 1.2e-25 90.6 0.0 2.2 2 0 0 2 2 2 2 Sulfatase ANF_receptor PF01094.28 EGB11059.1 - 1.1e-26 93.8 0.1 2.3e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 EGB11059.1 - 1e-14 55.0 25.7 2.1e-14 54.0 25.7 1.4 1 0 0 1 1 1 1 Periplasmic binding protein dCache_1 PF02743.18 EGB11059.1 - 1.3e-13 51.3 0.2 2.5e-12 47.1 0.3 2.2 1 1 0 1 1 1 1 Cache domain Ephrin_rec_like PF07699.13 EGB11059.1 - 1.4e-06 28.0 30.2 0.00022 20.9 9.5 4.2 2 1 2 4 4 4 3 Putative ephrin-receptor like Sulfatase_C PF14707.6 EGB11059.1 - 0.13 13.0 4.1 2.3 9.0 4.1 2.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Myosin_head PF00063.21 EGB11060.1 - 3.6e-165 550.9 0.0 4.8e-165 550.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB11060.1 - 0.00079 19.8 0.5 0.00079 19.8 0.5 3.3 2 2 0 2 2 2 1 AAA ATPase domain Filament PF00038.21 EGB11060.1 - 0.0033 17.1 3.8 0.12 11.9 0.6 2.2 2 0 0 2 2 2 2 Intermediate filament protein AAA_22 PF13401.6 EGB11060.1 - 0.11 12.7 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain ZapB PF06005.12 EGB11060.1 - 0.19 12.2 3.0 1.6 9.2 0.1 2.8 2 1 1 3 3 3 0 Cell division protein ZapB ATG16 PF08614.11 EGB11060.1 - 0.24 11.6 8.0 0.47 10.6 8.0 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 EGB11060.1 - 0.26 12.0 0.4 28 5.4 0.1 2.9 2 1 1 3 3 3 0 Initiation control protein YabA TerD PF02342.18 EGB11061.1 - 2.9e-55 186.6 0.0 2.4e-28 98.9 0.0 2.2 2 0 0 2 2 2 2 TerD domain Pro-kuma_activ PF09286.11 EGB11061.1 - 8.5e-22 78.0 0.0 2.2e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain C2 PF00168.30 EGB11061.1 - 6.7e-18 64.9 0.0 1.5e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain Peptidase_S8 PF00082.22 EGB11061.1 - 0.0025 17.1 3.9 0.0025 17.1 3.9 1.7 2 0 0 2 2 2 1 Subtilase family YGGT PF02325.17 EGB11062.1 - 0.065 13.7 0.3 0.14 12.6 0.3 1.6 1 0 0 1 1 1 0 YGGT family Pkinase PF00069.25 EGB11063.1 - 4.2e-49 167.3 0.0 4.7e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11063.1 - 1.8e-23 83.1 0.0 2.4e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB11063.1 - 0.046 13.1 0.0 0.071 12.5 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB11063.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase UPF0126 PF03458.13 EGB11064.1 - 1.3e-40 137.1 18.8 1.3e-22 79.5 5.4 2.7 3 0 0 3 3 3 2 UPF0126 domain GTP_EFTU PF00009.27 EGB11065.1 - 4.5e-42 143.8 0.0 5.8e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGB11065.1 - 5.8e-21 74.9 0.0 2.5e-20 72.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGB11065.1 - 1.1e-08 35.3 0.2 2.8e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGB11065.1 - 0.00088 19.3 0.0 0.0041 17.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Abhydrolase_2 PF02230.16 EGB11067.1 - 3.4e-07 30.3 0.0 6.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Stc1 PF12898.7 EGB11067.1 - 0.13 12.8 0.7 0.33 11.5 0.7 1.7 1 0 0 1 1 1 0 Stc1 domain Peptidase_S9 PF00326.21 EGB11067.1 - 0.17 11.3 0.2 7.8 5.9 0.0 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase family TPR_12 PF13424.6 EGB11067.1 - 0.39 11.0 7.4 6.8 7.1 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M16 PF00675.20 EGB11068.1 - 2.3e-10 40.6 0.0 3.4e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 EGB11068.1 - 0.011 15.1 0.0 0.034 13.4 0.1 1.7 2 0 0 2 2 2 0 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EGB11068.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain WD40_4 PF16300.5 EGB11069.1 - 5.1e-21 74.3 0.2 9.7e-21 73.4 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 EGB11069.1 - 3e-19 68.7 0.1 5.3e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 EGB11069.1 - 4.5e-11 43.1 4.1 0.0014 19.4 0.1 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11069.1 - 4.1e-05 23.8 0.0 0.017 15.4 0.0 3.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FlhE PF06366.13 EGB11069.1 - 0.13 12.2 0.1 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein FlhE zf-RING_2 PF13639.6 EGB11070.1 - 1.1e-12 48.1 5.4 2.1e-12 47.2 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGB11070.1 - 1.2e-07 31.3 1.9 2.8e-07 30.1 1.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGB11070.1 - 2.6e-07 30.3 5.4 4.6e-07 29.6 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB11070.1 - 7.1e-07 29.4 7.7 1.4e-05 25.3 7.7 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGB11070.1 - 1.7e-06 27.9 2.7 2.8e-06 27.2 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGB11070.1 - 2.4e-06 27.3 3.5 4.3e-06 26.5 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB11070.1 - 5.6e-06 26.1 4.2 2.1e-05 24.3 4.2 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGB11070.1 - 1.2e-05 25.2 0.6 2.1e-05 24.4 0.2 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGB11070.1 - 0.00037 20.3 3.7 0.00037 20.3 3.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGB11070.1 - 0.0049 16.5 2.9 0.0049 16.5 2.9 2.1 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 EGB11070.1 - 0.018 15.0 1.4 0.018 15.0 1.4 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 RINGv PF12906.7 EGB11070.1 - 0.042 14.0 2.6 0.11 12.7 2.6 1.7 1 1 0 1 1 1 0 RING-variant domain Cwf_Cwc_15 PF04889.12 EGB11070.1 - 0.08 12.7 12.9 0.13 12.0 12.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGB11070.1 - 0.084 11.0 9.9 0.1 10.7 9.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi UBZ_FAAP20 PF15750.5 EGB11070.1 - 0.088 12.8 2.6 0.32 11.0 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Vps39_2 PF10367.9 EGB11070.1 - 0.1 13.1 1.3 0.76 10.3 0.4 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-ANAPC11 PF12861.7 EGB11070.1 - 0.11 12.6 5.0 0.87 9.7 5.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GCIP PF13324.6 EGB11070.1 - 0.11 12.0 1.9 0.15 11.7 1.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF3245 PF11595.8 EGB11070.1 - 0.33 11.4 4.8 0.64 10.5 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PPP4R2 PF09184.11 EGB11070.1 - 0.34 10.5 6.1 0.45 10.1 6.1 1.2 1 0 0 1 1 1 0 PPP4R2 DUF3295 PF11702.8 EGB11070.1 - 0.47 9.7 6.3 0.64 9.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nucleo_P87 PF07267.11 EGB11070.1 - 0.71 8.7 5.9 0.85 8.4 5.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VID27_N PF17748.1 EGB11070.1 - 0.8 9.5 8.7 0.029 14.2 3.1 1.5 2 0 0 2 2 1 0 VID27 N-terminal region Nop14 PF04147.12 EGB11070.1 - 1.3 7.1 10.3 1.6 6.9 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGB11070.1 - 2 7.7 10.5 2.6 7.3 10.5 1.1 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.10 EGB11070.1 - 4.3 7.8 20.1 11 6.5 20.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Histone PF00125.24 EGB11071.1 - 3.9e-16 59.6 0.5 4.8e-16 59.3 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB11071.1 - 0.0038 17.5 0.1 0.0098 16.2 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB11071.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A BBE PF08031.12 EGB11072.1 - 5.1e-10 39.3 0.0 9.1e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like AAA PF00004.29 EGB11073.1 - 5.7e-21 75.3 0.0 6.4e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 EGB11074.1 - 6.2e-29 101.2 0.3 6.1e-24 84.9 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M41 Mito_carr PF00153.27 EGB11076.1 - 7e-17 61.1 8.2 2.2e-06 27.5 0.3 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein HD_4 PF13328.6 EGB11077.1 - 5.3e-48 162.7 0.4 1.3e-47 161.4 0.4 1.7 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 EGB11077.1 - 4.1e-30 104.5 0.0 8.2e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 EGB11077.1 - 1.2e-07 31.6 0.0 3.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain HD PF01966.22 EGB11077.1 - 1.5e-07 31.7 0.7 4.1e-07 30.3 0.2 2.0 2 0 0 2 2 2 1 HD domain ThiS PF02597.20 EGB11077.1 - 0.00084 19.9 0.1 0.0034 18.0 0.0 2.1 2 0 0 2 2 2 1 ThiS family Ntox4 PF15541.6 EGB11077.1 - 0.025 14.9 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial toxin 4 DNA_pol_B_thumb PF14791.6 EGB11078.1 - 2.5e-11 43.6 1.0 3.3e-05 24.0 0.1 2.5 2 0 0 2 2 2 2 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EGB11078.1 - 0.00074 19.7 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm Clat_adaptor_s PF01217.20 EGB11079.1 - 6.8e-43 146.0 1.7 8.3e-43 145.7 1.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HOCHOB PF17943.1 EGB11079.1 - 0.11 13.2 0.7 4.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox zf-CCCH PF00642.24 EGB11081.1 - 9.8e-09 34.9 3.0 9.8e-09 34.9 3.0 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 EGB11081.1 - 2.1e-08 33.9 10.6 3.8e-08 33.0 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB11081.1 - 3.4e-08 33.2 10.7 5.9e-08 32.5 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB11081.1 - 1.2e-07 31.5 10.9 2.4e-07 30.6 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGB11081.1 - 1.2e-07 31.4 7.5 2.6e-07 30.4 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB11081.1 - 7.1e-07 29.2 4.3 7.1e-07 29.2 4.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGB11081.1 - 7.5e-06 26.2 9.9 1.5e-05 25.2 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGB11081.1 - 2.4e-05 24.1 7.2 4.4e-05 23.2 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGB11081.1 - 3.6e-05 23.8 9.3 8.4e-05 22.7 9.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf_CCCH_4 PF18345.1 EGB11081.1 - 0.00013 21.9 10.6 0.00017 21.5 5.5 2.9 3 0 0 3 3 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGB11081.1 - 0.0036 17.0 3.9 0.0036 17.0 3.9 3.4 3 0 0 3 3 3 1 CCCH-type zinc finger zf-Nse PF11789.8 EGB11081.1 - 0.005 16.6 3.5 0.009 15.8 3.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 EGB11081.1 - 0.021 14.9 5.0 0.021 14.9 5.0 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-P11 PF03854.14 EGB11081.1 - 0.043 13.5 3.8 0.095 12.4 3.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger DUF3624 PF12292.8 EGB11081.1 - 0.059 13.8 0.4 0.098 13.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) FYVE_2 PF02318.16 EGB11081.1 - 0.082 13.1 1.3 0.16 12.2 1.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-rbx1 PF12678.7 EGB11081.1 - 0.082 13.2 6.7 0.21 11.9 6.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain S19 PF06756.11 EGB11081.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S19 C-terminal zf-RING_6 PF14835.6 EGB11081.1 - 0.37 10.7 3.3 0.73 9.7 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCCH_2 PF14608.6 EGB11081.1 - 2.6 8.6 9.0 0.28 11.7 3.9 2.2 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger zf-RING_4 PF14570.6 EGB11081.1 - 2.9 7.8 11.0 16 5.4 11.1 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Patatin PF01734.22 EGB11082.1 - 4.2e-14 53.2 0.1 4.5e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase TetR_C_6 PF13977.6 EGB11082.1 - 0.081 13.1 0.2 0.096 12.9 0.2 1.0 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal Alpha_kinase PF02816.18 EGB11083.1 - 8.1e-19 68.4 0.0 9.5e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Glutaredoxin PF00462.24 EGB11084.1 - 3.7e-34 116.7 0.0 2.5e-16 59.6 0.0 3.7 4 0 0 4 4 4 2 Glutaredoxin Thioredoxin PF00085.20 EGB11084.1 - 3.1e-10 40.0 0.1 2e-09 37.4 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin HyaE PF07449.11 EGB11084.1 - 3.4e-05 23.8 0.2 0.0011 18.8 0.0 3.2 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 EGB11084.1 - 0.0021 18.3 0.0 1.6 9.1 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB11084.1 - 0.008 16.6 0.0 0.06 13.8 0.0 2.5 2 1 1 3 3 3 1 Thioredoxin-like domain SH3BGR PF04908.15 EGB11084.1 - 0.014 15.5 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Thioredoxin_7 PF13899.6 EGB11084.1 - 0.032 14.4 0.2 0.2 11.8 0.0 2.4 3 0 0 3 3 3 0 Thioredoxin-like GST_N_3 PF13417.6 EGB11084.1 - 0.074 13.5 0.0 6 7.3 0.0 3.0 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain KaiB PF07689.12 EGB11084.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiB domain Methyltransf_28 PF02636.17 EGB11085.1 - 4.4e-60 203.5 0.0 5.4e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Nucleotid_trans PF03407.16 EGB11086.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF4054 PF13262.6 EGB11086.1 - 0.63 10.1 4.1 11 6.2 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Gln_amidase PF15644.6 EGB11086.1 - 5 8.2 5.1 17 6.5 0.2 3.4 3 1 0 3 3 3 0 Papain fold toxin 1, glutamine deamidase UQ_con PF00179.26 EGB11087.1 - 7.4e-32 109.9 0.0 8.5e-32 109.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGB11087.1 - 0.18 12.1 0.1 0.18 12.1 0.1 1.3 1 1 0 1 1 1 0 RWD domain SPOUT_MTase PF02590.17 EGB11088.1 - 1.1e-30 106.6 0.0 5.9e-30 104.3 0.0 1.8 1 1 0 1 1 1 1 Predicted SPOUT methyltransferase Ank_2 PF12796.7 EGB11089.1 - 1.6e-37 127.9 2.2 3.7e-12 46.6 0.0 4.2 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB11089.1 - 4.3e-32 110.1 5.6 2.4e-07 31.2 0.1 7.0 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EGB11089.1 - 1.6e-28 97.9 17.6 0.00026 21.3 0.0 9.1 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EGB11089.1 - 2.2e-26 91.6 12.3 2.3e-07 31.0 0.3 6.1 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11089.1 - 2e-23 79.9 10.7 0.0029 18.0 0.2 8.6 9 0 0 9 9 9 5 Ankyrin repeat Sec31 PF11549.8 EGB11089.1 - 0.018 14.9 0.0 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein transport protein SEC31 PAN_4 PF14295.6 EGB11090.1 - 0.00029 20.7 1.5 0.00088 19.1 1.5 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EGB11090.1 - 0.012 15.5 0.4 0.049 13.6 0.1 2.0 2 0 0 2 2 2 0 PAN domain PreAtp-grasp PF18604.1 EGB11090.1 - 0.18 11.4 1.4 6.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Pre ATP-grasp domain EamA PF00892.20 EGB11091.1 - 1.9e-05 24.8 2.2 1.9e-05 24.8 2.2 3.0 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 EGB11091.1 - 0.00054 19.4 1.4 0.004 16.6 0.1 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family PUNUT PF16913.5 EGB11091.1 - 0.014 14.6 0.2 0.027 13.7 0.2 1.4 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport Castor_Poll_mid PF06241.12 EGB11092.1 - 5.6e-32 109.8 0.0 3.3e-30 104.1 0.0 2.6 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 EGB11092.1 - 0.00013 21.7 0.0 0.00052 19.8 0.0 2.1 2 0 0 2 2 2 1 TrkA-C domain DUF3159 PF11361.8 EGB11092.1 - 0.001 18.9 2.7 0.0016 18.2 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3159) Pkinase PF00069.25 EGB11093.1 - 5.2e-30 104.7 0.0 5.7e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11093.1 - 1.7e-15 57.0 0.0 1.9e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase COesterase PF00135.28 EGB11094.1 - 9e-63 212.9 2.2 1e-62 212.7 2.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGB11094.1 - 0.00013 21.5 0.6 0.00019 21.0 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGB11094.1 - 0.00042 20.2 2.9 0.00047 20.1 0.5 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 EGB11094.1 - 0.13 11.9 2.1 0.21 11.2 2.1 1.5 1 1 0 1 1 1 0 Putative esterase DUF4200 PF13863.6 EGB11095.1 - 8.1e-35 119.8 24.2 8.1e-35 119.8 24.2 6.2 6 1 0 6 6 6 1 Domain of unknown function (DUF4200) OmpH PF03938.14 EGB11095.1 - 0.0044 17.4 9.7 0.0044 17.4 9.7 5.2 4 1 1 5 5 5 1 Outer membrane protein (OmpH-like) Ribosomal_S6 PF01250.17 EGB11095.1 - 0.013 15.7 3.9 0.018 15.3 1.6 2.5 2 0 0 2 2 2 0 Ribosomal protein S6 YvrJ PF12841.7 EGB11095.1 - 0.034 13.7 0.6 0.14 11.7 0.6 2.2 1 0 0 1 1 1 0 YvrJ protein family SIR2 PF02146.17 EGB11095.1 - 0.047 13.6 9.5 0.13 12.2 0.2 2.9 2 1 1 3 3 3 0 Sir2 family WD40 PF00400.32 EGB11096.1 - 6.2e-05 23.7 1.7 0.016 16.0 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat IQ PF00612.27 EGB11098.1 - 0.014 15.1 21.6 0.014 15.1 0.5 4.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif Glyco_trans_2_3 PF13632.6 EGB11098.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF3246 PF11596.8 EGB11098.1 - 0.21 11.0 14.5 0.26 10.7 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PfkB PF00294.24 EGB11099.1 - 1e-39 136.6 3.5 2.2e-39 135.6 3.5 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase p450 PF00067.22 EGB11100.1 - 6.3e-43 147.2 0.0 7.9e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Yip1 PF04893.17 EGB11101.1 - 4.9e-16 58.9 18.2 1e-15 57.9 18.2 1.5 1 1 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 EGB11101.1 - 4.9 5.3 10.0 6 5.0 10.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ion_trans PF00520.31 EGB11102.1 - 5.8e-25 87.9 2.6 1.2e-23 83.6 2.7 2.1 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB11102.1 - 7e-14 51.6 2.0 1.5e-13 50.5 2.0 1.6 1 0 0 1 1 1 1 Ion channel EF-hand_1 PF00036.32 EGB11102.1 - 5.3e-11 41.2 0.5 0.00019 20.8 0.0 2.8 2 0 0 2 2 2 2 EF hand cNMP_binding PF00027.29 EGB11102.1 - 4.4e-10 39.5 0.0 9.2e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EF-hand_6 PF13405.6 EGB11102.1 - 5.7e-10 38.3 0.6 0.00039 20.1 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGB11102.1 - 5.3e-08 33.2 0.6 1.5e-07 31.7 0.6 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB11102.1 - 2.8e-07 30.3 1.2 4.6e-07 29.6 0.5 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB11102.1 - 6.4e-06 25.4 2.6 0.00066 19.1 0.2 2.5 2 0 0 2 2 2 2 EF hand Spc24 PF08286.11 EGB11103.1 - 1.9 8.8 8.3 0.26 11.5 3.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PQQ_3 PF13570.6 EGB11103.1 - 5.1 7.7 5.3 3.3 8.3 0.6 2.8 2 1 0 2 2 2 0 PQQ-like domain ADIP PF11559.8 EGB11103.1 - 7.2 6.7 17.2 0.46 10.6 9.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.25 EGB11104.1 - 7.1e-62 209.2 0.0 8e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11104.1 - 5.4e-47 160.2 0.0 6.6e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB11104.1 - 4.4e-05 23.5 0.3 0.0002 21.4 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB11104.1 - 0.006 15.4 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB11104.1 - 0.054 12.9 0.0 0.16 11.3 0.0 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family COesterase PF00135.28 EGB11105.1 - 1.7e-51 175.7 0.0 2.2e-50 172.0 0.0 2.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGB11105.1 - 5.9e-08 32.8 1.3 2.2e-07 31.0 1.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold ABC_tran PF00005.27 EGB11106.1 - 5.7e-46 156.4 0.0 2.1e-21 76.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB11106.1 - 2.9e-16 60.2 5.6 0.00048 20.0 1.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB11106.1 - 1.7e-07 30.9 0.3 0.0021 17.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB11106.1 - 4.1e-07 30.7 0.1 0.0018 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGB11106.1 - 7.1e-07 28.9 0.1 0.22 10.9 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EGB11106.1 - 1.4e-05 25.4 5.4 0.023 15.0 0.1 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EGB11106.1 - 1.8e-05 24.8 0.0 0.014 15.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EGB11106.1 - 3.3e-05 23.8 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGB11106.1 - 3.4e-05 23.8 0.2 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 NACHT domain RsgA_GTPase PF03193.16 EGB11106.1 - 0.00016 21.6 0.0 0.067 13.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGB11106.1 - 0.00033 20.9 0.1 0.78 10.0 0.1 2.8 2 1 0 2 2 2 2 AAA domain MeaB PF03308.16 EGB11106.1 - 0.0019 17.3 0.7 0.086 11.8 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGB11106.1 - 0.0039 17.8 1.0 2.9 8.4 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EGB11106.1 - 0.0049 17.0 2.5 1.3 9.2 0.1 2.9 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.6 EGB11106.1 - 0.012 15.8 0.2 3.8 7.8 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EGB11106.1 - 0.014 15.8 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF2813 PF11398.8 EGB11106.1 - 0.016 14.5 0.1 0.41 9.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) Dynamin_N PF00350.23 EGB11106.1 - 0.029 14.5 0.1 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 EGB11106.1 - 0.034 14.5 13.0 0.2 12.1 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.13 EGB11106.1 - 0.036 13.2 0.3 3.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGB11106.1 - 0.046 13.7 0.9 5.3 7.0 0.1 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EGB11106.1 - 0.061 13.4 0.1 3.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 EGB11106.1 - 0.08 12.3 0.1 2.7 7.3 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGB11106.1 - 0.12 12.0 0.0 7.7 6.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB11106.1 - 0.17 11.2 5.9 0.51 9.7 0.1 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family Sulfatase PF00884.23 EGB11107.1 - 1.7e-39 136.1 0.1 2.1e-39 135.7 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB11107.1 - 0.0062 16.2 0.1 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase ABC_membrane PF00664.23 EGB11108.1 - 7.6e-60 202.9 8.0 3.2e-59 200.8 8.0 1.8 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGB11108.1 - 3e-25 89.3 0.0 5.1e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ACR_tran PF00873.19 EGB11108.1 - 0.0075 14.0 4.0 0.012 13.4 4.0 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family AAA_28 PF13521.6 EGB11108.1 - 0.0093 16.2 0.5 0.14 12.4 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB11108.1 - 0.053 13.9 2.6 0.057 13.8 0.4 2.2 2 2 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EGB11108.1 - 0.099 13.1 0.1 3.2 8.2 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UCR_6-4kD PF08997.10 EGB11108.1 - 0.38 10.7 4.0 5.8 6.9 0.1 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein SbcCD_C PF13558.6 EGB11108.1 - 0.65 10.3 4.6 1.2 9.4 0.5 3.5 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit EF-hand_1 PF00036.32 EGB11109.1 - 1.4e-07 30.6 0.1 0.54 9.9 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB11109.1 - 2.2e-06 27.1 0.2 0.29 11.2 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGB11109.1 - 3.3e-06 27.5 0.0 0.00027 21.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB11109.1 - 0.019 14.5 0.2 0.29 10.7 0.0 2.8 3 0 0 3 3 3 0 EF hand FAM176 PF14851.6 EGB11109.1 - 0.1 12.2 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 FAM176 family POX PF07526.11 EGB11109.1 - 0.21 12.2 2.0 0.45 11.1 2.0 1.5 1 0 0 1 1 1 0 Associated with HOX EF-hand_4 PF12763.7 EGB11109.1 - 0.24 11.4 0.1 0.77 9.7 0.1 1.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand HOASN PF14515.6 EGB11109.1 - 5.9 7.3 8.1 0.56 10.6 1.7 2.6 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices Cupin_2 PF07883.11 EGB11110.1 - 3.3e-07 29.9 0.7 0.018 14.7 0.1 2.7 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 EGB11110.1 - 0.0062 16.2 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.19 EGB11110.1 - 0.031 14.2 0.2 0.73 9.7 0.0 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain FH2 PF02181.23 EGB11111.1 - 1.7e-26 93.2 0.0 2.2e-25 89.6 0.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain DUF4363 PF14276.6 EGB11111.1 - 0.27 11.4 2.0 1 9.5 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Apolipoprotein PF01442.18 EGB11111.1 - 6.5 6.6 39.4 0.044 13.7 15.4 4.2 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain DUF4363 PF14276.6 EGB11112.1 - 0.3 11.2 2.2 0.75 9.9 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Apolipoprotein PF01442.18 EGB11112.1 - 0.49 10.2 29.8 0.032 14.1 15.4 3.2 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain NOG1_N PF17835.1 EGB11113.1 - 1.2e-48 165.1 0.1 3e-48 163.8 0.1 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EGB11113.1 - 4.9e-25 87.1 0.2 9.1e-25 86.2 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EGB11113.1 - 8e-23 80.2 0.1 1.5e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EGB11113.1 - 2.7e-17 62.9 0.0 5.5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB11113.1 - 8.6e-09 35.1 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EGB11113.1 - 0.00068 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EGB11113.1 - 0.045 13.8 0.7 3.2 7.8 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Cep57_CLD PF14073.6 EGB11114.1 - 4.1e-06 26.9 22.8 6.2e-06 26.4 22.8 1.3 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 ADH_zinc_N PF00107.26 EGB11115.1 - 4.2e-24 85.0 0.2 7.4e-24 84.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB11115.1 - 9.6e-20 70.5 1.2 1.8e-19 69.6 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EGB11115.1 - 0.0013 18.1 3.5 0.013 14.8 0.5 2.2 1 1 1 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EGB11115.1 - 0.056 13.7 0.2 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EGB11115.1 - 0.1 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAS_4 PF08448.10 EGB11115.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF3619 PF12279.8 EGB11115.1 - 0.18 12.1 0.5 0.91 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Exo_endo_phos PF03372.23 EGB11116.1 - 2.4e-10 40.3 0.6 5.1e-10 39.3 0.6 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGB11116.1 - 0.0034 17.2 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase zf-RING_2 PF13639.6 EGB11117.1 - 4.9e-09 36.4 3.9 4.9e-09 36.4 3.9 2.5 2 1 2 4 4 3 1 Ring finger domain PHD PF00628.29 EGB11117.1 - 6.7e-05 22.7 1.2 6.7e-05 22.7 1.2 2.7 2 1 0 2 2 2 1 PHD-finger zf-RING_11 PF17123.5 EGB11117.1 - 0.00016 21.3 0.2 0.00016 21.3 0.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EGB11117.1 - 0.0019 18.5 11.5 0.0032 17.7 8.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGB11117.1 - 0.0036 17.1 5.5 0.0036 17.1 5.5 2.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB11117.1 - 0.0036 17.2 1.8 0.0036 17.2 1.8 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB11117.1 - 0.024 14.7 3.7 0.026 14.6 0.3 2.7 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EGB11117.1 - 0.03 14.2 1.5 0.03 14.2 1.5 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGB11117.1 - 0.036 14.2 4.6 0.036 14.2 4.6 2.3 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_3 PF13920.6 EGB11117.1 - 0.67 9.9 7.4 0.46 10.4 2.4 2.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGB11117.1 - 1.3 9.3 7.2 1.3 9.3 4.1 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EGB11117.1 - 6.1 6.7 9.4 0.75 9.6 4.8 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Myotub-related PF06602.14 EGB11118.1 - 4.3e-100 335.1 0.0 4.9e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGB11118.1 - 0.0022 18.0 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGB11118.1 - 0.0033 17.0 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ank_3 PF13606.6 EGB11119.1 - 3.4e-15 54.6 2.9 0.00072 19.8 0.0 8.8 10 0 0 10 10 10 1 Ankyrin repeat Ank_2 PF12796.7 EGB11119.1 - 7e-14 52.2 0.0 9.4e-07 29.3 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB11119.1 - 1e-12 48.3 0.3 0.0007 20.1 0.0 5.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB11119.1 - 5.3e-08 33.0 2.0 9.2e-05 22.6 0.1 4.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) zf-MYND PF01753.18 EGB11119.1 - 5.1e-06 26.5 10.9 1e-05 25.5 10.9 1.5 1 0 0 1 1 1 1 MYND finger Ank PF00023.30 EGB11119.1 - 6e-06 26.5 6.1 0.0015 18.9 0.1 5.7 6 0 0 6 6 6 1 Ankyrin repeat zf-C6H2 PF15801.5 EGB11119.1 - 2.2e-05 24.7 9.4 5.1e-05 23.5 9.4 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding DUF1843 PF08898.10 EGB11119.1 - 0.01 16.3 4.1 24 5.5 0.3 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) zf-HIT PF04438.16 EGB11119.1 - 3.3 7.7 6.6 7.1 6.6 6.6 1.5 1 0 0 1 1 1 0 HIT zinc finger Fer2 PF00111.27 EGB11120.1 - 1.1e-12 47.7 1.0 4.1e-12 45.9 1.0 1.9 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ephrin_rec_like PF07699.13 EGB11121.1 - 1.1e-13 50.7 32.1 5.3e-05 22.9 4.1 4.7 2 2 2 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 EGB11121.1 - 3.4e-07 30.1 24.5 0.024 14.6 0.9 4.2 4 0 0 4 4 4 4 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EGB11121.1 - 0.001 19.4 23.5 0.18 12.2 0.1 6.0 2 2 4 6 6 6 3 TNFR/NGFR cysteine-rich region VSP PF03302.13 EGB11121.1 - 0.011 14.6 19.6 0.15 10.9 4.3 2.0 1 1 1 2 2 2 0 Giardia variant-specific surface protein Ephrin_rec_like PF07699.13 EGB11122.1 - 8.1e-22 76.7 39.6 7.9e-09 35.1 9.6 3.9 2 2 2 4 4 4 4 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB11122.1 - 1.1e-05 25.7 13.9 0.015 15.7 0.2 5.3 1 1 3 4 4 4 3 TNFR/NGFR cysteine-rich region Opy2 PF09463.10 EGB11122.1 - 0.0033 17.7 36.1 0.061 13.7 6.0 4.2 4 0 0 4 4 4 4 Opy2 protein VSP PF03302.13 EGB11122.1 - 0.17 10.7 41.5 0.18 10.6 26.2 1.9 1 1 0 1 1 1 0 Giardia variant-specific surface protein ATP-gua_Ptrans PF00217.19 EGB11123.1 - 3e-56 190.2 0.0 3.9e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 EGB11123.1 - 5.1e-10 39.6 0.1 1.7e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Ank_2 PF12796.7 EGB11124.1 - 0.02 15.5 0.0 0.029 15.0 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB11124.1 - 0.038 14.5 0.1 1.2 10.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat dTDP_sugar_isom PF00908.17 EGB11124.1 - 0.045 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Sulfotransfer_3 PF13469.6 EGB11125.1 - 4.6e-19 69.7 4.2 5.2e-10 40.1 1.3 3.2 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB11125.1 - 1.4e-12 47.6 0.0 5.9e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase domain Sulphotransf PF09037.10 EGB11125.1 - 6.8e-05 22.5 0.0 0.45 10.0 0.0 3.7 3 2 0 3 3 3 2 Stf0 sulphotransferase DCX PF03607.17 EGB11125.1 - 0.0019 18.3 0.0 3.7 7.7 0.0 2.8 2 0 0 2 2 2 2 Doublecortin SnoaL PF07366.12 EGB11125.1 - 0.0039 17.0 0.4 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase DUF2859 PF11072.8 EGB11125.1 - 0.023 14.5 0.1 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) SspK PF08176.12 EGB11125.1 - 0.13 12.6 0.1 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Small acid-soluble spore protein K family WD40 PF00400.32 EGB11126.1 - 4e-27 93.9 17.6 3.9e-05 24.3 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11126.1 - 0.00013 22.2 1.2 0.91 9.9 0.3 3.9 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB11126.1 - 0.011 14.4 0.0 4 6.0 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF1348 PF07080.11 EGB11126.1 - 0.55 10.2 3.2 3.5 7.6 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1348) zf-MYND PF01753.18 EGB11127.1 - 4.2e-08 33.1 11.6 4.2e-08 33.1 11.6 3.3 3 0 0 3 3 3 1 MYND finger zf-C3HC4_3 PF13920.6 EGB11127.1 - 1.1e-07 31.5 13.3 1.1e-07 31.5 13.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2378 PF09536.10 EGB11127.1 - 0.0033 17.3 1.6 0.43 10.4 0.4 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF2378) zf-RING_5 PF14634.6 EGB11127.1 - 0.0056 16.6 12.0 0.0056 16.6 12.0 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGB11127.1 - 0.056 13.2 2.7 0.2 11.5 2.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger Trm112p PF03966.16 EGB11127.1 - 0.067 13.8 1.6 7.3 7.3 0.1 2.8 2 0 0 2 2 2 0 Trm112p-like protein FH2 PF02181.23 EGB11128.1 - 1.1e-16 61.0 0.0 3.1e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 Formin Homology 2 Domain Arm PF00514.23 EGB11128.1 - 0.00016 21.6 0.1 0.00086 19.3 0.1 2.3 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat PH PF00169.29 EGB11128.1 - 0.0029 18.1 0.0 0.005 17.3 0.0 1.4 1 0 0 1 1 1 1 PH domain CCDC53 PF10152.9 EGB11128.1 - 0.27 11.6 0.0 0.27 11.6 0.0 4.5 4 1 0 4 4 4 0 Subunit CCDC53 of WASH complex adh_short PF00106.25 EGB11130.1 - 1.1e-24 87.0 6.8 2.7e-18 66.1 5.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGB11130.1 - 9.8e-15 54.7 7.3 9.7e-09 35.1 3.8 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGB11130.1 - 0.049 13.1 1.0 0.3 10.5 1.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA-synt_His PF13393.6 EGB11131.1 - 3.3e-41 141.6 0.0 5.1e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EGB11131.1 - 7.7e-09 35.8 0.0 7.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGB11131.1 - 2.9e-06 27.3 0.0 6.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 EGB11131.1 - 7e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) VCBS PF13517.6 EGB11132.1 - 4.6e-50 168.1 112.9 1.5e-08 35.1 7.9 12.2 5 4 7 12 12 12 12 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Laminin_G_3 PF13385.6 EGB11132.1 - 1.1e-47 162.0 30.2 1.5e-18 67.4 1.5 4.7 4 0 0 4 4 4 3 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EGB11132.1 - 1.2e-09 38.8 0.1 0.028 15.0 0.0 3.5 3 0 0 3 3 3 3 Laminin G domain Pentaxin PF00354.17 EGB11132.1 - 4.2e-07 29.8 0.0 0.013 15.1 0.2 3.8 3 2 0 3 3 3 2 Pentaxin family FG-GAP PF01839.23 EGB11132.1 - 0.015 15.4 146.0 0.017 15.3 3.0 15.9 15 0 0 15 15 15 0 FG-GAP repeat BBS2_Mid PF14783.6 EGB11132.1 - 0.64 10.1 11.4 48 4.0 0.0 6.6 7 1 1 8 8 8 0 Ciliary BBSome complex subunit 2, middle region Peptidase_C1 PF00112.23 EGB11133.1 - 2.2e-64 217.5 0.0 2.8e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB11133.1 - 3.2e-06 27.5 0.0 5.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB11133.1 - 0.00059 18.7 0.2 0.12 11.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PPR_2 PF13041.6 EGB11134.1 - 4.2e-07 30.0 0.0 0.00012 22.1 0.0 3.5 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.20 EGB11134.1 - 2.3e-06 27.5 0.0 0.27 11.6 0.0 4.0 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 EGB11134.1 - 3.2e-06 27.1 0.0 0.0005 20.1 0.0 2.7 2 1 2 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EGB11134.1 - 0.00045 19.7 0.1 0.026 13.9 0.0 3.8 3 1 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP Gal-3-0_sulfotr PF06990.11 EGB11134.1 - 0.00084 18.3 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Nop14 PF04147.12 EGB11134.1 - 3.5 5.7 4.8 4.9 5.2 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family Arylsulfotrans PF05935.11 EGB11135.1 - 3.1e-08 32.9 0.0 5.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB11135.1 - 0.059 12.7 0.1 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) DUF4452 PF14618.6 EGB11135.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) DUF842 PF05811.13 EGB11136.1 - 1.1e-34 119.0 5.9 1.2e-34 118.8 5.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Phasin PF05597.11 EGB11136.1 - 0.046 13.7 0.3 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Hydrolase_4 PF12146.8 EGB11137.1 - 7.8e-06 25.3 0.1 1.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Polyketide_cyc2 PF10604.9 EGB11137.1 - 0.0003 21.1 0.3 0.0003 21.1 0.3 2.6 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Ser_hydrolase PF06821.13 EGB11137.1 - 0.00043 20.2 0.0 0.0015 18.4 0.0 1.9 1 0 0 1 1 1 1 Serine hydrolase DEAD PF00270.29 EGB11138.1 - 1.2e-17 64.3 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11138.1 - 3.6e-15 56.3 0.0 6.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGB11138.1 - 0.00036 21.2 0.5 0.00036 21.2 0.5 2.0 2 0 0 2 2 2 1 RecQ zinc-binding HEM4 PF02602.15 EGB11138.1 - 0.014 14.7 2.7 1.3 8.3 0.0 3.2 3 1 0 3 3 3 0 Uroporphyrinogen-III synthase HemD ResIII PF04851.15 EGB11138.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Psb28 PF03912.14 EGB11139.1 - 1.3e-37 128.2 0.1 1.6e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 Psb28 protein PI3_PI4_kinase PF00454.27 EGB11140.1 - 2e-47 162.1 0.0 2.5e-45 155.3 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EGB11140.1 - 0.044 13.1 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Beach PF02138.18 EGB11141.1 - 1e-105 353.1 0.0 1.2e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Glycolytic PF00274.19 EGB11142.1 - 1.2e-05 24.3 0.0 4.4e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Fructose-bisphosphate aldolase class-I AAA_6 PF12774.7 EGB11143.1 - 7.1e-154 511.6 0.0 2.1e-151 503.5 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB11143.1 - 2.2e-134 448.6 6.8 2.2e-134 448.6 6.8 2.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGB11143.1 - 1.6e-100 335.7 0.2 3.4e-99 331.4 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGB11143.1 - 9e-94 314.1 0.0 9.7e-93 310.7 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGB11143.1 - 3.6e-84 281.3 2.8 3.6e-84 281.3 2.8 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGB11143.1 - 4.5e-72 241.3 0.1 5e-68 228.2 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB11143.1 - 1.3e-51 174.7 0.0 3e-51 173.5 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB11143.1 - 9.9e-47 157.9 0.0 3.7e-41 139.9 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGB11143.1 - 9.4e-43 146.5 10.2 2e-42 145.4 10.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EGB11143.1 - 3.1e-30 104.9 0.2 1.2e-29 103.0 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGB11143.1 - 2.7e-18 66.0 0.0 1.1e-17 64.0 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB11143.1 - 2.2e-12 47.2 0.0 0.012 15.7 0.0 5.0 4 1 0 4 4 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB11143.1 - 7.1e-06 26.3 0.3 0.049 13.9 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGB11143.1 - 9.5e-06 26.2 0.5 0.0082 16.7 0.0 4.5 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 EGB11143.1 - 5.5e-05 22.3 1.7 0.0048 16.0 0.1 3.3 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA PF00004.29 EGB11143.1 - 0.00034 21.1 0.7 0.82 10.1 0.0 3.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGB11143.1 - 0.0051 17.2 1.0 18 5.7 0.0 5.6 6 0 0 6 6 5 0 AAA ATPase domain AAA_19 PF13245.6 EGB11143.1 - 0.016 15.6 2.9 0.63 10.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EGB11143.1 - 0.026 14.2 0.6 0.13 11.9 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EGB11143.1 - 0.031 14.7 0.4 13 6.3 0.0 3.8 3 0 0 3 3 3 0 RNA helicase BLOC1_2 PF10046.9 EGB11143.1 - 0.034 14.5 4.2 7.6 6.9 0.2 4.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF853 PF05872.12 EGB11143.1 - 0.041 12.5 2.5 4 5.9 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_30 PF13604.6 EGB11143.1 - 0.058 13.1 3.1 9.6 5.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 EGB11143.1 - 0.15 12.1 0.2 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EGB11143.1 - 0.16 12.5 0.0 20 5.7 0.0 3.2 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 EGB11143.1 - 0.21 11.3 1.5 19 4.9 0.1 3.5 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 EGB11143.1 - 0.34 9.8 2.9 1 8.2 0.1 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 EGB11143.1 - 0.57 10.2 2.5 5.1 7.1 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PI3K_P85_iSH2 PF16454.5 EGB11143.1 - 1.2 8.7 6.7 0.28 10.8 0.3 3.2 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AAA_23 PF13476.6 EGB11144.1 - 2.7e-24 86.8 0.0 3.3e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGB11144.1 - 7.6e-06 25.5 0.0 2.1e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGB11144.1 - 3.4e-05 23.7 0.0 0.00018 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EGB11144.1 - 0.0046 17.5 0.2 0.0073 16.8 0.2 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB11144.1 - 0.0086 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB11144.1 - 0.033 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB11144.1 - 0.056 13.8 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 EGB11144.1 - 0.088 12.4 0.2 0.26 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGB11144.1 - 0.088 13.1 0.3 0.13 12.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGB11144.1 - 0.1 12.3 0.3 0.37 10.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EGB11145.1 - 1.4e-07 31.6 0.0 3e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EGB11145.1 - 2.8e-06 26.9 0.0 3.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGB11145.1 - 0.0014 18.4 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGB11145.1 - 0.0015 18.4 0.1 0.0023 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EGB11145.1 - 0.092 13.3 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter JmjC PF02373.22 EGB11146.1 - 0.0092 16.4 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF2897 PF11446.8 EGB11146.1 - 0.34 10.8 1.3 0.79 9.6 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) XRN_N PF03159.18 EGB11147.1 - 3.6e-74 249.2 0.0 4.3e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EGB11147.1 - 9.2e-21 74.3 0.0 1.3e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Xrn1 helical domain SPASM PF13186.6 EGB11147.1 - 0.14 12.7 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain PseudoU_synth_1 PF01416.20 EGB11148.1 - 2e-21 76.5 0.0 8.2e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase Acetyltransf_6 PF13480.7 EGB11148.1 - 0.029 14.5 1.3 0.076 13.2 1.2 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GCV_T PF01571.21 EGB11149.1 - 4e-58 196.8 0.1 2.5e-57 194.2 0.0 1.9 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 EGB11149.1 - 1.8e-51 175.8 4.6 2.7e-51 175.2 4.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 EGB11149.1 - 4.4e-14 52.5 0.1 8.4e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 EGB11149.1 - 8.4e-13 48.1 0.0 3.6e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Thi4 PF01946.17 EGB11149.1 - 1.1e-05 24.7 0.1 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGB11149.1 - 5.8e-05 22.4 4.6 0.00017 20.8 4.6 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGB11149.1 - 7e-05 23.0 0.1 0.00023 21.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGB11149.1 - 0.00023 20.5 0.3 0.006 15.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB11149.1 - 0.00038 19.8 1.0 0.01 15.1 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 EGB11149.1 - 0.0028 16.6 1.0 0.073 11.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EGB11149.1 - 0.0032 16.6 1.8 0.86 8.6 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 EGB11149.1 - 0.0037 16.4 1.0 0.025 13.7 1.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGB11149.1 - 0.03 13.0 0.1 0.061 12.0 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 EGB11149.1 - 0.048 13.6 1.6 0.81 9.7 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGB11149.1 - 0.06 12.6 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGB11149.1 - 0.068 12.8 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 EGB11149.1 - 0.081 12.3 3.1 0.038 13.4 0.9 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EGB11149.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGB11149.1 - 0.19 12.2 0.5 0.53 10.7 0.0 2.0 2 0 0 2 2 1 0 Putative NAD(P)-binding TauD PF02668.16 EGB11150.1 - 5.5e-28 98.5 0.0 1.1e-27 97.6 0.0 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGB11150.1 - 2.4e-05 24.9 0.0 6.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) HD PF01966.22 EGB11150.1 - 0.00014 22.1 1.5 0.00029 21.0 1.5 1.5 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 EGB11150.1 - 0.012 15.3 0.2 0.062 13.0 0.1 2.2 2 0 0 2 2 2 0 HD domain ADH_N_2 PF16884.5 EGB11150.1 - 0.022 14.6 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PG_isomerase_N PF18353.1 EGB11150.1 - 0.053 13.9 1.3 5.8 7.4 0.0 3.3 3 0 0 3 3 3 0 Phosphoglucose isomerase N-terminal domain THB PF18362.1 EGB11150.1 - 0.11 12.1 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Tri-helix bundle domain VCBS PF13517.6 EGB11151.1 - 5.3e-29 100.6 49.7 1.1e-10 41.9 6.5 6.0 4 1 1 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB11151.1 - 6.2e-10 39.0 77.8 0.0076 16.4 4.4 8.0 7 0 0 7 7 7 6 FG-GAP repeat TRP PF06011.12 EGB11151.1 - 0.0052 15.6 1.0 0.0095 14.7 1.0 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Gly_rich_SFCGS PF14272.6 EGB11151.1 - 0.078 13.0 0.4 0.34 10.9 0.4 2.1 1 0 0 1 1 1 0 Glycine-rich SFCGS BBS2_Mid PF14783.6 EGB11151.1 - 1.2 9.3 2.5 71 3.5 0.0 4.1 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Glyco_trans_1_4 PF13692.6 EGB11152.1 - 9.5e-26 90.8 0.2 3.2e-25 89.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB11152.1 - 1.4e-24 86.6 0.0 2.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGB11152.1 - 2e-24 86.5 0.2 3.3e-24 85.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGB11152.1 - 4.4e-15 56.5 2.0 4.4e-15 56.5 2.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGB11152.1 - 2.4e-10 40.7 0.0 6.5e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 PhyH PF05721.13 EGB11153.1 - 1.8e-09 38.2 0.3 7e-09 36.2 0.3 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EGB11153.1 - 0.04 12.7 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Pro_isomerase PF00160.21 EGB11154.1 - 3.6e-41 141.1 0.0 4.1e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DNA_topoisoIV PF00521.20 EGB11155.1 - 2e-109 366.3 0.0 2.7e-109 365.9 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGB11155.1 - 1.4e-44 151.4 0.4 4.9e-44 149.7 0.0 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGB11155.1 - 7.4e-24 84.2 0.0 1.6e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EGB11155.1 - 1.2e-12 48.3 0.0 5.6e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGB11155.1 - 2.2e-06 27.8 0.0 7.5e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Myosin_TH1 PF06017.13 EGB11155.1 - 0.018 14.7 0.2 5 6.8 0.0 2.9 3 0 0 3 3 3 0 Unconventional myosin tail, actin- and lipid-binding GLTP PF08718.11 EGB11156.1 - 1.6e-10 41.5 0.0 2.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) UBA PF00627.31 EGB11157.1 - 0.00043 20.1 0.1 0.00043 20.1 0.1 3.1 3 0 0 3 3 3 1 UBA/TS-N domain Glycos_transf_2 PF00535.26 EGB11157.1 - 0.0049 16.7 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 WD40 PF00400.32 EGB11158.1 - 8.1e-38 127.8 5.4 0.00025 21.8 2.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11158.1 - 8.9e-11 41.9 0.3 0.0076 16.5 0.1 5.5 1 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB11158.1 - 5.6e-05 22.3 0.0 0.81 8.6 0.0 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGB11158.1 - 0.0011 18.4 0.0 0.4 10.0 0.0 3.0 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_C552 PF02335.15 EGB11158.1 - 0.029 13.3 0.1 0.043 12.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c552 HCO3_cotransp PF00955.21 EGB11160.1 - 1e-97 328.1 14.4 7.6e-55 186.7 0.4 2.2 1 1 1 2 2 2 2 HCO3- transporter family 60KD_IMP PF02096.20 EGB11161.1 - 3.4e-45 153.9 0.0 4.3e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Sel1 PF08238.12 EGB11162.1 - 6.7e-08 33.0 5.7 0.012 16.3 0.0 5.4 5 0 0 5 5 5 2 Sel1 repeat PHD PF00628.29 EGB11162.1 - 0.00013 21.8 6.0 0.0007 19.4 6.6 2.0 2 0 0 2 2 2 1 PHD-finger TPR_1 PF00515.28 EGB11162.1 - 0.0015 18.3 0.4 0.0061 16.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11162.1 - 0.0019 18.2 1.3 0.006 16.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11162.1 - 0.0092 16.2 0.6 0.0092 16.2 0.6 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11162.1 - 0.081 13.0 0.2 0.26 11.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11162.1 - 0.12 12.6 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ABC_tran PF00005.27 EGB11163.1 - 3.4e-42 144.2 0.0 1.7e-19 70.7 0.0 3.9 3 1 0 3 3 3 3 ABC transporter AAA_21 PF13304.6 EGB11163.1 - 1.9e-16 60.8 0.2 0.0053 16.6 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB11163.1 - 4.3e-13 49.2 0.0 0.18 11.3 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGB11163.1 - 2.3e-08 34.8 0.0 0.0031 18.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGB11163.1 - 4e-08 32.9 0.1 0.0099 15.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB11163.1 - 5.9e-07 29.5 0.1 0.0046 16.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGB11163.1 - 1.4e-06 28.3 0.0 0.0063 16.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB11163.1 - 7.5e-06 26.4 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGB11163.1 - 1.9e-05 24.9 0.0 0.024 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGB11163.1 - 0.00015 21.6 0.0 0.5 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 EGB11163.1 - 0.00026 21.3 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB11163.1 - 0.00027 21.1 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB11163.1 - 0.00032 20.6 0.3 0.53 10.2 0.7 2.7 2 1 0 2 2 2 1 NACHT domain AAA PF00004.29 EGB11163.1 - 0.00047 20.6 0.0 0.53 10.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGB11163.1 - 0.00063 19.0 0.1 0.19 10.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGB11163.1 - 0.00082 19.7 0.1 2.3 8.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MeaB PF03308.16 EGB11163.1 - 0.0013 17.7 0.2 0.43 9.5 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGB11163.1 - 0.0016 18.2 0.0 1.1 9.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 EGB11163.1 - 0.0017 18.0 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGB11163.1 - 0.0023 18.5 0.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EGB11163.1 - 0.0056 16.9 0.0 0.88 9.8 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EGB11163.1 - 0.0061 16.1 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 EGB11163.1 - 0.0074 16.5 0.1 4.3 7.6 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 EGB11163.1 - 0.011 15.5 0.0 6.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 EGB11163.1 - 0.017 15.1 0.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGB11163.1 - 0.02 14.6 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGB11163.1 - 0.02 14.8 0.3 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Dynamin_N PF00350.23 EGB11163.1 - 0.025 14.6 0.1 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.6 EGB11163.1 - 0.026 14.5 0.0 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EGB11163.1 - 0.031 13.1 0.6 1.7 7.4 0.2 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 EGB11163.1 - 0.033 13.4 0.1 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 EGB11163.1 - 0.045 13.8 0.2 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Adeno_IVa2 PF02456.15 EGB11163.1 - 0.064 12.0 0.1 7.8 5.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 EGB11163.1 - 0.068 12.9 0.4 7.5 6.2 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein MukB PF04310.12 EGB11163.1 - 0.084 12.7 0.1 12 5.7 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal G-alpha PF00503.20 EGB11163.1 - 0.09 11.9 0.0 10 5.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Viral_helicase1 PF01443.18 EGB11163.1 - 0.092 12.5 0.0 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 EGB11163.1 - 0.12 11.7 0.1 2.2 7.5 0.0 2.5 3 0 0 3 3 2 0 Septin GTP_EFTU PF00009.27 EGB11163.1 - 0.13 11.8 0.0 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_13 PF13166.6 EGB11163.1 - 0.14 10.8 0.0 5.6 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EGB11163.1 - 0.15 11.6 0.1 8.8 5.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran_Xtn PF12848.7 EGB11163.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 EGB11163.1 - 0.16 11.5 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGB11163.1 - 0.24 11.2 0.7 6.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EGB11163.1 - 0.46 10.1 1.7 7.5 6.1 0.1 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain HSCB_C PF07743.13 EGB11165.1 - 5.4e-12 46.0 0.1 1.3e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGB11165.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ResIII PF04851.15 EGB11166.1 - 9.9e-19 68.0 0.0 1.4e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB11166.1 - 1.7e-18 67.0 0.0 2.9e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11166.1 - 1.5e-16 60.7 0.0 6.3e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGB11166.1 - 0.032 14.5 0.0 0.18 12.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain SWI2_SNF2 PF18766.1 EGB11166.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF2075 PF09848.9 EGB11166.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Exo_endo_phos PF03372.23 EGB11167.1 - 1.7e-09 37.5 7.3 7.4e-09 35.5 7.3 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family INCA1 PF15142.6 EGB11167.1 - 0.061 13.3 0.5 0.21 11.6 0.3 2.0 2 0 0 2 2 2 0 INCA1 ABC1 PF03109.16 EGB11168.1 - 6.1e-24 84.5 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB11168.1 - 3.2e-07 30.5 0.3 7.2e-06 26.1 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB11168.1 - 0.00071 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EGB11168.1 - 0.13 11.5 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 EGB11168.1 - 0.21 10.9 0.0 1.3 8.3 0.0 2.0 2 1 0 2 2 2 0 Protein kinase domain Histone_H2A_C PF16211.5 EGB11169.1 - 8.3e-20 70.2 1.4 2e-19 69.0 1.4 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB11169.1 - 5.1e-12 46.3 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB11169.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ank_4 PF13637.6 EGB11170.1 - 5.3e-23 81.1 7.6 1.3e-13 51.1 0.7 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11170.1 - 7.2e-18 65.0 0.3 1.1e-16 61.2 0.4 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB11170.1 - 1.6e-17 63.3 5.1 7.9e-10 38.8 1.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB11170.1 - 2.8e-17 62.3 3.3 9.1e-09 35.4 0.4 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EGB11170.1 - 1.8e-16 58.5 0.3 0.00018 21.7 0.1 3.4 4 0 0 4 4 4 3 Ankyrin repeat amfpi-1 PF12190.8 EGB11170.1 - 0.11 13.1 0.0 12 6.6 0.0 2.7 1 1 2 3 3 3 0 Fungal protease inhibitor Histone PF00125.24 EGB11171.1 - 6.1e-53 178.7 1.1 6.8e-53 178.5 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGB11171.1 - 0.00076 20.1 3.0 0.00098 19.7 3.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGB11171.1 - 0.00088 19.4 0.3 0.0014 18.7 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB11171.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGB11171.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGB11171.1 - 0.032 14.3 0.1 0.057 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Tyr-DNA_phospho PF06087.12 EGB11172.1 - 9.7e-13 47.8 0.0 2.5e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EGB11172.1 - 0.0019 18.1 0.0 0.41 10.5 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain Histone_H2A_C PF16211.5 EGB11173.1 - 7.9e-21 73.5 1.4 2.2e-20 72.1 1.4 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB11173.1 - 1e-11 45.3 0.0 1.2e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB11173.1 - 0.0015 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAD_binding_4 PF01565.23 EGB11175.1 - 4.5e-11 42.7 0.0 3.2e-10 39.9 0.4 2.3 3 0 0 3 3 3 1 FAD binding domain FAD-oxidase_C PF02913.19 EGB11175.1 - 0.066 12.8 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Aminotran_1_2 PF00155.21 EGB11176.1 - 1.2e-84 284.6 0.0 1.3e-84 284.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 EGB11177.1 - 1.8e-60 205.1 0.0 2.1e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGB11177.1 - 4.5e-09 36.1 0.8 6.7e-09 35.5 0.8 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGB11177.1 - 0.0002 20.0 0.0 0.00031 19.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGB11177.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V TylF PF05711.11 EGB11178.1 - 1e-49 169.2 0.0 1.7e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) TTL PF03133.15 EGB11178.1 - 1.7e-36 125.8 0.0 2.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Cupin_8 PF13621.6 EGB11178.1 - 7.1e-11 42.3 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB11178.1 - 0.00029 20.4 0.1 0.00054 19.5 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DAGK_cat PF00781.24 EGB11180.1 - 2.4e-27 95.1 0.3 3.5e-27 94.5 0.3 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Glyco_hydro_32N PF00251.20 EGB11181.1 - 1.8e-16 60.6 0.3 2.1e-16 60.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HCV_NS5a_C PF12941.7 EGB11181.1 - 0.052 13.4 0.1 0.066 13.1 0.1 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region AAA_21 PF13304.6 EGB11182.1 - 2.6e-11 43.9 0.0 3.4e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EGB11182.1 - 1.8e-10 41.4 0.0 2.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 EGB11182.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF4281 PF14108.6 EGB11183.1 - 1.8e-29 102.6 2.4 2.8e-29 102.0 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) PI31_Prot_N PF11566.8 EGB11184.1 - 0.037 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal Pyrophosphatase PF00719.19 EGB11185.1 - 6.8e-47 159.2 0.0 8.3e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Aminotran_1_2 PF00155.21 EGB11186.1 - 9.7e-33 113.8 0.0 1.3e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EGB11186.1 - 0.00066 18.4 0.0 0.025 13.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III Beta_elim_lyase PF01212.21 EGB11186.1 - 0.0029 16.9 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase SHMT PF00464.19 EGB11186.1 - 0.011 14.3 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydroxymethyltransferase SGS PF05002.15 EGB11187.1 - 4.1e-29 100.5 2.6 4.1e-29 100.5 2.6 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 EGB11187.1 - 3e-13 50.6 1.4 3e-13 50.6 1.4 1.7 2 0 0 2 2 2 1 CS domain TPR_1 PF00515.28 EGB11187.1 - 2.4e-08 33.4 10.4 0.00032 20.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11187.1 - 7.4e-05 22.6 11.8 0.0077 16.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Pox_RNA_pol PF03293.14 EGB11187.1 - 7.9e-05 22.4 0.2 0.00014 21.6 0.2 1.3 1 0 0 1 1 1 1 Poxvirus DNA-directed RNA polymerase, 18 kD subunit TPR_8 PF13181.6 EGB11187.1 - 0.0021 18.1 2.4 1.5 9.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11187.1 - 0.0081 16.8 4.0 0.0081 16.8 4.0 2.8 3 1 1 4 4 4 2 Tetratricopeptide repeat CHAD PF05235.14 EGB11187.1 - 0.024 14.6 0.4 3.1 7.7 0.0 2.1 2 0 0 2 2 2 0 CHAD domain TPR_11 PF13414.6 EGB11187.1 - 0.11 12.2 2.4 0.9 9.3 1.2 2.7 2 1 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 EGB11187.1 - 0.12 12.6 10.8 1.1 9.5 5.7 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB11187.1 - 0.63 10.2 5.6 2.1 8.6 2.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11187.1 - 4.1 8.0 10.2 3.1 8.4 2.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB11187.1 - 5.3 8.1 13.0 1.9 9.5 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 EGB11188.1 - 1.2e-48 166.5 0.0 9.2e-37 127.4 0.0 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB11188.1 - 3.7e-10 39.9 0.0 7.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB11188.1 - 7.1e-09 35.7 0.3 0.00011 21.9 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB11188.1 - 4.6e-08 33.5 0.1 7.3e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB11188.1 - 8.8e-06 25.1 0.0 2.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EGB11188.1 - 4.7e-05 22.0 0.0 8.7e-05 21.1 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like HI0933_like PF03486.14 EGB11188.1 - 0.002 16.9 0.1 0.0032 16.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGB11188.1 - 0.0082 15.3 0.1 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EGB11188.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EGB11188.1 - 0.021 14.1 0.2 0.058 12.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family MCRA PF06100.11 EGB11188.1 - 0.1 11.4 0.0 0.54 9.0 0.0 1.8 2 0 0 2 2 2 0 MCRA family NAD_binding_2 PF03446.15 EGB11189.1 - 9.1e-32 110.4 0.6 1.6e-31 109.6 0.6 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGB11189.1 - 1.9e-30 105.6 0.5 4.1e-30 104.5 0.5 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGB11189.1 - 9.6e-08 32.5 0.0 2.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGB11189.1 - 0.019 14.4 0.4 0.061 12.7 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGB11189.1 - 0.073 13.9 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh PF00984.19 EGB11189.1 - 0.085 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF5570 PF17731.1 EGB11189.1 - 1.6 8.8 5.1 0.67 10.1 1.8 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5570) Pterin_bind PF00809.22 EGB11190.1 - 4.2e-71 239.5 0.0 5.4e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGB11190.1 - 1.9e-30 105.6 0.0 3.3e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) tRNA_int_end_N2 PF12928.7 EGB11191.1 - 2.3e-11 43.7 0.0 4.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Peptidase_M20 PF01546.28 EGB11194.1 - 1.3e-29 103.4 2.6 1.7e-29 103.0 2.6 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGB11194.1 - 5.9e-11 42.2 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PDZ_6 PF17820.1 EGB11195.1 - 0.13 12.1 0.4 0.38 10.6 0.4 1.7 1 0 0 1 1 1 0 PDZ domain TFIIF_alpha PF05793.12 EGB11195.1 - 0.86 8.1 5.1 1.2 7.6 5.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VWA_CoxE PF05762.14 EGB11196.1 - 0.08 12.3 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Metallophos PF00149.28 EGB11199.1 - 6.7e-07 30.0 0.0 9.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 EGB11199.1 - 0.052 12.6 0.0 0.083 11.9 0.0 1.4 2 0 0 2 2 2 0 PhoD-like phosphatase HNH_5 PF14279.6 EGB11201.1 - 4.2e-19 68.1 0.3 6e-19 67.7 0.3 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EGB11201.1 - 1.9e-13 50.3 0.2 2.6e-13 49.9 0.2 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 EGB11201.1 - 7.4e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 EGB11202.1 - 2.6e-43 148.3 0.0 3e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11202.1 - 1.4e-23 83.5 0.0 1.7e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Inositol_P PF00459.25 EGB11203.1 - 4.5e-35 121.5 1.7 1e-34 120.3 1.7 1.5 1 0 0 1 1 1 1 Inositol monophosphatase family cNMP_binding PF00027.29 EGB11203.1 - 1.1e-19 70.2 0.9 3.8e-14 52.5 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DUF4272 PF14094.6 EGB11203.1 - 0.026 13.8 2.4 0.03 13.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) cNMP_binding PF00027.29 EGB11204.1 - 2.2e-06 27.6 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGB11205.1 - 4.1e-61 206.7 0.0 4.8e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11205.1 - 8.6e-30 103.9 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGB11205.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YukC PF10140.9 EGB11205.1 - 0.072 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC UDPGP PF01704.18 EGB11206.1 - 4.2e-12 45.4 0.0 6.6e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase BSD PF03909.17 EGB11206.1 - 0.00067 19.6 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 BSD domain Apolipoprotein PF01442.18 EGB11206.1 - 0.058 13.3 1.6 0.13 12.1 1.6 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.11 EGB11206.1 - 0.16 12.5 0.2 0.34 11.5 0.2 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Ribosomal_L38e PF01781.18 EGB11207.1 - 3.1e-33 113.7 2.5 3.4e-33 113.6 2.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family GBP PF02263.19 EGB11208.1 - 3.4e-34 118.3 0.0 4.2e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGB11208.1 - 0.00058 19.9 0.0 0.0008 19.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGB11208.1 - 0.071 13.2 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Dynamin family RHD3 PF05879.12 EGB11208.1 - 0.11 10.7 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Sel1 PF08238.12 EGB11209.1 - 1.4e-06 28.8 9.8 1.2 9.9 0.0 4.8 5 0 0 5 5 5 3 Sel1 repeat TPR_2 PF07719.17 EGB11209.1 - 0.045 13.9 0.2 0.045 13.9 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11209.1 - 0.047 13.9 3.0 0.34 11.2 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11209.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TB2_DP1_HVA22 PF03134.19 EGB11210.1 - 0.0034 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RCDG1 PF15725.5 EGB11210.1 - 0.37 11.2 5.1 1.4 9.4 5.1 2.0 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein PTEN_C2 PF10409.9 EGB11211.1 - 3e-08 33.5 0.0 5.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein UCH PF00443.29 EGB11213.1 - 3.4e-31 108.7 0.0 4.7e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB11213.1 - 7.3e-14 52.1 0.0 4.7e-11 42.9 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GST_C_3 PF14497.6 EGB11214.1 - 3.9e-05 23.8 0.0 5.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB11214.1 - 0.00029 20.8 0.1 0.00061 19.8 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB11214.1 - 0.062 13.7 0.0 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain HECT PF00632.25 EGB11215.1 - 2.3e-83 280.2 0.0 2.8e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MerR-DNA-bind PF09278.11 EGB11217.1 - 0.03 14.9 1.4 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 MerR, DNA binding LPMO_10 PF03067.15 EGB11218.1 - 1.5e-21 78.0 0.0 6.9e-21 75.8 0.0 2.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_18 PF00704.28 EGB11218.1 - 1.4e-15 57.8 6.9 1.6e-14 54.4 6.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 2OG-FeII_Oxy_3 PF13640.6 EGB11218.1 - 3.2e-06 28.0 0.0 0.0065 17.3 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Sulfotransfer_2 PF03567.14 EGB11218.1 - 9.2e-06 25.7 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Kunitz_BPTI PF00014.23 EGB11218.1 - 0.021 15.0 9.9 1.5 9.1 0.1 3.8 3 0 0 3 3 3 0 Kunitz/Bovine pancreatic trypsin inhibitor domain PLDc PF00614.22 EGB11219.1 - 6e-10 38.9 0.8 8.3e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 Phospholipase D Active site motif PLDc_2 PF13091.6 EGB11219.1 - 3.7e-05 23.6 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 EGB11220.1 - 3.8e-07 30.1 0.0 6.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 EGB11220.1 - 9.2e-07 28.8 0.1 1.7e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif FA_desaturase PF00487.24 EGB11221.1 - 5.4e-26 92.0 11.8 6.9e-26 91.6 11.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Sel1 PF08238.12 EGB11222.1 - 4.4e-25 87.6 16.9 7.7e-10 39.1 0.1 4.6 4 1 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB11222.1 - 0.00018 22.1 11.5 0.12 13.0 5.7 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11222.1 - 0.00035 20.8 7.4 0.01 16.1 1.6 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGB11222.1 - 0.00059 20.0 1.5 5 7.7 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11222.1 - 0.016 15.1 12.9 0.017 14.9 0.2 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11222.1 - 0.02 15.1 5.6 0.21 11.9 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11222.1 - 0.028 14.2 0.5 0.028 14.2 0.5 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 EGB11222.1 - 0.084 12.9 4.9 0.19 11.8 0.2 3.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain PDDEXK_10 PF07788.11 EGB11222.1 - 0.2 11.6 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily TPR_2 PF07719.17 EGB11222.1 - 0.23 11.7 19.2 0.26 11.5 0.6 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11222.1 - 0.28 11.3 9.4 2.4 8.4 0.2 4.1 4 2 2 6 6 6 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 EGB11223.1 - 1.2e-36 126.6 13.7 2e-36 125.8 13.7 1.4 1 0 0 1 1 1 1 Subtilase family Peptidase_S8_N PF16361.5 EGB11223.1 - 5.9e-07 30.1 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal of Subtilase family Glyco_transf_90 PF05686.12 EGB11224.1 - 7.1e-18 64.7 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Ras PF00071.22 EGB11225.1 - 9.3e-55 184.6 0.0 1.1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB11225.1 - 1.9e-33 115.2 0.0 2.5e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB11225.1 - 4.1e-09 36.1 0.0 5e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGB11225.1 - 2.4e-05 24.3 0.0 0.029 14.3 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGB11225.1 - 0.0003 20.9 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGB11225.1 - 0.0032 16.8 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGB11225.1 - 0.0034 17.8 0.1 0.0057 17.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGB11225.1 - 0.011 15.7 0.0 0.022 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGB11225.1 - 0.019 14.5 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 EGB11225.1 - 0.022 14.3 0.0 0.075 12.6 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TniB PF05621.11 EGB11225.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EGB11225.1 - 0.041 14.1 0.0 0.14 12.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Exotox-A_target PF09102.10 EGB11225.1 - 0.045 13.7 1.0 0.17 11.9 0.4 1.9 1 1 1 2 2 2 0 Exotoxin A, targeting NACHT PF05729.12 EGB11225.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 NACHT domain Gemini_V2 PF01524.17 EGB11225.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Geminivirus V2 protein Sigma54_activat PF00158.26 EGB11225.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EGB11225.1 - 0.18 12.3 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EGB11225.1 - 0.21 11.3 0.0 0.55 10.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TMA7 PF09072.10 EGB11226.1 - 0.18 12.7 1.1 0.66 10.9 1.1 1.9 1 0 0 1 1 1 0 Translation machinery associated TMA7 IQ PF00612.27 EGB11227.1 - 2.2e-06 27.0 29.5 0.012 15.4 1.8 7.4 7 0 0 7 7 7 4 IQ calmodulin-binding motif EF-hand_6 PF13405.6 EGB11227.1 - 1.7e-05 24.4 0.0 0.4 10.7 0.0 5.1 5 0 0 5 5 5 1 EF-hand domain EF-hand_7 PF13499.6 EGB11227.1 - 0.00097 19.5 0.2 0.72 10.3 0.2 3.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB11227.1 - 0.01 15.4 0.3 4 7.2 0.0 4.7 5 0 0 5 5 5 1 EF hand KCNQC3-Ank-G_bd PF11956.8 EGB11227.1 - 0.12 12.6 0.4 2.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 UPF0242 PF06785.11 EGB11227.1 - 2.1 8.4 5.6 3.7 7.6 5.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 EGB11227.1 - 3.8 7.4 11.1 6.1 6.7 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C1 PF00112.23 EGB11228.1 - 7.4e-16 58.9 0.0 8.5e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB11228.1 - 0.016 14.0 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family SGP PF17228.2 EGB11228.1 - 0.034 15.0 4.4 0.044 14.6 4.4 1.2 1 0 0 1 1 1 0 Sulphur globule protein HI0933_like PF03486.14 EGB11229.1 - 3.8e-105 351.9 0.0 4.3e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGB11229.1 - 1.5e-09 37.9 6.4 6.9e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGB11229.1 - 3.5e-09 36.3 1.8 1.3e-07 31.1 1.9 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB11229.1 - 5e-05 22.7 0.3 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGB11229.1 - 0.00017 21.6 2.7 0.0012 18.8 0.2 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGB11229.1 - 0.00073 18.7 4.8 0.00073 18.7 4.8 2.2 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EGB11229.1 - 0.0023 17.1 7.9 0.14 11.3 3.9 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGB11229.1 - 0.0028 17.1 9.1 0.0056 16.1 9.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGB11229.1 - 0.0045 16.3 0.0 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DUF348 PF03990.14 EGB11229.1 - 0.01 15.6 1.3 0.032 14.0 1.3 1.8 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Trp_halogenase PF04820.14 EGB11229.1 - 0.068 12.0 4.2 0.73 8.6 1.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 EGB11229.1 - 0.65 10.6 2.1 14 6.3 0.9 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Pribosyltran PF00156.27 EGB11230.1 - 6e-08 32.4 0.1 9.9e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EGB11230.1 - 6.4e-08 32.8 0.0 9.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EGB11230.1 - 0.0039 17.1 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase PRTase_2 PF15609.6 EGB11230.1 - 0.2 11.1 0.0 4.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl transferase Aminotran_4 PF01063.19 EGB11231.1 - 1.3e-21 77.5 0.0 1.7e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV LMF1 PF06762.14 EGB11232.1 - 9.5e-117 390.8 0.1 1.3e-116 390.4 0.1 1.2 1 0 0 1 1 1 1 Lipase maturation factor WD40 PF00400.32 EGB11233.1 - 6.8e-24 83.7 18.1 2e-07 31.6 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11233.1 - 4e-14 52.7 0.4 0.012 15.9 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB11233.1 - 0.00087 19.2 0.0 0.085 12.7 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGB11233.1 - 0.042 11.8 0.0 0.99 7.3 0.0 2.2 2 0 0 2 2 2 0 IKI3 family MOZART1 PF12554.8 EGB11234.1 - 1.3e-19 69.7 0.1 1.7e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated PP-binding PF00550.25 EGB11234.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 Phosphopantetheine attachment site ARL2_Bind_BART PF11527.8 EGB11235.1 - 2.7e-05 24.2 0.1 4.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART tRNA-synt_2c PF01411.19 EGB11236.1 - 1.1e-180 601.9 0.0 1.7e-180 601.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 EGB11236.1 - 6.8e-10 39.5 1.6 6.8e-10 39.5 1.6 2.6 3 1 0 3 3 3 1 DHHA1 domain tRNA_SAD PF07973.14 EGB11236.1 - 5.7e-08 32.7 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CCB1 PF12046.8 EGB11237.1 - 1.3e-55 187.3 0.1 1.6e-55 187.0 0.1 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B DUF4131 PF13567.6 EGB11237.1 - 0.14 11.8 0.8 9.5 5.8 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) zf-MYND PF01753.18 EGB11238.1 - 0.00016 21.7 11.4 0.0003 20.8 11.4 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EGB11238.1 - 0.0052 16.6 10.1 0.0088 15.9 10.1 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF973 PF06157.11 EGB11240.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Diphthamide_syn PF01866.17 EGB11241.1 - 5.6e-104 347.8 0.0 6.4e-104 347.6 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF2427 PF10348.9 EGB11242.1 - 2 8.2 4.5 4.7 7.1 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) LEM PF03020.15 EGB11243.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 LEM domain DUF2358 PF10184.9 EGB11246.1 - 2.7e-10 40.5 0.0 4.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) PGAP1 PF07819.13 EGB11246.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGB11246.1 - 1e-05 26.3 18.2 1e-05 26.3 18.2 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB11246.1 - 0.0025 17.5 1.8 0.0055 16.4 0.2 2.4 2 2 1 3 3 3 1 alpha/beta hydrolase fold SnoaL_2 PF12680.7 EGB11246.1 - 0.0035 18.0 0.9 0.079 13.6 0.0 3.1 2 1 1 3 3 3 1 SnoaL-like domain Ser_hydrolase PF06821.13 EGB11246.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase DUF2974 PF11187.8 EGB11246.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EGB11246.1 - 0.019 14.8 0.3 0.036 13.9 0.3 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 EGB11246.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EGB11246.1 - 0.097 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pro-kuma_activ PF09286.11 EGB11247.1 - 3.7e-21 75.9 0.0 1e-20 74.5 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGB11247.1 - 0.00074 18.9 0.3 0.0018 17.6 0.3 1.6 1 0 0 1 1 1 1 Subtilase family Mei5_like PF17021.5 EGB11247.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative double-strand recombination repair-like PI3_PI4_kinase PF00454.27 EGB11248.1 - 1.6e-29 103.5 0.0 3.4e-23 82.7 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase CS PF04969.16 EGB11249.1 - 1.8e-11 44.9 0.0 9.1e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 CS domain AAA_6 PF12774.7 EGB11250.1 - 1.8e-144 480.7 0.0 1.2e-143 478.0 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 EGB11250.1 - 4.3e-100 334.3 0.0 3.1e-99 331.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGB11250.1 - 4.8e-89 298.6 0.0 1.7e-88 296.8 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGB11250.1 - 5.5e-89 297.1 2.6 3.8e-87 291.0 3.8 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region DHC_N2 PF08393.13 EGB11250.1 - 2.1e-80 270.8 0.4 2.1e-80 270.8 0.4 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 EGB11250.1 - 3.3e-71 238.5 0.1 8.6e-67 224.1 0.0 5.1 5 0 0 5 5 5 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB11250.1 - 5e-53 179.3 0.0 9.7e-53 178.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGB11250.1 - 6.3e-49 166.8 17.1 1.4e-48 165.7 17.1 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGB11250.1 - 6.4e-42 142.4 0.0 7.3e-39 132.5 0.0 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Es2 PF09751.9 EGB11250.1 - 5.3e-24 85.8 0.0 3.5e-15 56.7 0.0 2.4 1 1 1 2 2 2 2 Nuclear protein Es2 Dynein_AAA_lid PF17852.1 EGB11250.1 - 8.3e-23 80.9 0.0 2.3e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGB11250.1 - 1e-22 80.2 0.0 3.6e-22 78.4 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB11250.1 - 1.6e-14 54.1 0.1 0.00032 20.7 0.0 5.6 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EGB11250.1 - 4.2e-10 40.2 1.0 0.0043 17.5 0.0 4.5 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGB11250.1 - 3.5e-06 27.6 1.5 0.21 12.1 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA_22 PF13401.6 EGB11250.1 - 2.6e-05 24.5 2.5 1.9 8.8 0.0 4.9 5 0 0 5 5 5 2 AAA domain ABC_tran PF00005.27 EGB11250.1 - 0.00036 21.1 3.4 0.025 15.1 0.0 3.9 5 0 0 5 5 2 1 ABC transporter AAA_33 PF13671.6 EGB11250.1 - 0.00065 19.9 0.1 6.3 7.0 0.0 4.1 3 0 0 3 3 3 0 AAA domain Sec34 PF04136.15 EGB11250.1 - 0.00092 19.1 2.2 0.00092 19.1 2.2 2.7 2 0 0 2 2 2 1 Sec34-like family AAA_16 PF13191.6 EGB11250.1 - 0.0011 19.4 1.6 0.83 10.0 0.0 5.3 5 0 0 5 5 5 1 AAA ATPase domain T2SSE PF00437.20 EGB11250.1 - 0.0011 18.0 3.4 0.042 12.9 0.0 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EGB11250.1 - 0.003 17.9 0.2 23 5.5 0.0 3.8 3 0 0 3 3 3 0 RNA helicase Cytidylate_kin PF02224.18 EGB11250.1 - 0.01 15.6 1.0 1.7 8.3 0.0 3.5 3 0 0 3 3 3 0 Cytidylate kinase TsaE PF02367.17 EGB11250.1 - 0.026 14.5 1.6 3.2 7.7 0.1 3.4 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EGB11250.1 - 0.031 14.0 0.3 8.1 6.3 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Trans_reg_C PF00486.28 EGB11250.1 - 0.12 12.4 0.0 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal AAA_28 PF13521.6 EGB11250.1 - 0.14 12.4 0.1 72 3.6 0.0 4.0 3 0 0 3 3 3 0 AAA domain DUF948 PF06103.11 EGB11250.1 - 1.1 9.5 5.1 3.1 8.1 1.0 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NACHT PF05729.12 EGB11250.1 - 3.1 7.7 4.5 2.1 8.2 0.0 3.1 4 0 0 4 4 3 0 NACHT domain tRNA_synthFbeta PF17759.1 EGB11251.1 - 1.2e-44 152.3 0.0 1.7e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGB11251.1 - 8e-32 109.3 0.1 2.8e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGB11251.1 - 1.5e-24 86.7 0.0 2.4e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGB11251.1 - 4.3e-11 43.0 0.0 1.4e-09 38.1 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF5335 PF17269.2 EGB11251.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) 6PF2K PF01591.18 EGB11252.1 - 5.4e-56 189.4 0.0 6.8e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGB11252.1 - 1.7e-22 80.0 0.0 1.4e-17 64.1 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGB11252.1 - 0.00048 20.3 0.0 0.00098 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Aminotran_3 PF00202.21 EGB11253.1 - 3.9e-81 272.8 0.0 4.7e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.21 EGB11254.1 - 1.8e-74 250.8 0.0 2e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III CH PF00307.31 EGB11255.1 - 3.8e-19 68.9 0.0 4.6e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EGB11255.1 - 0.00028 21.1 0.0 0.00044 20.5 0.0 1.2 1 0 0 1 1 1 1 CDC24 Calponin Focal_AT PF03623.13 EGB11255.1 - 0.056 13.4 0.1 5.6 7.0 0.0 2.2 1 1 1 2 2 2 0 Focal adhesion targeting region UreF PF01730.16 EGB11255.1 - 0.062 13.9 0.1 0.094 13.3 0.1 1.4 1 0 0 1 1 1 0 UreF P16-Arc PF04699.14 EGB11256.1 - 3.8e-18 66.4 0.0 3.9e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF1198 PF06711.11 EGB11256.1 - 0.092 12.8 0.0 0.097 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Utp12 PF04003.12 EGB11256.1 - 0.098 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Dip2/Utp12 Family PDZ_6 PF17820.1 EGB11257.1 - 3.1e-07 30.1 0.4 8.4e-07 28.7 0.4 1.8 1 0 0 1 1 1 1 PDZ domain HEAT PF02985.22 EGB11257.1 - 5.6e-07 29.3 43.4 0.27 11.6 0.4 8.8 8 0 0 8 8 8 6 HEAT repeat PDZ PF00595.24 EGB11257.1 - 8.5e-06 26.0 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain HEAT_2 PF13646.6 EGB11257.1 - 0.00014 22.2 7.8 0.00014 22.2 7.8 7.5 3 3 4 7 7 7 4 HEAT repeats Peptidase_C1 PF00112.23 EGB11258.1 - 1.9e-51 175.3 7.6 2.2e-51 175.0 7.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB11258.1 - 3.4e-07 30.6 0.0 5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB11258.1 - 5.3e-05 22.2 1.3 0.00012 21.0 0.2 1.8 2 0 0 2 2 2 1 Peptidase C1-like family SUI1 PF01253.22 EGB11259.1 - 2.5e-18 66.4 0.9 3.3e-18 66.0 0.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pkinase PF00069.25 EGB11261.1 - 2.2e-56 191.1 0.0 2.5e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11261.1 - 2.4e-24 86.1 0.0 2.8e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KIAA1430 PF13879.6 EGB11262.1 - 3.2e-27 95.3 18.7 4.5e-27 94.8 18.7 1.2 1 0 0 1 1 1 1 KIAA1430 homologue COMMD1_N PF17221.3 EGB11262.1 - 0.0048 17.2 0.5 0.0048 17.2 0.5 1.5 2 0 0 2 2 2 1 COMMD1 N-terminal domain CobU PF02283.16 EGB11262.1 - 0.65 9.5 3.4 0.87 9.1 3.4 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase BPL_N PF09825.9 EGB11262.1 - 5.1 6.1 7.1 6.1 5.8 7.1 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Pkinase PF00069.25 EGB11263.1 - 2.6e-44 151.6 0.0 3.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11263.1 - 3.5e-29 101.9 0.0 4.2e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB11263.1 - 5e-05 22.7 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB11263.1 - 0.00045 19.1 0.0 0.00062 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Cellulase PF00150.18 EGB11264.1 - 2.7e-12 46.7 0.1 4.6e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 EGB11264.1 - 0.0024 17.3 0.0 0.032 13.7 0.0 2.2 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel X8 PF07983.13 EGB11264.1 - 0.0062 17.2 0.4 0.013 16.2 0.4 1.6 1 0 0 1 1 1 1 X8 domain DEAD PF00270.29 EGB11265.1 - 2.2e-43 148.1 0.0 2.2e-42 144.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11265.1 - 2.1e-29 102.1 0.0 5.4e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EGB11265.1 - 0.013 14.3 0.0 0.37 9.5 0.0 2.4 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 EGB11265.1 - 0.027 13.7 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGB11265.1 - 0.071 13.1 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PRAI PF00697.22 EGB11265.1 - 0.1 12.4 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase WD40 PF00400.32 EGB11266.1 - 3e-25 88.0 27.8 0.0092 16.8 0.2 11.1 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11266.1 - 2e-06 28.0 0.5 16 5.9 0.0 6.1 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EGB11266.1 - 0.0052 15.2 0.0 0.17 10.1 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 EGB11266.1 - 0.042 14.4 2.0 14 6.3 0.0 4.8 5 0 0 5 5 5 0 PQQ-like domain Asp_Arg_Hydrox PF05118.15 EGB11267.1 - 1.9e-48 164.2 0.0 3.8e-48 163.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_17 PF13431.6 EGB11267.1 - 6.4e-08 32.5 0.1 0.11 12.9 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11267.1 - 6.2e-05 23.4 3.5 6.2e-05 23.4 3.5 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11267.1 - 0.00056 19.6 11.3 1.2 9.1 0.7 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11267.1 - 0.00074 20.1 4.2 0.00074 20.1 4.2 7.0 5 2 2 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11267.1 - 0.00094 19.1 27.0 1 9.6 2.4 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11267.1 - 0.005 17.1 1.4 0.005 17.1 1.4 4.8 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11267.1 - 0.0072 16.3 9.7 3 8.1 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11267.1 - 0.046 13.9 6.2 5.1 7.6 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Cupin_2 PF07883.11 EGB11267.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Cupin domain TPR_11 PF13414.6 EGB11267.1 - 0.24 11.1 2.7 0.44 10.3 0.8 2.4 2 0 0 2 2 2 0 TPR repeat PDZ PF00595.24 EGB11268.1 - 0.0016 18.8 0.1 0.0032 17.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EGB11268.1 - 0.0023 17.7 0.7 0.0063 16.3 0.7 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGB11268.1 - 0.0029 17.9 0.3 0.006 16.9 0.3 1.5 1 0 0 1 1 1 1 PDZ domain Rbsn PF11464.8 EGB11268.1 - 0.07 12.9 1.7 0.3 10.8 0.5 2.4 2 0 0 2 2 2 0 Rabenosyn Rab binding domain FKBP_C PF00254.28 EGB11269.1 - 1.1e-23 83.4 0.0 1.1e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CLP_protease PF00574.23 EGB11270.1 - 1.3e-53 181.6 0.0 3.7e-53 180.1 0.0 1.6 1 1 0 1 1 1 1 Clp protease cNMP_binding PF00027.29 EGB11273.1 - 0.00057 19.9 0.0 0.0019 18.2 0.0 2.0 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain RGS PF00615.19 EGB11273.1 - 0.019 15.2 1.8 0.078 13.2 1.8 1.9 1 1 0 1 1 1 0 Regulator of G protein signaling domain Imm5 PF14423.6 EGB11273.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm5 Ku PF02735.16 EGB11274.1 - 7.3e-12 45.4 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain DSPc PF00782.20 EGB11274.1 - 1.1e-11 44.6 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB11274.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LRR_6 PF13516.6 EGB11275.1 - 9.8e-11 40.8 15.3 0.12 12.5 0.0 8.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_8 PF13855.6 EGB11275.1 - 0.0026 17.5 0.0 3.1 7.6 0.0 4.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.33 EGB11275.1 - 0.13 12.9 0.0 40 5.3 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat Inositol_P PF00459.25 EGB11277.1 - 5.2e-28 98.3 2.2 1.2e-27 97.1 2.2 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family APH PF01636.23 EGB11277.1 - 6e-13 49.3 9.5 6e-13 49.3 9.5 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGB11277.1 - 2.4e-08 33.7 0.0 7.2e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGB11277.1 - 0.00028 19.9 0.0 0.00042 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EGB11277.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EGB11277.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EGB11277.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Ank_2 PF12796.7 EGB11278.1 - 1e-29 102.9 0.0 6.6e-15 55.5 0.0 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB11278.1 - 4.1e-15 55.6 0.2 7.7e-07 29.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11278.1 - 1.8e-13 49.4 0.1 4.2e-05 23.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EGB11278.1 - 1.6e-11 44.5 0.1 1.4e-05 25.6 0.0 2.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB11278.1 - 2.1e-11 43.7 0.1 0.00031 21.0 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Gal-3-0_sulfotr PF06990.11 EGB11279.1 - 0.00097 18.1 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase TPP_enzyme_N PF02776.18 EGB11279.1 - 0.03 13.9 6.2 0.045 13.4 6.2 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Sulfotransfer_4 PF17784.1 EGB11280.1 - 0.011 15.6 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Sulfotransferase domain Glyoxalase_4 PF13669.6 EGB11281.1 - 3.8e-25 88.3 0.1 6.2e-25 87.6 0.0 1.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 EGB11281.1 - 1.1e-10 41.8 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGB11281.1 - 2.7e-09 37.4 0.1 3.8e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EGB11281.1 - 0.0002 22.1 0.2 0.00034 21.4 0.2 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain DUF1338 PF07063.13 EGB11281.1 - 0.0084 15.3 0.0 0.71 9.0 0.0 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF1338) Anoctamin PF04547.12 EGB11282.1 - 2e-93 313.7 0.0 2.4e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PA PF02225.22 EGB11282.1 - 0.18 11.9 0.2 0.47 10.5 0.2 1.7 1 0 0 1 1 1 0 PA domain GTP_EFTU PF00009.27 EGB11283.1 - 4.6e-43 147.0 0.0 6.3e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGB11283.1 - 4.1e-24 84.7 0.0 7.9e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGB11283.1 - 6.9e-23 80.5 0.0 2e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFTUD2 PF16004.5 EGB11283.1 - 1.1e-22 80.9 0.2 2.6e-22 79.7 0.2 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU_D2 PF03144.25 EGB11283.1 - 2.4e-08 34.3 0.0 5.9e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGB11283.1 - 3.5e-07 30.2 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGB11283.1 - 0.00082 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EGB11283.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Ras family SRPRB PF09439.10 EGB11283.1 - 0.087 12.3 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit polyprenyl_synt PF00348.17 EGB11284.1 - 1.2e-55 188.4 0.1 1.5e-55 188.1 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase UbiA PF01040.18 EGB11284.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 UbiA prenyltransferase family C2 PF00168.30 EGB11285.1 - 1.7e-29 102.1 0.0 6.6e-15 55.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain Cass2 PF14526.6 EGB11285.1 - 0.043 14.0 0.0 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Integron-associated effector binding protein RPA_interact_N PF14766.6 EGB11285.1 - 0.4 10.3 2.9 5.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Metallophos PF00149.28 EGB11286.1 - 3.7e-09 37.4 0.0 5.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4381 PF14316.6 EGB11286.1 - 0.22 11.8 2.8 0.41 10.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PTP_N PF12453.8 EGB11286.1 - 0.28 10.9 2.9 1.5 8.6 0.8 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal Telomere_Sde2_2 PF13297.6 EGB11287.1 - 4.8e-19 67.8 2.6 1e-18 66.7 2.6 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SPRY PF00622.28 EGB11287.1 - 1.1e-17 64.2 0.0 3.4e-17 62.7 0.1 1.7 2 0 0 2 2 2 1 SPRY domain Sde2_N_Ubi PF13019.6 EGB11287.1 - 6.4e-14 52.1 6.2 6.4e-14 52.1 6.2 2.4 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Hep_59 PF07052.11 EGB11287.1 - 0.15 12.8 0.5 0.31 11.8 0.5 1.5 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 PDZ_6 PF17820.1 EGB11288.1 - 5.2e-16 58.2 9.5 7.4e-06 25.7 1.8 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 EGB11288.1 - 3.1e-11 43.4 0.2 0.00045 20.5 0.1 3.3 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 EGB11288.1 - 7.2e-09 35.9 2.1 0.0085 16.4 0.1 3.3 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EGB11288.1 - 6.3e-06 26.1 0.1 0.066 13.2 0.0 3.3 3 0 0 3 3 3 2 Tricorn protease PDZ domain Cu_bind_like PF02298.17 EGB11288.1 - 0.035 14.1 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Plastocyanin-like domain DUF2868 PF11067.8 EGB11288.1 - 0.2 11.1 1.7 0.38 10.2 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Thioredoxin_8 PF13905.6 EGB11290.1 - 0.022 15.0 0.0 0.032 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like UPF0004 PF00919.20 EGB11291.1 - 3.4e-18 65.5 0.1 6.1e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 EGB11291.1 - 8.1e-14 52.3 0.0 1.9e-13 51.1 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Biotin_lipoyl PF00364.22 EGB11292.1 - 6.4e-12 45.1 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme F5_F8_type_C PF00754.25 EGB11292.1 - 4.9e-07 29.9 0.5 1.5e-06 28.4 0.5 1.8 1 0 0 1 1 1 1 F5/8 type C domain Biotin_lipoyl_2 PF13533.6 EGB11292.1 - 0.012 15.4 0.5 2.6 7.9 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.6 EGB11292.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EGB11292.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein PhyH PF05721.13 EGB11294.1 - 1.5e-06 28.7 0.1 1.2e-05 25.7 0.1 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_1_2 PF00155.21 EGB11295.1 - 1.2e-54 185.9 0.0 1.4e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGB11295.1 - 1.5e-05 24.5 0.2 3.1e-05 23.5 0.2 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGB11295.1 - 2.5e-05 23.7 0.9 7.1e-05 22.2 0.8 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGB11295.1 - 0.00028 20.0 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGB11295.1 - 0.00044 18.9 0.0 0.00096 17.8 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EGB11295.1 - 0.021 13.6 0.1 0.078 11.7 0.1 1.8 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Mastoparan PF08249.11 EGB11295.1 - 0.084 13.6 0.7 0.084 13.6 0.7 2.9 3 0 0 3 3 3 0 Mastoparan protein Arylsulfotrans PF05935.11 EGB11296.1 - 2.9e-06 26.4 0.0 0.0012 17.9 0.0 2.9 2 1 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EGB11296.1 - 0.00088 18.7 0.0 0.055 12.8 0.1 2.6 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) fn3 PF00041.21 EGB11296.1 - 0.00097 19.4 0.4 0.0032 17.8 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain RNase_T PF00929.24 EGB11297.1 - 2.4e-18 67.2 0.0 2.7e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EGB11297.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 1 1 2 2 2 0 3'-5' exonuclease AAA_6 PF12774.7 EGB11298.1 - 1.5e-138 461.3 0.0 8e-137 455.6 0.0 3.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 EGB11298.1 - 3.6e-97 324.7 0.0 7.7e-97 323.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 EGB11298.1 - 2.4e-94 316.7 0.4 2.4e-94 316.7 0.4 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGB11298.1 - 3.6e-81 271.5 1.8 9.2e-81 270.2 1.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 EGB11298.1 - 2.4e-70 237.3 17.8 5.2e-70 236.2 17.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EGB11298.1 - 1.2e-68 231.7 0.0 1.1e-67 228.5 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGB11298.1 - 2.6e-61 206.3 2.7 2.4e-56 190.1 0.7 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB11298.1 - 1.2e-47 161.8 0.0 1.3e-46 158.4 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB11298.1 - 1.4e-41 141.3 0.0 9e-37 125.8 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Kelch_5 PF13854.6 EGB11298.1 - 4.1e-28 96.9 0.4 4.9e-05 23.2 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGB11298.1 - 7e-27 92.8 1.1 1e-05 25.6 0.1 5.9 5 0 0 5 5 5 4 Kelch motif AAA_lid_1 PF17857.1 EGB11298.1 - 2.8e-24 85.2 0.2 1.5e-23 82.9 0.2 2.4 1 0 0 1 1 1 1 AAA+ lid domain Kelch_4 PF13418.6 EGB11298.1 - 1.9e-20 72.6 0.4 2.4e-05 24.2 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EGB11298.1 - 1.1e-19 70.2 9.0 0.00011 22.4 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain AAA_5 PF07728.14 EGB11298.1 - 4.1e-19 68.9 0.1 6e-09 36.0 0.0 5.7 4 2 0 4 4 4 3 AAA domain (dynein-related subfamily) Kelch_2 PF07646.15 EGB11298.1 - 9.1e-18 63.5 4.2 0.0011 18.9 0.0 5.0 4 0 0 4 4 4 4 Kelch motif Dynein_AAA_lid PF17852.1 EGB11298.1 - 2.7e-17 63.1 0.1 9.2e-17 61.3 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Filamin PF00630.19 EGB11298.1 - 4.1e-17 62.9 0.1 6.8e-16 59.0 0.0 2.6 2 0 0 2 2 2 1 Filamin/ABP280 repeat Kelch_1 PF01344.25 EGB11298.1 - 9.6e-17 60.3 1.0 0.0002 20.9 0.0 5.1 5 0 0 5 5 4 3 Kelch motif AAA_22 PF13401.6 EGB11298.1 - 5.4e-07 29.9 0.0 4.2 7.6 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EGB11298.1 - 2.8e-05 24.6 0.6 7.1 7.0 0.0 5.7 5 0 0 5 5 5 0 AAA ATPase domain AAA_33 PF13671.6 EGB11298.1 - 0.00016 21.8 1.4 0.62 10.2 0.0 4.3 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 EGB11298.1 - 0.00018 22.1 0.3 15 6.1 0.1 4.9 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 EGB11298.1 - 0.00028 20.3 2.1 21 4.4 0.0 5.0 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EGB11298.1 - 0.0019 17.7 0.6 12 5.3 0.0 4.4 4 0 0 4 4 4 0 PhoH-like protein PHA_synth_III_E PF09712.10 EGB11298.1 - 0.0041 16.3 0.1 0.013 14.6 0.1 1.9 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) AAA_24 PF13479.6 EGB11298.1 - 0.0042 16.8 0.1 48 3.6 0.0 4.7 4 1 0 4 4 4 0 AAA domain TsaE PF02367.17 EGB11298.1 - 0.0044 17.0 2.2 13 5.8 0.0 5.1 5 0 0 5 5 5 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EGB11298.1 - 0.0055 17.1 0.3 36 4.8 0.0 4.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGB11298.1 - 0.006 16.3 0.0 1.4 8.6 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EGB11298.1 - 0.013 15.9 0.4 39 4.7 0.0 4.0 4 0 0 4 4 3 0 RNA helicase Sigma54_activ_2 PF14532.6 EGB11298.1 - 0.013 15.6 0.0 2.3 8.3 0.0 3.0 2 0 0 2 2 2 0 Sigma-54 interaction domain TIG PF01833.24 EGB11298.1 - 0.02 15.0 0.6 0.056 13.5 0.6 1.8 1 0 0 1 1 1 0 IPT/TIG domain Sigma54_activat PF00158.26 EGB11298.1 - 0.023 14.4 0.0 14 5.3 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 EGB11298.1 - 0.029 14.9 0.0 34 4.9 0.0 4.1 3 0 0 3 3 3 0 ABC transporter AAA_25 PF13481.6 EGB11298.1 - 0.039 13.5 0.4 14 5.2 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 EGB11298.1 - 0.058 13.1 5.5 9.2 5.9 0.0 4.5 5 1 0 5 5 4 0 AAA domain Invasin_D3 PF09134.10 EGB11298.1 - 0.069 13.5 1.0 0.28 11.5 0.1 2.5 2 0 0 2 2 1 0 Invasin, domain 3 BUD22 PF09073.10 EGB11298.1 - 0.1 11.9 11.5 1.1 8.5 0.2 2.4 2 0 0 2 2 2 0 BUD22 IQ PF00612.27 EGB11298.1 - 0.24 11.3 8.8 2.4 8.2 1.9 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_19 PF13245.6 EGB11298.1 - 0.71 10.2 4.8 29 5.0 0.0 4.6 5 0 0 5 5 3 0 AAA domain AAA_11 PF13086.6 EGB11298.1 - 7.5 6.2 7.0 1.9 8.2 0.0 3.3 3 0 0 3 3 2 0 AAA domain MORN PF02493.20 EGB11299.1 - 2.5e-12 45.9 14.9 3.7e-06 26.5 0.3 4.0 4 0 0 4 4 4 3 MORN repeat FKBP_C PF00254.28 EGB11300.1 - 6.4e-15 55.3 0.0 6.8e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sel1 PF08238.12 EGB11301.1 - 2.2e-21 75.8 30.8 6.7e-06 26.6 0.2 6.1 6 0 0 6 6 6 6 Sel1 repeat TPR_11 PF13414.6 EGB11301.1 - 4.3e-05 23.1 0.6 0.00077 19.1 1.1 2.7 3 0 0 3 3 3 1 TPR repeat HhH-GPD PF00730.25 EGB11302.1 - 4.4e-06 27.1 0.0 0.00027 21.4 0.0 3.2 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein TPR_19 PF14559.6 EGB11302.1 - 0.00014 22.3 3.5 0.00014 22.3 3.5 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11302.1 - 0.029 14.5 3.2 0.23 11.6 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EGB11303.1 - 2e-26 91.9 1.3 2.7e-13 49.9 0.1 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB11303.1 - 2.2e-19 69.5 0.0 2.1e-14 53.5 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGB11303.1 - 0.017 15.5 0.1 0.28 11.6 0.0 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGB11303.1 - 0.077 13.3 0.1 1.8 8.9 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Arginase PF00491.21 EGB11304.1 - 2.8e-11 43.5 0.0 3.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family Arginase PF00491.21 EGB11305.1 - 4.1e-35 121.7 0.1 5e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 Arginase family Abhydrolase_3 PF07859.13 EGB11306.1 - 3.6e-31 108.7 4.4 1.3e-21 77.5 4.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 EGB11306.1 - 0.082 11.8 0.1 3.9 6.2 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Hydrolase_4 PF12146.8 EGB11306.1 - 0.11 11.8 0.1 0.28 10.4 0.1 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_C1 PF00112.23 EGB11307.1 - 3.6e-57 194.0 0.5 4.8e-57 193.6 0.1 1.4 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB11307.1 - 3.9e-10 40.0 0.0 6.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) zf-MYND PF01753.18 EGB11308.1 - 3.9e-06 26.9 15.0 8e-06 25.8 15.0 1.6 1 0 0 1 1 1 1 MYND finger Rubis-subs-bind PF09273.11 EGB11308.1 - 0.015 16.0 0.1 0.035 14.8 0.1 1.6 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding zf-C6H2 PF15801.5 EGB11308.1 - 0.67 10.3 12.9 1.5 9.2 12.9 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding cNMP_binding PF00027.29 EGB11309.1 - 1.9e-35 120.8 1.8 1.1e-16 60.7 0.1 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain RGS PF00615.19 EGB11309.1 - 1.4e-12 48.0 0.0 3.8e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain K-cyclin_vir_C PF09080.10 EGB11309.1 - 0.0096 16.3 0.0 0.34 11.4 0.0 2.5 2 0 0 2 2 2 1 K cyclin, C terminal Ank PF00023.30 EGB11310.1 - 4.1e-13 49.1 1.0 1.8e-05 25.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGB11310.1 - 1.2e-11 44.9 0.2 1.4e-07 31.9 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB11310.1 - 1.3e-11 44.4 1.0 1.8e-06 28.1 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11310.1 - 7.3e-10 39.3 0.1 1.2e-08 35.4 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB11310.1 - 7.5e-10 38.2 0.9 3.7e-06 26.8 0.1 3.5 4 0 0 4 4 4 1 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 EGB11311.1 - 4.1e-14 53.2 0.0 8.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sulfotransfer_2 PF03567.14 EGB11311.1 - 6.6e-07 29.5 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family 2OG-FeII_Oxy_4 PF13661.6 EGB11311.1 - 2.2e-05 25.0 0.0 4.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EGB11311.1 - 0.00027 21.3 0.0 0.00069 20.0 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase SATase_N PF06426.14 EGB11312.1 - 4.6e-26 91.2 1.1 6.6e-26 90.7 1.1 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 EGB11312.1 - 1e-12 47.2 5.9 1.3e-07 31.1 0.4 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB11312.1 - 0.00023 20.8 9.7 0.00027 20.6 1.1 3.1 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase C2 PF00168.30 EGB11313.1 - 9.8e-22 77.2 0.0 1e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 C2 domain MORN PF02493.20 EGB11314.1 - 6.9e-32 107.4 39.5 8.7e-07 28.5 4.1 7.2 7 0 0 7 7 7 7 MORN repeat ATP_bind_1 PF03029.17 EGB11315.1 - 7.7e-71 238.7 0.0 8.9e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EGB11315.1 - 0.0013 19.3 0.0 0.0023 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGB11315.1 - 0.011 15.7 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_31 PF13614.6 EGB11315.1 - 0.014 15.3 0.0 0.44 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EGB11315.1 - 0.021 14.8 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGB11315.1 - 0.039 14.3 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ArsA_ATPase PF02374.15 EGB11315.1 - 0.041 13.1 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA PF00004.29 EGB11315.1 - 0.041 14.3 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EGB11315.1 - 0.044 13.5 0.0 0.17 11.6 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_VERT_large PF04441.13 EGB11315.1 - 0.098 10.9 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit AAA_22 PF13401.6 EGB11315.1 - 0.1 12.8 0.1 0.29 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain LacI PF00356.21 EGB11315.1 - 0.11 12.3 0.0 8.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family AAA_28 PF13521.6 EGB11315.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB11315.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EGB11315.1 - 0.17 11.4 0.0 9.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Herpes_TK PF00693.18 EGB11315.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus AAA_33 PF13671.6 EGB11315.1 - 0.19 11.9 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DHQ_synthase PF01761.20 EGB11316.1 - 5e-72 242.2 0.0 8.7e-72 241.4 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EGB11316.1 - 1.5e-08 34.7 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase IPPT PF01715.17 EGB11316.1 - 0.21 11.4 0.7 0.41 10.4 0.7 1.4 1 0 0 1 1 1 0 IPP transferase Ribosomal_S7 PF00177.21 EGB11317.1 - 2.5e-33 114.8 1.5 3.1e-33 114.5 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Rep-A_N PF04057.12 EGB11319.1 - 2.7e-18 65.9 0.0 4.1e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain SAM_1 PF00536.30 EGB11319.1 - 0.065 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pex14_N PF04695.13 EGB11319.1 - 5.1 7.7 10.1 9.8 6.8 5.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aldo_ket_red PF00248.21 EGB11320.1 - 7.2e-20 71.4 0.0 9.8e-19 67.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TAT_signal PF10518.9 EGB11320.1 - 0.032 14.1 4.2 0.032 14.1 4.2 4.0 4 0 0 4 4 4 0 TAT (twin-arginine translocation) pathway signal sequence TilS PF09179.11 EGB11320.1 - 0.41 11.2 5.3 11 6.6 0.0 3.0 3 0 0 3 3 3 0 TilS substrate binding domain Na_H_Exchanger PF00999.21 EGB11321.1 - 3.9e-58 197.1 34.0 4.9e-58 196.8 34.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cofac_haem_bdg PF04187.13 EGB11322.1 - 1.6e-18 67.5 0.0 2.6e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN Mem_trans PF03547.18 EGB11322.1 - 0.0016 16.9 4.4 0.0024 16.3 4.4 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF3338 PF11819.8 EGB11322.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) Isy1 PF06246.12 EGB11323.1 - 5.7e-78 262.0 0.0 6.2e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF305 PF03713.13 EGB11324.1 - 3.8e-23 82.3 0.0 1.9e-11 44.3 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF305) ShK PF01549.24 EGB11324.1 - 0.039 14.5 4.4 0.039 14.5 4.4 3.2 3 1 0 3 3 3 0 ShK domain-like Glycos_transf_2 PF00535.26 EGB11325.1 - 1.6e-06 28.0 0.4 2.8e-05 24.0 0.4 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB11325.1 - 3.2e-06 27.2 0.4 9.3e-06 25.7 0.4 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGB11325.1 - 1.6e-05 24.9 1.5 1.6e-05 24.9 1.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEP PF00610.21 EGB11325.1 - 0.0065 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_transf_21 PF13506.6 EGB11325.1 - 0.055 12.9 1.0 1.2 8.6 1.0 2.4 1 1 0 1 1 1 0 Glycosyl transferase family 21 Proteasome PF00227.26 EGB11326.1 - 5.9e-26 91.1 0.0 6.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Myosin_head PF00063.21 EGB11327.1 - 1.7e-43 148.8 0.0 1.9e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB11327.1 - 0.00083 19.8 0.1 0.00088 19.7 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.7 EGB11327.1 - 0.0034 16.3 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain Zeta_toxin PF06414.12 EGB11327.1 - 0.013 14.8 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EGB11327.1 - 0.03 14.6 0.1 0.035 14.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB11327.1 - 0.077 12.7 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGB11327.1 - 0.11 12.9 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 EGB11328.1 - 5e-36 124.2 0.0 5.7e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) PseudoU_synth_2 PF00849.22 EGB11329.1 - 1.5e-14 54.4 0.0 2.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EGB11329.1 - 5.4e-08 32.4 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain His_Phos_1 PF00300.22 EGB11330.1 - 1.8e-31 109.4 0.5 2.9e-20 72.8 0.2 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Amino_oxidase PF01593.24 EGB11331.1 - 2.1e-19 70.2 0.0 2.2e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB11331.1 - 2e-14 53.5 0.3 4.1e-14 52.6 0.1 1.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGB11331.1 - 0.00024 19.9 0.1 0.00031 19.6 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGB11331.1 - 0.00033 19.9 0.0 0.00044 19.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGB11331.1 - 0.00035 20.0 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGB11331.1 - 0.0013 18.1 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB11331.1 - 0.022 13.9 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 EGB11331.1 - 0.028 14.0 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB11331.1 - 0.042 14.4 0.1 0.058 14.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGB11331.1 - 0.17 11.1 0.0 0.71 9.1 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Kinesin PF00225.23 EGB11332.1 - 2.6e-95 319.2 0.0 3.1e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB11332.1 - 1.3e-21 77.1 0.0 1.7e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding Arm PF00514.23 EGB11333.1 - 9.3e-42 139.8 17.0 1.1e-05 25.3 0.1 8.5 7 1 0 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB11333.1 - 8.2e-09 35.7 1.2 0.078 13.4 0.0 4.9 2 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EGB11333.1 - 9e-06 25.5 7.0 0.024 14.9 0.1 5.2 6 0 0 6 6 6 2 HEAT repeat RICTOR_V PF14668.6 EGB11333.1 - 0.00016 21.9 0.4 5.8 7.2 0.0 4.1 4 1 1 5 5 5 3 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.6 EGB11333.1 - 0.003 18.0 14.4 0.045 14.3 0.1 5.8 6 2 2 8 8 8 1 HEAT-like repeat Cnd1 PF12717.7 EGB11333.1 - 0.039 14.0 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGB11333.1 - 0.13 10.8 0.2 0.72 8.3 0.1 1.9 1 1 1 2 2 2 0 Adaptin N terminal region DUF3396 PF11876.8 EGB11333.1 - 0.14 11.7 0.0 1.2 8.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3396) DIOX_N PF14226.6 EGB11334.1 - 1.1e-06 29.4 0.0 1.9e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGB11334.1 - 0.07 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3182 PF11379.8 EGB11334.1 - 0.089 11.7 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Alpha_adaptin_C PF02296.16 EGB11335.1 - 2.5e-09 37.3 0.0 7.9e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain PDZ_2 PF13180.6 EGB11335.1 - 0.017 15.5 0.1 0.56 10.6 0.0 2.9 3 0 0 3 3 3 0 PDZ domain DegS PF05384.11 EGB11335.1 - 2.9 7.4 8.4 6.9 6.1 8.4 1.6 1 0 0 1 1 1 0 Sensor protein DegS Ank PF00023.30 EGB11336.1 - 8.9e-15 54.4 2.9 4.1e-05 23.8 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EGB11336.1 - 9.8e-15 54.9 0.0 1.3e-10 41.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB11336.1 - 1.3e-12 46.7 5.9 0.0033 17.8 0.1 4.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EGB11336.1 - 6.4e-11 42.3 3.2 2.2e-06 27.8 0.5 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB11336.1 - 1.4e-08 35.1 1.2 2.7e-05 24.6 0.3 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) TPR_12 PF13424.6 EGB11337.1 - 7.8e-58 192.7 73.9 1.8e-12 47.4 3.6 9.3 7 2 3 10 10 10 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11337.1 - 3.9e-38 128.3 87.5 4.2e-05 23.3 1.0 14.3 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11337.1 - 1.5e-15 56.0 49.1 0.00025 20.9 0.3 11.3 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11337.1 - 7.1e-07 28.9 68.1 0.011 15.8 1.8 11.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11337.1 - 5.6e-06 26.0 38.0 0.0098 15.7 1.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11337.1 - 0.00067 19.7 14.7 0.51 10.7 0.1 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.18 EGB11337.1 - 0.018 15.1 2.9 2.4 8.3 0.1 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain FG-GAP_2 PF14312.6 EGB11338.1 - 4.8e-18 65.1 4.9 2e-17 63.2 4.9 2.2 1 0 0 1 1 1 1 FG-GAP repeat CBM_6 PF03422.15 EGB11338.1 - 0.045 14.0 1.7 0.75 10.1 0.4 3.4 3 0 0 3 3 3 0 Carbohydrate binding module (family 6) Sulfatase PF00884.23 EGB11339.1 - 2.4e-44 152.0 0.0 2.7e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase AFG1_ATPase PF03969.16 EGB11340.1 - 7.7e-91 304.7 0.0 1.4e-90 303.8 0.0 1.4 1 1 0 1 1 1 1 AFG1-like ATPase AAA_30 PF13604.6 EGB11340.1 - 0.024 14.4 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGB11340.1 - 0.041 14.2 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGB11340.1 - 0.078 13.4 0.6 1.7 9.0 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain Trp_Tyr_perm PF03222.13 EGB11341.1 - 4.1e-60 203.9 23.4 5e-60 203.6 23.4 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 EGB11341.1 - 9e-05 21.3 10.6 9e-05 21.3 10.6 2.5 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein VCBS PF13517.6 EGB11342.1 - 0.015 15.9 0.1 0.06 14.0 0.1 2.0 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB11342.1 - 0.048 13.8 1.7 0.2 11.8 1.7 2.1 1 0 0 1 1 1 0 FG-GAP repeat ABC1 PF03109.16 EGB11343.1 - 7.8e-19 68.0 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGB11343.1 - 1.2e-08 34.8 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EGB11343.1 - 2e-05 24.1 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 EGB11343.1 - 8e-05 22.7 2.6 8e-05 22.7 2.6 3.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EGB11343.1 - 0.0042 16.4 0.1 0.52 9.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Fructosamin_kin PF03881.14 EGB11343.1 - 0.14 11.3 0.0 7.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Sec7_N PF12783.7 EGB11344.1 - 7.9e-41 139.6 1.9 9e-41 139.4 1.9 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pox_polyA_pol_N PF12630.7 EGB11344.1 - 0.028 14.8 0.2 0.077 13.4 0.1 1.8 1 1 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Rif1_N PF12231.8 EGB11344.1 - 0.05 12.6 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Sec7 PF01369.20 EGB11345.1 - 2.9e-63 212.9 0.0 3.2e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Sec7 domain Cupin_8 PF13621.6 EGB11346.1 - 6.2e-15 55.6 0.2 6.7e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EGB11346.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.22 EGB11346.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 JmjC domain, hydroxylase GPI PF06560.11 EGB11346.1 - 0.089 12.1 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_1 PF00190.22 EGB11346.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin KH_1 PF00013.29 EGB11348.1 - 7.4e-58 192.3 8.0 5.2e-12 45.4 0.0 5.2 5 0 0 5 5 5 5 KH domain KH_2 PF07650.17 EGB11348.1 - 1.4e-16 60.1 8.7 0.0031 17.3 0.1 5.3 4 1 1 5 5 5 5 KH domain KH_4 PF13083.6 EGB11348.1 - 9.9e-05 22.1 6.8 4.6 7.2 0.1 5.2 5 0 0 5 5 5 3 KH domain KH_5 PF13184.6 EGB11348.1 - 0.0015 18.6 6.4 0.42 10.7 0.3 4.8 5 0 0 5 5 5 1 NusA-like KH domain HECT PF00632.25 EGB11349.1 - 7.6e-57 193.1 0.0 9e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Castor_Poll_mid PF06241.12 EGB11350.1 - 4.3e-26 90.9 0.0 1.2e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 EGB11350.1 - 5.9e-06 26.0 0.0 1.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 TrkA-C domain TetR_C_21 PF17926.1 EGB11350.1 - 0.08 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Dynein_C PF18199.1 EGB11351.1 - 0.013 14.8 0.3 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Dynein heavy chain C-terminal domain Aldolase_II PF00596.21 EGB11351.1 - 0.078 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Spectrin PF00435.21 EGB11351.1 - 0.31 11.6 3.4 21 5.7 0.3 2.7 2 0 0 2 2 2 0 Spectrin repeat Trm5_N PF18093.1 EGB11351.1 - 4.1 7.4 8.6 15 5.5 1.2 2.4 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain Ion_trans PF00520.31 EGB11352.1 - 1.1e-20 73.9 0.0 1.4e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGB11352.1 - 0.0025 16.6 1.7 0.0029 16.4 0.4 1.6 2 0 0 2 2 2 1 Polycystin cation channel zf-Nse PF11789.8 EGB11353.1 - 6.1e-13 48.4 0.6 1.1e-12 47.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGB11353.1 - 5e-05 23.2 0.4 9e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGB11353.1 - 0.0035 17.2 0.4 0.0073 16.1 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EGB11353.1 - 0.004 17.3 0.1 0.13 12.5 0.0 2.5 3 0 0 3 3 3 1 U-box domain Clathrin PF00637.20 EGB11354.1 - 1.3e-171 563.3 19.9 2e-27 95.8 3.6 8.3 8 1 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EGB11354.1 - 2.6e-27 94.5 0.0 1e-26 92.6 0.0 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 EGB11354.1 - 6.8e-15 54.6 0.0 4.8e-06 26.6 0.0 4.9 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.10 EGB11354.1 - 9.7e-05 21.7 0.0 0.00024 20.4 0.0 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 EGB11354.1 - 0.00096 18.3 1.9 0.3 10.1 0.1 2.6 2 0 0 2 2 2 2 Coatomer WD associated region Aldo_ket_red PF00248.21 EGB11355.1 - 1.4e-18 67.1 0.0 5.8e-13 48.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family SEP PF08059.13 EGB11356.1 - 2.7e-19 69.5 0.0 4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EGB11356.1 - 3.8e-10 39.8 0.0 5.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 UBX domain DUF4232 PF14016.6 EGB11356.1 - 0.088 13.0 3.5 0.05 13.7 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4232) DnaJ PF00226.31 EGB11357.1 - 1.7e-14 53.7 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Ank_4 PF13637.6 EGB11358.1 - 2.5e-11 43.9 0.2 0.00039 20.9 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11358.1 - 2.2e-09 37.7 0.0 2.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGB11358.1 - 9.4e-08 32.2 0.2 0.0052 17.2 0.1 3.4 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB11358.1 - 1.3e-07 31.3 0.0 0.18 12.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGB11358.1 - 1.5e-07 31.5 4.5 0.013 15.8 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) UCR_hinge PF02320.16 EGB11359.1 - 1.4e-17 63.6 0.8 1.8e-17 63.3 0.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UCH PF00443.29 EGB11360.1 - 3e-54 184.2 0.0 3.4e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB11360.1 - 1.1e-16 61.4 0.0 5.3e-15 55.8 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CAP_N PF01213.19 EGB11360.1 - 4.9 6.5 4.3 7.8 5.9 4.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ank_4 PF13637.6 EGB11361.1 - 5.4e-16 58.7 2.3 1.6e-08 34.9 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11361.1 - 9.6e-11 40.9 0.4 2.1e-05 24.5 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGB11361.1 - 3.2e-10 40.5 0.2 4.1e-10 40.1 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGB11361.1 - 2.5e-09 37.1 6.3 1.2e-05 25.5 0.5 2.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGB11361.1 - 1.5e-08 34.7 0.9 3.3e-08 33.6 0.3 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Peptidase_A4 PF01828.17 EGB11361.1 - 0.17 11.3 0.0 0.19 11.2 0.0 1.0 1 0 0 1 1 1 0 Peptidase A4 family KAP PF05804.12 EGB11362.1 - 2e-144 482.4 4.0 2.7e-144 482.0 4.0 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 EGB11362.1 - 4.6e-06 26.5 0.1 4.4 7.5 0.0 5.9 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EGB11362.1 - 0.014 14.9 8.7 0.82 9.1 0.1 4.1 3 1 2 5 5 5 0 Armadillo-like WAPL PF07814.13 EGB11362.1 - 0.11 11.3 1.9 1.9 7.2 1.9 2.6 1 1 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Kringle PF00051.18 EGB11363.1 - 2.7e-20 72.4 2.2 3e-20 72.3 2.2 1.0 1 0 0 1 1 1 1 Kringle domain DUF262 PF03235.14 EGB11364.1 - 2.4e-17 63.9 0.1 2.4e-17 63.9 0.1 7.0 9 0 0 9 9 9 1 Protein of unknown function DUF262 HNH_5 PF14279.6 EGB11364.1 - 3.3e-05 23.7 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EGB11364.1 - 8.4e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Pas_Saposin PF09016.10 EGB11364.1 - 0.00016 21.9 0.5 9.6 6.6 0.0 4.2 3 0 0 3 3 3 2 Pas factor saposin fold ATP-synt_E_2 PF08112.11 EGB11364.1 - 0.094 13.0 0.2 1.6e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 ATP synthase epsilon subunit Sulfatase PF00884.23 EGB11365.1 - 5.2e-56 190.3 0.0 4.9e-55 187.1 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB11365.1 - 0.015 14.9 0.0 0.1 12.2 0.0 1.9 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase HEAT PF02985.22 EGB11366.1 - 0.0066 16.6 1.3 0.0066 16.6 1.3 7.3 7 0 0 7 7 7 3 HEAT repeat BTB PF00651.31 EGB11367.1 - 9.7e-05 22.6 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain EGF_2 PF07974.13 EGB11368.1 - 1.1e-12 48.1 40.8 5.1e-05 23.5 8.5 4.2 4 0 0 4 4 4 4 EGF-like domain S_locus_glycop PF00954.20 EGB11368.1 - 0.0016 18.9 1.7 0.0016 18.9 1.7 3.3 3 0 0 3 3 3 1 S-locus glycoprotein domain EGF PF00008.27 EGB11368.1 - 0.012 15.9 37.3 0.92 9.9 0.5 4.7 4 1 1 5 5 5 0 EGF-like domain CDC50 PF03381.15 EGB11369.1 - 7.8e-68 229.0 0.1 1.3e-67 228.3 0.1 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family HD_5 PF13487.6 EGB11369.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 HD domain TPR_14 PF13428.6 EGB11370.1 - 0.0022 18.7 7.8 0.003 18.2 0.7 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11370.1 - 0.0039 17.2 2.2 5 7.5 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11370.1 - 0.0086 16.6 3.8 0.0086 16.6 3.8 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat COBRA1 PF06209.13 EGB11370.1 - 0.059 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) TPR_6 PF13174.6 EGB11370.1 - 0.21 12.3 7.2 0.93 10.3 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DAGAT PF03982.13 EGB11371.1 - 4.1e-54 183.5 0.0 4.5e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 EGB11371.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase DUF2826 PF11442.8 EGB11371.1 - 0.054 13.3 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) VCBS PF13517.6 EGB11373.1 - 1e-41 141.3 66.9 2.8e-11 43.8 4.7 5.4 2 2 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB11373.1 - 8.3e-25 86.6 58.1 0.00053 20.1 2.8 6.7 6 0 0 6 6 6 6 FG-GAP repeat BBS2_Mid PF14783.6 EGB11373.1 - 3.6e-08 33.4 0.0 4.4 7.4 0.0 5.9 6 0 0 6 6 6 2 Ciliary BBSome complex subunit 2, middle region BBS1 PF14779.6 EGB11373.1 - 1.8e-05 24.3 2.2 32 3.8 0.0 5.8 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 1 TcdB_toxin_midN PF12256.8 EGB11373.1 - 7e-05 22.3 22.5 0.14 11.5 0.1 6.1 3 1 3 6 6 6 6 Insecticide toxin TcdB middle/N-terminal region Itfg2 PF15907.5 EGB11373.1 - 0.0015 17.6 4.0 23 3.9 0.0 5.5 6 0 0 6 6 6 1 Integrin-alpha FG-GAP repeat-containing protein 2 Pkinase PF00069.25 EGB11375.1 - 2.3e-65 220.6 0.0 3e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11375.1 - 8e-30 104.0 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB11375.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB11375.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB11375.1 - 0.0082 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGB11375.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AAA PF00004.29 EGB11376.1 - 5.9e-05 23.5 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGB11376.1 - 0.0026 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EGB11376.1 - 0.025 14.9 0.0 0.079 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB11376.1 - 0.059 13.7 0.1 0.059 13.7 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 EGB11376.1 - 0.15 11.8 0.6 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGB11376.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Herpes_UL25 PF01499.16 EGB11376.1 - 8.8 4.7 12.8 3.9 5.9 7.0 2.3 1 1 1 2 2 2 0 Herpesvirus UL25 family Ku PF02735.16 EGB11377.1 - 1.1e-14 54.7 0.0 2.9e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain PH PF00169.29 EGB11377.1 - 3.4e-11 43.6 0.0 0.0011 19.4 0.0 3.4 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 EGB11377.1 - 0.00031 21.1 0.1 0.0034 17.8 0.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain SAP PF02037.27 EGB11377.1 - 0.0009 18.9 0.0 0.0028 17.4 0.0 1.9 2 0 0 2 2 2 1 SAP domain Glyco_trans_2_3 PF13632.6 EGB11377.1 - 0.0019 18.2 6.6 0.0035 17.3 6.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 PH_8 PF15409.6 EGB11377.1 - 0.0049 17.1 0.0 1.4 9.2 0.6 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain Chitin_synth_2 PF03142.15 EGB11377.1 - 0.0061 15.2 0.2 0.0091 14.7 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Tfb2 PF03849.14 EGB11379.1 - 2.7e-47 161.4 0.0 3.1e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EGB11379.1 - 3e-10 40.4 0.0 6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EGB11379.1 - 1.1e-05 25.6 2.0 2.5e-05 24.4 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Lactamase_B_2 PF12706.7 EGB11380.1 - 6.9e-16 58.4 0.3 4.1e-15 55.8 0.2 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGB11380.1 - 5.6e-08 33.0 0.8 1.8e-07 31.3 0.0 2.3 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Reprolysin_4 PF13583.6 EGB11380.1 - 9.4e-06 25.4 0.5 2.2e-05 24.2 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EGB11380.1 - 0.00018 21.7 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EGB11380.1 - 0.00038 21.0 0.0 0.001 19.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EGB11380.1 - 0.00072 19.5 0.2 0.0014 18.6 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EGB11380.1 - 0.14 11.1 7.4 0.03 13.3 3.8 1.6 2 0 0 2 2 2 0 Peptidase M66 ATP_bind_3 PF01171.20 EGB11381.1 - 4.5e-18 65.6 0.0 6.7e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 EGB11381.1 - 0.0022 17.2 0.0 0.003 16.7 0.0 1.1 1 0 0 1 1 1 1 NAD synthase PAPS_reduct PF01507.19 EGB11381.1 - 0.004 17.2 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glyco_tranf_2_3 PF13641.6 EGB11382.1 - 0.0049 16.8 0.3 0.011 15.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGB11382.1 - 0.049 13.4 0.1 0.34 10.7 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Phage_TAC_11 PF11836.8 EGB11382.1 - 0.2 11.8 0.0 0.2 11.8 0.0 3.4 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 ARL2_Bind_BART PF11527.8 EGB11383.1 - 1.2e-08 35.0 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART FCH PF00611.23 EGB11383.1 - 0.083 13.2 0.7 45 4.4 0.1 3.7 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain VIR_N PF15912.5 EGB11383.1 - 0.1 12.2 2.2 0.41 10.2 0.5 2.4 2 0 0 2 2 2 0 Virilizer, N-terminal Fib_alpha PF08702.10 EGB11383.1 - 0.15 12.3 4.3 1.8 8.8 0.1 3.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family PRIMA1 PF16101.5 EGB11383.1 - 2 8.5 13.1 1.3 9.1 5.8 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EGB11383.1 - 6.7 6.7 13.4 4.4 7.3 7.7 2.9 1 1 1 2 2 2 0 Mitochondrial fission regulator Glycos_transf_2 PF00535.26 EGB11384.1 - 1.1e-21 77.4 0.0 1.6e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB11384.1 - 9.1e-13 48.6 0.1 5.4e-12 46.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EGB11384.1 - 0.0016 18.9 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EGB11384.1 - 0.14 11.6 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 MGDG_synth PF06925.11 EGB11386.1 - 3.9e-24 85.7 0.0 5.2e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 EGB11386.1 - 1.3e-12 48.0 0.0 1.8e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 EGB11386.1 - 6.2e-06 26.7 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB11386.1 - 0.0003 20.4 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 DEAD PF00270.29 EGB11387.1 - 9e-38 129.8 0.1 1.6e-37 128.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11387.1 - 1.5e-24 86.5 0.3 2.2e-23 82.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB11387.1 - 8.1e-08 32.5 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGB11387.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit IBR PF01485.21 EGB11388.1 - 2.6e-17 62.8 29.2 1.1e-09 38.4 14.8 4.2 3 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGB11388.1 - 0.0078 16.0 6.6 0.0078 16.0 6.6 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SelR PF01641.18 EGB11389.1 - 2.8e-33 114.6 0.1 3.1e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EGB11389.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Prim_Zn_Ribbon PF08273.12 EGB11389.1 - 2 8.8 6.3 2 8.8 2.0 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase TRP PF06011.12 EGB11390.1 - 0.0042 15.9 12.7 0.0077 15.0 12.7 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel zf-C4_ClpX PF06689.13 EGB11390.1 - 0.074 13.0 1.4 0.21 11.5 1.4 1.8 1 0 0 1 1 1 0 ClpX C4-type zinc finger C1_2 PF03107.16 EGB11390.1 - 0.074 13.4 2.9 0.11 12.9 1.0 2.2 2 0 0 2 2 2 0 C1 domain CAP_N PF01213.19 EGB11390.1 - 0.59 9.6 18.6 0.73 9.2 6.4 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ArAE_2_N PF10337.9 EGB11391.1 - 0.52 9.3 1.8 0.96 8.4 1.8 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal MFS_1 PF07690.16 EGB11392.1 - 1.3e-05 24.4 41.0 1.3e-05 24.4 41.0 3.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Asp-B-Hydro_N PF05279.11 EGB11392.1 - 8.8 6.3 22.3 16 5.5 22.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF647 PF04884.14 EGB11393.1 - 5.3e-64 216.1 6.5 5.9e-64 216.0 6.5 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Ocnus PF05005.15 EGB11394.1 - 1.5e-23 82.9 0.0 3.2e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) NYN PF01936.18 EGB11395.1 - 6e-27 94.9 0.0 6.6e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 NYN domain PIN7 PF18475.1 EGB11395.1 - 0.0017 18.9 0.1 0.0055 17.3 0.1 1.8 1 1 0 1 1 1 1 PIN domain DUF5615 PF18480.1 EGB11395.1 - 0.02 14.7 0.1 0.058 13.2 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5615) FKBP_C PF00254.28 EGB11396.1 - 9.5e-32 109.2 0.0 1.2e-27 96.0 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EGB11396.1 - 9.5e-11 41.0 11.1 0.00045 20.1 1.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11396.1 - 8.4e-09 34.9 9.0 0.0007 19.3 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11396.1 - 2.2e-05 24.1 3.3 0.26 11.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11396.1 - 2.2e-05 24.6 6.3 0.0027 18.0 0.7 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11396.1 - 7.8e-05 23.1 3.4 0.38 11.5 0.3 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB11396.1 - 0.0025 17.4 4.0 2.3 8.0 0.1 3.4 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 EGB11396.1 - 0.0039 17.7 11.4 0.055 14.0 3.1 3.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11396.1 - 0.0087 16.7 14.6 0.034 14.8 2.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB11396.1 - 0.01 15.9 0.5 0.74 9.9 0.0 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EGB11396.1 - 0.011 16.4 11.3 0.18 12.7 1.8 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB11396.1 - 0.12 12.8 0.4 1.1 9.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGB11396.1 - 0.13 11.6 2.7 0.58 9.5 0.2 2.1 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_8 PF13181.6 EGB11396.1 - 0.47 10.8 3.9 2.1 8.7 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos PF00149.28 EGB11397.1 - 1.1e-23 84.8 2.4 2e-23 84.0 2.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 EGB11397.1 - 1e-12 46.7 2.6 0.00019 20.8 0.1 3.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EGB11397.1 - 1.7e-11 43.0 0.9 6.8e-05 22.2 0.5 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGB11397.1 - 2.2e-10 40.8 0.8 9.9e-10 38.7 0.8 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB11397.1 - 5.2e-10 39.0 2.3 0.00014 21.6 0.3 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB11397.1 - 6.1e-10 38.2 0.2 0.0014 18.4 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 EGB11397.1 - 0.0031 17.7 0.2 0.11 12.7 0.1 2.6 2 0 0 2 2 2 1 Dockerin type I domain zf-C2HC5 PF06221.13 EGB11398.1 - 0.28 11.2 0.2 0.28 11.2 0.2 2.2 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type Pkinase PF00069.25 EGB11400.1 - 1.7e-60 204.6 0.0 2e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11400.1 - 1.3e-29 103.3 0.0 1.6e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB11400.1 - 1.7e-07 30.8 0.1 0.00018 20.9 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Pkinase_C PF00433.24 EGB11400.1 - 6.1e-06 26.8 0.9 1.1e-05 26.0 0.9 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 EGB11400.1 - 0.00021 21.0 0.0 0.0058 16.3 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGB11400.1 - 0.0051 15.6 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGB11400.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB11400.1 - 0.064 12.2 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain AzlC PF03591.14 EGB11400.1 - 0.068 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AzlC protein Sel1 PF08238.12 EGB11401.1 - 1.5e-43 146.2 30.2 6.7e-10 39.3 1.1 8.2 8 2 0 8 8 8 7 Sel1 repeat TPR_1 PF00515.28 EGB11401.1 - 0.00023 20.8 0.4 0.0057 16.4 0.0 7.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB11401.1 - 0.0053 17.1 2.1 22 5.7 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF410 PF04190.13 EGB11401.1 - 0.019 14.7 1.1 1.1 8.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF410) PDDEXK_10 PF07788.11 EGB11401.1 - 0.024 14.6 0.5 9.1 6.3 0.0 2.9 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily TPR_12 PF13424.6 EGB11401.1 - 0.026 14.8 19.0 0.21 11.9 0.1 6.3 5 3 1 6 6 6 0 Tetratricopeptide repeat DUF4123 PF13503.6 EGB11401.1 - 0.032 14.7 0.0 4.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) TPR_10 PF13374.6 EGB11401.1 - 0.043 13.7 0.1 0.043 13.7 0.1 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11401.1 - 0.082 13.1 0.2 0.082 13.1 0.2 8.1 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11401.1 - 0.096 12.8 13.9 4.1 7.7 0.1 6.2 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGB11401.1 - 0.14 12.2 0.0 0.14 12.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Nuc_sug_transp PF04142.15 EGB11403.1 - 3.2e-53 180.9 1.8 5.1e-53 180.3 0.4 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter ABC_tran PF00005.27 EGB11403.1 - 1.7e-46 158.1 0.0 7.6e-25 88.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGB11403.1 - 6.1e-29 101.5 12.0 2.2e-19 70.2 1.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 EGB11403.1 - 6e-07 30.0 12.1 0.00029 21.3 0.2 4.5 3 2 1 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 EGB11403.1 - 1.3e-06 28.5 1.3 1.6 8.5 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB11403.1 - 3.8e-06 26.5 0.0 0.16 11.4 0.0 3.4 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGB11403.1 - 1.4e-05 25.1 0.2 0.21 11.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB11403.1 - 1.5e-05 24.9 0.3 0.093 12.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGB11403.1 - 1.9e-05 24.3 0.2 0.25 11.1 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB11403.1 - 2e-05 24.9 2.7 0.12 12.7 0.1 2.8 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 EGB11403.1 - 2.9e-05 23.3 0.4 0.037 13.1 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 EGB11403.1 - 3.2e-05 24.5 0.2 0.07 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGB11403.1 - 0.00018 21.7 0.1 0.37 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EGB11403.1 - 0.00024 21.2 0.3 0.5 10.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin family Zeta_toxin PF06414.12 EGB11403.1 - 0.0012 18.2 0.1 0.74 9.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.17 EGB11403.1 - 0.0014 18.8 1.0 0.3 11.2 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Mg_chelatase PF01078.21 EGB11403.1 - 0.0024 17.3 0.2 2.4 7.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGB11403.1 - 0.0025 17.4 0.2 2 7.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EGB11403.1 - 0.005 16.4 0.7 1.5 8.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB11403.1 - 0.0071 16.3 0.4 2.5 8.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain UAA PF08449.11 EGB11403.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 UAA transporter family RNA_helicase PF00910.22 EGB11403.1 - 0.011 16.1 0.1 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EGB11403.1 - 0.019 15.5 0.7 6.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGB11403.1 - 0.025 14.5 0.8 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 EGB11403.1 - 0.027 13.8 2.5 1.7 7.9 0.5 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 EGB11403.1 - 0.03 13.5 0.3 1.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGB11403.1 - 0.04 13.7 0.3 3.4 7.4 0.1 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 EGB11403.1 - 0.041 14.1 0.2 1.9 8.8 0.0 3.4 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EGB11403.1 - 0.087 13.3 0.7 0.96 9.9 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EGB11403.1 - 0.096 12.4 0.7 9.6 5.9 0.1 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 EGB11403.1 - 0.15 11.6 1.2 6.3 6.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 EGB11403.1 - 0.19 10.5 0.7 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 EGB11403.1 - 0.25 11.0 5.5 4.6 6.9 0.3 3.3 3 1 0 3 3 2 0 AAA domain SAT PF16073.5 EGB11403.1 - 4.7 6.9 6.7 32 4.1 0.0 2.6 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Rho_GDI PF02115.17 EGB11404.1 - 1.2e-43 149.1 0.0 1.4e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor FKBP_C PF00254.28 EGB11405.1 - 1.2e-19 70.4 0.0 1.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 EGB11405.1 - 1.2e-06 29.4 0.0 5.2e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YjhX_toxin PF09857.9 EGB11405.1 - 0.13 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair Sua5_yciO_yrdC PF01300.18 EGB11406.1 - 5.2e-35 120.6 0.0 6.6e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination Pro_isomerase PF00160.21 EGB11408.1 - 6.2e-50 169.5 0.0 7.7e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF5498 PF17602.2 EGB11408.1 - 0.0077 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5498) RRM_1 PF00076.22 EGB11409.1 - 1.7e-16 59.8 0.0 1.9e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EGB11409.1 - 4.6e-15 56.0 3.5 1e-14 54.9 3.5 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 EGB11409.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif MetallophosC PF16370.5 EGB11409.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 2 0 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Sel1 PF08238.12 EGB11410.1 - 1.2e-46 156.0 34.5 3.5e-09 37.0 0.9 8.7 8 2 0 8 8 8 8 Sel1 repeat AAA_lid_10 PF17872.1 EGB11410.1 - 0.0017 18.5 0.1 0.46 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA lid domain Prok-RING_4 PF14447.6 EGB11410.1 - 0.003 17.4 1.1 0.0051 16.7 1.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF977 PF06163.11 EGB11410.1 - 0.0097 15.9 1.4 0.18 11.8 0.1 3.1 2 1 0 3 3 3 1 Bacterial protein of unknown function (DUF977) Rubrerythrin PF02915.17 EGB11410.1 - 0.076 13.4 3.0 0.24 11.8 2.2 2.2 1 1 1 2 2 2 0 Rubrerythrin DUF4715 PF15835.5 EGB11410.1 - 0.082 13.0 0.3 0.82 9.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4715) zf-C3HC4_3 PF13920.6 EGB11410.1 - 0.084 12.7 2.0 0.15 11.9 2.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NSF PF02071.20 EGB11410.1 - 0.13 13.1 1.6 3e+02 3.0 0.0 4.9 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat B12-binding_2 PF02607.17 EGB11410.1 - 0.26 11.8 5.2 35 4.9 0.1 3.7 2 1 1 3 3 3 0 B12 binding domain DUF5522 PF17653.1 EGB11411.1 - 1.6e-21 76.0 2.0 3e-21 75.1 2.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 EGB11411.1 - 1.4e-10 41.1 0.0 2.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Diphthamide synthase Peripla_BP_2 PF01497.18 EGB11411.1 - 0.013 15.0 0.0 0.094 12.3 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein Oxidored-like PF09791.9 EGB11411.1 - 0.11 12.2 1.0 0.25 11.0 1.0 1.5 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal FeoB_associated PF12669.7 EGB11411.1 - 5.2 7.6 7.5 1.3 9.5 1.9 2.8 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Lipase_3 PF01764.25 EGB11412.1 - 3.6e-16 59.3 0.0 6.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 EGB11412.1 - 9.7e-10 38.4 18.8 7.8e-07 29.2 2.9 2.5 2 0 0 2 2 2 2 FYVE zinc finger Hydrolase_4 PF12146.8 EGB11412.1 - 0.092 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 IBR PF01485.21 EGB11412.1 - 0.21 11.8 7.6 0.81 10.0 0.8 3.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PGAP1 PF07819.13 EGB11412.1 - 0.29 10.8 0.0 0.46 10.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Zn-ribbon_8 PF09723.10 EGB11412.1 - 4.1 7.6 11.5 10 6.3 4.0 3.5 2 1 0 2 2 2 0 Zinc ribbon domain HpcH_HpaI PF03328.14 EGB11413.1 - 5.6e-35 120.5 0.2 6.5e-35 120.3 0.2 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family CoA_binding_2 PF13380.6 EGB11413.1 - 0.074 13.6 0.3 0.24 11.9 0.0 1.9 2 1 0 2 2 2 0 CoA binding domain Pkinase PF00069.25 EGB11414.1 - 7.5e-43 146.8 0.0 8.7e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11414.1 - 7.7e-22 77.8 0.0 1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB11414.1 - 2.3e-07 30.4 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB11414.1 - 5.8e-07 29.1 0.0 9.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB11414.1 - 1.5 8.7 14.7 0.017 15.1 5.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Calreticulin PF00262.18 EGB11415.1 - 3.8e-74 249.7 5.1 2e-51 175.0 0.2 2.2 1 1 1 2 2 2 2 Calreticulin family CDC45 PF02724.14 EGB11415.1 - 4.1 5.6 6.9 5.5 5.1 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CRAL_TRIO PF00650.20 EGB11416.1 - 1.4e-14 54.1 0.0 2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Nuc_sug_transp PF04142.15 EGB11417.1 - 2.1e-55 188.1 13.9 4.8e-55 186.9 13.9 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGB11417.1 - 1.3e-08 34.4 8.6 6.6e-08 32.1 8.6 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB11417.1 - 4.6e-08 33.3 23.9 8.4e-07 29.2 4.3 3.0 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EGB11417.1 - 1.3e-06 27.8 13.1 4e-06 26.3 13.1 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 EGB11417.1 - 0.00033 20.1 10.1 0.0052 16.2 10.4 2.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family DMT_6 PF04342.12 EGB11417.1 - 0.12 12.6 7.7 0.8 9.9 0.7 2.5 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) Phage_holin_5_2 PF16079.5 EGB11417.1 - 0.84 10.0 5.6 0.53 10.6 0.2 2.7 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V SLATT_4 PF18186.1 EGB11417.1 - 3.7 7.2 5.2 28 4.3 1.0 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 NARP1 PF12569.8 EGB11418.1 - 5.6e-114 381.9 23.7 1.7e-112 377.0 18.9 4.1 2 2 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 EGB11418.1 - 5e-11 41.9 4.6 1e-05 25.1 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11418.1 - 2.7e-09 36.4 13.5 2.6e-05 24.0 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB11418.1 - 5.2e-09 35.6 0.6 6.9e-08 32.0 0.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 EGB11418.1 - 3e-08 33.5 2.9 1.4 9.4 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11418.1 - 3.4e-07 30.0 2.9 0.0005 20.1 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB11418.1 - 0.0015 18.6 4.5 4 7.6 0.1 4.8 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EGB11418.1 - 0.0038 17.1 0.1 0.043 13.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB11418.1 - 0.0038 17.9 0.0 0.022 15.5 0.0 12.1 10 5 5 15 15 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB11418.1 - 0.004 17.3 16.7 0.1 12.8 0.1 5.9 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11418.1 - 0.021 15.4 4.3 2.5 8.9 0.1 5.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4228 PF14009.6 EGB11418.1 - 0.093 13.1 2.7 0.24 11.8 2.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) SRP-alpha_N PF04086.13 EGB11418.1 - 0.39 10.6 9.8 0.72 9.7 9.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Borrelia_P83 PF05262.11 EGB11418.1 - 7.6 4.9 17.2 13 4.1 17.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Sulfotransfer_4 PF17784.1 EGB11420.1 - 7.8e-13 48.7 0.0 2.6e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Maf PF02545.14 EGB11421.1 - 3.1e-55 186.5 0.0 3.5e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Ribosomal_L11_N PF03946.14 EGB11422.1 - 6.6e-26 89.9 0.3 9.1e-26 89.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGB11422.1 - 5.3e-23 81.3 0.0 7.8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NOA36 PF06524.12 EGB11422.1 - 0.42 9.9 5.0 0.5 9.6 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein Ion_trans PF00520.31 EGB11423.1 - 7.5e-10 38.4 9.7 8.4e-10 38.3 9.7 1.1 1 0 0 1 1 1 1 Ion transport protein GWT1 PF06423.12 EGB11423.1 - 0.63 10.1 3.6 0.56 10.3 2.1 1.6 1 1 0 1 1 1 0 GWT1 cNMP_binding PF00027.29 EGB11426.1 - 7.1e-17 61.3 0.2 8.3e-10 38.6 0.0 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain MBD PF01429.19 EGB11427.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain Glyco_transf_24 PF18404.1 EGB11429.1 - 1e-92 310.3 0.0 1.3e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_8 PF01501.20 EGB11429.1 - 2.8e-05 23.8 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 FH2 PF02181.23 EGB11430.1 - 4.2e-37 128.2 0.0 6e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 EGB11430.1 - 2.7e-32 112.3 6.6 4.8e-12 46.6 0.0 4.4 5 0 0 5 5 5 3 Subunit CCDC53 of WASH complex Drf_GBD PF06371.13 EGB11430.1 - 2.9e-10 40.0 0.0 9.6e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Laminin_G_3 PF13385.6 EGB11430.1 - 0.00012 22.3 0.3 0.00023 21.3 0.3 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sulfotransfer_1 PF00685.27 EGB11431.1 - 1.7e-20 73.6 0.0 3.1e-19 69.5 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB11431.1 - 0.00017 22.1 0.0 0.00073 20.0 0.0 2.0 1 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 EGB11431.1 - 0.091 12.6 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Sulfotransferase family PI-PLC-C1 PF16670.5 EGB11432.1 - 4e-43 147.8 0.0 2.3e-31 109.1 0.0 2.1 1 1 1 2 2 2 2 Phosphoinositide phospholipase C, Ca2+-dependent PI-PLC-X PF00388.19 EGB11432.1 - 0.037 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Mito_carr PF00153.27 EGB11433.1 - 2.7e-58 193.9 0.8 2.6e-21 75.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3_3 PF08239.11 EGB11434.1 - 0.008 16.4 0.0 0.039 14.2 0.0 2.0 1 1 0 1 1 1 1 Bacterial SH3 domain EF-hand_1 PF00036.32 EGB11435.1 - 5.9e-41 135.0 13.7 8e-10 37.6 1.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB11435.1 - 5.1e-35 119.8 3.0 7.7e-18 64.7 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB11435.1 - 1.7e-31 107.8 12.0 2.6e-16 59.2 0.8 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGB11435.1 - 5.6e-30 100.7 8.5 1.3e-09 37.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB11435.1 - 7.2e-27 91.7 9.9 2.3e-06 26.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGB11435.1 - 2.9e-15 56.4 0.2 2.5e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGB11435.1 - 4.9e-10 39.3 0.5 0.00012 22.0 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB11435.1 - 1.7e-08 34.8 0.0 0.0013 19.0 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGB11435.1 - 6.1e-07 30.3 0.0 0.00014 22.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 EGB11435.1 - 1.5e-05 25.0 0.3 0.13 12.3 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EGB11435.1 - 0.0001 22.3 1.3 0.0004 20.4 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 EGB11435.1 - 0.00038 20.6 4.0 0.034 14.3 0.3 2.9 1 1 2 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 EGB11435.1 - 0.0016 18.4 1.0 0.28 11.1 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EGB11435.1 - 0.0027 18.0 0.3 0.32 11.3 0.1 2.5 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 EGB11435.1 - 0.0029 17.5 0.3 0.66 9.9 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF3349 PF11829.8 EGB11435.1 - 0.0031 18.3 0.3 1.2 10.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF5580 PF17743.1 EGB11435.1 - 0.0066 15.1 0.0 0.0066 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF1103 PF06513.11 EGB11435.1 - 0.0067 16.1 1.3 0.0077 15.9 1.3 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF1296 PF06972.11 EGB11435.1 - 0.025 14.7 1.5 3.4 7.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) DUF853 PF05872.12 EGB11435.1 - 0.035 12.7 0.1 0.62 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 EGB11435.1 - 0.039 14.2 0.1 4.8 7.5 0.0 3.0 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SapB_1 PF05184.15 EGB11435.1 - 0.055 13.5 2.2 11 6.2 0.0 3.6 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF1456 PF07308.13 EGB11435.1 - 0.075 13.4 0.7 1.1 9.6 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_14 PF17959.1 EGB11435.1 - 0.076 13.4 0.2 10 6.5 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain MotA_activ PF09114.10 EGB11435.1 - 0.096 12.8 0.2 1.5 9.0 0.0 2.2 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Chloroa_b-bind PF00504.21 EGB11436.1 - 3.2e-28 99.3 0.0 5.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Aminotran_1_2 PF00155.21 EGB11437.1 - 1.3e-40 139.7 0.0 1.4e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGB11437.1 - 8.5e-07 28.6 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 EGB11437.1 - 0.00047 19.1 0.0 0.00062 18.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 EGB11437.1 - 0.00078 18.1 0.0 0.00095 17.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGB11437.1 - 0.0011 17.9 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGB11437.1 - 0.016 14.5 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase FAA_hydrolase PF01557.18 EGB11438.1 - 3.6e-52 177.2 0.0 5.4e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EGB11438.1 - 1.6e-23 82.9 0.0 2.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_3 PF13417.6 EGB11439.1 - 4.9e-07 30.1 0.0 8.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB11439.1 - 5.9e-07 29.4 0.5 2.4e-06 27.5 0.5 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGB11439.1 - 1.2e-06 28.6 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB11439.1 - 7.1e-05 23.0 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGB11439.1 - 0.0024 18.1 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGB11439.1 - 0.0039 17.5 0.0 0.0093 16.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Peptidase_C1 PF00112.23 EGB11440.1 - 1.9e-58 198.2 4.6 5.4e-58 196.6 4.6 1.6 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB11440.1 - 2.1e-05 23.5 0.8 0.0019 17.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DEAD PF00270.29 EGB11441.1 - 2.6e-14 53.4 0.0 2e-12 47.3 0.0 2.4 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11441.1 - 3.6e-06 27.3 0.0 6.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UVR PF02151.19 EGB11441.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif OB_NTP_bind PF07717.16 EGB11443.1 - 1.2e-11 44.8 0.0 3.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGB11443.1 - 1.1e-10 41.9 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EGB11443.1 - 1e-09 38.7 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EGB11443.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EGB11443.1 - 0.036 13.1 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EGB11443.1 - 0.037 13.8 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGB11443.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGB11443.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 EGB11443.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 EGB11443.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 EGB11443.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 EGB11443.1 - 0.13 12.5 0.3 0.64 10.3 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB11443.1 - 0.21 11.3 1.5 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGB11443.1 - 1.1 9.6 6.0 0.84 10.0 0.4 3.3 3 2 0 3 3 3 0 AAA ATPase domain Acyl_transf_1 PF00698.21 EGB11444.1 - 5.9e-21 75.3 1.0 4.9e-16 59.1 0.1 2.3 2 0 0 2 2 2 2 Acyl transferase domain TPR_12 PF13424.6 EGB11445.1 - 4.1e-12 46.2 4.3 0.0001 22.5 0.5 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11445.1 - 2.6e-06 27.0 4.3 0.17 11.7 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11445.1 - 8.3e-05 22.4 5.2 0.94 9.8 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11445.1 - 0.00015 22.2 4.2 0.073 13.6 0.7 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGB11445.1 - 0.00019 21.0 0.1 0.00027 20.4 0.1 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 EGB11445.1 - 0.0005 20.1 1.4 2.8 8.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11445.1 - 0.0027 17.5 3.5 9.9 6.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB11445.1 - 0.0074 17.0 0.3 8.6 7.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGB11445.1 - 0.0095 16.5 0.6 2.6 8.9 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGB11445.1 - 0.018 15.0 3.1 5.1 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB11445.1 - 0.048 14.1 0.9 2.6 8.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat WSS_VP PF12175.8 EGB11445.1 - 0.059 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP TPR_11 PF13414.6 EGB11445.1 - 0.063 13.0 1.6 6.9 6.4 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 EGB11445.1 - 0.069 13.8 6.3 4.4 8.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11445.1 - 0.19 12.4 1.8 35 5.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Chloroa_b-bind PF00504.21 EGB11447.1 - 8.1e-25 88.2 0.0 1.1e-24 87.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF563 PF04577.14 EGB11448.1 - 5.6e-09 36.4 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) ANAPC4_WD40 PF12894.7 EGB11448.1 - 2.4e-07 31.0 0.0 0.22 11.8 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGB11448.1 - 2.6e-06 28.0 0.0 0.63 11.0 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Exostosin PF03016.15 EGB11448.1 - 1.4e-05 24.4 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Exostosin family T2SSN PF01203.19 EGB11448.1 - 0.025 14.8 1.6 0.084 13.1 1.6 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein N PQQ_3 PF13570.6 EGB11448.1 - 0.21 12.1 5.4 26 5.5 0.2 4.8 3 0 0 3 3 3 0 PQQ-like domain tRNA_m1G_MT PF01746.21 EGB11449.1 - 8.3e-22 77.8 0.0 1.1e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ank_4 PF13637.6 EGB11450.1 - 1.8e-18 66.6 1.6 1.5e-10 41.4 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11450.1 - 4.1e-17 62.5 0.6 2.9e-16 59.8 0.6 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB11450.1 - 4.9e-16 58.6 6.5 3.9e-08 33.4 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB11450.1 - 3.4e-13 49.4 5.4 8.7e-07 29.1 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EGB11450.1 - 2.7e-11 42.7 0.8 0.0054 17.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Sel1 PF08238.12 EGB11451.1 - 3.1e-33 113.5 28.7 5e-09 36.5 0.1 7.9 6 2 0 6 6 6 6 Sel1 repeat TPR_12 PF13424.6 EGB11451.1 - 0.00016 21.9 14.6 0.018 15.3 1.4 4.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11451.1 - 0.0051 16.9 7.8 6.8 7.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF742 PF05331.11 EGB11451.1 - 0.017 14.9 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF742) TPR_16 PF13432.6 EGB11451.1 - 0.023 15.3 17.2 1.2 9.9 5.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGB11451.1 - 0.1 13.0 1.6 1.3 9.4 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11451.1 - 0.12 12.4 6.6 4.3 7.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11451.1 - 0.13 12.9 14.7 0.14 12.9 0.1 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat RHH_1 PF01402.21 EGB11451.1 - 0.37 10.8 5.4 12 6.0 0.1 3.3 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family TPR_10 PF13374.6 EGB11451.1 - 0.63 10.0 10.7 9.7 6.2 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat RMF PF04957.12 EGB11452.1 - 0.026 14.7 0.1 0.055 13.7 0.1 1.5 1 0 0 1 1 1 0 Ribosome modulation factor Thioredoxin PF00085.20 EGB11453.1 - 7.3e-24 83.7 0.0 7.8e-24 83.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB11453.1 - 4.5e-07 30.3 0.0 7e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGB11453.1 - 0.00027 21.2 0.0 0.065 13.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EGB11453.1 - 0.00028 20.8 0.0 0.00029 20.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EGB11453.1 - 0.0032 17.6 0.0 0.005 17.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EGB11453.1 - 0.0047 16.9 0.0 0.0056 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain DUF3235 PF11574.8 EGB11453.1 - 0.011 16.5 0.0 0.016 16.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) TraF PF13728.6 EGB11453.1 - 0.013 15.3 0.0 0.013 15.3 0.0 1.0 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EGB11453.1 - 0.059 13.1 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 EGB11453.1 - 0.065 12.9 0.0 0.065 12.9 0.0 1.2 1 1 0 1 1 1 0 Redoxin Neur_chan_LBD PF02931.23 EGB11454.1 - 1.7e-17 63.6 0.0 7.2e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Ank_2 PF12796.7 EGB11454.1 - 9.4e-17 61.4 1.8 4.4e-10 40.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB11454.1 - 5.1e-15 55.3 4.2 3e-05 24.2 0.1 4.1 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB11454.1 - 3.7e-14 52.9 1.3 1.3e-06 28.9 0.1 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11454.1 - 4.3e-12 45.1 0.7 0.039 14.5 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGB11454.1 - 7.3e-09 35.7 5.9 0.0052 17.2 0.1 5.0 4 0 0 4 4 4 2 Ankyrin repeat PIH1_CS PF18201.1 EGB11455.1 - 2.3e-07 31.2 0.0 3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain Mito_fiss_reg PF05308.11 EGB11455.1 - 0.15 12.1 1.4 0.19 11.8 1.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EGB11455.1 - 0.2 11.1 5.0 0.26 10.7 5.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TauE PF01925.19 EGB11456.1 - 2e-20 73.4 20.1 3.9e-20 72.5 20.1 1.4 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF962 PF06127.11 EGB11456.1 - 0.055 13.6 1.0 1.3 9.2 1.0 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF5381 PF17353.2 EGB11456.1 - 1.2 8.9 7.0 0.26 11.0 0.5 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5381) Mito_carr PF00153.27 EGB11457.1 - 2.1e-49 165.4 0.1 3e-16 59.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.12 EGB11458.1 - 9.9e-21 73.7 9.2 1.8e-20 72.8 9.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGB11458.1 - 4.4e-12 46.1 0.0 8.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGB11458.1 - 0.0014 18.0 0.8 0.0052 16.2 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 EGB11458.1 - 0.0075 15.6 0.3 0.014 14.7 0.3 1.4 1 0 0 1 1 1 1 ThiF family TOBE_2 PF08402.10 EGB11458.1 - 0.044 14.0 0.2 6.6 7.0 0.1 2.6 2 0 0 2 2 2 0 TOBE domain Sel1 PF08238.12 EGB11459.1 - 3.3e-25 87.9 28.2 2e-06 28.3 0.1 6.9 7 0 0 7 7 7 6 Sel1 repeat TPR_3 PF07720.12 EGB11459.1 - 0.053 13.5 1.2 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11459.1 - 0.16 11.9 7.7 5.5 7.0 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11459.1 - 1.8 9.3 13.0 9.4 7.1 0.5 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11459.1 - 4.4 7.8 9.3 4.2 7.8 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat HORMA PF02301.18 EGB11460.1 - 6.1e-10 39.0 0.0 2.6e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 HORMA domain FAD_binding_7 PF03441.14 EGB11461.1 - 5.5e-66 221.9 0.1 7.4e-66 221.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGB11461.1 - 4.4e-31 108.1 0.0 7.9e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase PI-PLC-X PF00388.19 EGB11462.1 - 5.8e-49 165.4 0.0 6.3e-49 165.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain TEP1_N PF05386.11 EGB11462.1 - 0.0073 15.9 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 TEP1 N-terminal domain BT1 PF03092.16 EGB11463.1 - 0.00012 20.4 0.3 0.00025 19.4 0.1 1.4 1 1 0 1 1 1 1 BT1 family Pyr_redox_2 PF07992.14 EGB11466.1 - 2.6e-48 164.7 0.1 3.8e-48 164.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGB11466.1 - 2e-26 92.4 0.0 5.1e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGB11466.1 - 9.2e-18 64.6 1.0 1.2e-14 54.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB11466.1 - 7.5e-07 28.2 1.4 0.0016 17.2 0.3 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 EGB11466.1 - 1.8e-06 27.5 3.6 0.014 14.7 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB11466.1 - 4.7e-06 25.9 1.1 0.00045 19.4 0.8 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGB11466.1 - 5.9e-06 26.4 1.5 0.071 13.4 0.3 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EGB11466.1 - 6.2e-06 25.7 0.1 0.0084 15.4 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGB11466.1 - 0.0004 19.9 0.3 0.013 14.9 0.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGB11466.1 - 0.0029 16.9 1.4 1.2 8.3 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EGB11466.1 - 0.0039 16.3 2.3 0.0077 15.4 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EGB11466.1 - 0.0072 15.4 1.2 0.91 8.5 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EGB11466.1 - 0.015 14.6 0.0 0.047 13.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 EGB11466.1 - 0.055 12.7 0.3 0.48 9.6 0.1 2.2 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 EGB11466.1 - 0.093 12.3 7.0 2.2 7.8 0.8 3.9 5 0 0 5 5 5 0 FAD dependent oxidoreductase XdhC_C PF13478.6 EGB11466.1 - 0.13 12.8 0.1 0.99 9.9 0.0 2.3 2 1 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 EGB11466.1 - 0.16 11.8 0.5 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L27 PF01016.19 EGB11467.1 - 2.8e-27 94.6 1.5 3e-27 94.5 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Ank_2 PF12796.7 EGB11468.1 - 4.4e-56 187.4 11.4 3.7e-11 43.4 0.0 9.5 5 4 6 11 11 11 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB11468.1 - 9.4e-45 150.1 35.5 5.1e-09 36.2 0.2 11.6 7 4 5 12 12 12 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB11468.1 - 1e-33 115.3 19.2 0.00018 22.0 0.0 10.7 9 1 0 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11468.1 - 4.6e-32 106.5 28.4 0.00042 20.6 0.0 15.7 18 0 0 18 18 18 6 Ankyrin repeat Ank PF00023.30 EGB11468.1 - 8.8e-20 70.2 43.7 0.00016 21.9 0.1 14.0 16 0 0 16 16 16 7 Ankyrin repeat VPS9 PF02204.18 EGB11468.1 - 8.1e-11 42.1 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain VASt PF16016.5 EGB11468.1 - 0.0039 17.6 0.0 0.0066 16.9 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Sina PF03145.16 EGB11469.1 - 8.1e-05 22.6 0.0 8.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4 PF00097.25 EGB11469.1 - 0.44 10.5 16.7 3.9 7.4 15.3 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB11469.1 - 0.47 10.3 21.4 2.3 8.1 19.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-WRNIP1_ubi PF18279.1 EGB11469.1 - 0.62 10.8 14.7 8.2 7.3 7.4 3.2 2 1 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_UBOX PF13445.6 EGB11469.1 - 0.76 9.9 14.7 7.9 6.6 13.0 2.5 1 1 1 2 2 2 0 RING-type zinc-finger MTP18 PF10558.9 EGB11470.1 - 7.2e-16 58.6 1.6 6.3e-09 36.0 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) PCMT PF01135.19 EGB11471.1 - 3.4e-28 98.8 0.0 4.6e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGB11471.1 - 5.3e-11 42.5 0.0 9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB11471.1 - 2.9e-07 31.1 0.1 6.3e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain zf-MYND PF01753.18 EGB11471.1 - 0.0009 19.3 4.8 0.0015 18.5 4.8 1.4 1 0 0 1 1 1 1 MYND finger Ubie_methyltran PF01209.18 EGB11471.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGB11471.1 - 0.019 15.6 0.8 0.076 13.7 0.8 2.1 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGB11471.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 EGB11471.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase cNMP_binding PF00027.29 EGB11473.1 - 7.3e-08 32.4 0.0 1.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ank_5 PF13857.6 EGB11474.1 - 6.7e-10 39.0 1.2 1.7e-05 25.0 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11474.1 - 5e-05 23.8 0.2 0.00012 22.6 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB11474.1 - 8.8e-05 23.0 0.1 0.0046 17.5 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB11474.1 - 0.0065 16.9 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EGB11474.1 - 0.0071 16.8 0.0 0.099 13.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Adeno_E4 PF05385.11 EGB11474.1 - 0.011 15.8 0.2 0.04 14.0 0.2 1.9 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Cpn10 PF00166.21 EGB11475.1 - 9.8e-22 76.8 0.0 1.1e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.21 EGB11476.1 - 5.7e-21 74.4 0.0 6.3e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Sel1 PF08238.12 EGB11477.1 - 1.3e-43 146.4 28.7 5.9e-09 36.3 0.1 7.8 8 0 0 8 8 8 7 Sel1 repeat TPR_17 PF13431.6 EGB11477.1 - 8.6e-05 22.6 3.3 4.8 7.8 0.0 5.4 4 1 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EGB11477.1 - 0.00056 19.9 20.8 0.011 15.8 1.1 4.8 6 0 0 6 6 6 2 MIT (microtubule interacting and transport) domain PDDEXK_10 PF07788.11 EGB11477.1 - 0.025 14.5 0.3 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Rubrerythrin PF02915.17 EGB11477.1 - 0.032 14.6 1.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Rubrerythrin TPR_12 PF13424.6 EGB11477.1 - 0.058 13.7 18.6 0.32 11.3 0.5 5.4 3 3 3 6 6 6 0 Tetratricopeptide repeat AAA_lid_10 PF17872.1 EGB11477.1 - 0.087 13.0 0.1 5.3 7.2 0.0 2.6 2 1 1 3 3 3 0 AAA lid domain Flu_M1_C PF08289.11 EGB11477.1 - 0.1 12.9 0.2 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Zn_dep_PLPC PF00882.18 EGB11477.1 - 0.11 12.5 0.0 8.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Zinc dependent phospholipase C B12-binding_2 PF02607.17 EGB11477.1 - 0.13 12.7 3.4 8.5 6.9 0.1 3.9 2 2 2 4 4 4 0 B12 binding domain TPR_8 PF13181.6 EGB11477.1 - 2.6 8.5 16.3 4.6 7.7 0.2 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat RRM_2 PF04059.12 EGB11478.1 - 8e-42 141.4 0.6 9.2e-42 141.2 0.6 1.0 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EGB11478.1 - 0.0049 16.7 0.7 0.032 14.1 0.4 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EGB11478.1 - 0.1 12.8 0.2 0.14 12.4 0.2 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 Pec_lyase_C PF00544.19 EGB11479.1 - 3.1e-26 92.3 4.3 1.2e-25 90.3 4.3 1.8 1 1 0 1 1 1 1 Pectate lyase PT PF04886.12 EGB11479.1 - 7.8e-09 34.9 52.0 1e-06 28.2 23.0 5.7 4 2 1 5 5 5 2 PT repeat Beta_helix PF13229.6 EGB11479.1 - 0.00015 21.6 0.1 0.00041 20.2 0.1 1.6 1 1 0 1 1 1 1 Right handed beta helix region CN_hydrolase PF00795.22 EGB11480.1 - 5.6e-48 163.6 0.0 6.8e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pro_Al_protease PF02983.14 EGB11480.1 - 0.32 11.1 5.1 0.15 12.2 0.5 2.8 3 0 0 3 3 3 0 Alpha-lytic protease prodomain DHHC PF01529.20 EGB11482.1 - 7.3e-37 126.5 5.9 1.2e-36 125.8 5.9 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase LRR_8 PF13855.6 EGB11483.1 - 2.1e-43 145.9 35.2 1.9e-11 43.6 0.6 7.8 3 2 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EGB11483.1 - 3.6e-36 122.6 33.1 4.3e-06 27.0 0.7 9.1 4 3 7 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB11483.1 - 6.6e-11 41.2 45.7 0.1 13.2 0.3 13.6 15 0 0 15 15 15 5 Leucine Rich Repeat LRR_9 PF14580.6 EGB11483.1 - 6.5e-10 38.8 15.4 0.0058 16.2 0.5 5.3 2 2 1 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 EGB11483.1 - 1.6e-05 24.5 36.9 8.1 6.8 0.2 11.9 13 0 0 13 13 13 5 Leucine Rich repeat UDPGP PF01704.18 EGB11484.1 - 1.4e-41 142.5 0.0 3.7e-41 141.1 0.0 1.5 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGB11484.1 - 0.0083 16.5 0.1 0.027 14.8 0.1 2.1 1 1 0 1 1 1 1 MobA-like NTP transferase domain PD40 PF07676.12 EGB11484.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EGB11486.1 - 1.5e-10 41.2 0.2 0.14 12.4 0.0 6.8 5 2 4 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EGB11486.1 - 6.8e-09 35.7 19.4 0.68 9.8 0.0 9.6 9 2 3 12 12 12 5 Region in Clathrin and VPS WD40 PF00400.32 EGB11486.1 - 9.7e-07 29.4 13.4 0.0018 19.1 0.0 6.2 6 0 0 6 6 6 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGB11486.1 - 0.00023 20.4 7.2 0.059 12.4 0.2 3.6 3 1 1 4 4 4 2 Coatomer WD associated region TPR_11 PF13414.6 EGB11486.1 - 0.038 13.7 2.3 35 4.2 0.0 5.4 5 0 0 5 5 5 0 TPR repeat eIF2A PF08662.11 EGB11486.1 - 0.046 13.6 0.0 1.6 8.6 0.0 3.2 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A RGS PF00615.19 EGB11486.1 - 0.12 12.7 2.7 0.57 10.5 0.2 3.1 3 0 0 3 3 3 0 Regulator of G protein signaling domain TPR_7 PF13176.6 EGB11486.1 - 3 8.1 22.1 1.1 9.5 0.2 9.3 11 1 0 11 11 11 0 Tetratricopeptide repeat DEAD PF00270.29 EGB11487.1 - 3.7e-40 137.6 0.0 5.1e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11487.1 - 6.9e-29 100.4 0.7 2.3e-28 98.8 0.5 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB11487.1 - 0.00012 22.2 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGB11487.1 - 0.0018 17.6 0.1 0.0026 17.0 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EGB11487.1 - 0.022 14.1 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DS PF01916.17 EGB11487.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase Chloroa_b-bind PF00504.21 EGB11488.1 - 1.7e-34 119.7 0.1 2.1e-34 119.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF3819 PF12842.7 EGB11489.1 - 3.3e-59 199.0 2.7 6.5e-59 198.1 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_CAF1_bind PF16415.5 EGB11489.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Cpn60_TCP1 PF00118.24 EGB11490.1 - 8.7e-143 476.5 12.4 9.9e-143 476.3 12.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DGF-1_5 PF11038.8 EGB11490.1 - 0.077 12.3 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 eRF1_2 PF03464.15 EGB11491.1 - 3.3e-44 150.4 0.0 5.2e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGB11491.1 - 4.7e-34 117.2 0.0 8.7e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 acVLRF1 PF18859.1 EGB11491.1 - 3.2e-09 37.2 0.1 5.1e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EGB11491.1 - 7.1e-07 29.6 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 eRF1_1 PF03463.15 EGB11491.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 1 Amino_oxidase PF01593.24 EGB11492.1 - 4e-11 42.9 0.0 5.8e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Methyltransf_3 PF01596.17 EGB11493.1 - 3e-57 193.2 0.0 3.6e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGB11493.1 - 1.2e-15 58.4 0.1 1.9e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB11493.1 - 1.1e-05 25.3 0.0 1.4e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EGB11493.1 - 0.0008 20.1 0.0 0.0013 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB11493.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB11493.1 - 0.015 15.9 0.3 0.065 13.9 0.2 2.1 2 1 0 2 2 2 0 Methyltransferase domain TauE PF01925.19 EGB11494.1 - 4.4e-20 72.3 20.6 8e-20 71.5 20.6 1.4 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Ribosomal_L24e PF01246.20 EGB11494.1 - 0.0048 17.1 0.1 0.016 15.4 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L24e DUF5381 PF17353.2 EGB11494.1 - 1.5 8.6 7.7 0.21 11.3 0.6 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5381) Chloroa_b-bind PF00504.21 EGB11495.1 - 4.3e-30 105.4 0.0 9.4e-30 104.3 0.0 1.5 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Methyltransf_24 PF13578.6 EGB11497.1 - 0.0007 20.6 3.1 0.001 20.0 0.1 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB11497.1 - 0.031 15.0 0.0 0.17 12.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Pkinase_Tyr PF07714.17 EGB11498.1 - 7e-48 163.2 0.0 7.6e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGB11498.1 - 4.2e-42 144.3 0.0 5.1e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGB11498.1 - 0.0003 19.7 0.0 0.00082 18.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGB11498.1 - 0.032 14.1 0.2 0.27 11.1 0.2 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_10 PF13460.6 EGB11499.1 - 9.3e-23 81.1 0.0 1.6e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGB11499.1 - 3.7e-13 49.6 0.0 5.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGB11499.1 - 2.8e-10 40.1 0.1 6.5e-10 38.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB11499.1 - 0.0012 17.9 0.2 0.002 17.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGB11499.1 - 0.003 16.7 0.1 0.006 15.7 0.1 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 EGB11499.1 - 0.031 14.5 1.2 0.1 12.9 0.2 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EGB11499.1 - 0.047 13.1 0.5 0.081 12.4 0.5 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 EGB11499.1 - 0.048 13.8 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RVT_3 PF13456.6 EGB11499.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like GDP_Man_Dehyd PF16363.5 EGB11499.1 - 0.15 11.4 0.4 0.45 9.9 0.1 2.0 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EGB11499.1 - 0.26 11.7 0.9 0.78 10.2 0.9 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pro_isomerase PF00160.21 EGB11500.1 - 3.8e-48 163.7 0.0 4.4e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGB11501.1 - 1.6e-07 31.0 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGB11501.1 - 0.0098 15.9 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Limkain b1 GRP PF07172.11 EGB11501.1 - 3.3 8.5 27.3 10 6.9 20.0 2.6 2 0 0 2 2 2 0 Glycine rich protein family Ras PF00071.22 EGB11505.1 - 4.7e-49 166.1 0.0 5.7e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB11505.1 - 2.3e-30 105.3 0.0 6.3e-30 103.9 0.0 1.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB11505.1 - 1.2e-09 37.9 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB11505.1 - 9.7e-05 22.4 0.0 0.00027 21.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGB11505.1 - 0.00051 20.4 0.1 0.0028 18.0 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EGB11505.1 - 0.0029 17.0 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ArgoMid PF16487.5 EGB11505.1 - 0.016 15.4 0.1 0.033 14.5 0.1 1.5 1 0 0 1 1 1 0 Mid domain of argonaute Septin PF00735.18 EGB11505.1 - 0.033 13.5 0.1 0.067 12.5 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 EGB11505.1 - 0.037 13.7 0.0 0.064 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGB11505.1 - 0.065 12.7 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.12 EGB11505.1 - 0.067 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.6 EGB11505.1 - 0.068 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGB11505.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EGB11505.1 - 0.084 12.8 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 EGB11505.1 - 0.094 11.9 2.3 2.4 7.2 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.6 EGB11505.1 - 0.14 12.3 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB11505.1 - 0.17 11.9 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SET PF00856.28 EGB11506.1 - 0.00093 19.6 0.0 0.0027 18.1 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF2236 PF09995.9 EGB11507.1 - 2.5e-41 142.4 2.1 2.5e-41 142.4 2.1 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Sulfatase PF00884.23 EGB11508.1 - 7.8e-35 120.8 0.0 8.7e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Sulfatase TPR_2 PF07719.17 EGB11509.1 - 0.00021 21.1 11.3 0.0022 18.0 0.9 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11509.1 - 0.00036 21.0 3.7 0.00036 21.0 3.7 3.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11509.1 - 0.0012 18.6 0.5 0.17 11.8 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGB11509.1 - 0.0012 18.4 2.6 0.49 10.1 0.0 2.4 1 1 1 2 2 2 2 TPR repeat BTAD PF03704.17 EGB11509.1 - 0.011 16.2 0.2 0.011 16.2 0.2 3.2 1 1 2 3 3 3 0 Bacterial transcriptional activator domain TPR_8 PF13181.6 EGB11509.1 - 0.021 15.0 0.7 5.2 7.6 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB11509.1 - 0.032 15.1 3.9 0.032 15.1 3.9 4.7 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB11509.1 - 0.23 11.6 10.5 0.086 13.0 1.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat 5_nucleotid_C PF02872.18 EGB11510.1 - 4.2e-33 114.8 0.0 8.3e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGB11510.1 - 1.2e-06 29.2 0.7 2.9e-06 28.0 0.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ApbA_C PF08546.11 EGB11511.1 - 0.0027 17.9 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal CHB_HEX_C_1 PF13290.6 EGB11512.1 - 0.00054 19.9 0.2 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EGB11512.1 - 0.05 13.8 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 Fn3 associated DUF3606 PF12244.8 EGB11512.1 - 0.14 12.1 0.0 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) PDZ PF00595.24 EGB11513.1 - 0.15 12.5 0.0 0.46 10.9 0.0 1.9 1 0 0 1 1 1 0 PDZ domain Sel1 PF08238.12 EGB11514.1 - 3.6e-20 72.0 15.8 2.8e-06 27.8 0.6 4.3 4 0 0 4 4 4 4 Sel1 repeat TPR_16 PF13432.6 EGB11514.1 - 0.0062 17.2 9.9 0.018 15.7 2.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11514.1 - 0.0072 16.6 0.6 0.0072 16.6 0.6 3.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11514.1 - 0.035 14.0 0.2 0.035 14.0 0.2 4.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11514.1 - 0.053 13.6 1.0 0.053 13.6 1.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF977 PF06163.11 EGB11514.1 - 0.15 12.0 0.1 0.65 10.0 0.0 1.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF977) TPR_10 PF13374.6 EGB11514.1 - 2.5 8.1 6.4 1.5 8.8 0.2 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Ephrin_rec_like PF07699.13 EGB11516.1 - 1.4e-34 117.6 78.2 4.5e-06 26.3 3.5 10.3 4 2 6 10 10 10 10 Putative ephrin-receptor like NCD3G PF07562.14 EGB11516.1 - 1.1e-05 25.3 50.7 1.1 9.3 0.4 9.2 7 1 1 9 9 9 8 Nine Cysteines Domain of family 3 GPCR VSP PF03302.13 EGB11516.1 - 0.12 11.2 78.9 0.39 9.5 21.9 4.3 1 1 4 5 5 5 0 Giardia variant-specific surface protein TNFR_c6 PF00020.18 EGB11516.1 - 0.83 10.1 58.3 1.4 9.4 2.7 10.6 5 1 4 10 10 10 0 TNFR/NGFR cysteine-rich region YhfH PF14149.6 EGB11516.1 - 1 9.4 0.0 1 9.4 0.0 4.3 7 0 0 7 7 7 0 YhfH-like protein SH3_1 PF00018.28 EGB11517.1 - 2.5e-13 49.4 0.1 4e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGB11517.1 - 8.9e-12 44.7 0.2 1.9e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGB11517.1 - 8.1e-09 35.0 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_7 PF13499.6 EGB11518.1 - 5.2e-18 65.3 0.0 1.3e-13 51.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB11518.1 - 1.4e-17 62.1 0.3 2.3e-06 27.1 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGB11518.1 - 4.1e-17 60.4 0.0 1e-05 24.7 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 EGB11518.1 - 5.7e-11 41.4 0.1 0.0002 20.7 0.0 3.3 3 0 0 3 3 3 3 EF hand Dockerin_1 PF00404.18 EGB11518.1 - 4.9e-07 29.8 5.8 0.00055 20.1 2.3 2.2 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_8 PF13833.6 EGB11518.1 - 1.6e-06 27.9 0.4 0.00013 21.8 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB11518.1 - 0.00017 21.9 0.1 0.00046 20.5 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain DUF2789 PF10982.8 EGB11518.1 - 0.0024 18.0 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2789) Caleosin PF05042.13 EGB11518.1 - 0.091 12.7 0.1 13 5.7 0.0 2.3 2 1 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGB11518.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region LNS2 PF08235.13 EGB11518.1 - 0.11 12.0 0.0 0.86 9.0 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) SNF2_N PF00176.23 EGB11519.1 - 1.2e-33 116.3 0.0 1.3e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGB11519.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11520.1 - 6.3e-07 29.7 0.0 1.7e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_4 PF13871.6 EGB11520.1 - 0.06 13.0 0.1 0.063 13.0 0.1 1.0 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue Mntp PF02659.15 EGB11521.1 - 5.4e-05 23.0 6.9 0.045 13.5 1.6 2.3 2 0 0 2 2 2 2 Putative manganese efflux pump Dscam_C PF12355.8 EGB11521.1 - 3.6 8.6 10.8 3 8.8 1.6 2.6 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal HgmA PF04209.13 EGB11523.1 - 3.4e-154 513.6 0.0 3.9e-154 513.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AraC_binding PF02311.19 EGB11523.1 - 0.084 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Retrotran_gag_2 PF14223.6 EGB11524.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type EF-hand_1 PF00036.32 EGB11525.1 - 5.9e-41 135.0 13.7 8e-10 37.6 1.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB11525.1 - 5.1e-35 119.8 3.0 7.7e-18 64.7 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB11525.1 - 1.7e-31 107.8 12.0 2.6e-16 59.2 0.8 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGB11525.1 - 5.6e-30 100.7 8.5 1.3e-09 37.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB11525.1 - 7.2e-27 91.7 9.9 2.3e-06 26.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGB11525.1 - 2.9e-15 56.4 0.2 2.5e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGB11525.1 - 4.9e-10 39.3 0.5 0.00012 22.0 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB11525.1 - 1.7e-08 34.8 0.0 0.0013 19.0 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGB11525.1 - 6.1e-07 30.3 0.0 0.00014 22.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 EGB11525.1 - 1.5e-05 25.0 0.3 0.13 12.3 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EGB11525.1 - 0.0001 22.3 1.3 0.0004 20.4 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 EGB11525.1 - 0.00038 20.6 4.0 0.034 14.3 0.3 2.9 1 1 2 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 EGB11525.1 - 0.0016 18.4 1.0 0.28 11.1 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EGB11525.1 - 0.0027 18.0 0.3 0.32 11.3 0.1 2.5 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 EGB11525.1 - 0.0029 17.5 0.3 0.66 9.9 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF3349 PF11829.8 EGB11525.1 - 0.0031 18.3 0.3 1.2 10.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF5580 PF17743.1 EGB11525.1 - 0.0066 15.1 0.0 0.0066 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF1103 PF06513.11 EGB11525.1 - 0.0067 16.1 1.3 0.0077 15.9 1.3 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF1296 PF06972.11 EGB11525.1 - 0.025 14.7 1.5 3.4 7.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) DUF853 PF05872.12 EGB11525.1 - 0.035 12.7 0.1 0.62 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 EGB11525.1 - 0.039 14.2 0.1 4.8 7.5 0.0 3.0 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SapB_1 PF05184.15 EGB11525.1 - 0.055 13.5 2.2 11 6.2 0.0 3.6 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF1456 PF07308.13 EGB11525.1 - 0.075 13.4 0.7 1.1 9.6 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_14 PF17959.1 EGB11525.1 - 0.076 13.4 0.2 10 6.5 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain MotA_activ PF09114.10 EGB11525.1 - 0.096 12.8 0.2 1.5 9.0 0.0 2.2 1 1 0 2 2 2 0 Transcription factor MotA, activation domain MSP PF01716.18 EGB11526.1 - 1.4e-91 306.0 1.3 1.6e-91 305.8 1.3 1.0 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide PhyH PF05721.13 EGB11527.1 - 0.00021 21.6 0.0 0.00087 19.6 0.0 2.1 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) HA PF03457.14 EGB11527.1 - 0.18 12.2 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 Helicase associated domain Glyco_trans_1_2 PF13524.6 EGB11528.1 - 4.6e-07 30.1 0.1 1.4e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 EGB11529.1 - 1.4e-18 67.2 0.0 2.6e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11529.1 - 1.6e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4201 PF13870.6 EGB11529.1 - 0.0038 17.0 5.6 0.0088 15.8 5.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Pkinase_fungal PF17667.1 EGB11529.1 - 0.014 14.2 0.2 0.088 11.6 0.0 2.1 1 1 1 2 2 2 0 Fungal protein kinase EzrA PF06160.12 EGB11529.1 - 0.047 11.9 4.9 0.079 11.1 4.9 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sulfotransfer_3 PF13469.6 EGB11530.1 - 1.1e-08 35.8 0.2 4.9e-05 23.8 0.1 3.6 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB11530.1 - 2.1e-07 30.7 0.0 5e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_2 PF03567.14 EGB11530.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family Kelch_3 PF13415.6 EGB11531.1 - 3.8e-26 90.8 17.6 1.9e-05 24.8 0.1 7.1 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGB11531.1 - 9.4e-18 64.0 10.3 0.00089 19.2 0.8 7.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGB11531.1 - 3.8e-14 52.4 4.6 0.086 13.2 0.0 6.8 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGB11531.1 - 9.7e-12 44.3 3.0 0.096 12.3 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EGB11531.1 - 2.1e-09 37.0 1.8 0.041 13.9 0.1 5.9 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EGB11531.1 - 2.6e-05 24.1 10.5 0.43 10.6 0.0 6.5 7 1 0 7 7 7 2 Kelch motif DUF973 PF06157.11 EGB11532.1 - 0.0082 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) DUF973 PF06157.11 EGB11533.1 - 0.0077 15.3 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) WW PF00397.26 EGB11534.1 - 1.4e-21 76.2 13.1 8e-11 41.8 2.7 2.6 2 0 0 2 2 2 2 WW domain SH3_9 PF14604.6 EGB11534.1 - 4.1e-09 36.2 0.0 7.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PQQ PF01011.21 EGB11534.1 - 9e-06 25.4 0.1 0.21 11.6 0.0 2.8 2 0 0 2 2 2 2 PQQ enzyme repeat SH3_1 PF00018.28 EGB11534.1 - 0.00011 21.7 0.0 0.00043 19.8 0.0 2.0 1 1 0 1 1 1 1 SH3 domain Ntox37 PF15535.6 EGB11534.1 - 0.0032 17.8 3.6 1.2 9.7 0.2 2.8 2 0 0 2 2 2 2 Bacterial toxin 37 DUF2782 PF11191.8 EGB11534.1 - 0.04 14.1 0.1 16 5.7 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) Glyco_hyd_101C PF17451.2 EGB11534.1 - 0.053 13.8 1.3 4 7.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain MHC_II_alpha PF00993.20 EGB11534.1 - 0.17 11.6 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain GST_N_3 PF13417.6 EGB11535.1 - 4.4e-12 46.2 0.0 7.9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB11535.1 - 2.9e-09 37.1 0.0 5.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EGB11535.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 EGB11535.1 - 0.0038 17.9 0.0 0.024 15.4 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain DUF953 PF06110.11 EGB11535.1 - 0.07 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) GST_N_3 PF13417.6 EGB11536.1 - 1.9e-12 47.4 0.0 7.7e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB11536.1 - 3e-09 37.0 0.0 5.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB11536.1 - 9e-07 28.8 1.8 2.2e-06 27.6 1.6 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB11536.1 - 3.7e-06 27.1 0.0 5.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGB11536.1 - 7.1e-06 26.1 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGB11536.1 - 0.00014 22.4 0.0 0.00022 21.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGB11536.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_N_4 PF17172.4 EGB11536.1 - 0.003 18.3 0.0 0.018 15.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain DUF953 PF06110.11 EGB11536.1 - 0.077 12.6 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Methyltransf_5 PF01795.19 EGB11537.1 - 1.9e-66 224.7 0.0 3.5e-66 223.8 0.0 1.4 1 1 0 1 1 1 1 MraW methylase family CNDH2_C PF16858.5 EGB11539.1 - 6.1e-32 111.7 0.0 1.2e-31 110.7 0.0 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 EGB11539.1 - 7.6e-22 77.7 0.0 1.3e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Arylsulfotrans PF05935.11 EGB11539.1 - 3.5e-09 36.0 0.0 6.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) CENP-X PF09415.10 EGB11539.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Cnd2 PF05786.14 EGB11539.1 - 1.4 7.5 6.0 0.076 11.7 0.2 1.8 2 0 0 2 2 2 0 Condensin complex subunit 2 EF-hand_7 PF13499.6 EGB11540.1 - 0.00029 21.2 0.4 0.0015 18.9 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain pair CDC27 PF09507.10 EGB11540.1 - 0.055 12.8 29.4 0.088 12.2 29.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ASFV_J13L PF05568.11 EGB11540.1 - 4.8 6.9 7.4 11 5.8 7.4 1.7 1 0 0 1 1 1 0 African swine fever virus J13L protein Ribosomal_S17_N PF16205.5 EGB11541.1 - 1.4e-32 111.9 0.3 2.5e-32 111.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGB11541.1 - 2.8e-25 88.2 1.2 8.2e-25 86.7 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 DUSP PF06337.12 EGB11542.1 - 0.15 12.7 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 DUSP domain Chloroa_b-bind PF00504.21 EGB11543.1 - 1.6e-29 103.5 0.1 2.1e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pkinase PF00069.25 EGB11544.1 - 8.9e-59 199.0 0.0 1e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11544.1 - 7.2e-33 113.9 0.0 8.6e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB11544.1 - 4.8e-06 26.1 0.0 9.2e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGB11544.1 - 2.2e-05 24.5 3.8 0.024 14.5 0.6 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB11544.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGB11544.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyanate_lyase PF02560.14 EGB11545.1 - 3e-29 100.7 0.2 5e-29 100.0 0.2 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EGB11545.1 - 0.11 12.8 0.1 0.24 11.8 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain TTL PF03133.15 EGB11547.1 - 3.1e-10 39.7 0.0 6.9e-10 38.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family Aminotran_5 PF00266.19 EGB11548.1 - 3.8e-10 39.3 0.0 1.4e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Glycos_transf_N PF04413.16 EGB11548.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) AA_permease PF00324.21 EGB11549.1 - 2.4e-54 184.7 18.6 3.1e-54 184.3 18.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF543 PF04418.12 EGB11549.1 - 0.87 9.6 4.4 7.7 6.6 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Phage_holin_3_1 PF05106.12 EGB11549.1 - 3.8 8.0 8.9 2.5 8.6 0.1 3.3 3 1 0 3 3 3 0 Phage holin family (Lysis protein S) PGI PF00342.19 EGB11550.1 - 2.3e-180 600.4 0.0 3.1e-180 599.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase RTP1_C2 PF10304.9 EGB11550.1 - 0.25 11.1 1.1 0.74 9.6 0.3 2.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Glyco_hydro_45 PF02015.16 EGB11551.1 - 1.2e-32 113.6 9.4 1.4e-32 113.3 9.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 TPR_2 PF07719.17 EGB11552.1 - 2.8e-37 123.8 12.9 6.1e-05 22.8 0.4 9.5 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11552.1 - 1.4e-35 119.6 15.4 3.7e-05 23.4 0.0 8.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11552.1 - 9.1e-27 91.0 7.3 0.00053 20.0 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGB11552.1 - 5.8e-26 89.9 3.6 3.3e-08 33.1 0.0 7.8 5 1 3 8 8 8 6 TPR repeat TPR_12 PF13424.6 EGB11552.1 - 1.5e-23 82.9 17.1 4e-08 33.4 0.4 7.4 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11552.1 - 8.4e-21 74.3 0.2 0.0015 19.2 0.0 6.4 5 1 1 6 6 6 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB11552.1 - 6.4e-18 64.8 6.8 0.00012 22.2 0.2 5.4 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGB11552.1 - 1e-17 62.7 1.2 0.0011 18.8 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB11552.1 - 7e-17 60.7 2.4 3e-05 24.5 0.0 7.9 4 2 4 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB11552.1 - 9.8e-13 48.1 0.2 0.0025 17.9 0.0 5.5 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11552.1 - 3.7e-11 43.4 10.8 0.0027 18.2 0.0 6.9 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB11552.1 - 4.2e-11 42.4 19.2 0.0036 17.6 0.0 8.4 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11552.1 - 4.9e-11 42.1 8.1 0.0028 17.5 0.0 8.0 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11552.1 - 5.9e-11 42.3 7.9 0.19 12.5 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGB11552.1 - 2.7e-09 36.7 3.8 0.00033 19.9 0.0 4.7 2 2 1 3 3 3 2 Tetratricopeptide repeat PknG_TPR PF16918.5 EGB11552.1 - 1.7e-05 23.7 0.1 0.00068 18.5 0.0 2.5 2 1 1 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_3 PF07720.12 EGB11552.1 - 0.00056 19.9 7.1 9.1 6.4 0.2 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EGB11552.1 - 0.00087 19.7 1.7 0.88 10.0 0.1 3.1 4 0 0 4 4 2 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EGB11552.1 - 0.0019 17.6 1.6 1.1 8.6 0.0 3.6 2 1 1 3 3 3 1 MalT-like TPR region Coatomer_E PF04733.14 EGB11552.1 - 0.005 16.3 0.2 0.066 12.6 0.0 2.4 3 0 0 3 3 3 1 Coatomer epsilon subunit Vps39_1 PF10366.9 EGB11552.1 - 0.0081 16.4 0.8 5.7 7.3 0.0 3.7 2 2 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 SNAP PF14938.6 EGB11552.1 - 0.016 14.7 0.8 0.075 12.4 0.0 2.4 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 EGB11552.1 - 0.019 15.0 2.1 2.5 8.2 0.0 4.7 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Wzy_C_2 PF11846.8 EGB11552.1 - 0.041 13.8 1.1 28 4.6 0.0 3.4 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_21 PF09976.9 EGB11552.1 - 0.056 13.1 1.7 2.7 7.6 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 EGB11552.1 - 0.14 12.3 7.8 3.9 7.6 0.0 4.5 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat DUF5113 PF17140.4 EGB11552.1 - 0.41 10.4 4.3 12 5.6 1.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) Pyrid_oxidase_2 PF13883.6 EGB11553.1 - 5e-13 49.4 0.0 1.3e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 EGB11553.1 - 1.7e-06 28.6 0.1 4.4e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) LacI PF00356.21 EGB11553.1 - 0.046 13.5 0.3 0.15 11.9 0.3 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family NAD_binding_8 PF13450.6 EGB11554.1 - 1.8e-09 37.7 1.2 1.8e-09 37.7 1.2 3.6 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGB11554.1 - 1.1e-05 25.0 5.0 5e-05 22.8 0.7 2.8 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGB11554.1 - 9.8e-05 22.1 5.9 0.00027 20.7 2.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB11554.1 - 0.018 15.6 1.6 0.059 13.9 1.6 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGB11554.1 - 0.023 14.7 1.2 0.096 12.7 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pam16 PF03656.13 EGB11554.1 - 0.21 11.6 1.9 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 Pam16 Aa_trans PF01490.18 EGB11555.1 - 2e-47 161.8 1.6 3e-47 161.3 1.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC1 PF03109.16 EGB11555.1 - 8.4e-14 51.8 0.0 1.9e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Med26 PF08711.11 EGB11555.1 - 6.7e-07 29.2 3.2 9.3e-07 28.8 0.8 2.6 2 0 0 2 2 2 1 TFIIS helical bundle-like domain HMG_box PF00505.19 EGB11555.1 - 0.00014 22.2 0.3 0.0018 18.6 0.2 2.8 2 0 0 2 2 2 1 HMG (high mobility group) box LMBR1 PF04791.16 EGB11555.1 - 1 8.2 6.4 2.4 7.0 6.4 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Podoplanin PF05808.11 EGB11556.1 - 0.00014 22.0 0.8 0.00027 21.1 0.8 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EGB11556.1 - 0.0064 16.4 0.1 0.017 15.0 0.1 1.6 2 0 0 2 2 2 1 TMEM154 protein family DUF4690 PF15756.5 EGB11556.1 - 0.021 15.4 3.7 0.04 14.5 3.7 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage VSP PF03302.13 EGB11556.1 - 0.07 12.0 0.3 0.1 11.4 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein ASFV_J13L PF05568.11 EGB11556.1 - 0.089 12.5 0.2 0.089 12.5 0.2 2.4 2 1 1 3 3 3 0 African swine fever virus J13L protein AJAP1_PANP_C PF15298.6 EGB11556.1 - 0.21 11.8 2.2 0.38 10.9 2.2 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.17 EGB11556.1 - 0.24 11.4 9.6 0.5 10.3 9.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3586 PF12131.8 EGB11556.1 - 0.34 11.2 2.8 0.81 9.9 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) MGC-24 PF05283.11 EGB11556.1 - 0.47 10.9 1.3 1.2 9.6 1.3 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adeno_E3_CR2 PF02439.15 EGB11556.1 - 2.5 7.9 7.1 4.7 7.0 7.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DHC_N1 PF08385.12 EGB11557.1 - 1.6e-164 548.6 0.6 3.3e-162 541.0 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EGB11557.1 - 1.2e-140 468.2 0.0 5.3e-78 262.3 0.0 4.0 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB11557.1 - 3.4e-115 385.3 0.9 3.4e-115 385.3 0.9 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGB11557.1 - 2.3e-97 325.4 0.0 6.4e-97 323.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGB11557.1 - 1.3e-78 264.4 0.0 3.5e-78 262.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGB11557.1 - 4.5e-78 261.4 0.0 1.2e-77 260.0 0.0 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 EGB11557.1 - 6.2e-71 239.2 14.0 1.4e-70 238.0 14.0 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 EGB11557.1 - 2.6e-69 232.3 0.0 2.9e-63 212.6 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB11557.1 - 5.9e-42 143.3 0.0 2.3e-41 141.3 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB11557.1 - 1.2e-36 125.4 0.0 1.3e-35 122.1 0.0 3.0 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 EGB11557.1 - 3.7e-28 97.7 0.1 2.7e-26 91.7 0.0 3.3 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EGB11557.1 - 7.1e-21 74.6 0.0 2.3e-20 73.0 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGB11557.1 - 1.8e-20 73.3 0.0 4.4e-06 26.7 0.0 5.7 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB11557.1 - 2.4e-09 37.6 0.7 0.14 12.5 0.0 5.6 6 0 0 6 6 4 2 AAA domain AAA_16 PF13191.6 EGB11557.1 - 3.7e-09 37.2 0.2 0.0045 17.4 0.0 5.4 4 0 0 4 4 4 1 AAA ATPase domain AAA PF00004.29 EGB11557.1 - 8.4e-08 32.7 1.0 0.44 11.0 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGB11557.1 - 3.9e-06 27.1 1.5 0.19 11.9 0.0 4.7 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.6 EGB11557.1 - 1.7e-05 25.4 0.0 1.3 9.6 0.0 4.6 4 0 0 4 4 4 2 AAA domain Sigma54_activat PF00158.26 EGB11557.1 - 2.7e-05 23.9 0.0 0.13 11.9 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 EGB11557.1 - 3.5e-05 23.8 0.4 1.4 8.9 0.0 3.8 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EGB11557.1 - 7.7e-05 22.9 0.0 0.062 13.5 0.0 3.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 EGB11557.1 - 0.00028 20.3 0.1 2.3 7.6 0.0 3.4 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGB11557.1 - 0.00029 21.4 2.3 0.086 13.4 0.0 3.5 4 0 0 4 4 2 1 ABC transporter AAA_30 PF13604.6 EGB11557.1 - 0.0003 20.6 5.7 0.51 10.0 0.0 4.2 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 EGB11557.1 - 0.00043 20.2 0.5 0.53 10.2 0.0 3.8 4 0 0 4 4 2 1 NACHT domain AAA_28 PF13521.6 EGB11557.1 - 0.00043 20.6 0.1 4 7.7 0.0 4.6 5 0 0 5 5 3 0 AAA domain AAA_24 PF13479.6 EGB11557.1 - 0.001 18.9 0.0 0.21 11.3 0.1 3.6 3 0 0 3 3 3 1 AAA domain DUF4164 PF13747.6 EGB11557.1 - 0.0022 18.3 5.0 0.0022 18.3 5.0 4.0 3 0 0 3 3 1 1 Domain of unknown function (DUF4164) RNA_helicase PF00910.22 EGB11557.1 - 0.0034 17.8 0.0 22 5.5 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.6 EGB11557.1 - 0.0053 17.1 1.0 19 5.6 0.0 4.3 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 EGB11557.1 - 0.0056 15.8 0.2 5.6 5.9 0.0 4.0 4 0 0 4 4 4 0 Type II/IV secretion system protein TniB PF05621.11 EGB11557.1 - 0.0063 16.0 0.1 1.4 8.3 0.0 2.9 3 0 0 3 3 3 1 Bacterial TniB protein cobW PF02492.19 EGB11557.1 - 0.0082 15.7 0.0 3.7 7.1 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_2 PF07724.14 EGB11557.1 - 0.019 15.1 0.0 6.9 6.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 EGB11557.1 - 0.028 14.3 0.0 4.7 7.1 0.0 3.2 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 EGB11557.1 - 0.029 14.4 0.0 16 5.6 0.0 3.6 4 0 0 4 4 3 0 AAA domain ATPase PF06745.13 EGB11557.1 - 0.045 13.1 0.0 1.3 8.4 0.0 3.0 3 0 0 3 3 3 0 KaiC AAA_29 PF13555.6 EGB11557.1 - 0.1 12.4 0.1 12 5.8 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EGB11557.1 - 0.11 12.3 0.0 10 5.9 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 EGB11557.1 - 0.14 11.6 2.0 24 4.3 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein Ras PF00071.22 EGB11557.1 - 0.17 11.5 0.1 0.91 9.1 0.0 2.4 2 0 0 2 2 1 0 Ras family AAA_23 PF13476.6 EGB11557.1 - 0.51 10.8 3.4 9.3 6.7 0.0 3.5 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 EGB11557.1 - 1.1 9.0 6.5 14 5.4 0.0 4.1 5 0 0 5 5 3 0 Cytidylate kinase SRP54 PF00448.22 EGB11557.1 - 1.1 8.8 6.2 5.5 6.6 0.0 4.3 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain SesA PF17107.5 EGB11557.1 - 1.8 8.7 8.0 0.86 9.8 1.0 4.3 4 0 0 4 4 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Rhodanese PF00581.20 EGB11558.1 - 4.9e-10 39.9 0.0 1.8e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain TMEM154 PF15102.6 EGB11559.1 - 0.0014 18.6 0.1 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 TMEM154 protein family DUF5527 PF17665.1 EGB11559.1 - 0.099 12.2 1.6 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5527) SIT PF15330.6 EGB11559.1 - 0.12 12.8 0.1 0.22 12.0 0.1 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT ECSCR PF15820.5 EGB11559.1 - 0.14 12.0 0.6 0.78 9.6 0.0 2.4 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator zf_CCCH_4 PF18345.1 EGB11560.1 - 5.1e-17 61.3 30.0 0.00032 20.6 4.4 4.3 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 EGB11560.1 - 3.7e-10 39.4 29.9 0.013 15.4 3.9 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WW PF00397.26 EGB11560.1 - 3.2e-09 36.7 2.6 6.6e-09 35.7 2.6 1.6 1 0 0 1 1 1 1 WW domain Torus PF16131.5 EGB11560.1 - 1.9e-08 35.0 19.6 0.0022 18.7 0.4 4.3 1 1 2 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 EGB11560.1 - 4.2e-06 27.0 7.9 0.00021 21.5 3.3 2.8 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGB11560.1 - 0.0079 16.6 24.1 2.9 8.5 0.4 4.5 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGB11560.1 - 1 9.2 30.5 0.061 13.1 4.1 4.2 4 0 0 4 4 4 0 CCCH-type zinc finger LRV_FeS PF05484.11 EGB11560.1 - 6.4 6.9 14.7 5.1 7.2 0.3 4.3 4 0 0 4 4 4 0 LRV protein FeS4 cluster DEAD PF00270.29 EGB11561.1 - 9.9e-13 48.2 0.2 1.3e-08 34.8 0.0 2.6 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11561.1 - 1.4e-05 25.4 0.0 2.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SET PF00856.28 EGB11561.1 - 0.0033 17.8 0.0 0.25 11.7 0.0 2.7 3 0 0 3 3 3 1 SET domain AAA_22 PF13401.6 EGB11561.1 - 0.004 17.4 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGB11561.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3682 PF12446.8 EGB11561.1 - 0.042 14.3 0.2 0.042 14.3 0.2 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3682) Med19 PF10278.9 EGB11561.1 - 0.38 10.7 6.2 0.75 9.7 6.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ofd1_CTDD PF10637.9 EGB11562.1 - 5.1e-40 137.4 0.0 1.2e-34 119.8 0.0 3.0 3 0 0 3 3 3 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EGB11562.1 - 4.8e-25 88.1 0.0 9.4e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGB11562.1 - 1.4e-13 51.6 0.0 2.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.26 EGB11563.1 - 7.1e-06 25.7 0.0 7.5e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CutC PF03932.14 EGB11564.1 - 2e-28 99.3 6.3 5.3e-27 94.6 6.3 2.0 1 1 0 1 1 1 1 CutC family HEAT PF02985.22 EGB11564.1 - 0.5 10.8 0.0 0.5 10.8 0.0 2.3 3 0 0 3 3 3 0 HEAT repeat Aldo_ket_red PF00248.21 EGB11565.1 - 9.5e-10 38.1 0.0 1.7e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family MTHFR PF02219.17 EGB11566.1 - 7.8e-102 340.5 0.0 9.3e-102 340.2 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MR_MLE_C PF13378.6 EGB11567.1 - 2.1e-48 164.8 0.7 3.6e-48 164.0 0.7 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGB11567.1 - 1.4e-08 35.0 0.0 3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Chol_subst-bind PF09129.11 EGB11567.1 - 0.08 11.9 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding DEAD PF00270.29 EGB11568.1 - 3.1e-46 157.3 0.0 4.4e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11568.1 - 1.1e-27 96.6 0.0 2.8e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB11568.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ocnus PF05005.15 EGB11569.1 - 2.8e-19 69.2 0.0 3.5e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Cas_Csa4 PF09703.10 EGB11569.1 - 0.15 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) GIDA PF01134.22 EGB11570.1 - 1.2e-134 449.3 0.0 1.4e-134 449.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGB11570.1 - 8.2e-61 205.8 0.0 1e-60 205.5 0.0 1.1 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EGB11570.1 - 7.5e-06 25.4 1.4 1.3e-05 24.6 1.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB11570.1 - 2e-05 23.9 4.3 2e-05 23.9 4.3 3.1 3 1 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 EGB11570.1 - 3.6e-05 23.3 8.4 8.1e-05 22.1 8.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB11570.1 - 0.003 18.1 0.9 0.0074 16.8 0.9 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGB11570.1 - 0.005 16.2 0.8 0.01 15.1 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EGB11570.1 - 0.046 13.0 0.1 0.072 12.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PTS-HPr PF00381.19 EGB11570.1 - 0.059 13.6 0.2 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 PTS HPr component phosphorylation site HI0933_like PF03486.14 EGB11570.1 - 0.072 11.8 3.4 0.056 12.1 2.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EGB11570.1 - 0.42 9.6 2.9 0.63 9.0 1.7 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein PH PF00169.29 EGB11571.1 - 3.5e-11 43.5 0.0 8e-06 26.3 0.0 4.1 4 0 0 4 4 4 2 PH domain PDZ_6 PF17820.1 EGB11571.1 - 0.00059 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PH_8 PF15409.6 EGB11571.1 - 0.021 15.1 0.0 0.084 13.2 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Val_tRNA-synt_C PF10458.9 EGB11572.1 - 0.00013 22.2 2.7 0.00037 20.7 2.7 1.9 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm SHMT PF00464.19 EGB11573.1 - 1.5e-194 646.1 0.0 1.8e-194 645.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EGB11573.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DTC PF18102.1 EGB11573.1 - 0.13 12.3 0.2 0.3 11.2 0.0 1.6 2 0 0 2 2 2 0 Deltex C-terminal domain AAA PF00004.29 EGB11574.1 - 4.7e-83 276.2 0.0 1.5e-44 151.6 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB11574.1 - 2.3e-26 91.3 2.3 9.3e-13 47.8 0.1 3.1 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGB11574.1 - 5.6e-14 52.9 1.4 5.8e-06 26.8 0.4 4.0 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 EGB11574.1 - 1.2e-12 47.8 0.0 1.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGB11574.1 - 1.2e-09 38.3 0.0 0.002 18.2 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGB11574.1 - 2.2e-09 37.6 0.0 0.0034 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGB11574.1 - 2.9e-09 36.6 0.0 0.00037 19.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EGB11574.1 - 5.1e-09 36.3 0.0 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EGB11574.1 - 1.3e-08 34.9 0.0 0.0051 16.6 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 EGB11574.1 - 1.5e-08 34.9 0.0 0.0021 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) CDC48_N PF02359.18 EGB11574.1 - 1.7e-07 31.3 0.0 5.9e-07 29.6 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.6 EGB11574.1 - 3.9e-07 30.4 0.4 0.15 12.3 0.0 3.9 3 2 1 4 4 3 2 AAA domain AAA_18 PF13238.6 EGB11574.1 - 4e-07 30.6 0.0 0.026 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGB11574.1 - 4e-07 30.4 0.0 0.0072 16.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 EGB11574.1 - 3.9e-06 27.3 0.0 0.064 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGB11574.1 - 5e-06 26.9 0.0 0.04 14.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 EGB11574.1 - 8e-06 25.6 4.3 0.17 11.4 1.2 3.9 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EGB11574.1 - 1.1e-05 24.9 0.2 0.043 13.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 EGB11574.1 - 1.3e-05 25.1 0.0 0.00024 21.0 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NACHT PF05729.12 EGB11574.1 - 2.9e-05 24.1 0.2 0.25 11.2 0.0 2.9 3 0 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.17 EGB11574.1 - 2.9e-05 23.9 0.2 0.068 12.9 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGB11574.1 - 4.1e-05 23.0 0.0 0.051 12.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 EGB11574.1 - 6.4e-05 23.0 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGB11574.1 - 0.00014 22.4 0.0 0.45 11.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter Rad17 PF03215.15 EGB11574.1 - 0.00021 21.3 0.0 0.19 11.6 0.0 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain Cytidylate_kin2 PF13189.6 EGB11574.1 - 0.00039 20.6 0.1 0.32 11.1 0.1 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family NB-ARC PF00931.22 EGB11574.1 - 0.0004 19.7 0.0 0.83 8.8 0.0 2.6 3 0 0 3 3 3 2 NB-ARC domain Parvo_NS1 PF01057.17 EGB11574.1 - 0.00078 18.6 0.1 0.11 11.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EGB11574.1 - 0.00086 19.0 0.1 2.3 7.9 0.1 3.2 3 1 0 3 3 3 1 Sigma-54 interaction domain DUF815 PF05673.13 EGB11574.1 - 0.00089 18.5 0.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGB11574.1 - 0.0014 18.2 0.0 0.49 9.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 EGB11574.1 - 0.0015 18.4 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EGB11574.1 - 0.0023 17.3 0.0 0.33 10.3 0.0 2.6 2 0 0 2 2 2 1 KaiC SKI PF01202.22 EGB11574.1 - 0.0055 16.9 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase ATPase_2 PF01637.18 EGB11574.1 - 0.008 16.1 0.0 4.5 7.1 0.0 2.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EGB11574.1 - 0.0093 16.1 0.0 3.4 7.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain PduV-EutP PF10662.9 EGB11574.1 - 0.0097 15.7 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 EGB11574.1 - 0.011 15.5 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 EGB11574.1 - 0.015 15.0 0.0 6.3 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EGB11574.1 - 0.017 14.5 0.2 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 EGB11574.1 - 0.023 15.0 0.1 4.1 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGB11574.1 - 0.053 12.8 0.0 8.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 EGB11574.1 - 0.054 14.0 0.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGB11574.1 - 0.072 12.9 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 EGB11574.1 - 0.15 11.4 0.1 17 4.7 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_29 PF13555.6 EGB11574.1 - 0.19 11.5 0.0 23 4.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Hydin_ADK PF17213.3 EGB11574.1 - 0.21 11.8 3.7 3 8.1 0.1 3.2 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain Bac_DnaA PF00308.18 EGB11574.1 - 0.22 11.3 0.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein zf-C3HC4_3 PF13920.6 EGB11575.1 - 4.9e-11 42.3 7.1 4.9e-11 42.3 7.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGB11575.1 - 2.7e-05 23.9 7.3 2.7e-05 23.9 7.3 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 CDC45 PF02724.14 EGB11575.1 - 0.051 11.9 0.1 0.08 11.2 0.1 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-RING_5 PF14634.6 EGB11575.1 - 0.59 10.1 7.0 1.6 8.8 7.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Peptidase_M41 PF01434.18 EGB11576.1 - 5.2e-56 189.5 0.0 1.1e-55 188.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGB11576.1 - 6.5e-43 146.3 0.0 1.8e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB11576.1 - 9.9e-12 44.5 1.1 6.6e-11 41.8 0.2 2.7 3 0 0 3 3 3 1 AAA+ lid domain AAA_16 PF13191.6 EGB11576.1 - 3.7e-05 24.2 0.2 0.0018 18.7 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGB11576.1 - 9.7e-05 22.2 0.0 0.00041 20.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGB11576.1 - 0.00044 19.6 0.1 0.0008 18.7 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain FtsH_ext PF06480.15 EGB11576.1 - 0.0011 19.3 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 EGB11576.1 - 0.006 16.6 0.4 0.044 13.8 0.4 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGB11576.1 - 0.0065 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EGB11576.1 - 0.0081 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB11576.1 - 0.019 15.2 0.1 0.41 10.9 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EGB11576.1 - 0.022 14.9 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGB11576.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGB11576.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGB11576.1 - 0.091 12.5 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EGB11576.1 - 0.11 12.0 0.0 0.52 9.8 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EGB11576.1 - 0.12 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGB11576.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peptidase_M50B PF13398.6 EGB11576.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase M50B-like EF-hand_7 PF13499.6 EGB11579.1 - 1.1e-14 54.6 1.2 1.3e-14 54.3 1.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB11579.1 - 7.9e-12 43.8 4.8 6.1e-06 25.4 0.4 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGB11579.1 - 6.8e-10 38.0 5.7 5.3e-06 25.7 0.9 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB11579.1 - 7.5e-10 38.5 4.6 0.00011 22.0 0.8 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB11579.1 - 2.8e-09 36.2 5.1 2e-06 27.3 0.9 2.3 1 1 1 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 EGB11579.1 - 5.5e-06 26.6 0.1 6.6e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGB11579.1 - 0.021 15.1 0.1 0.024 15.0 0.1 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3349 PF11829.8 EGB11579.1 - 0.034 14.9 0.0 0.041 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Myotub-related PF06602.14 EGB11580.1 - 5.1e-77 259.2 0.0 5.9e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGB11580.1 - 7.8e-05 22.7 0.3 0.00011 22.3 0.3 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGB11580.1 - 0.0015 18.4 0.2 0.0022 17.8 0.2 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB11580.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase His_Phos_1 PF00300.22 EGB11581.1 - 2.5e-32 112.2 0.0 4.1e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 EGB11581.1 - 1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_12 PF13087.6 EGB11582.1 - 3.7e-13 49.6 0.0 9.4e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB11582.1 - 9.9e-12 45.0 1.3 1.7e-05 24.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EGB11582.1 - 1.8e-11 44.3 0.0 8.4e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain ShK PF01549.24 EGB11582.1 - 2.4e-07 31.2 6.5 5.4e-07 30.0 6.5 1.6 1 0 0 1 1 1 1 ShK domain-like AAA_19 PF13245.6 EGB11582.1 - 6.3e-06 26.6 0.4 0.004 17.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain MTES_1575 PF18741.1 EGB11582.1 - 1.3e-05 25.3 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 REase_MTES_1575 Viral_helicase1 PF01443.18 EGB11582.1 - 1.3e-05 25.1 0.2 0.35 10.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase CBFD_NFYB_HMF PF00808.23 EGB11582.1 - 0.0033 17.7 0.0 0.0085 16.4 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Helicase_RecD PF05127.14 EGB11582.1 - 0.0042 17.0 0.1 0.32 10.8 0.0 2.5 2 0 0 2 2 2 1 Helicase 2OG-FeII_Oxy_3 PF13640.6 EGB11582.1 - 0.057 14.3 0.0 0.34 11.8 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily AAA_22 PF13401.6 EGB11582.1 - 0.069 13.4 0.2 0.3 11.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain CDC27 PF09507.10 EGB11582.1 - 0.16 11.3 5.0 0.26 10.6 5.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Histone PF00125.24 EGB11582.1 - 1.6 9.1 5.7 0.53 10.6 0.0 2.3 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 IBN_N PF03810.19 EGB11583.1 - 0.0052 16.7 0.0 0.024 14.6 0.0 2.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HATPase_c_2 PF13581.6 EGB11583.1 - 0.41 10.6 5.1 0.36 10.8 1.5 2.5 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Na_Ca_ex PF01699.24 EGB11584.1 - 5.9e-07 29.6 8.6 6.5e-07 29.4 8.6 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Methyltransf_24 PF13578.6 EGB11585.1 - 1.7e-15 58.0 0.1 2e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB11585.1 - 0.018 15.7 0.0 0.18 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGB11585.1 - 0.043 14.5 0.0 0.076 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB11585.1 - 0.072 13.8 0.0 0.37 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain ArfGap PF01412.18 EGB11587.1 - 1.8e-24 86.1 0.1 1.8e-24 86.1 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF1918 PF08940.11 EGB11587.1 - 0.00032 20.2 0.4 0.0076 15.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1918) zf-B_box PF00643.24 EGB11587.1 - 0.17 12.1 0.5 0.26 11.5 0.5 1.2 1 0 0 1 1 1 0 B-box zinc finger CNDH2_C PF16858.5 EGB11587.1 - 0.37 10.6 6.3 0.55 10.1 6.3 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DAHP_synth_2 PF01474.16 EGB11588.1 - 5.5e-184 611.7 0.0 6.2e-184 611.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family dCache_1 PF02743.18 EGB11589.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Cache domain 2OG-FeII_Oxy_3 PF13640.6 EGB11590.1 - 4.5e-06 27.5 0.0 6.3e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.19 EGB11591.1 - 2.3e-15 56.1 0.1 2.3e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 Actin CCDC53 PF10152.9 EGB11593.1 - 3.7e-32 111.9 0.3 2.9e-18 66.7 0.1 2.1 1 1 1 2 2 2 2 Subunit CCDC53 of WASH complex Amino_oxidase PF01593.24 EGB11594.1 - 7.1e-19 68.4 1.4 4.5e-18 65.8 1.4 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB11594.1 - 2.3e-15 56.6 2.1 3.6e-15 56.0 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGB11594.1 - 4.1e-11 42.6 5.5 7.2e-06 25.3 1.3 3.3 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EGB11594.1 - 6e-11 42.5 6.4 1.4e-07 31.4 0.4 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB11594.1 - 3.9e-06 27.3 0.0 0.0001 22.8 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB11594.1 - 1e-05 24.9 1.2 3e-05 23.4 0.2 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGB11594.1 - 2e-05 24.2 0.5 4.2e-05 23.1 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGB11594.1 - 2.2e-05 23.9 0.3 3.6e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGB11594.1 - 8.6e-05 21.9 0.9 0.00015 21.1 0.9 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGB11594.1 - 0.0025 17.0 0.6 0.0068 15.5 1.1 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGB11594.1 - 0.005 15.6 0.2 0.019 13.7 0.3 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EGB11594.1 - 0.053 12.8 1.5 0.095 12.0 1.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGB11594.1 - 0.11 12.4 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EGB11594.1 - 0.2 10.5 0.5 0.29 10.0 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 EGB11594.1 - 0.21 10.3 0.1 0.3 9.8 0.1 1.1 1 0 0 1 1 1 0 MCRA family Lycopene_cycl PF05834.12 EGB11594.1 - 1.3 8.0 4.3 0.26 10.3 0.4 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Tub PF01167.18 EGB11595.1 - 1.5e-88 296.6 0.0 1.7e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 EGB11595.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) adh_short PF00106.25 EGB11596.1 - 3.7e-32 111.4 0.0 5.6e-25 87.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGB11596.1 - 6.7e-27 94.5 0.2 1e-18 67.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB11596.1 - 5.8e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DnaJ PF00226.31 EGB11597.1 - 1.2e-11 44.6 0.0 2.9e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EGB11597.1 - 1.2e-11 43.9 19.1 4.1e-08 32.7 0.0 6.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11597.1 - 4.8e-07 29.4 39.3 7.6e-05 22.5 0.1 8.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB11597.1 - 4.4e-06 26.3 5.6 0.14 11.8 0.0 4.9 5 0 0 5 5 5 3 TPR repeat TPR_12 PF13424.6 EGB11597.1 - 0.00068 19.9 2.2 0.00068 19.9 2.2 8.2 9 1 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11597.1 - 0.0011 19.5 10.7 0.0011 19.5 10.7 9.0 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11597.1 - 0.0035 17.4 5.2 0.3 11.4 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB11597.1 - 0.32 11.5 2.3 29 5.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11597.1 - 2.1 8.9 28.9 0.69 10.5 0.2 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Nop PF01798.18 EGB11598.1 - 2.5e-84 282.4 0.4 2.5e-84 282.4 0.4 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGB11598.1 - 2.6e-13 50.1 1.9 2.6e-13 50.1 1.9 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Cpn60_TCP1 PF00118.24 EGB11598.1 - 8.3e-05 21.4 0.4 0.00014 20.7 0.4 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4604 PF15377.6 EGB11598.1 - 0.06 13.8 19.7 0.13 12.7 19.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RNA_polI_A34 PF08208.11 EGB11598.1 - 0.32 11.0 21.1 0.53 10.3 21.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 rhaM PF05336.13 EGB11599.1 - 5.9e-17 61.7 0.0 6.3e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase AMP-binding PF00501.28 EGB11600.1 - 2.2e-42 145.1 0.0 2.5e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Anoctamin PF04547.12 EGB11601.1 - 1.8e-104 350.1 15.0 2.4e-104 349.7 15.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 EGB11601.1 - 0.01 15.6 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DEAD PF00270.29 EGB11602.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGB11602.1 - 0.00024 20.9 1.7 0.00081 19.2 1.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB11602.1 - 0.00041 20.7 0.0 0.00063 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGB11602.1 - 0.00046 19.6 0.0 0.00096 18.6 0.0 1.4 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 EGB11602.1 - 0.0015 17.7 0.2 0.067 12.2 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EGB11602.1 - 0.0055 15.7 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Rad17 PF03215.15 EGB11602.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 EGB11602.1 - 0.064 13.5 0.6 0.15 12.3 0.6 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGB11602.1 - 0.081 12.2 2.1 0.58 9.4 0.2 2.2 1 1 1 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 EGB11602.1 - 0.14 11.9 0.2 1.1 9.0 0.2 2.3 1 1 0 1 1 1 0 Thymidylate kinase H_PPase PF03030.16 EGB11603.1 - 3.1e-240 799.3 31.6 3.7e-240 799.0 31.6 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DEAD PF00270.29 EGB11604.1 - 1.6e-39 135.5 0.0 2.4e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11604.1 - 2.8e-18 66.3 0.0 1.6e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB11604.1 - 9.5e-09 35.5 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 EGB11604.1 - 0.00012 22.3 0.2 0.00056 20.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 EGB11604.1 - 0.021 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGB11604.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain RibD_C PF01872.17 EGB11605.1 - 5.4e-27 94.9 0.0 6.1e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Sel1 PF08238.12 EGB11607.1 - 1.7e-45 152.4 32.3 6.2e-10 39.4 0.1 8.4 8 1 0 8 8 8 7 Sel1 repeat TPR_16 PF13432.6 EGB11607.1 - 9.1e-06 26.2 27.7 0.078 13.6 3.0 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11607.1 - 0.00069 19.9 16.6 0.023 15.0 0.3 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat EF-hand_like PF09279.11 EGB11607.1 - 0.0016 18.9 0.8 0.13 12.7 0.1 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like PhoD PF09423.10 EGB11607.1 - 0.0074 15.3 1.7 1.6 7.6 0.2 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase TPR_10 PF13374.6 EGB11607.1 - 0.015 15.1 19.6 0.072 13.0 0.3 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat AAA_lid_10 PF17872.1 EGB11607.1 - 0.021 14.9 0.4 4.5 7.5 0.2 2.5 2 1 0 2 2 2 0 AAA lid domain DUF410 PF04190.13 EGB11607.1 - 0.028 14.2 0.6 0.91 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_1 PF00515.28 EGB11607.1 - 0.03 14.2 0.6 0.03 14.2 0.6 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGB11607.1 - 0.61 10.1 5.9 1.9 8.6 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11607.1 - 9.6 6.7 19.2 2.1 8.8 0.3 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat Nucleotid_trans PF03407.16 EGB11608.1 - 0.002 18.2 0.0 0.0043 17.0 0.0 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glycos_transf_2 PF00535.26 EGB11608.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Dak1 PF02733.17 EGB11608.1 - 0.1 11.5 0.4 0.17 10.7 0.4 1.2 1 0 0 1 1 1 0 Dak1 domain GAF PF01590.26 EGB11609.1 - 1.6e-05 25.6 0.1 4.3e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 GAF domain Rtf2 PF04641.12 EGB11610.1 - 6.1e-12 45.5 0.0 2.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Rtf2 RING-finger zf-NOSIP PF15906.5 EGB11610.1 - 1.5e-08 34.6 0.0 1.1e-07 31.9 0.0 2.3 2 1 1 3 3 3 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 EGB11610.1 - 0.00032 20.8 0.0 0.0017 18.5 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 EGB11610.1 - 0.0028 17.4 0.0 0.051 13.4 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SLT_L PF14718.6 EGB11610.1 - 0.059 13.5 2.4 0.1 12.8 2.4 1.3 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain TP6A_N PF04406.14 EGB11611.1 - 3.1e-21 75.1 0.0 7.8e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF1899 PF08953.11 EGB11612.1 - 1.2e-19 69.9 0.0 2.1e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGB11612.1 - 3.2e-18 65.4 0.1 5.9e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGB11612.1 - 1e-16 61.0 0.3 0.0038 18.0 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11612.1 - 0.00029 21.1 0.0 0.13 12.6 0.1 3.7 1 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PI3_PI4_kinase PF00454.27 EGB11613.1 - 3.3e-66 223.7 0.0 7e-66 222.6 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EGB11613.1 - 9.8e-59 199.3 0.0 1.6e-58 198.6 0.0 1.3 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 EGB11613.1 - 2.1e-39 135.0 0.0 6.4e-39 133.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGB11613.1 - 3.5e-36 123.6 0.0 1.1e-35 122.0 0.0 2.0 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 EGB11613.1 - 1.7e-15 56.5 0.5 4.5e-15 55.2 0.5 1.8 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 EGB11613.1 - 2.8e-06 27.7 13.2 0.0021 18.5 0.0 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB11613.1 - 0.025 14.8 0.6 0.82 9.9 0.0 3.5 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGB11613.1 - 0.071 13.2 2.7 2.8 8.2 0.2 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT PF02985.22 EGB11613.1 - 0.13 12.6 0.1 0.13 12.6 0.1 10.4 12 0 0 12 12 10 0 HEAT repeat Adaptin_N PF01602.20 EGB11613.1 - 0.21 10.1 0.4 10 4.5 0.1 2.4 2 0 0 2 2 2 0 Adaptin N terminal region CAP_N PF01213.19 EGB11613.1 - 0.67 9.4 1.7 1.4 8.4 1.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Yip1 PF04893.17 EGB11614.1 - 7.2e-05 22.6 12.8 0.00012 21.9 12.8 1.4 1 1 0 1 1 1 1 Yip1 domain HrpB1_HrpK PF09613.10 EGB11614.1 - 0.095 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) RseC_MucC PF04246.12 EGB11614.1 - 3.6 7.5 9.3 0.33 10.9 2.1 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC eIF-5_eIF-2B PF01873.17 EGB11615.1 - 1.9e-39 134.2 0.1 2.3e-39 133.9 0.1 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 EGB11615.1 - 0.056 13.8 0.3 0.29 11.5 0.3 2.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar DnaJ PF00226.31 EGB11616.1 - 3.8e-19 68.6 0.1 4.2e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 DnaJ domain VCBS PF13517.6 EGB11617.1 - 7.4e-102 334.0 202.6 5.7e-10 39.6 8.1 20.9 3 3 18 21 21 21 21 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DTW PF03942.15 EGB11617.1 - 1.1e-29 103.6 0.0 6.1e-29 101.2 0.0 2.3 3 0 0 3 3 3 1 DTW domain REJ PF02010.15 EGB11617.1 - 7.4e-17 61.3 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 REJ domain AbfS_sensor PF18225.1 EGB11617.1 - 8.1e-12 44.9 0.0 35 4.4 0.0 12.2 16 0 0 16 16 16 0 Sensor histidine kinase (AbfS) sensor domain ECH_2 PF16113.5 EGB11617.1 - 4.8e-08 32.9 2.1 1.7e-07 31.1 1.1 2.2 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase SASA PF03629.18 EGB11617.1 - 5.5e-07 29.4 0.1 4.3e-06 26.6 0.0 2.3 2 1 0 2 2 2 1 Carbohydrate esterase, sialic acid-specific acetylesterase CH PF00307.31 EGB11618.1 - 1.1e-27 96.3 0.0 3.7e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGB11618.1 - 0.018 14.8 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 0 CAMSAP CH domain WD40 PF00400.32 EGB11620.1 - 1e-09 38.8 4.1 0.013 16.4 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.6 EGB11620.1 - 7.4 7.2 7.0 6.8 7.3 0.1 3.4 3 2 0 3 3 3 0 PQQ-like domain Choline_transpo PF04515.12 EGB11621.1 - 1.6e-25 90.0 22.8 1.6e-25 90.0 22.8 1.7 2 0 0 2 2 2 1 Plasma-membrane choline transporter Gly-zipper_Omp PF13488.6 EGB11621.1 - 2.6 8.1 7.8 6.6 6.8 7.8 1.7 1 0 0 1 1 1 0 Glycine zipper Methyltransf_21 PF05050.12 EGB11622.1 - 2.4e-12 47.2 0.0 3.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 EGB11622.1 - 0.058 13.2 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.6 EGB11623.1 - 1.5e-05 25.4 0.1 4.1e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB11623.1 - 5.7e-05 22.7 0.4 0.55 10.3 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGB11623.1 - 0.00016 21.0 1.2 1.1 9.0 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGB11623.1 - 0.00067 19.4 1.0 0.12 12.3 0.1 3.0 4 0 0 4 4 4 2 EF-hand domain pair PRTP PF01366.18 EGB11623.1 - 0.63 8.0 2.6 0.77 7.7 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Ank_2 PF12796.7 EGB11624.1 - 3.6e-08 33.9 0.0 5.3e-07 30.1 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGB11624.1 - 4.2e-08 33.3 1.2 0.1 13.1 0.0 5.0 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGB11624.1 - 1.2e-06 28.3 0.3 0.73 10.6 0.0 4.6 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGB11624.1 - 1.9e-06 28.0 2.9 0.0013 19.0 0.1 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB11624.1 - 2.7e-06 27.8 0.0 0.032 14.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Fez1 PF06818.15 EGB11624.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Fez1 TMF_TATA_bd PF12325.8 EGB11624.1 - 0.071 13.3 1.2 0.13 12.5 0.2 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Methyltransf_16 PF10294.9 EGB11626.1 - 7.2e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EGB11626.1 - 0.00043 19.8 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB11626.1 - 0.00067 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB11626.1 - 0.0024 18.5 0.0 0.0078 16.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB11626.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB11626.1 - 0.15 12.8 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cupin_3 PF05899.12 EGB11626.1 - 0.16 11.7 0.1 0.58 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) PsbQ PF05757.11 EGB11626.1 - 0.36 10.5 3.0 0.4 10.4 0.2 2.4 3 0 0 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) SET PF00856.28 EGB11627.1 - 3.8e-11 43.7 0.0 9.2e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 SET domain Pro_isomerase PF00160.21 EGB11628.1 - 5e-42 143.8 0.0 5.5e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArabFuran-catal PF09206.11 EGB11629.1 - 2.1e-107 359.1 6.0 2.5e-107 358.9 6.0 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic ABC_membrane PF00664.23 EGB11630.1 - 1e-73 248.4 0.1 1.1e-39 136.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGB11630.1 - 1.5e-61 206.9 0.0 1.5e-32 113.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGB11630.1 - 2.7e-14 53.2 0.1 0.00012 21.6 0.0 4.4 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGB11630.1 - 3.6e-11 43.7 6.9 3e-05 24.5 0.5 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGB11630.1 - 2.9e-08 33.3 0.2 0.0069 16.1 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB11630.1 - 1.1e-07 32.1 0.5 0.039 14.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGB11630.1 - 1.3e-06 28.5 0.1 0.14 12.1 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_30 PF13604.6 EGB11630.1 - 9.5e-06 25.5 3.6 0.0048 16.6 0.1 3.4 3 2 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EGB11630.1 - 1.8e-05 24.3 0.0 0.041 13.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EGB11630.1 - 0.00011 22.4 0.2 0.52 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EGB11630.1 - 0.00018 20.4 0.8 0.078 11.8 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 EGB11630.1 - 0.00024 21.1 0.0 1 9.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EGB11630.1 - 0.00028 20.7 0.0 0.66 9.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 EGB11630.1 - 0.00032 20.0 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 EGB11630.1 - 0.0004 20.0 0.1 1.3 8.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_21 PF13304.6 EGB11630.1 - 0.00053 19.9 1.8 0.77 9.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EGB11630.1 - 0.001 18.4 1.9 0.13 11.6 0.1 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_23 PF13476.6 EGB11630.1 - 0.0032 18.0 0.1 1 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGB11630.1 - 0.0044 17.1 0.0 2.5 8.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EGB11630.1 - 0.006 17.0 0.2 9.3 6.7 0.1 4.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 EGB11630.1 - 0.0065 16.3 0.3 1.7 8.3 0.1 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF3987 PF13148.6 EGB11630.1 - 0.0068 15.5 5.1 0.11 11.5 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) SbcCD_C PF13558.6 EGB11630.1 - 0.0084 16.3 8.2 1.2 9.4 0.5 4.3 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 EGB11630.1 - 0.014 15.5 0.6 0.69 10.0 0.0 2.8 4 0 0 4 4 2 0 Helicase HerA, central domain AAA_18 PF13238.6 EGB11630.1 - 0.02 15.4 0.1 7.4 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGB11630.1 - 0.025 14.9 0.4 12 6.4 0.0 2.8 3 0 0 3 3 2 0 RNA helicase APS_kinase PF01583.20 EGB11630.1 - 0.033 14.1 0.4 8.6 6.2 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_10 PF12846.7 EGB11630.1 - 0.037 13.0 0.0 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.17 EGB11630.1 - 0.038 13.7 0.4 12 5.6 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein PRK PF00485.18 EGB11630.1 - 0.038 13.7 0.4 11 5.6 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MoaE PF02391.17 EGB11630.1 - 0.041 14.1 0.2 13 6.1 0.0 2.8 2 0 0 2 2 2 0 MoaE protein AAA_24 PF13479.6 EGB11630.1 - 0.051 13.3 0.0 5.1 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dala_Dala_lig_N PF01820.21 EGB11630.1 - 0.076 13.5 0.2 8.3 6.9 0.0 3.0 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Roc PF08477.13 EGB11630.1 - 0.084 13.1 0.1 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EGB11630.1 - 0.086 12.8 0.1 14 5.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 EGB11630.1 - 0.13 12.0 0.0 5 6.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 EGB11630.1 - 0.21 11.0 0.0 33 3.8 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein NTPase_1 PF03266.15 EGB11630.1 - 0.23 11.4 0.1 48 3.8 0.0 3.1 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 EGB11630.1 - 0.23 10.6 0.0 18 4.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DEAD PF00270.29 EGB11630.1 - 0.24 11.2 0.7 30 4.3 0.2 3.6 3 1 0 3 3 3 0 DEAD/DEAH box helicase ABC1 PF03109.16 EGB11631.1 - 4.9e-19 68.7 0.1 9.4e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 ABC1 family EF-hand_1 PF00036.32 EGB11632.1 - 0.004 16.6 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 EF hand Mus7 PF09462.10 EGB11632.1 - 0.023 13.6 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family EF-hand_6 PF13405.6 EGB11632.1 - 0.046 13.7 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EGB11632.1 - 0.049 14.1 0.1 0.19 12.2 0.1 1.9 1 1 0 1 1 1 0 EF-hand domain pair DUF1631 PF07793.11 EGB11632.1 - 0.072 11.5 0.1 0.098 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RAG2 PF03089.14 EGB11632.1 - 0.24 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Recombination activating protein 2 MIOX PF05153.15 EGB11633.1 - 1.2e-90 303.5 0.0 1.4e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase AstE_AspA PF04952.14 EGB11634.1 - 3.4e-36 124.8 0.0 4.8e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Tyrosinase PF00264.20 EGB11635.1 - 5.4e-07 30.1 1.0 5.4e-07 30.1 1.0 2.7 2 1 0 2 2 2 1 Common central domain of tyrosinase NAD_binding_1 PF00175.21 EGB11635.1 - 2.5e-06 28.1 0.0 1.2e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PDZ_3 PF17815.1 EGB11636.1 - 3.4e-36 124.3 0.0 5e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 EGB11636.1 - 2.7e-13 51.1 0.5 7e-13 49.7 0.5 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EGB11636.1 - 3.1e-06 27.4 0.1 2e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 EGB11636.1 - 2e-05 24.6 0.1 4.7e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Trypsin PDZ PF00595.24 EGB11636.1 - 0.00068 19.9 0.0 0.0019 18.5 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGB11636.1 - 0.0007 19.4 0.8 0.2 11.5 0.1 3.0 3 0 0 3 3 3 1 PDZ domain Peptidase_S46 PF10459.9 EGB11636.1 - 0.0018 17.0 0.1 0.0026 16.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase S46 Tricorn_PDZ PF14685.6 EGB11636.1 - 0.023 14.7 0.2 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Tricorn protease PDZ domain Pr_beta_C PF12465.8 EGB11636.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Proteasome beta subunits C terminal Sel1 PF08238.12 EGB11638.1 - 6.7e-39 131.5 25.4 5.1e-08 33.3 0.1 8.7 8 0 0 8 8 8 7 Sel1 repeat zf-MYND PF01753.18 EGB11638.1 - 2.4e-06 27.5 9.5 2.4e-06 27.5 9.5 2.8 2 1 0 2 2 2 1 MYND finger zf-C3HC4_3 PF13920.6 EGB11638.1 - 6.2e-05 22.8 26.9 0.0032 17.3 12.6 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB11638.1 - 0.0078 16.5 14.7 0.0078 16.5 14.7 2.8 2 0 0 2 2 2 1 Ring finger domain Cobalamin_bind PF01122.19 EGB11638.1 - 0.012 14.6 0.0 1 8.2 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic cobalamin-binding protein DUF5312 PF17239.2 EGB11638.1 - 0.067 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5312) TetR_C_11 PF16859.5 EGB11638.1 - 1.8 8.9 0.0 1.8 8.9 0.0 5.9 5 2 1 6 6 6 0 Tetracyclin repressor-like, C-terminal domain Ecl1 PF12855.7 EGB11638.1 - 2.4 9.3 7.9 0.41 11.8 2.5 2.0 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins MIT PF04212.18 EGB11638.1 - 5.2 7.2 9.8 1.1 9.3 0.1 4.6 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF3395 PF11875.8 EGB11639.1 - 2.3e-10 40.6 0.0 0.051 13.5 0.0 4.6 5 0 0 5 5 5 3 Domain of unknown function (DUF3395) Arm PF00514.23 EGB11639.1 - 4.2e-09 36.1 6.8 1.8e-06 27.8 0.1 4.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Gal_Lectin PF02140.18 EGB11639.1 - 2.7e-05 24.5 0.0 0.83 10.1 0.0 4.7 6 1 0 6 6 6 1 Galactose binding lectin domain zinc_ribbon_4 PF13717.6 EGB11639.1 - 0.29 11.1 3.0 0.81 9.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HEAT PF02985.22 EGB11639.1 - 0.3 11.4 8.1 11 6.6 0.4 5.0 5 0 0 5 5 5 0 HEAT repeat zf-ACC PF17848.1 EGB11639.1 - 0.47 10.6 1.9 1.2 9.3 1.9 1.7 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Zn_Tnp_IS1595 PF12760.7 EGB11639.1 - 6.3 6.9 6.6 2.5 8.2 1.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PSP PF04046.16 EGB11640.1 - 4.6e-22 77.6 6.0 8.3e-22 76.8 6.0 1.4 1 0 0 1 1 1 1 PSP DUF382 PF04037.13 EGB11640.1 - 3.6e-11 43.3 0.0 5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF382) TPR_2 PF07719.17 EGB11641.1 - 0.0041 17.1 38.1 0.52 10.5 1.7 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat Sulfotransfer_3 PF13469.6 EGB11641.1 - 0.0046 17.4 0.3 0.26 11.6 0.0 2.6 2 0 0 2 2 2 1 Sulfotransferase family TPR_11 PF13414.6 EGB11641.1 - 0.0048 16.6 0.7 0.0048 16.6 0.7 4.6 5 0 0 5 5 5 2 TPR repeat TPR_17 PF13431.6 EGB11641.1 - 0.017 15.4 0.5 2.1 8.9 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Nucleotid_trans PF03407.16 EGB11641.1 - 0.025 14.6 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase Ank_4 PF13637.6 EGB11642.1 - 8.2e-17 61.4 3.4 3.5e-15 56.1 0.8 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB11642.1 - 1.2e-15 57.1 5.2 4.8e-07 29.9 0.7 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGB11642.1 - 4.2e-15 55.6 2.1 8.2e-09 35.6 0.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11642.1 - 1.6e-13 51.0 0.7 4.2e-13 49.7 0.7 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB11642.1 - 1.4e-12 46.5 1.3 2.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Hexapep PF00132.24 EGB11644.1 - 1.2e-09 37.5 5.5 1.2e-05 24.8 1.6 2.9 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB11644.1 - 4.5e-06 26.3 10.0 0.00017 21.2 3.6 3.1 2 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 EGB11644.1 - 0.0063 16.9 0.3 0.0096 16.3 0.3 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal FANCL_C PF11793.8 EGB11645.1 - 1.6e-05 25.0 4.6 2.9e-05 24.1 4.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EGB11645.1 - 5.3e-05 23.5 13.3 5.3e-05 23.5 13.3 1.6 2 0 0 2 2 1 1 Ring finger domain C1_1 PF00130.22 EGB11645.1 - 0.0042 17.0 4.0 0.0042 17.0 4.0 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 EGB11645.1 - 0.0044 17.1 9.8 0.0055 16.8 8.9 1.7 2 0 0 2 2 2 1 RING-variant domain RNA_POL_M_15KD PF02150.16 EGB11645.1 - 0.08 12.8 1.7 0.15 12.0 1.7 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit PHD PF00628.29 EGB11645.1 - 0.13 12.1 10.7 0.23 11.4 10.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 EGB11645.1 - 0.81 9.8 9.0 1.6 8.9 9.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGB11645.1 - 1 9.1 14.4 0.3 10.7 9.3 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EGB11645.1 - 2.8 8.1 11.0 26 5.0 10.0 2.7 2 1 0 2 2 2 0 KIAA1045 RING finger zf-C3HC4 PF00097.25 EGB11645.1 - 2.9 7.8 12.4 5.5 7.0 12.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGB11645.1 - 5.4 7.4 15.5 1.2 9.5 11.8 1.8 2 0 0 2 2 2 0 RING-like domain PHD_4 PF16866.5 EGB11645.1 - 6.2 7.0 11.6 35 4.6 0.1 2.8 1 1 1 2 2 2 0 PHD-finger zf-C3HC4_2 PF13923.6 EGB11645.1 - 7.8 6.4 12.9 49 3.9 12.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ThiF PF00899.21 EGB11646.1 - 1.5e-70 237.4 0.8 1.7e-70 237.2 0.8 1.0 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EGB11646.1 - 5.8e-09 36.2 0.0 5.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EGB11646.1 - 0.00058 20.3 0.3 0.0022 18.4 0.1 2.1 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGB11646.1 - 0.034 14.2 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGB11646.1 - 0.13 12.9 0.2 0.25 11.9 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_1_4 PF13692.6 EGB11648.1 - 4.6e-15 56.2 0.0 1.3e-14 54.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 ACT PF01842.25 EGB11648.1 - 9.9e-14 50.8 0.2 5.9e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 ACT domain Glycos_transf_1 PF00534.20 EGB11648.1 - 2.5e-13 49.9 0.0 4.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 BiPBP_C PF06832.12 EGB11648.1 - 2.9e-05 24.0 0.1 0.00027 20.9 0.0 2.7 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Glyco_transf_4 PF13439.6 EGB11648.1 - 8.2e-05 22.7 0.0 0.00035 20.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EGB11648.1 - 0.00031 21.1 0.0 0.0011 19.3 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 ACT_4 PF13291.6 EGB11648.1 - 0.00043 20.8 0.0 0.32 11.6 0.0 2.3 2 0 0 2 2 2 2 ACT domain AOX PF01786.17 EGB11649.1 - 1.9e-07 30.9 0.4 2e-07 30.8 0.4 1.0 1 0 0 1 1 1 1 Alternative oxidase COPIIcoated_ERV PF07970.12 EGB11650.1 - 3.7e-16 59.6 0.2 1.6e-15 57.6 0.2 1.8 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGB11650.1 - 6.1e-10 39.3 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF5069 PF16798.5 EGB11650.1 - 0.047 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) TGT PF01702.18 EGB11651.1 - 4.8e-102 341.7 0.0 7.9e-72 242.3 0.0 2.0 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase Aldo_ket_red PF00248.21 EGB11652.1 - 1.2e-46 159.3 0.0 2.3e-45 155.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Hexapep PF00132.24 EGB11653.1 - 8.6e-09 34.8 0.1 0.036 13.8 0.0 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB11653.1 - 0.011 15.4 0.0 5.5 6.8 0.0 3.4 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Baculo_helicase PF04735.12 EGB11654.1 - 0.16 9.4 0.1 0.23 9.0 0.1 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase MutS_V PF00488.21 EGB11655.1 - 1.3e-58 198.2 0.0 1.4e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 MutS domain V Dus PF01207.17 EGB11656.1 - 4.1e-15 55.7 0.0 5e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Cnn_1N PF07989.11 EGB11657.1 - 1.8 8.8 4.8 2.2 8.5 0.1 2.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Tropomyosin_1 PF12718.7 EGB11657.1 - 8.8 6.5 20.0 8.5 6.5 3.5 3.2 2 1 1 3 3 3 0 Tropomyosin like DUF2203 PF09969.9 EGB11657.1 - 9.7 6.9 9.6 1.5e+02 3.1 7.6 3.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sel1 PF08238.12 EGB11658.1 - 1.4e-29 101.9 13.3 1.3e-08 35.2 0.0 6.2 6 1 0 6 6 6 5 Sel1 repeat TPR_1 PF00515.28 EGB11658.1 - 0.0031 17.2 4.7 5.9 6.9 0.1 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat PPR PF01535.20 EGB11658.1 - 0.012 15.8 2.6 4.7 7.7 0.0 4.0 5 0 0 5 5 5 0 PPR repeat TPR_6 PF13174.6 EGB11658.1 - 0.012 16.1 5.5 7.7 7.4 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11658.1 - 0.024 14.8 10.5 5.2 7.4 0.1 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat AAA_lid_10 PF17872.1 EGB11658.1 - 0.024 14.7 0.4 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA lid domain TPR_16 PF13432.6 EGB11658.1 - 0.026 15.2 8.8 3.5 8.4 1.4 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11658.1 - 0.043 14.1 4.1 3.8 7.9 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11658.1 - 0.056 13.3 3.2 10 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_1 PF12854.7 EGB11658.1 - 0.057 13.1 0.1 0.22 11.2 0.1 2.0 1 0 0 1 1 1 0 PPR repeat DUF977 PF06163.11 EGB11658.1 - 0.058 13.4 0.3 0.72 9.8 0.1 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF977) Epimerase PF01370.21 EGB11659.1 - 0.00027 20.5 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YL1 PF05764.13 EGB11660.1 - 0.00056 20.1 10.7 0.00056 20.1 10.7 3.2 4 1 0 4 4 4 1 YL1 nuclear protein CDC45 PF02724.14 EGB11660.1 - 0.014 13.7 6.6 0.032 12.6 6.6 1.5 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGB11660.1 - 0.66 8.1 9.9 1.2 7.2 9.9 1.4 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 EGB11660.1 - 4.1 7.2 8.0 11 5.8 8.0 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein RRN3 PF05327.11 EGB11660.1 - 8.6 4.8 5.0 15 3.9 5.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sulfatase PF00884.23 EGB11661.1 - 1.3e-33 116.7 0.0 2.2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 EGB11661.1 - 9.6e-05 23.1 0.1 0.00034 21.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 EGB11661.1 - 0.15 11.7 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase VCBS PF13517.6 EGB11662.1 - 1.2e-32 112.2 72.8 5.2e-10 39.8 8.3 5.2 2 1 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella WW PF00397.26 EGB11662.1 - 4.1e-06 26.8 0.0 8.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 WW domain Dockerin_1 PF00404.18 EGB11662.1 - 1.2e-05 25.4 24.3 2 8.7 0.1 6.2 6 0 0 6 6 6 4 Dockerin type I domain DUF3927 PF13064.6 EGB11662.1 - 0.015 15.3 1.5 0.16 11.9 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3927) AbfS_sensor PF18225.1 EGB11662.1 - 0.019 14.8 0.1 10 6.1 0.0 4.2 6 0 0 6 6 6 0 Sensor histidine kinase (AbfS) sensor domain vWF_A PF12450.8 EGB11662.1 - 0.075 13.0 7.8 34 4.5 0.1 5.4 6 0 0 6 6 6 0 von Willebrand factor Hydrolase_4 PF12146.8 EGB11662.1 - 0.18 11.0 2.1 1.8 7.7 0.2 3.0 3 1 0 3 3 3 0 Serine aminopeptidase, S33 SKN1 PF03935.15 EGB11663.1 - 3.7e-59 200.5 1.9 4.7e-50 170.4 1.1 3.5 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 EGB11663.1 - 4.7e-08 32.7 0.2 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 CRAL_TRIO PF00650.20 EGB11663.1 - 1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain SET PF00856.28 EGB11664.1 - 0.00059 20.3 0.0 0.00059 20.3 0.0 4.7 3 2 1 4 4 4 1 SET domain Cupin_8 PF13621.6 EGB11665.1 - 1.9e-18 67.1 0.0 3.3e-09 36.8 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 EGB11665.1 - 1.6e-10 40.9 0.1 3.1e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EGB11665.1 - 0.024 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain EF-hand_8 PF13833.6 EGB11666.1 - 1.4e-15 56.8 0.1 0.00015 21.5 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGB11666.1 - 2.6e-14 51.9 3.9 0.00063 19.5 0.1 5.8 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.6 EGB11666.1 - 3.8e-13 49.7 0.0 0.018 15.5 0.0 4.9 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 EGB11666.1 - 6.1e-13 47.3 7.4 0.0011 18.4 0.2 5.9 6 0 0 6 6 6 3 EF hand EF-hand_5 PF13202.6 EGB11666.1 - 3.9e-10 38.8 4.1 0.0014 18.1 0.1 3.6 3 0 0 3 3 3 3 EF hand CpeS PF09367.10 EGB11666.1 - 0.031 14.2 0.0 4.5 7.2 0.0 2.7 3 0 0 3 3 3 0 CpeS-like protein Ribosomal_L20 PF00453.18 EGB11666.1 - 0.05 13.7 0.0 29 4.8 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein L20 SPARC_Ca_bdg PF10591.9 EGB11666.1 - 0.05 13.9 0.0 4.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region RasGEF_N_2 PF14663.6 EGB11666.1 - 0.24 11.8 0.0 38 4.7 0.0 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain LBR_tudor PF09465.10 EGB11666.1 - 0.39 10.6 0.9 98 2.9 0.1 3.2 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain Pkinase PF00069.25 EGB11667.1 - 7.1e-61 205.9 0.0 8.6e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11667.1 - 1.1e-29 103.6 0.0 1.3e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGB11667.1 - 0.006 15.6 0.2 0.012 14.6 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Redoxin PF08534.10 EGB11668.1 - 4.2e-25 88.2 0.0 7.6e-25 87.3 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGB11668.1 - 9.8e-08 32.0 0.0 1.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family SNF2_N PF00176.23 EGB11669.1 - 6.6e-35 120.5 0.0 7.4e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Anth_Ig PF05587.13 EGB11669.1 - 0.033 14.5 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Anthrax receptor extracellular domain Helicase_C PF00271.31 EGB11670.1 - 0.021 15.2 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Fer2 PF00111.27 EGB11671.1 - 1.8e-09 37.4 0.3 2.4e-09 37.0 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Barstar PF01337.18 EGB11671.1 - 0.12 12.4 0.0 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 Barstar (barnase inhibitor) DnaJ PF00226.31 EGB11672.1 - 1e-08 35.2 0.1 1.7e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain zf-MYND PF01753.18 EGB11672.1 - 1.7e-07 31.2 14.0 4.9e-07 29.7 14.0 1.8 1 0 0 1 1 1 1 MYND finger TPR_17 PF13431.6 EGB11672.1 - 0.00013 22.1 0.2 1.2 9.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11672.1 - 0.0013 18.5 8.7 0.033 14.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11672.1 - 0.028 14.5 28.3 0.09 12.9 0.0 7.2 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB11672.1 - 0.03 14.0 4.6 1.2 8.8 0.2 4.0 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 EGB11672.1 - 0.14 12.5 3.3 3.5 8.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 EGB11673.1 - 4.1e-28 98.3 0.0 6.4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGB11673.1 - 8.5e-25 87.3 0.0 1.8e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB11673.1 - 1.7e-05 24.9 0.0 3.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_88 PF07470.13 EGB11674.1 - 3.1e-11 43.0 0.3 1.1e-10 41.1 0.1 2.0 2 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 Trypan_PARP PF05887.11 EGB11674.1 - 0.38 10.7 11.0 0.79 9.7 11.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_6 PF12774.7 EGB11675.1 - 9.8e-156 517.7 0.1 2.1e-154 513.4 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB11675.1 - 3.4e-123 411.7 0.0 3.4e-123 411.7 0.0 2.8 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGB11675.1 - 8.6e-100 333.9 0.3 1.3e-98 330.0 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGB11675.1 - 6.9e-99 330.4 0.0 1.8e-98 329.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGB11675.1 - 7.2e-87 290.1 1.2 2.5e-86 288.4 0.3 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGB11675.1 - 3.4e-70 235.2 0.0 5.8e-69 231.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGB11675.1 - 2e-54 183.8 0.0 4.2e-53 179.5 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGB11675.1 - 9.2e-42 141.9 0.1 8.1e-41 138.9 0.0 2.7 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGB11675.1 - 6.1e-38 130.7 11.6 6.1e-38 130.7 11.6 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EGB11675.1 - 3.6e-27 95.0 0.0 3.4e-26 91.8 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGB11675.1 - 4.9e-14 52.4 0.0 2e-13 50.4 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB11675.1 - 1.7e-08 34.6 0.0 0.25 11.3 0.0 5.5 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EGB11675.1 - 0.00092 19.6 0.9 4.4 7.7 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGB11675.1 - 0.014 15.8 0.0 15 6.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 EGB11675.1 - 0.015 15.7 2.6 15 5.9 0.0 5.4 5 0 0 5 5 4 0 AAA ATPase domain AAA_18 PF13238.6 EGB11675.1 - 0.036 14.6 3.3 8.2 7.0 0.0 4.8 5 0 0 5 5 4 0 AAA domain KIP1 PF07765.12 EGB11675.1 - 0.038 14.1 2.1 0.63 10.2 1.5 3.3 2 0 0 2 2 2 0 KIP1-like protein KinB_sensor PF16767.5 EGB11675.1 - 0.16 12.5 3.7 0.19 12.2 0.7 2.7 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB AAA_22 PF13401.6 EGB11675.1 - 0.18 12.1 3.6 1.4 9.2 0.1 3.6 3 0 0 3 3 3 0 AAA domain Fzo_mitofusin PF04799.13 EGB11675.1 - 1.6 8.3 10.3 25 4.4 1.3 4.0 3 0 0 3 3 3 0 fzo-like conserved region DUF1664 PF07889.12 EGB11675.1 - 3.9 7.5 20.4 4.9 7.2 1.7 4.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Plasmid_RAQPRD PF09686.10 EGB11675.1 - 8.2 6.7 12.3 9.7 6.5 0.0 5.2 5 0 0 5 5 5 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Ank_2 PF12796.7 EGB11676.1 - 1.7e-31 108.7 1.8 2.6e-12 47.1 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB11676.1 - 2.2e-28 97.9 11.0 1.6e-07 31.5 0.3 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB11676.1 - 8.7e-27 93.1 1.2 1.9e-10 41.0 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11676.1 - 1.1e-23 80.6 3.3 0.0025 18.2 0.0 5.5 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EGB11676.1 - 4.1e-23 80.8 16.1 3e-06 27.4 0.0 5.4 5 1 1 6 6 6 5 Ankyrin repeat VCBS PF13517.6 EGB11677.1 - 7e-107 350.0 245.7 1.4e-10 41.6 7.5 24.7 9 6 15 24 24 24 23 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PT PF04886.12 EGB11677.1 - 0.00065 19.2 22.8 0.00065 19.2 22.8 16.5 10 5 3 13 13 13 3 PT repeat TPR_12 PF13424.6 EGB11678.1 - 0.18 12.1 13.4 0.77 10.1 8.2 3.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11678.1 - 1.2 9.4 20.2 1.3 9.3 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 EGB11679.1 - 2.3e-36 124.8 0.0 3.3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGB11679.1 - 4.1e-27 94.5 0.1 5.4e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Pacifastin_I PF05375.13 EGB11680.1 - 0.00023 20.8 8.0 0.00052 19.7 7.2 2.0 1 1 1 2 2 2 1 Pacifastin inhibitor (LCMII) Glyco_transf_4 PF13439.6 EGB11680.1 - 0.0078 16.2 2.4 0.0078 16.2 2.4 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Sulfotransfer_3 PF13469.6 EGB11680.1 - 0.02 15.3 0.7 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 Sulfotransferase family Thioredoxin PF00085.20 EGB11681.1 - 1.2e-09 38.1 0.1 1.3e-09 38.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGB11681.1 - 0.017 14.5 0.1 0.018 14.4 0.1 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGB11681.1 - 0.097 13.1 0.0 0.097 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain zf-RING_2 PF13639.6 EGB11682.1 - 1e-10 41.8 7.5 2e-10 40.8 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGB11682.1 - 1.1e-09 38.0 5.1 1.8e-09 37.3 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB11682.1 - 1.1e-09 37.9 8.2 1.9e-09 37.2 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB11682.1 - 7.3e-09 35.4 7.3 1.4e-08 34.5 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB11682.1 - 2.2e-07 30.7 5.3 4.7e-07 29.7 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB11682.1 - 1.9e-06 27.8 6.3 4.5e-06 26.6 6.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGB11682.1 - 2.8e-06 27.1 7.0 5.2e-06 26.2 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGB11682.1 - 0.00028 21.1 5.9 0.001 19.3 5.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EGB11682.1 - 0.00036 20.6 3.2 0.00091 19.3 3.2 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EGB11682.1 - 0.0075 16.0 2.9 0.022 14.5 2.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGB11682.1 - 0.01 15.9 9.0 0.021 15.0 9.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGB11682.1 - 0.024 14.4 4.5 0.05 13.4 4.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TEX13 PF15186.6 EGB11682.1 - 0.042 13.5 0.3 0.042 13.5 0.3 2.4 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Laminin_II PF06009.12 EGB11682.1 - 0.59 10.1 2.9 0.29 11.2 0.3 1.8 2 0 0 2 2 2 0 Laminin Domain II PMAIP1 PF15150.6 EGB11682.1 - 0.69 9.8 2.7 2.8 7.9 0.5 2.8 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced zf-P11 PF03854.14 EGB11682.1 - 0.84 9.3 5.7 3.6 7.3 5.7 1.8 1 1 0 1 1 1 0 P-11 zinc finger COG2 PF06148.11 EGB11682.1 - 2.7 8.1 4.1 0.86 9.7 0.1 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Dscam_C PF12355.8 EGB11683.1 - 0.045 14.7 0.4 0.069 14.1 0.4 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal PRIMA1 PF16101.5 EGB11683.1 - 0.17 11.9 4.8 0.25 11.4 4.8 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EGB11683.1 - 0.27 10.7 2.8 0.38 10.2 2.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PH PF00169.29 EGB11684.1 - 1.2e-10 41.8 0.4 7.1e-06 26.5 0.1 2.6 2 0 0 2 2 2 2 PH domain C2 PF00168.30 EGB11684.1 - 6.1e-09 36.1 0.0 7e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 C2 domain PH_17 PF18012.1 EGB11684.1 - 0.0088 15.7 0.1 0.025 14.3 0.1 1.8 1 0 0 1 1 1 1 PH domain PRT_C PF08372.10 EGB11684.1 - 0.037 13.8 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal PH_11 PF15413.6 EGB11684.1 - 0.19 12.1 6.1 0.34 11.4 0.6 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain DUF2273 PF10031.9 EGB11684.1 - 7.5 6.6 9.6 0.38 10.8 0.5 2.5 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Exo_endo_phos PF03372.23 EGB11685.1 - 7.2e-06 25.7 0.0 2.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ras PF00071.22 EGB11686.1 - 1.3e-54 184.1 0.1 1.6e-54 183.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB11686.1 - 1.3e-30 106.0 0.1 1.9e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB11686.1 - 1.7e-13 50.4 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGB11686.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGB11686.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGB11686.1 - 0.0057 16.0 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 EGB11686.1 - 0.033 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 EGB11686.1 - 0.041 13.6 0.1 0.089 12.5 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EGB11686.1 - 0.062 12.8 0.4 0.26 10.8 0.4 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MCM PF00493.23 EGB11686.1 - 0.073 12.2 0.4 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain G-alpha PF00503.20 EGB11686.1 - 0.097 11.8 2.7 2.3 7.3 0.6 2.1 1 1 1 2 2 2 0 G-protein alpha subunit LapA_dom PF06305.11 EGB11687.1 - 0.047 13.5 0.3 0.092 12.6 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MCD_N PF17408.2 EGB11689.1 - 0.87 9.8 9.9 0.57 10.4 0.3 3.6 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain NAD_binding_1 PF00175.21 EGB11690.1 - 6.7e-25 87.9 0.0 1.2e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 EGB11690.1 - 0.015 14.9 0.0 3.1 7.3 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain FAD_binding_6 PF00970.24 EGB11690.1 - 0.069 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain LSM PF01423.22 EGB11691.1 - 1.6e-16 59.7 0.0 2.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGB11691.1 - 0.00013 22.0 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGB11691.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain ArfGap PF01412.18 EGB11692.1 - 8.1e-26 90.4 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 EGB11692.1 - 2.9e-08 34.2 0.1 7.2e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB11692.1 - 3e-05 24.5 0.4 0.025 15.2 0.2 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB11692.1 - 3.9e-05 23.8 1.4 0.00021 21.5 0.5 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11692.1 - 0.0009 19.5 0.3 0.027 15.0 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EGB11692.1 - 0.0012 19.2 1.5 0.11 13.0 0.4 3.1 3 0 0 3 3 3 1 Ankyrin repeat zf-dskA_traR PF01258.17 EGB11692.1 - 2.8 8.0 5.7 2.8 7.9 0.8 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DnaJ PF00226.31 EGB11693.1 - 7.1e-28 96.5 0.9 7.8e-28 96.4 0.9 1.0 1 0 0 1 1 1 1 DnaJ domain Gp-FAR-1 PF05823.12 EGB11693.1 - 0.068 13.5 0.1 0.076 13.4 0.1 1.0 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) RCC1 PF00415.18 EGB11694.1 - 6.9e-60 199.5 34.4 2.6e-14 53.6 0.2 7.4 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB11694.1 - 2.9e-27 93.8 52.1 8.1e-09 35.1 3.5 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Reg_prop PF07494.11 EGB11694.1 - 0.019 15.1 0.2 1.1e+02 3.5 0.0 4.8 5 0 0 5 5 5 0 Two component regulator propeller SUKH-3 PF14433.6 EGB11694.1 - 0.2 12.1 0.6 3.6 8.0 0.0 2.6 2 1 1 3 3 3 0 SUKH-3 immunity protein DUF4821 PF16092.5 EGB11695.1 - 1.1e-76 258.0 0.0 1.7e-75 254.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 EGB11695.1 - 0.0016 17.7 4.2 0.012 14.9 0.9 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trypsin_2 PF13365.6 EGB11696.1 - 1.2e-31 110.7 3.0 1.2e-31 110.7 3.0 2.8 3 1 0 3 3 3 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGB11696.1 - 9.3e-15 55.0 0.3 1.8e-14 54.1 0.1 1.5 2 0 0 2 2 2 1 Trypsin PDZ_2 PF13180.6 EGB11696.1 - 6.4e-10 39.2 0.1 1.7e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 PDZ domain SHS2_Rpb7-N PF03876.17 EGB11696.1 - 3.1e-06 27.5 0.0 9.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 EGB11696.1 - 4.6e-05 24.0 3.0 8e-05 23.3 0.0 2.7 2 1 1 3 3 3 1 RPA43 OB domain in RNA Pol I PDZ_6 PF17820.1 EGB11696.1 - 0.00033 20.4 2.1 0.001 18.9 0.1 2.7 3 0 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 EGB11696.1 - 0.0023 17.8 0.0 0.049 13.6 0.1 2.6 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S32 PF05579.13 EGB11696.1 - 0.0072 15.6 1.9 0.22 10.7 0.2 2.4 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 SAP PF02037.27 EGB11696.1 - 0.11 12.3 0.4 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 SAP domain Presenilin PF01080.17 EGB11696.1 - 0.49 9.1 3.0 0.76 8.5 3.0 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S46 PF10459.9 EGB11696.1 - 3 6.4 19.0 0.083 11.5 0.1 2.3 2 0 0 2 2 2 0 Peptidase S46 Trypsin_2 PF13365.6 EGB11697.1 - 4.4e-33 115.3 3.0 7.4e-33 114.6 3.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGB11697.1 - 5.7e-16 59.0 0.2 8.3e-16 58.5 0.2 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EGB11697.1 - 4.8e-11 42.8 0.2 1.4e-10 41.3 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGB11697.1 - 6.4e-06 25.9 2.1 0.00015 21.5 0.1 3.2 3 0 0 3 3 3 1 PDZ domain Peptidase_S32 PF05579.13 EGB11697.1 - 0.00024 20.4 1.3 0.051 12.8 0.2 2.2 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Tricorn_PDZ PF14685.6 EGB11697.1 - 0.0024 17.8 1.3 0.0059 16.6 0.1 2.1 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 EGB11697.1 - 0.0084 14.8 0.9 0.014 14.1 0.2 1.5 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S29 PF02907.15 EGB11697.1 - 0.012 15.4 0.2 0.1 12.3 0.1 2.4 1 1 1 3 3 3 0 Hepatitis C virus NS3 protease PDZ PF00595.24 EGB11697.1 - 0.035 14.5 0.0 0.16 12.3 0.0 2.3 1 1 0 1 1 1 0 PDZ domain DOMON PF03351.17 EGB11697.1 - 0.071 13.3 0.0 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 DOMON domain SNF2_N PF00176.23 EGB11699.1 - 6.6e-25 87.6 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB11699.1 - 4.2e-12 46.4 0.0 1.5e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB11699.1 - 1e-06 28.9 0.0 9e-06 25.8 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB11699.1 - 0.00037 20.3 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGB11699.1 - 0.0035 16.6 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DAHP_synth_1 PF00793.20 EGB11699.1 - 0.034 13.0 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 DAHP synthetase I family DUF2075 PF09848.9 EGB11699.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) tRNA_anti_2 PF13742.6 EGB11699.1 - 0.17 12.1 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DnaJ PF00226.31 EGB11700.1 - 5.3e-17 61.7 0.0 6e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain PUA_3 PF17785.1 EGB11701.1 - 1.9e-16 59.6 0.0 4.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 PUA-like domain Methyltrans_SAM PF10672.9 EGB11701.1 - 3.3e-15 56.0 0.0 4.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 EGB11701.1 - 2.8e-13 49.9 0.0 4.2e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB11701.1 - 2.2e-10 41.1 0.0 9e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGB11701.1 - 1.7e-09 37.5 0.0 2.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGB11701.1 - 5.6e-08 32.5 0.1 8.8e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EGB11701.1 - 5.7e-08 32.6 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EGB11701.1 - 7.8e-05 23.3 0.1 0.00036 21.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 EGB11701.1 - 0.0002 21.1 0.1 0.00064 19.5 0.1 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 EGB11701.1 - 0.00086 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PUA PF01472.20 EGB11701.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 PUA domain Methyltransf_15 PF09445.10 EGB11701.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 EGB11701.1 - 0.26 10.4 0.2 0.74 8.9 0.2 1.6 1 1 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FKBP_C PF00254.28 EGB11702.1 - 1.4e-19 70.2 0.0 2.6e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ubiq-assoc PF09145.10 EGB11703.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-associated NDUF_B4 PF07225.12 EGB11703.1 - 0.12 12.3 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Amidohydro_1 PF01979.20 EGB11704.1 - 2.5e-74 250.7 1.1 3.8e-74 250.1 1.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EGB11704.1 - 7e-52 174.9 5.1 5.7e-51 171.9 2.8 2.4 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 EGB11704.1 - 2.5e-41 140.0 1.2 1e-40 138.0 0.1 2.4 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 EGB11704.1 - 1.6e-36 124.3 0.0 3.3e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 EGB11704.1 - 6.6e-08 32.5 2.1 1.2e-06 28.3 0.1 2.6 2 1 1 3 3 3 1 Amidohydrolase family DnaJ PF00226.31 EGB11705.1 - 4.7e-26 90.7 0.1 8.5e-26 89.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGB11705.1 - 0.03 14.2 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein Arm PF00514.23 EGB11706.1 - 1.3e-37 126.7 14.9 1.9e-07 30.9 0.2 6.8 7 1 0 7 7 7 6 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EGB11706.1 - 0.00036 20.1 0.0 0.081 12.4 0.0 2.4 2 0 0 2 2 2 2 Armadillo-like HEAT_EZ PF13513.6 EGB11706.1 - 0.00039 20.9 20.3 0.22 12.1 0.4 5.3 2 1 5 7 7 7 3 HEAT-like repeat KAP PF05804.12 EGB11706.1 - 0.0013 17.0 0.0 0.082 11.0 0.0 2.4 1 1 2 3 3 3 3 Kinesin-associated protein (KAP) HEAT_2 PF13646.6 EGB11706.1 - 0.019 15.4 17.8 0.081 13.3 2.4 4.1 1 1 4 5 5 5 0 HEAT repeats Methyltransf_11 PF08241.12 EGB11707.1 - 1.7e-10 41.4 0.1 5.6e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB11707.1 - 6.5e-06 26.8 0.2 3.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB11707.1 - 0.00019 21.3 0.0 0.00051 19.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB11707.1 - 0.0005 20.8 0.0 0.0044 17.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB11707.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB11707.1 - 0.0034 16.8 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGB11707.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CDO_I PF05995.12 EGB11707.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I DHBP_synthase PF00926.19 EGB11708.1 - 4.2e-77 258.0 0.0 5.6e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 EGB11708.1 - 6.3e-59 198.2 0.0 8.6e-59 197.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Zip PF02535.22 EGB11709.1 - 2.1e-32 112.6 0.0 3.2e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3938 PF13074.6 EGB11709.1 - 0.0045 17.2 1.3 0.018 15.2 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3938) FAD_binding_7 PF03441.14 EGB11710.1 - 2.6e-51 174.0 4.8 2.8e-51 173.9 4.8 1.0 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase APOC4 PF15119.6 EGB11710.1 - 0.014 15.6 0.5 0.029 14.6 0.5 1.5 1 0 0 1 1 1 0 Apolipoprotein C4 Ion_trans_2 PF07885.16 EGB11711.1 - 1e-10 41.4 2.9 1.6e-10 40.8 2.9 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB11711.1 - 0.014 14.6 1.0 0.021 14.0 1.0 1.2 1 0 0 1 1 1 0 Ion transport protein UBM PF14377.6 EGB11711.1 - 0.028 13.8 1.0 0.051 13.0 1.0 1.4 1 0 0 1 1 1 0 Ubiquitin binding region DUF4366 PF14283.6 EGB11713.1 - 0.096 12.7 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.21 EGB11713.1 - 0.099 12.6 0.5 0.34 10.9 0.5 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Na_Ca_ex PF01699.24 EGB11714.1 - 8.5e-48 162.1 34.7 5e-24 85.0 9.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_1 PF00036.32 EGB11714.1 - 2.9e-16 57.7 2.2 0.0002 20.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGB11714.1 - 2.9e-16 59.7 0.5 1.4e-10 41.5 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB11714.1 - 1.2e-14 52.8 2.0 4.7e-05 23.0 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EGB11714.1 - 4.9e-13 47.9 5.8 0.00063 19.1 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGB11714.1 - 1.9e-07 30.8 2.2 0.0038 17.0 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB11714.1 - 0.0079 16.5 0.0 3.5 8.0 0.1 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGB11714.1 - 0.062 13.6 0.0 0.71 10.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain MadL PF03817.13 EGB11714.1 - 2.7 8.0 8.5 1.8 8.6 1.6 2.6 2 0 0 2 2 2 0 Malonate transporter MadL subunit Voltage_CLC PF00654.20 EGB11715.1 - 4.7e-82 276.1 28.8 4.5e-81 272.9 24.5 2.7 2 1 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 EGB11715.1 - 5.5e-12 46.0 0.0 2.2e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain Phage_holin_2_1 PF04971.12 EGB11715.1 - 0.12 12.3 1.6 0.47 10.5 1.6 2.0 1 0 0 1 1 1 0 Bacteriophage P21 holin S Aldedh PF00171.22 EGB11717.1 - 3.4e-86 289.6 0.3 4.3e-86 289.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M24 PF00557.24 EGB11718.1 - 3.1e-53 180.6 0.0 4e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGB11718.1 - 8.7e-22 77.2 0.0 1.6e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fer2 PF00111.27 EGB11719.1 - 6.2e-20 70.9 1.1 7.6e-20 70.7 1.1 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EGB11719.1 - 0.059 13.4 0.1 0.06 13.4 0.1 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain ArabFuran-catal PF09206.11 EGB11720.1 - 1.8e-126 421.7 9.6 2.1e-126 421.6 9.6 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic Ank_4 PF13637.6 EGB11721.1 - 1.6e-21 76.3 4.9 1.3e-12 47.9 0.4 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11721.1 - 3.9e-19 69.0 2.0 3e-14 53.4 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Methyltransf_16 PF10294.9 EGB11721.1 - 2.4e-17 63.2 0.0 4.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ank_5 PF13857.6 EGB11721.1 - 2.1e-16 59.7 2.3 2.1e-08 34.2 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB11721.1 - 7.6e-13 48.3 1.2 5e-07 29.9 0.4 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB11721.1 - 1e-10 40.9 1.0 3.5e-05 23.9 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Methyltransf_25 PF13649.6 EGB11721.1 - 0.0018 18.9 0.3 0.0071 17.0 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB11721.1 - 0.0032 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGB11721.1 - 0.013 16.1 0.4 0.047 14.3 0.4 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB11721.1 - 0.059 14.1 0.0 0.23 12.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain TPR_12 PF13424.6 EGB11722.1 - 5.5e-42 141.9 74.6 9.7e-09 35.4 7.1 10.4 8 3 1 11 11 11 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11722.1 - 1.1e-29 101.5 58.4 0.00016 21.4 1.5 13.1 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11722.1 - 2.7e-06 27.0 44.3 0.2 11.8 0.1 10.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11722.1 - 2.2e-05 24.3 20.0 1.3 9.4 0.1 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11722.1 - 2.7e-05 23.9 54.4 0.017 15.2 1.3 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11722.1 - 5.4e-05 22.8 35.0 0.21 11.5 0.3 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 EGB11722.1 - 0.0059 16.8 3.7 0.033 14.4 3.7 2.4 1 0 0 1 1 1 1 ABC transporter C-terminal domain TPR_17 PF13431.6 EGB11722.1 - 0.39 11.2 21.0 19 5.9 0.2 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Ank_4 PF13637.6 EGB11723.1 - 1.2e-35 121.4 8.5 1.1e-11 45.0 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11723.1 - 1.3e-30 105.8 0.9 1.8e-10 41.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGB11723.1 - 7.6e-29 98.9 7.3 1.6e-06 28.3 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EGB11723.1 - 1.8e-27 95.0 8.3 7e-09 35.8 0.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11723.1 - 5e-25 84.8 1.9 0.00031 21.0 0.1 5.6 6 0 0 6 6 6 5 Ankyrin repeat Inhibitor_I29 PF08246.12 EGB11724.1 - 6.3e-11 42.6 0.0 9.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Apolipoprotein PF01442.18 EGB11724.1 - 0.001 19.0 20.9 0.001 19.0 20.9 5.1 2 1 2 4 4 4 2 Apolipoprotein A1/A4/E domain Stomoxyn PF11585.8 EGB11725.1 - 0.14 12.2 1.1 0.33 11.0 1.1 1.7 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn cNMP_binding PF00027.29 EGB11726.1 - 5.1e-15 55.3 0.0 1e-14 54.4 0.1 1.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Cyclotide PF03784.13 EGB11726.1 - 0.94 9.6 4.5 1.7 8.8 4.4 1.5 1 1 0 1 1 1 0 Cyclotide family Bax1-I PF01027.20 EGB11727.1 - 4.2e-07 30.0 3.7 5.1e-07 29.7 3.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 GTP-bdg_N PF13167.6 EGB11728.1 - 7.4e-23 81.0 0.2 2.4e-22 79.4 0.2 1.9 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 EGB11728.1 - 2.4e-21 76.1 4.2 5e-21 75.1 4.2 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 EGB11728.1 - 7.7e-16 58.2 0.0 1.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGB11728.1 - 0.0052 16.3 0.0 0.56 9.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGB11728.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EGB11728.1 - 0.027 14.5 0.0 0.09 12.8 0.0 1.8 1 1 1 2 2 2 0 Dynamin family AAA_28 PF13521.6 EGB11728.1 - 0.049 13.9 0.3 11 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGB11728.1 - 0.065 13.6 2.6 0.24 11.8 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 EGB11728.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SRPRB PF09439.10 EGB11728.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EGB11728.1 - 0.17 11.7 0.0 0.79 9.4 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 EGB11728.1 - 0.21 12.1 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain IRK_C PF17655.1 EGB11729.1 - 8.8e-24 84.0 0.0 1.2e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 EGB11729.1 - 3.5e-16 59.3 11.8 4.2e-14 52.6 11.8 2.2 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 EGB11729.1 - 0.078 12.9 7.4 0.19 11.7 7.4 1.8 1 1 0 1 1 1 0 Ion channel PHD_2 PF13831.6 EGB11729.1 - 0.24 11.0 0.9 12 5.6 0.2 2.5 2 0 0 2 2 2 0 PHD-finger Beach PF02138.18 EGB11730.1 - 3.6e-95 318.5 0.0 9.1e-95 317.2 0.0 1.6 1 1 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGB11730.1 - 6.8e-15 55.0 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Beach PF02138.18 EGB11731.1 - 6.3e-17 61.9 0.0 8.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGB11731.1 - 5e-15 55.4 0.0 9.2e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Aldo_ket_red PF00248.21 EGB11732.1 - 2.2e-29 102.6 0.0 1.6e-27 96.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 EGB11733.1 - 2e-30 106.0 0.0 2.3e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11733.1 - 1e-19 70.9 0.0 1.1e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB11733.1 - 1.2e-05 24.8 0.0 2.3e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGB11733.1 - 0.0011 17.9 0.1 0.0013 17.6 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB11733.1 - 0.033 14.1 0.3 0.053 13.4 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGB11733.1 - 0.069 12.2 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 EGB11735.1 - 5.5e-28 98.0 0.0 6.5e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11735.1 - 1.5e-26 93.3 0.0 1.7e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB11735.1 - 0.0048 16.3 0.0 0.019 14.3 0.0 1.9 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB11735.1 - 0.0051 16.8 0.2 0.006 16.5 0.2 1.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB11735.1 - 0.092 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like cNMP_binding PF00027.29 EGB11736.1 - 3.3e-13 49.5 0.1 1.1e-12 47.8 0.1 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB11736.1 - 4e-09 36.1 13.5 9.1e-09 34.9 13.5 1.6 1 1 0 1 1 1 1 Ion transport protein HK PF02110.15 EGB11736.1 - 0.057 12.8 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family ASFV_L11L PF05293.11 EGB11736.1 - 1.4 9.3 6.2 0.49 10.8 0.6 3.0 3 0 0 3 3 3 0 African swine fever virus (ASFV) L11L protein FAM184 PF15665.5 EGB11737.1 - 5e-53 180.0 37.4 5e-53 180.0 37.4 6.6 1 1 2 5 5 5 2 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 EGB11737.1 - 0.0053 16.8 0.1 0.0053 16.8 0.1 7.0 6 2 3 9 9 9 1 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 EGB11737.1 - 0.0072 16.4 5.4 0.0072 16.4 5.4 11.7 2 1 10 14 14 14 3 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 EGB11737.1 - 0.07 13.2 0.1 0.07 13.2 0.1 8.3 5 2 2 7 7 7 0 TolA binding protein trimerisation DUF2895 PF11444.8 EGB11738.1 - 0.24 10.8 1.2 0.4 10.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Kinesin PF00225.23 EGB11739.1 - 1.5e-87 293.7 0.0 1.7e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB11739.1 - 8.9e-16 58.2 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 EGB11739.1 - 0.23 11.3 0.2 0.4 10.5 0.2 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein Kinesin PF00225.23 EGB11740.1 - 8.2e-24 84.1 0.0 9.3e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB11740.1 - 3.9e-11 43.1 0.0 4.3e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 EGB11740.1 - 0.029 14.2 0.1 0.038 13.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein Sacchrp_dh_NADP PF03435.18 EGB11741.1 - 2.9e-13 50.2 0.5 5.8e-13 49.2 0.5 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGB11741.1 - 2.1e-06 27.7 2.3 3.2e-06 27.1 2.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Pkinase PF00069.25 EGB11742.1 - 1.8e-36 125.9 0.0 2e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11742.1 - 4.1e-19 68.9 0.0 4.6e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB11742.1 - 6.2e-07 29.6 0.3 1.3e-06 28.5 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB11742.1 - 0.00022 20.6 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB11742.1 - 0.0026 17.2 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGB11742.1 - 0.043 12.7 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Aa_trans PF01490.18 EGB11743.1 - 6.9e-36 123.8 18.2 8.5e-36 123.5 18.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sel1 PF08238.12 EGB11744.1 - 6.3e-21 74.4 11.2 1.6e-06 28.6 0.2 4.7 5 0 0 5 5 5 4 Sel1 repeat Fis1_TPR_N PF14852.6 EGB11744.1 - 0.0011 18.6 0.2 0.12 12.0 0.0 2.9 3 0 0 3 3 3 1 Fis1 N-terminal tetratricopeptide repeat TPR_12 PF13424.6 EGB11744.1 - 0.0093 16.2 1.4 17 5.8 0.0 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11744.1 - 0.058 14.1 7.0 1.5 9.6 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB11744.1 - 0.082 13.3 2.1 20 5.8 0.1 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11744.1 - 0.19 11.6 4.4 7.2 6.6 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11744.1 - 0.19 12.4 5.4 4.1 8.1 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 EGB11745.1 - 3.7e-27 95.4 4.6 8.9e-15 54.7 0.0 3.0 1 1 0 2 2 2 2 Subtilase family Kringle PF00051.18 EGB11745.1 - 9.3e-19 67.5 5.4 4.5e-18 65.3 5.4 2.3 1 0 0 1 1 1 1 Kringle domain P_proprotein PF01483.20 EGB11745.1 - 8.1e-09 35.4 0.1 3e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Proprotein convertase P-domain Glyco_trans_1_2 PF13524.6 EGB11746.1 - 0.0028 18.0 0.8 0.014 15.8 0.1 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.6 EGB11746.1 - 0.014 15.3 2.2 0.024 14.5 0.2 2.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Redoxin PF08534.10 EGB11748.1 - 1.5e-20 73.4 0.0 1.8e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGB11748.1 - 0.0002 21.2 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family TPR_2 PF07719.17 EGB11749.1 - 1.4e-08 34.2 11.9 0.00079 19.4 1.7 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11749.1 - 2.8e-07 30.0 9.0 0.012 15.4 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11749.1 - 1.2e-06 29.1 19.4 8.4e-05 23.1 8.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB11749.1 - 2.4e-05 24.4 10.6 0.013 15.6 2.6 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11749.1 - 0.0007 19.5 1.7 0.74 10.0 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB11749.1 - 0.00078 20.1 13.5 0.025 15.4 2.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11749.1 - 0.0017 18.4 1.9 0.049 13.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11749.1 - 0.0017 18.8 11.8 0.017 15.6 1.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11749.1 - 0.016 15.5 6.3 1.2 9.5 1.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB11749.1 - 0.036 13.8 5.7 0.036 13.8 5.7 3.2 2 2 1 3 3 3 0 TPR repeat Gln_amidase PF15644.6 EGB11749.1 - 0.044 14.8 0.2 0.076 14.0 0.2 1.4 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase TPR_6 PF13174.6 EGB11749.1 - 0.049 14.3 3.2 3 8.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPM_phosphatase PF04536.14 EGB11749.1 - 0.084 13.0 0.1 0.96 9.6 0.0 2.1 2 0 0 2 2 2 0 TPM domain DUF3856 PF12968.7 EGB11749.1 - 0.085 12.9 1.1 1.2 9.2 0.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) ArsR PF09824.9 EGB11749.1 - 0.22 11.1 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator 2OG-FeII_Oxy PF03171.20 EGB11750.1 - 4.5e-19 68.8 0.0 1e-18 67.6 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGB11750.1 - 2.2e-17 63.9 0.0 3.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ser_hydrolase PF06821.13 EGB11751.1 - 1.4e-07 31.6 0.1 3.3e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 EGB11751.1 - 9.1e-05 23.2 7.3 0.00014 22.5 7.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB11751.1 - 0.0019 17.9 0.0 0.0058 16.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGB11751.1 - 0.0064 16.3 0.0 0.039 13.8 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1057 PF06342.12 EGB11751.1 - 0.0078 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Sulfate_transp PF00916.20 EGB11752.1 - 7e-30 104.0 13.8 2e-18 66.4 6.2 2.2 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 EGB11752.1 - 0.002 17.7 0.0 0.0041 16.7 0.0 1.5 1 1 0 1 1 1 1 STAS domain Nop53 PF07767.11 EGB11753.1 - 1.4 8.2 26.5 1.8 7.8 26.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF913 PF06025.12 EGB11753.1 - 2.4 7.0 5.5 7.6 5.4 3.8 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 EGB11753.1 - 4.7 6.1 9.0 6.1 5.7 9.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Aldo_ket_red PF00248.21 EGB11754.1 - 1.1e-38 133.1 0.0 1.3e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flavin_Reduct PF01613.18 EGB11754.1 - 0.075 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Flavin reductase like domain Glyoxalase PF00903.25 EGB11755.1 - 0.0086 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGB11755.1 - 0.14 12.4 0.1 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGB11755.1 - 0.19 12.6 1.4 0.42 11.4 0.2 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain GFO_IDH_MocA PF01408.22 EGB11757.1 - 5.7e-17 62.7 0.0 1.2e-16 61.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGB11757.1 - 1.7e-10 40.9 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ApbA PF02558.16 EGB11757.1 - 0.029 14.0 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glycos_transf_2 PF00535.26 EGB11758.1 - 0.00021 21.1 0.1 0.00067 19.5 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Methyltransf_21 PF05050.12 EGB11758.1 - 0.0028 17.7 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain CodY PF06018.14 EGB11758.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 CodY GAF-like domain MgtC PF02308.16 EGB11760.1 - 9.7e-33 113.1 9.7 1.1e-32 113.0 9.7 1.0 1 0 0 1 1 1 1 MgtC family UAA PF08449.11 EGB11761.1 - 6.7e-52 176.6 16.6 7.7e-52 176.4 16.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB11761.1 - 7.3e-05 23.0 13.2 7.3e-05 23.0 13.2 3.2 2 2 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 EGB11761.1 - 0.0051 16.2 2.6 0.0051 16.2 2.6 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family Thioesterase PF00975.20 EGB11763.1 - 2.9e-18 66.8 0.0 6.1e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Glyco_trans_1_2 PF13524.6 EGB11763.1 - 3e-14 53.2 0.6 7.4e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 TPR_10 PF13374.6 EGB11763.1 - 0.016 15.0 0.2 0.057 13.3 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB11763.1 - 2 9.5 7.5 6.4 7.9 1.9 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat bPH_2 PF03703.14 EGB11764.1 - 5.5e-13 48.9 0.1 6.7e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 Bacterial PH domain Lectin_legB PF00139.19 EGB11764.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Legume lectin domain 2OG-FeII_Oxy_3 PF13640.6 EGB11765.1 - 1.8e-14 54.4 0.0 4.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VHL PF01847.16 EGB11765.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 VHL beta domain MTP18 PF10558.9 EGB11766.1 - 6.1e-20 71.9 2.7 3.6e-09 36.8 0.5 2.3 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Sulfotransfer_3 PF13469.6 EGB11767.1 - 0.002 18.6 0.0 0.039 14.3 0.0 2.4 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB11767.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Ion_trans PF00520.31 EGB11768.1 - 4.2e-19 68.7 2.9 7.1e-19 68.0 2.9 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB11768.1 - 6.2e-12 45.3 2.2 1.6e-11 44.0 2.2 1.7 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.26 EGB11768.1 - 0.051 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Ligand-gated ion channel UPF0061 PF02696.14 EGB11769.1 - 3e-72 243.9 0.0 6.3e-38 130.7 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family PI3_PI4_kinase PF00454.27 EGB11770.1 - 5.4e-18 65.7 0.0 1.3e-11 44.8 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 EGB11770.1 - 0.079 13.5 0.0 0.71 10.4 0.0 2.1 2 0 0 2 2 2 0 PH domain Ribosomal_L3 PF00297.22 EGB11771.1 - 5.9e-178 591.5 8.2 6.7e-178 591.3 8.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Trehalase PF01204.18 EGB11772.1 - 4.8e-116 388.6 0.0 7e-116 388.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase MitMem_reg PF13012.6 EGB11772.1 - 6.3e-20 71.7 0.0 1.1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGB11772.1 - 2.8e-07 30.5 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf_CCCH_4 PF18345.1 EGB11772.1 - 0.00021 21.2 5.5 0.00045 20.2 5.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGB11772.1 - 0.00054 19.7 4.2 0.0011 18.7 4.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGB11772.1 - 0.00066 19.5 2.5 0.0016 18.3 2.5 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGB11772.1 - 0.023 15.4 0.9 0.044 14.5 0.9 1.3 1 0 0 1 1 1 0 Torus domain GBP PF02263.19 EGB11773.1 - 9.8e-27 93.8 0.1 1.1e-26 93.7 0.1 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Methyltransf_25 PF13649.6 EGB11774.1 - 0.00017 22.2 0.0 0.00021 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB11774.1 - 0.00038 21.0 0.0 0.00049 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PMSR PF01625.21 EGB11775.1 - 9.2e-18 64.9 0.0 1.2e-17 64.6 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Membralin PF09746.9 EGB11776.1 - 0.00018 20.7 0.2 0.086 11.9 0.2 2.2 2 0 0 2 2 2 2 Tumour-associated protein DUF2070 PF09843.9 EGB11776.1 - 0.042 12.1 5.7 0.048 11.9 5.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SAM_decarbox PF01536.16 EGB11777.1 - 9.1e-90 301.2 0.0 1.1e-89 300.9 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase AdoMet_dc PF02675.15 EGB11777.1 - 0.033 14.4 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase EF-hand_1 PF00036.32 EGB11778.1 - 3.1e-09 35.7 0.1 0.0013 18.1 0.1 2.3 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGB11778.1 - 4.2e-08 32.5 0.0 0.0034 17.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB11778.1 - 9.3e-07 29.2 0.0 1e-06 29.1 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB11778.1 - 5.1e-05 22.6 0.8 0.0011 18.4 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EGB11778.1 - 0.00013 21.7 0.2 0.0012 18.6 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGB11778.1 - 0.13 12.7 0.0 0.13 12.6 0.0 1.0 1 0 0 1 1 1 0 EF-hand domain Spherulin4 PF12138.8 EGB11779.1 - 1.3e-22 80.6 0.1 2.3e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 Spherulation-specific family 4 PhyH PF05721.13 EGB11780.1 - 1.7e-20 74.2 0.0 3.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PH PF00169.29 EGB11780.1 - 1.1e-07 32.4 0.0 2.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 PH domain 2OG-FeII_Oxy_5 PF13759.6 EGB11780.1 - 0.18 12.3 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CAP_N PF01213.19 EGB11780.1 - 0.86 9.0 4.2 1.6 8.1 4.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TPMT PF05724.11 EGB11781.1 - 4.8e-24 85.2 0.0 1.1e-23 84.1 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 EGB11781.1 - 3.4e-11 43.2 0.0 4.5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB11781.1 - 1e-10 42.2 0.0 2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB11781.1 - 1.7e-10 41.5 0.0 2.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB11781.1 - 3.5e-09 37.2 0.0 5.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB11781.1 - 1e-05 25.4 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB11781.1 - 0.00021 21.1 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EGB11781.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Sulfatase PF00884.23 EGB11782.1 - 1.3e-19 70.7 0.0 1.5e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Rad60-SLD PF11976.8 EGB11783.1 - 1.3e-16 60.2 0.5 1.4e-16 60.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGB11783.1 - 1e-11 44.4 0.2 1.1e-11 44.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Alpha_L_fucos PF01120.17 EGB11784.1 - 7.3e-37 127.6 0.0 8.9e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 EGB11784.1 - 0.025 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Pro_isomerase PF00160.21 EGB11785.1 - 7.8e-42 143.2 0.1 9.8e-42 142.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tau95_N PF17682.1 EGB11785.1 - 0.19 11.9 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Tau95 Triple barrel domain Sel1 PF08238.12 EGB11786.1 - 3.3e-43 145.1 28.0 4.7e-08 33.4 0.3 8.9 8 2 0 8 8 8 6 Sel1 repeat TPR_16 PF13432.6 EGB11786.1 - 0.00063 20.3 16.1 5.1 7.8 4.4 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF977 PF06163.11 EGB11786.1 - 0.0039 17.1 3.2 9.8 6.1 0.0 4.0 2 2 2 4 4 4 1 Bacterial protein of unknown function (DUF977) TPR_12 PF13424.6 EGB11786.1 - 0.019 15.2 13.3 0.12 12.6 0.2 5.3 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11786.1 - 0.026 14.4 12.4 0.69 9.9 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB11786.1 - 0.038 14.4 0.3 53 4.5 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11786.1 - 0.048 13.5 0.1 0.048 13.5 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Flu_M1_C PF08289.11 EGB11786.1 - 0.075 13.3 0.1 0.74 10.1 0.0 2.3 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain RHH_1 PF01402.21 EGB11786.1 - 0.082 12.9 0.7 23 5.1 0.2 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family TPR_20 PF14561.6 EGB11786.1 - 0.1 13.0 6.8 3.1 8.2 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB11786.1 - 0.64 10.5 3.5 92 3.6 0.1 4.5 4 2 2 6 6 6 0 B12 binding domain TPR_8 PF13181.6 EGB11786.1 - 1.2 9.6 0.1 1.2 9.6 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGB11786.1 - 1.3 9.1 6.3 15 5.7 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11786.1 - 5.2 7.3 9.6 13 6.1 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 EGB11787.1 - 1.3e-23 83.7 0.0 1.4e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11787.1 - 3.5e-10 39.6 0.0 3.8e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB11787.1 - 0.0035 16.2 0.0 0.0039 16.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB11787.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hexapep PF00132.24 EGB11788.1 - 2.2e-18 65.2 16.1 3.2e-09 36.2 1.7 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGB11788.1 - 3.5e-05 23.5 17.4 0.013 15.2 3.0 4.1 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase CART PF06373.11 EGB11788.1 - 1.3 9.3 4.9 0.48 10.6 0.7 2.3 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) GD_AH_C PF04295.13 EGB11789.1 - 1.4e-108 363.2 0.0 1.6e-108 363.0 0.0 1.0 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus DnaJ PF00226.31 EGB11790.1 - 5.3e-26 90.5 0.1 6.1e-26 90.3 0.1 1.0 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 EGB11791.1 - 2.4e-13 50.3 15.5 0.0036 18.1 1.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.6 EGB11791.1 - 3.8e-05 24.0 14.7 0.22 12.1 0.1 5.0 3 1 2 5 5 5 3 PQQ-like domain ANAPC4_WD40 PF12894.7 EGB11791.1 - 0.00046 20.4 0.0 3.5 8.0 0.0 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGB11791.1 - 0.0026 17.4 1.3 0.0078 15.8 0.2 2.1 2 1 0 2 2 2 1 PQQ-like domain DUF667 PF05018.13 EGB11792.1 - 5.5e-13 49.0 0.0 5.8e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DnaJ PF00226.31 EGB11793.1 - 6.8e-20 71.0 0.0 7.7e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain DtxR PF18357.1 EGB11793.1 - 0.23 11.1 0.1 0.35 10.6 0.1 1.3 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain Erv26 PF04148.13 EGB11794.1 - 1.5e-36 126.2 3.6 4.2e-36 124.7 3.6 1.6 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 GATA PF00320.27 EGB11794.1 - 0.072 12.7 0.3 0.072 12.7 0.3 1.7 2 0 0 2 2 2 0 GATA zinc finger Pribosyltran PF00156.27 EGB11795.1 - 8e-16 58.0 0.1 1.1e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGB11795.1 - 0.055 12.9 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase CtaG_Cox11 PF04442.14 EGB11796.1 - 2.4e-58 196.5 0.0 2.7e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 FTR1 PF03239.14 EGB11797.1 - 1e-36 126.7 9.4 1e-36 126.7 9.4 1.8 2 0 0 2 2 2 1 Iron permease FTR1 family Fea1 PF07692.11 EGB11797.1 - 7.4e-20 71.3 0.5 1.1e-18 67.4 0.5 2.2 1 1 0 1 1 1 1 Low iron-inducible periplasmic protein PrgI PF12666.7 EGB11797.1 - 6.5 7.5 9.8 5.7 7.7 0.2 3.7 3 0 0 3 3 3 0 PrgI family protein Syntaxin-6_N PF09177.11 EGB11798.1 - 8.8e-17 61.5 0.0 3.2e-14 53.3 0.0 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EGB11798.1 - 8.9e-06 25.6 1.0 8.9e-06 25.6 1.0 2.5 3 0 0 3 3 3 1 SNARE domain Tropomyosin PF00261.20 EGB11798.1 - 0.011 15.1 3.0 0.018 14.4 3.0 1.3 1 0 0 1 1 1 0 Tropomyosin DUF3584 PF12128.8 EGB11798.1 - 0.029 11.9 2.4 0.064 10.8 1.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Rab_bind PF16704.5 EGB11798.1 - 0.033 14.2 0.1 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Rab binding domain Spc7 PF08317.11 EGB11798.1 - 0.041 12.7 0.9 0.12 11.2 0.7 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 EGB11798.1 - 0.049 13.7 0.4 0.21 11.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EGB11798.1 - 0.44 10.6 4.2 0.14 12.2 0.4 2.0 3 0 0 3 3 3 0 Laminin Domain II Use1 PF09753.9 EGB11798.1 - 0.66 9.7 7.6 0.63 9.7 3.6 2.0 1 1 1 2 2 2 0 Membrane fusion protein Use1 VCBS PF13517.6 EGB11799.1 - 5.7e-55 183.8 138.4 8.4e-10 39.1 6.1 11.3 4 3 8 12 12 12 9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.6 EGB11799.1 - 1.3e-05 24.5 0.1 0.0021 17.5 0.0 11.7 12 0 0 12 12 12 5 EF hand EF-hand_6 PF13405.6 EGB11799.1 - 2.9e-05 23.6 0.0 0.0027 17.5 0.0 9.8 11 0 0 11 11 10 2 EF-hand domain EF-hand_1 PF00036.32 EGB11799.1 - 0.00027 20.3 0.0 0.017 14.6 0.0 11.2 12 0 0 12 12 12 2 EF hand EF-hand_7 PF13499.6 EGB11799.1 - 0.00031 21.1 0.0 0.00031 21.1 0.0 6.0 8 2 1 9 9 8 2 EF-hand domain pair HTH_31 PF13560.6 EGB11799.1 - 0.006 16.9 0.4 14 6.2 0.0 5.3 7 0 0 7 7 6 1 Helix-turn-helix domain FG-GAP PF01839.23 EGB11799.1 - 0.02 15.0 3.2 0.02 15.0 3.2 12.5 13 0 0 13 13 12 0 FG-GAP repeat Hydrolase_4 PF12146.8 EGB11799.1 - 0.031 13.5 0.3 9.6 5.4 0.0 2.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AbfS_sensor PF18225.1 EGB11799.1 - 0.084 12.8 0.0 26 4.8 0.0 3.8 4 0 0 4 4 4 0 Sensor histidine kinase (AbfS) sensor domain Dockerin_1 PF00404.18 EGB11799.1 - 0.19 12.0 61.2 1.1 9.5 3.4 11.1 11 1 1 12 12 12 0 Dockerin type I domain EF-hand_8 PF13833.6 EGB11799.1 - 0.8 9.6 0.0 0.8 9.6 0.0 6.3 9 0 0 9 9 8 0 EF-hand domain pair p450 PF00067.22 EGB11800.1 - 9.1e-70 235.7 0.0 4.2e-41 141.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Cytochrom_B562 PF07361.11 EGB11800.1 - 0.06 14.0 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b562 ABC_tran PF00005.27 EGB11801.1 - 7e-23 81.7 0.0 9.8e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGB11801.1 - 1.2e-07 31.4 0.9 1.7e-07 30.9 0.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 EGB11801.1 - 0.00015 21.7 0.3 0.21 11.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGB11801.1 - 0.006 16.5 0.1 0.0098 15.8 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGB11801.1 - 0.057 13.5 0.1 0.098 12.7 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EGB11801.1 - 0.11 12.1 1.4 0.16 11.5 0.5 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGB11801.1 - 0.12 12.6 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGB11801.1 - 0.25 10.8 0.1 2.1 7.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EGB11801.1 - 0.31 10.8 0.1 0.45 10.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain CAP_N PF01213.19 EGB11801.1 - 1.7 8.1 3.6 2.9 7.3 3.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DAGK_cat PF00781.24 EGB11802.1 - 1.6e-11 43.9 0.3 2.6e-11 43.2 0.3 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SSF PF00474.17 EGB11803.1 - 6.6e-06 25.2 15.1 1.2e-05 24.3 15.1 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Cupin_8 PF13621.6 EGB11803.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Cytochrom_B_C PF00032.17 EGB11803.1 - 0.18 12.1 1.0 0.48 10.7 0.1 2.2 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD zf-CW PF07496.15 EGB11804.1 - 3e-12 46.3 6.6 4.4e-12 45.8 6.6 1.3 1 0 0 1 1 1 1 CW-type Zinc Finger PRA-PH PF01503.17 EGB11805.1 - 1.3e-17 63.9 0.0 1.6e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Aminotran_5 PF00266.19 EGB11806.1 - 2.2e-134 448.1 0.0 2.5e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGB11806.1 - 2.7e-07 30.2 0.9 3.8e-06 26.4 2.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGB11806.1 - 3.3e-07 29.8 0.0 7.1e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGB11806.1 - 0.0056 15.3 0.0 0.02 13.5 0.0 1.6 1 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.22 EGB11808.1 - 2e-24 85.2 0.0 2.3e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB11808.1 - 0.0054 16.8 0.0 0.0078 16.3 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 EGB11808.1 - 0.0073 16.1 0.0 0.0093 15.8 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGB11808.1 - 0.04 13.5 0.0 0.054 13.1 0.0 1.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGB11808.1 - 0.19 12.0 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 EGB11809.1 - 2e-22 78.8 0.0 2.2e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 EGB11809.1 - 0.0061 16.7 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 EGB11809.1 - 0.037 13.9 0.0 0.048 13.5 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 EGB11809.1 - 0.044 13.9 0.0 0.065 13.4 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif PHM7_cyt PF14703.6 EGB11809.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1360 PF07098.11 EGB11810.1 - 0.17 11.8 2.2 0.57 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Ist1 PF03398.14 EGB11811.1 - 7.2e-56 188.6 1.3 8e-56 188.5 1.3 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ank_2 PF12796.7 EGB11812.1 - 2.1e-26 92.3 0.1 1.3e-12 48.1 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB11812.1 - 5e-22 78.0 0.7 3.2e-10 40.3 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB11812.1 - 5.1e-21 74.5 1.9 6.9e-05 23.1 0.3 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11812.1 - 4.2e-20 69.7 0.9 0.0018 18.6 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EGB11812.1 - 2.7e-17 62.3 5.3 0.00058 20.2 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat MFS_1 PF07690.16 EGB11814.1 - 5.4e-19 68.3 24.1 1.6e-15 56.9 15.3 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Mcm10 PF09332.11 EGB11814.1 - 0.16 11.3 9.3 0.23 10.8 9.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor PA26 PF04636.13 EGB11814.1 - 1.2 8.0 4.8 1.7 7.5 4.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF966 PF06136.13 EGB11814.1 - 1.5 8.5 7.0 2 8.0 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) KdgM PF06178.13 EGB11815.1 - 0.11 12.1 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Oligogalacturonate-specific porin protein (KdgM) DUF2059 PF09832.9 EGB11815.1 - 0.12 12.4 13.7 10 6.2 0.1 5.1 2 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2059) Proteasome PF00227.26 EGB11816.1 - 8.2e-39 133.1 0.4 5.5e-28 97.7 0.2 2.0 2 0 0 2 2 2 2 Proteasome subunit HAD_2 PF13419.6 EGB11817.1 - 5.7e-15 55.9 0.0 2.8e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB11817.1 - 5.1e-13 49.8 1.7 6.6e-10 39.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB11817.1 - 1.1e-09 38.2 0.2 2.3e-09 37.2 0.2 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGB11817.1 - 3.5e-07 30.8 0.7 1e-05 26.0 0.7 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGB11817.1 - 0.00055 20.0 0.0 0.00095 19.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGB11817.1 - 0.0024 17.5 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Acid_PPase PF12689.7 EGB11817.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 1 0 1 1 1 0 Acid Phosphatase tRNA-synt_2 PF00152.20 EGB11818.1 - 1e-46 159.5 0.0 1.2e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EGB11818.1 - 0.0033 16.9 0.2 0.41 10.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PAF-AH_p_II PF03403.13 EGB11819.1 - 8.1e-15 54.2 0.0 1.5e-14 53.3 0.0 1.5 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 EGB11819.1 - 0.084 12.5 0.2 0.084 12.5 0.2 1.7 2 1 0 2 2 2 0 Putative esterase AAA PF00004.29 EGB11820.1 - 1.5e-80 268.1 0.0 9.5e-46 155.5 0.0 2.5 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB11820.1 - 5.9e-22 77.2 8.5 4.6e-11 42.3 1.8 3.1 3 1 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 EGB11820.1 - 1.2e-11 45.3 3.0 0.00065 20.1 0.2 4.8 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 EGB11820.1 - 5.2e-11 42.5 0.0 1.6e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGB11820.1 - 1e-08 35.4 0.0 0.0064 16.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGB11820.1 - 2.9e-08 34.3 0.0 0.0082 16.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGB11820.1 - 3.1e-08 34.0 0.4 0.066 13.5 0.1 4.1 2 2 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 EGB11820.1 - 3.3e-08 33.6 0.0 0.0074 16.1 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 EGB11820.1 - 4.1e-08 33.5 0.0 0.008 16.3 0.0 2.8 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 EGB11820.1 - 2.4e-07 30.8 0.0 0.035 14.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 EGB11820.1 - 2.5e-07 30.8 0.4 0.042 13.8 0.0 3.5 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EGB11820.1 - 1e-06 29.2 0.3 0.043 14.2 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 EGB11820.1 - 4.1e-06 26.8 0.0 0.08 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGB11820.1 - 6.4e-06 26.5 0.0 0.038 14.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EGB11820.1 - 1.4e-05 25.4 0.2 0.25 11.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain Vps4_C PF09336.10 EGB11820.1 - 1.9e-05 24.6 0.0 0.018 15.0 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 EGB11820.1 - 2.3e-05 24.9 0.0 0.31 11.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter TsaE PF02367.17 EGB11820.1 - 2.7e-05 24.2 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGB11820.1 - 4.3e-05 23.0 0.1 0.037 13.4 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGB11820.1 - 0.00011 22.2 0.1 0.15 12.0 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 EGB11820.1 - 0.00017 21.4 0.1 0.021 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGB11820.1 - 0.00029 20.1 0.1 0.64 9.1 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TIP49 PF06068.13 EGB11820.1 - 0.00031 20.1 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 EGB11820.1 - 0.00041 20.0 2.1 0.6 9.7 0.1 3.3 2 1 1 4 4 4 2 AAA domain Zeta_toxin PF06414.12 EGB11820.1 - 0.00046 19.5 0.1 1 8.6 0.0 2.5 3 0 0 3 3 2 2 Zeta toxin AAA_7 PF12775.7 EGB11820.1 - 0.00053 19.5 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 EGB11820.1 - 0.00063 19.7 0.1 1.8 8.4 0.0 2.8 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EGB11820.1 - 0.001 18.9 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGB11820.1 - 0.0011 19.5 0.0 0.3 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 EGB11820.1 - 0.0013 18.6 0.0 2.3 8.0 0.0 3.2 2 1 0 2 2 2 1 Bacterial dnaA protein IstB_IS21 PF01695.17 EGB11820.1 - 0.0013 18.5 0.3 0.28 10.9 0.1 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 EGB11820.1 - 0.0015 17.8 0.0 0.19 10.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase PF06745.13 EGB11820.1 - 0.0017 17.8 0.1 0.17 11.2 0.0 2.8 3 1 0 3 3 3 1 KaiC AAA_24 PF13479.6 EGB11820.1 - 0.0024 17.6 0.6 3.6 7.2 0.1 3.0 4 0 0 4 4 3 1 AAA domain NTPase_1 PF03266.15 EGB11820.1 - 0.0024 17.8 0.1 1.9 8.3 0.0 2.8 3 0 0 3 3 2 1 NTPase AAA_29 PF13555.6 EGB11820.1 - 0.0027 17.4 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EGB11820.1 - 0.0041 17.5 0.2 2.2 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EGB11820.1 - 0.013 14.8 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 EGB11820.1 - 0.014 15.2 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EGB11820.1 - 0.027 13.6 0.0 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SKI PF01202.22 EGB11820.1 - 0.051 13.7 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 EGB11820.1 - 0.11 12.0 0.2 2.7 7.4 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.9 EGB11820.1 - 0.13 12.0 0.0 21 4.9 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EGB11820.1 - 0.14 11.7 0.2 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin2 PF13189.6 EGB11820.1 - 0.16 12.1 0.1 0.55 10.3 0.0 1.9 2 0 0 2 2 1 0 Cytidylate kinase-like family TniB PF05621.11 EGB11820.1 - 0.18 11.2 0.0 43 3.4 0.0 3.2 4 0 0 4 4 4 0 Bacterial TniB protein Sigma54_activat PF00158.26 EGB11820.1 - 0.2 11.4 0.0 2.5 7.8 0.0 2.4 3 0 0 3 3 2 0 Sigma-54 interaction domain DAP3 PF10236.9 EGB11820.1 - 0.23 10.6 0.0 8.7 5.4 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Vps53_N PF04100.12 EGB11822.1 - 5.9e-90 302.0 0.0 8.1e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal COG7 PF10191.9 EGB11822.1 - 2.2e-11 42.8 0.0 2.6e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Sec6 PF06046.13 EGB11822.1 - 0.015 13.7 0.0 1.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec6 Spc7 PF08317.11 EGB11822.1 - 0.049 12.5 0.4 0.076 11.9 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.9 EGB11822.1 - 0.062 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF4510 PF14971.6 EGB11822.1 - 0.066 13.6 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Bep_C_terminal PF17841.1 EGB11822.1 - 0.08 13.2 0.4 0.31 11.3 0.4 2.0 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) DUF2884 PF11101.8 EGB11822.1 - 0.086 12.3 0.6 0.36 10.3 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) COG2 PF06148.11 EGB11822.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CREPT PF16566.5 EGB11822.1 - 0.2 11.8 0.1 0.53 10.5 0.1 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Myosin_head PF00063.21 EGB11823.1 - 1.7e-200 667.7 0.0 2.4e-200 667.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB11823.1 - 0.011 16.2 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGB11823.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGB11823.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cupin_4 PF08007.12 EGB11824.1 - 2.6e-07 30.4 0.0 4.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EGB11824.1 - 4.4e-07 29.9 2.0 1.9e-06 27.8 2.0 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGB11824.1 - 0.026 14.9 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase Ribosomal_L36 PF00444.18 EGB11825.1 - 1.8e-19 69.7 11.8 2.3e-19 69.3 11.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.17 EGB11825.1 - 0.046 13.6 0.9 0.059 13.2 0.9 1.1 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Ion_trans PF00520.31 EGB11827.1 - 4.2e-06 26.2 0.6 6e-06 25.7 0.6 1.1 1 0 0 1 1 1 1 Ion transport protein Chloroa_b-bind PF00504.21 EGB11828.1 - 3.6e-33 115.4 0.1 4.4e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Glyco_hydro_20 PF00728.22 EGB11829.1 - 2.4e-38 132.4 0.0 7.8e-28 97.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGB11829.1 - 0.0047 17.6 0.0 0.0094 16.6 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like FeoC PF09012.10 EGB11829.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.8 3 0 0 3 3 3 0 FeoC like transcriptional regulator Tli4_C PF18426.1 EGB11829.1 - 0.19 12.0 0.1 0.41 10.9 0.1 1.5 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EGB11830.1 - 2.9e-07 31.3 0.0 6.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_9 PF13371.6 EGB11830.1 - 0.0074 16.4 8.4 0.0074 16.4 8.4 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11830.1 - 0.036 14.7 20.1 0.036 14.7 20.1 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF4810 PF16068.5 EGB11830.1 - 0.091 13.3 0.5 0.31 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) TPR_17 PF13431.6 EGB11830.1 - 0.39 11.2 3.7 72 4.1 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11830.1 - 0.89 9.7 4.9 8.4 6.7 0.7 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11830.1 - 2.6 8.6 18.4 1 9.9 4.7 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11830.1 - 5.5 7.4 11.4 3.1 8.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB11830.1 - 5.6 8.1 28.3 0.51 11.3 5.3 5.5 3 1 3 6 6 6 0 Tetratricopeptide repeat Ribosomal_S13 PF00416.22 EGB11831.1 - 2.3e-53 180.0 0.9 2.7e-53 179.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PHF12_MRG_bd PF16737.5 EGB11831.1 - 0.027 14.2 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain FbpA PF05833.11 EGB11831.1 - 0.038 12.7 0.1 0.078 11.7 0.0 1.3 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 EGB11831.1 - 0.05 14.0 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) NAD_binding_5 PF07994.12 EGB11831.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase PP28 PF10252.9 EGB11831.1 - 0.14 12.6 1.7 0.31 11.5 1.7 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Glycos_transf_2 PF00535.26 EGB11832.1 - 3.8e-20 72.4 0.0 5e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB11832.1 - 0.0004 20.4 0.0 0.00054 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GRIP PF01465.20 EGB11833.1 - 5.6e-14 51.8 0.0 3.8e-10 39.5 0.1 2.5 2 0 0 2 2 2 2 GRIP domain Tyrosinase PF00264.20 EGB11833.1 - 7.2e-13 49.3 0.2 3.6e-08 34.0 0.1 2.5 2 0 0 2 2 2 2 Common central domain of tyrosinase Pkinase PF00069.25 EGB11834.1 - 1.9e-43 148.8 0.0 2.1e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11834.1 - 8.4e-32 110.5 0.0 9.8e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB11834.1 - 9.6e-07 28.4 0.0 3.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGB11834.1 - 2.4e-05 24.4 4.7 0.0016 18.4 4.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB11834.1 - 2.7e-05 23.1 0.0 3.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGB11834.1 - 0.00053 19.0 0.0 0.00056 19.0 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGB11834.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EGB11834.1 - 0.021 15.0 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Actin PF00022.19 EGB11835.1 - 1.2e-90 304.0 0.0 6.6e-48 163.3 0.0 2.0 1 1 1 2 2 2 2 Actin DUF1826 PF08856.11 EGB11836.1 - 1.5e-13 51.2 1.2 2.7e-13 50.3 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1826) LRR_9 PF14580.6 EGB11836.1 - 0.00061 19.3 0.0 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EGB11836.1 - 0.0074 16.7 0.0 11 6.6 0.0 2.9 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) Med3 PF11593.8 EGB11836.1 - 9.6 5.3 5.8 15 4.6 5.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DOPA_dioxygen PF08883.11 EGB11837.1 - 4.9e-06 26.7 0.0 1.7e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family SUI1 PF01253.22 EGB11838.1 - 1.2e-24 86.7 1.8 1.6e-24 86.2 1.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Hydrophob_seed PF14547.6 EGB11838.1 - 0.0024 18.1 0.1 0.0035 17.5 0.1 1.3 1 0 0 1 1 1 1 Hydrophobic seed protein Zot PF05707.12 EGB11838.1 - 0.067 12.8 0.1 0.08 12.6 0.1 1.1 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TIG PF01833.24 EGB11839.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 IPT/TIG domain Methyltransf_16 PF10294.9 EGB11840.1 - 9e-11 41.8 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Lipase_GDSL_2 PF13472.6 EGB11840.1 - 9e-07 29.4 1.6 1.8e-06 28.5 0.4 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_25 PF13649.6 EGB11840.1 - 3e-05 24.6 0.2 9e-05 23.1 0.2 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGB11840.1 - 0.00015 21.3 0.6 0.00024 20.6 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGB11840.1 - 0.0016 18.0 0.2 0.0038 16.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGB11840.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB11840.1 - 0.012 16.2 0.1 0.03 15.0 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EGB11840.1 - 0.28 10.6 0.0 0.49 9.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB LRR_6 PF13516.6 EGB11841.1 - 2.8e-16 58.1 23.6 0.21 11.7 0.1 10.8 13 0 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.7 EGB11841.1 - 1.9e-11 44.0 0.0 0.0039 17.6 0.0 6.8 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB11841.1 - 1.7e-09 36.9 6.1 20 6.2 0.0 9.8 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.6 EGB11841.1 - 0.0036 17.0 0.1 1.3 8.8 0.0 4.7 5 1 0 5 5 5 1 Leucine rich repeat HHH_2 PF12826.7 EGB11841.1 - 0.015 15.4 0.0 0.95 9.6 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix motif DBC1 PF14443.6 EGB11841.1 - 1.2 9.1 3.2 71 3.4 0.0 3.8 3 1 1 4 4 4 0 DBC1 adh_short_C2 PF13561.6 EGB11843.1 - 2e-51 174.8 0.1 2.5e-51 174.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB11843.1 - 1.1e-36 126.2 0.0 1.4e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB11843.1 - 0.0013 18.7 0.4 0.014 15.3 0.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB11843.1 - 0.0022 17.5 0.1 0.034 13.6 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB11843.1 - 0.0089 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 EGB11843.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Abhydrolase_1 PF00561.20 EGB11845.1 - 1.8e-25 90.0 0.0 5.2e-24 85.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB11845.1 - 2e-10 40.3 0.0 3.1e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGB11845.1 - 4.4e-09 37.3 0.6 7.8e-09 36.5 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGB11845.1 - 0.0028 17.7 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein YqjK PF13997.6 EGB11845.1 - 0.26 11.6 0.1 0.26 11.6 0.1 2.2 3 0 0 3 3 3 0 YqjK-like protein AAA PF00004.29 EGB11846.1 - 5.9e-97 321.2 0.0 2e-47 160.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB11846.1 - 4.5e-27 93.6 6.7 7.1e-13 48.1 0.4 2.9 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EGB11846.1 - 4.7e-22 78.0 0.5 1.1e-21 76.8 0.5 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EGB11846.1 - 4e-14 52.7 0.0 1.3e-05 25.0 0.0 3.4 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 EGB11846.1 - 1.8e-13 50.0 0.0 4.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 EGB11846.1 - 7.1e-13 49.3 0.2 4.5e-05 23.9 0.0 4.0 3 2 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.14 EGB11846.1 - 1.5e-11 44.7 0.0 6.9e-06 26.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGB11846.1 - 2e-11 44.0 0.1 3.2e-06 27.2 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGB11846.1 - 2.2e-11 44.1 0.0 8.9e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGB11846.1 - 9.7e-10 38.9 0.5 0.022 15.0 0.1 4.4 3 2 1 4 4 3 2 AAA domain AAA_14 PF13173.6 EGB11846.1 - 2e-08 34.3 0.0 0.0015 18.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.13 EGB11846.1 - 5.1e-08 32.5 0.0 0.00077 18.8 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EGB11846.1 - 5.7e-07 29.9 0.0 0.018 15.4 0.0 3.3 4 0 0 4 4 2 2 RNA helicase AAA_18 PF13238.6 EGB11846.1 - 6.3e-07 30.0 0.0 0.038 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGB11846.1 - 1.2e-06 28.1 0.1 0.066 12.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EGB11846.1 - 9e-06 25.6 0.0 0.022 14.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EGB11846.1 - 1e-05 25.6 0.0 0.25 11.2 0.1 3.4 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea ATPase PF06745.13 EGB11846.1 - 1.3e-05 24.7 0.2 1.3 8.4 0.0 3.5 3 0 0 3 3 3 1 KaiC AAA_25 PF13481.6 EGB11846.1 - 1.5e-05 24.7 1.4 3.2 7.3 0.0 3.9 2 2 0 3 3 3 1 AAA domain AAA_17 PF13207.6 EGB11846.1 - 1.5e-05 25.4 0.0 0.09 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EGB11846.1 - 1.7e-05 24.6 0.0 0.29 10.9 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EGB11846.1 - 2e-05 24.2 0.0 0.14 11.7 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Bac_DnaA PF00308.18 EGB11846.1 - 3.9e-05 23.6 0.0 0.12 12.2 0.0 2.9 3 0 0 3 3 3 2 Bacterial dnaA protein ABC_tran PF00005.27 EGB11846.1 - 7.7e-05 23.2 0.0 0.4 11.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter Vps4_C PF09336.10 EGB11846.1 - 9e-05 22.4 0.3 0.0011 18.9 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 EGB11846.1 - 0.00012 21.8 0.1 0.14 11.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGB11846.1 - 0.00013 21.7 0.0 0.64 9.7 0.0 3.4 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 EGB11846.1 - 0.00014 21.9 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGB11846.1 - 0.00017 21.9 0.0 0.74 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EGB11846.1 - 0.0002 20.5 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 EGB11846.1 - 0.00022 21.4 0.0 0.19 11.8 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 EGB11846.1 - 0.00037 20.5 0.0 0.095 12.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 EGB11846.1 - 0.00044 20.2 0.0 2.7 7.9 0.0 3.4 3 1 1 4 4 4 2 NACHT domain NB-ARC PF00931.22 EGB11846.1 - 0.0005 19.3 0.0 0.93 8.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 EGB11846.1 - 0.00054 19.3 0.0 0.68 9.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Cytidylate_kin2 PF13189.6 EGB11846.1 - 0.00069 19.8 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family DUF815 PF05673.13 EGB11846.1 - 0.0012 18.0 0.0 0.38 9.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 EGB11846.1 - 0.0017 18.2 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGB11846.1 - 0.0021 18.0 0.0 0.46 10.4 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain PhoH PF02562.16 EGB11846.1 - 0.0033 16.9 0.1 3.6 7.0 0.0 2.8 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 EGB11846.1 - 0.0045 16.9 0.5 4.5 7.2 0.0 4.0 3 1 1 4 4 4 0 NTPase UFD1 PF03152.14 EGB11846.1 - 0.0048 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF2075 PF09848.9 EGB11846.1 - 0.005 16.1 0.0 0.89 8.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGB11846.1 - 0.011 16.1 1.4 8.6 6.7 0.1 3.9 4 1 0 5 5 3 0 AAA domain AAA_30 PF13604.6 EGB11846.1 - 0.012 15.4 0.1 7.2 6.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGB11846.1 - 0.014 15.2 0.1 6.2 6.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain KAP_NTPase PF07693.14 EGB11846.1 - 0.029 13.6 0.0 1.2 8.3 0.0 3.0 2 1 1 3 3 3 0 KAP family P-loop domain Cytidylate_kin PF02224.18 EGB11846.1 - 0.047 13.4 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 EGB11846.1 - 0.049 13.8 0.9 13 5.8 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase Zot PF05707.12 EGB11846.1 - 0.058 13.0 0.0 1.7 8.2 0.0 2.8 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_29 PF13555.6 EGB11846.1 - 0.1 12.4 0.0 7.1 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Chloroa_b-bind PF00504.21 EGB11848.1 - 6.6e-30 104.8 0.8 8.2e-30 104.5 0.8 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein GST_N_2 PF13409.6 EGB11849.1 - 8.1e-13 48.5 0.1 1.3e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB11849.1 - 1.7e-11 44.3 0.0 6.8e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB11849.1 - 9.5e-08 32.0 1.6 2.4e-07 30.7 1.6 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB11849.1 - 2.4e-06 27.8 0.0 5.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EGB11849.1 - 6.9e-05 23.0 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 EGB11849.1 - 0.0017 18.9 0.1 0.0054 17.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB11849.1 - 0.016 15.4 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FMO-like PF00743.19 EGB11850.1 - 9.8e-56 189.3 0.1 3.8e-42 144.4 0.0 3.2 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGB11850.1 - 8.9e-11 41.5 2.1 1.6e-07 30.9 0.2 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGB11850.1 - 2.3e-10 40.2 2.0 8.4e-07 28.5 0.0 3.2 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB11850.1 - 8.1e-10 38.3 0.2 8.9e-07 28.4 0.0 3.4 2 2 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) SET PF00856.28 EGB11850.1 - 5e-07 30.2 0.0 5e-07 30.2 0.0 2.9 2 1 0 2 2 1 1 SET domain NAD_binding_8 PF13450.6 EGB11850.1 - 6.2e-05 23.2 3.7 0.00013 22.1 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGB11850.1 - 0.00021 21.3 1.3 0.087 12.8 0.0 4.4 5 0 0 5 5 5 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EGB11850.1 - 0.0017 18.8 1.1 0.24 11.9 0.0 3.2 3 0 0 3 3 3 1 Putative NAD(P)-binding Pyr_redox PF00070.27 EGB11850.1 - 0.0026 18.3 4.8 0.79 10.3 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGB11850.1 - 0.0062 16.6 0.2 0.048 13.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EGB11850.1 - 0.23 11.1 0.5 9.3 5.9 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_24 PF13578.6 EGB11850.1 - 0.77 10.8 5.7 0.29 12.2 0.9 2.8 2 0 0 2 2 2 0 Methyltransferase domain TMP_2 PF06791.13 EGB11850.1 - 1.3 8.7 11.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Prophage tail length tape measure protein LMBR1 PF04791.16 EGB11850.1 - 2 7.2 6.4 2.9 6.7 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RRM_occluded PF16842.5 EGB11851.1 - 0.073 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_1 PF00076.22 EGB11851.1 - 0.081 12.8 0.0 0.69 9.8 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PT PF04886.12 EGB11852.1 - 9.4e-14 50.7 169.8 0.0012 18.3 20.4 10.4 2 1 4 6 6 6 4 PT repeat ABC_tran PF00005.27 EGB11853.1 - 2.9e-42 144.4 0.0 2.7e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGB11853.1 - 2.9e-18 66.5 6.4 1.4e-11 44.5 3.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region Ank_4 PF13637.6 EGB11853.1 - 1.1e-12 48.2 0.1 2.4e-07 31.1 0.0 4.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB11853.1 - 1.7e-09 38.1 7.4 2e-08 34.7 0.0 4.1 4 0 0 4 4 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB11853.1 - 6e-09 36.0 14.0 3.8e-05 23.9 0.0 5.7 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11853.1 - 2.7e-07 30.4 5.3 4.7e-05 23.5 0.0 5.3 5 0 0 5 5 3 1 Ankyrin repeat SMC_N PF02463.19 EGB11853.1 - 2.1e-05 24.1 0.8 0.023 14.1 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB11853.1 - 6.2e-05 22.7 0.7 0.34 10.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGB11853.1 - 6.8e-05 22.9 0.7 0.049 13.7 0.2 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Ank PF00023.30 EGB11853.1 - 0.00011 22.5 8.0 0.0011 19.3 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat AAA_22 PF13401.6 EGB11853.1 - 0.00067 19.9 0.4 1.7 8.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGB11853.1 - 0.0015 18.9 11.3 0.0057 17.1 0.6 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGB11853.1 - 0.0017 18.2 0.2 5.5 6.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGB11853.1 - 0.0071 16.1 5.1 0.15 11.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGB11853.1 - 0.022 14.8 0.7 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 EGB11853.1 - 0.027 14.4 0.6 5.2 6.9 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 EGB11853.1 - 0.032 14.7 0.0 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGB11853.1 - 0.054 12.5 0.0 4.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 EGB11853.1 - 0.06 13.5 0.2 6.6 6.9 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGB11853.1 - 0.097 13.2 0.0 17 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EGB11853.1 - 0.13 11.2 1.6 6 5.8 0.2 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EGB11853.1 - 0.16 11.2 1.0 5.7 6.2 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EGB11853.1 - 0.22 11.1 1.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EGB11853.1 - 4.2 7.4 5.0 1.1 9.3 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Sel1 PF08238.12 EGB11854.1 - 6.8e-29 99.7 14.2 1.2e-07 32.2 1.1 4.3 4 0 0 4 4 4 4 Sel1 repeat TPR_7 PF13176.6 EGB11854.1 - 0.00097 19.0 0.8 0.037 14.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11854.1 - 0.041 14.2 0.6 0.041 14.2 0.6 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB11854.1 - 0.053 13.4 0.2 0.77 9.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGB11854.1 - 0.071 13.3 1.4 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11854.1 - 0.075 13.2 4.5 0.4 10.9 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11854.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat U-box PF04564.15 EGB11855.1 - 1.2e-19 70.2 0.0 1.4e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB11855.1 - 3.3e-06 26.8 0.0 4.1e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EGB11855.1 - 0.00016 21.8 0.1 0.00032 20.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGB11855.1 - 0.016 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 RING-type zinc-finger EPSP_synthase PF00275.20 EGB11856.1 - 7.7e-126 420.2 0.1 8.8e-126 419.9 0.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Na_H_antiport_3 PF07399.11 EGB11856.1 - 0.94 8.3 3.6 1.2 8.0 1.1 1.9 1 1 1 2 2 2 0 Putative Na+/H+ antiporter Peptidase_S26 PF10502.9 EGB11857.1 - 5.7e-10 39.1 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EGB11857.1 - 4.3e-08 33.0 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase S24-like Glyco_hydro_99 PF16317.5 EGB11858.1 - 0.0061 15.7 0.0 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 99 E1-E2_ATPase PF00122.20 EGB11859.1 - 3.4e-46 157.0 1.2 3.4e-46 157.0 1.2 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGB11859.1 - 3.7e-36 124.6 0.0 8.7e-36 123.3 0.0 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGB11859.1 - 4.9e-21 76.0 5.5 1.9e-20 74.1 5.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGB11859.1 - 9.8e-16 57.2 0.0 1.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGB11859.1 - 3.6e-11 43.0 0.0 8.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGB11859.1 - 0.00055 19.8 0.5 0.00084 19.1 0.5 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PALP PF00291.25 EGB11860.1 - 1.1e-27 97.3 2.4 1.2e-27 97.2 2.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UPRTase PF14681.6 EGB11860.1 - 0.06 12.8 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase WD40 PF00400.32 EGB11861.1 - 2.5e-64 211.7 15.3 1.5e-10 41.5 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11861.1 - 2.7e-18 66.0 0.4 0.037 14.3 0.0 5.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB11861.1 - 5.1e-15 55.3 9.4 0.013 14.4 0.1 6.8 1 1 6 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGB11861.1 - 1.9e-08 33.4 7.6 0.047 12.3 0.0 5.7 5 2 2 7 7 7 3 Nucleoporin Nup120/160 PD40 PF07676.12 EGB11861.1 - 8.7e-06 25.5 0.3 5.8 7.0 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGB11861.1 - 5.3e-05 23.2 0.0 1.1 9.1 0.0 3.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A CelD_N PF02927.14 EGB11861.1 - 8e-05 23.4 0.0 0.25 12.2 0.0 4.7 4 1 2 6 6 6 1 Cellulase N-terminal ig-like domain DPPIV_N PF00930.21 EGB11861.1 - 0.0011 17.8 0.0 17 4.0 0.0 4.0 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TGBp3 PF02495.17 EGB11861.1 - 0.024 14.3 0.1 16 5.2 0.1 3.4 3 0 0 3 3 3 0 Triple gene block 3 DUF3261 PF11659.8 EGB11861.1 - 0.16 11.8 0.0 2.5 7.9 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3261) WD40_like PF17005.5 EGB11861.1 - 0.21 10.9 0.0 17 4.6 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain BAT PF15915.5 EGB11861.1 - 0.4 10.6 3.7 8.6 6.2 0.1 3.1 2 1 1 3 3 3 0 GAF and HTH_10 associated domain Proteasome_A_N PF10584.9 EGB11861.1 - 0.6 9.9 3.1 37 4.1 0.0 3.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Myb_DNA-binding PF00249.31 EGB11862.1 - 2.9e-24 85.0 8.0 1.4e-14 54.0 0.4 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB11862.1 - 2e-15 56.8 1.9 1.2e-09 38.2 0.3 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB11862.1 - 8.4e-07 28.8 0.1 3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EGB11862.1 - 0.018 15.0 0.0 0.16 12.0 0.0 1.9 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_2 PF08914.11 EGB11862.1 - 0.023 14.8 0.1 0.87 9.8 0.1 2.6 2 1 0 2 2 2 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EGB11862.1 - 0.11 12.7 0.4 5.7 7.2 0.0 2.2 1 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Pectate_lyase_3 PF12708.7 EGB11863.1 - 0.0099 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Pectate lyase superfamily protein Ribonuc_L-PSP PF01042.21 EGB11864.1 - 6.9e-26 90.6 0.0 8.7e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP PQQ_3 PF13570.6 EGB11864.1 - 0.067 13.7 0.8 0.27 11.8 0.6 2.2 1 1 0 1 1 1 0 PQQ-like domain Methyltransf_21 PF05050.12 EGB11865.1 - 4.1e-13 49.7 0.0 7.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain Sulfotransfer_3 PF13469.6 EGB11865.1 - 0.0015 18.9 0.1 0.032 14.6 0.0 2.4 1 1 1 2 2 2 1 Sulfotransferase family NHL PF01436.21 EGB11865.1 - 0.021 14.8 3.6 2.2 8.5 0.0 5.0 4 0 0 4 4 4 0 NHL repeat Glyco_transf_90 PF05686.12 EGB11865.1 - 0.27 10.1 0.0 7.2 5.4 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 90 TPR_17 PF13431.6 EGB11865.1 - 0.48 10.9 5.2 4.5 7.9 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB11865.1 - 0.51 10.6 23.7 1 9.6 2.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Transcrip_reg PF01709.20 EGB11866.1 - 4.2e-65 219.5 0.0 4.8e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF4530 PF15039.6 EGB11866.1 - 0.069 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Hydrolase_4 PF12146.8 EGB11867.1 - 3.5e-13 49.4 0.2 1e-12 47.9 0.2 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGB11867.1 - 7.8e-10 38.8 0.1 2e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGB11867.1 - 6.3e-07 29.3 0.1 1.4e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB11867.1 - 2.5e-06 27.1 0.1 0.0053 16.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 EGB11867.1 - 0.0046 16.6 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 EGB11867.1 - 0.0055 16.3 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family FYVE PF01363.21 EGB11867.1 - 0.0078 16.3 1.8 0.021 15.0 1.8 1.8 1 0 0 1 1 1 1 FYVE zinc finger FSH1 PF03959.13 EGB11867.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) IBR PF01485.21 EGB11867.1 - 1 9.7 3.4 1 9.7 1.3 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2HC5 PF06221.13 EGB11867.1 - 1.5 8.8 8.7 1.1 9.3 2.1 2.9 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type Glyco_transf_92 PF01697.27 EGB11869.1 - 6.3e-12 45.7 0.0 2.3e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EGB11869.1 - 9e-07 29.3 0.0 3.5e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 CENP-F_leu_zip PF10473.9 EGB11869.1 - 0.45 10.5 1.6 6.5 6.8 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GBP PF02263.19 EGB11870.1 - 9.6e-17 61.1 0.0 1.6e-15 57.1 0.0 2.1 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Hydrolase_4 PF12146.8 EGB11870.1 - 5.1e-11 42.3 0.0 2.2e-09 37.0 0.0 2.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB11870.1 - 9.6e-07 28.7 2.4 1.5e-06 28.1 0.1 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold GREB1 PF15782.5 EGB11870.1 - 4.1 4.4 12.3 5.4 4.0 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TPK_catalytic PF04263.16 EGB11871.1 - 1.1e-28 99.7 0.0 1.6e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EGB11871.1 - 1.7e-16 59.7 0.0 2.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain WD40 PF00400.32 EGB11872.1 - 6.1e-22 77.5 13.9 9.3e-08 32.6 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB11872.1 - 7.3e-18 64.7 2.8 6.4e-05 23.2 0.0 5.3 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGB11872.1 - 4.7e-06 25.4 0.1 0.0024 16.5 0.0 2.9 2 1 1 3 3 3 2 Cytochrome D1 heme domain IKI3 PF04762.12 EGB11872.1 - 0.047 11.7 0.2 0.23 9.4 0.0 2.0 2 1 0 2 2 2 0 IKI3 family NAD_binding_8 PF13450.6 EGB11873.1 - 6.8e-11 42.2 0.1 1.9e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGB11873.1 - 2.2e-10 40.2 3.5 6.7e-08 32.0 0.7 2.3 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 EGB11873.1 - 2.4e-08 33.7 1.5 2.7e-07 30.2 0.1 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGB11873.1 - 5e-08 32.9 0.2 1.2e-05 25.0 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGB11873.1 - 3.5e-05 23.2 0.2 0.00016 21.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB11873.1 - 5.7e-05 22.0 0.5 0.015 14.0 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 EGB11873.1 - 9.1e-05 21.8 0.5 0.00015 21.1 0.5 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EGB11873.1 - 0.00033 20.0 0.8 0.00054 19.3 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGB11873.1 - 0.0031 16.9 0.9 0.0031 16.9 0.9 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB11873.1 - 0.013 16.0 0.5 0.013 16.0 0.5 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EGB11873.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 EGB11873.1 - 1 8.5 3.0 4 6.6 1.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB11873.1 - 1.2 8.1 5.3 0.69 8.9 1.5 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A AOX PF01786.17 EGB11874.1 - 5.3e-63 212.5 0.4 1e-62 211.5 0.4 1.5 1 0 0 1 1 1 1 Alternative oxidase PALP PF00291.25 EGB11874.1 - 1.4e-53 182.2 12.4 3e-53 181.2 12.4 1.6 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SNF2_N PF00176.23 EGB11874.1 - 4e-17 62.0 0.0 2.2e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 EGB11874.1 - 1.8e-13 50.6 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase PP-binding PF00550.25 EGB11874.1 - 0.00025 21.4 0.1 0.00066 20.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Helicase_C PF00271.31 EGB11874.1 - 0.004 17.5 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGB11874.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PDEase_I PF00233.19 EGB11875.1 - 7.2e-73 245.2 0.2 1.1e-72 244.6 0.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EGB11875.1 - 0.25 11.6 2.9 0.21 11.8 0.8 2.0 2 1 0 2 2 2 0 HD domain HEAT PF02985.22 EGB11876.1 - 2.9e-25 86.2 48.9 0.0016 18.5 0.4 12.8 13 0 0 13 13 13 9 HEAT repeat HEAT_2 PF13646.6 EGB11876.1 - 2.2e-17 63.2 55.9 2.7e-07 30.9 3.1 7.3 2 1 6 8 8 8 7 HEAT repeats Arm PF00514.23 EGB11876.1 - 1.6e-06 28.0 6.0 0.73 10.0 0.0 6.1 5 1 1 6 6 6 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGB11876.1 - 1.4e-05 25.2 1.5 2.2 8.3 0.0 4.7 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGB11876.1 - 1.8e-05 25.1 49.0 0.00038 20.9 3.5 9.4 7 3 3 10 10 10 3 HEAT-like repeat KH_8 PF17903.1 EGB11877.1 - 6.2e-29 99.9 0.0 1.1e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain Aldedh PF00171.22 EGB11878.1 - 2.7e-107 359.2 0.1 3e-107 359.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.25 EGB11879.1 - 3.6e-63 213.3 0.0 5e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB11879.1 - 2.4e-49 166.7 0.0 3.5e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain WW PF00397.26 EGB11880.1 - 3.1e-05 24.0 1.8 5.2e-05 23.2 1.8 1.4 1 0 0 1 1 1 1 WW domain ADH_zinc_N PF00107.26 EGB11880.1 - 0.00026 20.9 0.0 0.00071 19.6 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 EGB11880.1 - 0.00086 18.6 2.2 0.0011 18.2 1.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGB11880.1 - 0.0017 17.7 1.2 0.0026 17.1 1.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGB11880.1 - 0.0041 17.0 0.6 0.0056 16.6 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EGB11880.1 - 0.016 14.9 0.2 0.031 13.9 0.1 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EGB11880.1 - 0.02 15.5 1.2 0.063 13.8 1.2 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB11880.1 - 0.025 14.8 1.4 0.15 12.3 0.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 EGB11880.1 - 0.045 13.3 0.5 0.086 12.4 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 EGB11880.1 - 0.066 12.8 8.8 0.22 11.1 8.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF1275 PF06912.11 EGB11881.1 - 4.2e-24 85.5 17.0 5.4e-24 85.2 17.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Myb_DNA-binding PF00249.31 EGB11882.1 - 3.1e-22 78.5 1.2 2.5e-16 59.6 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB11882.1 - 4.5e-18 65.2 0.0 3.5e-09 36.8 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGB11882.1 - 0.078 12.9 0.0 0.095 12.6 0.0 1.1 1 0 0 1 1 1 0 Myb DNA-binding like Rap1_C PF11626.8 EGB11882.1 - 0.082 13.0 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain IBR PF01485.21 EGB11883.1 - 2.2e-07 31.0 11.0 2.1e-06 27.9 5.0 3.8 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain UIM PF02809.20 EGB11883.1 - 3.1e-07 29.9 15.7 0.037 13.9 1.6 3.7 3 0 0 3 3 3 3 Ubiquitin interaction motif WW PF00397.26 EGB11883.1 - 1.1e-06 28.7 4.6 2.4e-06 27.5 4.6 1.6 1 0 0 1 1 1 1 WW domain CSD PF00313.22 EGB11883.1 - 0.00017 21.3 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-RING_UBOX PF13445.6 EGB11883.1 - 0.0004 20.3 0.2 0.0004 20.3 0.2 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGB11883.1 - 0.00082 19.7 0.6 0.00082 19.7 0.6 4.0 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 EGB11883.1 - 0.00092 19.0 0.1 0.00092 19.0 0.1 3.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB11883.1 - 0.0072 16.2 0.3 0.0072 16.2 0.3 3.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGB11883.1 - 0.28 11.0 9.3 0.018 14.8 2.6 2.5 2 1 0 2 2 2 0 RING-like zinc finger zinc_ribbon_15 PF17032.5 EGB11883.1 - 1.8 9.3 8.3 0.32 11.8 3.6 2.3 2 0 0 2 2 2 0 zinc-ribbon family CTP_synth_N PF06418.14 EGB11884.1 - 2.3e-123 410.7 0.0 2.8e-123 410.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGB11884.1 - 1e-54 185.2 0.0 1.5e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGB11884.1 - 0.0033 17.2 0.1 0.026 14.3 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EGB11884.1 - 0.06 13.1 0.1 0.31 10.8 0.1 2.2 3 0 0 3 3 3 0 DJ-1/PfpI family CbiA PF01656.23 EGB11884.1 - 0.085 12.9 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EGB11884.1 - 0.21 10.5 0.5 0.36 9.8 0.5 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ADH_zinc_N PF00107.26 EGB11885.1 - 7.9e-09 35.6 0.5 7.9e-09 35.6 0.5 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGB11885.1 - 2.7e-06 27.2 0.4 4.2e-05 23.4 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGB11885.1 - 0.00063 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase SseB PF07179.12 EGB11885.1 - 0.016 15.4 0.4 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 SseB protein N-terminal domain PhyH PF05721.13 EGB11886.1 - 3.3e-07 30.8 0.3 5.4e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EGB11886.1 - 2.2e-06 26.7 0.0 0.031 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) TauD PF02668.16 EGB11886.1 - 0.0064 16.3 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_1 PF00036.32 EGB11888.1 - 6.6e-81 260.0 33.6 0.0003 20.1 0.0 19.1 19 0 0 19 19 19 18 EF hand EF-hand_6 PF13405.6 EGB11888.1 - 1.4e-68 221.0 21.6 0.0079 16.1 0.1 19.6 19 0 0 19 19 19 17 EF-hand domain EF-hand_7 PF13499.6 EGB11888.1 - 9.7e-67 221.4 19.6 6.9e-07 29.6 0.1 10.8 10 1 0 10 10 10 9 EF-hand domain pair EF-hand_5 PF13202.6 EGB11888.1 - 3e-43 143.4 31.0 0.021 14.3 0.1 19.0 20 0 0 20 20 20 14 EF hand EF-hand_8 PF13833.6 EGB11888.1 - 4.4e-34 116.1 47.3 0.26 11.2 0.1 18.2 18 0 0 18 18 18 14 EF-hand domain pair DUF600 PF04634.12 EGB11888.1 - 0.0001 22.4 0.0 69 3.5 0.0 6.0 7 0 0 7 7 7 0 Protein of unknown function, DUF600 Nucleoporin2 PF04096.14 EGB11888.1 - 0.00021 21.4 0.9 64 3.6 0.0 6.3 6 0 0 6 6 6 0 Nucleoporin autopeptidase EF-hand_13 PF17958.1 EGB11888.1 - 0.0024 17.6 0.0 2e+02 1.9 0.0 7.5 10 0 0 10 10 10 0 EF-hand domain Flexi_CP_N PF08358.10 EGB11888.1 - 0.0088 16.0 0.7 6.7 6.8 0.0 4.7 6 0 0 6 6 6 1 Carlavirus coat Glyco_hydro_79C PF16862.5 EGB11888.1 - 1.6 9.6 5.7 3.3e+02 2.2 0.0 5.4 7 0 0 7 7 7 0 Glycosyl hydrolase family 79 C-terminal beta domain Mito_carr PF00153.27 EGB11889.1 - 3.8e-40 135.7 0.0 2.6e-12 46.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Raffinose_syn PF05691.12 EGB11890.1 - 1.5e-119 399.9 0.0 3.8e-68 230.0 0.0 2.0 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 EF-hand_6 PF13405.6 EGB11892.1 - 2.1e-11 42.8 1.5 0.0093 15.8 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EGB11892.1 - 1.6e-08 34.3 4.3 8e-05 22.4 0.6 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EGB11892.1 - 1.6e-08 34.8 3.4 0.0003 21.2 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB11892.1 - 9.5e-08 31.1 7.4 0.01 15.3 0.3 3.7 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EGB11892.1 - 7.2e-07 28.4 2.0 0.04 13.4 0.1 3.5 3 0 0 3 3 3 3 EF hand Exo_endo_phos PF03372.23 EGB11893.1 - 4.3e-07 29.7 0.6 8.5e-07 28.7 0.6 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PBP1_TM PF14812.6 EGB11894.1 - 0.73 10.2 4.5 0.28 11.6 1.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_10 PF13460.6 EGB11895.1 - 1.4e-39 135.9 8.2 9.2e-38 130.0 8.2 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGB11895.1 - 1.1e-11 44.8 0.6 1.7e-11 44.1 0.6 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGB11895.1 - 5e-07 29.4 0.1 8.9e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB11895.1 - 5.7e-06 25.5 0.2 8.2e-06 25.0 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EGB11895.1 - 0.0032 17.6 2.3 0.0056 16.8 1.8 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EGB11895.1 - 0.031 13.4 0.3 3.7 6.6 0.0 2.8 2 1 0 2 2 2 0 Male sterility protein PAC2 PF09754.9 EGB11895.1 - 0.041 13.9 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 PAC2 family Semialdhyde_dh PF01118.24 EGB11895.1 - 0.06 13.8 0.6 0.15 12.5 0.3 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EGB11895.1 - 0.11 11.6 1.9 0.4 9.8 1.9 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_6 PF12774.7 EGB11896.1 - 2.7e-143 476.8 0.0 8.1e-143 475.3 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGB11896.1 - 1.1e-129 433.1 5.6 1.1e-129 433.1 5.6 3.2 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGB11896.1 - 4e-103 344.8 0.0 1.2e-102 343.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGB11896.1 - 2.5e-100 335.1 0.0 6.1e-100 333.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGB11896.1 - 4e-87 290.9 2.3 4e-87 290.9 2.3 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGB11896.1 - 3.1e-81 271.2 0.6 2.3e-77 258.6 0.0 3.7 4 0 0 4 4 3 1 P-loop containing dynein motor region Aminotran_1_2 PF00155.21 EGB11896.1 - 4.7e-59 200.4 0.0 8.8e-59 199.5 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_lid_11 PF18198.1 EGB11896.1 - 1.2e-57 194.3 0.0 2.8e-57 193.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGB11896.1 - 7.4e-51 173.2 12.5 1.6e-50 172.0 12.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGB11896.1 - 6.8e-46 155.2 0.0 1.5e-43 147.7 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGB11896.1 - 1.7e-24 86.4 0.0 1.2e-23 83.6 0.0 2.6 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGB11896.1 - 1.9e-18 66.5 0.0 8.6e-18 64.4 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB11896.1 - 2.1e-13 50.4 0.0 0.005 16.9 0.0 5.3 5 1 0 5 5 3 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EGB11896.1 - 0.00037 20.9 0.1 0.83 10.1 0.0 4.9 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGB11896.1 - 0.00088 18.9 0.4 0.4 10.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 EGB11896.1 - 0.0015 18.3 0.4 2.1 8.0 0.1 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain DHR10 PF18595.1 EGB11896.1 - 0.0023 18.0 9.0 0.0023 18.0 9.0 6.7 8 1 1 9 9 4 1 Designed helical repeat protein 10 domain AAA_22 PF13401.6 EGB11896.1 - 0.0059 16.9 0.0 26 5.1 0.0 4.9 5 0 0 5 5 4 0 AAA domain Lipase_GDSL_2 PF13472.6 EGB11896.1 - 0.0076 16.7 2.2 0.0097 16.3 0.2 2.3 2 0 0 2 2 1 1 GDSL-like Lipase/Acylhydrolase family AAA_18 PF13238.6 EGB11896.1 - 0.029 14.9 0.0 2.4 8.7 0.0 4.3 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 EGB11896.1 - 0.065 12.3 0.1 12 4.9 0.0 3.7 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA_30 PF13604.6 EGB11896.1 - 0.065 12.9 0.1 5.8 6.6 0.1 3.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB11896.1 - 0.07 12.5 0.6 10 5.4 0.1 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Prominin PF05478.11 EGB11896.1 - 0.077 10.9 1.2 0.22 9.5 1.2 1.7 1 0 0 1 1 1 0 Prominin RNA_helicase PF00910.22 EGB11896.1 - 0.095 13.1 0.2 18 5.8 0.0 3.6 3 0 0 3 3 3 0 RNA helicase Sec8_exocyst PF04048.14 EGB11896.1 - 0.1 12.5 6.9 3.9 7.4 0.1 3.7 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain MscS_porin PF12795.7 EGB11896.1 - 0.15 11.6 15.4 0.0035 16.9 2.9 3.3 3 0 0 3 3 2 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.12 EGB11896.1 - 0.67 10.0 3.0 0.98 9.5 0.0 2.9 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 EGB11896.1 - 1.1 9.3 11.0 0.39 10.7 4.4 3.5 3 0 0 3 3 2 0 Laminin Domain II RecG_N PF17190.4 EGB11896.1 - 2 9.2 0.0 2 9.2 0.0 4.7 4 0 0 4 4 3 0 RecG N-terminal helical domain THOC7 PF05615.13 EGB11897.1 - 0.21 11.9 2.3 0.36 11.1 2.3 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Sel1 PF08238.12 EGB11898.1 - 4.7e-19 68.4 22.7 3.8e-07 30.6 2.8 4.4 4 0 0 4 4 4 3 Sel1 repeat HNF_C PF09354.10 EGB11899.1 - 0.2 12.7 0.0 0.62 11.1 0.0 1.8 1 0 0 1 1 1 0 HNF3 C-terminal domain cNMP_binding PF00027.29 EGB11900.1 - 1.1e-16 60.6 0.1 1.2e-16 60.5 0.1 1.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Kinesin PF00225.23 EGB11901.1 - 3e-102 342.0 0.0 4.8e-102 341.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB11901.1 - 3.5e-20 72.5 0.1 1.6e-19 70.3 0.0 2.1 3 0 0 3 3 3 1 Microtubule binding Spc24 PF08286.11 EGB11901.1 - 0.17 12.1 4.4 0.38 11.0 4.4 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4239 PF14023.6 EGB11901.1 - 0.24 11.1 1.0 0.37 10.5 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) MFS_1 PF07690.16 EGB11902.1 - 4.4e-17 62.0 38.4 1e-16 60.9 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB11902.1 - 1.6e-06 27.3 12.6 0.0041 16.1 0.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Glycos_transf_2 PF00535.26 EGB11903.1 - 1.6e-06 28.0 0.0 9.1e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGB11903.1 - 2.3e-05 24.4 0.0 3.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGB11903.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 21 HhH-GPD PF00730.25 EGB11904.1 - 1.1e-14 54.8 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGB11904.1 - 9.9e-08 31.5 0.0 3.1e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EGB11904.1 - 0.0064 17.1 0.0 0.066 13.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain Imm2 PF14426.6 EGB11904.1 - 0.14 12.3 0.1 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Immunity protein Imm2 p450 PF00067.22 EGB11905.1 - 7.4e-58 196.4 0.0 1.2e-57 195.7 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGB11906.1 - 8.3e-22 77.8 0.0 1e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11906.1 - 3.4e-11 42.9 0.0 4.8e-11 42.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB11906.1 - 2.4e-05 23.3 0.0 3.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB11906.1 - 0.00014 21.9 0.0 0.0024 17.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family JAB PF01398.21 EGB11907.1 - 5.2e-26 90.9 0.0 5.7e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGB11907.1 - 2.4e-07 30.6 0.1 2.7e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EGB11907.1 - 7e-05 23.0 0.0 8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) SelR PF01641.18 EGB11908.1 - 4.1e-29 101.1 0.2 4.5e-29 101.0 0.2 1.0 1 0 0 1 1 1 1 SelR domain TF_Zn_Ribbon PF08271.12 EGB11908.1 - 0.0076 15.7 1.1 1.4 8.5 0.2 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 EGB11908.1 - 0.0082 15.9 0.3 0.21 11.3 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Trm112p PF03966.16 EGB11908.1 - 0.011 16.3 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Trm112p-like protein DZR PF12773.7 EGB11908.1 - 0.012 15.6 0.7 0.055 13.5 0.3 2.1 1 1 1 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.14 EGB11908.1 - 0.015 15.5 0.1 0.022 15.0 0.1 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nudix_N_2 PF14803.6 EGB11908.1 - 0.045 13.7 1.5 7 6.7 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal GFA PF04828.14 EGB11908.1 - 0.05 14.0 0.5 4 7.8 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.6 EGB11908.1 - 0.075 13.2 0.6 1 9.5 0.1 2.3 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.6 EGB11908.1 - 0.086 12.6 3.0 6.2 6.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EGB11908.1 - 0.47 9.9 4.9 5.9 6.5 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 EGB11908.1 - 1.2 8.8 5.7 1.1 9.0 0.1 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain PMSR PF01625.21 EGB11909.1 - 4.4e-60 202.3 1.5 5.3e-60 202.0 1.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Peptidase_M18 PF02127.15 EGB11910.1 - 1.6e-138 462.1 0.0 1.9e-138 461.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGB11910.1 - 2.1e-06 27.0 0.1 0.0015 17.6 0.1 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Sulfatase PF00884.23 EGB11911.1 - 9.9e-49 166.4 0.0 1.4e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB11911.1 - 3e-09 37.0 0.0 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EGB11911.1 - 7.6e-08 32.5 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) SBDS PF01172.18 EGB11912.1 - 4.1e-29 100.5 0.0 5.6e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EGB11912.1 - 4.3e-13 49.3 0.0 7.4e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain Antimicrobial_2 PF08023.12 EGB11912.1 - 0.28 11.8 0.4 0.8 10.3 0.3 1.8 2 0 0 2 2 2 0 Frog antimicrobial peptide zf-C2H2_jaz PF12171.8 EGB11913.1 - 0.019 15.3 0.8 0.033 14.5 0.8 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGB11913.1 - 0.045 14.6 1.4 0.045 14.6 1.4 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.12 EGB11913.1 - 0.055 12.0 1.1 0.057 11.9 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) DUF3449 PF11931.8 EGB11913.1 - 0.061 13.1 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) zf-C2H2_2 PF12756.7 EGB11913.1 - 0.063 13.6 0.7 0.068 13.5 0.7 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Peptidase_C2 PF00648.21 EGB11914.1 - 2.4e-73 246.8 0.4 2.8e-73 246.5 0.4 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease LRR_6 PF13516.6 EGB11915.1 - 9.9e-11 40.8 1.9 1.9e-05 24.4 0.0 2.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 EGB11915.1 - 0.03 14.1 0.3 0.24 11.2 0.3 2.0 1 1 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.33 EGB11915.1 - 0.12 13.0 0.0 0.78 10.5 0.0 2.1 2 0 0 2 2 2 0 Leucine Rich Repeat Ion_trans PF00520.31 EGB11916.1 - 1.2e-23 83.6 1.3 2.7e-23 82.5 1.3 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB11916.1 - 1.5e-11 44.1 0.4 3.4e-11 42.9 0.4 1.6 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGB11916.1 - 4.3e-06 26.7 0.0 0.00027 20.9 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Rubis-subs-bind PF09273.11 EGB11917.1 - 1.9e-16 60.9 0.0 4.3e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EGB11917.1 - 9.1e-12 45.7 0.0 1.8e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 SET domain Glycos_transf_2 PF00535.26 EGB11918.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ion_trans PF00520.31 EGB11920.1 - 1.4e-17 63.8 6.7 2.8e-17 62.8 6.7 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB11920.1 - 7.6e-07 29.1 0.0 0.019 15.0 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGB11920.1 - 8.1e-07 28.9 3.7 2.2e-06 27.5 3.7 1.7 1 0 0 1 1 1 1 Ion channel Ank PF00023.30 EGB11921.1 - 8.2e-24 83.0 5.9 5.8e-09 36.0 0.3 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 EGB11921.1 - 9.5e-21 74.2 2.8 6e-10 39.6 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB11921.1 - 2.1e-19 69.3 8.6 7.1e-09 35.8 0.3 4.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB11921.1 - 6.3e-19 68.1 3.4 1.6e-09 38.1 0.2 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11921.1 - 9.2e-17 59.4 2.2 2.2e-05 24.5 0.1 4.9 5 0 0 5 5 5 4 Ankyrin repeat 5_nucleotid PF05761.14 EGB11922.1 - 4.7e-126 421.4 0.0 4.7e-124 414.8 0.0 2.0 1 1 0 1 1 1 1 5' nucleotidase family Cofilin_ADF PF00241.20 EGB11923.1 - 1.6e-21 76.3 0.0 1.8e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ADH_N PF08240.12 EGB11924.1 - 3.7e-24 84.7 3.4 7e-24 83.8 3.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGB11924.1 - 3e-10 40.2 3.4 3e-09 37.0 3.4 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGB11924.1 - 4.7e-07 29.3 0.1 8e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGB11924.1 - 0.0031 17.7 0.2 0.0048 17.1 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGB11924.1 - 0.0034 17.1 0.3 0.0054 16.4 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EGB11924.1 - 0.0072 15.7 3.3 0.013 14.8 3.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 EGB11924.1 - 0.0083 16.6 0.2 0.018 15.5 0.2 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain Shikimate_DH PF01488.20 EGB11924.1 - 0.024 14.7 0.9 0.077 13.1 0.2 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGB11924.1 - 0.066 13.5 1.4 0.16 12.2 1.4 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 EGB11924.1 - 0.069 13.7 2.8 0.098 13.2 0.7 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.21 EGB11924.1 - 0.1 12.3 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 EGB11924.1 - 0.18 12.3 0.6 0.32 11.5 0.6 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EGB11924.1 - 0.42 10.5 4.7 0.11 12.4 1.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RING_2 PF13639.6 EGB11925.1 - 1.7e-08 34.7 9.4 3.9e-08 33.5 9.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGB11925.1 - 3.2e-05 23.7 8.9 6.6e-05 22.7 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGB11925.1 - 0.00048 20.4 8.6 0.001 19.3 8.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGB11925.1 - 0.01 15.8 5.5 0.022 14.8 5.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EGB11925.1 - 0.016 15.0 7.6 0.031 14.1 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGB11925.1 - 0.018 14.9 6.9 0.035 14.0 6.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGB11925.1 - 0.1 12.8 4.4 0.2 11.8 4.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EGB11925.1 - 0.15 11.8 2.6 0.31 10.8 2.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_1 PF14446.6 EGB11925.1 - 0.65 10.0 6.6 1.4 8.9 3.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 EGB11925.1 - 4.2 7.6 9.4 8.3 6.6 9.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_5 PF14634.6 EGB11925.1 - 4.9 7.2 7.3 10 6.2 7.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C2HC_2 PF13913.6 EGB11926.1 - 2.8e-18 65.4 4.2 5.1e-10 39.0 0.2 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EGB11926.1 - 0.002 18.8 2.1 2.5 9.2 0.0 2.6 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGB11926.1 - 0.0039 17.6 1.7 2.3 8.8 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-FCS PF06467.14 EGB11926.1 - 0.0087 16.0 0.7 4.6 7.3 0.1 2.7 3 0 0 3 3 3 2 MYM-type Zinc finger with FCS sequence motif FYVE PF01363.21 EGB11926.1 - 0.023 14.8 0.9 5.6 7.2 0.1 2.2 2 0 0 2 2 2 0 FYVE zinc finger DUF1178 PF06676.11 EGB11926.1 - 0.027 14.9 0.3 0.034 14.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) RNF220 PF15926.5 EGB11926.1 - 0.032 13.9 0.0 0.051 13.2 0.0 1.4 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 c-SKI_SMAD_bind PF08782.10 EGB11926.1 - 0.039 14.2 0.3 0.094 12.9 0.0 1.7 2 0 0 2 2 2 0 c-SKI Smad4 binding domain DUF2256 PF10013.9 EGB11926.1 - 0.05 13.7 1.3 4.9 7.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CHCC PF10276.9 EGB11926.1 - 0.075 13.1 0.2 3.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain FpoO PF10621.9 EGB11926.1 - 0.078 13.3 0.2 5.1 7.4 0.0 2.1 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO zf-CpG_bind_C PF12269.8 EGB11926.1 - 0.089 12.6 0.2 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain C5HCH PF17982.1 EGB11926.1 - 0.099 12.8 2.8 8.3 6.7 0.6 2.4 2 1 0 2 2 2 0 NSD Cys-His rich domain UBZ_FAAP20 PF15750.5 EGB11926.1 - 0.13 12.3 3.0 2.8 8.0 0.4 2.5 2 1 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-BED PF02892.15 EGB11926.1 - 0.25 11.4 2.5 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 BED zinc finger Sgf11 PF08209.11 EGB11926.1 - 1.7 8.3 6.5 9 6.0 1.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) ABC_tran PF00005.27 EGB11927.1 - 9.5e-18 65.0 0.0 1.4e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB11927.1 - 5.2e-06 26.5 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB11927.1 - 3.1e-05 24.4 0.1 4.3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGB11927.1 - 0.0049 16.6 0.3 0.01 15.6 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB11927.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB11927.1 - 0.025 14.5 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGB11927.1 - 0.026 15.1 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGB11927.1 - 0.049 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGB11927.1 - 0.083 13.1 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 EGB11927.1 - 0.093 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein SMC_N PF02463.19 EGB11927.1 - 0.1 12.0 0.1 0.24 10.8 0.1 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EGB11927.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB11927.1 - 0.16 12.5 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.20 EGB11928.1 - 1.4e-41 142.0 2.1 1.4e-41 142.0 2.1 3.0 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGB11928.1 - 1.1e-32 113.2 0.1 1.1e-32 113.2 0.1 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGB11928.1 - 7.9e-17 62.2 5.4 1.5e-13 51.5 2.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGB11928.1 - 2.7e-14 53.0 0.0 8.3e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGB11928.1 - 8e-13 47.9 0.0 1.7e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FliMN_C PF01052.20 EGB11928.1 - 0.015 15.3 0.5 0.045 13.8 0.5 1.8 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Hydrolase_3 PF08282.12 EGB11928.1 - 0.038 13.7 0.2 0.069 12.9 0.2 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3382 PF11862.8 EGB11928.1 - 0.42 10.9 4.5 0.2 12.0 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Peptidase_C1 PF00112.23 EGB11929.1 - 1.1e-63 215.2 6.6 1.5e-63 214.8 6.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB11929.1 - 1.2e-09 38.5 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB11929.1 - 2.1e-06 26.8 1.7 0.00077 18.3 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Frag1 PF10277.9 EGB11931.1 - 3.9e-12 46.2 11.4 8.1e-07 28.8 2.5 3.1 2 1 0 2 2 2 2 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 EGB11931.1 - 3.4e-05 23.5 11.2 3.4e-05 23.5 11.2 3.9 3 2 2 5 5 5 2 Protein of unknown function (DUF998) Aldedh PF00171.22 EGB11932.1 - 5.4e-148 493.3 0.1 6.1e-148 493.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lipase_GDSL_2 PF13472.6 EGB11932.1 - 0.0021 18.5 0.9 0.0021 18.5 0.9 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family LuxC PF05893.14 EGB11932.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.3 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Sigma70_r4_2 PF08281.12 EGB11934.1 - 0.14 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HSP70 PF00012.20 EGB11935.1 - 2.5e-241 802.1 1.5 2.8e-241 801.9 1.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGB11935.1 - 1.7e-13 50.1 0.4 1.2e-12 47.4 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein GLE1 PF07817.13 EGB11935.1 - 0.065 12.4 0.1 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 GLE1-like protein PPR_2 PF13041.6 EGB11936.1 - 2.8e-15 56.2 0.0 1.3e-09 38.1 0.0 3.2 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.20 EGB11936.1 - 5.8e-14 51.3 0.1 0.00018 21.5 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 EGB11936.1 - 1.5e-13 50.6 0.0 1.3e-07 31.6 0.0 3.3 1 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGB11936.1 - 4.7e-09 35.8 0.0 0.014 15.1 0.0 4.3 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EGB11936.1 - 3.5e-05 23.3 0.0 5.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Paf67 PF10255.9 EGB11937.1 - 1.4e-108 363.5 0.0 1.7e-108 363.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EGB11937.1 - 0.017 15.2 1.3 0.062 13.4 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB11937.1 - 0.066 13.1 0.2 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Nop52 PF05997.12 EGB11938.1 - 6.1e-40 137.3 0.0 1.3e-39 136.2 0.0 1.5 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Acyl_transf_3 PF01757.22 EGB11938.1 - 2.3e-22 79.5 32.7 7.8e-22 77.8 32.7 1.8 1 1 0 1 1 1 1 Acyltransferase family TPR_2 PF07719.17 EGB11938.1 - 1.5e-11 43.5 10.8 0.0013 18.7 0.5 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB11938.1 - 1.3e-10 40.8 11.0 0.0083 15.8 0.0 6.4 4 1 2 6 6 6 4 TPR repeat Methyltransf_25 PF13649.6 EGB11938.1 - 1.6e-09 38.3 0.2 5.3e-09 36.7 0.2 2.0 1 0 0 1 1 1 1 Methyltransferase domain TPR_1 PF00515.28 EGB11938.1 - 2.9e-09 36.4 2.9 0.0089 15.8 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat Methyltransf_11 PF08241.12 EGB11938.1 - 4.3e-09 36.9 0.2 1.2e-08 35.5 0.2 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB11938.1 - 6.6e-09 36.4 0.1 1.6e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPR_8 PF13181.6 EGB11938.1 - 6.3e-08 32.2 0.1 0.91 9.9 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11938.1 - 2.2e-07 30.4 6.3 1.7 8.8 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Methyltransf_31 PF13847.6 EGB11938.1 - 1e-06 28.7 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPR_12 PF13424.6 EGB11938.1 - 8.4e-06 26.0 16.7 0.0066 16.7 4.5 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11938.1 - 3.3e-05 24.3 16.3 0.062 13.8 0.1 5.1 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11938.1 - 0.00032 21.3 35.4 0.0038 17.8 6.4 7.1 4 1 2 7 7 5 3 Tetratricopeptide repeat NodS PF05401.11 EGB11938.1 - 0.00045 19.9 0.0 0.0015 18.2 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 EGB11938.1 - 0.0033 17.3 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ANAPC3 PF12895.7 EGB11938.1 - 0.0044 17.2 0.1 0.32 11.3 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 MTS PF05175.14 EGB11938.1 - 0.0059 16.2 0.1 0.015 14.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase small domain TPR_14 PF13428.6 EGB11938.1 - 0.09 13.6 54.2 0.036 14.9 1.3 8.9 5 1 5 10 10 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11938.1 - 1 10.2 6.4 83 4.1 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat PBP1_TM PF14812.6 EGB11938.1 - 1.8 9.0 10.2 1.1 9.7 2.7 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EGB11938.1 - 2.4 8.4 7.6 0.32 11.3 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PGA2 PF07543.12 EGB11938.1 - 7.1 6.6 13.1 7.2 6.6 9.5 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 V-ATPase_C PF03223.15 EGB11939.1 - 9.6e-97 324.7 0.0 1.1e-96 324.4 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Cep57_MT_bd PF06657.13 EGB11939.1 - 0.094 13.2 0.3 0.96 9.9 0.0 2.6 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 4HBT_3 PF13622.6 EGB11940.1 - 3.3e-41 142.2 3.1 4.4e-41 141.8 3.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EGB11940.1 - 2.8e-20 72.5 0.1 2.6e-15 56.5 0.0 3.3 3 1 0 3 3 3 2 Acyl-CoA thioesterase Synaptobrevin PF00957.21 EGB11941.1 - 3.9e-21 74.6 2.9 4.1e-21 74.6 2.9 1.0 1 0 0 1 1 1 1 Synaptobrevin Polyketide_cyc2 PF10604.9 EGB11942.1 - 6.3e-07 29.8 0.1 1.1e-06 29.0 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EGB11942.1 - 4.6e-06 26.9 0.1 8.8e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_C1 PF00112.23 EGB11943.1 - 1.2e-16 61.4 0.1 1.3e-16 61.4 0.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease EGF_CA PF07645.15 EGB11943.1 - 0.075 13.3 1.4 0.12 12.6 1.4 1.3 1 0 0 1 1 1 0 Calcium-binding EGF domain Peptidase_C1 PF00112.23 EGB11944.1 - 1.1e-20 74.7 0.6 1.2e-20 74.6 0.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB11944.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Peptidase C1-like family Thioredoxin PF00085.20 EGB11945.1 - 2.2e-06 27.6 0.0 2.4e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGB11945.1 - 8.5e-05 22.8 0.0 0.21 11.9 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB11945.1 - 0.019 15.4 0.1 0.046 14.2 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.10 EGB11945.1 - 0.03 14.0 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 EGB11945.1 - 0.032 14.4 0.1 0.039 14.1 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 EGB11945.1 - 0.078 12.8 0.0 0.08 12.7 0.0 1.0 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 EGB11945.1 - 0.084 12.8 0.0 0.084 12.8 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 EGB11945.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.6 EGB11945.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin FR47 PF08445.10 EGB11945.1 - 0.21 11.6 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Methyltransf_25 PF13649.6 EGB11946.1 - 0.0022 18.6 0.3 0.013 16.2 0.1 2.6 2 0 0 2 2 2 1 Methyltransferase domain Ribosomal_L4 PF00573.22 EGB11946.1 - 0.31 10.7 1.1 0.62 9.7 1.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family TPR_10 PF13374.6 EGB11946.1 - 2 8.4 15.6 24 4.9 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11946.1 - 3.1 8.2 22.3 5.3 7.4 0.8 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGB11947.1 - 2.3e-27 95.4 3.4 8.2e-11 42.3 0.5 4.6 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGB11947.1 - 1.5e-22 78.9 22.9 0.0024 18.3 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EGB11947.1 - 3e-22 78.7 9.4 0.00011 22.7 0.1 6.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB11947.1 - 1.3e-17 62.1 10.5 0.00094 19.5 0.0 8.0 7 0 0 7 7 7 5 Ankyrin repeat VCBS PF13517.6 EGB11947.1 - 5.9e-16 58.8 29.2 8.7e-08 32.7 7.2 4.9 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ank_5 PF13857.6 EGB11947.1 - 5.4e-15 55.3 23.3 0.00015 22.0 0.6 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) FG-GAP PF01839.23 EGB11947.1 - 1.3e-10 41.2 37.7 0.001 19.1 4.4 5.6 5 0 0 5 5 5 4 FG-GAP repeat WW PF00397.26 EGB11947.1 - 5.5e-05 23.2 0.4 0.00012 22.1 0.4 1.5 1 0 0 1 1 1 1 WW domain BBS2_Mid PF14783.6 EGB11947.1 - 0.14 12.2 0.0 1.1e+02 2.9 0.0 3.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Laminin_B PF00052.18 EGB11948.1 - 8.1e-08 32.3 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF550 PF04447.12 EGB11948.1 - 0.029 14.5 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Inositol_P PF00459.25 EGB11949.1 - 5.4e-49 167.1 0.0 6e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Methyltransf_8 PF05148.15 EGB11950.1 - 8.3e-69 231.8 0.0 9.5e-69 231.6 0.0 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGB11950.1 - 9.3e-08 32.6 0.1 5.4e-07 30.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB11950.1 - 4.4e-07 30.5 0.1 0.00011 22.8 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB11950.1 - 0.00015 21.6 0.0 0.067 13.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 EGB11950.1 - 0.00095 18.8 0.0 0.43 10.1 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase small domain MetW PF07021.12 EGB11950.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Hydrolase_4 PF12146.8 EGB11951.1 - 3.3e-18 65.8 0.2 3.1e-17 62.6 0.1 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB11951.1 - 8e-12 45.3 0.2 1.5e-11 44.5 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB11951.1 - 0.002 17.6 0.0 0.22 11.0 0.1 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGB11951.1 - 0.076 12.9 1.4 0.38 10.6 0.9 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Dynein_C PF18199.1 EGB11952.1 - 2.1e-07 30.5 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain HECT PF00632.25 EGB11954.1 - 1.5e-31 110.0 0.0 1.6e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4239 PF14023.6 EGB11955.1 - 2.7e-07 30.5 3.2 5.3e-06 26.3 3.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4239) Aldo_ket_red PF00248.21 EGB11956.1 - 6.7e-34 117.4 0.0 1e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family TRP PF06011.12 EGB11956.1 - 0.25 10.0 0.3 0.4 9.4 0.3 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel FA_hydroxylase PF04116.13 EGB11957.1 - 4.4e-20 72.4 20.9 4.4e-20 72.4 20.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Myosin_head PF00063.21 EGB11958.1 - 1.1e-194 648.5 0.0 1.2e-194 648.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB11958.1 - 0.0011 19.3 1.6 0.033 14.6 0.9 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB11958.1 - 0.055 13.7 0.0 0.23 11.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGB11958.1 - 0.24 10.6 1.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 EGB11958.1 - 0.27 11.8 0.9 1.4 9.4 0.8 2.1 1 1 0 1 1 1 0 ABC transporter Aminotran_1_2 PF00155.21 EGB11959.1 - 9.2e-71 238.9 0.0 1e-70 238.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DAO PF01266.24 EGB11960.1 - 3.4e-26 92.7 20.5 7.9e-23 81.6 9.6 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase DHDPS PF00701.22 EGB11960.1 - 2.3e-22 79.1 0.0 3.5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FAD_binding_2 PF00890.24 EGB11960.1 - 3.1e-07 29.8 10.9 7.7e-07 28.5 10.9 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGB11960.1 - 0.0097 16.1 2.0 0.066 13.4 2.0 2.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGB11960.1 - 0.015 14.4 0.4 0.015 14.4 0.4 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EGB11960.1 - 0.031 13.5 1.5 0.042 13.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGB11960.1 - 3.3 6.4 4.3 22 3.7 0.9 2.2 2 0 0 2 2 2 0 Tryptophan halogenase ASH PF15780.5 EGB11961.1 - 5.6e-38 129.1 17.9 2.9e-05 24.2 0.3 14.1 16 0 0 16 16 16 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 EGB11961.1 - 6e-12 45.7 7.8 0.012 15.8 0.1 9.3 9 0 0 9 9 9 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 EGB11961.1 - 2.4e-11 43.4 0.2 0.071 13.0 0.0 6.5 7 0 0 7 7 7 3 MSP (Major sperm protein) domain PapD-like PF14874.6 EGB11961.1 - 1.4e-08 34.8 0.7 0.089 13.0 0.0 5.7 6 0 0 6 6 6 2 Flagellar-associated PapD-like DUF5001 PF16392.5 EGB11961.1 - 1.5e-05 24.8 0.0 0.61 10.0 0.0 4.5 4 0 0 4 4 4 2 Ig-like domain MYCBPAP PF14646.6 EGB11961.1 - 0.00017 20.7 0.0 0.76 8.6 0.0 3.2 4 0 0 4 4 4 2 MYCBP-associated protein family P_C PF06640.11 EGB11961.1 - 1.6 8.8 7.0 7.5 6.6 7.0 2.2 1 0 0 1 1 1 0 P protein C-terminus Aldo_ket_red PF00248.21 EGB11962.1 - 2.7e-69 233.6 0.0 3.3e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PGI PF00342.19 EGB11963.1 - 9.7e-55 186.0 0.0 1.3e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase 2OG-FeII_Oxy PF03171.20 EGB11964.1 - 2.6e-19 69.6 0.0 4.5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DAP3 PF10236.9 EGB11964.1 - 7.4e-16 58.2 0.0 1.9e-15 56.9 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DIOX_N PF14226.6 EGB11964.1 - 8.1e-16 58.8 0.0 1.5e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AAA_16 PF13191.6 EGB11964.1 - 0.0045 17.4 1.1 0.014 15.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.7 EGB11964.1 - 0.047 12.6 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.6 EGB11964.1 - 0.07 12.7 0.9 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGB11964.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGB11964.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain POTRA PF07244.15 EGB11964.1 - 0.17 12.5 0.1 0.6 10.7 0.0 1.9 2 0 0 2 2 2 0 Surface antigen variable number repeat Aminotran_5 PF00266.19 EGB11966.1 - 2e-58 198.1 0.0 2.4e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGB11966.1 - 0.0041 16.5 4.2 0.0041 16.5 4.2 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Sigma70_ner PF04546.13 EGB11967.1 - 0.023 14.6 0.0 0.41 10.5 0.0 2.0 1 1 0 2 2 2 0 Sigma-70, non-essential region ATP-synt_F PF01990.17 EGB11968.1 - 3.8e-24 84.8 0.9 6.4e-13 48.8 0.1 2.0 2 0 0 2 2 2 2 ATP synthase (F/14-kDa) subunit Kinesin PF00225.23 EGB11969.1 - 3.2e-81 272.9 0.0 3.6e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB11969.1 - 1.2e-15 57.7 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding adh_short_C2 PF13561.6 EGB11971.1 - 2.1e-51 174.7 1.4 2.5e-51 174.5 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB11971.1 - 2.7e-42 144.5 2.5 3.1e-42 144.2 2.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB11971.1 - 4.7e-10 39.7 1.8 6.7e-10 39.2 1.8 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EGB11971.1 - 2.9e-07 30.5 3.5 5.6e-07 29.6 3.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 EGB11971.1 - 0.088 12.9 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MccV PF17508.2 EGB11971.1 - 8.4 7.0 10.5 0.79 10.3 1.3 2.6 1 1 1 2 2 2 0 Microcin V bacteriocin Methyltransf_31 PF13847.6 EGB11972.1 - 2.4e-18 66.4 0.0 3e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB11972.1 - 6.5e-14 52.4 0.1 1.2e-13 51.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB11972.1 - 2.5e-12 47.3 0.1 4.6e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB11972.1 - 1.6e-09 37.8 0.0 2.8e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB11972.1 - 2.1e-08 34.8 0.0 4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB11972.1 - 8.9e-07 28.5 0.0 2.1e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGB11972.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGB11972.1 - 4.2e-05 23.1 0.0 6.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_20 PF12147.8 EGB11972.1 - 0.00017 20.9 0.0 0.00023 20.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 EGB11972.1 - 0.00018 21.2 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 EGB11972.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.19 EGB11972.1 - 0.038 14.1 0.0 0.084 13.0 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGB11972.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EGB11972.1 - 0.16 10.8 0.0 0.26 10.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) GST_C_2 PF13410.6 EGB11973.1 - 2.7e-12 46.5 2.8 3.1e-12 46.3 1.3 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGB11973.1 - 5.6e-12 45.8 0.0 2.8e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB11973.1 - 5.5e-07 29.7 0.0 8.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGB11973.1 - 2.6e-05 24.3 0.0 3.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB11973.1 - 0.00038 20.8 0.0 3.9 8.0 0.0 3.4 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EGB11973.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin tRNA-synt_1c PF00749.21 EGB11974.1 - 4.2e-52 177.0 0.0 4.6e-29 101.3 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 EGB11974.1 - 0.0086 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) DUF1115 PF06544.12 EGB11975.1 - 4.1e-34 117.8 1.0 1.4e-33 116.0 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 EGB11975.1 - 8.8e-12 45.2 0.9 8.8e-12 45.2 0.9 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) E1-E2_ATPase PF00122.20 EGB11976.1 - 1.2e-43 148.8 1.0 1.2e-43 148.8 1.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGB11976.1 - 4.9e-16 59.7 6.5 1.4e-15 58.1 6.5 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGB11976.1 - 1.6e-11 43.7 0.0 3.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGB11976.1 - 0.00017 21.4 0.5 0.00027 20.8 0.1 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGB11976.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) CPSase_L_D2 PF02786.17 EGB11977.1 - 2.1e-72 243.1 0.1 3.7e-72 242.2 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EGB11977.1 - 6.4e-62 208.8 0.0 1e-61 208.2 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EGB11977.1 - 1.9e-35 121.7 0.1 6.5e-35 120.0 0.1 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGB11977.1 - 6.7e-33 113.0 0.0 2.1e-32 111.4 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGB11977.1 - 2.4e-24 86.3 0.0 5.2e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGB11977.1 - 7.9e-19 67.3 3.2 1.6e-18 66.3 3.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGB11977.1 - 1.9e-12 46.8 1.7 1.7e-07 30.9 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EGB11977.1 - 1.4e-06 29.0 1.1 0.02 15.6 0.1 2.9 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EGB11977.1 - 2.2e-06 27.1 0.8 0.0038 16.5 0.1 3.0 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp PF02222.22 EGB11977.1 - 1.5e-05 24.6 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGB11977.1 - 0.00012 21.7 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus NQRA PF05896.11 EGB11977.1 - 0.00079 18.9 0.2 0.0014 18.1 0.2 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_3 PF02655.14 EGB11977.1 - 0.0021 18.1 0.0 0.0061 16.6 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EGB11977.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 EGB11977.1 - 0.034 13.9 0.1 0.08 12.7 0.0 1.6 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PYNP_C PF07831.13 EGB11977.1 - 0.052 13.2 0.1 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.19 EGB11977.1 - 0.11 12.4 0.5 0.46 10.4 0.5 2.0 1 1 0 1 1 1 0 Glycine cleavage H-protein cNMP_binding PF00027.29 EGB11978.1 - 6.5e-30 103.1 0.0 3.8e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGB11979.1 - 7.2e-58 196.0 0.0 8.1e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB11979.1 - 4.3e-31 108.1 0.0 5.3e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB11979.1 - 7e-06 26.1 0.7 0.0005 20.1 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB11979.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Lum_binding PF00677.17 EGB11980.1 - 5.4e-44 148.1 0.3 2.5e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Corona_M PF01635.18 EGB11980.1 - 0.036 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Nuc_sug_transp PF04142.15 EGB11982.1 - 1.5e-06 27.6 1.2 1.5e-06 27.6 1.2 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter CRT-like PF08627.10 EGB11982.1 - 5.4e-05 22.3 12.5 0.0091 15.0 12.5 2.2 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 EGB11982.1 - 0.024 13.8 8.2 0.057 12.6 8.1 1.6 1 1 0 1 1 1 0 UAA transporter family Ion_trans_2 PF07885.16 EGB11982.1 - 0.053 13.5 0.7 0.053 13.5 0.7 2.8 3 0 0 3 3 3 0 Ion channel Caenor_Her-1 PF09232.10 EGB11982.1 - 0.29 11.3 1.0 0.52 10.5 0.5 1.5 1 1 0 1 1 1 0 Caenorhabditis elegans Her-1 Tetraspanin PF00335.20 EGB11982.1 - 0.5 10.0 6.3 0.055 13.2 0.4 2.3 2 1 1 3 3 3 0 Tetraspanin family EamA PF00892.20 EGB11982.1 - 0.54 10.4 15.7 0.68 10.1 2.4 3.3 2 1 0 2 2 2 0 EamA-like transporter family TPT PF03151.16 EGB11982.1 - 1.7 7.9 15.8 0.66 9.3 11.9 2.2 2 1 0 2 2 2 0 Triose-phosphate Transporter family Phage_holin_3_1 PF05106.12 EGB11982.1 - 2.5 8.6 7.3 3.1 8.3 2.4 2.5 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) 4HB_MCP_1 PF12729.7 EGB11982.1 - 9.9 5.7 7.2 7.8 6.0 0.4 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction ANAPC3 PF12895.7 EGB11983.1 - 3.2e-12 46.5 29.4 8.3e-06 25.9 3.5 4.6 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGB11983.1 - 1e-08 34.6 22.8 0.026 14.6 0.6 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGB11983.1 - 1.1e-08 35.4 26.8 9.7e-05 22.8 0.9 7.0 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGB11983.1 - 0.00013 22.5 13.7 0.0049 17.5 1.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB11983.1 - 0.0003 21.2 13.6 0.067 13.9 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB11983.1 - 0.0011 19.1 12.0 0.0013 18.8 1.0 4.9 7 0 0 7 7 6 1 Tetratricopeptide repeat FMN_red PF03358.15 EGB11983.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Fis1_TPR_C PF14853.6 EGB11983.1 - 0.087 12.9 3.3 0.67 10.1 0.2 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 EGB11983.1 - 0.15 11.9 22.6 0.073 12.9 0.7 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB11983.1 - 0.57 10.5 18.2 1.4 9.3 1.1 6.1 6 2 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB11983.1 - 1.6 8.9 6.5 12 6.2 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Na_H_antiporter PF03553.14 EGB11984.1 - 1.6e-39 135.9 10.8 2.5e-38 132.0 6.0 2.2 1 1 1 2 2 2 2 Na+/H+ antiporter family DcuC PF03606.15 EGB11984.1 - 0.00031 19.3 13.3 0.046 12.2 9.7 2.4 2 0 0 2 2 2 2 C4-dicarboxylate anaerobic carrier Exo_endo_phos PF03372.23 EGB11985.1 - 2.8e-06 27.0 2.3 1.1e-05 25.0 2.3 2.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_transf_18 PF15024.6 EGB11985.1 - 0.37 9.3 6.2 3.1 6.3 6.2 2.0 1 1 0 1 1 1 0 Glycosyltransferase family 18 ABM PF03992.16 EGB11986.1 - 4.1e-17 62.1 1.1 1.2e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase HALZ PF02183.18 EGB11986.1 - 0.094 13.0 2.3 0.18 12.0 0.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cyclin_N PF00134.23 EGB11987.1 - 1.1e-06 28.4 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGB11987.1 - 2.3e-06 28.1 0.0 3.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Actin PF00022.19 EGB11988.1 - 5.8e-101 338.0 0.0 2.4e-100 336.0 0.0 1.8 1 1 0 1 1 1 1 Actin LCAT PF02450.15 EGB11988.1 - 4e-29 102.0 0.0 2.8e-27 95.9 0.0 2.3 3 0 0 3 3 3 2 Lecithin:cholesterol acyltransferase ThiG PF05690.14 EGB11989.1 - 2.6e-102 341.3 4.1 3.1e-102 341.1 4.1 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EGB11989.1 - 1.7e-05 24.0 1.2 3.3e-05 23.1 1.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EGB11989.1 - 7.3e-05 22.3 0.1 0.00021 20.8 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 EGB11989.1 - 0.00087 18.5 0.8 0.019 14.1 0.1 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 EGB11989.1 - 0.0017 17.5 2.0 0.0022 17.1 0.8 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Dus PF01207.17 EGB11989.1 - 0.0018 17.5 0.0 0.61 9.1 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Glu_synthase PF01645.17 EGB11989.1 - 0.031 13.4 0.6 0.07 12.3 0.1 1.7 2 0 0 2 2 2 0 Conserved region in glutamate synthase SBBP PF06739.11 EGB11990.1 - 0.00016 21.6 11.0 0.034 14.1 0.0 6.4 7 0 0 7 7 7 1 Beta-propeller repeat Cupin_8 PF13621.6 EGB11990.1 - 0.00069 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain PQQ PF01011.21 EGB11990.1 - 0.023 14.6 1.4 2.1 8.4 0.1 3.4 2 0 0 2 2 2 0 PQQ enzyme repeat MMR_HSR1 PF01926.23 EGB11991.1 - 5.6e-14 52.2 0.0 1.3e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB11991.1 - 2.5e-06 27.1 0.0 0.003 17.1 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGB11991.1 - 2.6e-05 24.2 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB11991.1 - 0.00045 20.7 2.0 0.013 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 EGB11991.1 - 0.0025 16.9 0.1 0.059 12.3 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Chloroa_b-bind PF00504.21 EGB11992.1 - 2e-33 116.2 0.0 3.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein IMS PF00817.20 EGB11993.1 - 5.2e-38 130.4 0.0 5.9e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 impB/mucB/samB family Glyco_transf_90 PF05686.12 EGB11994.1 - 2.1e-08 33.5 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Aminotran_1_2 PF00155.21 EGB11995.1 - 7.4e-52 176.7 0.0 8.8e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ephrin_rec_like PF07699.13 EGB11996.1 - 8.7e-17 60.6 15.6 9.7e-09 34.9 1.7 2.1 2 0 0 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 EGB11996.1 - 0.017 15.1 5.2 1.9 8.5 0.3 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EGB11996.1 - 0.16 12.4 5.3 9 6.8 0.7 3.1 2 2 0 2 2 2 0 TNFR/NGFR cysteine-rich region Laminin_EGF PF00053.24 EGB11996.1 - 1.1 9.5 12.4 11 6.2 6.1 2.4 1 1 1 2 2 2 0 Laminin EGF domain Ephrin_rec_like PF07699.13 EGB11997.1 - 3.1e-37 126.1 49.4 6.9e-09 35.3 5.0 5.9 4 1 2 6 6 6 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB11997.1 - 4.6e-07 30.1 28.0 0.25 11.8 3.4 7.7 5 4 2 7 7 7 5 TNFR/NGFR cysteine-rich region VSP PF03302.13 EGB11997.1 - 0.28 10.0 52.9 2.2 7.1 13.3 3.4 1 1 2 3 3 3 0 Giardia variant-specific surface protein Laminin_EGF PF00053.24 EGB11997.1 - 0.43 10.8 43.3 5.3 7.3 2.8 7.1 3 2 1 5 5 5 0 Laminin EGF domain DnaJ PF00226.31 EGB11998.1 - 6.1e-24 83.9 0.7 6.7e-24 83.8 0.7 1.0 1 0 0 1 1 1 1 DnaJ domain Prefoldin_2 PF01920.20 EGB11999.1 - 7.8e-19 67.6 0.6 9.1e-19 67.4 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.11 EGB11999.1 - 0.0047 17.3 1.3 0.093 13.1 0.4 2.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) HGD-D PF06050.13 EGB11999.1 - 0.035 13.9 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component ABC1 PF03109.16 EGB11999.1 - 0.038 14.2 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family GTP-bdg_M PF16360.5 EGB11999.1 - 0.12 13.0 0.2 0.32 11.6 0.1 1.8 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region GPHR_N PF12537.8 EGB11999.1 - 0.12 12.5 0.0 3.4 7.8 0.0 2.2 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Spc24 PF08286.11 EGB11999.1 - 0.16 12.3 1.6 0.24 11.6 0.8 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_17 PF13431.6 EGB12000.1 - 8.8e-13 47.7 7.3 0.0042 17.4 0.5 4.1 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12000.1 - 2.8e-12 45.9 11.2 0.00013 21.7 0.3 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB12000.1 - 1.9e-10 40.3 11.4 5.9e-05 22.7 0.1 4.1 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.17 EGB12000.1 - 1.2e-09 37.6 18.7 0.0013 18.6 0.3 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGB12000.1 - 3.1e-08 34.1 20.1 3.7e-05 24.3 7.3 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGB12000.1 - 3.9e-08 32.9 1.3 0.00022 21.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB12000.1 - 8.2e-05 22.8 16.6 0.0013 19.0 3.0 3.1 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGB12000.1 - 0.00012 22.6 13.5 0.0055 17.4 0.4 4.3 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGB12000.1 - 0.00097 19.0 6.7 1.3 9.2 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGB12000.1 - 0.0073 16.9 3.6 0.34 11.6 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGB12000.1 - 0.016 14.4 3.7 0.21 10.8 0.9 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB12000.1 - 0.11 12.4 12.6 0.69 9.9 0.5 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB12000.1 - 0.26 11.8 11.2 9.8 6.8 3.2 3.3 1 1 3 4 4 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EGB12001.1 - 9.2e-39 133.4 0.0 2.8e-37 128.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 EGB12001.1 - 0.067 13.5 0.0 31 4.8 0.0 3.2 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain His_Phos_1 PF00300.22 EGB12002.1 - 3.1e-25 89.0 0.2 5.9e-25 88.1 0.2 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF179 PF02622.15 EGB12003.1 - 1.5e-15 57.5 0.0 9.4e-15 54.9 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 NAD_kinase PF01513.21 EGB12003.1 - 3.4e-07 29.8 0.1 0.0032 16.7 0.0 2.3 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 EGB12003.1 - 0.028 14.1 0.2 0.065 12.9 0.2 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain 2OG-FeII_Oxy_3 PF13640.6 EGB12004.1 - 1e-13 52.0 0.0 1.2e-13 51.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB12004.1 - 0.0011 19.5 0.0 0.0013 19.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 EGB12004.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Ribosomal_L7Ae PF01248.26 EGB12005.1 - 0.0055 16.4 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.22 EGB12005.1 - 0.12 12.2 0.0 13 5.7 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PfkB PF00294.24 EGB12006.1 - 9e-26 90.9 1.3 1.2e-25 90.5 1.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Pkinase PF00069.25 EGB12007.1 - 1.3e-55 188.6 0.0 1.2e-54 185.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12007.1 - 1.1e-38 133.1 0.0 1.5e-35 122.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGB12007.1 - 1.1e-06 28.2 0.0 3.2e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGB12007.1 - 6.7e-06 25.1 0.0 8.9e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB12007.1 - 0.021 14.7 0.2 0.2 11.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGB12007.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Nudc_N PF14050.6 EGB12008.1 - 8.5e-15 54.5 0.4 1.7e-14 53.5 0.4 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 EGB12008.1 - 3.7e-13 50.3 0.0 8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 CS domain Na_Ca_ex PF01699.24 EGB12009.1 - 1e-47 161.9 34.4 4.3e-29 101.4 13.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Phyto_Pns9_10 PF05878.11 EGB12009.1 - 0.22 10.7 0.1 0.31 10.1 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 TraX PF05857.11 EGB12009.1 - 2.6 8.0 11.4 0.42 10.6 1.8 2.8 3 0 0 3 3 3 0 TraX protein AGH PF17558.2 EGB12012.1 - 0.17 12.1 1.7 8.5 6.6 0.4 2.8 2 1 1 3 3 3 0 Androgenic gland hormone PBP1_TM PF14812.6 EGB12012.1 - 0.24 11.8 9.1 0.82 10.1 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_1 PF00036.32 EGB12013.1 - 3.9e-17 60.4 5.2 1.3e-08 33.7 1.7 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB12013.1 - 8.9e-14 50.2 1.4 4e-06 26.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB12013.1 - 1.2e-13 51.3 0.2 1.3e-13 51.2 0.2 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGB12013.1 - 1.4e-12 47.2 5.4 1e-10 41.3 1.1 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB12013.1 - 2.1e-12 45.9 3.7 1.3e-05 24.4 0.9 2.1 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EGB12013.1 - 1.9e-05 24.6 1.4 0.064 13.2 0.0 2.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGB12013.1 - 0.0012 19.1 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain Lip_prot_lig_C PF10437.9 EGB12013.1 - 0.084 12.9 0.0 0.11 12.5 0.0 1.2 1 1 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus cNMP_binding PF00027.29 EGB12014.1 - 9.1e-13 48.1 0.0 2.7e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGB12014.1 - 4e-12 45.9 14.6 6.2e-12 45.3 14.6 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 EGB12016.1 - 1.2e-35 121.9 0.8 8.3e-11 42.3 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB12016.1 - 7.9e-30 99.6 1.0 0.00055 20.2 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EGB12016.1 - 7.4e-26 90.2 0.2 1.9e-06 28.3 0.0 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB12016.1 - 9e-24 83.2 2.3 3.8e-09 36.6 0.0 6.0 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EGB12016.1 - 5.5e-23 80.3 10.0 0.00032 21.0 0.1 7.8 8 0 0 8 8 8 5 Ankyrin repeat DUF1967 PF09269.11 EGB12016.1 - 0.2 11.6 1.7 7.6 6.6 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1967) Hydrolase_6 PF13344.6 EGB12017.1 - 2.2e-20 72.7 0.0 4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB12017.1 - 1.4e-14 54.9 0.0 2.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB12017.1 - 1.3e-12 47.5 0.4 2.8e-12 46.5 0.4 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGB12017.1 - 8.6e-08 32.5 0.0 2.7e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Complex1_LYR PF05347.15 EGB12018.1 - 0.028 14.5 0.2 0.044 13.8 0.2 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) TPT PF03151.16 EGB12019.1 - 9.9e-11 41.5 1.4 0.00024 20.6 0.4 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EGB12019.1 - 0.18 12.0 13.1 0.076 13.2 3.8 2.6 2 1 0 2 2 2 0 EamA-like transporter family DUF3681 PF12442.8 EGB12019.1 - 2.4 8.7 7.8 0.38 11.2 3.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3681) Aldo_ket_red PF00248.21 EGB12020.1 - 7.2e-15 55.0 0.0 8e-13 48.2 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 EGB12020.1 - 5.6e-05 23.6 0.0 0.00024 21.6 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGB12020.1 - 0.00038 20.8 3.9 0.16 12.5 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB12020.1 - 0.0013 19.0 1.5 0.56 10.9 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EGB12020.1 - 0.0028 17.9 3.1 0.015 15.6 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FbpC_C_terminal PF17845.1 EGB12020.1 - 0.046 13.8 0.9 0.15 12.2 0.9 1.9 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain EF-hand_1 PF00036.32 EGB12021.1 - 0.00057 19.2 0.9 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB12021.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EGB12021.1 - 0.073 13.5 0.0 0.38 11.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair GrpE PF01025.19 EGB12022.1 - 3.8e-44 150.3 2.2 4.5e-44 150.0 2.2 1.0 1 0 0 1 1 1 1 GrpE Luciferase_3H PF10284.9 EGB12022.1 - 0.043 14.0 0.1 0.075 13.2 0.1 1.3 1 0 0 1 1 1 0 Luciferase helical bundle domain ApoLp-III PF07464.11 EGB12022.1 - 0.4 10.8 4.0 1 9.4 0.1 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Dak2 PF02734.17 EGB12022.1 - 0.48 10.3 6.4 3.6 7.4 2.7 2.3 1 1 1 2 2 2 0 DAK2 domain DUF883 PF05957.13 EGB12022.1 - 9.8 6.9 9.4 27 5.4 5.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) GTP_EFTU PF00009.27 EGB12023.1 - 2.8e-64 216.3 0.0 6e-64 215.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGB12023.1 - 1e-41 141.5 0.0 1.9e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGB12023.1 - 4.4e-33 113.2 0.0 8.6e-33 112.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGB12023.1 - 1.7e-26 92.1 0.0 5.3e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGB12023.1 - 1.4e-16 60.6 2.1 6.5e-15 55.3 0.2 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGB12023.1 - 6.4e-06 26.0 0.1 1.5e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGB12023.1 - 0.0027 17.8 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGB12023.1 - 0.034 13.5 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family peroxidase PF00141.23 EGB12024.1 - 2.7e-40 138.5 0.0 3.9e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase EAP30 PF04157.16 EGB12025.1 - 4.3e-52 176.7 0.0 4.9e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family XendoU PF09412.10 EGB12026.1 - 3.5e-44 151.0 0.0 3.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 EGB12026.1 - 0.061 13.7 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial EndoU nuclease Pkinase PF00069.25 EGB12027.1 - 1.1e-40 139.7 0.0 1.7e-36 126.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain HAD_SAK_2 PF18143.1 EGB12027.1 - 5e-28 98.2 0.1 2.3e-27 96.0 0.0 2.2 2 0 0 2 2 2 1 HAD domain in Swiss Army Knife RNA repair proteins Pkinase_Tyr PF07714.17 EGB12027.1 - 4.2e-14 52.4 0.0 1.2e-13 51.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_6 PF13405.6 EGB12027.1 - 1.4e-11 43.3 0.0 0.004 17.0 0.0 4.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGB12027.1 - 9.9e-11 40.4 0.3 0.0073 15.8 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGB12027.1 - 1.2e-10 41.7 0.0 1.9e-05 25.0 0.0 3.1 4 0 0 4 4 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB12027.1 - 2.9e-10 39.2 2.5 0.00044 19.6 0.0 3.9 5 0 0 5 5 5 2 EF hand XendoU PF09412.10 EGB12027.1 - 5.7e-07 29.0 0.0 8.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease XendoU RIO1 PF01163.22 EGB12027.1 - 9.4e-07 28.6 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family EF-hand_8 PF13833.6 EGB12027.1 - 0.00066 19.5 0.1 0.27 11.1 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair Kinase-like PF14531.6 EGB12027.1 - 0.026 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGB12027.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nudix_N_2 PF14803.6 EGB12027.1 - 0.22 11.5 1.6 15 5.6 0.1 3.3 4 0 0 4 4 3 0 Nudix N-terminal Kelch_4 PF13418.6 EGB12028.1 - 6.1e-19 67.8 4.8 1.1e-05 25.4 0.1 5.5 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGB12028.1 - 4.7e-13 48.9 0.1 0.26 11.6 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EGB12028.1 - 3.3e-12 46.1 0.2 2.1 8.4 0.0 6.7 6 0 0 6 6 6 4 Kelch motif FHA PF00498.26 EGB12028.1 - 9.6e-08 32.3 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain Kelch_1 PF01344.25 EGB12028.1 - 3.1e-07 29.9 2.6 0.033 13.8 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Yop-YscD_cpl PF16697.5 EGB12028.1 - 4.7e-07 30.0 0.0 9.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kelch_2 PF07646.15 EGB12028.1 - 0.00022 21.1 0.1 0.34 11.0 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 EGB12028.1 - 0.013 15.8 17.6 0.2 12.0 0.1 6.1 6 0 0 6 6 6 0 Galactose oxidase, central domain adh_short PF00106.25 EGB12028.1 - 0.068 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Fer2_4 PF13510.6 EGB12028.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.0 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain DUF1995 PF09353.10 EGB12029.1 - 1.3e-26 93.9 0.1 2.6e-26 92.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Radical_SAM PF04055.21 EGB12029.1 - 8.3e-23 81.6 0.0 2.4e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 Radical SAM superfamily A_deaminase PF00962.22 EGB12030.1 - 5.7e-108 361.1 0.2 2.2e-107 359.2 0.2 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase AA_kinase PF00696.28 EGB12031.1 - 8.7e-41 140.1 5.9 1.6e-40 139.2 5.9 1.5 1 0 0 1 1 1 1 Amino acid kinase family HMGL-like PF00682.19 EGB12031.1 - 7.5e-05 22.4 2.9 0.00021 21.0 2.9 1.7 1 0 0 1 1 1 1 HMGL-like EF-hand_1 PF00036.32 EGB12031.1 - 0.03 13.9 0.2 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EGB12031.1 - 0.031 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair U-box PF04564.15 EGB12032.1 - 5.7e-20 71.3 0.1 6.2e-20 71.1 0.1 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB12032.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGB12032.1 - 0.0032 17.5 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EGB12032.1 - 0.005 17.0 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 EGB12032.1 - 0.081 12.8 0.0 0.096 12.6 0.0 1.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3641 PF12345.8 EGB12033.1 - 5.3e-54 181.9 0.0 8.9e-54 181.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 EGB12033.1 - 3.1e-10 40.7 0.1 1.7e-09 38.3 0.0 2.1 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 EGB12033.1 - 0.0018 18.6 0.0 0.003 17.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Arm PF00514.23 EGB12034.1 - 1e-30 104.8 9.3 2.8e-08 33.5 0.0 5.2 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGB12034.1 - 9.3e-07 28.6 8.4 0.045 14.0 0.1 4.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EGB12034.1 - 2.6e-06 27.7 10.7 0.00015 22.0 4.1 3.0 1 1 2 3 3 3 3 HEAT repeats HEAT_EZ PF13513.6 EGB12034.1 - 1.3e-05 25.6 9.8 0.0016 18.9 1.4 4.1 2 2 3 5 5 5 2 HEAT-like repeat Arm_2 PF04826.13 EGB12034.1 - 1.8e-05 24.3 0.0 0.0011 18.4 0.0 2.7 1 1 0 1 1 1 1 Armadillo-like HEAT_PBS PF03130.16 EGB12034.1 - 0.0018 18.8 15.1 1.3 9.9 0.3 4.9 4 1 0 4 4 4 2 PBS lyase HEAT-like repeat PUL PF08324.11 EGB12034.1 - 0.011 15.0 0.4 0.022 14.0 0.2 1.6 1 1 0 1 1 1 0 PUL domain KAP PF05804.12 EGB12034.1 - 0.096 10.8 0.0 0.17 10.0 0.0 1.3 1 1 0 1 1 1 0 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EGB12034.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 V-ATPase subunit H Methyltransf_24 PF13578.6 EGB12035.1 - 5.7e-11 43.4 1.0 8e-11 42.9 0.2 1.7 2 0 0 2 2 2 1 Methyltransferase domain Chal_sti_synt_C PF02797.15 EGB12035.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain ADK PF00406.22 EGB12036.1 - 7e-54 182.0 0.0 8.7e-54 181.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGB12036.1 - 1.2e-26 93.8 0.0 2.5e-26 92.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EGB12036.1 - 5.8e-15 55.0 0.0 1.6e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGB12036.1 - 1.3e-06 29.0 0.0 2.8e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGB12036.1 - 8.8e-06 25.9 0.0 2.3e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EGB12036.1 - 1.6e-05 25.3 1.4 0.072 13.4 0.0 2.5 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 EGB12036.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_30 PF13604.6 EGB12036.1 - 0.05 13.3 1.3 0.45 10.2 0.3 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGB12036.1 - 0.075 12.9 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 EGB12036.1 - 0.095 13.1 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB12036.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EGB12036.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AdoHcyase PF05221.17 EGB12037.1 - 7.8e-143 475.0 0.0 8.8e-143 474.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGB12037.1 - 2.2e-74 248.9 4.1 3.1e-74 248.4 4.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGB12037.1 - 2.3e-06 27.1 0.5 3.8e-06 26.4 0.5 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGB12037.1 - 0.0028 17.0 1.6 0.0082 15.5 1.6 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IlvN PF07991.12 EGB12037.1 - 0.0092 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 EGB12037.1 - 0.012 15.7 0.3 0.038 14.1 0.3 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGB12037.1 - 0.015 15.8 0.1 0.033 14.6 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sel1 PF08238.12 EGB12038.1 - 5.4e-34 115.9 24.2 1.7e-08 34.9 0.2 8.2 8 0 0 8 8 8 5 Sel1 repeat TPR_12 PF13424.6 EGB12038.1 - 3e-06 27.4 12.0 0.98 9.8 0.4 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 EGB12038.1 - 0.0094 15.7 1.5 0.027 14.2 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EGB12038.1 - 0.0095 15.9 7.1 24 5.2 0.0 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat FumaraseC_C PF10415.9 EGB12038.1 - 0.038 14.4 3.4 6.7 7.2 0.0 3.9 4 0 0 4 4 4 0 Fumarase C C-terminus Phage_holin_6_1 PF09682.10 EGB12038.1 - 0.11 12.9 0.2 4.9 7.6 0.0 2.9 2 1 2 4 4 4 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF410 PF04190.13 EGB12038.1 - 0.17 11.7 1.0 9.5 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_3 PF07720.12 EGB12038.1 - 0.24 11.4 4.6 0.79 9.8 1.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 EGB12038.1 - 0.36 11.3 2.1 22 5.6 0.3 3.6 2 1 1 3 3 3 0 B12 binding domain TPR_10 PF13374.6 EGB12038.1 - 0.44 10.5 15.6 0.54 10.2 0.0 6.1 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB12038.1 - 1.3 9.8 0.0 1.3 9.8 0.0 4.8 8 0 0 8 8 8 0 Tetratricopeptide repeat Peptidase_C2 PF00648.21 EGB12039.1 - 3.6e-35 121.4 0.0 4.2e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease DUF4322 PF14210.6 EGB12039.1 - 0.038 13.9 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) AIRC PF00731.20 EGB12040.1 - 2.9e-64 215.1 2.5 3.9e-64 214.7 2.5 1.2 1 0 0 1 1 1 1 AIR carboxylase CLASP_N PF12348.8 EGB12041.1 - 5.1e-08 32.7 0.0 2.6e-06 27.2 0.0 2.3 1 1 2 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 EGB12041.1 - 5.2e-05 23.6 0.7 0.37 11.4 0.0 4.6 2 1 2 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EGB12041.1 - 0.0008 19.5 0.4 0.26 11.7 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EGB12041.1 - 0.0013 19.0 1.2 0.41 11.1 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats DUF3437 PF11919.8 EGB12041.1 - 0.0049 16.8 0.6 0.082 12.8 0.0 2.8 2 1 2 4 4 4 1 Domain of unknown function (DUF3437) Cnd1 PF12717.7 EGB12041.1 - 0.082 12.9 0.3 21 5.1 0.3 3.0 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 EGB12041.1 - 0.12 12.1 0.5 4.6 6.8 0.0 2.9 2 1 2 4 4 4 0 NUC173 domain MMS19_N PF14500.6 EGB12041.1 - 0.16 11.5 0.0 8.8 5.8 0.0 2.3 1 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Rit1_C PF17184.4 EGB12042.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Rit1 N-terminal domain Sm_multidrug_ex PF06695.11 EGB12043.1 - 5.7e-33 114.1 4.7 6.8e-33 113.9 4.7 1.1 1 0 0 1 1 1 1 Putative small multi-drug export protein Rad1 PF02144.16 EGB12044.1 - 2.4e-21 76.0 0.0 3.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PHD PF00628.29 EGB12044.1 - 0.00023 21.0 7.9 0.00052 19.9 7.9 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EGB12044.1 - 1.6 8.7 6.5 4.6 7.2 6.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PhyH PF05721.13 EGB12045.1 - 5.9e-13 49.6 0.1 7.4e-08 32.9 0.1 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) SURNod19 PF07712.12 EGB12046.1 - 8e-06 24.8 3.3 0.0024 16.7 0.2 3.1 3 0 0 3 3 3 2 Stress up-regulated Nod 19 Metallothi_Euk2 PF12809.7 EGB12046.1 - 6.5 7.1 9.4 0.24 11.7 2.6 2.0 2 0 0 2 2 2 0 Eukaryotic metallothionein Ribosomal_L5e PF17144.4 EGB12047.1 - 1.8e-78 262.1 1.9 1.8e-78 262.1 1.9 1.9 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGB12047.1 - 8.3e-31 106.8 5.0 8.3e-31 106.8 5.0 2.6 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region Pox_Ag35 PF03286.14 EGB12047.1 - 3.6 7.3 11.3 6.3 6.5 11.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 EGB12047.1 - 7 5.9 10.6 13 5.0 10.6 1.6 1 0 0 1 1 1 0 NOA36 protein MutS_V PF00488.21 EGB12048.1 - 1.3e-21 77.5 0.0 2.3e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V Smr PF01713.21 EGB12048.1 - 3.1e-11 43.5 2.6 1.2e-10 41.6 0.0 3.1 3 0 0 3 3 3 1 Smr domain AAA_21 PF13304.6 EGB12048.1 - 0.13 12.0 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system EGF PF00008.27 EGB12049.1 - 0.014 15.7 3.3 0.014 15.7 3.3 2.2 2 1 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 EGB12049.1 - 0.054 13.9 14.6 0.12 12.7 14.6 1.6 1 0 0 1 1 1 0 EGF-like domain SKA1 PF07160.12 EGB12049.1 - 1.1 9.1 2.6 0.46 10.3 0.1 1.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DSPc PF00782.20 EGB12050.1 - 3.1e-08 33.5 0.0 5.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGB12050.1 - 0.0006 20.0 0.0 0.0016 18.6 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGB12050.1 - 0.0015 18.1 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Na_H_antiport_1 PF06965.12 EGB12050.1 - 0.04 12.8 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Y_phosphatase3 PF13350.6 EGB12050.1 - 0.075 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Epimerase PF01370.21 EGB12051.1 - 4.5e-43 147.4 0.0 6.9e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB12051.1 - 9.9e-42 143.5 0.0 2.1e-41 142.4 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGB12051.1 - 1.2e-10 41.0 0.0 3.8e-09 36.1 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGB12051.1 - 1.5e-10 40.6 0.0 2.8e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGB12051.1 - 1.5e-10 40.7 0.3 3.7e-09 36.1 0.4 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 EGB12051.1 - 8.6e-06 25.8 0.2 2e-05 24.6 0.2 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EGB12051.1 - 0.00014 21.2 0.1 0.0013 18.0 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGB12051.1 - 0.0041 17.0 0.9 0.22 11.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding CAF1 PF04857.20 EGB12052.1 - 4.3e-17 62.3 0.5 2.6e-09 36.7 0.0 2.7 2 1 0 2 2 2 2 CAF1 family ribonuclease MORN PF02493.20 EGB12053.1 - 1.7e-16 59.0 39.2 0.00025 20.7 2.1 7.0 7 0 0 7 7 7 6 MORN repeat RmlD_sub_bind PF04321.17 EGB12054.1 - 2.5e-09 36.7 0.9 3.5e-08 32.9 0.8 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EGB12054.1 - 4.8e-06 26.3 0.1 2.2e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGB12054.1 - 0.00012 22.0 0.2 0.00024 21.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGB12054.1 - 0.0013 18.2 0.1 0.0036 16.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB12054.1 - 0.0072 15.4 0.0 0.067 12.2 0.1 2.2 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1471 PF07338.13 EGB12054.1 - 0.05 13.6 1.1 0.14 12.2 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) HSP70 PF00012.20 EGB12055.1 - 1.1e-110 370.6 6.1 3e-98 329.6 0.0 3.3 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EGB12055.1 - 1.6e-08 33.7 0.0 3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Aminotran_1_2 PF00155.21 EGB12056.1 - 6.7e-44 150.5 0.0 5.1e-43 147.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGB12056.1 - 0.00053 18.6 0.0 0.00081 18.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CS PF04969.16 EGB12057.1 - 5.7e-14 52.9 0.0 1.1e-10 42.4 0.0 2.4 2 0 0 2 2 2 2 CS domain Sigma70_ner PF04546.13 EGB12059.1 - 0.68 9.8 8.6 1 9.2 8.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TMEM169 PF15052.6 EGB12060.1 - 0.15 12.2 0.2 0.15 12.2 0.2 1.7 1 1 1 2 2 2 0 TMEM169 protein family TRP PF06011.12 EGB12060.1 - 1.4 7.6 7.2 8.5 5.0 7.3 1.8 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF3110 PF11360.8 EGB12061.1 - 1.2e-25 89.4 0.0 8e-24 83.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3110) UCH PF00443.29 EGB12061.1 - 5.4e-14 52.3 0.0 1.6e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB12061.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Epimerase PF01370.21 EGB12062.1 - 1.6e-18 67.1 0.0 2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB12062.1 - 5.3e-13 49.1 0.0 8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGB12062.1 - 2e-12 46.8 0.0 1.1e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EGB12062.1 - 5.5e-12 45.3 0.0 8.6e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGB12062.1 - 5e-06 25.8 0.0 2.8e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGB12062.1 - 2.2e-05 23.7 0.0 0.00058 19.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EGB12062.1 - 0.0011 18.5 0.2 0.0038 16.7 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB12062.1 - 0.0011 18.9 0.6 0.0038 17.2 0.6 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EGB12063.1 - 2.4e-34 118.5 0.0 3.4e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB12063.1 - 4.3e-25 88.6 0.1 5.8e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB12063.1 - 8.8e-11 42.0 0.0 1.5e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB12063.1 - 1.6e-07 31.1 0.1 2.7e-07 30.3 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ion_trans PF00520.31 EGB12064.1 - 6.2e-08 32.2 13.4 1.1e-07 31.4 13.4 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB12064.1 - 1.3e-06 28.4 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Osw5 PF17062.5 EGB12064.1 - 0.021 14.9 0.0 0.085 13.0 0.0 2.0 1 0 0 1 1 1 0 Outer spore wall 5 DUF5305 PF17231.2 EGB12064.1 - 0.15 11.5 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) GATase PF00117.28 EGB12064.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Ion_trans PF00520.31 EGB12065.1 - 2.1e-32 112.3 0.0 2.4e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 EGB12066.1 - 8.2e-40 136.6 3.5 3.6e-22 78.8 1.8 2.0 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 EGB12066.1 - 0.024 13.4 2.0 0.41 9.3 0.4 2.2 2 0 0 2 2 2 0 Polycystin cation channel Shisa PF13908.6 EGB12066.1 - 0.21 11.8 0.1 0.34 11.1 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ion_trans PF00520.31 EGB12067.1 - 4e-19 68.8 2.6 4.1e-19 68.8 2.6 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGB12067.1 - 1.5e-05 23.9 0.6 1.7e-05 23.7 0.6 1.0 1 0 0 1 1 1 1 Polycystin cation channel NADH_4Fe-4S PF10589.9 EGB12068.1 - 0.029 14.5 0.7 0.56 10.3 0.0 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region TPR_2 PF07719.17 EGB12068.1 - 2.1 8.6 9.0 39 4.7 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat KIAA1430 PF13879.6 EGB12069.1 - 1.7e-14 54.4 0.8 4.9e-14 52.9 0.8 1.8 1 0 0 1 1 1 1 KIAA1430 homologue Band_7 PF01145.25 EGB12069.1 - 3.1e-10 40.3 0.5 3.1e-10 40.3 0.5 3.0 3 1 0 3 3 3 1 SPFH domain / Band 7 family YHYH PF14240.6 EGB12070.1 - 7.3e-07 29.3 0.0 2.7e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 YHYH protein DUF4795 PF16043.5 EGB12071.1 - 0.001 18.7 1.0 0.001 18.7 1.0 3.3 3 2 0 3 3 3 1 Domain of unknown function (DUF4795) HrpB7 PF09486.10 EGB12071.1 - 0.018 15.4 2.5 0.018 15.4 2.5 3.8 4 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) RRM_1 PF00076.22 EGB12071.1 - 0.025 14.4 0.0 2.1 8.2 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lebercilin PF15619.6 EGB12071.1 - 0.15 11.7 0.1 0.15 11.7 0.1 3.3 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease T3SS_needle_F PF09392.10 EGB12071.1 - 0.17 12.1 0.8 27 5.0 0.1 2.9 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF EccE PF11203.8 EGB12071.1 - 0.27 11.6 2.9 12 6.3 0.0 4.6 3 1 0 5 5 5 0 Putative type VII ESX secretion system translocon, EccE Baculo_PEP_C PF04513.12 EGB12071.1 - 0.34 10.9 5.0 0.91 9.6 0.2 3.3 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_topoisoIV PF00521.20 EGB12071.1 - 0.51 9.2 2.6 0.84 8.5 0.0 2.1 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A Snapin_Pallidin PF14712.6 EGB12071.1 - 4.4 7.8 6.2 17 5.9 1.0 4.2 5 1 0 5 5 5 0 Snapin/Pallidin UQ_con PF00179.26 EGB12072.1 - 4e-37 127.0 0.0 5e-37 126.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGB12072.1 - 0.0002 21.1 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGB12072.1 - 0.00091 19.5 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain ANAPC4_WD40 PF12894.7 EGB12073.1 - 1.4e-11 44.5 0.6 0.0035 17.6 0.3 5.6 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGB12073.1 - 3.8e-10 40.2 7.5 1.8e-05 25.4 0.1 7.0 8 0 0 8 8 8 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGB12073.1 - 2.6e-05 23.5 15.1 0.5 9.3 0.4 5.4 3 2 2 5 5 5 4 Coatomer WD associated region Clathrin PF00637.20 EGB12073.1 - 7.2e-05 22.7 9.4 0.54 10.1 0.1 4.6 3 1 2 5 5 5 3 Region in Clathrin and VPS Nudix_N_2 PF14803.6 EGB12073.1 - 0.0094 15.8 2.7 0.038 13.9 2.7 2.0 1 1 0 1 1 1 1 Nudix N-terminal DUF2829 PF11195.8 EGB12073.1 - 0.07 13.4 0.4 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) PHTB1_N PF14727.6 EGB12073.1 - 0.14 11.5 0.0 0.82 9.0 0.0 2.2 3 0 0 3 3 3 0 PTHB1 N-terminus TauE PF01925.19 EGB12074.1 - 0.00093 18.9 0.0 0.00093 18.9 0.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Tmemb_14 PF03647.13 EGB12074.1 - 0.035 14.8 0.2 0.061 14.1 0.2 1.3 1 0 0 1 1 1 0 Transmembrane proteins 14C Synaptobrevin PF00957.21 EGB12075.1 - 3.7e-30 103.6 1.7 5e-30 103.1 1.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGB12075.1 - 5.8e-24 83.9 0.1 9.4e-24 83.3 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ferlin_C PF16165.5 EGB12075.1 - 0.018 15.0 0.2 0.031 14.2 0.2 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Cyclin_N PF00134.23 EGB12076.1 - 2.2e-10 40.3 0.2 2.7e-10 40.1 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGB12076.1 - 4.8e-09 36.8 0.1 5.5e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin UPF0176_N PF17773.1 EGB12077.1 - 1.1e-11 44.9 0.0 2.8e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 EGB12077.1 - 1.2e-11 44.8 5.5 2.3e-11 43.9 5.5 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 EGB12077.1 - 0.031 14.8 0.0 0.1 13.1 0.0 2.0 1 0 0 1 1 1 0 Rhodanese-like domain Snapin_Pallidin PF14712.6 EGB12077.1 - 0.32 11.4 8.4 0.059 13.8 0.5 3.3 3 0 0 3 3 3 0 Snapin/Pallidin FlgM PF04316.13 EGB12077.1 - 1.5 9.2 5.8 0.43 11.0 0.8 2.9 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Trehalose_PPase PF02358.16 EGB12078.1 - 4.6e-44 150.3 0.0 5.9e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGB12078.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2019 PF09450.10 EGB12078.1 - 0.063 13.2 0.2 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Glycos_transf_1 PF00534.20 EGB12079.1 - 8.3e-07 28.7 0.0 2.6e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGB12079.1 - 8.3e-06 25.9 0.1 5.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGB12079.1 - 0.0012 19.3 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 CTP_transf_like PF01467.26 EGB12080.1 - 1.8e-05 25.0 0.0 9.8e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Cytidylyltransferase-like Ribosomal_L32e PF01655.18 EGB12081.1 - 1e-49 167.5 2.2 1.2e-49 167.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 MoeA_N PF03453.17 EGB12082.1 - 3.5e-29 101.6 1.1 7.7e-29 100.5 1.1 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EGB12082.1 - 3.6e-20 72.1 0.0 6.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EGB12082.1 - 1.8e-09 37.6 0.3 3.7e-08 33.4 0.3 2.6 1 1 0 1 1 1 1 MoeA C-terminal region (domain IV) NAD_binding_10 PF13460.6 EGB12082.1 - 0.0081 16.1 2.6 0.016 15.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Glyco_hydro_16 PF00722.21 EGB12083.1 - 3.3e-10 39.7 0.0 6.2e-09 35.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF5110 PF17137.4 EGB12083.1 - 0.0091 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) SANT_DAMP1_like PF16282.5 EGB12084.1 - 0.085 13.1 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Peptidase_M24 PF00557.24 EGB12085.1 - 6.3e-43 146.9 0.0 1.1e-42 146.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EGB12085.1 - 3.8e-42 144.1 0.0 5.6e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGB12085.1 - 1.6e-22 79.3 0.0 3.5e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EGB12085.1 - 1.5e-17 64.4 0.0 6.1e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ATP-grasp_4 PF13535.6 EGB12086.1 - 5.2e-08 32.6 0.0 1.4e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGB12086.1 - 0.00047 20.3 0.0 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EGB12086.1 - 0.0071 16.1 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 EGB12086.1 - 0.046 13.5 0.0 0.25 11.1 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon AhpC-TSA PF00578.21 EGB12087.1 - 8.5e-23 80.6 0.0 1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGB12087.1 - 6.1e-14 52.0 0.0 7.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin CT_C_D PF02682.16 EGB12088.1 - 3.3e-63 213.1 0.4 3.7e-63 212.9 0.4 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Thioredoxin_8 PF13905.6 EGB12089.1 - 1.2e-26 92.9 0.0 1.3e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EGB12089.1 - 4.4e-09 36.3 0.0 4.4e-05 23.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGB12089.1 - 1.8e-08 34.8 0.0 2.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EGB12089.1 - 8e-07 28.9 0.0 9.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGB12089.1 - 2.2e-06 27.6 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EGB12089.1 - 0.003 17.7 0.0 0.027 14.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EGB12089.1 - 0.034 13.9 0.0 2.6 7.8 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin HyaE PF07449.11 EGB12089.1 - 0.16 12.0 0.0 0.72 9.8 0.0 1.8 1 1 1 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 EGB12089.1 - 0.18 11.6 0.0 0.6 9.9 0.0 1.7 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 EGB12089.1 - 0.19 11.9 0.0 2.5 8.2 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Glyco_hydro_3 PF00933.21 EGB12090.1 - 1.9e-54 185.2 0.0 2.5e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EGB12090.1 - 3.5e-39 134.9 0.1 5.7e-39 134.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EGB12090.1 - 4.9e-22 77.8 0.2 8.9e-22 77.0 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MMADHC PF10229.9 EGB12091.1 - 1.4e-22 80.8 0.1 2.1e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein FAD_binding_3 PF01494.19 EGB12091.1 - 3.3e-12 46.3 11.3 2.1e-08 33.8 1.0 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EGB12091.1 - 8.6e-06 25.9 0.1 2.9e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB12091.1 - 4.2e-05 23.3 3.8 0.00054 19.6 1.4 2.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGB12091.1 - 0.00028 20.2 0.4 0.00045 19.5 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGB12091.1 - 0.0026 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EGB12091.1 - 0.0028 18.2 0.2 0.0053 17.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGB12091.1 - 0.017 14.3 0.4 0.032 13.3 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EGB12091.1 - 0.022 14.0 0.3 0.038 13.2 0.3 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EGB12091.1 - 0.035 13.4 0.3 0.059 12.7 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EGB12091.1 - 0.062 12.0 0.1 0.091 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EGB12091.1 - 0.36 9.9 1.1 0.56 9.2 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribosomal_L24e PF01246.20 EGB12093.1 - 6.6e-32 109.6 3.6 6.6e-32 109.6 3.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4510 PF14971.6 EGB12093.1 - 0.03 14.7 1.1 0.036 14.4 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) CHASE8 PF17152.4 EGB12093.1 - 0.069 13.4 2.0 0.28 11.5 1.4 2.0 2 0 0 2 2 2 0 Periplasmic sensor domain SHS2_Rpb7-N PF03876.17 EGB12094.1 - 5.2e-09 36.4 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EGB12094.1 - 7.6e-08 32.6 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Glycos_transf_2 PF00535.26 EGB12095.1 - 0.21 11.4 1.4 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sulfotransfer_2 PF03567.14 EGB12096.1 - 0.0031 17.5 0.1 0.065 13.1 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family WW PF00397.26 EGB12097.1 - 9e-12 44.9 1.7 1.7e-11 44.0 1.7 1.5 1 0 0 1 1 1 1 WW domain Methyltransf_25 PF13649.6 EGB12098.1 - 4.5e-06 27.3 0.2 1.5e-05 25.6 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 EGB12098.1 - 0.0003 20.0 0.0 0.00044 19.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 EGB12098.1 - 0.00035 21.1 0.1 0.0038 17.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB12098.1 - 0.0097 16.6 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB12098.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LRRNT PF01462.18 EGB12098.1 - 1.5 8.5 3.9 5.9 6.7 0.2 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain ABC2_membrane PF01061.24 EGB12099.1 - 5e-43 147.0 31.7 6.1e-27 94.4 14.5 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGB12099.1 - 1.8e-27 96.6 0.0 1.3e-12 48.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EGB12099.1 - 1.6e-09 37.9 0.1 0.00015 21.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EGB12099.1 - 0.00013 21.8 2.0 0.11 12.2 0.3 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGB12099.1 - 0.00013 22.0 1.0 0.05 13.7 0.2 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB12099.1 - 0.00032 21.1 1.0 0.18 12.2 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain NACHT PF05729.12 EGB12099.1 - 0.00035 20.5 1.1 0.081 12.8 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_29 PF13555.6 EGB12099.1 - 0.00057 19.6 3.7 0.31 10.8 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EGB12099.1 - 0.00085 18.9 3.7 0.099 12.2 0.2 3.2 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EGB12099.1 - 0.0017 18.6 0.9 1.9 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGB12099.1 - 0.0048 17.2 1.0 0.59 10.5 0.1 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 EGB12099.1 - 0.0063 16.4 0.5 0.58 10.0 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 EGB12099.1 - 0.0069 16.8 0.3 1.5 9.2 0.1 2.4 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EGB12099.1 - 0.019 15.2 3.2 1.5 9.1 0.4 2.6 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EGB12099.1 - 0.042 13.4 0.1 6 6.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF463 PF04317.12 EGB12099.1 - 0.048 12.6 0.1 3.2 6.6 0.0 2.1 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_24 PF13479.6 EGB12099.1 - 0.076 12.7 1.3 11 5.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EGB12099.1 - 0.11 12.6 0.6 4.2 7.4 0.1 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 EGB12099.1 - 0.12 11.7 3.1 1.7 7.9 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC2_membrane_3 PF12698.7 EGB12099.1 - 0.12 11.4 24.4 0.47 9.5 11.2 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein Roc PF08477.13 EGB12099.1 - 0.25 11.5 0.2 24 5.1 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EGB12099.1 - 0.27 10.8 2.9 8 6.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGB12099.1 - 0.28 10.5 1.7 8.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 EGB12099.1 - 0.28 10.2 1.7 17 4.4 0.3 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 EGB12099.1 - 0.36 11.3 5.4 1.4 9.3 0.6 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EGB12099.1 - 0.68 9.2 1.1 4 6.6 0.1 2.0 2 0 0 2 2 2 0 Septin PRK PF00485.18 EGB12099.1 - 0.72 9.6 2.3 15 5.2 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 EGB12099.1 - 0.96 8.9 2.9 4.7 6.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.23 EGB12099.1 - 1 9.4 2.8 1.2 9.1 0.8 1.9 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EGB12099.1 - 2.3 8.3 6.9 9.1 6.3 1.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain TPR_12 PF13424.6 EGB12100.1 - 1.7e-77 255.7 48.7 4.8e-18 65.2 3.6 5.8 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 EGB12100.1 - 3.3e-52 173.0 30.0 1.6e-10 40.5 0.2 6.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGB12100.1 - 7.7e-29 97.6 22.4 8.7e-07 28.5 0.2 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGB12100.1 - 1.7e-26 90.2 13.3 7e-05 22.7 0.1 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12100.1 - 6.5e-24 82.7 14.7 2.1e-06 27.3 0.1 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGB12100.1 - 2.1e-20 71.1 20.5 4.4e-06 26.4 0.1 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_4 PF07721.14 EGB12100.1 - 1.9e-11 43.4 3.7 2.9 8.8 0.0 5.8 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGB12100.1 - 3.9e-10 39.7 14.4 0.23 12.4 0.1 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGB12100.1 - 3.4e-09 36.8 10.3 0.18 12.5 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_5 PF12688.7 EGB12100.1 - 2.2e-08 34.4 9.4 0.00063 20.0 0.2 4.8 1 1 4 5 5 5 2 Tetratrico peptide repeat TPR_17 PF13431.6 EGB12100.1 - 7.2e-08 32.3 6.2 4.7 7.8 0.0 6.2 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB12100.1 - 1.2e-07 32.3 22.7 0.00028 21.5 4.1 4.3 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGB12100.1 - 1e-05 25.1 14.9 0.14 11.9 0.6 5.4 5 0 0 5 5 5 2 TPR repeat Mob_Pre PF01076.19 EGB12100.1 - 7.9e-05 22.6 1.0 11 5.8 0.0 4.6 3 2 2 5 5 5 0 Plasmid recombination enzyme TAtT PF16811.5 EGB12100.1 - 0.00016 21.0 3.2 0.024 13.9 0.3 2.6 1 1 1 2 2 2 2 TRAP transporter T-component Pox_H7 PF04787.12 EGB12100.1 - 0.00039 21.0 0.0 2.6 8.5 0.0 3.0 2 1 1 3 3 3 1 Late protein H7 Fis1_TPR_C PF14853.6 EGB12100.1 - 0.0018 18.3 10.5 1.2 9.3 0.1 4.8 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat DUF4807 PF16065.5 EGB12100.1 - 0.0043 16.7 1.4 23 4.7 0.1 4.6 3 2 1 5 5 5 0 Domain of unknown function (DUF4807) SPO22 PF08631.10 EGB12100.1 - 0.16 11.4 0.3 49 3.3 0.1 3.2 1 1 2 4 4 4 0 Meiosis protein SPO22/ZIP4 like DUF627 PF04781.12 EGB12100.1 - 0.18 11.8 1.2 18 5.4 0.0 3.6 3 2 1 5 5 5 0 Protein of unknown function (DUF627) DUF3583 PF12126.8 EGB12100.1 - 1.7 8.1 5.9 28 4.0 0.2 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF3583) CbtA PF09490.10 EGB12101.1 - 0.0012 18.7 0.6 0.0016 18.3 0.6 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) ETRAMP PF09716.10 EGB12101.1 - 0.073 13.1 0.2 0.079 13.0 0.2 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ISG65-75 PF11727.8 EGB12101.1 - 1.3 8.2 4.8 1.7 7.8 4.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein TAL_FSA PF00923.19 EGB12102.1 - 1.9e-18 66.8 0.0 4.5e-16 59.1 0.0 2.1 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 EGB12103.1 - 3.4e-44 151.2 0.0 3.9e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12103.1 - 7e-26 91.1 0.0 8.6e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB12103.1 - 7.3e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGB12103.1 - 8.3e-05 22.6 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGB12103.1 - 0.0024 17.2 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB12103.1 - 0.062 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGB12103.1 - 0.081 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Defensin_beta_2 PF13841.6 EGB12103.1 - 0.72 10.4 3.8 0.83 10.2 0.1 2.1 2 0 0 2 2 2 0 Beta defensin EMC3_TMCO1 PF01956.16 EGB12104.1 - 8.5e-48 162.3 0.6 1.3e-47 161.7 0.6 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like CDP-OH_P_transf PF01066.21 EGB12105.1 - 1.1e-11 45.3 0.1 1.5e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase LSM PF01423.22 EGB12106.1 - 2.4e-17 62.3 0.2 3.2e-17 62.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.8 EGB12106.1 - 0.52 10.9 5.3 0.31 11.6 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) MORN PF02493.20 EGB12107.1 - 2.2e-16 58.7 25.7 2.3e-07 30.3 0.3 5.1 6 0 0 6 6 6 3 MORN repeat Ion_trans PF00520.31 EGB12108.1 - 5.2e-15 55.4 2.7 8.1e-15 54.7 2.7 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB12108.1 - 3e-13 49.7 0.0 6.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGB12108.1 - 2.5e-12 46.6 1.8 5.6e-12 45.5 1.8 1.6 1 0 0 1 1 1 1 Ion channel Nucleotid_trans PF03407.16 EGB12108.1 - 0.00019 21.5 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase VCBS PF13517.6 EGB12109.1 - 2.2e-19 69.8 66.6 3.9e-09 37.0 9.0 8.2 4 2 5 9 9 9 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB12109.1 - 1.6e-05 24.9 72.1 0.011 15.8 1.9 9.8 9 0 0 9 9 9 5 FG-GAP repeat PQQ_3 PF13570.6 EGB12109.1 - 8.9 6.9 21.2 0.15 12.6 1.1 5.7 4 0 0 4 4 4 0 PQQ-like domain Band_7 PF01145.25 EGB12110.1 - 1.3e-15 57.9 0.1 1.3e-15 57.9 0.1 3.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 EGB12110.1 - 4e-07 30.2 9.5 4e-07 30.2 9.5 4.4 2 1 2 4 4 4 1 Flotillin BCOR PF15808.5 EGB12110.1 - 4.9 7.3 7.9 5.9 7.1 6.9 1.5 1 1 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region Ammonium_transp PF00909.21 EGB12111.1 - 1.8e-115 385.9 33.7 2e-115 385.7 33.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3188 PF11384.8 EGB12111.1 - 0.0065 16.2 0.1 0.026 14.2 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) Malic_M PF03949.15 EGB12112.1 - 3.8e-88 295.1 0.3 5.7e-88 294.5 0.3 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGB12112.1 - 1.9e-71 239.6 0.0 3e-71 239.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Skp1 PF01466.19 EGB12114.1 - 6.6e-29 99.8 0.4 6.6e-29 99.8 0.4 2.3 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGB12114.1 - 4.8e-17 61.9 0.3 9.3e-17 61.0 0.3 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGB12114.1 - 0.0019 18.4 0.8 0.077 13.2 0.1 2.1 1 1 1 2 2 2 2 BTB/POZ domain Herpes_U59 PF04529.12 EGB12114.1 - 0.0097 15.0 0.6 1.2 8.1 0.1 2.1 2 0 0 2 2 2 2 Herpesvirus U59 protein PP2C PF00481.21 EGB12115.1 - 9.6e-29 100.8 0.4 1.1e-28 100.6 0.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB12115.1 - 0.00013 21.7 0.1 0.00019 21.2 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C HSF_DNA-bind PF00447.17 EGB12116.1 - 6e-19 68.5 0.0 9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding MtN3_slv PF03083.16 EGB12117.1 - 7.6e-31 106.0 0.1 9.9e-18 64.0 0.0 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Thioesterase PF00975.20 EGB12118.1 - 1.8e-23 83.9 0.0 2.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGB12118.1 - 1.3e-06 29.2 4.3 1.9e-06 28.6 4.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EGB12118.1 - 0.0042 16.7 0.0 0.006 16.2 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGB12118.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EGB12118.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.13 EGB12118.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) SelR PF01641.18 EGB12119.1 - 2.5e-24 85.7 2.2 3e-24 85.4 2.2 1.1 1 0 0 1 1 1 1 SelR domain Ribosomal_L27e PF01777.18 EGB12120.1 - 5.9e-25 87.4 4.2 7.8e-25 87.0 4.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGB12120.1 - 1.5e-05 24.8 0.9 1.5e-05 24.8 0.9 2.1 2 1 0 2 2 2 1 KOW motif Band_7 PF01145.25 EGB12121.1 - 2.5e-19 69.9 0.8 4.2e-19 69.2 0.5 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family DUF4246 PF14033.6 EGB12122.1 - 1.8e-61 208.7 0.0 2e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EGB12122.1 - 0.0045 17.4 0.0 0.0083 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Ribosomal_S15 PF00312.22 EGB12123.1 - 1e-25 89.7 0.2 1.5e-25 89.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Thr_synth_N PF14821.6 EGB12124.1 - 1.9e-26 92.1 0.0 1.2e-25 89.5 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EGB12124.1 - 2e-18 66.9 4.9 3.2e-18 66.2 4.9 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sulfotransfer_2 PF03567.14 EGB12125.1 - 0.00075 19.5 0.1 0.042 13.7 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase family Arm PF00514.23 EGB12126.1 - 6.5e-28 95.9 16.3 2.9e-08 33.4 0.2 6.0 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB12126.1 - 2.6e-08 34.1 18.1 1.8e-05 25.0 6.3 3.1 1 1 2 3 3 3 3 HEAT repeats HEAT_EZ PF13513.6 EGB12126.1 - 2.1e-06 28.1 18.3 0.12 12.9 0.5 5.0 4 1 1 5 5 5 4 HEAT-like repeat HEAT PF02985.22 EGB12126.1 - 5.5e-05 23.1 13.8 0.13 12.5 0.2 5.0 5 1 1 6 6 6 3 HEAT repeat Arm_2 PF04826.13 EGB12126.1 - 0.0014 18.2 0.0 1.7 8.1 0.0 2.6 1 1 2 3 3 3 2 Armadillo-like DUF3572 PF12096.8 EGB12126.1 - 0.011 15.9 8.8 0.29 11.3 1.3 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3572) Cnd1 PF12717.7 EGB12126.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Aconitase_B_N PF11791.8 EGB12126.1 - 0.027 14.6 0.6 12 5.9 0.0 3.3 1 1 2 3 3 3 0 Aconitate B N-terminal domain DUF3535 PF12054.8 EGB12126.1 - 0.035 13.4 0.0 0.083 12.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3535) Lipase_GDSL_2 PF13472.6 EGB12127.1 - 2.3e-18 67.2 1.3 2.3e-18 67.2 1.3 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGB12127.1 - 6.1e-06 26.3 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Herpes_LMP1 PF05297.11 EGB12127.1 - 3.1 6.9 41.0 0.033 13.4 27.3 2.2 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Kunitz_BPTI PF00014.23 EGB12127.1 - 6.6 7.1 22.4 2.8 8.3 5.3 3.7 3 0 0 3 3 3 0 Kunitz/Bovine pancreatic trypsin inhibitor domain PRK PF00485.18 EGB12128.1 - 1.6e-44 152.0 0.0 2e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 EGB12128.1 - 1.1e-05 25.8 0.1 0.0014 19.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGB12128.1 - 6e-05 23.2 0.0 8.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGB12128.1 - 9.2e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EGB12128.1 - 0.00011 22.7 0.1 0.00046 20.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EGB12128.1 - 0.0015 18.3 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 2 Dephospho-CoA kinase Cytidylate_kin PF02224.18 EGB12128.1 - 0.0024 17.6 0.1 0.22 11.2 0.1 2.1 2 0 0 2 2 2 1 Cytidylate kinase T2SSE PF00437.20 EGB12128.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.12 EGB12128.1 - 0.034 14.0 0.1 0.64 9.8 0.0 2.1 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.14 EGB12128.1 - 0.099 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Cullin_Nedd8 PF10557.9 EGB12129.1 - 4.9e-22 77.7 0.0 5.6e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Cullin protein neddylation domain TPR_17 PF13431.6 EGB12129.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3658 PF12395.8 EGB12129.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function Abhydrolase_1 PF00561.20 EGB12130.1 - 3e-13 50.0 0.3 6.4e-13 48.9 0.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB12130.1 - 2.9e-08 33.3 0.2 7.4e-08 31.9 0.2 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGB12130.1 - 5.8e-08 33.6 43.7 5.8e-08 33.6 43.7 3.8 2 2 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGB12130.1 - 0.0016 18.3 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EGB12130.1 - 0.0042 17.2 0.1 0.012 15.7 0.1 1.7 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EGB12130.1 - 0.012 15.2 0.2 0.021 14.5 0.2 1.3 1 0 0 1 1 1 0 Putative esterase RHH_5 PF07878.11 EGB12130.1 - 0.052 13.4 0.3 4.8 7.1 0.1 2.8 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 AXE1 PF05448.12 EGB12130.1 - 0.32 9.6 0.2 0.51 9.0 0.2 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) EF-hand_1 PF00036.32 EGB12131.1 - 2.5e-14 51.7 0.0 0.0001 21.6 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB12131.1 - 8e-13 47.2 0.4 0.00035 20.3 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EGB12131.1 - 1.2e-12 48.1 0.5 1.5e-07 31.8 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB12131.1 - 1e-07 31.1 1.2 0.055 13.0 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGB12131.1 - 2.7e-05 23.9 0.2 0.15 11.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair DUF1840 PF08895.11 EGB12131.1 - 0.021 15.1 0.2 3.3 8.1 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) TPR_2 PF07719.17 EGB12133.1 - 9.9e-11 40.9 15.8 0.00045 20.1 2.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12133.1 - 9.2e-09 34.8 11.4 0.0032 17.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB12133.1 - 0.00035 21.0 10.4 0.0004 20.8 2.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB12133.1 - 0.001 19.3 13.7 0.19 12.1 5.4 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGB12133.1 - 0.0011 19.1 5.8 0.0011 19.1 5.8 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB12133.1 - 0.0033 18.1 16.9 0.17 12.8 0.8 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF2786 PF10979.8 EGB12133.1 - 0.015 15.2 2.6 0.039 13.9 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) TPR_8 PF13181.6 EGB12133.1 - 0.026 14.7 5.6 0.063 13.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB12133.1 - 0.25 12.0 28.3 0.14 12.8 3.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB12133.1 - 3.6 7.4 8.4 1.5 8.6 1.1 2.7 2 1 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 EGB12133.1 - 7.5 7.4 8.4 14 6.6 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB12133.1 - 8.9 6.3 18.2 5.4 7.0 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1800 PF08811.11 EGB12134.1 - 1.6e-45 156.0 0.0 1.8e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) Myotub-related PF06602.14 EGB12137.1 - 5.9e-98 328.0 0.0 6.8e-98 327.8 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 EGB12137.1 - 0.00093 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGB12137.1 - 0.0014 18.6 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGB12137.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Chloroa_b-bind PF00504.21 EGB12138.1 - 1.4e-27 97.2 0.0 1.7e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein WD40 PF00400.32 EGB12139.1 - 7.5e-15 55.1 7.5 0.0051 17.6 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGB12139.1 - 0.028 13.2 0.0 0.057 12.2 0.0 1.5 1 1 1 2 2 2 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EGB12139.1 - 0.048 14.0 0.0 0.48 10.8 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Acyltransferase PF01553.21 EGB12140.1 - 1.3e-05 24.8 0.0 0.0053 16.4 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase Glyco_hydro_16 PF00722.21 EGB12141.1 - 1.5e-30 106.0 0.0 1.9e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGB12141.1 - 1.2e-08 33.8 0.0 0.00044 18.8 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) NDUF_B7 PF05676.13 EGB12143.1 - 8.2e-27 92.7 3.7 8.8e-27 92.6 3.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGB12143.1 - 0.016 15.2 0.5 0.02 14.9 0.5 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pkinase PF00069.25 EGB12144.1 - 1.4e-61 208.2 0.0 1.7e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12144.1 - 9e-34 116.9 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB12144.1 - 1.1e-06 28.1 0.1 1.9e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB12144.1 - 9.9e-05 21.3 0.0 0.00022 20.1 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB12144.1 - 0.00024 21.1 0.1 0.00052 20.0 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGB12144.1 - 0.0062 16.1 0.4 0.06 12.9 0.1 2.0 1 1 1 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EGB12144.1 - 0.06 12.9 0.2 0.13 11.8 0.2 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF4719 PF15843.5 EGB12144.1 - 0.11 12.5 0.9 0.17 12.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Kinase-like PF14531.6 EGB12144.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Peptidase_S8 PF00082.22 EGB12145.1 - 1.1e-14 54.4 10.1 4.2e-14 52.5 10.1 1.9 1 1 0 1 1 1 1 Subtilase family Abhydro_lipase PF04083.16 EGB12146.1 - 1.7e-14 53.1 0.0 2.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGB12146.1 - 0.0037 16.9 0.1 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB12146.1 - 0.066 12.5 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Macro PF01661.21 EGB12147.1 - 4.8e-18 65.3 0.0 8.9e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain PARP PF00644.20 EGB12147.1 - 2.1e-07 30.8 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain LRR_8 PF13855.6 EGB12148.1 - 2e-30 104.3 28.2 2e-12 46.6 3.5 4.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGB12148.1 - 4.7e-15 55.4 15.0 0.00015 22.1 0.9 4.0 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGB12148.1 - 0.00029 20.4 0.1 0.02 14.4 0.1 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 EGB12148.1 - 0.00068 19.6 0.0 0.09 12.7 0.0 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DASH_Dam1 PF08653.10 EGB12148.1 - 0.0017 18.1 6.9 4.1 7.3 0.1 4.9 2 1 3 5 5 5 1 DASH complex subunit Dam1 Cys_Met_Meta_PP PF01053.20 EGB12148.1 - 0.048 12.2 0.7 13 4.1 0.0 3.5 1 1 3 5 5 5 0 Cys/Met metabolism PLP-dependent enzyme DUF5602 PF18197.1 EGB12148.1 - 0.39 11.2 1.6 61 4.2 0.0 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF5602) LRR_1 PF00560.33 EGB12148.1 - 0.65 10.8 15.1 14 6.7 0.4 6.0 4 2 1 5 5 5 0 Leucine Rich Repeat VCBS PF13517.6 EGB12149.1 - 8.2e-35 119.2 60.5 8.9e-11 42.2 4.8 7.9 5 2 3 8 8 8 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB12149.1 - 4.8e-21 74.6 99.4 0.0016 18.5 5.4 11.0 10 0 0 10 10 10 10 FG-GAP repeat Laminin_EGF PF00053.24 EGB12149.1 - 0.00077 19.5 9.3 0.00077 19.5 9.3 4.6 5 1 0 5 5 5 2 Laminin EGF domain BBS2_Mid PF14783.6 EGB12149.1 - 0.0042 17.1 1.6 69 3.5 0.0 5.8 7 0 0 7 7 7 0 Ciliary BBSome complex subunit 2, middle region MgtC PF02308.16 EGB12149.1 - 2.2 8.6 6.5 1.1 9.7 3.0 2.1 2 0 0 2 2 2 0 MgtC family DBI_PRT PF02277.17 EGB12150.1 - 1e-93 314.2 30.8 1.3e-93 313.9 30.8 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase Hist_deacetyl PF00850.19 EGB12151.1 - 1.1e-75 255.0 0.0 1.3e-75 254.7 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Lipase_GDSL_2 PF13472.6 EGB12151.1 - 0.016 15.6 0.5 0.061 13.7 0.0 2.0 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family 2OG-FeII_Oxy_3 PF13640.6 EGB12152.1 - 9.3e-13 48.9 0.0 1.5e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB12152.1 - 0.0013 19.2 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 EGB12153.1 - 6.4e-22 78.6 0.0 8.1e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB12153.1 - 1.7e-06 28.1 0.3 0.049 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB12153.1 - 3.6e-05 23.4 0.1 8.5e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB12153.1 - 0.0012 18.8 0.1 0.002 18.1 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EGB12153.1 - 0.0013 18.2 0.0 0.69 9.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGB12153.1 - 0.0021 17.8 3.9 0.012 15.4 3.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB12153.1 - 0.0024 18.3 1.7 0.0056 17.1 1.7 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGB12153.1 - 0.0049 17.4 0.0 0.0072 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB12153.1 - 0.034 14.4 0.1 0.14 12.4 0.0 1.7 1 1 0 2 2 2 0 AAA domain RecA PF00154.21 EGB12153.1 - 0.041 13.3 0.2 0.064 12.7 0.2 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein NTPase_1 PF03266.15 EGB12153.1 - 0.19 11.7 0.1 0.45 10.4 0.1 1.6 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 EGB12153.1 - 0.23 11.5 0.1 0.47 10.5 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EGB12153.1 - 0.29 10.7 5.0 1.2 8.6 5.0 2.2 1 1 0 1 1 1 0 AAA domain Cupin_4 PF08007.12 EGB12154.1 - 9.1e-18 64.8 0.0 1.6e-10 40.9 0.0 2.5 3 0 0 3 3 3 2 Cupin superfamily protein Cupin_8 PF13621.6 EGB12154.1 - 1.7e-14 54.1 0.0 3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LLC1 PF14945.6 EGB12154.1 - 0.0003 21.3 0.1 0.00051 20.6 0.1 1.3 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Cupin_2 PF07883.11 EGB12154.1 - 0.00044 19.9 0.2 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 EGB12154.1 - 0.024 14.5 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 AraC-like ligand binding domain CRCB PF02537.15 EGB12155.1 - 9.9 6.6 10.5 1.2 9.5 3.7 2.7 2 1 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) PNP_UDP_1 PF01048.20 EGB12156.1 - 2.7e-05 23.5 0.0 9.4e-05 21.8 0.0 2.0 1 0 0 1 1 1 1 Phosphorylase superfamily PhyH PF05721.13 EGB12156.1 - 0.013 15.7 0.9 0.029 14.6 0.2 1.9 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) GCV_T_C PF08669.11 EGB12156.1 - 0.029 14.3 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain PMSR PF01625.21 EGB12157.1 - 1e-47 162.1 0.1 1.4e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase UCH PF00443.29 EGB12158.1 - 6.1e-46 157.0 0.0 6.7e-45 153.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGB12158.1 - 2.6e-18 66.7 0.0 6.6e-11 42.4 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGB12158.1 - 0.035 13.6 0.0 24 4.3 0.0 3.3 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.7 EGB12158.1 - 0.075 13.1 0.2 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.20 EGB12158.1 - 0.24 11.4 1.2 2.7 8.1 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin CpXC PF14353.6 EGB12158.1 - 0.37 10.8 1.1 11 6.0 0.1 2.5 2 1 0 2 2 2 0 CpXC protein Meckelin PF09773.9 EGB12159.1 - 3.8e-122 409.0 0.0 7.6e-122 408.0 0.0 1.5 1 1 0 1 1 1 1 Meckelin (Transmembrane protein 67) Zn_ribbon_SprT PF17283.2 EGB12159.1 - 0.049 13.5 0.0 0.32 10.9 0.0 2.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain IPPT PF01715.17 EGB12160.1 - 3.4e-48 164.4 0.0 7.3e-48 163.4 0.0 1.5 1 0 0 1 1 1 1 IPP transferase FYVE PF01363.21 EGB12160.1 - 7.3e-14 51.7 10.4 1.4e-13 50.7 10.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger IPT PF01745.16 EGB12160.1 - 1.2e-06 28.1 0.0 3.1e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 Isopentenyl transferase AAA_16 PF13191.6 EGB12160.1 - 0.0016 18.8 0.0 0.0095 16.3 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EGB12160.1 - 0.0019 18.3 0.0 0.0066 16.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain PPV_E1_C PF00519.17 EGB12160.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Hpr_kinase_C PF07475.12 EGB12160.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PH PF00169.29 EGB12160.1 - 0.23 12.0 0.0 0.71 10.4 0.0 1.8 1 1 0 1 1 1 0 PH domain FYVE_2 PF02318.16 EGB12160.1 - 0.47 10.7 6.5 0.93 9.7 6.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger EF-hand_1 PF00036.32 EGB12161.1 - 5.8e-13 47.4 0.4 1.7e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGB12161.1 - 1.4e-10 41.5 0.1 1.7e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB12161.1 - 2.2e-09 36.4 0.5 5e-06 25.8 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB12161.1 - 2.4e-08 33.3 0.2 0.00025 20.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB12161.1 - 2.8e-06 27.1 4.8 0.00017 21.4 0.4 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EGB12161.1 - 0.0018 18.2 0.5 0.064 13.2 0.1 2.0 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGB12161.1 - 0.016 15.5 0.0 0.018 15.4 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain UNC-93 PF05978.16 EGB12162.1 - 3.1e-13 49.7 1.8 3.1e-13 49.7 1.8 2.1 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 MMR_HSR1 PF01926.23 EGB12163.1 - 2.5e-18 66.2 0.0 4.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGB12163.1 - 0.00051 19.6 0.0 0.0079 15.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGB12163.1 - 0.00061 19.7 0.0 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGB12163.1 - 0.022 14.8 0.0 0.44 10.6 0.1 2.1 2 0 0 2 2 2 0 Dynamin family TniB PF05621.11 EGB12163.1 - 0.031 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MeaB PF03308.16 EGB12163.1 - 0.038 13.0 0.1 0.39 9.6 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EGB12163.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EGB12163.1 - 0.13 11.6 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 EGB12163.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Aldedh PF00171.22 EGB12164.1 - 6.7e-64 216.1 0.0 1.1e-63 215.4 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EMC1_C PF07774.13 EGB12164.1 - 2.4e-59 200.6 0.0 3.4e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EGB12164.1 - 9.6e-07 28.6 10.0 5.9e-06 26.0 7.6 2.7 2 0 0 2 2 2 1 PQQ-like domain Acid_PPase PF12689.7 EGB12165.1 - 1.6e-38 132.2 0.0 1.7e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Aa_trans PF01490.18 EGB12166.1 - 2e-80 270.5 9.5 2.2e-80 270.4 9.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3040 PF11239.8 EGB12166.1 - 0.093 13.0 0.5 0.093 13.0 0.5 4.7 3 2 0 4 4 4 0 Protein of unknown function (DUF3040) CreA PF05981.12 EGB12167.1 - 1.4e-34 118.9 0.1 2.7e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 CreA protein EF-hand_7 PF13499.6 EGB12167.1 - 4.1e-08 33.6 4.4 0.0015 19.0 0.8 3.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB12167.1 - 1.6e-07 30.7 0.5 0.085 12.8 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EGB12167.1 - 3.1e-07 29.6 1.0 0.12 12.0 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_1 PF00036.32 EGB12167.1 - 7.1e-07 28.3 5.7 0.089 12.4 0.2 3.5 3 0 0 3 3 3 2 EF hand TPR_2 PF07719.17 EGB12167.1 - 2.2e-05 24.2 35.4 0.038 14.1 4.5 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGB12167.1 - 0.0025 17.5 12.7 0.012 15.3 0.9 3.6 3 0 0 3 3 3 2 TPR repeat SPARC_Ca_bdg PF10591.9 EGB12167.1 - 0.091 13.1 1.3 1.3 9.4 0.3 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EGB12167.1 - 0.45 10.4 2.2 19 5.2 0.4 2.7 2 0 0 2 2 2 0 EF-hand domain pair TPR_16 PF13432.6 EGB12167.1 - 0.83 10.4 48.1 0.15 12.7 11.2 6.1 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12167.1 - 1.9 8.4 27.2 0.75 9.7 3.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB12167.1 - 8.2 7.0 23.4 1 9.9 4.7 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 EGB12168.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EGB12169.1 - 5.3e-32 111.2 0.0 6.2e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12169.1 - 1.6e-22 80.0 0.0 1.9e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB12169.1 - 1.8e-05 23.7 0.0 2.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB12169.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EGB12169.1 - 0.028 13.4 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain tRNA-synt_1c PF00749.21 EGB12170.1 - 2.4e-89 299.3 0.0 3e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGB12170.1 - 2.6e-44 151.2 0.0 3.8e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_bind PF01588.20 EGB12171.1 - 4.2e-21 74.9 0.0 4.7e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain Dus PF01207.17 EGB12172.1 - 8.4e-29 100.6 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Na_H_Exchanger PF00999.21 EGB12173.1 - 8.6e-71 238.7 26.0 1.1e-70 238.4 26.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PDR_CDR PF06422.12 EGB12173.1 - 0.33 10.9 1.5 0.55 10.2 0.1 2.0 2 0 0 2 2 2 0 CDR ABC transporter Ribosomal_L28e PF01778.17 EGB12174.1 - 8.8e-33 113.5 1.1 8.8e-33 113.5 1.1 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EGB12174.1 - 4.5e-28 97.8 12.9 7.3e-28 97.1 12.9 1.3 1 0 0 1 1 1 1 Mak16 protein C-terminal region mTERF PF02536.14 EGB12174.1 - 0.015 14.3 0.2 0.018 14.0 0.2 1.2 1 0 0 1 1 1 0 mTERF TUDOR_5 PF18359.1 EGB12179.1 - 6.5e-05 22.5 0.5 0.00014 21.5 0.5 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 SPX PF03105.19 EGB12179.1 - 0.52 10.2 3.8 1 9.2 0.3 2.2 2 0 0 2 2 2 0 SPX domain 2OG-FeII_Oxy_3 PF13640.6 EGB12180.1 - 3e-19 69.7 0.0 5.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGB12180.1 - 7.8e-05 23.1 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_5 PF13857.6 EGB12181.1 - 1.8e-26 91.8 3.1 5.2e-10 39.4 0.1 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB12181.1 - 2.1e-24 85.6 0.5 1.7e-10 41.2 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB12181.1 - 7.2e-23 81.0 0.0 1.7e-11 44.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB12181.1 - 4.5e-22 75.8 0.3 5.2e-05 23.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EGB12181.1 - 7.7e-22 76.7 0.5 3.4e-05 24.1 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat HALZ PF02183.18 EGB12182.1 - 0.00046 20.3 0.9 0.00073 19.7 0.9 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 EGB12182.1 - 0.002 18.1 0.7 0.0033 17.4 0.7 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF1640 PF07798.11 EGB12182.1 - 0.0081 16.2 0.0 0.0096 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) APC_N_CC PF16689.5 EGB12182.1 - 0.009 16.1 1.3 0.013 15.5 1.3 1.3 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain MAD PF05557.13 EGB12182.1 - 0.01 14.2 0.3 0.013 13.9 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIC PF04977.15 EGB12182.1 - 0.013 15.3 1.2 0.024 14.4 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator HOOK PF05622.12 EGB12182.1 - 0.015 13.5 0.1 0.015 13.5 0.1 1.1 1 0 0 1 1 1 0 HOOK protein bZIP_1 PF00170.21 EGB12182.1 - 0.015 15.4 0.4 0.032 14.3 0.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor JIP_LZII PF16471.5 EGB12182.1 - 0.033 14.4 1.7 0.057 13.6 1.7 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF4140 PF13600.6 EGB12182.1 - 0.068 13.6 0.1 0.068 13.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 EGB12182.1 - 0.093 13.1 0.6 0.42 11.0 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SNF2_N PF00176.23 EGB12183.1 - 6.1e-27 94.3 0.0 6.7e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EGB12183.1 - 0.00026 20.7 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 EGB12183.1 - 0.0017 18.4 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGB12184.1 - 9.2e-16 58.2 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SBF PF01758.16 EGB12185.1 - 3.2e-27 95.5 9.9 4.2e-27 95.1 9.9 1.1 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 EGB12185.1 - 1e-08 34.9 13.5 1.1e-08 34.7 13.5 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) OAD_beta PF03977.13 EGB12185.1 - 5.6e-05 22.3 7.2 9.6e-05 21.5 7.2 1.5 1 1 0 1 1 1 1 Na+-transporting oxaloacetate decarboxylase beta subunit TPR_17 PF13431.6 EGB12186.1 - 6.1e-06 26.2 0.4 0.31 11.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB12186.1 - 5.1e-05 23.1 28.4 1 9.6 0.2 8.2 7 0 0 7 7 7 3 Tetratricopeptide repeat F5_F8_type_C PF00754.25 EGB12186.1 - 0.00031 20.8 0.1 0.00063 19.9 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain Glyco_transf_41 PF13844.6 EGB12186.1 - 0.00036 19.1 0.0 0.00098 17.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 41 Glycos_transf_2 PF00535.26 EGB12186.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF5353 PF17304.2 EGB12186.1 - 0.11 12.3 0.1 0.61 9.9 0.1 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5353) TPR_8 PF13181.6 EGB12186.1 - 0.61 10.5 8.9 10 6.6 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12186.1 - 3.4 7.6 11.6 19 5.3 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB12186.1 - 4.2 7.6 37.7 0.36 11.0 9.9 6.5 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB12186.1 - 7.6 6.3 10.4 65 3.3 0.0 5.0 5 0 0 5 5 5 0 TPR repeat TPT PF03151.16 EGB12187.1 - 6.1e-12 45.5 14.6 7.2e-12 45.2 14.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DHDPS PF00701.22 EGB12188.1 - 8e-84 280.8 0.1 1e-83 280.4 0.1 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Saccharop_dh_N PF04455.12 EGB12188.1 - 1.6e-08 34.9 0.1 5.4e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region Cation_ATPase_C PF00689.21 EGB12189.1 - 2.8e-37 128.2 0.1 2.8e-37 128.2 0.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGB12189.1 - 2.3e-30 105.4 2.9 1.2e-29 103.1 0.4 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGB12189.1 - 2.8e-14 53.9 3.3 1.5e-08 35.2 1.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGB12189.1 - 3e-13 49.7 0.0 8.1e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGB12189.1 - 5.1e-10 38.9 0.0 1.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGB12189.1 - 9.3e-05 22.3 0.2 0.00079 19.2 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_18 PF00704.28 EGB12190.1 - 8.1e-22 78.3 0.0 1.1e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hydrolase_6 PF13344.6 EGB12192.1 - 2.4e-29 101.4 0.0 4e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB12192.1 - 1.8e-20 72.7 0.0 4.5e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGB12192.1 - 1.9e-09 38.1 0.1 2.6e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGB12192.1 - 6.2e-06 26.4 0.1 0.0023 18.1 0.0 2.7 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGB12192.1 - 0.0032 17.1 0.0 0.0072 16.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Thioredoxin PF00085.20 EGB12193.1 - 5.4e-17 61.7 0.0 8.1e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGB12193.1 - 0.0032 17.6 0.0 0.015 15.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Glutaredoxin PF00462.24 EGB12193.1 - 0.0083 16.3 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EGB12193.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EGB12193.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Orn_Arg_deC_N PF02784.16 EGB12194.1 - 1.5e-31 109.7 0.0 2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGB12194.1 - 4e-09 36.6 0.0 7.5e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Aldo_ket_red PF00248.21 EGB12195.1 - 1.2e-29 103.5 0.0 1.7e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aminotran_3 PF00202.21 EGB12196.1 - 1.9e-60 204.7 0.1 2.7e-60 204.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SpoVS PF04232.12 EGB12196.1 - 5.9e-09 35.5 1.7 1.4e-08 34.4 1.7 1.6 1 0 0 1 1 1 1 Stage V sporulation protein S (SpoVS) PC-Esterase PF13839.6 EGB12196.1 - 0.065 13.0 0.7 0.23 11.1 0.7 1.7 1 1 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p HAGH_C PF16123.5 EGB12198.1 - 1.8e-19 70.0 0.0 2.6e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGB12198.1 - 5.3e-14 52.7 1.8 1.6e-13 51.2 1.8 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGB12198.1 - 3.5e-05 23.4 0.5 0.00012 21.6 0.4 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain HSP70 PF00012.20 EGB12199.1 - 5.9e-263 873.5 7.9 7e-263 873.3 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGB12199.1 - 9.8e-16 57.5 0.0 1.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EGB12199.1 - 0.0093 15.0 0.1 0.081 11.9 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 EGB12199.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Cupin_4 PF08007.12 EGB12200.1 - 1.1e-05 25.0 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EGB12200.1 - 0.0014 18.4 0.0 0.011 15.5 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EGB12200.1 - 0.0067 16.1 0.0 0.038 13.7 0.0 2.2 2 0 0 2 2 2 1 Cupin domain KH_6 PF15985.5 EGB12201.1 - 1.1e-10 41.6 0.5 2.5e-10 40.6 0.5 1.6 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 EGB12201.1 - 0.0022 17.7 0.5 0.0054 16.5 0.5 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PALP PF00291.25 EGB12202.1 - 4.8e-62 210.0 5.8 5.8e-62 209.7 5.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 EGB12202.1 - 0.16 11.8 0.8 0.29 11.0 0.4 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein TPR_4 PF07721.14 EGB12202.1 - 2.5 9.0 8.4 18 6.3 3.9 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Laminin_II PF06009.12 EGB12203.1 - 0.00043 20.3 6.9 1 9.4 0.2 3.9 3 0 0 3 3 3 2 Laminin Domain II Baculo_PEP_C PF04513.12 EGB12203.1 - 0.0097 16.0 3.7 17 5.4 0.0 5.1 5 0 0 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 EGB12203.1 - 0.036 14.4 5.1 1.1 9.6 0.1 4.9 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 EGB12203.1 - 1.4 9.4 14.0 5 7.6 0.4 5.1 5 1 0 5 5 5 0 Cell division protein ZapB NPV_P10 PF05531.12 EGB12203.1 - 3.3 8.2 5.4 81 3.8 0.5 4.6 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EGB12203.1 - 3.7 7.9 10.2 51 4.2 0.0 4.6 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 EGB12203.1 - 7.3 6.7 7.1 7.9 6.6 0.1 3.9 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 EGB12203.1 - 8 5.2 8.8 0.58 9.0 2.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Sacchrp_dh_NADP PF03435.18 EGB12204.1 - 3.9e-05 23.9 0.2 0.00012 22.3 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TPP_enzyme_N PF02776.18 EGB12204.1 - 0.016 14.9 0.1 1.8 8.1 0.0 2.3 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Myosin_head PF00063.21 EGB12205.1 - 2.4e-160 535.0 0.0 6.1e-160 533.7 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_6 PF12774.7 EGB12205.1 - 0.049 12.6 0.1 0.081 11.9 0.1 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 EGB12205.1 - 0.084 13.2 2.5 0.11 12.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 EGB12205.1 - 0.16 11.2 0.1 0.16 11.2 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin FTCD_C PF04961.12 EGB12205.1 - 0.66 9.7 3.2 0.66 9.7 0.1 2.2 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Pkinase PF00069.25 EGB12206.1 - 7.5e-61 205.8 0.0 1.3e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EGB12206.1 - 2e-39 133.5 0.1 1.4e-19 69.9 0.0 3.3 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGB12206.1 - 2.7e-25 89.1 0.0 4.8e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB12206.1 - 0.0022 18.0 0.0 0.063 13.2 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.21 EGB12207.1 - 1.8e-08 34.1 0.0 3.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ABC_tran PF00005.27 EGB12208.1 - 1.5e-42 145.3 0.0 5e-20 72.4 0.0 3.1 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EGB12208.1 - 2.4e-17 63.7 0.0 4e-06 26.9 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB12208.1 - 6.5e-10 38.8 0.0 1.4e-06 27.9 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB12208.1 - 1e-07 31.6 0.1 0.019 14.7 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGB12208.1 - 6.5e-06 26.6 0.5 0.045 14.1 0.5 2.7 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGB12208.1 - 1.1e-05 25.5 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 EGB12208.1 - 3.3e-05 24.2 0.0 0.019 15.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGB12208.1 - 0.00011 22.1 0.0 0.68 9.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran_Xtn PF12848.7 EGB12208.1 - 0.00022 21.2 4.0 0.00022 21.2 4.0 2.1 3 0 0 3 3 2 1 ABC transporter AAA_33 PF13671.6 EGB12208.1 - 0.00051 20.2 0.3 0.068 13.3 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EGB12208.1 - 0.00067 19.5 0.1 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGB12208.1 - 0.0012 19.4 5.7 1.3 9.4 0.0 3.3 3 1 0 3 3 3 2 AAA domain Roc PF08477.13 EGB12208.1 - 0.0037 17.5 0.0 0.7 10.1 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGB12208.1 - 0.006 16.6 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGB12208.1 - 0.0067 16.8 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 EGB12208.1 - 0.0069 16.8 0.0 0.76 10.2 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB12208.1 - 0.0093 16.2 0.5 9.8 6.4 0.1 3.4 2 2 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGB12208.1 - 0.017 14.7 3.3 0.085 12.4 0.1 3.4 3 1 1 4 4 4 0 AAA domain TsaE PF02367.17 EGB12208.1 - 0.024 14.6 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGB12208.1 - 0.042 13.6 0.1 10 5.8 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 EGB12208.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 EGB12208.1 - 0.047 13.4 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGB12208.1 - 0.078 12.5 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGB12208.1 - 0.11 12.2 0.1 15 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain CobA_CobO_BtuR PF02572.15 EGB12208.1 - 0.11 12.7 0.2 3.5 7.9 0.0 3.0 3 1 0 3 3 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DLIC PF05783.11 EGB12208.1 - 0.12 11.2 0.0 0.42 9.4 0.0 1.7 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) TPR_4 PF07721.14 EGB12208.1 - 4.9 8.1 0.0 4.9 8.1 0.0 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat PspA_IM30 PF04012.12 EGB12209.1 - 5.8e-47 160.1 26.4 5.8e-47 160.1 26.4 1.4 2 0 0 2 2 2 1 PspA/IM30 family LAGLIDADG_WhiA PF14527.6 EGB12209.1 - 0.059 13.4 0.2 0.16 12.0 0.2 1.8 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Spc7 PF08317.11 EGB12209.1 - 0.54 9.1 18.6 6.2 5.6 17.8 2.4 1 1 0 1 1 1 0 Spc7 kinetochore protein CemA PF03040.14 EGB12209.1 - 3.2 7.6 4.6 1.1 9.2 0.8 1.8 1 1 1 2 2 2 0 CemA family DUF2408 PF10303.9 EGB12209.1 - 6.6 7.3 11.4 45 4.6 11.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Fib_alpha PF08702.10 EGB12209.1 - 9.9 6.3 11.5 18 5.5 1.5 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_1 PF00036.32 EGB12210.1 - 2.6e-21 73.5 2.1 0.00021 20.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGB12210.1 - 3.7e-20 70.1 0.2 0.002 17.9 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGB12210.1 - 1.4e-19 70.3 0.5 1.1e-08 35.3 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB12210.1 - 4.2e-12 45.0 3.9 0.014 14.9 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB12210.1 - 1.2e-08 34.6 1.6 0.17 11.7 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain pair Methyltransf_32 PF13679.6 EGB12210.1 - 3.1e-07 30.5 2.9 0.0027 17.7 2.8 2.8 2 1 1 3 3 3 2 Methyltransferase domain zf-B_box PF00643.24 EGB12210.1 - 4.2e-07 30.0 23.2 4e-06 26.9 8.1 2.4 2 0 0 2 2 2 2 B-box zinc finger Methyltransf_25 PF13649.6 EGB12210.1 - 2.1e-06 28.4 0.6 6.2e-06 26.8 0.6 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB12210.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain EF-hand_4 PF12763.7 EGB12210.1 - 0.0028 17.6 0.3 0.87 9.6 0.0 3.2 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Met_10 PF02475.16 EGB12210.1 - 0.0072 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EGB12210.1 - 0.02 14.4 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RRM_1 PF00076.22 EGB12210.1 - 0.033 14.0 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Topoisom_bac PF01131.20 EGB12211.1 - 2.2e-95 320.1 0.0 2.6e-95 319.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGB12211.1 - 3.8e-18 65.6 0.0 6.7e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Toprim domain VPS9 PF02204.18 EGB12212.1 - 2.5e-18 66.2 0.0 4.2e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 EGB12212.1 - 4.3e-06 26.7 0.0 7.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 PX domain PDZ_6 PF17820.1 EGB12212.1 - 0.0054 16.6 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGB12212.1 - 0.15 12.4 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.24 EGB12212.1 - 0.22 11.9 0.0 0.42 11.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PRT_C PF08372.10 EGB12212.1 - 1 9.1 3.7 2.4 7.9 0.2 2.3 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal D123 PF07065.14 EGB12213.1 - 3.8e-29 101.8 0.0 4.3e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4476 PF14771.6 EGB12214.1 - 2.1e-15 56.8 0.0 1.2e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) DUF4197 PF13852.6 EGB12214.1 - 1e-09 38.4 0.5 1.7e-09 37.6 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4197) Aa_trans PF01490.18 EGB12215.1 - 4e-67 226.7 10.0 5e-67 226.4 10.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGB12215.1 - 3.5e-06 26.3 7.1 3.5e-06 26.3 7.1 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family UL41A PF17591.2 EGB12215.1 - 4 7.6 8.8 4.6 7.4 0.2 3.0 3 0 0 3 3 3 0 Herpesvirus UL41A Cupin_8 PF13621.6 EGB12216.1 - 1.6e-08 34.6 0.0 3.8e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGB12216.1 - 6.5e-08 32.4 0.2 1e-07 31.7 0.2 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGB12216.1 - 0.0021 18.5 0.0 0.0042 17.5 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 EGB12216.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 EGB12216.1 - 0.041 13.6 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Rho_Binding PF08912.11 EGB12217.1 - 1.8 9.4 4.5 6.3 7.7 0.4 3.5 3 1 0 3 3 3 0 Rho Binding Chloroa_b-bind PF00504.21 EGB12218.1 - 9.3e-27 94.5 0.0 1.2e-26 94.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein GST_N PF02798.20 EGB12219.1 - 4.2e-18 65.5 0.0 8.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGB12219.1 - 7.6e-15 55.1 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB12219.1 - 5.7e-14 52.1 0.1 9e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGB12219.1 - 4.2e-11 43.0 0.0 7.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB12219.1 - 1.9e-10 40.6 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGB12219.1 - 3.4e-08 33.6 0.0 5.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cation_efflux PF01545.21 EGB12220.1 - 3.9e-27 95.3 4.6 4.8e-27 95.0 4.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGB12220.1 - 0.0028 17.7 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter EF1_GNE PF00736.19 EGB12221.1 - 3.9e-20 71.8 1.7 7.5e-20 70.9 1.7 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Ribosomal_60s PF00428.19 EGB12221.1 - 1.7e-06 28.5 3.6 1.7e-06 28.5 3.6 3.0 2 1 1 3 3 3 1 60s Acidic ribosomal protein DEC-1_N PF04625.13 EGB12221.1 - 0.36 9.8 6.0 0.63 9.0 6.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Methyltransf_3 PF01596.17 EGB12222.1 - 1.7e-13 50.2 0.0 2.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGB12222.1 - 6.5e-10 40.0 0.4 1.4e-09 38.9 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB12222.1 - 0.0055 17.4 0.1 0.084 13.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EGB12222.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rhodopsin_N PF10413.9 EGB12222.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin SelR PF01641.18 EGB12223.1 - 1.5e-30 105.7 0.0 1.7e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 SelR domain GFO_IDH_MocA PF01408.22 EGB12225.1 - 2.2e-22 80.1 0.4 2.9e-22 79.7 0.4 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 EGB12225.1 - 0.00083 19.4 0.1 0.0034 17.4 0.1 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGB12225.1 - 0.0019 18.4 0.9 0.041 14.1 0.9 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TPT PF03151.16 EGB12226.1 - 1.7e-53 181.9 0.2 1.9e-53 181.7 0.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB12226.1 - 3.3e-12 46.7 6.1 3.1e-07 30.6 1.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGB12226.1 - 1.1e-05 24.8 1.5 2.4e-05 23.7 1.5 1.5 1 1 0 1 1 1 1 UAA transporter family DUF3269 PF11673.8 EGB12226.1 - 0.066 13.6 0.8 0.92 9.9 0.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3269) Na_Ca_ex PF01699.24 EGB12227.1 - 1.8e-48 164.3 38.6 1.1e-25 90.3 19.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein COX7a PF02238.15 EGB12227.1 - 8.2 6.9 5.9 55 4.3 5.9 2.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII YGGT PF02325.17 EGB12228.1 - 6.2e-14 52.2 4.6 8e-14 51.8 4.6 1.1 1 0 0 1 1 1 1 YGGT family ABC_membrane PF00664.23 EGB12229.1 - 1.3e-96 323.4 12.0 7.4e-49 166.8 2.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGB12229.1 - 3.5e-62 208.9 0.0 2.6e-30 105.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGB12229.1 - 1.7e-12 47.3 0.0 7.1e-05 22.4 0.0 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGB12229.1 - 3.4e-06 27.4 1.6 0.28 11.5 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGB12229.1 - 4.6e-06 26.3 0.3 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGB12229.1 - 1.1e-05 25.4 0.2 0.14 12.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB12229.1 - 3.7e-05 24.2 14.5 0.0062 16.9 0.1 4.1 4 2 1 5 5 4 2 AAA ATPase domain AAA_25 PF13481.6 EGB12229.1 - 5.4e-05 22.9 4.4 0.31 10.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 EGB12229.1 - 0.00025 20.6 0.0 0.83 9.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EGB12229.1 - 0.00029 20.6 0.0 0.12 12.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGB12229.1 - 0.00031 20.9 4.1 0.85 9.9 0.4 4.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EGB12229.1 - 0.00039 20.9 0.1 1.9 8.9 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGB12229.1 - 0.0016 18.6 0.1 4 7.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EGB12229.1 - 0.0017 18.5 0.0 2.8 8.0 0.0 2.7 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_10 PF12846.7 EGB12229.1 - 0.0029 16.6 0.0 0.38 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain ABC_ATPase PF09818.9 EGB12229.1 - 0.0049 15.7 0.2 2.2 7.0 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 EGB12229.1 - 0.0062 16.5 0.3 2.7 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EGB12229.1 - 0.0063 16.4 0.1 0.22 11.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 EGB12229.1 - 0.0098 16.3 0.1 4.1 7.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 EGB12229.1 - 0.01 15.9 0.1 3.3 7.8 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EGB12229.1 - 0.016 14.5 0.1 2.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 EGB12229.1 - 0.029 13.5 0.0 3.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SRP54 PF00448.22 EGB12229.1 - 0.034 13.8 0.1 4.5 6.9 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EGB12229.1 - 0.048 13.4 0.1 0.048 13.4 0.1 4.3 4 1 0 4 4 3 0 AAA domain NACHT PF05729.12 EGB12229.1 - 0.065 13.1 1.5 20 5.1 0.0 3.5 4 0 0 4 4 4 0 NACHT domain AAA_21 PF13304.6 EGB12229.1 - 0.07 12.9 0.0 11 5.7 0.0 3.0 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGB12229.1 - 0.18 11.5 0.0 11 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGB12229.1 - 0.2 12.1 0.2 18 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Jun PF03957.13 EGB12229.1 - 0.81 9.5 3.3 22 4.8 0.3 2.4 2 0 0 2 2 2 0 Jun-like transcription factor Histone PF00125.24 EGB12231.1 - 6.6e-16 58.9 0.0 9.5e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGB12231.1 - 3.4e-14 52.3 1.3 6.7e-14 51.3 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGB12231.1 - 0.0032 17.7 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IMS_C PF11799.8 EGB12231.1 - 0.12 13.1 0.0 0.14 12.8 0.0 1.3 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain DnaJ PF00226.31 EGB12232.1 - 1.7e-13 50.5 0.4 2.1e-13 50.2 0.4 1.1 1 0 0 1 1 1 1 DnaJ domain P4Ha_N PF08336.11 EGB12232.1 - 0.12 12.4 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3105 PF11303.8 EGB12233.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) CH PF00307.31 EGB12234.1 - 8.4e-10 38.8 0.0 2.2e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain SSF PF00474.17 EGB12234.1 - 4.3e-06 25.9 14.9 8.2e-06 24.9 14.9 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Cytochrom_B_C PF00032.17 EGB12234.1 - 0.24 11.7 1.3 0.54 10.6 0.1 2.3 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD GSH_synth_ATP PF03917.17 EGB12235.1 - 3.8e-114 381.3 0.0 4.4e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGB12235.1 - 1.2e-26 93.1 0.0 3.2e-26 91.8 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic glutathione synthase FliT PF05400.13 EGB12235.1 - 0.0019 19.0 1.1 0.007 17.1 1.1 2.0 1 0 0 1 1 1 1 Flagellar protein FliT COG7 PF10191.9 EGB12236.1 - 1.2e-37 129.6 0.0 2.4e-30 105.5 0.0 2.9 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) Hrs_helical PF12210.8 EGB12236.1 - 0.043 14.3 0.1 9.6 6.8 0.1 2.8 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate NPV_P10 PF05531.12 EGB12236.1 - 0.09 13.3 0.1 4.1 7.9 0.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_C2 PF00648.21 EGB12237.1 - 1.1e-29 103.4 0.0 1.2e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease DNA_pol_B PF00136.21 EGB12238.1 - 2.1e-13 49.8 0.0 2.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 EGB12238.1 - 0.23 10.3 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 EGB12239.1 - 2.1e-40 138.8 0.0 2.8e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B Helicase_C_2 PF13307.6 EGB12240.1 - 2.1e-41 142.0 0.0 3.8e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGB12240.1 - 7.8e-24 84.2 0.0 1.3e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 LCM PF04072.14 EGB12240.1 - 2.3e-15 57.1 0.8 5.3e-15 55.9 0.8 1.6 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase ResIII PF04851.15 EGB12240.1 - 3.3e-07 30.5 0.0 1.7e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit LIM PF00412.22 EGB12240.1 - 4e-07 30.1 1.0 3.5e-06 27.2 0.2 2.7 3 0 0 3 3 3 1 LIM domain DEAD PF00270.29 EGB12240.1 - 9.1e-05 22.3 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 EGB12240.1 - 0.059 12.8 0.2 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EGB12240.1 - 0.28 10.9 5.4 0.28 10.9 0.1 3.4 4 0 0 4 4 4 0 AAA domain DUF563 PF04577.14 EGB12241.1 - 8.5e-21 75.0 0.0 1.9e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Paf1 PF03985.13 EGB12241.1 - 1.1e-20 74.0 0.1 1e-19 70.9 0.0 2.3 2 1 0 2 2 2 1 Paf1 Ank_2 PF12796.7 EGB12241.1 - 2.3e-07 31.3 0.0 5.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB12241.1 - 0.00042 20.6 0.1 0.057 13.8 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12241.1 - 0.00064 20.0 0.1 0.06 13.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGB12241.1 - 0.0062 16.9 0.0 0.55 10.8 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGB12241.1 - 0.0079 16.8 0.1 0.02 15.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF4611 PF15387.6 EGB12241.1 - 2.5 8.4 5.4 6.7 7.0 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) UQ_con PF00179.26 EGB12242.1 - 5.7e-21 74.6 0.0 6.9e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Arylsulfotrans PF05935.11 EGB12243.1 - 0.00043 19.3 0.0 0.00067 18.7 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) HEAT_2 PF13646.6 EGB12244.1 - 2e-16 60.1 8.2 5.8e-09 36.2 1.1 2.3 2 0 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 EGB12244.1 - 3e-12 46.0 17.9 0.011 16.4 0.7 5.1 5 0 0 5 5 5 4 PBS lyase HEAT-like repeat HEAT PF02985.22 EGB12244.1 - 0.0033 17.5 2.7 6.7 7.3 0.0 4.5 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EGB12244.1 - 0.64 10.6 10.1 1.4 9.5 1.3 4.1 2 2 2 4 4 4 0 HEAT-like repeat ABC1 PF03109.16 EGB12245.1 - 1e-25 90.2 0.0 1.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family GDE_N_bis PF14742.6 EGB12245.1 - 0.0038 16.8 0.1 0.16 11.6 0.1 2.2 2 0 0 2 2 2 2 N-terminal domain of (some) glycogen debranching enzymes CPSase_L_D2 PF02786.17 EGB12246.1 - 1.6e-109 364.3 0.0 1e-76 257.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EGB12246.1 - 1.8e-48 163.6 0.0 3.3e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EGB12246.1 - 1.5e-37 129.3 0.0 3e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EGB12246.1 - 7.3e-33 113.5 0.0 1.3e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 EGB12246.1 - 1.1e-15 57.6 0.0 4.6e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 EGB12246.1 - 6.8e-12 45.3 0.0 5.7e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGB12246.1 - 9e-11 41.7 0.0 7e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGB12246.1 - 3.5e-09 36.5 0.0 0.0024 17.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EGB12246.1 - 0.0029 17.7 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EGB12246.1 - 0.0048 16.7 0.1 0.82 9.4 0.1 2.8 1 1 0 1 1 1 1 Peptidase C26 Mito_carr PF00153.27 EGB12247.1 - 9.9e-18 63.9 2.6 4.9e-08 32.8 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein PAPS_reduct PF01507.19 EGB12248.1 - 6.1e-17 62.2 0.0 6.9e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family cNMP_binding PF00027.29 EGB12249.1 - 2.7e-17 62.6 0.1 4.5e-17 61.9 0.0 1.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Mpv17_PMP22 PF04117.12 EGB12250.1 - 3.3e-17 62.5 0.6 5.9e-17 61.7 0.6 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4205 PF13898.6 EGB12251.1 - 8.7e-47 159.7 0.0 9.7e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Aldo_ket_red PF00248.21 EGB12252.1 - 1.7e-36 125.9 0.0 2e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAP_PilO PF06864.12 EGB12252.1 - 0.042 12.7 0.0 1.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Pilin accessory protein (PilO) PTCB-BRCT PF12738.7 EGB12253.1 - 2.4e-07 30.6 0.1 1.7e-05 24.7 0.0 2.8 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EGB12253.1 - 0.024 15.0 0.0 0.8 10.1 0.0 2.8 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain cNMP_binding PF00027.29 EGB12254.1 - 1.4e-14 53.9 0.0 5.1e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DHHA2 PF02833.14 EGB12254.1 - 8.4e-14 52.0 0.0 1.6e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EGB12254.1 - 4e-07 30.2 0.1 9.3e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 DHH family F5_F8_type_C PF00754.25 EGB12254.1 - 0.00041 20.5 0.0 4.3 7.5 0.0 3.7 3 0 0 3 3 3 2 F5/8 type C domain LRR_8 PF13855.6 EGB12254.1 - 0.0032 17.2 0.6 0.064 13.0 0.2 2.7 2 2 0 2 2 2 1 Leucine rich repeat Phage_GP20 PF06810.11 EGB12254.1 - 0.74 9.6 4.1 1.6 8.5 4.1 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 Fez1 PF06818.15 EGB12254.1 - 9.2 6.7 10.4 23 5.4 10.4 1.6 1 0 0 1 1 1 0 Fez1 TPT PF03151.16 EGB12255.1 - 4.7e-11 42.6 0.7 5.5e-11 42.3 0.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Pkinase PF00069.25 EGB12256.1 - 5.8e-57 193.1 0.0 7.1e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12256.1 - 4.9e-24 85.0 0.0 6.9e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB12256.1 - 0.054 13.4 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB12256.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ras PF00071.22 EGB12257.1 - 8.6e-51 171.8 0.7 1e-50 171.5 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB12257.1 - 2.2e-34 118.3 0.2 3.8e-34 117.5 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB12257.1 - 1.5e-15 57.0 0.1 1.8e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGB12257.1 - 3.6e-06 26.5 0.0 4.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGB12257.1 - 9.7e-06 25.1 0.1 1.4e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGB12257.1 - 3.8e-05 23.7 0.4 0.026 14.4 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EGB12257.1 - 0.00013 21.6 0.7 0.00042 19.9 0.4 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGB12257.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGB12257.1 - 0.0062 16.9 0.0 0.0097 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EGB12257.1 - 0.018 15.1 0.2 0.044 13.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGB12257.1 - 0.019 14.9 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.18 EGB12257.1 - 0.019 14.5 0.3 0.25 10.8 0.3 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B TsaE PF02367.17 EGB12257.1 - 0.046 13.7 0.1 0.092 12.7 0.1 1.8 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 EGB12257.1 - 0.076 12.0 0.1 0.65 8.9 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EGB12257.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 EGB12257.1 - 0.12 12.8 0.2 0.57 10.6 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB12257.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain LRR_9 PF14580.6 EGB12258.1 - 4.4e-09 36.1 0.0 5.4e-06 26.0 0.3 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 EGB12258.1 - 1.3e-07 31.3 5.4 1.2e-05 25.0 1.0 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGB12258.1 - 2.9e-07 30.7 5.0 5.5e-05 23.5 1.0 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGB12258.1 - 0.006 16.6 1.4 5.4 7.3 0.1 3.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 EGB12258.1 - 0.27 11.9 2.6 90 4.2 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat Acyltransferase PF01553.21 EGB12260.1 - 2.2e-17 62.9 0.0 4.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGB12260.1 - 2.8e-06 27.3 0.0 5.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus HTH_33 PF13592.6 EGB12260.1 - 0.0028 17.3 0.0 8.3 6.1 0.0 4.1 3 0 0 3 3 3 2 Winged helix-turn helix EF-hand_8 PF13833.6 EGB12260.1 - 0.067 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Chalcone_3 PF16036.5 EGB12261.1 - 0.0057 16.8 0.0 0.023 14.8 0.0 1.9 1 1 0 1 1 1 1 Chalcone isomerase-like RFC1 PF08519.12 EGB12262.1 - 0.18 12.0 0.8 5.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Lactonase PF10282.9 EGB12263.1 - 2.8e-55 188.0 0.0 3.1e-53 181.2 0.0 3.1 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF1800 PF08811.11 EGB12264.1 - 3.3e-50 171.4 0.0 4.1e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) DUF1501 PF07394.12 EGB12265.1 - 3.5e-38 131.7 1.0 2.4e-37 129.0 1.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) DUF5596 PF18082.1 EGB12265.1 - 0.024 14.5 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) GCV_T PF01571.21 EGB12266.1 - 1e-70 238.1 0.0 2.3e-70 236.9 0.0 1.5 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGB12266.1 - 3.8e-19 68.4 0.2 7e-19 67.5 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EGB12266.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family Isochorismatase PF00857.20 EGB12267.1 - 7.6e-43 146.7 0.0 9.7e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Amidohydro_3 PF07969.11 EGB12267.1 - 0.013 15.0 0.2 0.032 13.7 0.1 1.7 2 0 0 2 2 2 0 Amidohydrolase family Isochorismatase PF00857.20 EGB12268.1 - 3.8e-38 131.4 0.0 8.2e-38 130.3 0.0 1.5 2 0 0 2 2 2 1 Isochorismatase family Catalase_C PF18011.1 EGB12268.1 - 0.0084 15.7 0.2 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 C-terminal domain found in long catalases EF-hand_7 PF13499.6 EGB12269.1 - 2.4e-18 66.3 1.3 3.9e-13 49.6 0.5 1.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB12269.1 - 1.1e-14 52.8 1.1 9.9e-07 27.9 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB12269.1 - 1.8e-13 50.1 3.1 1.3e-07 31.3 1.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB12269.1 - 1.1e-11 43.6 0.2 1.4e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB12269.1 - 2.1e-10 39.6 0.1 0.00049 19.5 0.0 2.3 2 0 0 2 2 2 2 EF hand MotA_activ PF09114.10 EGB12269.1 - 0.0031 17.6 0.0 0.0037 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor MotA, activation domain SPARC_Ca_bdg PF10591.9 EGB12269.1 - 0.0074 16.6 0.0 0.0081 16.5 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 EGB12269.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 Ca2+ insensitive EF hand Mei4 PF13971.6 EGB12269.1 - 0.15 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 PUNUT PF16913.5 EGB12271.1 - 3.3e-06 26.6 0.2 5.6e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 EGB12271.1 - 0.00011 22.4 10.2 0.00011 22.4 10.2 3.7 2 2 1 3 3 3 1 EamA-like transporter family TPT PF03151.16 EGB12271.1 - 0.0004 19.8 2.6 0.00095 18.6 2.4 1.7 1 1 1 2 2 2 1 Triose-phosphate Transporter family SGS PF05002.15 EGB12272.1 - 0.00016 21.7 1.2 0.00026 21.0 1.2 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EGB12272.1 - 0.0065 17.5 0.1 0.0087 17.1 0.1 1.2 1 0 0 1 1 1 1 CS domain PseudoU_synth_2 PF00849.22 EGB12273.1 - 2.6e-12 47.1 0.0 1.4e-11 44.7 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase DivIC PF04977.15 EGB12274.1 - 0.77 9.6 5.1 5.2 6.9 0.6 2.6 2 0 0 2 2 2 0 Septum formation initiator Peptidase_M20 PF01546.28 EGB12275.1 - 9.6e-33 113.6 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGB12275.1 - 1.3e-15 57.2 0.0 2.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGB12275.1 - 3.5e-06 26.8 0.3 1.7e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 EGB12275.1 - 0.003 16.6 0.0 0.045 12.8 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase MFS_1 PF07690.16 EGB12276.1 - 5.6e-32 111.0 28.9 5.6e-32 111.0 28.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGB12276.1 - 4.6e-06 25.8 6.3 0.00023 20.2 3.5 2.1 1 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EGB12276.1 - 0.0027 16.7 22.2 0.06 12.2 7.2 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2530 PF10745.9 EGB12276.1 - 0.035 14.3 0.6 0.035 14.3 0.6 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) TspO_MBR PF03073.15 EGB12277.1 - 5.9e-24 84.7 7.5 6.7e-24 84.5 7.5 1.0 1 0 0 1 1 1 1 TspO/MBR family DNA_pol_A_exo1 PF01612.20 EGB12278.1 - 2e-14 53.7 0.0 3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease tRNA_edit PF04073.15 EGB12278.1 - 1.9e-13 50.6 1.0 4.1e-13 49.5 0.3 1.8 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain NDK PF00334.19 EGB12280.1 - 2e-47 160.6 0.0 2.7e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase WD40 PF00400.32 EGB12281.1 - 1.6e-11 44.5 22.9 0.00019 22.2 0.2 9.8 11 0 0 11 11 11 3 WD domain, G-beta repeat AAA_25 PF13481.6 EGB12281.1 - 9.3e-07 28.6 1.1 3.6e-06 26.7 1.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB12281.1 - 5e-06 27.0 0.1 1.7e-05 25.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGB12281.1 - 0.0031 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB12281.1 - 0.0054 16.5 0.8 0.0054 16.5 0.8 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB12281.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain VID27 PF08553.10 EGB12281.1 - 0.24 10.4 0.3 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PQQ PF01011.21 EGB12281.1 - 0.94 9.5 10.9 6.7 6.8 0.4 4.8 5 0 0 5 5 5 0 PQQ enzyme repeat PQQ_3 PF13570.6 EGB12281.1 - 7.8 7.1 29.1 11 6.6 0.5 8.0 7 1 0 7 7 7 0 PQQ-like domain AAA_12 PF13087.6 EGB12282.1 - 3.1e-19 69.4 0.0 3.4e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB12282.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EGB12282.1 - 0.096 11.9 0.1 0.096 11.9 0.1 1.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aminotran_1_2 PF00155.21 EGB12283.1 - 3.2e-51 174.6 0.0 3.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGB12283.1 - 0.0067 15.7 0.1 0.15 11.4 0.0 2.4 2 1 0 2 2 2 1 Beta-eliminating lyase Alliinase_C PF04864.13 EGB12283.1 - 0.24 10.3 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Allinase Raptor_N PF14538.6 EGB12284.1 - 2e-58 196.5 0.0 2.6e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EGB12285.1 - 0.00044 21.0 1.1 0.69 10.9 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 EGB12286.1 - 2e-154 508.5 76.4 2.2e-23 83.1 5.4 7.3 7 0 0 7 7 7 7 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 EGB12286.1 - 1.1e-22 80.6 0.5 0.033 13.9 0.0 8.6 7 4 0 7 7 7 6 Pentaxin family Laminin_G_2 PF02210.24 EGB12286.1 - 3.5e-17 63.1 14.3 0.36 11.4 0.1 7.5 7 0 0 7 7 7 6 Laminin G domain Chlorovi_GP_rpt PF06598.11 EGB12286.1 - 7e-07 29.2 0.0 1e+02 3.1 0.0 7.4 7 0 0 7 7 7 0 Chlorovirus glycoprotein repeat DUF1080 PF06439.11 EGB12286.1 - 9.9e-05 22.5 0.0 51 3.9 0.0 6.3 7 0 0 7 7 7 0 Domain of Unknown Function (DUF1080) DUF1737 PF08410.10 EGB12286.1 - 0.0014 18.5 0.0 28 4.7 0.0 6.0 7 0 0 7 7 7 1 Domain of unknown function (DUF1737) Glyco_hydro_32N PF00251.20 EGB12287.1 - 5.4e-17 62.3 0.0 1.3e-16 61.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EGB12287.1 - 0.017 15.1 0.0 0.1 12.6 0.0 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal Ubie_methyltran PF01209.18 EGB12288.1 - 1.8e-42 145.3 0.0 2e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGB12288.1 - 7.2e-13 49.1 0.0 1.1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB12288.1 - 1.4e-11 44.9 0.0 2.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB12288.1 - 5e-10 39.5 0.0 6.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB12288.1 - 1.4e-09 37.9 0.0 1.8e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB12288.1 - 2.2e-07 31.5 0.0 3.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB12288.1 - 0.0017 17.7 0.0 0.024 13.9 0.0 2.0 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 EGB12288.1 - 0.073 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.19 EGB12288.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGB12288.1 - 0.2 11.2 0.1 0.28 10.7 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 EGB12288.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FKBP_C PF00254.28 EGB12289.1 - 2.4e-18 66.2 0.0 3e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase eIF-6 PF01912.18 EGB12290.1 - 2.7e-77 258.6 0.4 4e-77 258.1 0.2 1.3 2 0 0 2 2 2 1 eIF-6 family PHD PF00628.29 EGB12291.1 - 2.2e-12 46.7 27.7 1.5e-06 28.0 4.4 2.8 3 0 0 3 3 3 2 PHD-finger Acetyltransf_10 PF13673.7 EGB12291.1 - 2.9e-08 33.7 0.0 4.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGB12291.1 - 1.1e-07 31.7 0.1 1.9e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EGB12291.1 - 1.1e-07 32.1 0.1 2.2e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGB12291.1 - 7.9e-07 29.4 0.0 1.7e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD_2 PF13831.6 EGB12291.1 - 6.1e-05 22.5 16.8 0.044 13.3 8.7 2.9 2 0 0 2 2 2 2 PHD-finger Acetyltransf_9 PF13527.7 EGB12291.1 - 0.00078 19.5 0.1 0.0016 18.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cwf_Cwc_15 PF04889.12 EGB12291.1 - 0.068 12.9 0.9 0.11 12.2 0.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TUDOR_5 PF18359.1 EGB12291.1 - 0.15 11.7 5.5 0.89 9.3 5.5 2.2 1 1 0 1 1 1 0 Histone methyltransferase Tudor domain 1 PBP1_TM PF14812.6 EGB12291.1 - 0.54 10.7 11.6 0.093 13.1 7.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-HC5HC2H_2 PF13832.6 EGB12291.1 - 0.69 10.1 17.4 0.79 9.9 7.4 2.9 2 1 1 3 3 3 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGB12291.1 - 1.6 9.1 19.8 0.24 11.7 8.5 3.1 2 1 1 3 3 3 0 PHD-like zinc-binding domain CENP-B_dimeris PF09026.10 EGB12291.1 - 5.1 7.5 11.5 11 6.4 11.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIF_alpha PF05793.12 EGB12291.1 - 7.9 4.9 6.6 11 4.4 6.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-PHD-like PF15446.6 EGB12291.1 - 8.9 5.9 13.2 3.7 7.1 1.6 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Ank_4 PF13637.6 EGB12292.1 - 1.6e-16 60.4 0.2 6.1e-09 36.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB12292.1 - 1.1e-14 54.3 2.7 1.8e-05 24.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB12292.1 - 3.9e-14 53.0 0.0 4.7e-07 30.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGB12292.1 - 7.1e-10 38.9 7.8 0.0029 18.0 0.4 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EGB12292.1 - 3e-09 36.4 0.8 0.024 15.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat GST_C_3 PF14497.6 EGB12293.1 - 5.8e-09 36.0 0.0 8.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB12293.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB12293.1 - 0.017 15.4 0.1 0.041 14.2 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB12293.1 - 0.096 12.7 0.3 0.22 11.6 0.3 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UbiA PF01040.18 EGB12294.1 - 8.2e-34 117.0 27.1 1.6e-33 116.1 26.9 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family MORN PF02493.20 EGB12295.1 - 3.5e-40 133.5 80.6 2.4e-05 24.0 0.4 14.8 14 2 0 14 14 14 13 MORN repeat DUF525 PF04379.14 EGB12296.1 - 1.3e-25 89.4 0.0 1.6e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 ApaG domain CorA PF01544.18 EGB12297.1 - 3.7e-41 141.3 0.0 4.5e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HhH-GPD PF00730.25 EGB12298.1 - 2.4e-10 40.8 0.0 3.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NADH-G_4Fe-4S_3 PF10588.9 EGB12298.1 - 0.026 14.0 0.5 0.068 12.7 0.5 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Sigma70_r2 PF04542.14 EGB12299.1 - 7e-19 67.4 1.1 8.8e-19 67.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 EGB12299.1 - 1.8e-09 37.6 0.1 3.6e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 EGB12299.1 - 5.7e-09 35.4 0.0 1.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 DUF4763 PF15960.5 EGB12299.1 - 0.044 13.1 0.1 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Ank_2 PF12796.7 EGB12300.1 - 3.7e-83 274.2 23.6 9.4e-09 35.7 0.3 17.8 9 4 5 15 15 15 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB12300.1 - 2.3e-53 177.9 55.8 0.00012 22.6 0.1 20.6 15 5 7 23 23 23 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12300.1 - 4e-37 122.0 65.7 0.14 12.8 0.1 29.4 33 0 0 33 33 33 13 Ankyrin repeat Ank_5 PF13857.6 EGB12300.1 - 1.4e-32 111.3 89.0 7.8e-08 32.4 0.9 24.1 18 4 7 25 25 25 13 Ankyrin repeats (many copies) Ank PF00023.30 EGB12300.1 - 8.1e-21 73.5 99.2 0.028 14.9 0.5 24.1 25 0 0 25 25 25 12 Ankyrin repeat Arf PF00025.21 EGB12301.1 - 1.8e-68 229.4 0.0 2e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGB12301.1 - 4.5e-13 49.5 0.0 6.3e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGB12301.1 - 1.1e-12 47.8 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGB12301.1 - 2e-11 43.7 0.0 2.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGB12301.1 - 1.1e-08 34.6 0.1 1.9e-06 27.3 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGB12301.1 - 1e-06 28.3 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGB12301.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGB12301.1 - 0.038 13.3 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase WD40 PF00400.32 EGB12302.1 - 2e-32 110.7 32.1 4.3e-05 24.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12302.1 - 2.5e-10 40.5 0.6 0.25 11.7 0.0 4.5 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB12302.1 - 0.0076 15.3 0.7 1.2 8.0 0.0 3.6 4 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB12302.1 - 0.032 14.1 0.0 19 5.1 0.0 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGB12302.1 - 0.044 11.8 0.6 2.3 6.1 0.0 2.5 3 0 0 3 3 3 0 IKI3 family Flavodoxin_1 PF00258.25 EGB12303.1 - 2.5e-24 86.1 0.0 8.9e-24 84.3 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 EGB12303.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Flavodoxin domain Flavodoxin_5 PF12724.7 EGB12303.1 - 0.2 11.9 0.0 0.65 10.2 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain NAD_binding_1 PF00175.21 EGB12304.1 - 1.3e-06 29.0 0.1 1.8e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Pneumo_NS1 PF03438.13 EGB12304.1 - 0.16 12.1 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Pneumovirus NS1 protein HSP70 PF00012.20 EGB12305.1 - 9.7e-28 96.7 0.4 1e-27 96.6 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGB12305.1 - 9.1e-07 28.0 0.0 9.8e-07 27.9 0.0 1.0 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 EGB12305.1 - 0.012 14.6 1.1 0.014 14.4 1.1 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Ppx-GppA PF02541.16 EGB12305.1 - 0.11 11.9 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Ppx/GppA phosphatase family 2-Hacid_dh_C PF02826.19 EGB12306.1 - 3.9e-43 146.9 0.0 5.4e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGB12306.1 - 1.1e-08 34.9 0.1 1.5e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 EGB12306.1 - 0.0023 18.4 0.1 0.0062 17.0 0.1 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 EGB12306.1 - 0.024 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 EGB12306.1 - 0.051 14.0 0.3 1.9 9.0 0.3 2.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Formyl_trans_N PF00551.19 EGB12307.1 - 2.5e-36 125.1 0.0 3e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EGB12307.1 - 3.2e-14 53.0 0.0 4.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Ion_trans_2 PF07885.16 EGB12308.1 - 7.4e-16 57.9 4.2 7.6e-16 57.9 4.2 1.0 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB12308.1 - 1.1e-10 41.1 2.5 1.3e-10 41.0 2.5 1.0 1 0 0 1 1 1 1 Ion transport protein DUF3490 PF11995.8 EGB12309.1 - 0.058 13.2 0.7 0.11 12.3 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Trypan_PARP PF05887.11 EGB12309.1 - 0.13 12.3 27.7 0.024 14.6 23.4 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CdvA PF18822.1 EGB12309.1 - 0.75 9.6 5.8 6.7 6.6 0.4 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain SPESP1 PF15754.5 EGB12309.1 - 1.1 8.4 2.6 1.7 7.7 2.6 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 AOX PF01786.17 EGB12310.1 - 1e-26 93.9 0.0 1.3e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Alternative oxidase Ank_4 PF13637.6 EGB12311.1 - 1.9e-30 104.8 1.7 1.6e-08 34.9 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB12311.1 - 2.7e-27 95.2 0.0 4.8e-14 52.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGB12311.1 - 8.1e-25 84.2 0.8 0.00015 21.9 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EGB12311.1 - 4.2e-23 80.7 4.2 0.00022 21.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EGB12311.1 - 1.4e-20 73.1 3.6 2.2e-09 37.4 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) T3SS_needle_F PF09392.10 EGB12311.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF PALP PF00291.25 EGB12312.1 - 1.9e-68 231.0 2.9 2.9e-68 230.4 2.9 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.32 EGB12313.1 - 4.9e-57 188.6 16.7 1.3e-07 32.2 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12313.1 - 1.3e-21 76.7 0.1 0.004 17.4 0.0 6.3 1 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB12313.1 - 1.2e-08 34.3 7.3 0.13 11.2 0.1 6.0 1 1 6 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGB12313.1 - 0.0028 17.5 0.1 5.3 6.9 0.0 3.9 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGB12313.1 - 0.0074 15.0 0.1 0.026 13.2 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGB12313.1 - 0.078 11.5 2.4 0.96 7.9 0.1 3.0 1 1 0 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 EGB12313.1 - 3 8.4 22.8 12 6.5 0.1 6.1 5 2 0 5 5 5 0 PQQ-like domain WD40 PF00400.32 EGB12314.1 - 3.8e-44 147.8 8.6 4.8e-09 36.7 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12314.1 - 3e-13 49.9 0.0 0.0013 19.0 0.0 3.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB12314.1 - 9.3e-08 31.4 0.1 0.054 12.4 0.0 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGB12314.1 - 0.011 14.5 3.0 0.77 8.3 0.0 3.6 2 2 2 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EGB12314.1 - 0.041 13.2 0.0 7.6 5.8 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain Peptidase_S8 PF00082.22 EGB12315.1 - 2.7e-25 89.3 9.0 5.4e-14 52.2 0.2 3.0 1 1 0 2 2 2 2 Subtilase family P_proprotein PF01483.20 EGB12315.1 - 3.5e-09 36.6 0.1 1e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Proprotein convertase P-domain Kringle PF00051.18 EGB12315.1 - 6.6e-09 36.0 6.7 9.3e-07 29.1 0.7 3.6 3 0 0 3 3 3 2 Kringle domain PRCC PF10253.9 EGB12315.1 - 1.2 9.9 8.2 2.3 8.9 8.2 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FGE-sulfatase PF03781.16 EGB12316.1 - 2.1e-24 86.5 0.0 3.7e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 MFS_1 PF07690.16 EGB12316.1 - 4.4e-19 68.6 36.6 4.4e-19 68.6 36.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGB12316.1 - 1.1e-11 44.3 18.1 6.1e-08 32.0 1.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Methyltransf_23 PF13489.6 EGB12316.1 - 3.3e-09 36.8 0.0 6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB12316.1 - 7.8e-09 36.1 0.5 2.6e-08 34.4 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB12316.1 - 7.9e-09 36.1 0.3 2.7e-07 31.2 0.3 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB12316.1 - 1.5e-08 34.6 0.0 0.0015 18.3 0.3 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGB12316.1 - 1.9e-08 34.9 0.1 8.8e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 EGB12316.1 - 1.8e-07 31.7 1.1 4.8e-07 30.3 0.2 2.3 2 0 0 2 2 2 1 DinB superfamily VCBS PF13517.6 EGB12317.1 - 4.7e-41 139.2 74.4 2.5e-09 37.6 7.0 8.3 4 2 0 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB12317.1 - 3.9e-18 65.2 131.2 0.00021 21.3 3.6 12.6 11 1 0 11 11 11 10 FG-GAP repeat BBS2_Mid PF14783.6 EGB12317.1 - 0.00039 20.4 0.6 5.3 7.1 0.0 5.4 7 0 0 7 7 7 1 Ciliary BBSome complex subunit 2, middle region DUF2141 PF09912.9 EGB12317.1 - 0.11 12.4 7.0 60 3.6 0.0 5.4 5 1 1 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2141) Ephrin_rec_like PF07699.13 EGB12317.1 - 2.9 7.7 29.0 0.3 10.9 6.0 4.9 4 1 1 5 5 5 0 Putative ephrin-receptor like Laminin_EGF PF00053.24 EGB12317.1 - 4.5 7.5 57.1 0.069 13.3 13.8 4.8 4 0 0 4 4 4 0 Laminin EGF domain EGF PF00008.27 EGB12317.1 - 5.8 7.3 19.7 0.61 10.4 5.7 3.3 3 0 0 3 3 3 0 EGF-like domain Cupin_4 PF08007.12 EGB12318.1 - 4.6e-20 72.3 0.0 7.2e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EGB12318.1 - 4.7e-05 23.2 0.0 0.00073 19.3 0.0 2.0 2 0 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 EGB12318.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Cupin domain DUF4232 PF14016.6 EGB12318.1 - 0.11 12.6 3.1 2 8.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4232) Cupin_3 PF05899.12 EGB12318.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Ank_4 PF13637.6 EGB12319.1 - 5.6e-18 65.1 1.3 4.1e-07 30.4 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB12319.1 - 8.3e-15 54.5 3.8 2.7e-09 37.0 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGB12319.1 - 1.1e-13 51.1 0.8 4.1e-12 46.1 0.2 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12319.1 - 1.3e-12 46.7 0.9 6.9e-06 26.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EGB12319.1 - 1.7e-12 47.8 0.1 2.4e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Gln-synt_C PF00120.24 EGB12320.1 - 8.1e-19 67.8 0.0 1.2e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGB12320.1 - 2.8e-09 36.6 0.0 5.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Aminotran_1_2 PF00155.21 EGB12321.1 - 5.6e-14 52.1 0.0 7.7e-07 28.6 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Ribosomal_S30AE PF02482.19 EGB12322.1 - 6.2e-20 71.8 0.4 9.4e-20 71.2 0.4 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 EGB12322.1 - 8.8e-14 50.9 0.1 1.6e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Cellulose_synt PF03552.14 EGB12322.1 - 0.14 10.6 0.1 0.16 10.5 0.1 1.1 1 0 0 1 1 1 0 Cellulose synthase AAA PF00004.29 EGB12323.1 - 6.9e-33 113.9 0.0 8.8e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB12323.1 - 1.8e-09 37.3 0.0 3.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGB12323.1 - 2.7e-06 27.9 0.1 8e-05 23.1 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGB12323.1 - 1.1e-05 25.5 0.2 0.0017 18.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 EGB12323.1 - 0.0003 20.9 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 EGB12323.1 - 0.00049 20.4 0.1 0.02 15.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 EGB12323.1 - 0.00058 19.3 0.0 3.4 7.0 0.0 3.2 1 1 2 3 3 3 2 Bacterial TniB protein RuvB_N PF05496.12 EGB12323.1 - 0.00067 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EGB12323.1 - 0.001 18.8 0.1 0.0056 16.4 0.0 2.1 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 EGB12323.1 - 0.0035 17.5 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGB12323.1 - 0.0039 16.5 0.0 0.012 14.8 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain TsaE PF02367.17 EGB12323.1 - 0.0063 16.5 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGB12323.1 - 0.024 15.2 0.0 0.032 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGB12323.1 - 0.032 14.6 0.0 0.091 13.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.6 EGB12323.1 - 0.035 13.8 0.0 0.069 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGB12323.1 - 0.044 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGB12323.1 - 0.048 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGB12323.1 - 0.059 12.7 0.2 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EGB12323.1 - 0.16 11.2 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EGB12323.1 - 0.2 11.6 0.1 0.42 10.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 EGB12323.1 - 0.2 11.0 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 EGB12323.1 - 0.23 10.7 0.1 0.4 9.9 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin CAF1A PF12253.8 EGB12324.1 - 1.2e-11 44.6 3.1 1.2e-11 44.6 3.1 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A ATP-grasp_3 PF02655.14 EGB12324.1 - 0.00018 21.6 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGB12324.1 - 0.00022 20.8 0.1 0.0051 16.3 0.1 2.3 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 EGB12324.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EGB12324.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TFIIA PF03153.13 EGB12324.1 - 0.81 9.6 17.9 0.2 11.6 9.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 EGB12324.1 - 1.3 7.7 3.5 2.2 7.0 3.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase PF00069.25 EGB12325.1 - 2.8e-47 161.3 0.0 3.3e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12325.1 - 2e-21 76.4 0.0 2.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB12325.1 - 0.022 14.7 0.2 0.039 13.9 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB12325.1 - 0.073 12.4 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Abhydrolase_2 PF02230.16 EGB12326.1 - 1.2e-43 149.4 0.0 1.5e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGB12326.1 - 4.9e-07 30.6 7.8 7.9e-07 29.9 7.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EGB12326.1 - 2.9e-06 27.1 0.1 2.9e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 EGB12326.1 - 3.8e-06 26.6 0.0 6.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EGB12326.1 - 1e-05 24.9 0.0 0.0001 21.7 0.0 2.2 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGB12326.1 - 1.2e-05 24.9 0.2 0.024 14.1 0.2 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGB12326.1 - 1.4e-05 24.9 0.1 4.3e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGB12326.1 - 0.00016 21.6 0.1 0.00023 21.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGB12326.1 - 0.0033 17.1 0.0 0.0062 16.2 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 EGB12326.1 - 0.0043 17.0 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Cutinase AXE1 PF05448.12 EGB12326.1 - 0.014 14.1 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 EGB12326.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S28 PF05577.12 EGB12326.1 - 0.062 12.1 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF2920 PF11144.8 EGB12326.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF2974 PF11187.8 EGB12326.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LVIVD PF08309.11 EGB12327.1 - 0.00012 21.3 1.7 3.2 7.2 0.0 5.4 6 0 0 6 6 6 2 LVIVD repeat Arylesterase PF01731.20 EGB12327.1 - 0.00051 20.2 0.0 0.73 10.1 0.0 4.0 4 0 0 4 4 4 1 Arylesterase Lactonase PF10282.9 EGB12327.1 - 0.0016 17.8 0.5 0.22 10.8 0.0 3.0 2 2 1 3 3 3 1 Lactonase, 7-bladed beta-propeller Chorion_2 PF03964.15 EGB12327.1 - 0.16 12.8 0.9 18 6.2 0.1 2.8 1 1 1 2 2 2 0 Chorion family 2 Asp PF00026.23 EGB12328.1 - 9.1e-51 173.1 0.0 1e-50 173.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGB12328.1 - 1.9e-11 44.5 0.2 1.2e-07 32.2 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Glyco_transf_25 PF01755.17 EGB12329.1 - 3.4e-10 40.1 0.0 1.1e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF4384 PF14326.6 EGB12330.1 - 0.11 12.7 0.9 0.19 11.9 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) EF-hand_7 PF13499.6 EGB12332.1 - 1e-11 45.1 0.1 4.2e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB12332.1 - 1e-09 37.5 0.6 0.084 12.8 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGB12332.1 - 7.2e-09 34.6 0.7 0.034 13.7 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 EGB12332.1 - 0.00069 19.0 1.4 0.32 10.6 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EGB12332.1 - 0.0052 16.6 2.3 5.6 6.9 0.1 3.3 2 1 1 3 3 3 1 EF-hand domain pair EspA PF03433.13 EGB12332.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.2 1 1 0 1 1 1 0 EspA-like secreted protein PDEase_I PF00233.19 EGB12333.1 - 3.7e-68 229.8 0.0 4.4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Rad60-SLD PF11976.8 EGB12334.1 - 3.7e-19 68.3 0.2 4.8e-19 68.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGB12334.1 - 6.3e-10 38.7 0.0 8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SH3_3 PF08239.11 EGB12335.1 - 5e-06 26.7 0.1 0.0066 16.7 0.0 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain Glycos_transf_2 PF00535.26 EGB12335.1 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF1713 PF08213.11 EGB12335.1 - 0.0017 18.3 18.1 0.0033 17.3 18.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) SNF2_N PF00176.23 EGB12336.1 - 8.4e-46 156.3 0.0 1.2e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain GMC_oxred_N PF00732.19 EGB12336.1 - 2.9e-22 79.4 0.0 5.3e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase TTL PF03133.15 EGB12336.1 - 1.9e-18 66.6 0.0 5.9e-18 65.0 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family GMC_oxred_C PF05199.13 EGB12336.1 - 4.2e-15 56.5 3.2 4.3e-15 56.5 0.0 2.6 2 0 0 2 2 2 1 GMC oxidoreductase FHA PF00498.26 EGB12336.1 - 3.9e-05 23.9 0.1 7.4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGB12336.1 - 0.00067 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TUDOR_5 PF18359.1 EGB12336.1 - 0.0022 17.7 0.6 0.006 16.2 0.1 1.9 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 NAD_binding_8 PF13450.6 EGB12336.1 - 0.0063 16.7 0.2 0.0063 16.7 0.2 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Helicase_C PF00271.31 EGB12336.1 - 0.054 13.8 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain ATP-grasp_3 PF02655.14 EGB12336.1 - 0.068 13.2 0.0 23 5.0 0.0 2.8 3 0 0 3 3 3 0 ATP-grasp domain ATPgrasp_YheCD PF14398.6 EGB12336.1 - 0.11 11.7 0.0 8 5.6 0.0 2.6 2 1 0 2 2 2 0 YheC/D like ATP-grasp zf-RING_5 PF14634.6 EGB12336.1 - 0.76 9.8 7.2 0.59 10.1 5.0 2.0 2 0 0 2 2 2 0 zinc-RING finger domain RSN1_7TM PF02714.15 EGB12337.1 - 7.8e-32 110.7 19.8 9.2e-32 110.4 19.8 1.0 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Na_Ca_ex PF01699.24 EGB12338.1 - 3e-20 72.7 14.6 4.5e-20 72.2 14.6 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF1336 PF07059.12 EGB12339.1 - 1.9e-56 191.7 0.0 2.3e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PRP38 PF03371.15 EGB12340.1 - 1.3e-57 194.4 0.2 1.6e-57 194.2 0.2 1.1 1 0 0 1 1 1 1 PRP38 family RPA43_OB PF17875.1 EGB12340.1 - 0.0054 17.4 0.0 0.008 16.8 0.0 1.2 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I CDC45 PF02724.14 EGB12340.1 - 6.8 4.9 5.9 8.2 4.6 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Brix PF04427.18 EGB12341.1 - 6.2e-35 121.0 0.0 8.3e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Laminin_G_2 PF02210.24 EGB12342.1 - 0.029 15.0 0.0 0.063 13.9 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain Ion_trans_2 PF07885.16 EGB12343.1 - 1.1e-07 31.8 0.3 1.9e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGB12343.1 - 3.3e-07 30.3 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Big_2 PF02368.18 EGB12343.1 - 0.05 13.5 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Sel1 PF08238.12 EGB12344.1 - 2.6e-09 37.5 0.7 0.00043 20.9 0.1 3.1 2 0 0 2 2 2 2 Sel1 repeat DUF3361 PF11841.8 EGB12344.1 - 0.016 15.2 1.9 0.21 11.5 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) Arm PF00514.23 EGB12344.1 - 0.18 11.9 16.2 28 4.9 0.0 9.7 8 1 0 8 8 8 0 Armadillo/beta-catenin-like repeat AAA_21 PF13304.6 EGB12345.1 - 1e-09 38.7 0.0 1.4e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EGB12345.1 - 1.3e-09 38.7 0.0 1.7e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_tran PF00005.27 EGB12346.1 - 4.8e-27 95.1 0.0 6.1e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB12346.1 - 6.6e-13 49.1 0.1 3e-09 37.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGB12346.1 - 0.00045 20.6 0.1 0.00088 19.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGB12346.1 - 0.026 13.9 0.1 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGB12346.1 - 0.14 11.9 0.0 7.6 6.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Bestrophin PF01062.21 EGB12347.1 - 3.8e-24 85.6 1.2 7.7e-24 84.6 1.2 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1461 PF07314.11 EGB12347.1 - 0.1 12.5 0.4 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) DUF4149 PF13664.6 EGB12347.1 - 0.41 11.0 2.4 12 6.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) UAA PF08449.11 EGB12348.1 - 3.6e-39 134.8 3.4 4e-39 134.6 3.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB12348.1 - 0.0013 18.9 3.6 0.0013 18.9 3.6 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGB12348.1 - 0.24 10.7 4.6 0.51 9.6 4.6 1.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family XRN_N PF03159.18 EGB12349.1 - 2.1e-65 220.5 0.0 2.4e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EGB12350.1 - 7.5e-22 77.9 0.0 8e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Xrn1 helical domain UPRTase PF14681.6 EGB12351.1 - 7.4e-71 237.9 0.0 8.8e-71 237.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGB12351.1 - 2.6e-05 23.8 0.1 4.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Peripla_BP_6 PF13458.6 EGB12351.1 - 0.094 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Sterol-sensing PF12349.8 EGB12352.1 - 1.8e-11 44.1 2.9 2.7e-11 43.6 2.9 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EGB12352.1 - 2.2e-11 42.6 8.1 2.9e-11 42.2 8.1 1.1 1 0 0 1 1 1 1 Patched family MMPL PF03176.15 EGB12352.1 - 0.00027 20.0 18.6 0.0013 17.8 18.6 1.8 1 1 0 1 1 1 1 MMPL family Sel1 PF08238.12 EGB12353.1 - 4.3e-41 138.4 22.6 7.6e-09 36.0 0.2 8.1 8 1 0 8 8 8 5 Sel1 repeat TetR_C_11 PF16859.5 EGB12353.1 - 0.0042 17.4 3.2 19 5.6 0.2 4.3 4 0 0 4 4 4 1 Tetracyclin repressor-like, C-terminal domain TPR_16 PF13432.6 EGB12353.1 - 0.0098 16.5 24.1 0.11 13.2 0.7 5.6 4 2 2 6 6 6 2 Tetratricopeptide repeat MIT PF04212.18 EGB12353.1 - 0.14 12.3 3.7 4.5 7.4 0.1 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain EF-hand_7 PF13499.6 EGB12353.1 - 0.15 12.5 0.0 20 5.7 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain pair B12-binding_2 PF02607.17 EGB12353.1 - 0.17 12.3 1.5 4.9 7.7 0.1 2.9 3 0 0 3 3 3 0 B12 binding domain TPR_12 PF13424.6 EGB12353.1 - 0.26 11.6 20.0 1 9.7 0.1 6.2 3 3 3 6 6 6 0 Tetratricopeptide repeat HEAT PF02985.22 EGB12354.1 - 2.5e-15 55.2 49.6 0.0042 17.2 0.2 15.7 18 0 0 18 18 16 6 HEAT repeat HEAT_EZ PF13513.6 EGB12354.1 - 2.7e-09 37.3 106.8 0.00069 20.1 4.4 16.5 12 3 6 18 18 18 6 HEAT-like repeat HEAT_2 PF13646.6 EGB12354.1 - 1.8e-07 31.4 113.8 0.00067 20.0 4.1 14.0 5 3 7 14 14 14 7 HEAT repeats Cnd1 PF12717.7 EGB12354.1 - 1.9e-05 24.8 0.0 1.4 9.0 0.0 5.4 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EGB12354.1 - 0.00031 20.0 0.1 0.43 9.7 0.0 3.7 3 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 EGB12354.1 - 0.00074 19.1 0.0 0.038 13.5 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal DUF3437 PF11919.8 EGB12354.1 - 0.0042 17.0 0.4 4.3 7.3 0.1 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3437) DUF3535 PF12054.8 EGB12354.1 - 0.076 12.2 0.1 1.9 7.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3535) ParcG PF10274.9 EGB12354.1 - 0.18 11.9 0.0 28 4.8 0.0 3.5 4 0 0 4 4 4 0 Parkin co-regulated protein ADSL_C PF10397.9 EGB12354.1 - 1.2 9.8 12.6 5.5 7.6 1.0 5.1 4 0 0 4 4 4 0 Adenylosuccinate lyase C-terminus Cohesin_HEAT PF12765.7 EGB12354.1 - 2.7 8.4 12.6 0.21 11.9 0.2 4.6 5 0 0 5 5 3 0 HEAT repeat associated with sister chromatid cohesion DnaJ PF00226.31 EGB12355.1 - 4.1e-23 81.3 1.3 4.4e-23 81.2 1.3 1.0 1 0 0 1 1 1 1 DnaJ domain GFO_IDH_MocA PF01408.22 EGB12356.1 - 6.1e-19 69.0 0.0 1e-18 68.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EGB12356.1 - 4.4e-05 24.0 0.0 9.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ribosomal_L27A PF00828.19 EGB12358.1 - 1.4e-31 109.9 0.0 1.6e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AAA_5 PF07728.14 EGB12359.1 - 9.7e-20 71.0 0.0 1.6e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 EGB12359.1 - 1.5e-12 47.2 0.1 4.3e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 AAA lid domain Methyltransf_11 PF08241.12 EGB12359.1 - 2.5e-11 44.1 0.0 9.9e-11 42.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB12359.1 - 1.4e-10 41.2 0.0 3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain VWA_CoxE PF05762.14 EGB12359.1 - 7.4e-08 32.1 1.1 8.5e-07 28.6 0.1 2.6 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EGB12359.1 - 1.7e-07 31.9 0.0 4.4e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Methyltransf_12 PF08242.12 EGB12359.1 - 1.5e-06 28.8 0.0 5.5e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB12359.1 - 8e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB12359.1 - 2.9e-05 24.7 0.0 0.00013 22.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Mg_chelatase PF01078.21 EGB12359.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EGB12359.1 - 0.0062 17.0 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EGB12359.1 - 0.0076 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ubie_methyltran PF01209.18 EGB12359.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AAA_22 PF13401.6 EGB12359.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DREV PF05219.12 EGB12359.1 - 0.26 10.3 0.0 0.46 9.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase AAA_16 PF13191.6 EGB12359.1 - 0.42 11.0 10.4 0.72 10.2 0.0 5.1 5 1 1 6 6 6 0 AAA ATPase domain DUF21 PF01595.20 EGB12362.1 - 3.3e-31 108.3 0.5 5.1e-31 107.7 0.5 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGB12362.1 - 3.1e-08 33.9 0.1 0.00035 21.0 0.1 2.8 1 1 0 2 2 2 2 CBS domain AICARFT_IMPCHas PF01808.18 EGB12363.1 - 5.5e-78 262.4 0.0 7.6e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGB12363.1 - 5.9e-24 84.1 0.0 1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain ATG11 PF10377.9 EGB12364.1 - 5e-16 58.9 0.0 8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 11 APG17 PF04108.12 EGB12364.1 - 1.2e-06 28.0 0.0 2.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein Apg17 PAS_9 PF13426.7 EGB12366.1 - 3.8e-08 33.5 0.0 4.1e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 PAS domain Acetyltransf_2 PF00797.17 EGB12367.1 - 5.5e-28 98.4 0.0 7.9e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase DUF2020 PF09449.10 EGB12367.1 - 0.83 9.5 4.0 8.4 6.2 0.1 3.7 3 1 2 5 5 5 0 Domain of unknown function (DUF2020) DUF987 PF06174.11 EGB12367.1 - 1.2 9.1 3.6 20 5.2 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF987) AMP-binding PF00501.28 EGB12369.1 - 1.7e-185 616.7 0.0 3.8e-66 223.4 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGB12369.1 - 4.8e-110 368.3 0.0 1.8e-43 148.9 0.0 6.1 6 0 0 6 6 6 5 Condensation domain NAD_binding_4 PF07993.12 EGB12369.1 - 3.7e-48 164.0 0.0 5.3e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.6 EGB12369.1 - 6.4e-32 110.4 9.2 1.7e-10 41.7 0.0 4.6 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EGB12369.1 - 8.6e-30 102.9 2.5 6.1e-13 48.9 0.1 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site Epimerase PF01370.21 EGB12369.1 - 1.1e-14 54.5 0.0 2.8e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB12369.1 - 0.00012 21.2 0.0 0.00048 19.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGB12369.1 - 0.004 16.3 0.0 2.1 7.4 0.0 2.6 2 0 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGB12369.1 - 0.0063 16.0 0.0 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase PH PF00169.29 EGB12369.1 - 0.008 16.7 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 PH domain DUF5075 PF16825.5 EGB12369.1 - 0.18 11.5 0.5 8 6.1 0.1 2.4 2 0 0 2 2 2 0 IGP family C-type lectin domain PSK_trans_fac PF07704.11 EGB12369.1 - 3.5 8.5 9.0 0.83 10.5 1.2 4.4 3 0 0 3 3 3 0 Rv0623-like transcription factor Arm PF00514.23 EGB12370.1 - 5.6e-38 127.8 10.1 3.6e-09 36.3 0.2 5.0 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGB12370.1 - 1.7e-07 30.9 6.5 0.18 12.1 0.0 4.4 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 EGB12370.1 - 1.3e-05 25.4 15.9 0.00014 22.2 6.6 3.1 1 1 2 3 3 3 3 HEAT repeats HEAT_EZ PF13513.6 EGB12370.1 - 1.5e-05 25.4 9.7 0.41 11.2 1.0 4.2 3 1 1 4 4 4 3 HEAT-like repeat RICTOR_N PF14664.6 EGB12370.1 - 1.8e-05 23.9 0.0 0.91 8.4 0.0 3.2 2 2 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term Aconitase_B_N PF11791.8 EGB12370.1 - 0.00025 21.1 1.2 7 6.7 0.0 3.4 1 1 2 3 3 3 3 Aconitate B N-terminal domain Arm_2 PF04826.13 EGB12370.1 - 0.0016 17.9 0.0 4.4 6.7 0.0 2.9 1 1 3 4 4 4 1 Armadillo-like N1221 PF07923.13 EGB12370.1 - 0.0016 17.7 0.0 5.1 6.2 0.0 3.4 1 1 3 4 4 4 1 N1221-like protein Cnd1 PF12717.7 EGB12370.1 - 0.017 15.2 0.0 1.7 8.6 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 EGB12370.1 - 0.18 12.2 0.0 52 4.3 0.0 3.0 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_PBS PF03130.16 EGB12370.1 - 0.71 10.7 20.0 4.3 8.3 2.7 5.0 3 3 1 4 4 4 0 PBS lyase HEAT-like repeat ALF PF03752.13 EGB12370.1 - 2.6 8.1 17.1 1.2 9.2 0.5 4.5 4 0 0 4 4 4 0 Short repeats of unknown function Peptidase_C2 PF00648.21 EGB12371.1 - 1.4e-28 99.8 0.0 1.6e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease DUF5011 PF16403.5 EGB12372.1 - 3.9e-07 30.1 0.1 0.022 14.9 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF5011) EGF_3 PF12947.7 EGB12372.1 - 5.6e-06 26.5 4.9 5.6e-06 26.5 4.9 4.3 4 0 0 4 4 4 2 EGF domain EGF_CA PF07645.15 EGB12372.1 - 2.9e-05 24.2 15.0 0.0001 22.4 6.3 6.8 5 3 1 6 6 6 3 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 EGB12372.1 - 0.012 15.9 0.6 0.012 15.9 0.6 3.1 5 0 0 5 5 5 0 Pvs28 EGF domain Lipase_3 PF01764.25 EGB12373.1 - 2e-26 92.6 0.0 3.1e-24 85.5 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) DUF2974 PF11187.8 EGB12373.1 - 0.03 13.9 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) vATP-synt_AC39 PF01992.16 EGB12374.1 - 1.2e-108 363.6 0.1 1.3e-108 363.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Myosin_head PF00063.21 EGB12375.1 - 4.2e-196 653.2 0.0 5.5e-196 652.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGB12375.1 - 0.052 13.9 0.0 0.052 13.9 0.0 4.7 4 1 0 4 4 4 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EGB12375.1 - 0.16 11.5 0.0 5.5 6.5 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TsaE PF02367.17 EGB12375.1 - 0.39 10.7 1.1 0.82 9.7 0.2 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AKNA PF12443.8 EGB12376.1 - 0.48 11.1 2.3 29 5.4 0.1 2.9 2 0 0 2 2 2 0 AT-hook-containing transcription factor Na_H_Exchanger PF00999.21 EGB12377.1 - 2.5e-11 43.0 5.0 2.6e-11 42.9 5.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 EGB12378.1 - 1.1e-23 83.7 14.7 1.7e-23 83.1 14.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EGB12378.1 - 1.4e-23 83.4 0.0 2.7e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AdoHcyase_NAD PF00670.21 EGB12378.1 - 0.00084 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PK_C PF02887.16 EGB12378.1 - 0.011 15.9 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Helicase_C PF00271.31 EGB12379.1 - 3.8e-12 46.5 0.0 6.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FKBP_C PF00254.28 EGB12380.1 - 4.3e-17 62.2 0.0 5.5e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Aldedh PF00171.22 EGB12381.1 - 4.2e-33 114.5 0.0 7.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FHA PF00498.26 EGB12382.1 - 8.1e-10 38.9 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGB12382.1 - 0.00028 21.1 0.0 0.00081 19.7 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain adh_short_C2 PF13561.6 EGB12383.1 - 4e-50 170.6 2.1 1.9e-46 158.5 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB12383.1 - 4.4e-12 45.9 1.3 2.8e-09 36.7 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.8 EGB12383.1 - 0.0012 18.3 0.2 0.4 10.0 0.0 2.2 2 0 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region Neur_chan_LBD PF02931.23 EGB12384.1 - 2.1e-14 53.5 0.0 3.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain PGAP1 PF07819.13 EGB12384.1 - 2.6e-06 27.4 0.0 5.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EGB12384.1 - 0.00051 20.0 0.0 0.00092 19.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGB12384.1 - 0.0078 15.9 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold TUDOR_5 PF18359.1 EGB12384.1 - 0.011 15.4 0.4 0.027 14.2 0.4 1.7 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Hydrolase_4 PF12146.8 EGB12384.1 - 0.032 13.5 0.5 0.27 10.5 0.0 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Agenet PF05641.12 EGB12384.1 - 0.043 14.3 0.4 0.15 12.5 0.1 2.2 2 0 0 2 2 2 0 Agenet domain LBR_tudor PF09465.10 EGB12384.1 - 0.15 11.9 0.2 0.39 10.6 0.2 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain CFAP91 PF14738.6 EGB12385.1 - 1.4e-50 171.3 10.0 1.4e-50 171.3 10.0 2.1 3 0 0 3 3 3 1 Cilia- and flagella-associated protein 91 AI-2E_transport PF01594.16 EGB12386.1 - 6.9e-14 51.7 7.0 7.2e-14 51.7 7.0 1.0 1 0 0 1 1 1 1 AI-2E family transporter Topoisom_bac PF01131.20 EGB12387.1 - 2.3e-96 323.4 0.0 2.7e-96 323.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGB12387.1 - 3e-14 53.1 0.0 5.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Myosin_head PF00063.21 EGB12388.1 - 1.7e-42 145.5 0.0 2.6e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.18 EGB12388.1 - 1.4e-38 131.3 16.5 2.4e-09 37.7 1.0 7.7 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGB12388.1 - 5e-32 109.0 32.6 4.5e-07 29.5 3.0 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat AAA_16 PF13191.6 EGB12388.1 - 3.4 8.0 6.9 1.6 9.1 0.0 3.9 3 0 0 3 3 3 0 AAA ATPase domain SWIB PF02201.18 EGB12389.1 - 2.2e-21 75.5 0.0 3.9e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain SlyX PF04102.12 EGB12389.1 - 0.054 14.1 0.2 0.45 11.2 0.0 2.6 2 0 0 2 2 2 0 SlyX MBD PF01429.19 EGB12389.1 - 0.073 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyl-CpG binding domain BRCT PF00533.26 EGB12389.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ADD_DNMT3 PF17980.1 EGB12389.1 - 0.23 11.5 2.0 0.63 10.1 2.0 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Lar_restr_allev PF14354.6 EGB12389.1 - 0.42 11.0 10.0 4.2 7.8 1.7 4.1 3 0 0 3 3 3 0 Restriction alleviation protein Lar RNA_pol PF00940.19 EGB12390.1 - 1.9e-155 517.8 0.0 4.5e-155 516.6 0.0 1.6 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGB12390.1 - 2.1e-61 208.2 0.0 2.8e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Lactamase_B_2 PF12706.7 EGB12391.1 - 2.1e-12 47.0 0.6 1.6e-06 27.8 0.0 2.6 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGB12391.1 - 1.1e-11 45.2 0.1 1.4e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily baeRF_family2 PF18844.1 EGB12391.1 - 0.00015 21.8 0.1 0.00028 21.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 Lactamase_B_4 PF13691.6 EGB12391.1 - 0.0027 17.3 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease ATP-synt PF00231.19 EGB12392.1 - 7.2e-83 278.5 0.0 8.7e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase PWWP PF00855.17 EGB12393.1 - 1.5e-09 38.1 0.4 1.5e-09 38.1 0.4 2.3 2 0 0 2 2 2 1 PWWP domain Docking PF08990.11 EGB12394.1 - 0.13 11.9 2.4 0.26 10.9 2.4 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking CAP_N PF01213.19 EGB12394.1 - 1.7 8.1 4.5 2.9 7.3 4.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AMP-binding PF00501.28 EGB12395.1 - 5.5e-48 163.6 0.3 6.6e-48 163.3 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB12395.1 - 5.6e-16 59.3 0.7 9.8e-16 58.5 0.7 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peripla_BP_5 PF13433.6 EGB12395.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain ketoacyl-synt PF00109.26 EGB12396.1 - 9.5e-47 159.7 3.9 1.3e-46 159.3 3.9 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB12396.1 - 1.2e-10 41.5 0.2 3.2e-10 40.0 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB12396.1 - 0.023 14.1 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Herpes_UL43 PF05072.13 EGB12396.1 - 0.024 13.8 0.5 0.13 11.3 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus UL43 protein Sulfotransfer_2 PF03567.14 EGB12397.1 - 1.7e-07 31.4 0.0 2.5e-06 27.6 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase family Synaptobrevin PF00957.21 EGB12398.1 - 4e-28 97.1 0.3 6.2e-28 96.4 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGB12398.1 - 2.9e-23 81.7 0.1 4.8e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.8 EGB12398.1 - 0.1 13.6 0.2 0.31 12.1 0.1 1.8 2 0 0 2 2 2 0 SpoIIAA-like Mal_decarbox_Al PF16957.5 EGB12398.1 - 0.13 10.6 0.0 0.25 9.6 0.0 1.4 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter adh_short PF00106.25 EGB12399.1 - 5.8e-46 156.4 7.9 7.2e-46 156.1 7.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB12399.1 - 1.6e-34 119.5 8.3 2e-34 119.1 8.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB12399.1 - 7.7e-16 58.5 3.9 1.1e-15 58.0 3.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB12399.1 - 3.5e-09 36.5 2.3 4.1e-09 36.3 0.7 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 EGB12399.1 - 0.00018 21.4 1.9 0.00018 21.4 1.9 1.6 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.8 EGB12399.1 - 0.028 14.2 0.8 0.06 13.1 0.8 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.17 EGB12399.1 - 0.056 12.5 1.3 0.077 12.1 1.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 EGB12399.1 - 0.11 11.9 1.0 0.18 11.1 0.5 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGB12399.1 - 0.52 10.2 9.9 1 9.2 9.9 1.7 1 1 0 1 1 1 0 NAD(P)H-binding ADH_zinc_N PF00107.26 EGB12399.1 - 2.2 8.3 11.2 0.42 10.6 5.4 2.4 2 1 1 3 3 3 0 Zinc-binding dehydrogenase cNMP_binding PF00027.29 EGB12400.1 - 9.9e-17 60.8 2.2 0.00032 20.7 0.0 5.3 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_2 PF13532.6 EGB12400.1 - 1.3e-10 41.8 0.0 2.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily C2 PF00168.30 EGB12400.1 - 2e-10 40.9 0.0 6.6e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 C2 domain TFCD_C PF12612.8 EGB12400.1 - 0.71 9.7 10.0 3.6 7.4 1.8 2.5 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal Phasin_2 PF09361.10 EGB12400.1 - 2.6 8.4 11.4 10 6.5 2.1 3.0 2 0 0 2 2 2 0 Phasin protein DEAD PF00270.29 EGB12401.1 - 8.6e-25 87.5 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB12401.1 - 0.00011 22.3 0.0 0.00014 22.0 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CLPTM1 PF05602.12 EGB12402.1 - 0.0015 17.7 0.2 0.002 17.3 0.2 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EGB12402.1 - 0.011 15.4 0.4 0.025 14.3 0.4 1.7 1 1 0 1 1 1 0 PQ loop repeat Fer4 PF00037.27 EGB12403.1 - 6.8e-15 54.2 17.8 9.8e-09 34.7 5.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGB12403.1 - 4e-13 49.7 11.6 7.5e-13 48.9 11.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGB12403.1 - 1.4e-11 45.1 9.4 6.9e-06 26.9 0.3 2.8 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EGB12403.1 - 1.1e-10 41.5 22.4 1.2e-07 31.7 13.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EGB12403.1 - 2.6e-10 40.3 4.4 6.8e-05 22.9 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGB12403.1 - 2.5e-09 37.2 9.7 5e-09 36.2 9.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGB12403.1 - 1.1e-07 32.1 20.6 2.9e-05 24.4 12.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGB12403.1 - 1.9e-07 30.9 18.1 0.0002 21.3 5.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EGB12403.1 - 2.8e-07 30.2 12.9 0.0027 17.7 3.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGB12403.1 - 3.5e-05 24.0 11.5 0.00064 20.0 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGB12403.1 - 7.3e-05 23.2 12.4 0.0087 16.6 13.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EGB12403.1 - 0.0028 17.8 6.6 0.51 10.6 0.6 2.7 2 1 1 3 3 3 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EGB12403.1 - 0.006 16.8 9.0 0.4 10.9 1.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EGB12403.1 - 0.017 16.0 17.6 0.09 13.8 4.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 EGB12403.1 - 0.037 14.6 19.9 0.44 11.1 2.9 3.6 3 1 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 EGB12403.1 - 0.25 11.5 6.4 1.4 9.1 0.7 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 EGB12403.1 - 0.31 11.9 12.4 1.6 9.7 1.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain 2Fe-2S_Ferredox PF11591.8 EGB12403.1 - 0.52 10.2 7.3 0.93 9.4 7.3 1.4 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide PhzC-PhzF PF02567.16 EGB12404.1 - 1.4e-51 175.7 0.0 1.7e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 EGB12404.1 - 0.00029 21.1 0.1 0.0006 20.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGB12404.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HAD_SAK_2 PF18143.1 EGB12405.1 - 3.9e-05 24.0 0.0 6.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins DUF4347 PF14252.6 EGB12406.1 - 1.5e-26 93.2 0.2 2.4e-26 92.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) LRR_6 PF13516.6 EGB12406.1 - 0.00052 19.9 0.0 0.27 11.4 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeat PSI PF01437.25 EGB12407.1 - 0.097 13.2 4.0 0.28 11.8 4.0 1.8 1 0 0 1 1 1 0 Plexin repeat LRR_6 PF13516.6 EGB12408.1 - 3.1e-16 58.0 0.7 0.0043 17.0 0.0 7.4 8 0 0 8 8 8 5 Leucine Rich repeat Ribosomal_L17 PF01196.19 EGB12409.1 - 9.5e-33 113.0 0.1 1.2e-32 112.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 RRM_1 PF00076.22 EGB12410.1 - 2.3e-11 43.3 0.0 2.6e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGB12410.1 - 0.00044 19.8 0.0 0.00051 19.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB12410.1 - 0.05 13.7 0.0 0.099 12.8 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 EGB12410.1 - 0.099 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif EF-hand_1 PF00036.32 EGB12411.1 - 1.6e-06 27.3 0.7 2.4e-06 26.7 0.7 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGB12411.1 - 6.3e-05 22.6 0.2 0.00011 21.8 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EGB12411.1 - 0.00014 21.1 0.9 0.00024 20.4 0.9 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGB12411.1 - 0.00064 20.1 0.6 0.0011 19.3 0.6 1.3 1 0 0 1 1 1 1 EF-hand domain pair DUF2721 PF11026.8 EGB12411.1 - 0.046 13.6 0.2 0.089 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2371 PF10177.9 EGB12411.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Nucleoside_tran PF01733.18 EGB12411.1 - 0.21 10.9 0.3 0.33 10.3 0.1 1.3 1 1 0 1 1 1 0 Nucleoside transporter rRNA_proc-arch PF13234.6 EGB12411.1 - 0.27 11.1 2.0 0.43 10.5 2.0 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain Ribosomal_S7e PF01251.18 EGB12412.1 - 9.3e-84 279.8 0.5 1.2e-83 279.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e DUF3546 PF12066.8 EGB12413.1 - 1.8e-14 53.9 0.2 4.1e-14 52.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EGB12413.1 - 0.0031 17.9 0.3 0.0073 16.7 0.0 1.9 2 0 0 2 2 2 1 Arsenite-resistance protein 2 Glyco_hydro2_C5 PF18565.1 EGB12414.1 - 2.4e-16 59.4 0.9 7.3e-16 57.9 0.9 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 EGB12414.1 - 3e-16 59.4 0.0 4.9e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 EGB12414.1 - 8.1e-11 41.7 0.2 1.9e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 EGB12414.1 - 1.9e-08 34.4 0.0 3.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain YHYH PF14240.6 EGB12414.1 - 3.2e-07 30.5 4.6 3.3e-06 27.2 4.4 2.6 1 1 0 1 1 1 1 YHYH protein Glyco_hydro_2 PF00703.21 EGB12414.1 - 4.1e-06 27.4 0.0 8.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 ACT PF01842.25 EGB12414.1 - 0.0063 16.3 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 ACT domain Sel1 PF08238.12 EGB12415.1 - 3.8e-52 173.6 19.8 2.7e-10 40.6 0.1 6.6 7 0 0 7 7 7 6 Sel1 repeat DUF1952 PF09189.10 EGB12415.1 - 4.9e-07 29.5 4.8 0.034 14.0 0.0 4.2 4 0 0 4 4 4 3 Domain of unknown function (DUF1952) TRAM PF01938.20 EGB12415.1 - 0.011 15.7 0.0 9.5 6.3 0.0 3.0 3 0 0 3 3 3 0 TRAM domain TPR_6 PF13174.6 EGB12415.1 - 0.013 16.1 6.0 5.4 7.9 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB12415.1 - 0.022 15.5 18.3 24 6.1 0.3 5.5 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB12415.1 - 9.5 6.6 28.6 14 6.1 0.1 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat Thioredoxin PF00085.20 EGB12416.1 - 1.4e-25 89.2 0.0 1.5e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGB12416.1 - 2.8e-08 34.2 0.0 1.7e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGB12416.1 - 1.4e-06 28.6 0.0 0.00018 21.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EGB12416.1 - 3.1e-06 27.1 0.0 3.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGB12416.1 - 1.1e-05 25.2 0.0 0.0014 18.3 0.1 2.0 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 EGB12416.1 - 2.3e-05 24.2 0.0 2.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGB12416.1 - 5.3e-05 22.7 0.0 6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGB12416.1 - 8.4e-05 22.7 0.0 0.00014 22.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EGB12416.1 - 0.0022 17.9 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DIM1 PF02966.16 EGB12416.1 - 0.0069 16.2 0.0 0.0082 15.9 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Phosducin PF02114.16 EGB12416.1 - 0.043 12.8 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_3 PF13192.6 EGB12416.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain UDG PF03167.19 EGB12417.1 - 0.014 15.4 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Ank_2 PF12796.7 EGB12418.1 - 2.3e-10 40.9 0.0 2.4e-06 28.1 0.0 3.9 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB12418.1 - 5.3e-06 26.9 1.5 0.0093 16.5 0.0 4.6 4 2 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12418.1 - 0.00042 20.5 13.7 0.8 10.5 0.0 6.6 7 0 0 7 7 7 1 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 EGB12418.1 - 0.016 16.1 0.0 0.027 15.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ank_5 PF13857.6 EGB12418.1 - 0.03 14.6 8.5 1.4 9.3 0.0 5.4 4 1 3 7 7 7 0 Ankyrin repeats (many copies) Ank PF00023.30 EGB12418.1 - 0.2 12.1 0.0 0.2 12.1 0.0 5.5 6 1 0 6 6 6 0 Ankyrin repeat Lipase_GDSL_3 PF14606.6 EGB12419.1 - 8.1e-29 101.0 0.0 1.4e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family U-box PF04564.15 EGB12419.1 - 5.4e-19 68.1 0.1 1.2e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 U-box domain Lipase_GDSL_2 PF13472.6 EGB12419.1 - 2.2e-11 44.5 0.0 4.4e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CSD PF00313.22 EGB12419.1 - 1.1e-08 34.8 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-Nse PF11789.8 EGB12419.1 - 0.0003 20.6 0.0 0.0007 19.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SR-25 PF10500.9 EGB12419.1 - 0.029 14.0 5.8 0.052 13.1 5.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-RING_UBOX PF13445.6 EGB12419.1 - 0.032 14.3 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-NOSIP PF15906.5 EGB12419.1 - 0.083 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Lipase_GDSL PF00657.22 EGB12419.1 - 0.18 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase RNA_polI_A34 PF08208.11 EGB12419.1 - 2.5 8.2 11.4 4.9 7.2 11.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3381 PF11861.8 EGB12419.1 - 4 7.2 13.0 6.9 6.5 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PseudoU_synth_2 PF00849.22 EGB12420.1 - 1.3e-24 87.1 0.0 2.4e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF393 PF04134.12 EGB12421.1 - 4e-21 76.5 0.3 5.4e-21 76.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 ERG4_ERG24 PF01222.17 EGB12422.1 - 3.2e-61 207.4 10.4 3.9e-61 207.1 10.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGB12422.1 - 7.9e-07 28.8 0.7 1.6e-06 27.9 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Peptidase_M41 PF01434.18 EGB12423.1 - 3.3e-62 209.7 0.5 6.7e-62 208.7 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EGB12423.1 - 5.6e-45 153.0 0.0 1.1e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB12423.1 - 3.2e-10 39.6 0.3 9.4e-10 38.2 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGB12423.1 - 7.4e-07 29.2 0.0 2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGB12423.1 - 0.00011 22.5 0.2 0.15 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EGB12423.1 - 0.00012 21.9 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGB12423.1 - 0.00061 19.1 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EGB12423.1 - 0.0019 18.6 0.4 0.0019 18.6 0.4 4.0 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EGB12423.1 - 0.0056 16.4 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGB12423.1 - 0.0062 17.1 0.0 0.019 15.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain Peptidase_M50B PF13398.6 EGB12423.1 - 0.035 13.7 0.9 0.069 12.8 0.1 1.8 2 0 0 2 2 2 0 Peptidase M50B-like AAA_28 PF13521.6 EGB12423.1 - 0.041 14.1 0.7 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGB12423.1 - 0.045 13.1 0.4 0.096 12.1 0.4 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGB12423.1 - 0.049 13.8 0.1 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EGB12423.1 - 0.049 13.7 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EGB12423.1 - 0.052 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGB12423.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rotamase_2 PF13145.6 EGB12423.1 - 6 7.7 14.3 0.4 11.5 8.2 2.1 2 0 0 2 2 1 0 PPIC-type PPIASE domain ACT_7 PF13840.6 EGB12424.1 - 4.8e-20 71.1 0.0 6.3e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 ACT domain Imm31 PF15591.6 EGB12424.1 - 0.031 14.1 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 31 ACT PF01842.25 EGB12424.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ACT domain RFC1 PF08519.12 EGB12425.1 - 1.2e-38 132.7 0.0 3.8e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 EGB12425.1 - 2.3e-10 41.0 0.0 4.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EGB12425.1 - 3e-06 27.1 0.0 4.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EGB12425.1 - 8.9e-06 26.0 0.0 2.7e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 EGB12425.1 - 0.00027 20.7 0.0 0.00071 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB12425.1 - 0.00099 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB12425.1 - 0.0052 17.2 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PBP1_TM PF14812.6 EGB12425.1 - 0.013 15.9 8.7 0.059 13.8 8.7 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_5 PF07728.14 EGB12425.1 - 0.025 14.6 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EGB12425.1 - 0.03 14.2 0.0 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 NTPase Rad17 PF03215.15 EGB12425.1 - 0.13 12.2 0.0 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain RuvB_N PF05496.12 EGB12425.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Ephrin_rec_like PF07699.13 EGB12426.1 - 1.1e-17 63.5 101.3 2.9e-07 30.1 5.3 10.9 6 3 5 11 11 11 7 Putative ephrin-receptor like VCBS PF13517.6 EGB12426.1 - 4.4e-17 62.4 32.0 2e-10 41.1 8.8 2.9 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB12426.1 - 1.4e-11 44.3 21.1 0.0004 20.4 1.7 3.8 3 0 0 3 3 3 3 FG-GAP repeat BBS2_Mid PF14783.6 EGB12426.1 - 0.009 16.0 0.0 7.1 6.7 0.0 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Laminin_EGF PF00053.24 EGB12426.1 - 0.012 15.7 12.1 0.012 15.7 12.1 9.7 6 4 1 8 8 8 0 Laminin EGF domain TcdB_toxin_midN PF12256.8 EGB12426.1 - 0.99 8.7 8.9 21 4.4 0.5 3.4 2 1 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region NAD_binding_8 PF13450.6 EGB12427.1 - 5.5e-10 39.3 0.0 2e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGB12427.1 - 9.4e-10 38.3 0.0 1.2e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EGB12427.1 - 0.00018 21.2 0.2 0.00098 18.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB12427.1 - 0.0048 16.0 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGB12427.1 - 0.0051 16.1 0.0 0.025 13.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGB12427.1 - 0.0062 16.5 0.0 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EGB12427.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EGB12427.1 - 0.021 13.5 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EGB12427.1 - 0.027 13.5 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EGB12427.1 - 0.11 13.1 0.0 61 4.3 0.0 3.2 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB12427.1 - 0.24 10.5 0.0 0.33 10.0 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A UbiA PF01040.18 EGB12429.1 - 1.3e-47 162.3 26.5 1.6e-47 162.0 26.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Hydrolase_3 PF08282.12 EGB12430.1 - 1.9e-45 155.6 0.0 4.5e-45 154.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB12430.1 - 1.9e-06 28.4 2.1 0.0071 16.6 0.2 3.0 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGB12430.1 - 1.2e-05 24.9 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 EGB12430.1 - 4.7e-05 23.9 1.6 0.1 13.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGB12430.1 - 0.0027 17.8 0.2 0.69 10.0 0.4 2.9 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGB12430.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CDC45 PF02724.14 EGB12431.1 - 0.00059 18.3 4.8 0.00074 18.0 4.8 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 EGB12431.1 - 0.0044 16.5 3.2 0.0057 16.1 3.2 1.1 1 0 0 1 1 1 1 SDA1 DUF4746 PF15928.5 EGB12431.1 - 0.13 11.6 3.7 0.21 11.0 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 EGB12431.1 - 0.2 11.6 5.2 0.28 11.1 5.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 EGB12431.1 - 0.23 10.2 0.3 0.29 9.9 0.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3c_N PF05470.12 EGB12431.1 - 0.35 9.1 2.0 0.42 8.9 2.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 EGB12431.1 - 0.41 8.8 9.8 0.55 8.4 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 EGB12431.1 - 0.42 10.3 5.1 0.84 9.3 5.1 1.5 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 EGB12431.1 - 0.74 9.1 12.5 1.2 8.5 12.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 EGB12431.1 - 0.97 9.2 9.5 0.67 9.7 7.3 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 EGB12431.1 - 1.1 9.0 12.4 1.9 8.1 12.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGB12431.1 - 1.5 6.8 17.2 2.1 6.3 17.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop53 PF07767.11 EGB12431.1 - 2.4 7.5 12.7 4.3 6.6 12.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RXT2_N PF08595.11 EGB12431.1 - 3.2 7.8 7.2 5.7 6.9 7.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAP_alpha PF03896.16 EGB12431.1 - 4.3 6.5 7.7 6.9 5.8 7.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit U-box PF04564.15 EGB12433.1 - 3.7e-16 59.1 0.0 6.5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain SAM_1 PF00536.30 EGB12433.1 - 3.9e-08 33.6 0.0 1.2e-07 32.0 0.0 1.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) zf-RING_UBOX PF13445.6 EGB12433.1 - 5.6e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGB12433.1 - 7.1e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGB12433.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 EGB12433.1 - 0.00013 21.7 0.1 0.00025 20.8 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.17 EGB12433.1 - 0.00026 21.0 0.0 0.00072 19.6 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) zf-RING_2 PF13639.6 EGB12433.1 - 0.0059 16.9 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGB12433.1 - 0.0075 16.5 0.3 0.023 15.0 0.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain HEAT PF02985.22 EGB12434.1 - 1.4 9.4 20.0 0.13 12.6 0.4 5.8 4 0 0 4 4 4 0 HEAT repeat BRO1 PF03097.18 EGB12435.1 - 1e-18 67.4 0.1 3.4e-17 62.4 0.4 2.3 2 1 0 2 2 2 1 BRO1-like domain His_Phos_1 PF00300.22 EGB12435.1 - 1.5e-16 60.7 2.2 6.2e-12 45.6 1.1 2.8 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Lactamase_B_2 PF12706.7 EGB12435.1 - 6.2e-13 48.7 0.5 6.3e-05 22.6 0.0 3.8 3 1 0 3 3 3 2 Beta-lactamase superfamily domain DNA_RNApol_7kD PF03604.13 EGB12435.1 - 1.9e-11 43.4 5.7 5.2e-11 42.0 5.7 1.8 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Lactamase_B PF00753.27 EGB12435.1 - 1.5e-07 31.6 0.0 5.1e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NIPSNAP PF07978.13 EGB12435.1 - 5.8e-05 23.3 6.5 0.0098 16.1 0.0 4.3 3 0 0 3 3 3 2 NIPSNAP A2L_zn_ribbon PF08792.10 EGB12435.1 - 0.021 14.5 1.0 0.052 13.3 1.0 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain MHB PF16525.5 EGB12435.1 - 1.5 9.1 5.7 0.24 11.7 0.5 2.3 2 0 0 2 2 2 0 Haemophore, haem-binding DUF525 PF04379.14 EGB12436.1 - 2.6e-12 46.8 0.0 9.6e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 ApaG domain FGE-sulfatase PF03781.16 EGB12437.1 - 1.2e-50 172.5 4.7 1.4e-50 172.3 4.7 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 ubiquitin PF00240.23 EGB12438.1 - 1.7e-34 117.4 0.5 2.6e-34 116.8 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EGB12438.1 - 1.4e-19 70.0 1.1 2.7e-19 69.1 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EGB12438.1 - 7.6e-16 57.7 0.7 1.3e-15 56.9 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB12438.1 - 1.8e-06 28.3 0.4 3.1e-05 24.3 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB12438.1 - 0.00011 22.2 0.3 0.00029 20.9 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGB12438.1 - 0.0015 19.0 0.7 0.0022 18.5 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 EGB12438.1 - 0.0023 17.8 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGB12438.1 - 0.0075 16.6 0.4 0.013 15.9 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGB12438.1 - 0.14 12.2 0.7 8.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Aminotran_1_2 PF00155.21 EGB12439.1 - 1.9e-30 106.2 0.0 2.4e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGB12439.1 - 0.13 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Exostosin PF03016.15 EGB12440.1 - 2.8e-21 76.0 0.0 5.9e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 Exostosin family Thioredoxin PF00085.20 EGB12440.1 - 7e-18 64.5 0.0 2.3e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin SET PF00856.28 EGB12440.1 - 1.9e-05 25.1 0.0 0.00028 21.3 0.0 2.5 1 1 0 1 1 1 1 SET domain AhpC-TSA PF00578.21 EGB12440.1 - 0.00086 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family WD40 PF00400.32 EGB12440.1 - 0.0014 19.4 6.5 3.1 8.8 0.0 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12440.1 - 0.0061 16.8 0.0 3.7 7.9 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Thioredoxin_9 PF14595.6 EGB12440.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 EGB12440.1 - 0.043 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB12440.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.10 EGB12440.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Redoxin Sigma70_ner PF04546.13 EGB12440.1 - 0.17 11.8 0.3 0.37 10.6 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region GCIP PF13324.6 EGB12440.1 - 0.19 11.3 0.2 0.34 10.5 0.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 EGB12440.1 - 0.99 7.4 4.9 1.5 6.8 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi THUMP PF02926.17 EGB12441.1 - 5.7e-08 33.0 0.0 5.4e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 THUMP domain DUF3597 PF12200.8 EGB12441.1 - 0.038 14.5 0.5 0.038 14.5 0.5 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3597) DNAPolymera_Pol PF11590.8 EGB12441.1 - 0.083 12.8 5.7 0.68 9.9 0.9 2.4 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol CW_binding_2 PF04122.12 EGB12441.1 - 0.83 10.4 5.5 2.2 9.0 5.5 1.9 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 CCDC53 PF10152.9 EGB12442.1 - 0.00036 21.0 0.2 0.00051 20.5 0.2 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex EzrA PF06160.12 EGB12442.1 - 0.017 13.3 0.2 0.019 13.2 0.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CRS1_YhbY PF01985.21 EGB12442.1 - 0.11 12.6 0.4 0.15 12.3 0.3 1.4 1 1 0 1 1 1 0 CRS1 / YhbY (CRM) domain CSD PF00313.22 EGB12443.1 - 6.5e-25 86.8 0.0 1.7e-11 43.8 0.0 4.2 3 2 0 3 3 3 3 'Cold-shock' DNA-binding domain Pox_Ag35 PF03286.14 EGB12443.1 - 0.016 15.0 10.7 0.031 14.1 10.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 EGB12443.1 - 0.23 11.5 0.6 0.41 10.7 0.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_Rpo13 PF12136.8 EGB12443.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain CDC27 PF09507.10 EGB12443.1 - 3 7.1 12.1 4.4 6.6 12.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Astro_capsid_p PF12226.8 EGB12443.1 - 6.8 5.7 5.2 12 5.0 5.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DSBA PF01323.20 EGB12444.1 - 4.4e-16 59.2 0.0 6.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EGB12444.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Tyrosinase PF00264.20 EGB12445.1 - 2.8e-08 34.3 7.9 1.1e-06 29.1 2.5 2.9 2 2 0 2 2 2 2 Common central domain of tyrosinase C2 PF00168.30 EGB12446.1 - 2.1e-34 117.9 0.0 6.5e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 EGB12448.1 - 0.019 15.4 0.2 0.054 13.9 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EGB12448.1 - 0.027 14.0 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 EF hand Ion_trans_2 PF07885.16 EGB12449.1 - 5.4e-16 58.3 4.3 8.1e-16 57.8 4.3 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB12449.1 - 0.038 13.2 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein TUDOR_5 PF18359.1 EGB12450.1 - 0.00012 21.7 0.9 0.00025 20.7 0.9 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 TonB_N PF16031.5 EGB12450.1 - 0.02 15.4 35.4 0.02 15.4 35.4 7.3 6 1 1 7 7 7 0 TonB polyproline region Herpes_capsid PF06112.11 EGB12450.1 - 6.7 6.8 8.6 15 5.6 8.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cyt-b5 PF00173.28 EGB12451.1 - 0.00038 20.5 0.0 0.0013 18.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Ammonium_transp PF00909.21 EGB12452.1 - 1.1e-105 353.6 29.4 1.4e-105 353.3 29.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family JmjC PF02373.22 EGB12453.1 - 1.4e-38 131.8 0.6 6.3e-38 129.7 0.5 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 EGB12453.1 - 1.1e-13 51.3 12.6 2.4e-13 50.2 12.6 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger Proteasome PF00227.26 EGB12455.1 - 1.5e-32 112.7 0.1 1.7e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Ank_2 PF12796.7 EGB12456.1 - 1.6e-11 44.6 0.0 4.5e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB12456.1 - 1e-10 41.6 0.2 1.9e-08 34.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB12456.1 - 1.6e-10 41.3 0.0 4.8e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB12456.1 - 3.3e-10 39.9 0.2 7e-07 29.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGB12456.1 - 8.9e-10 38.0 0.0 0.00013 22.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat SR-25 PF10500.9 EGB12456.1 - 0.0014 18.3 2.8 0.0014 18.3 2.8 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Peptidase_C37 PF05416.12 EGB12456.1 - 0.14 10.6 1.5 0.23 9.9 1.5 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase RNA_polI_A34 PF08208.11 EGB12456.1 - 0.6 10.2 14.2 0.033 14.3 8.2 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S49_N PF08496.10 EGB12456.1 - 1.6 8.8 5.4 3.1 7.8 5.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.9 EGB12456.1 - 1.9 8.4 8.5 3.3 7.6 8.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MgtC PF02308.16 EGB12457.1 - 2.9e-26 92.2 17.2 5.8e-26 91.2 17.2 1.5 1 0 0 1 1 1 1 MgtC family zf-PARP PF00645.18 EGB12457.1 - 3.9e-12 46.9 0.4 8.1e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DAGAT PF03982.13 EGB12458.1 - 5.4e-27 94.5 0.0 6e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PI3_PI4_kinase PF00454.27 EGB12459.1 - 4.5e-29 102.0 0.0 6.2e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Peptidase_C97 PF05903.14 EGB12460.1 - 1.5e-27 96.3 0.0 1.7e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Pkinase PF00069.25 EGB12461.1 - 3.2e-39 134.9 0.0 2.1e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12461.1 - 5.2e-17 62.0 0.0 8.6e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3856 PF12968.7 EGB12461.1 - 0.0019 18.3 0.1 0.0038 17.3 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) Peptidase_S49_N PF08496.10 EGB12461.1 - 0.04 14.0 2.2 0.078 13.0 2.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CCDC-167 PF15188.6 EGB12461.1 - 0.066 13.6 3.6 0.14 12.5 3.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PPP4R2 PF09184.11 EGB12461.1 - 1.2 8.7 12.6 0.18 11.4 7.9 1.9 2 0 0 2 2 2 0 PPP4R2 SQHop_cyclase_C PF13243.6 EGB12462.1 - 1.9e-47 161.9 6.6 5.8e-42 143.9 1.5 2.5 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGB12462.1 - 4.3e-47 160.6 0.1 1.8e-41 142.2 0.0 4.5 4 1 1 5 5 5 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EGB12462.1 - 3.9e-24 84.1 19.4 5.5e-06 26.0 0.0 7.0 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EGB12462.1 - 0.011 15.0 0.0 16 4.7 0.0 3.6 4 0 0 4 4 4 0 Pectic acid lyase Sel1 PF08238.12 EGB12463.1 - 1.3e-52 175.1 47.2 3.9e-09 36.9 0.1 10.9 11 1 0 11 11 11 9 Sel1 repeat B12-binding_2 PF02607.17 EGB12463.1 - 0.002 18.5 0.3 31 5.1 0.0 4.0 3 1 1 4 4 4 0 B12 binding domain TPR_16 PF13432.6 EGB12463.1 - 0.0049 17.5 5.8 0.0049 17.5 5.8 6.3 8 1 0 8 8 8 2 Tetratricopeptide repeat Prok-RING_4 PF14447.6 EGB12463.1 - 0.028 14.3 1.7 0.049 13.5 1.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF977 PF06163.11 EGB12463.1 - 0.041 13.8 4.5 2.5 8.1 0.0 3.8 2 2 2 5 5 5 0 Bacterial protein of unknown function (DUF977) zf-C3HC4_3 PF13920.6 EGB12463.1 - 0.16 11.9 1.5 0.3 11.0 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_3 PF07720.12 EGB12463.1 - 0.62 10.1 4.3 48 4.1 0.0 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4447 PF14590.6 EGB12464.1 - 0.2 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) LRR_6 PF13516.6 EGB12466.1 - 2.4e-05 24.0 0.2 2.8 8.2 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeat zn-ribbon_14 PF16503.5 EGB12466.1 - 0.53 9.8 3.7 9.4 5.8 0.1 3.4 3 0 0 3 3 3 0 Zinc-ribbon Ribosomal_L30_N PF08079.12 EGB12467.1 - 3e-23 81.8 14.1 4.9e-23 81.2 14.1 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGB12467.1 - 1.4e-21 76.1 1.1 2.5e-21 75.3 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Melibiase_2 PF16499.5 EGB12468.1 - 8.4e-38 130.1 0.0 1.1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGB12468.1 - 8.9e-21 73.7 0.1 3.1e-20 72.0 0.1 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGB12468.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Melibiase Melibiase_2_C PF17450.2 EGB12468.1 - 0.016 15.4 0.0 0.061 13.6 0.0 1.9 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain AAA_6 PF12774.7 EGB12469.1 - 2.6e-11 43.1 0.0 2.7e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 EGB12469.1 - 0.029 14.9 0.0 0.036 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGB12469.1 - 0.25 10.8 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region RRF PF01765.19 EGB12470.1 - 6.5e-61 205.0 1.2 7.3e-61 204.9 1.2 1.0 1 0 0 1 1 1 1 Ribosome recycling factor YtxH PF12732.7 EGB12470.1 - 0.16 12.6 6.0 0.32 11.6 5.9 1.6 1 1 0 1 1 1 0 YtxH-like protein Kinesin PF00225.23 EGB12471.1 - 1.4e-29 103.1 0.0 1.5e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB12471.1 - 1.8e-16 60.4 0.0 2e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding adh_short PF00106.25 EGB12472.1 - 1.7e-16 60.3 0.1 3.7e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB12472.1 - 4.2e-16 59.2 0.4 8.5e-16 58.2 0.4 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase fn3 PF00041.21 EGB12472.1 - 0.00083 19.7 0.0 0.51 10.7 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain WW PF00397.26 EGB12472.1 - 0.026 14.6 2.1 0.07 13.2 2.1 1.8 1 0 0 1 1 1 0 WW domain SAM_1 PF00536.30 EGB12472.1 - 0.061 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Methyltransf_4 PF02390.17 EGB12473.1 - 7.1e-43 146.1 0.0 9.1e-43 145.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EGB12473.1 - 0.00046 19.8 0.0 0.0031 17.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGB12473.1 - 0.0017 19.0 0.0 0.0036 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB12473.1 - 0.015 15.9 0.1 0.5 11.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGB12473.1 - 0.028 15.2 0.0 0.095 13.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Aminotran_3 PF00202.21 EGB12474.1 - 2.1e-83 280.3 0.0 2.5e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NAGLU PF05089.12 EGB12475.1 - 8.5e-50 169.6 0.4 1e-49 169.3 0.4 1.0 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Lyase_1 PF00206.20 EGB12476.1 - 7.3e-102 340.9 0.0 9e-102 340.6 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGB12476.1 - 1.2e-22 80.1 0.1 4.5e-22 78.2 0.0 2.1 2 0 0 2 2 2 1 Fumarase C C-terminus SBP_bac_3 PF00497.20 EGB12476.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Alpha_kinase PF02816.18 EGB12477.1 - 4.4e-41 141.0 0.0 6.1e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Sulfatase PF00884.23 EGB12478.1 - 1.4e-26 93.7 0.0 1.6e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 EGB12478.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Ribosomal_L33 PF00471.20 EGB12479.1 - 2e-12 47.3 0.1 2.4e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 HP0268 PF18618.1 EGB12479.1 - 0.13 12.7 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 HP0268 Cyclin_N PF00134.23 EGB12480.1 - 5.6e-49 165.1 5.8 4.3e-45 152.6 0.8 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGB12480.1 - 1.1e-28 99.7 5.7 1.3e-28 99.5 2.8 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Glyco_hydro_18 PF00704.28 EGB12481.1 - 7.7e-28 98.1 0.0 9.5e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 XAP5 PF04921.14 EGB12482.1 - 7e-61 206.2 0.0 1.5e-60 205.1 0.0 1.7 1 1 0 1 1 1 1 XAP5, circadian clock regulator CCDC53 PF10152.9 EGB12483.1 - 1.9e-24 86.8 0.1 8.7e-12 45.7 0.0 2.9 2 0 0 2 2 2 2 Subunit CCDC53 of WASH complex WW PF00397.26 EGB12483.1 - 3.5e-07 30.2 2.8 5.8e-07 29.5 2.8 1.4 1 0 0 1 1 1 1 WW domain FH2 PF02181.23 EGB12483.1 - 1.4e-06 27.7 0.0 2.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain 53-BP1_Tudor PF09038.10 EGB12483.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Dynamin_N PF00350.23 EGB12484.1 - 4.1e-24 85.5 0.0 4.8e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB12484.1 - 9.6e-07 28.9 0.0 2.5e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGB12484.1 - 0.0006 19.2 0.1 0.99 8.7 0.1 2.1 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 EGB12484.1 - 0.021 15.1 0.0 3 8.1 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase 2Fe-2S_thioredx PF01257.19 EGB12485.1 - 2.3e-57 192.9 0.1 3e-57 192.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Gar1 PF04410.14 EGB12487.1 - 3.9e-25 88.4 0.0 9.3e-25 87.2 0.0 1.5 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region DUF616 PF04765.13 EGB12487.1 - 1.2e-14 54.4 0.0 1.9e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF616) HSF_DNA-bind PF00447.17 EGB12487.1 - 3.1e-09 37.3 0.0 1.1e-08 35.6 0.0 1.8 1 1 0 1 1 1 1 HSF-type DNA-binding Glyco_hydro_43 PF04616.14 EGB12487.1 - 2e-08 33.9 0.2 6.1e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 O-FucT PF10250.9 EGB12487.1 - 0.0004 20.2 0.4 0.21 11.3 0.0 3.3 4 0 0 4 4 4 1 GDP-fucose protein O-fucosyltransferase ABC_tran PF00005.27 EGB12488.1 - 6.1e-42 143.4 0.0 1.2e-19 71.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB12488.1 - 3.5e-19 69.7 0.0 0.00053 19.9 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EGB12488.1 - 1.1e-14 54.2 2.8 1.1e-14 54.2 2.8 3.6 4 0 0 4 4 3 1 ABC transporter AAA_29 PF13555.6 EGB12488.1 - 3e-08 33.3 0.0 0.0083 15.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGB12488.1 - 1.8e-07 30.8 7.0 0.68 9.3 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGB12488.1 - 5.9e-06 26.2 0.0 0.11 12.2 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 EGB12488.1 - 1.5e-05 25.4 0.1 0.21 12.0 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGB12488.1 - 3.7e-05 23.7 0.0 0.01 15.8 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EGB12488.1 - 8.1e-05 22.8 0.6 0.34 11.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EGB12488.1 - 0.00011 22.2 0.0 0.84 9.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGB12488.1 - 0.0004 20.7 1.1 0.49 10.7 0.1 3.2 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGB12488.1 - 0.00068 20.2 0.1 0.04 14.4 0.0 4.7 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.6 EGB12488.1 - 0.0011 19.5 0.0 1.5 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGB12488.1 - 0.0018 18.7 6.3 0.61 10.5 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain TsaE PF02367.17 EGB12488.1 - 0.0034 17.4 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGB12488.1 - 0.0081 16.5 0.0 2.9 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 EGB12488.1 - 0.0096 15.8 1.8 4.3 7.2 0.0 3.2 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.22 EGB12488.1 - 0.011 14.9 0.0 4 6.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EGB12488.1 - 0.013 15.2 0.1 1.7 8.3 0.0 2.9 4 0 0 4 4 2 0 AAA domain PduV-EutP PF10662.9 EGB12488.1 - 0.035 13.8 0.0 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EGB12488.1 - 0.038 14.2 6.1 2.4 8.4 0.1 3.2 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 EGB12488.1 - 0.039 13.7 0.1 19 5.0 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 EGB12488.1 - 0.05 13.8 0.4 4.2 7.7 0.3 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MukB PF04310.12 EGB12488.1 - 0.069 13.0 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_5 PF07728.14 EGB12488.1 - 0.071 13.1 0.1 10 6.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGB12488.1 - 0.082 12.6 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 EGB12488.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DUF87 PF01935.17 EGB12488.1 - 0.13 12.4 0.9 4.3 7.4 0.0 2.9 2 1 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 EGB12488.1 - 0.14 11.3 0.3 5.6 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MeaB PF03308.16 EGB12488.1 - 0.14 11.1 1.2 17 4.3 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGB12488.1 - 0.16 11.9 0.7 4.5 7.2 0.0 3.0 3 0 0 3 3 3 0 NTPase SlyX PF04102.12 EGB12488.1 - 0.64 10.7 2.7 2.3 8.9 1.0 2.7 2 0 0 2 2 2 0 SlyX Hemerythrin PF01814.23 EGB12488.1 - 5 7.8 10.5 0.7 10.5 5.4 2.2 2 0 0 2 2 1 0 Hemerythrin HHE cation binding domain SRP54 PF00448.22 EGB12488.1 - 9 5.9 10.0 10 5.7 0.2 3.7 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain Pkinase PF00069.25 EGB12489.1 - 3.5e-51 174.1 0.0 4.2e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12489.1 - 8.2e-24 84.3 0.0 1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB12489.1 - 0.00036 19.9 0.2 0.0019 17.6 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mpv17_PMP22 PF04117.12 EGB12490.1 - 2.6e-09 37.2 0.1 6.6e-09 35.9 0.1 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family ANAPC10 PF03256.16 EGB12491.1 - 6e-64 215.1 0.0 8.9e-64 214.5 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EGB12491.1 - 0.0075 16.4 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Ion_trans PF00520.31 EGB12492.1 - 1.4e-22 80.1 2.7 2.1e-22 79.6 2.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB12492.1 - 5.5e-16 58.3 3.0 1.5e-15 56.9 3.0 1.8 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGB12492.1 - 3.8e-11 42.9 0.1 6.7e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 EGB12492.1 - 0.19 11.5 0.2 0.38 10.5 0.2 1.5 1 0 0 1 1 1 0 Cupin domain UPF0051 PF01458.17 EGB12493.1 - 5.9e-54 183.0 0.0 7.2e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Cupin_8 PF13621.6 EGB12494.1 - 0.0037 17.0 0.0 0.022 14.5 0.2 2.0 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 EGB12494.1 - 0.058 13.8 0.0 0.32 11.4 0.0 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase AhpC-TSA PF00578.21 EGB12495.1 - 3.7e-08 33.3 0.0 5.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGB12495.1 - 0.062 13.0 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin Sulfotransfer_2 PF03567.14 EGB12496.1 - 3.7e-05 23.8 0.0 0.00026 21.0 0.0 2.2 2 1 0 2 2 2 1 Sulfotransferase family TadF PF16964.5 EGB12496.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F Glyco_transf_10 PF00852.19 EGB12497.1 - 3.3e-07 30.2 0.0 6.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Sulfotransfer_3 PF13469.6 EGB12497.1 - 1.8e-06 28.5 0.4 0.17 12.3 0.0 3.8 4 0 0 4 4 4 2 Sulfotransferase family MS_channel PF00924.18 EGB12498.1 - 1.1e-26 93.7 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel DnaJ_C PF01556.18 EGB12499.1 - 6.9e-24 84.6 0.0 9.7e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB12499.1 - 1.7e-21 76.1 1.1 2.6e-21 75.5 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGB12499.1 - 1.2e-08 35.2 6.6 2.2e-08 34.3 6.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGB12499.1 - 0.0014 18.5 12.5 0.0086 16.0 3.1 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein PP2C PF00481.21 EGB12500.1 - 5.7e-47 160.5 0.0 6.6e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGB12500.1 - 0.024 14.3 1.0 0.044 13.4 0.8 1.9 1 1 0 1 1 1 0 Protein phosphatase 2C DUF1485 PF07364.12 EGB12500.1 - 0.037 13.3 0.7 0.74 9.0 0.1 2.1 2 0 0 2 2 2 0 Metallopeptidase family M81 SRP54 PF00448.22 EGB12501.1 - 4.3e-72 241.9 0.2 4.3e-72 241.9 0.2 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGB12501.1 - 7.4e-25 87.5 2.2 7.4e-25 87.5 2.2 2.1 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 EGB12501.1 - 2.5e-13 50.1 0.2 7.1e-13 48.6 0.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 EGB12501.1 - 2.1e-05 23.9 0.1 5.8e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EGB12501.1 - 6.1e-05 23.2 0.5 0.00016 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB12501.1 - 0.00018 22.0 0.4 0.00018 22.0 0.4 2.1 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 EGB12501.1 - 0.00065 20.0 0.2 0.0028 17.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EGB12501.1 - 0.0092 15.9 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 1 Adenylylsulphate kinase ParA PF10609.9 EGB12501.1 - 0.012 15.1 0.3 0.073 12.5 0.1 2.1 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase 2-oxoacid_dh PF00198.23 EGB12501.1 - 0.015 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) cobW PF02492.19 EGB12501.1 - 0.017 14.7 0.3 0.045 13.3 0.3 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 EGB12501.1 - 0.019 15.0 0.0 0.08 13.0 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GET2 PF08690.10 EGB12501.1 - 0.026 14.2 1.3 0.049 13.3 1.3 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 AAA_24 PF13479.6 EGB12501.1 - 0.039 13.7 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGB12501.1 - 0.04 14.0 0.2 0.67 10.1 0.1 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 EGB12501.1 - 0.044 13.5 3.2 0.36 10.5 0.1 2.7 3 0 0 3 3 2 0 Thymidylate kinase AAA_18 PF13238.6 EGB12501.1 - 0.047 14.2 1.0 0.15 12.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 EGB12501.1 - 0.05 13.5 0.7 0.2 11.5 0.2 2.3 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 EGB12501.1 - 0.05 13.8 1.4 0.12 12.6 0.2 2.2 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 EGB12501.1 - 0.072 12.3 0.2 0.38 9.9 0.1 2.2 1 1 1 2 2 2 0 Anion-transporting ATPase ATPase PF06745.13 EGB12501.1 - 0.099 12.0 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 EGB12501.1 - 0.11 13.0 0.0 0.79 10.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KTI12 PF08433.10 EGB12501.1 - 0.15 11.5 0.0 0.43 10.0 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 EGB12501.1 - 0.55 9.8 11.0 0.5 9.9 3.3 3.5 2 2 1 3 3 3 0 AAA domain AAA_17 PF13207.6 EGB12501.1 - 1.1 9.7 8.0 0.43 11.0 0.2 3.5 4 2 0 4 4 4 0 AAA domain DNA_pol_B PF00136.21 EGB12502.1 - 3.3e-53 181.0 0.0 4.6e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGB12502.1 - 3e-06 26.6 0.0 1.2e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF5429 PF17494.2 EGB12502.1 - 0.1 12.6 3.3 0.07 13.2 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5429) PQ-loop PF04193.14 EGB12503.1 - 5.1e-37 125.4 3.2 9.1e-18 63.8 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat UAA PF08449.11 EGB12504.1 - 1.2e-33 116.6 1.7 1.3e-33 116.5 1.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGB12504.1 - 0.0011 19.1 3.2 0.0011 19.1 3.2 2.9 3 1 0 3 3 3 2 EamA-like transporter family YrhK PF14145.6 EGB12504.1 - 0.038 13.9 0.1 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 YrhK-like protein Peptidase_C97 PF05903.14 EGB12505.1 - 1.4e-29 102.9 0.1 1.7e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain XG_FTase PF03254.13 EGB12506.1 - 0.04 12.5 0.1 0.058 12.0 0.1 1.1 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Myelin-PO_C PF10570.9 EGB12506.1 - 0.17 12.4 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Myelin-PO cytoplasmic C-term p65 binding region PI-PLC-X PF00388.19 EGB12507.1 - 5.8e-42 142.7 0.0 1.1e-41 141.8 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGB12507.1 - 1.2e-26 93.3 0.0 2.3e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGB12507.1 - 7.1e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ntox15 PF15604.6 EGB12507.1 - 0.25 11.5 0.2 0.39 10.8 0.2 1.2 1 0 0 1 1 1 0 Novel toxin 15 HAD_2 PF13419.6 EGB12508.1 - 3.5e-09 37.0 0.0 4.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB12508.1 - 1.4e-07 32.0 0.2 1.9e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB12508.1 - 7.6e-07 29.1 0.2 1.8e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Flu_NP PF00506.18 EGB12508.1 - 0.22 10.1 0.1 0.28 9.8 0.1 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein Cwf_Cwc_15 PF04889.12 EGB12509.1 - 0.068 12.9 5.6 0.12 12.1 5.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3275 PF11679.8 EGB12509.1 - 1.8 8.5 7.3 0.66 9.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) DNA_pol_phi PF04931.13 EGB12509.1 - 4 5.4 6.6 6.5 4.7 6.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi PHD PF00628.29 EGB12510.1 - 1.2e-07 31.5 15.0 2.2e-07 30.6 15.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGB12510.1 - 3.7e-07 29.6 8.5 9.6e-07 28.3 8.5 1.8 1 0 0 1 1 1 1 PHD-finger LBR_tudor PF09465.10 EGB12510.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain CENP-B_dimeris PF09026.10 EGB12510.1 - 0.18 12.2 3.9 0.52 10.7 3.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Radial_spoke PF04712.12 EGB12510.1 - 0.32 9.9 1.4 0.48 9.3 1.4 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein PAC1 PF16094.5 EGB12510.1 - 0.51 9.5 2.1 0.96 8.6 2.1 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Prok-RING_1 PF14446.6 EGB12510.1 - 1.1 9.3 11.4 2.2 8.3 11.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CA_like PF10563.9 EGB12511.1 - 2e-45 154.9 5.1 4.2e-36 124.5 1.2 2.2 1 1 1 2 2 2 2 Putative carbonic anhydrase CLP_protease PF00574.23 EGB12512.1 - 3.8e-75 251.8 0.1 6.6e-75 251.0 0.1 1.3 1 0 0 1 1 1 1 Clp protease ABC_tran PF00005.27 EGB12512.1 - 1.1e-43 149.0 0.0 4.3e-23 82.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGB12512.1 - 7.1e-17 62.2 0.0 0.0017 18.2 0.3 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EGB12512.1 - 7.2e-15 54.8 4.1 7.2e-15 54.8 4.1 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGB12512.1 - 3.7e-13 49.4 0.5 0.003 17.0 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGB12512.1 - 4.3e-08 32.8 0.1 0.0065 16.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGB12512.1 - 4.7e-08 33.8 6.0 0.011 16.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGB12512.1 - 5.9e-05 23.0 0.0 0.18 11.7 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGB12512.1 - 0.00016 22.1 6.2 0.015 15.7 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain ABC_tran_CTD PF16326.5 EGB12512.1 - 0.00029 21.0 9.3 0.00049 20.3 4.2 3.0 2 0 0 2 2 2 1 ABC transporter C-terminal domain AAA_27 PF13514.6 EGB12512.1 - 0.00048 19.8 2.4 0.68 9.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EGB12512.1 - 0.00056 20.1 4.7 0.22 11.7 0.0 3.2 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.23 EGB12512.1 - 0.00079 19.5 1.0 0.68 10.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 EGB12512.1 - 0.0018 18.2 0.5 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EGB12512.1 - 0.0034 17.7 0.5 3.7 7.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGB12512.1 - 0.006 17.1 0.5 5.4 7.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 EGB12512.1 - 0.0067 15.5 0.1 3.6 6.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.19 EGB12512.1 - 0.0097 15.5 0.1 1.7 8.2 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EGB12512.1 - 0.0098 16.1 8.9 0.47 10.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain MeaB PF03308.16 EGB12512.1 - 0.011 14.8 2.2 1.4 7.8 0.0 3.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGB12512.1 - 0.012 15.7 1.8 2.7 8.0 0.1 2.8 3 0 0 3 3 2 0 Dynamin family RNA_helicase PF00910.22 EGB12512.1 - 0.014 15.8 0.6 8.3 6.9 0.0 3.4 3 0 0 3 3 3 0 RNA helicase SbcCD_C PF13558.6 EGB12512.1 - 0.051 13.8 0.2 19 5.6 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EGB12512.1 - 0.055 13.9 0.3 3.2 8.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGB12512.1 - 0.078 12.7 0.2 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGB12512.1 - 0.078 12.9 1.7 6 6.7 0.1 2.6 3 0 0 3 3 2 0 NTPase DUF815 PF05673.13 EGB12512.1 - 0.12 11.5 0.2 0.77 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 EGB12512.1 - 0.15 11.7 0.2 4.7 6.8 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 EGB12512.1 - 0.25 11.1 1.9 14 5.3 0.3 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 EGB12512.1 - 0.71 8.6 3.0 20 3.8 0.4 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 EGB12512.1 - 1.5 8.1 6.3 5.1 6.3 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.6 EGB12512.1 - 9.8 5.8 25.1 0.12 12.1 1.6 4.8 5 2 0 5 5 5 0 AAA domain CTNNBL PF08216.11 EGB12513.1 - 9.1e-11 41.9 0.0 2.7e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm_3 PF16186.5 EGB12513.1 - 0.0026 17.3 0.0 0.036 13.6 0.0 2.2 2 0 0 2 2 2 1 Atypical Arm repeat SEN1_N PF12726.7 EGB12513.1 - 0.11 10.7 0.1 0.13 10.4 0.1 1.5 1 1 0 1 1 1 0 SEN1 N terminal MBF1 PF08523.10 EGB12514.1 - 7.5e-15 55.1 2.8 7.5e-15 55.1 2.8 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EGB12514.1 - 3.2e-12 46.3 0.1 5e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EGB12514.1 - 9.6e-06 25.9 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EGB12514.1 - 0.0002 21.3 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain PRR18 PF15671.5 EGB12514.1 - 0.032 14.1 1.4 0.041 13.8 1.4 1.1 1 0 0 1 1 1 0 Proline-rich protein family 18 ECF-ribofla_trS PF07155.12 EGB12514.1 - 0.19 11.7 0.1 0.25 11.3 0.1 1.1 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component TPR_2 PF07719.17 EGB12515.1 - 0.0078 16.3 0.5 0.0078 16.3 0.5 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB12515.1 - 0.019 15.1 1.9 2.7 8.5 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12515.1 - 0.1 12.5 9.3 0.18 11.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB12515.1 - 8.1 6.7 9.8 1.1e+02 3.2 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 EGB12516.1 - 4.4e-19 68.9 0.1 9.8e-19 67.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB12516.1 - 1.4e-15 57.5 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB12516.1 - 2.6e-13 50.5 0.0 6.6e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB12516.1 - 6.2e-08 33.3 0.0 1.1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGB12516.1 - 8.6e-07 28.5 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGB12516.1 - 2.1e-06 27.6 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGB12516.1 - 3.8e-05 23.6 0.1 9.8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EGB12516.1 - 0.041 12.5 0.0 0.06 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DEAD PF00270.29 EGB12517.1 - 5.1e-08 32.9 0.0 0.01 15.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Spc7 PF08317.11 EGB12517.1 - 0.25 10.2 4.5 0.4 9.5 4.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Herpes_UL25 PF01499.16 EGB12517.1 - 0.39 9.2 3.9 0.57 8.6 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family ASFV_J13L PF05568.11 EGB12517.1 - 3.5 7.3 10.3 0.099 12.4 3.7 1.8 2 0 0 2 2 2 0 African swine fever virus J13L protein ABC_tran PF00005.27 EGB12518.1 - 7e-24 84.9 0.0 1.2e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGB12518.1 - 1e-14 54.5 19.5 1.7e-14 53.8 19.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_25 PF13481.6 EGB12518.1 - 0.0012 18.5 0.2 0.0055 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SWIM PF04434.17 EGB12518.1 - 0.0015 18.2 1.2 0.0036 16.9 1.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger AAA_16 PF13191.6 EGB12518.1 - 0.0018 18.7 0.1 0.0051 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGB12518.1 - 0.0018 18.2 0.1 0.02 14.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EGB12518.1 - 0.0027 18.2 0.0 0.0045 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 EGB12518.1 - 0.0057 15.8 12.5 0.009 15.2 12.5 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA PF00004.29 EGB12518.1 - 0.052 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGB12518.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGB12518.1 - 0.075 12.8 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EGB12518.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 EGB12518.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EGB12518.1 - 0.13 12.2 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 EGB12518.1 - 0.21 11.0 0.0 0.69 9.3 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain YrhC PF14143.6 EGB12518.1 - 1.7 8.8 7.9 0.33 11.1 2.7 2.3 2 0 0 2 2 2 0 YrhC-like protein ABC2_membrane_2 PF12679.7 EGB12518.1 - 3.3 6.9 14.0 10 5.3 14.0 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein APG12 PF04110.13 EGB12519.1 - 5.9e-21 74.7 0.0 6.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ax_dynein_light PF10211.9 EGB12520.1 - 6.7e-88 293.5 12.1 7.9e-88 293.3 12.1 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain ERM PF00769.19 EGB12520.1 - 0.013 15.3 13.7 0.013 15.3 13.7 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Nup88 PF10168.9 EGB12520.1 - 0.19 9.5 9.8 0.23 9.2 9.8 1.1 1 0 0 1 1 1 0 Nuclear pore component UPF0242 PF06785.11 EGB12520.1 - 1.5 8.9 10.7 0.49 10.5 7.8 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAUS6_N PF14661.6 EGB12520.1 - 1.5 8.3 11.4 2.4 7.7 11.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Striatin PF08232.12 EGB12520.1 - 3.6 8.2 17.1 0.32 11.6 11.8 1.9 2 1 0 2 2 2 0 Striatin family WD40_alt PF14077.6 EGB12520.1 - 4.4 7.2 7.9 7.8 6.4 1.1 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif Spc24 PF08286.11 EGB12520.1 - 9.8 6.5 9.2 9.1 6.6 7.4 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 C1_1 PF00130.22 EGB12521.1 - 0.001 18.9 0.8 0.0047 16.8 0.0 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 EGB12521.1 - 0.0025 17.6 0.5 0.0025 17.6 0.5 3.2 3 0 0 3 3 3 1 PHD-finger DnaJ PF00226.31 EGB12521.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain C1_2 PF03107.16 EGB12521.1 - 8.6 6.8 7.0 32 4.9 0.0 3.8 4 1 0 4 4 4 0 C1 domain Bromodomain PF00439.25 EGB12523.1 - 2.5e-15 56.3 0.0 4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain zf-CCHC_5 PF14787.6 EGB12524.1 - 0.12 12.1 0.4 0.26 11.0 0.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Glyco_transf_92 PF01697.27 EGB12525.1 - 0.00082 19.1 0.0 0.013 15.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EGB12525.1 - 0.0026 18.2 0.1 0.0067 16.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 DUF5076 PF16826.5 EGB12526.1 - 0.24 11.4 0.7 0.47 10.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5076) KR PF08659.10 EGB12527.1 - 7.3e-39 133.5 0.1 1.7e-38 132.4 0.1 1.6 1 0 0 1 1 1 1 KR domain Myb_DNA-binding PF00249.31 EGB12527.1 - 4.1e-08 33.3 0.6 9.7e-08 32.1 0.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB12527.1 - 1.3e-07 31.8 0.1 7.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain adh_short_C2 PF13561.6 EGB12527.1 - 7.9e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB12527.1 - 0.001 18.6 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Myb_DNA-bind_5 PF13873.6 EGB12527.1 - 0.0077 16.3 2.3 0.1 12.7 0.8 2.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGB12527.1 - 0.0086 16.3 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EGB12527.1 - 0.14 12.5 1.8 0.38 11.1 0.7 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PBP1_TM PF14812.6 EGB12527.1 - 9.7 6.6 22.4 4.7 7.6 2.9 4.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_23 PF13489.6 EGB12529.1 - 3.8e-13 49.6 0.0 4.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB12529.1 - 5.7e-10 39.8 0.3 1.6e-09 38.3 0.3 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB12529.1 - 1.7e-08 35.1 0.0 2.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB12529.1 - 6e-08 33.2 0.6 4.1e-07 30.6 0.6 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB12529.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EGB12529.1 - 0.012 15.1 0.0 0.04 13.4 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain MORN PF02493.20 EGB12530.1 - 2.1e-61 200.3 99.8 5.6e-07 29.1 0.1 15.3 15 1 0 15 15 15 14 MORN repeat DUF448 PF04296.13 EGB12530.1 - 0.29 11.0 2.8 16 5.5 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF448) CdiI_3 PF18616.1 EGB12530.1 - 2 8.3 3.8 30 4.6 0.1 3.6 4 0 0 4 4 4 0 CDI immunity proteins PATR PF12951.7 EGB12530.1 - 2.2 8.5 6.7 5 7.3 0.0 4.0 5 0 0 5 5 5 0 Passenger-associated-transport-repeat DUF3048_C PF17479.2 EGB12530.1 - 2.9 8.3 26.9 19 5.7 0.2 6.5 1 1 6 7 7 7 0 Protein of unknown function (DUF3048) C-terminal domain TRAM_LAG1_CLN8 PF03798.16 EGB12531.1 - 7e-13 48.8 9.1 1e-12 48.2 9.1 1.2 1 0 0 1 1 1 1 TLC domain BING4CT PF08149.11 EGB12532.1 - 5.3e-29 99.8 0.0 1.9e-26 91.7 0.0 3.3 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 EGB12532.1 - 1.3e-06 29.0 0.4 0.00015 22.5 0.3 4.1 3 2 1 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12532.1 - 0.0052 17.0 0.0 2.8 8.3 0.0 3.7 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Flu_B_NS1 PF02942.14 EGB12532.1 - 0.022 13.8 0.5 0.037 13.1 0.5 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) Cytochrom_D1 PF02239.16 EGB12532.1 - 0.025 13.1 0.0 1.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain GST_N_3 PF13417.6 EGB12533.1 - 2.7e-14 53.3 0.0 5.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB12533.1 - 3e-12 46.7 0.0 1.4e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EGB12533.1 - 2.3e-10 41.0 0.1 1.5e-07 32.0 0.0 2.3 1 1 1 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB12533.1 - 5.5e-09 36.3 0.0 1.4e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB12533.1 - 0.00029 20.8 0.2 0.00077 19.4 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGB12533.1 - 0.0098 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Ion_trans PF00520.31 EGB12534.1 - 7.8e-12 44.9 1.1 1.2e-11 44.3 1.1 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGB12534.1 - 0.00016 21.7 0.0 0.00052 20.0 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain GLTP PF08718.11 EGB12534.1 - 0.0083 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Pet127 PF08634.10 EGB12534.1 - 0.032 13.7 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet127 PX PF00787.24 EGB12535.1 - 0.00018 21.5 0.1 0.00077 19.4 0.0 2.0 2 0 0 2 2 2 1 PX domain DUF445 PF04286.12 EGB12536.1 - 7.4e-08 32.6 0.5 1.4e-06 28.4 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF445) ABC_tran PF00005.27 EGB12537.1 - 3.7e-08 34.0 0.0 4.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGB12537.1 - 0.0064 16.3 0.0 0.008 16.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGB12537.1 - 0.045 14.0 0.1 0.81 10.0 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit HSF_DNA-bind PF00447.17 EGB12538.1 - 1.4e-08 35.2 0.0 2.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4672 PF15716.5 EGB12538.1 - 4.8 6.8 7.7 2.7 7.6 4.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) Glycos_transf_1 PF00534.20 EGB12539.1 - 4.2e-11 42.7 0.0 7.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGB12539.1 - 1.4e-09 38.5 0.0 3.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peripla_BP_4 PF13407.6 EGB12539.1 - 0.013 15.1 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein domain DUF454 PF04304.13 EGB12539.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF454) Aldo_ket_red PF00248.21 EGB12540.1 - 1.6e-34 119.5 0.0 2.4e-32 112.3 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 EGB12541.1 - 9.3e-49 166.1 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12541.1 - 4.7e-34 117.8 0.0 6.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB12541.1 - 1.5e-05 24.0 0.0 2.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGB12541.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB12541.1 - 0.0026 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB12541.1 - 0.18 11.7 6.4 0.035 14.0 1.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 EGB12542.1 - 3.2e-09 37.6 0.0 4.7e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB12542.1 - 0.6 10.3 1.8 1.1 9.4 1.8 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Cyt-b5 PF00173.28 EGB12545.1 - 2.6e-17 62.7 0.0 2.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 EGB12546.1 - 9.6e-24 84.1 0.0 1.1e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGB12546.1 - 0.032 14.4 0.0 6.9 6.8 0.1 2.1 1 1 1 2 2 2 0 Ferric reductase NAD binding domain MatE PF01554.18 EGB12547.1 - 3.5e-28 98.3 15.5 7e-20 71.3 0.7 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGB12547.1 - 1.4e-09 38.2 5.0 1.4e-09 38.2 5.0 3.3 3 0 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 EGB12547.1 - 2e-07 30.0 6.5 2e-07 30.0 6.5 2.2 2 0 0 2 2 2 1 Lipid II flippase MurJ SLATT_fungal PF18142.1 EGB12547.1 - 0.059 13.4 0.1 0.059 13.4 0.1 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain DUF3648 PF12364.8 EGB12547.1 - 0.32 11.2 2.6 1 9.6 2.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) Exostosin PF03016.15 EGB12548.1 - 1.2e-11 44.4 0.0 1.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Sel1 PF08238.12 EGB12549.1 - 1.8e-84 276.2 64.1 5.8e-09 36.3 0.3 17.0 16 2 0 16 16 16 15 Sel1 repeat DUF410 PF04190.13 EGB12549.1 - 2.1e-05 24.4 7.5 2.1 8.1 0.1 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF410) AAA_lid_10 PF17872.1 EGB12549.1 - 4.9e-05 23.4 0.4 12 6.2 0.0 4.3 4 0 0 4 4 4 0 AAA lid domain TPR_1 PF00515.28 EGB12549.1 - 0.00011 21.9 31.1 0.063 13.1 1.3 9.1 8 0 0 8 8 7 2 Tetratricopeptide repeat Rubrerythrin PF02915.17 EGB12549.1 - 0.00011 22.7 5.1 0.026 14.9 0.3 3.2 3 0 0 3 3 3 2 Rubrerythrin TPR_10 PF13374.6 EGB12549.1 - 0.0014 18.4 29.6 0.016 15.0 0.7 9.1 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB12549.1 - 0.0017 18.6 33.5 0.077 13.3 0.8 8.5 9 3 3 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB12549.1 - 0.013 16.1 50.6 0.018 15.7 3.0 10.2 11 1 1 12 12 11 0 Tetratricopeptide repeat LpxI_N PF17930.1 EGB12549.1 - 0.022 14.6 0.9 0.53 10.2 0.0 3.2 4 0 0 4 4 4 0 LpxI N-terminal domain RHH_1 PF01402.21 EGB12549.1 - 0.051 13.5 7.3 11 6.1 0.0 4.7 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family B12-binding_2 PF02607.17 EGB12549.1 - 0.063 13.7 2.1 1.3e+02 3.1 0.0 4.6 4 0 0 4 4 4 0 B12 binding domain Flu_M1_C PF08289.11 EGB12549.1 - 0.086 13.1 0.2 8.6 6.7 0.0 3.0 3 0 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain Ferritin PF00210.24 EGB12549.1 - 0.12 12.3 0.9 24 4.9 0.0 3.0 3 0 0 3 3 3 0 Ferritin-like domain YicC_N PF03755.13 EGB12549.1 - 0.26 11.7 2.1 80 3.7 0.0 3.7 4 0 0 4 4 4 0 YicC-like family, N-terminal region TPR_8 PF13181.6 EGB12549.1 - 0.83 10.0 20.7 8.8 6.8 0.6 7.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Nop53 PF07767.11 EGB12549.1 - 3.8 6.8 5.2 24 4.2 0.1 3.4 4 0 0 4 4 4 0 Nop53 (60S ribosomal biogenesis) NSF PF02071.20 EGB12549.1 - 5.2 8.3 8.6 6.2e+02 2.1 0.0 6.5 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat ANAPC3 PF12895.7 EGB12549.1 - 8.3 6.7 16.6 19 5.5 0.5 5.8 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 3HCDH_N PF02737.18 EGB12550.1 - 2.6e-50 170.8 0.1 5.4e-50 169.8 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EGB12550.1 - 6.9e-34 117.3 0.1 1.1e-33 116.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 EGB12550.1 - 1e-30 106.2 0.7 5e-22 78.3 0.1 4.0 4 1 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 EGB12550.1 - 8.2e-23 81.4 0.0 1.2e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 EGB12550.1 - 0.12 12.5 0.7 0.38 10.9 0.7 2.0 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pro_isomerase PF00160.21 EGB12551.1 - 5.1e-33 114.6 0.0 5.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-actin_cap_A PF01267.17 EGB12554.1 - 3e-56 190.8 0.0 2.3e-38 132.2 0.0 2.0 2 0 0 2 2 2 2 F-actin capping protein alpha subunit Mito_carr PF00153.27 EGB12555.1 - 3.5e-24 84.5 0.4 1.7e-10 40.7 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein 2H-phosphodiest PF08975.10 EGB12555.1 - 0.044 13.7 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Pro_isomerase PF00160.21 EGB12556.1 - 8.8e-39 133.3 0.0 1e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNF2_N PF00176.23 EGB12557.1 - 7.2e-24 84.1 0.0 8e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGB12558.1 - 2.6e-08 34.2 0.1 3.4e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pepdidase_M14_N PF18027.1 EGB12559.1 - 1.4e-35 121.9 0.5 2e-35 121.4 0.5 1.3 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 EGB12559.1 - 3.2e-14 53.4 0.0 5.6e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase CHAD PF05235.14 EGB12559.1 - 0.066 13.2 0.5 0.64 10.0 0.7 2.0 2 0 0 2 2 2 0 CHAD domain Med26 PF08711.11 EGB12559.1 - 0.1 12.6 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Methyltransf_25 PF13649.6 EGB12560.1 - 1.3e-05 25.8 0.2 2.5e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGB12560.1 - 0.0075 15.6 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 EGB12560.1 - 0.096 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 EGB12560.1 - 0.14 11.7 0.4 0.26 10.8 0.4 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EGB12560.1 - 0.18 11.7 0.1 0.26 11.2 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGB12560.1 - 0.5 9.7 2.0 0.81 9.0 2.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EF-hand_8 PF13833.6 EGB12561.1 - 1.8e-14 53.3 1.8 2.7e-07 30.3 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 EGB12561.1 - 6.2e-13 49.0 5.6 8.6e-08 32.5 0.6 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB12561.1 - 7.1e-11 40.9 4.1 0.0046 16.4 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGB12561.1 - 4.7e-09 35.4 4.7 0.032 14.1 0.4 4.9 4 2 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGB12561.1 - 0.0083 15.6 1.2 0.25 10.9 0.0 3.7 4 0 0 4 4 4 1 EF hand IF2_N PF04760.15 EGB12561.1 - 0.14 12.0 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region SMC_N PF02463.19 EGB12562.1 - 2.6e-50 170.9 0.0 3.6e-34 118.1 0.0 2.0 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGB12562.1 - 4.5e-26 91.5 0.1 4.5e-26 91.5 0.1 2.4 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGB12562.1 - 4.9e-11 43.5 0.3 1.5e-10 42.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGB12562.1 - 1.1e-08 35.3 0.0 5.3e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGB12562.1 - 2.3e-07 30.5 0.0 5.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EGB12562.1 - 2.4e-06 27.5 0.0 3.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 EGB12562.1 - 0.0026 17.4 0.1 0.0026 17.4 0.1 4.2 4 1 1 5 5 5 1 AAA domain ABC_tran PF00005.27 EGB12562.1 - 0.0037 17.8 0.0 0.47 11.0 0.0 2.7 2 0 0 2 2 2 1 ABC transporter FmdE PF02663.14 EGB12562.1 - 0.016 15.2 0.0 0.061 13.4 0.0 2.0 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon MukB PF04310.12 EGB12562.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 MukB N-terminal TIM PF00121.18 EGB12563.1 - 1.4e-71 240.8 0.0 1.5e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Synaptobrevin PF00957.21 EGB12564.1 - 2.2e-20 72.2 0.2 2.3e-20 72.2 0.2 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2937 PF11157.8 EGB12564.1 - 0.0047 16.7 0.1 0.0048 16.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Nsp1_C PF05064.13 EGB12564.1 - 0.016 15.0 1.3 0.32 10.8 0.2 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region MtrB PF05440.12 EGB12564.1 - 0.052 14.0 1.1 1.5 9.3 1.1 2.0 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Sulfate_transp PF00916.20 EGB12565.1 - 6.4e-15 54.8 2.9 6.8e-15 54.7 2.9 1.0 1 0 0 1 1 1 1 Sulfate permease family UQ_con PF00179.26 EGB12566.1 - 3.7e-36 123.9 0.0 4e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGB12566.1 - 0.00037 20.2 0.0 0.00047 19.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Vps36-NZF-N PF16988.5 EGB12566.1 - 0.097 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Peptidase_M16 PF00675.20 EGB12567.1 - 1.2e-35 122.7 0.0 1.3e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) UPF0126 PF03458.13 EGB12568.1 - 8.6e-44 147.3 20.0 7.6e-25 86.6 7.9 2.6 2 1 0 2 2 2 2 UPF0126 domain PolyA_pol PF01743.20 EGB12568.1 - 0.02 15.3 0.0 0.97 9.9 0.0 2.1 2 0 0 2 2 2 0 Poly A polymerase head domain zf-UBP PF02148.19 EGB12569.1 - 9.2e-14 51.5 1.2 1.2e-13 51.2 1.2 1.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 EGB12569.1 - 0.068 12.9 0.8 0.13 12.0 0.5 1.6 1 1 1 2 2 2 0 Variant UBP zinc finger Dicty_CAR PF05462.11 EGB12570.1 - 3.4e-12 46.1 0.7 3.8e-12 45.9 0.7 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGB12570.1 - 2.9e-09 36.6 1.3 3.3e-09 36.4 1.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 EGB12570.1 - 4e-05 23.1 3.0 5.9e-05 22.5 3.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EGB12570.1 - 0.019 14.7 6.3 0.08 12.7 1.8 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 EGB12570.1 - 0.053 12.6 2.5 0.086 11.9 2.5 1.4 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region CopD PF05425.13 EGB12570.1 - 0.41 11.1 8.2 0.71 10.3 2.4 3.3 2 1 1 3 3 3 0 Copper resistance protein D TLC PF03219.14 EGB12571.1 - 5.8e-20 71.5 15.2 4.6e-16 58.6 15.2 3.5 1 1 0 1 1 1 1 TLC ATP/ADP transporter DnaJ PF00226.31 EGB12572.1 - 2.9e-12 46.5 0.0 6.7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2 PF00096.26 EGB12572.1 - 0.00017 21.8 1.8 0.00017 21.8 1.8 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGB12572.1 - 0.022 15.6 1.0 0.022 15.6 1.0 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger C1_2 PF03107.16 EGB12572.1 - 0.24 11.8 1.5 1 9.8 0.4 2.1 2 0 0 2 2 2 0 C1 domain zinc_ribbon_2 PF13240.6 EGB12572.1 - 4.7 7.1 6.8 1 9.2 2.7 1.9 2 0 0 2 2 2 0 zinc-ribbon domain PrmA PF06325.13 EGB12573.1 - 3.8e-42 144.7 0.0 4.1e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGB12573.1 - 1.1e-10 41.5 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGB12573.1 - 1.6e-08 35.1 0.0 2.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGB12573.1 - 5.2e-06 26.1 0.0 7.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGB12573.1 - 2.3e-05 24.9 0.0 3.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB12573.1 - 4.6e-05 23.3 0.0 5.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGB12573.1 - 0.016 15.0 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EGB12573.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 EGB12573.1 - 0.039 13.9 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 EGB12573.1 - 0.21 11.0 0.2 0.3 10.5 0.2 1.1 1 0 0 1 1 1 0 RRNA methyltransferase AviRa LRR_8 PF13855.6 EGB12574.1 - 1.7e-34 117.4 50.0 1.2e-08 34.6 4.6 7.7 2 2 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EGB12574.1 - 2.1e-27 94.7 51.1 7.3e-05 23.1 0.3 9.2 5 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGB12574.1 - 8.8e-08 31.7 45.1 0.46 11.2 0.1 12.8 12 1 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.6 EGB12574.1 - 2.6e-06 27.1 18.0 0.0053 16.3 2.9 4.5 1 1 5 6 6 6 6 Leucine-rich repeat zf-DNL PF05180.12 EGB12575.1 - 3.8e-29 100.4 0.2 4.2e-29 100.3 0.2 1.0 1 0 0 1 1 1 1 DNL zinc finger Zn_ribbon_SprT PF17283.2 EGB12575.1 - 0.0073 16.2 1.4 0.37 10.7 0.1 2.2 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Baculo_p33 PF05214.12 EGB12575.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P33 zf-TFIIB PF13453.6 EGB12575.1 - 0.1 11.9 1.1 0.21 10.9 1.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 EGB12575.1 - 0.6 10.1 4.0 4.2 7.4 4.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Acyl-CoA_dh_1 PF00441.24 EGB12576.1 - 3.2e-43 147.5 0.5 5e-43 146.9 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGB12576.1 - 1.9e-28 98.5 0.0 3.6e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGB12576.1 - 1.8e-23 83.3 0.2 7.1e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGB12576.1 - 7.8e-21 74.8 0.0 1.3e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CS PF04969.16 EGB12577.1 - 1.6e-07 32.2 0.0 3.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 CS domain Pkinase PF00069.25 EGB12578.1 - 8.8e-51 172.8 0.0 9.9e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12578.1 - 2.2e-27 96.0 0.0 2.7e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB12578.1 - 0.00021 20.7 0.0 0.0016 17.8 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGB12578.1 - 0.023 14.6 0.1 0.85 9.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 EGB12579.1 - 3.3e-23 82.1 0.0 4.2e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 ABC1 family Acyl-CoA_dh_1 PF00441.24 EGB12580.1 - 6.3e-32 110.9 4.3 1.4e-31 109.7 4.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGB12580.1 - 1.5e-19 69.9 0.0 3.6e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGB12580.1 - 3.9e-12 46.8 0.2 1.8e-11 44.7 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGB12580.1 - 6e-12 46.0 7.0 6e-12 46.0 7.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGB12580.1 - 0.051 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal CRAL_TRIO PF00650.20 EGB12581.1 - 1e-26 93.6 0.0 1.3e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGB12581.1 - 2.4e-06 27.6 0.2 5.1e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGB12581.1 - 0.00027 21.1 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HGTP_anticodon PF03129.20 EGB12582.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain PX PF00787.24 EGB12583.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.7 1 1 0 1 1 1 0 PX domain Ank_5 PF13857.6 EGB12584.1 - 2.1e-13 50.2 2.1 1.1e-07 32.0 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB12584.1 - 8.7e-11 42.1 0.3 6.8e-08 32.9 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGB12584.1 - 4.7e-10 39.9 0.1 8.9e-10 39.0 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGB12584.1 - 6.4e-10 39.0 0.1 7e-05 23.1 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGB12584.1 - 6.3e-09 35.4 0.0 0.0029 18.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat DUF3718 PF12514.8 EGB12584.1 - 0.022 14.9 0.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) MAPEG PF01124.18 EGB12585.1 - 7.6e-09 35.6 8.5 1.2e-08 35.0 8.5 1.3 1 0 0 1 1 1 1 MAPEG family SAT PF16073.5 EGB12585.1 - 0.18 11.5 0.8 0.27 10.9 0.8 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis EF-hand_1 PF00036.32 EGB12586.1 - 4.3e-26 88.5 1.2 8.9e-06 24.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB12586.1 - 5.3e-24 84.5 0.7 1.8e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB12586.1 - 9.1e-21 72.0 1.8 7.7e-06 25.4 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB12586.1 - 2.8e-20 70.9 6.4 6.4e-05 22.3 0.0 4.4 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB12586.1 - 1.2e-17 63.5 3.6 1.3e-08 34.5 0.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 EGB12586.1 - 2e-09 37.3 2.4 0.0004 20.3 0.5 3.0 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB12586.1 - 2e-05 24.9 0.1 0.0088 16.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGB12586.1 - 0.00032 20.5 8.8 5 7.1 0.0 4.5 4 1 1 5 5 5 2 EF hand EF-hand_9 PF14658.6 EGB12586.1 - 0.003 17.9 0.1 0.42 11.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain TerB PF05099.13 EGB12586.1 - 0.012 15.6 4.2 0.046 13.7 0.4 2.7 2 1 1 3 3 3 0 Tellurite resistance protein TerB VCBS PF13517.6 EGB12586.1 - 0.026 15.1 0.0 1.2 9.8 0.1 2.6 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Peptidase_M2 PF01401.18 EGB12586.1 - 0.034 12.8 0.1 0.036 12.7 0.1 1.0 1 0 0 1 1 1 0 Angiotensin-converting enzyme DUF5580 PF17743.1 EGB12586.1 - 0.047 12.2 0.0 0.25 9.9 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Phycoerythr_ab PF02972.14 EGB12586.1 - 0.099 12.5 0.3 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain Clathrin PF00637.20 EGB12587.1 - 0.00037 20.4 0.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 EGB12587.1 - 0.0026 18.6 2.7 0.019 15.8 0.9 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12587.1 - 0.051 13.9 0.0 0.58 10.5 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-MYND PF01753.18 EGB12588.1 - 4.2e-09 36.3 17.2 4.2e-09 36.3 17.2 2.0 2 0 0 2 2 2 1 MYND finger NIF PF03031.18 EGB12589.1 - 2.6e-11 43.5 0.0 3.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EGB12589.1 - 0.077 13.4 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 EGB12590.1 - 2.9e-40 136.1 9.6 4.9e-17 61.6 0.0 4.8 2 2 2 4 4 4 4 Mitochondrial carrier protein GBP PF02263.19 EGB12591.1 - 1.6e-63 214.4 0.0 1.9e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain SpoU_methylase PF00588.19 EGB12592.1 - 4.1e-20 72.4 0.0 4.8e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family CN_hydrolase PF00795.22 EGB12593.1 - 9e-48 162.9 0.1 1.1e-47 162.6 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SLBP_RNA_bind PF15247.6 EGB12594.1 - 7.9e-30 102.8 4.6 8.7e-30 102.7 4.6 1.0 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain ABM PF03992.16 EGB12595.1 - 1e-11 44.8 0.0 1.1e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MFS_3 PF05977.13 EGB12595.1 - 0.052 11.9 0.0 0.053 11.9 0.0 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector RRM_1 PF00076.22 EGB12596.1 - 1.8e-27 94.9 0.0 1.6e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB12596.1 - 8.5e-09 35.4 0.2 0.0058 16.7 0.0 2.5 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGB12596.1 - 1.2e-05 25.2 0.0 0.04 13.9 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PRP38 PF03371.15 EGB12597.1 - 2.3e-35 122.0 0.0 2.6e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 PRP38 family FYVE PF01363.21 EGB12598.1 - 2.8e-11 43.4 5.6 3.3e-11 43.2 5.6 1.1 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.7 EGB12598.1 - 0.85 9.7 9.1 12 6.0 9.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 EGB12599.1 - 1.3e-10 41.3 13.8 1.7e-10 40.9 13.8 1.2 1 0 0 1 1 1 1 FYVE zinc finger Dynamin_N PF00350.23 EGB12600.1 - 1.9e-30 106.1 0.0 2.6e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGB12600.1 - 2.1e-28 99.4 0.0 2.6e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EGB12600.1 - 7.5e-06 26.0 0.2 0.0063 16.6 0.1 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGB12601.1 - 0.0037 17.5 0.3 0.0083 16.4 0.3 1.6 1 1 1 2 2 2 1 AAA domain SRP54 PF00448.22 EGB12601.1 - 0.018 14.6 1.0 0.036 13.7 0.4 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EGB12601.1 - 0.035 13.8 1.2 0.037 13.7 0.2 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGB12601.1 - 0.045 13.9 0.2 0.079 13.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 EGB12601.1 - 0.1 11.2 0.3 0.16 10.6 0.3 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase FKBP_C PF00254.28 EGB12602.1 - 3.6e-09 36.8 0.0 4.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHO4 PF01384.20 EGB12603.1 - 1.7e-111 372.6 12.9 1.7e-111 372.6 12.9 1.7 2 0 0 2 2 2 1 Phosphate transporter family BTB_2 PF02214.22 EGB12603.1 - 0.00079 19.7 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain EI24 PF07264.11 EGB12603.1 - 0.33 11.2 5.0 0.095 12.9 0.4 2.4 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) TPM_phosphatase PF04536.14 EGB12604.1 - 7.8e-06 26.1 0.0 8.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 TPM domain ubiquitin PF00240.23 EGB12606.1 - 1.1e-26 92.4 0.3 1.2e-26 92.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGB12606.1 - 4.7e-14 52.0 0.4 5.2e-14 51.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGB12606.1 - 0.00029 21.2 0.1 0.00031 21.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EGB12606.1 - 0.0011 19.4 0.0 0.0014 19.1 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGB12606.1 - 0.0055 16.7 0.2 1.6 8.8 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB12606.1 - 0.0074 16.4 0.1 0.014 15.5 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGB12606.1 - 0.023 14.6 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Mito_carr PF00153.27 EGB12607.1 - 2.1e-31 107.7 8.4 9.5e-13 47.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.22 EGB12608.1 - 1.5e-58 198.4 0.3 2e-58 198.1 0.3 1.1 1 0 0 1 1 1 1 Subtilase family DEAD_2 PF06733.15 EGB12609.1 - 3.6e-49 166.8 0.0 5.3e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 EGB12609.1 - 3e-42 144.7 0.0 4.9e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 EGB12609.1 - 9.5e-23 80.9 0.0 5.4e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EGB12609.1 - 1.5e-06 28.4 0.1 0.00012 22.1 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGB12609.1 - 0.012 15.4 0.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase Glycos_transf_2 PF00535.26 EGB12610.1 - 8.2e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4438 PF14505.6 EGB12610.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) Beta_elim_lyase PF01212.21 EGB12612.1 - 4.1e-07 29.6 0.1 4.5e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGB12612.1 - 0.0072 15.7 0.2 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGB12612.1 - 0.023 13.9 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Lyase_1 PF00206.20 EGB12613.1 - 1.1e-102 343.6 0.0 1.3e-102 343.4 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGB12613.1 - 6.5e-21 74.5 0.0 1.5e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus zf_CCCH_4 PF18345.1 EGB12614.1 - 3.3e-05 23.8 8.2 6.6e-05 22.8 8.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EGB12614.1 - 3.5e-05 23.6 4.0 7.4e-05 22.6 4.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NUDIX PF00293.28 EGB12614.1 - 6.6e-05 23.0 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Torus PF16131.5 EGB12614.1 - 0.00061 20.5 0.2 0.0014 19.3 0.2 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 EGB12614.1 - 0.0018 18.1 4.9 0.0035 17.1 4.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Borrelia_P83 PF05262.11 EGB12614.1 - 1.6 7.1 14.6 2.2 6.6 14.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mito_carr PF00153.27 EGB12615.1 - 5e-31 106.5 0.1 1e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein PLAC8 PF04749.17 EGB12616.1 - 3.6e-17 63.2 9.8 7.5e-17 62.2 9.8 1.6 1 0 0 1 1 1 1 PLAC8 family GlutR_N PF05201.15 EGB12616.1 - 6.9e-08 32.4 0.0 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 2 Glutamyl-tRNAGlu reductase, N-terminal domain GlutR_dimer PF00745.20 EGB12616.1 - 1.4 9.4 7.0 0.65 10.5 1.0 2.8 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain RPE65 PF03055.15 EGB12617.1 - 4.8e-90 303.0 0.0 5.5e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein EF-hand_7 PF13499.6 EGB12618.1 - 2.1e-20 72.9 10.5 1.8e-07 31.5 0.3 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGB12618.1 - 5.2e-19 66.3 14.1 0.0044 16.5 0.5 6.0 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 EGB12618.1 - 7.8e-19 65.9 12.4 0.0039 17.0 0.2 6.4 6 0 0 6 6 6 5 EF-hand domain WW PF00397.26 EGB12618.1 - 3.8e-18 65.3 34.1 3.6e-06 27.0 4.4 3.7 3 0 0 3 3 3 3 WW domain EF-hand_8 PF13833.6 EGB12618.1 - 4.5e-12 45.6 8.7 3.9e-06 26.6 1.2 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB12618.1 - 6.1e-11 41.3 18.3 0.0064 15.9 0.0 5.9 6 0 0 6 6 6 4 EF hand EF-hand_10 PF14788.6 EGB12618.1 - 0.00027 20.7 0.3 0.51 10.2 0.0 4.2 5 0 0 5 5 5 1 EF hand TPR_12 PF13424.6 EGB12618.1 - 0.0013 18.9 2.1 0.0013 18.9 2.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat SPARC_Ca_bdg PF10591.9 EGB12618.1 - 0.0016 18.7 0.6 1.5 9.1 0.0 3.4 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region YolD PF08863.10 EGB12618.1 - 0.12 12.4 4.2 6.4 6.9 0.2 3.3 4 0 0 4 4 4 0 YolD-like protein Ribosomal_L29 PF00831.23 EGB12618.1 - 1.4 8.9 5.5 2.8 8.0 0.2 3.1 2 1 0 2 2 2 0 Ribosomal L29 protein PQQ PF01011.21 EGB12618.1 - 2 8.5 9.2 1.3 9.1 0.9 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat Sulfatase PF00884.23 EGB12619.1 - 4.1e-49 167.6 0.1 5.5e-49 167.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase zf-MYND PF01753.18 EGB12619.1 - 5.6e-08 32.7 12.9 1.3e-07 31.5 12.9 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EGB12619.1 - 0.0001 22.1 7.7 0.00029 20.7 7.7 1.8 1 0 0 1 1 1 1 HIT zinc finger Phosphodiest PF01663.22 EGB12619.1 - 0.0011 18.7 0.0 0.086 12.4 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EGB12619.1 - 0.022 15.5 0.0 0.064 14.0 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 EGB12619.1 - 0.042 12.9 0.2 0.1 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) zf-C6H2 PF15801.5 EGB12619.1 - 0.7 10.2 5.4 1.5 9.2 5.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Gly_transf_sug PF04488.15 EGB12620.1 - 4.4e-10 40.1 0.0 9.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif CAP59_mtransfer PF11735.8 EGB12620.1 - 0.00017 21.4 0.3 0.00074 19.3 0.0 2.2 2 1 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Caps_synth PF05704.12 EGB12620.1 - 0.025 14.0 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Aldedh PF00171.22 EGB12621.1 - 2.2e-74 250.7 0.1 2.9e-74 250.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family REJ PF02010.15 EGB12622.1 - 2.6e-16 59.5 0.0 3.5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 REJ domain VCBS PF13517.6 EGB12622.1 - 6e-05 23.6 10.2 0.27 11.9 0.4 4.3 3 1 1 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RGI_lyase PF18370.1 EGB12622.1 - 0.0081 16.5 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Rhamnogalacturonan I lyases beta-sheet domain zf-TRAF PF02176.18 EGB12622.1 - 0.12 13.1 4.8 0.29 11.8 4.8 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger FG-GAP PF01839.23 EGB12622.1 - 3.6 7.8 16.1 9.7 6.4 0.0 4.7 4 0 0 4 4 4 0 FG-GAP repeat FA_desaturase PF00487.24 EGB12623.1 - 2.5e-17 63.6 6.8 7.4e-13 48.9 0.2 2.3 2 0 0 2 2 2 2 Fatty acid desaturase Y_phosphatase3 PF13350.6 EGB12625.1 - 3e-32 112.5 0.0 6.1e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family GST_N_3 PF13417.6 EGB12625.1 - 3.3e-15 56.3 0.0 7.1e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB12625.1 - 4.8e-10 39.6 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGB12625.1 - 1.6e-09 37.9 0.0 4e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGB12625.1 - 0.00048 20.1 0.1 0.00048 20.1 0.1 3.2 4 0 0 4 4 4 1 Glutathione S-transferase, C-terminal domain IQ PF00612.27 EGB12625.1 - 0.029 14.1 2.4 5.1 7.2 0.1 3.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif Myotub-related PF06602.14 EGB12625.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Redoxin PF08534.10 EGB12626.1 - 4.3e-15 55.7 0.0 5.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGB12626.1 - 0.0043 17.0 0.0 0.0047 16.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family CDKN3 PF05706.12 EGB12626.1 - 0.11 12.2 0.0 2.9 7.5 0.0 2.0 1 1 1 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) REJ PF02010.15 EGB12627.1 - 4.4e-39 134.5 0.0 2.7e-38 132.0 0.0 2.0 1 1 1 2 2 2 2 REJ domain Sulfotransfer_3 PF13469.6 EGB12628.1 - 0.0021 18.5 0.0 2.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Pkinase PF00069.25 EGB12629.1 - 1.1e-73 247.9 0.0 1.2e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12629.1 - 2.7e-43 148.2 0.0 3.2e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB12629.1 - 5e-07 29.3 0.0 2.7e-06 26.9 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGB12629.1 - 1e-06 28.9 0.0 2.4e-05 24.4 0.2 2.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB12629.1 - 4.4e-05 22.4 0.0 6.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGB12629.1 - 5.9e-05 22.2 0.0 7.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGB12629.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGB12629.1 - 0.0028 17.3 0.0 0.0048 16.5 0.0 1.5 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGB12629.1 - 0.0034 16.8 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGB12629.1 - 0.024 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 EGB12629.1 - 0.029 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UQ_con PF00179.26 EGB12630.1 - 2e-48 163.6 0.0 2.4e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 EGB12630.1 - 1.8e-09 37.3 0.8 2.8e-09 36.7 0.8 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 EGB12630.1 - 0.0035 17.1 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_3 PF09288.10 EGB12630.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain CUE PF02845.16 EGB12630.1 - 0.072 12.8 0.1 0.41 10.4 0.0 2.0 1 1 1 2 2 2 0 CUE domain RWD PF05773.22 EGB12630.1 - 0.098 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain WIYLD PF10440.9 EGB12630.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain DUF1296 PF06972.11 EGB12630.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) AAA_11 PF13086.6 EGB12631.1 - 2.6e-29 102.8 0.8 2.7e-15 56.9 1.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 EGB12631.1 - 4e-12 46.7 0.0 1.1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGB12631.1 - 3.4e-09 36.7 5.8 3.4e-09 36.7 5.8 3.3 3 1 0 3 3 3 1 AAA domain DUF2075 PF09848.9 EGB12631.1 - 0.00021 20.7 0.0 0.00037 19.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) EF-hand_5 PF13202.6 EGB12631.1 - 0.0051 16.2 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 EF hand AAA_22 PF13401.6 EGB12631.1 - 0.0074 16.6 0.1 0.086 13.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB12631.1 - 0.0081 16.6 0.4 0.0081 16.6 0.4 3.0 2 1 1 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGB12631.1 - 0.012 15.4 0.1 0.059 13.1 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF1326 PF07040.11 EGB12631.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) PhoH PF02562.16 EGB12631.1 - 0.018 14.5 0.0 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 EGB12631.1 - 0.019 14.5 0.0 4 6.9 0.0 2.4 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 EGB12631.1 - 0.049 13.4 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 EGB12631.1 - 0.091 12.8 0.0 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EGB12631.1 - 0.11 12.9 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TAT_signal PF10518.9 EGB12631.1 - 0.13 12.1 0.1 0.13 12.1 0.1 4.8 4 0 0 4 4 2 0 TAT (twin-arginine translocation) pathway signal sequence AAA_12 PF13087.6 EGB12632.1 - 1.9e-31 109.3 0.0 2.1e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGB12632.1 - 1.5e-05 24.7 0.0 3.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGB12632.1 - 0.031 14.0 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pep_deformylase PF01327.21 EGB12633.1 - 8.9e-43 145.6 0.0 1e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Kinesin PF00225.23 EGB12634.1 - 1.5e-68 231.2 0.0 1.8e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB12634.1 - 1.2e-18 67.5 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 EGB12634.1 - 0.0027 18.1 0.2 0.0045 17.4 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta2 PF13177.6 EGB12635.1 - 7.8e-12 45.3 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EGB12635.1 - 2.2e-08 34.4 0.1 4.6e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGB12635.1 - 2.6e-06 27.9 0.0 6.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGB12635.1 - 0.00079 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGB12635.1 - 0.0014 19.0 1.3 0.14 12.5 0.2 2.8 1 1 0 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.13 EGB12635.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGB12635.1 - 0.047 13.6 0.0 0.099 12.6 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 EGB12635.1 - 0.053 13.3 0.1 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGB12635.1 - 0.055 12.9 0.0 0.15 11.4 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB12635.1 - 0.092 12.7 0.1 0.23 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RRM_1 PF00076.22 EGB12636.1 - 1.8e-09 37.3 0.0 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1c PF00749.21 EGB12637.1 - 3.2e-93 312.1 0.0 4.4e-93 311.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGB12637.1 - 1.2e-38 132.8 0.0 1.8e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WD40 PF00400.32 EGB12638.1 - 2.3e-11 44.1 4.1 0.0046 17.8 0.0 6.2 6 1 0 6 6 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12638.1 - 5.8e-10 39.3 1.6 0.028 14.7 0.0 5.7 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGB12638.1 - 0.00054 19.1 0.0 0.0036 16.4 0.0 2.3 2 0 0 2 2 2 1 Coatomer WD associated region IKI3 PF04762.12 EGB12638.1 - 0.01 13.9 0.0 0.021 12.8 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Nbas_N PF15492.6 EGB12638.1 - 0.03 13.7 0.1 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 EGB12638.1 - 0.043 13.7 0.4 4.3 7.2 0.4 3.0 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.20 EGB12638.1 - 0.078 12.9 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS PPR PF01535.20 EGB12638.1 - 0.11 12.8 0.6 42 4.7 0.0 3.9 3 0 0 3 3 3 0 PPR repeat PBP_like PF12727.7 EGB12638.1 - 0.13 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain TRIQK PF15168.6 EGB12638.1 - 0.16 11.9 0.6 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family TPR_14 PF13428.6 EGB12638.1 - 9.5 7.3 16.1 6.5 7.9 0.3 5.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 EGB12639.1 - 1.8e-70 238.5 0.0 2e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB12639.1 - 5.4e-17 61.8 0.2 1.1e-16 60.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB12639.1 - 4.9e-10 39.5 0.0 0.00086 19.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB12639.1 - 2e-07 31.5 0.0 0.00078 20.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB12639.1 - 5.1e-07 29.2 0.1 7.2e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB12639.1 - 0.00014 20.8 0.2 0.02 13.6 0.5 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EGB12639.1 - 0.0039 16.6 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EGB12639.1 - 0.0053 15.6 0.0 0.17 10.6 0.0 2.0 2 0 0 2 2 2 1 MCRA family FAD_binding_2 PF00890.24 EGB12639.1 - 0.0054 15.9 2.3 0.036 13.1 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 EGB12639.1 - 0.015 13.7 0.1 0.025 13.0 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 EGB12639.1 - 0.05 12.8 0.3 0.081 12.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EGB12639.1 - 0.062 12.5 0.4 0.16 11.2 0.4 1.6 1 0 0 1 1 1 0 Thi4 family RabGAP-TBC PF00566.18 EGB12640.1 - 1.9e-39 135.5 0.0 3.1e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Amidase PF01425.21 EGB12641.1 - 2.6e-65 221.2 5.0 1.4e-64 218.8 5.0 2.0 1 1 0 1 1 1 1 Amidase SIMPL PF04402.14 EGB12641.1 - 0.28 11.6 1.2 1.8 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF541) FGE-sulfatase PF03781.16 EGB12642.1 - 3.4e-73 246.4 3.5 4e-73 246.2 3.5 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 S1 PF00575.23 EGB12643.1 - 5.2e-13 49.1 0.2 5.2e-13 49.1 0.2 1.9 2 0 0 2 2 2 1 S1 RNA binding domain SAPS PF04499.15 EGB12643.1 - 0.0011 17.8 0.1 0.0013 17.6 0.1 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein RNA_pol_Rpc4 PF05132.14 EGB12643.1 - 2.3 8.6 16.9 3.9 7.9 16.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RRM_1 PF00076.22 EGB12644.1 - 2.8e-14 52.7 0.1 1.1e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 EGB12644.1 - 2.4e-11 43.5 0.4 5.2e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Surp module RRM_5 PF13893.6 EGB12644.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB12644.1 - 0.086 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif Mito_carr PF00153.27 EGB12645.1 - 7.2e-40 134.8 5.4 6.3e-18 64.5 0.2 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2046 PF09755.9 EGB12646.1 - 0.11 11.8 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) XPG_N PF00752.17 EGB12647.1 - 2.5e-28 98.5 0.0 3.6e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGB12647.1 - 1.1e-24 86.6 0.1 2e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EGB12647.1 - 0.0023 17.4 0.1 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 XPG domain containing HMG_box PF00505.19 EGB12648.1 - 2.7e-19 69.4 0.0 3.1e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGB12648.1 - 1.6e-15 57.5 0.0 1.8e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain DUF736 PF05284.12 EGB12648.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF736) PNRC PF15365.6 EGB12649.1 - 3.8e-05 23.4 2.1 3.8e-05 23.4 2.1 2.7 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif Herpes_DNAp_acc PF04929.12 EGB12649.1 - 8.4 5.2 9.8 8.7 5.2 9.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Porin_3 PF01459.22 EGB12650.1 - 2.4e-33 115.8 0.3 2.6e-33 115.6 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Histone_H2A_C PF16211.5 EGB12653.1 - 8.3e-20 70.2 1.4 2e-19 69.0 1.4 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGB12653.1 - 5.1e-12 46.3 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB12653.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB12654.1 - 6.1e-53 178.7 1.1 6.8e-53 178.5 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGB12654.1 - 0.00076 20.1 3.0 0.00098 19.7 3.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGB12654.1 - 0.00088 19.4 0.3 0.0014 18.7 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB12654.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGB12654.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGB12654.1 - 0.032 14.3 0.1 0.057 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit LSM PF01423.22 EGB12655.1 - 1.1e-11 44.2 0.0 2.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 LSM domain Glyco_transf_41 PF13844.6 EGB12657.1 - 2.4e-07 29.6 0.0 5.1e-07 28.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 41 Abhydrolase_1 PF00561.20 EGB12658.1 - 3.6e-34 118.6 0.1 4.6e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGB12658.1 - 8e-06 26.6 5.1 8e-06 26.6 5.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGB12658.1 - 0.00099 19.2 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein NTF2 PF02136.20 EGB12659.1 - 1.4e-17 64.3 0.0 1.6e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain AAA PF00004.29 EGB12660.1 - 1.5e-42 145.1 0.0 2.9e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 EGB12660.1 - 1.2e-19 70.1 1.3 2.8e-19 69.0 1.3 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 EGB12660.1 - 1.4e-16 60.2 0.9 4.8e-16 58.5 0.1 2.4 3 1 0 3 3 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EGB12660.1 - 1.2e-07 31.4 0.0 3.2e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGB12660.1 - 2.2e-06 27.5 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGB12660.1 - 2.6e-06 27.9 0.1 0.0002 21.8 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGB12660.1 - 4e-06 26.9 0.0 3e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGB12660.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGB12660.1 - 6.6e-05 23.2 0.1 0.0055 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGB12660.1 - 8.7e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EGB12660.1 - 0.00015 21.8 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB12660.1 - 0.00033 20.3 0.4 0.17 11.5 0.1 3.2 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 EGB12660.1 - 0.00046 19.5 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 EGB12660.1 - 0.00069 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGB12660.1 - 0.00094 19.4 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGB12660.1 - 0.0038 17.6 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB12660.1 - 0.0039 17.7 0.0 0.0083 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGB12660.1 - 0.0051 17.2 0.0 0.026 14.9 0.0 2.2 1 1 1 2 2 2 1 RNA helicase AAA_24 PF13479.6 EGB12660.1 - 0.01 15.6 0.1 0.048 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGB12660.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TAtT PF16811.5 EGB12660.1 - 0.024 14.0 0.8 0.035 13.4 0.8 1.2 1 0 0 1 1 1 0 TRAP transporter T-component USP8_dimer PF08969.11 EGB12660.1 - 0.031 14.4 0.9 0.067 13.4 0.9 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_7 PF12775.7 EGB12660.1 - 0.035 13.6 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 EGB12660.1 - 0.045 13.6 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 EGB12660.1 - 0.048 13.4 0.0 0.41 10.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2791 PF10923.8 EGB12660.1 - 0.053 12.4 0.0 0.15 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.12 EGB12660.1 - 0.061 13.2 0.0 0.91 9.4 0.0 2.3 1 1 1 2 2 2 0 NACHT domain TPR_1 PF00515.28 EGB12660.1 - 0.067 13.0 0.7 0.15 11.9 0.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Parvo_NS1 PF01057.17 EGB12660.1 - 0.083 12.0 0.1 0.84 8.7 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TPR_7 PF13176.6 EGB12660.1 - 0.16 12.0 0.8 0.42 10.7 0.1 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat Use1 PF09753.9 EGB12660.1 - 0.26 11.0 1.2 0.41 10.3 0.6 1.6 2 0 0 2 2 2 0 Membrane fusion protein Use1 TPR_2 PF07719.17 EGB12660.1 - 0.41 10.9 2.1 0.48 10.7 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 EGB12661.1 - 3.6e-12 47.2 0.2 6.5e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EGB12661.1 - 0.011 16.4 0.9 0.021 15.5 0.9 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain PA PF02225.22 EGB12661.1 - 0.034 14.2 0.1 0.082 12.9 0.1 1.7 1 0 0 1 1 1 0 PA domain Thioredoxin PF00085.20 EGB12662.1 - 6.5e-12 45.3 0.1 7e-12 45.2 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 EGB12662.1 - 0.16 12.1 0.1 0.18 12.0 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin Evr1_Alr PF04777.13 EGB12663.1 - 7.2e-19 68.1 0.3 8e-19 68.0 0.3 1.0 1 0 0 1 1 1 1 Erv1 / Alr family Chloroa_b-bind PF00504.21 EGB12664.1 - 1.6e-26 93.7 0.0 2.3e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EF-hand_7 PF13499.6 EGB12666.1 - 5.3e-17 62.0 0.6 5.7e-17 61.9 0.6 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB12666.1 - 1.7e-16 58.5 0.7 7e-09 34.6 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB12666.1 - 9.5e-14 50.1 0.3 2.9e-06 26.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGB12666.1 - 1.9e-12 46.8 1.9 4.8e-09 35.9 1.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB12666.1 - 1.8e-11 43.0 0.6 2.5e-05 23.6 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGB12666.1 - 1.5e-05 25.2 0.0 1.9e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EGB12666.1 - 0.00057 19.8 0.1 0.00096 19.1 0.1 1.4 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EGB12666.1 - 0.0053 16.7 0.0 1.2 9.1 0.0 2.0 1 1 1 2 2 2 2 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGB12666.1 - 0.0059 16.9 0.0 0.0067 16.7 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGB12666.1 - 0.035 13.9 0.9 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 EF hand Na_Ca_ex PF01699.24 EGB12667.1 - 9.1e-08 32.2 13.2 1e-07 32.0 13.2 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF3460 PF11943.8 EGB12668.1 - 0.0011 19.2 0.2 0.0027 18.0 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3460) DnaJ PF00226.31 EGB12669.1 - 9.5e-19 67.3 0.2 1.1e-18 67.1 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain GDP_Man_Dehyd PF16363.5 EGB12670.1 - 1.3e-52 179.3 0.0 2.5e-52 178.3 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGB12670.1 - 8.8e-51 172.7 0.0 1.3e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGB12670.1 - 5.1e-16 58.7 0.0 3.1e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGB12670.1 - 2.3e-11 43.2 0.0 3.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGB12670.1 - 1.6e-10 40.6 0.0 2.5e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGB12670.1 - 0.0035 16.5 0.2 0.021 14.0 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EGB12670.1 - 0.036 14.0 0.0 0.092 12.7 0.0 1.7 2 0 0 2 2 2 0 KR domain Cullin PF00888.22 EGB12671.1 - 7.5e-170 566.6 1.0 9.7e-170 566.2 1.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGB12671.1 - 3.2e-25 87.9 1.0 1e-24 86.3 0.3 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Pkinase PF00069.25 EGB12672.1 - 1.5e-50 172.1 0.0 1e-49 169.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12672.1 - 1.5e-24 86.7 0.0 2e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB12672.1 - 0.0016 18.4 0.1 0.021 14.7 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family ABC1 PF03109.16 EGB12672.1 - 0.044 13.9 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC1 family WWE PF02825.20 EGB12673.1 - 2.9e-29 101.5 0.0 1.1e-11 45.2 0.0 3.3 3 0 0 3 3 3 3 WWE domain Mem_trans PF03547.18 EGB12673.1 - 1.8e-07 29.9 12.3 3.5e-07 29.0 0.2 2.3 2 0 0 2 2 2 2 Membrane transport protein GRDP-like PF07173.12 EGB12673.1 - 0.0042 17.8 0.0 0.0063 17.2 0.0 1.3 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like TCR PF03638.15 EGB12674.1 - 1.7e-20 73.0 66.0 1.4e-11 44.5 22.1 3.0 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.7 EGB12674.1 - 0.00016 21.5 0.1 0.00036 20.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like MSL2-CXC PF16682.5 EGB12674.1 - 5.5 7.2 39.9 0.41 10.8 14.9 2.5 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Pkinase PF00069.25 EGB12675.1 - 1.9e-51 175.0 0.0 2.2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12675.1 - 1.8e-34 119.2 0.0 2e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB12675.1 - 4.2e-08 32.4 0.0 5.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGB12675.1 - 2.1e-06 27.9 0.0 0.0048 16.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB12675.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EGB12675.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EGB12675.1 - 0.23 11.1 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 EGB12676.1 - 6.9e-26 90.0 15.7 6.8e-08 33.1 0.6 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12676.1 - 5.1e-12 45.9 0.6 0.00031 21.0 0.0 4.8 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGB12676.1 - 6.6e-05 22.9 0.0 0.079 12.8 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGB12676.1 - 0.00074 18.6 0.2 0.63 8.9 0.1 2.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Isochorismatase PF00857.20 EGB12677.1 - 8.8e-30 104.2 0.5 1.1e-29 103.9 0.5 1.1 1 0 0 1 1 1 1 Isochorismatase family AMP-binding PF00501.28 EGB12678.1 - 2e-79 267.2 0.3 2.5e-79 266.9 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB12678.1 - 6.1e-18 65.6 1.2 2e-17 63.9 0.3 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 EGB12679.1 - 3.3e-46 157.9 6.3 3.3e-46 157.9 6.3 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB12679.1 - 6.8e-11 42.2 1.0 6.8e-11 42.2 1.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB12679.1 - 0.00034 20.0 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PARP PF00644.20 EGB12680.1 - 5.5e-28 97.9 0.1 3.3e-26 92.1 0.1 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PBP1_TM PF14812.6 EGB12681.1 - 3.5 8.1 8.8 0.23 11.8 0.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sulfatase PF00884.23 EGB12682.1 - 1.4e-50 172.5 0.0 1.7e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 EGB12682.1 - 0.012 16.3 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 EGB12682.1 - 0.057 13.0 0.1 1.7 8.2 0.1 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 EGB12682.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Polysacc_synt_C PF14667.6 EGB12683.1 - 7.5e-10 39.0 2.8 7.5e-10 39.0 2.8 2.5 1 1 2 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 EGB12683.1 - 2.3e-09 37.1 11.4 4e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 MatE SPC22 PF04573.12 EGB12684.1 - 9.2e-48 162.0 0.2 1e-47 161.8 0.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Phage_P2_GpE PF06528.12 EGB12684.1 - 0.11 12.0 0.3 0.42 10.2 0.1 2.1 2 0 0 2 2 2 0 Phage P2 GpE Abhydrolase_6 PF12697.7 EGB12685.1 - 5.8e-21 76.1 6.6 7.1e-21 75.8 6.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGB12685.1 - 3.5e-14 53.1 0.1 1.4e-11 44.5 0.1 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGB12685.1 - 3.6e-11 42.8 0.0 1.1e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGB12685.1 - 0.011 15.6 0.0 0.023 14.5 0.1 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGB12685.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PNP_UDP_1 PF01048.20 EGB12685.1 - 0.085 12.1 0.1 0.12 11.6 0.1 1.4 1 1 0 1 1 1 0 Phosphorylase superfamily Thioesterase PF00975.20 EGB12685.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DSPn PF14671.6 EGB12686.1 - 1.8e-42 145.1 0.0 7.7e-42 143.1 0.0 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGB12686.1 - 4.1e-13 49.3 0.0 7.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGB12686.1 - 0.0001 21.9 0.0 0.00024 20.7 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGB12686.1 - 0.05 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate NAD_binding_11 PF14833.6 EGB12688.1 - 0.044 14.0 0.6 0.57 10.4 0.2 2.7 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GST_C_3 PF14497.6 EGB12689.1 - 6.6e-12 45.5 0.0 1.2e-11 44.6 0.0 1.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB12689.1 - 8.4e-10 38.9 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB12689.1 - 0.0035 17.5 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB12689.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Jacalin PF01419.17 EGB12689.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Jacalin-like lectin domain GST_C_2 PF13410.6 EGB12689.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MORN PF02493.20 EGB12690.1 - 6.2e-81 261.7 82.4 3.9e-08 32.7 5.2 14.7 15 0 0 15 15 15 14 MORN repeat Ephrin_rec_like PF07699.13 EGB12693.1 - 7.6e-08 32.0 5.0 7.6e-08 32.0 5.0 3.6 2 1 1 3 3 3 2 Putative ephrin-receptor like EGF_2 PF07974.13 EGB12693.1 - 0.0091 16.3 12.0 0.0091 16.3 12.0 5.6 7 0 0 7 7 7 2 EGF-like domain Sp38 PF07354.12 EGB12693.1 - 0.15 11.5 4.8 0.41 10.0 4.8 1.7 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Ank_2 PF12796.7 EGB12694.1 - 9.2e-20 71.0 2.7 1.7e-11 44.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB12694.1 - 3.6e-16 59.3 1.2 1.2e-06 29.0 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB12694.1 - 1.6e-15 56.7 10.1 2e-06 28.0 0.4 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EGB12694.1 - 2.5e-14 52.0 3.8 0.00021 21.4 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGB12694.1 - 2e-13 50.3 8.7 4.4e-08 33.2 0.2 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Thioredoxin PF00085.20 EGB12694.1 - 1.2e-10 41.3 0.2 4.6e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin EF-hand_7 PF13499.6 EGB12694.1 - 3.2e-05 24.3 0.7 7e-05 23.2 0.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair Na_Ca_ex PF01699.24 EGB12695.1 - 5.3e-05 23.2 8.2 6.8e-05 22.9 8.2 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein NDUF_B6 PF09782.9 EGB12695.1 - 0.14 12.2 0.9 0.19 11.8 0.9 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Snf7 PF03357.21 EGB12696.1 - 4.4e-40 137.1 14.8 5.8e-40 136.7 14.8 1.1 1 0 0 1 1 1 1 Snf7 DUF3043 PF11241.8 EGB12696.1 - 0.19 11.7 4.8 0.24 11.4 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) YlqD PF11068.8 EGB12696.1 - 1.5 9.2 13.5 0.3 11.5 1.9 2.2 1 1 0 2 2 2 0 YlqD protein DnaJ-X PF14308.6 EGB12696.1 - 3.3 7.1 13.1 0.13 11.7 6.8 1.9 2 1 0 2 2 2 0 X-domain of DnaJ-containing Hist_deacetyl PF00850.19 EGB12697.1 - 1.8e-70 237.8 0.6 2.3e-70 237.5 0.6 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Hist_deacetyl PF00850.19 EGB12698.1 - 3.7e-80 269.7 0.0 5e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_60s PF00428.19 EGB12698.1 - 0.071 13.7 1.9 0.12 12.9 1.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S13_N PF08069.12 EGB12700.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain U-box PF04564.15 EGB12701.1 - 2.8e-09 37.0 0.0 5.7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGB12701.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Mito_carr PF00153.27 EGB12702.1 - 1.4e-05 24.9 2.8 0.0053 16.6 0.2 3.4 2 1 0 3 3 3 3 Mitochondrial carrier protein Melibiase_2 PF16499.5 EGB12703.1 - 3.5e-57 193.7 1.9 6.3e-57 192.9 1.9 1.4 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGB12703.1 - 2.8e-19 69.0 0.3 5.7e-18 64.8 0.1 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGB12703.1 - 0.00012 21.2 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 EGB12703.1 - 0.004 17.4 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain zf_PR_Knuckle PF18445.1 EGB12703.1 - 0.18 11.6 0.1 23 4.9 0.0 2.3 2 0 0 2 2 2 0 PR zinc knuckle motif Dynein_light PF01221.18 EGB12704.1 - 1.3e-17 63.9 0.1 1.4e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TBCC PF07986.12 EGB12705.1 - 1.2e-20 73.5 0.1 1.3e-20 73.4 0.1 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor C PP2C PF00481.21 EGB12706.1 - 2.2e-28 99.6 0.0 2.5e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C MR_MLE_C PF13378.6 EGB12707.1 - 1.2e-35 123.1 2.4 1.5e-35 122.8 2.4 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGB12707.1 - 1.7e-12 47.6 0.2 2.7e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain YjbE PF11106.8 EGB12707.1 - 0.35 11.1 2.3 0.97 9.7 2.3 1.8 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE EF-1_beta_acid PF10587.9 EGB12708.1 - 0.013 15.9 0.8 0.013 15.9 0.8 9.3 7 2 2 9 9 9 0 Eukaryotic elongation factor 1 beta central acidic region APC_r PF05923.12 EGB12708.1 - 0.049 13.4 0.2 30 4.5 0.0 3.2 3 0 0 3 3 3 0 APC repeat Spb1_C PF07780.12 EGB12709.1 - 1.8e-53 181.4 19.4 1.8e-53 181.4 19.4 3.1 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EGB12709.1 - 9.3e-53 178.9 0.0 1.9e-52 177.9 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EGB12709.1 - 5.2e-37 127.2 1.2 5.2e-37 127.2 1.2 4.4 5 1 0 5 5 5 1 Domain of unknown function (DUF3381) AroM PF07302.11 EGB12709.1 - 0.021 14.2 0.0 0.021 14.2 0.0 2.5 3 0 0 3 3 3 0 AroM protein Methyltr_RsmB-F PF01189.17 EGB12709.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F TPR_11 PF13414.6 EGB12710.1 - 6.3e-39 131.4 17.3 5.2e-10 38.8 0.1 6.1 1 1 5 6 6 6 6 TPR repeat TPR_2 PF07719.17 EGB12710.1 - 6.5e-39 128.9 13.7 8.3e-07 28.7 0.0 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12710.1 - 1.7e-38 128.9 10.4 7.8e-07 28.7 0.0 6.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGB12710.1 - 5.2e-32 107.4 4.0 3.3e-05 23.8 0.0 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 EGB12710.1 - 3e-24 83.6 11.1 2.2e-05 24.5 0.3 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGB12710.1 - 1.3e-19 70.5 21.9 4.2e-09 36.9 1.4 4.6 2 1 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGB12710.1 - 4.3e-18 64.5 16.5 0.0023 18.6 0.1 6.1 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 EGB12710.1 - 1.3e-16 60.9 17.7 5.7e-05 23.5 0.6 4.7 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGB12710.1 - 1e-15 57.8 18.6 3.3e-06 27.3 0.4 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGB12710.1 - 2.2e-14 52.3 7.0 0.024 14.7 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGB12710.1 - 1e-13 51.2 13.3 2.4e-05 24.4 0.7 4.2 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGB12710.1 - 2.7e-13 49.6 4.1 0.52 11.1 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGB12710.1 - 2.3e-10 40.0 17.9 0.035 14.0 0.2 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.14 EGB12710.1 - 5.2e-06 26.6 5.4 5.4 7.9 0.0 5.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGB12710.1 - 3.2e-05 23.8 0.1 0.64 10.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TOM20_plant PF06552.12 EGB12710.1 - 9.9e-05 22.2 3.0 0.16 11.7 0.0 3.6 2 2 1 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 DUF4919 PF16266.5 EGB12710.1 - 0.00016 21.7 0.6 0.51 10.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4919) BTAD PF03704.17 EGB12710.1 - 0.00018 21.9 9.0 0.13 12.7 1.8 3.2 1 1 2 3 3 3 2 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 EGB12710.1 - 0.00031 20.7 7.4 0.018 15.0 1.2 2.3 2 1 0 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 EGB12710.1 - 0.00035 20.7 7.2 0.023 14.9 0.6 3.1 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 EGB12710.1 - 0.00077 18.5 3.6 0.11 11.4 0.8 2.2 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EGB12710.1 - 0.0012 18.1 7.8 0.14 11.3 1.4 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TraF PF13728.6 EGB12710.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein TPR_20 PF14561.6 EGB12710.1 - 0.15 12.4 12.1 0.87 10.0 0.1 3.9 1 1 2 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGB12710.1 - 0.15 11.8 8.6 0.99 9.1 1.5 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain Pkinase PF00069.25 EGB12711.1 - 1.1e-69 234.8 0.0 1.2e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12711.1 - 1.8e-39 135.6 0.0 2.4e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB12711.1 - 0.0011 18.4 0.0 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 EGB12711.1 - 0.008 16.9 0.4 0.016 15.9 0.4 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 EGB12711.1 - 0.01 15.8 1.4 0.022 14.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB12711.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Acetyltransf_1 PF00583.25 EGB12713.1 - 5.4e-14 52.4 0.0 1.1e-13 51.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGB12713.1 - 2e-09 37.3 0.0 3.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGB12713.1 - 8.9e-09 35.7 0.0 2.5e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGB12713.1 - 1e-07 31.9 0.0 9.1e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGB12713.1 - 0.001 18.8 0.0 0.0056 16.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGB12713.1 - 0.041 14.6 0.0 0.079 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGB12713.1 - 0.17 12.0 0.4 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EGB12713.1 - 0.22 11.6 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.27 EGB12714.1 - 1.6e-53 181.1 0.1 2.5e-53 180.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGB12714.1 - 1.5e-20 73.0 0.0 3.3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 EGB12714.1 - 7.6e-08 32.4 0.2 1.5e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EGB12714.1 - 4.5e-05 22.9 0.1 7.2e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU_D2 PF03144.25 EGB12714.1 - 0.0024 18.2 0.3 0.0068 16.8 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 EGB12714.1 - 0.0043 16.6 0.2 0.054 13.0 0.1 2.7 3 1 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.21 EGB12714.1 - 0.0077 15.7 0.0 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 EGB12714.1 - 0.01 15.3 0.0 0.036 13.5 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_II PF14492.6 EGB12714.1 - 0.042 13.9 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Elongation Factor G, domain II AIG1 PF04548.16 EGB12714.1 - 0.053 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family CPBP PF02517.16 EGB12715.1 - 8.6e-19 67.7 1.4 1.6e-18 66.9 1.4 1.4 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease DUF543 PF04418.12 EGB12715.1 - 0.21 11.6 5.9 0.45 10.5 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF543) EF-hand_7 PF13499.6 EGB12716.1 - 5.6e-18 65.2 0.5 4.1e-09 36.8 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB12716.1 - 6.7e-15 53.5 3.2 2.2e-05 23.7 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGB12716.1 - 7e-15 53.6 0.7 5.6e-05 22.7 0.0 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EGB12716.1 - 1.2e-11 43.5 0.2 0.0056 16.1 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB12716.1 - 2.8e-10 39.9 2.2 0.00011 22.0 0.1 4.5 3 1 1 4 4 4 2 EF-hand domain pair TerB PF05099.13 EGB12716.1 - 0.0002 21.3 0.8 0.00042 20.3 0.7 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TerB EF-hand_4 PF12763.7 EGB12716.1 - 0.1 12.6 0.1 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 EGB12717.1 - 1.6e-17 61.8 3.3 0.0006 19.5 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGB12717.1 - 2.5e-16 59.9 2.8 1.5e-08 35.0 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB12717.1 - 2.6e-16 57.9 6.2 9e-05 21.8 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGB12717.1 - 5.9e-10 38.9 6.8 1.5e-06 27.9 0.4 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGB12717.1 - 4.9e-08 32.1 5.2 0.048 13.2 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 EGB12717.1 - 0.04 14.2 0.9 0.64 10.4 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain p25-alpha PF05517.12 EGB12717.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 p25-alpha DNA_pol_B_thumb PF14791.6 EGB12718.1 - 5.1e-21 74.6 0.0 9e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb UAA PF08449.11 EGB12719.1 - 4.1e-44 151.0 14.6 5e-44 150.7 14.6 1.1 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 EGB12719.1 - 1.1e-05 24.6 1.9 1.1e-05 24.6 1.9 1.9 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EGB12719.1 - 7.3e-05 22.2 11.6 0.0056 16.1 2.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EGB12719.1 - 0.00024 21.3 25.7 0.00066 19.9 8.0 3.0 2 1 0 2 2 2 2 EamA-like transporter family EamA PF00892.20 EGB12720.1 - 2.4e-15 56.9 30.1 4.7e-10 39.8 14.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family adh_short_C2 PF13561.6 EGB12721.1 - 1.6e-46 158.8 0.0 2e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGB12721.1 - 2.2e-45 154.5 0.2 2.6e-45 154.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGB12721.1 - 1.8e-09 37.7 0.1 3.4e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB12721.1 - 0.00014 21.5 0.1 0.00025 20.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGB12721.1 - 0.02 14.1 0.1 0.26 10.4 0.1 2.1 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 EGB12721.1 - 0.034 13.6 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EGB12721.1 - 0.04 13.8 0.2 0.074 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGB12721.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EGB12721.1 - 0.17 12.0 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SAC3_GANP PF03399.16 EGB12722.1 - 5e-55 187.0 0.0 7.8e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family RRM_1 PF00076.22 EGB12722.1 - 5e-23 80.7 0.1 2.9e-14 52.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSN8_PSD8_EIF3K PF10075.9 EGB12722.1 - 1.3e-07 31.7 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RRM_7 PF16367.5 EGB12722.1 - 0.01 16.0 0.0 0.03 14.4 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif A2L_zn_ribbon PF08792.10 EGB12723.1 - 0.2 11.4 0.2 0.51 10.1 0.2 1.7 1 0 0 1 1 1 0 A2L zinc ribbon domain DnaJ PF00226.31 EGB12724.1 - 2e-12 47.1 0.0 1.3e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain Dzip-like_N PF13815.6 EGB12724.1 - 4.8e-10 39.4 0.0 8.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal PDZ_6 PF17820.1 EGB12724.1 - 0.00088 19.1 0.6 0.0026 17.6 0.6 1.8 1 0 0 1 1 1 1 PDZ domain zf-C2H2 PF00096.26 EGB12724.1 - 0.00099 19.4 1.0 0.0015 18.9 0.1 1.9 2 0 0 2 2 1 1 Zinc finger, C2H2 type PDZ PF00595.24 EGB12724.1 - 0.003 17.9 0.1 0.0073 16.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Ank_4 PF13637.6 EGB12724.1 - 0.0034 17.9 0.1 0.69 10.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF629 PF04780.12 EGB12724.1 - 0.026 13.1 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Ank_2 PF12796.7 EGB12724.1 - 0.034 14.7 0.9 0.28 11.8 0.1 2.7 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) zf-C2H2_4 PF13894.6 EGB12724.1 - 0.059 14.2 0.2 0.17 12.8 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Rad60-SLD PF11976.8 EGB12724.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ARS2 PF04959.13 EGB12724.1 - 0.21 11.9 0.0 0.41 11.0 0.0 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Kinesin PF00225.23 EGB12725.1 - 1.8e-71 240.8 0.0 2.3e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGB12725.1 - 6.8e-35 120.2 0.0 9.3e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding Glutaredoxin PF00462.24 EGB12726.1 - 7.2e-19 67.8 0.0 1.5e-18 66.8 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 EGB12726.1 - 0.0015 18.9 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 EGB12726.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 EGB12726.1 - 0.025 14.8 0.2 0.069 13.3 0.1 1.6 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 EGB12726.1 - 0.031 14.7 0.2 0.051 14.0 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 EGB12726.1 - 0.078 13.4 0.0 0.099 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TraF PF13728.6 EGB12726.1 - 0.08 12.8 0.1 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein EF-hand_7 PF13499.6 EGB12727.1 - 3.7e-09 36.9 0.0 1.2e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB12727.1 - 2.7e-06 26.5 0.0 0.13 11.9 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB12727.1 - 0.00049 19.8 0.0 0.31 11.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain Leucyl-specific PF14795.6 EGB12727.1 - 0.12 12.5 0.4 0.65 10.1 0.4 2.3 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain EF-hand_5 PF13202.6 EGB12727.1 - 0.13 11.8 0.1 12 5.5 0.1 2.6 2 0 0 2 2 2 0 EF hand zf-3CxxC PF13695.6 EGB12727.1 - 0.36 11.3 1.7 0.65 10.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding domain Glutaredoxin PF00462.24 EGB12728.1 - 1.4e-17 63.7 0.0 2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EGB12728.1 - 0.019 15.4 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ABC_tran PF00005.27 EGB12729.1 - 8.5e-19 68.4 0.9 6e-18 65.7 0.0 3.0 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGB12729.1 - 7e-07 29.4 1.1 0.016 15.1 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGB12729.1 - 1.4e-05 24.7 0.2 0.014 14.8 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGB12729.1 - 0.00012 22.2 0.6 0.023 14.9 0.3 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGB12729.1 - 0.00059 19.5 1.6 0.00065 19.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGB12729.1 - 0.001 18.7 0.1 0.68 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EGB12729.1 - 0.0029 18.1 0.1 0.0043 17.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGB12729.1 - 0.0089 16.3 0.4 0.55 10.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGB12729.1 - 0.01 16.2 7.6 0.042 14.2 0.8 3.2 2 2 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EGB12729.1 - 0.018 15.5 0.1 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGB12729.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 EGB12729.1 - 0.059 13.3 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 EGB12729.1 - 0.074 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGB12729.1 - 0.098 12.6 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 EGB12729.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.6 EGB12729.1 - 0.14 12.4 0.2 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PX PF00787.24 EGB12730.1 - 1.5e-09 37.8 0.0 3.9e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 PX domain DnaJ PF00226.31 EGB12730.1 - 0.16 12.1 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain DUF726 PF05277.12 EGB12731.1 - 2e-64 217.7 12.0 2.1e-26 92.7 0.5 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF726) FKBP_C PF00254.28 EGB12732.1 - 2.6e-18 66.1 0.0 2.8e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase adh_short PF00106.25 EGB12733.1 - 7.7e-36 123.4 0.9 1.1e-35 122.9 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB12733.1 - 2.4e-23 82.9 0.3 3.2e-23 82.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB12733.1 - 3e-07 30.5 1.3 1.4e-06 28.3 1.3 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB12733.1 - 1.1e-06 28.3 0.1 1.5e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGB12733.1 - 8.5e-06 25.0 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGB12733.1 - 0.0025 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGB12733.1 - 0.046 12.8 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PheRS_DBD3 PF18553.1 EGB12733.1 - 0.12 12.7 0.3 13 6.2 0.1 2.8 3 0 0 3 3 3 0 PheRS DNA binding domain 3 ThiF PF00899.21 EGB12733.1 - 0.17 11.2 0.6 0.34 10.2 0.6 1.4 1 0 0 1 1 1 0 ThiF family Melibiase_2 PF16499.5 EGB12734.1 - 9.5e-35 120.1 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGB12734.1 - 0.018 15.1 0.2 0.14 12.3 0.1 2.2 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain G-alpha PF00503.20 EGB12735.1 - 1.2e-56 192.4 0.0 1.7e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGB12735.1 - 4.5e-09 36.0 0.0 8.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Myosin_head PF00063.21 EGB12735.1 - 0.23 9.6 0.0 0.29 9.3 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) CactinC_cactus PF09732.9 EGB12736.1 - 2.7e-57 192.1 2.5 3e-57 192.0 2.5 1.0 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein APH PF01636.23 EGB12737.1 - 1.6e-09 38.0 11.6 1.6e-09 38.0 11.6 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGB12737.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EGB12737.1 - 0.3 10.6 0.0 0.45 10.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FAD_binding_4 PF01565.23 EGB12738.1 - 1.2e-23 83.4 3.8 1.9e-23 82.7 1.7 2.4 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGB12738.1 - 2.2e-08 34.0 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Chlorophyllase2 PF12740.7 EGB12738.1 - 0.00015 20.8 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGB12738.1 - 0.00071 18.9 0.0 0.032 13.5 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGB12738.1 - 0.0082 15.8 0.9 0.026 14.2 0.2 2.2 2 1 0 2 2 2 1 Putative esterase Glutaredoxin PF00462.24 EGB12739.1 - 3.2e-08 33.6 0.0 0.001 19.2 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin CHORD PF04968.12 EGB12739.1 - 1.1 10.0 4.7 0.42 11.4 0.7 2.1 2 0 0 2 2 2 0 CHORD Fea1 PF07692.11 EGB12740.1 - 1.5e-15 57.1 4.4 1.5e-15 57.1 4.4 3.0 3 1 0 3 3 3 1 Low iron-inducible periplasmic protein Glyco_hyd_65N_2 PF14498.6 EGB12740.1 - 2.4e-06 27.6 0.0 7e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.24 EGB12741.1 - 8.5e-17 61.2 16.7 1.4e-13 50.5 7.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGB12741.1 - 2e-12 46.7 41.0 7e-08 31.8 22.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGB12741.1 - 0.0023 16.4 3.8 0.0023 16.4 3.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sel1 PF08238.12 EGB12742.1 - 2.7e-15 56.5 63.2 0.00059 20.4 0.7 10.9 11 0 0 11 11 11 8 Sel1 repeat Laminin_G_3 PF13385.6 EGB12742.1 - 2e-12 47.5 0.0 4.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily LIM PF00412.22 EGB12743.1 - 5.4e-09 36.2 1.4 5.4e-09 36.2 1.4 2.1 2 0 0 2 2 2 1 LIM domain Glyco_hydro_20 PF00728.22 EGB12744.1 - 1.5e-40 139.7 0.0 2.4e-38 132.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Ion_trans PF00520.31 EGB12744.1 - 3.2e-21 75.7 4.4 4.5e-21 75.2 4.4 1.1 1 0 0 1 1 1 1 Ion transport protein DnaJ PF00226.31 EGB12744.1 - 1e-12 47.9 0.1 2e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain WW PF00397.26 EGB12744.1 - 3e-10 40.0 8.7 0.00015 21.8 0.4 2.6 2 0 0 2 2 2 2 WW domain Ion_trans_2 PF07885.16 EGB12744.1 - 1.1e-05 25.3 0.5 2.4e-05 24.2 0.5 1.5 1 0 0 1 1 1 1 Ion channel Glyco_hydro_20b PF02838.15 EGB12744.1 - 0.11 13.3 0.6 1.1 10.1 0.0 3.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 SAP PF02037.27 EGB12744.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 SAP domain Glycohydro_20b2 PF14845.6 EGB12744.1 - 0.14 12.8 0.0 0.57 10.8 0.0 2.1 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like Peptidase_S8 PF00082.22 EGB12745.1 - 8.6e-34 117.1 6.8 1.8e-33 116.1 6.8 1.6 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EGB12745.1 - 3.3e-11 43.1 0.1 5.5e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Wtap PF17098.5 EGB12746.1 - 0.021 14.8 1.7 0.056 13.4 1.7 1.7 1 0 0 1 1 1 0 WTAP/Mum2p family TSC22 PF01166.18 EGB12746.1 - 0.025 14.9 1.0 0.063 13.6 1.0 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family ABATE PF07336.11 EGB12746.1 - 1.9 9.2 14.6 3e+03 -1.2 14.6 3.0 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Cep57_CLD_2 PF14197.6 EGB12746.1 - 6.3 7.0 11.3 0.32 11.1 3.5 2.7 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 MGC-24 PF05283.11 EGB12747.1 - 7.4 7.0 14.6 2.4 8.6 6.9 2.3 1 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HMA PF00403.26 EGB12748.1 - 6.2e-05 23.4 0.1 0.00012 22.5 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Glyco_hydro_72 PF03198.14 EGB12749.1 - 0.075 12.3 0.0 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 Glucanosyltransferase MCM PF00493.23 EGB12750.1 - 1.2e-64 217.5 0.0 7.9e-59 198.5 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EGB12750.1 - 5.1e-22 78.1 0.3 8.6e-22 77.3 0.3 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGB12750.1 - 3.8e-14 52.9 0.4 7.2e-14 52.0 0.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGB12750.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGB12750.1 - 0.018 15.0 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM_N PF14551.6 EGB12750.1 - 0.031 14.9 0.0 0.066 13.8 0.0 1.4 1 0 0 1 1 1 0 MCM N-terminal domain AAA_3 PF07726.11 EGB12750.1 - 0.033 14.1 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 EGB12752.1 - 9.5e-36 122.8 0.0 1.4e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGB12752.1 - 1.8e-25 89.5 0.0 9.8e-25 87.1 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGB12752.1 - 5.7e-08 32.4 0.1 1.1e-05 25.0 0.1 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGB12752.1 - 0.00026 20.6 0.0 0.0054 16.3 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 EGB12752.1 - 0.0026 17.1 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGB12752.1 - 0.0048 17.0 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 EGB12752.1 - 0.0063 16.0 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 EGB12752.1 - 0.038 14.4 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 EGB12752.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 EGB12752.1 - 0.14 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 EGB12752.1 - 0.17 11.0 0.1 6.7 5.8 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit PITH PF06201.13 EGB12753.1 - 2.4e-23 83.0 0.0 3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain EF-hand_6 PF13405.6 EGB12754.1 - 1.1e-15 56.1 6.5 1.8e-05 24.3 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGB12754.1 - 1.2e-13 49.5 8.2 5e-05 22.6 0.3 3.5 3 1 1 4 4 4 3 EF hand EF-hand_5 PF13202.6 EGB12754.1 - 3e-11 42.3 2.5 0.0096 15.4 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGB12754.1 - 6.9e-09 36.0 5.0 0.0017 18.8 2.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB12754.1 - 0.0036 17.1 5.1 0.056 13.3 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 EGB12754.1 - 0.052 13.5 0.6 0.8 9.7 0.2 2.2 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 EGB12754.1 - 0.071 13.5 0.1 6.2 7.3 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain G-patch PF01585.23 EGB12756.1 - 0.0079 16.1 0.4 0.016 15.1 0.4 1.5 1 0 0 1 1 1 1 G-patch domain DUF3357 PF11837.8 EGB12756.1 - 0.13 12.7 0.4 0.43 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Ion_trans_2 PF07885.16 EGB12757.1 - 0.0043 17.0 4.5 0.0052 16.7 4.4 1.3 1 1 0 1 1 1 1 Ion channel DegT_DnrJ_EryC1 PF01041.17 EGB12758.1 - 7.1e-46 157.2 0.1 8.5e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGB12758.1 - 4.8e-10 39.2 0.1 1.1e-09 37.9 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Metallophos PF00149.28 EGB12759.1 - 1.5e-30 107.2 0.0 1.8e-30 107.0 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB12759.1 - 0.065 13.4 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 EGB12760.1 - 1.9e-22 79.6 0.1 6.7e-13 49.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB12760.1 - 2.9e-20 72.4 3.9 6.4e-09 36.2 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB12760.1 - 4.8e-14 52.3 2.8 3.7e-05 23.9 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12760.1 - 1.1e-11 43.8 0.1 0.036 14.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGB12760.1 - 2.5e-10 40.3 3.9 0.00011 22.5 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat GST_C_3 PF14497.6 EGB12761.1 - 5.4e-10 39.4 0.0 8.7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGB12761.1 - 0.00053 20.2 0.0 0.0012 19.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB12761.1 - 0.0014 18.6 3.4 0.0028 17.6 2.0 2.3 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Gelsolin PF00626.22 EGB12762.1 - 4.1e-20 71.5 0.0 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Gelsolin repeat Glyco_tranf_2_3 PF13641.6 EGB12763.1 - 8.6e-05 22.5 0.1 0.00078 19.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 C1_1 PF00130.22 EGB12763.1 - 0.048 13.5 0.3 0.12 12.3 0.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_9 PF15410.6 EGB12763.1 - 0.22 11.9 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain IQ PF00612.27 EGB12763.1 - 0.88 9.5 9.6 0.15 11.9 2.8 3.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif PHD PF00628.29 EGB12763.1 - 3.1 7.8 9.2 7 6.6 9.2 1.7 1 0 0 1 1 1 0 PHD-finger EF-hand_1 PF00036.32 EGB12764.1 - 4.3e-22 76.0 18.8 6.3e-07 28.5 2.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGB12764.1 - 1e-20 74.0 5.3 2.3e-13 50.4 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGB12764.1 - 3e-19 68.6 14.8 4.1e-13 49.0 0.9 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EGB12764.1 - 1.7e-18 64.9 13.1 1.1e-05 24.9 0.3 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGB12764.1 - 1.3e-13 49.8 19.1 1.1e-05 24.7 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 EGB12764.1 - 2.5e-07 30.6 2.6 0.0021 18.0 0.2 2.8 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB12764.1 - 0.021 15.1 0.0 2.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGB12764.1 - 0.25 11.2 2.8 4.2 7.3 0.1 3.0 3 0 0 3 3 3 0 EF hand Chloroa_b-bind PF00504.21 EGB12765.1 - 4.3e-33 115.1 0.0 5.3e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2970 PF11174.8 EGB12765.1 - 0.1 12.5 0.6 2.1 8.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) DSPc PF00782.20 EGB12766.1 - 1.3e-08 34.7 0.0 2.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF212 PF02681.14 EGB12766.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Divergent PAP2 family KOG2701 PF09762.9 EGB12767.1 - 0.012 15.8 2.1 0.019 15.2 2.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) CDC45 PF02724.14 EGB12767.1 - 1.8 6.7 10.0 2.3 6.4 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGB12767.1 - 9.4 4.9 6.6 12 4.5 6.6 1.1 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 EGB12768.1 - 2.9e-14 53.2 10.5 0.0022 18.8 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12768.1 - 9.5e-07 29.0 0.1 0.004 17.4 0.2 3.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EGB12768.1 - 0.0018 17.3 0.3 0.0018 17.3 0.3 1.7 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 EGB12768.1 - 7 7.3 14.9 7.6 7.2 0.1 4.6 3 1 1 4 4 4 0 PQQ-like domain Casc1_N PF15927.5 EGB12770.1 - 2.2e-16 60.1 25.9 2.2e-16 60.1 25.9 6.4 5 3 1 6 6 6 1 Cancer susceptibility candidate 1 N-terminus COMM_domain PF07258.14 EGB12770.1 - 0.00015 21.8 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 COMM domain Mito_carr PF00153.27 EGB12771.1 - 5.6e-56 186.5 5.0 4.1e-25 87.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 EGB12772.1 - 1e-11 44.5 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB12772.1 - 0.0059 16.7 0.0 0.0086 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EGB12772.1 - 0.088 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HECT PF00632.25 EGB12773.1 - 5.1e-40 137.9 0.0 5.7e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AMP-binding PF00501.28 EGB12774.1 - 4e-44 150.9 0.0 5.8e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_3 PF00202.21 EGB12774.1 - 5.2e-15 55.0 0.0 9.4e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III AMP-binding_C PF13193.6 EGB12774.1 - 4.8e-07 30.7 0.2 1.8e-06 28.8 0.2 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGB12774.1 - 1.4e-05 25.0 0.1 3.1e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Fer4_12 PF13353.6 EGB12774.1 - 0.00032 21.0 0.0 0.00067 19.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGB12774.1 - 0.0052 16.9 0.0 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain CMD PF02627.20 EGB12774.1 - 0.0064 16.5 1.8 0.0064 16.5 1.8 4.0 4 0 0 4 4 4 1 Carboxymuconolactone decarboxylase family Radical_SAM PF04055.21 EGB12774.1 - 0.075 13.4 0.0 0.57 10.5 0.0 2.6 2 1 0 2 2 2 0 Radical SAM superfamily Sugar_tr PF00083.24 EGB12775.1 - 1.9e-77 261.1 15.4 2.2e-77 260.9 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGB12775.1 - 8.2e-16 57.9 34.9 8.2e-16 57.9 34.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EGB12775.1 - 0.5 8.6 7.6 0.14 10.4 2.2 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1422 PF07226.11 EGB12775.1 - 9 6.3 7.5 0.4 10.7 0.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) COesterase PF00135.28 EGB12776.1 - 7.9e-50 170.2 0.9 9.1e-42 143.6 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGB12776.1 - 0.00044 20.2 0.2 0.0031 17.4 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGB12776.1 - 0.007 15.9 0.1 0.0095 15.4 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Cupin_2 PF07883.11 EGB12777.1 - 7.8e-25 86.4 0.2 1.9e-12 46.7 0.0 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGB12777.1 - 3.5e-15 55.4 0.1 2.7e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EGB12777.1 - 2.3e-06 27.5 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain AraC_binding_2 PF14525.6 EGB12777.1 - 0.0084 15.8 0.0 0.057 13.1 0.0 2.1 2 0 0 2 2 2 1 AraC-binding-like domain Cupin_6 PF12852.7 EGB12777.1 - 0.036 13.8 0.1 0.13 12.0 0.1 1.8 1 1 1 2 2 2 0 Cupin CENP-C_C PF11699.8 EGB12777.1 - 0.037 14.2 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Mif2/CENP-C like Mannitol_dh_C PF08125.13 EGB12778.1 - 9.8e-113 375.6 0.0 2.4e-55 187.7 0.0 2.2 2 0 0 2 2 2 2 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EGB12778.1 - 1.2e-60 204.1 0.0 6.7e-31 107.5 0.0 2.5 2 0 0 2 2 2 2 Mannitol dehydrogenase Rossmann domain zf-C3HC4_3 PF13920.6 EGB12778.1 - 8.8e-07 28.7 10.8 1.5e-06 27.9 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB12778.1 - 2.9e-05 24.3 12.4 5.2e-05 23.5 12.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGB12778.1 - 0.00017 21.4 12.0 0.00027 20.7 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGB12778.1 - 0.0018 18.1 11.6 0.0033 17.2 11.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB12778.1 - 0.017 15.1 13.0 0.03 14.3 13.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB12778.1 - 0.033 14.2 7.7 0.064 13.3 7.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EGB12778.1 - 0.14 12.0 5.6 0.4 10.5 5.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGB12778.1 - 0.19 11.6 11.9 0.35 10.8 11.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGB12778.1 - 0.84 9.8 10.0 1.5 9.0 10.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ank_2 PF12796.7 EGB12779.1 - 1.3e-16 60.9 0.2 2.5e-13 50.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB12779.1 - 1.4e-14 54.2 0.1 7.4e-09 36.0 0.2 3.5 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGB12779.1 - 1.6e-14 53.8 0.2 2.2e-07 31.0 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB12779.1 - 6.8e-11 42.1 0.6 0.00024 21.4 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGB12779.1 - 4.9e-09 35.7 0.2 0.00022 21.4 0.1 4.4 4 1 0 4 4 4 1 Ankyrin repeat Glyco_transf_8 PF01501.20 EGB12780.1 - 3.9e-09 36.4 0.0 0.00084 19.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGB12780.1 - 0.21 10.9 0.1 0.29 10.5 0.1 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 EGB12781.1 - 1.2e-08 34.8 0.0 0.002 17.8 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 Porin_1 PF00267.21 EGB12781.1 - 0.13 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Gram-negative porin Mannosyl_trans3 PF11051.8 EGB12781.1 - 0.28 10.5 0.1 0.39 10.0 0.1 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative DUF924 PF06041.11 EGB12782.1 - 3.6e-36 125.0 0.1 4.1e-36 124.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) HORMA PF02301.18 EGB12783.1 - 6.2e-05 22.7 0.0 6.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 HORMA domain DOT1 PF08123.13 EGB12784.1 - 1.7e-12 47.3 0.0 2.7e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EGB12784.1 - 0.033 14.9 0.5 0.11 13.2 0.5 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGB12784.1 - 0.045 13.6 0.2 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGB12784.1 - 0.054 13.3 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGB12784.1 - 0.06 14.0 0.1 0.18 12.5 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EGB12784.1 - 0.15 11.5 0.1 0.33 10.4 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase DCP1 PF06058.13 EGB12785.1 - 1.1e-26 93.0 0.0 1.2e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family ATP_bind_3 PF01171.20 EGB12786.1 - 0.0021 17.8 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Aldo_ket_red PF00248.21 EGB12787.1 - 1.8e-43 148.8 0.0 2.7e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Amino_oxidase PF01593.24 EGB12790.1 - 1.4e-48 166.3 0.0 1.6e-48 166.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB12790.1 - 1.8e-11 44.1 0.2 3.9e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB12790.1 - 2.9e-06 27.1 0.4 6.1e-06 26.0 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB12790.1 - 8.1e-05 21.9 0.2 0.0003 20.0 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGB12790.1 - 8.6e-05 22.1 0.1 0.00012 21.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGB12790.1 - 0.00053 20.5 0.2 0.001 19.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB12790.1 - 0.00081 18.7 0.1 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGB12790.1 - 0.0026 17.1 0.5 0.0037 16.6 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGB12790.1 - 0.0081 15.2 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 EGB12790.1 - 0.028 13.5 0.2 0.039 13.0 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A EF-hand_1 PF00036.32 EGB12791.1 - 3.1e-12 45.1 15.3 0.00016 21.0 0.2 5.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EGB12791.1 - 1.1e-11 43.6 5.9 6.4e-05 22.6 0.1 4.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 EGB12791.1 - 5.4e-11 42.8 5.3 2.4e-05 24.7 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB12791.1 - 0.00025 20.4 5.2 0.1 12.1 0.2 3.0 3 0 0 3 3 3 2 EF hand DUF4915 PF16261.5 EGB12791.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4915) Pox_Ag35 PF03286.14 EGB12791.1 - 0.11 12.3 3.6 4.3 7.1 0.5 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein EF-hand_8 PF13833.6 EGB12791.1 - 4.8 7.1 12.2 16 5.5 0.2 4.3 4 2 0 4 4 4 0 EF-hand domain pair Bestrophin PF01062.21 EGB12792.1 - 1.1e-62 212.1 5.7 1.4e-62 211.8 5.7 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel F-box PF00646.33 EGB12792.1 - 3 7.8 4.9 0.57 10.1 0.8 2.0 2 0 0 2 2 2 0 F-box domain PhyH PF05721.13 EGB12793.1 - 6e-05 23.4 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TFIIB_C_1 PF18542.1 EGB12793.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 F_actin_bund_C PF18060.1 EGB12794.1 - 6e-26 90.4 22.4 6e-26 90.4 22.4 1.7 1 1 0 1 1 1 1 F actin bundling C terminal EF-hand_5 PF13202.6 EGB12794.1 - 0.077 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 EF hand adh_short PF00106.25 EGB12795.1 - 6.8e-34 117.0 0.6 1e-25 90.3 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGB12795.1 - 1.5e-27 96.7 2.1 2.5e-18 66.5 0.4 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB12795.1 - 2e-06 27.8 0.3 2.8e-06 27.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB12795.1 - 2.2e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB12795.1 - 0.0037 17.2 0.8 0.0059 16.5 0.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGB12795.1 - 0.0037 16.7 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGB12795.1 - 0.03 14.6 0.3 0.059 13.6 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EGB12795.1 - 0.11 11.6 0.0 0.81 8.8 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein PI3_PI4_kinase PF00454.27 EGB12796.1 - 1e-31 110.7 0.0 2.4e-23 83.2 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase MAPEG PF01124.18 EGB12796.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 MAPEG family Sec23_trunk PF04811.15 EGB12798.1 - 4.9e-63 212.9 0.0 6.7e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGB12798.1 - 3.9e-26 91.6 0.0 7e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGB12798.1 - 7.1e-24 83.6 0.1 1.8e-23 82.3 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGB12798.1 - 1.5e-16 60.1 6.2 2.9e-16 59.2 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGB12798.1 - 3.4e-09 36.5 0.0 6.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 EGB12798.1 - 0.014 16.0 0.0 2.9 8.6 0.0 2.5 2 0 0 2 2 2 0 von Willebrand factor type A domain DNA_ligase_IV PF11411.8 EGB12798.1 - 0.077 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 DNA ligase IV FAD_binding_3 PF01494.19 EGB12800.1 - 7.9e-12 45.1 0.1 8.7e-12 44.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain EGF_2 PF07974.13 EGB12801.1 - 3.8e-18 65.5 52.0 3.1e-09 37.0 2.4 5.3 5 0 0 5 5 5 4 EGF-like domain Laminin_EGF PF00053.24 EGB12801.1 - 1.7 8.8 39.9 0.084 13.0 7.4 4.2 3 2 1 4 4 4 0 Laminin EGF domain EGF PF00008.27 EGB12801.1 - 5 7.5 48.7 0.27 11.6 2.5 5.2 6 0 0 6 6 6 0 EGF-like domain RIB43A PF05914.12 EGB12802.1 - 1.3e-47 162.4 26.4 1.6e-47 162.0 26.4 1.1 1 0 0 1 1 1 1 RIB43A AMP-binding PF00501.28 EGB12803.1 - 4e-29 101.5 6.2 4.5e-18 65.1 0.0 3.7 1 1 2 3 3 3 3 AMP-binding enzyme PQQ_2 PF13360.6 EGB12803.1 - 1.5e-19 70.5 11.7 1.2e-14 54.4 7.7 2.6 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 EGB12803.1 - 9.6e-16 57.7 45.7 7.6e-05 23.1 5.8 7.5 6 1 1 7 7 7 4 PQQ-like domain HTH_9 PF08221.11 EGB12803.1 - 1.3e-06 28.4 0.0 0.00075 19.5 0.0 3.3 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain PQQ PF01011.21 EGB12803.1 - 7.2e-05 22.5 7.2 0.00059 19.6 0.2 4.4 4 0 0 4 4 4 1 PQQ enzyme repeat PP-binding PF00550.25 EGB12803.1 - 0.003 17.9 0.0 0.0073 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site TFIIE_alpha PF02002.17 EGB12803.1 - 0.14 12.0 0.0 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 TFIIE alpha subunit DUF3357 PF11837.8 EGB12803.1 - 1.7 9.1 5.8 1.2 9.7 1.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Guanylate_cyc PF00211.20 EGB12806.1 - 1.1e-19 70.8 0.0 8.9e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 EGB12806.1 - 2.9e-11 44.0 0.2 2.9e-11 44.0 0.2 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EGB12806.1 - 0.002 18.4 0.0 0.027 14.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain Med2 PF11214.8 EGB12807.1 - 0.0011 19.1 6.2 0.0011 19.1 6.2 3.7 2 2 2 4 4 4 1 Mediator complex subunit 2 DUF3541 PF12060.8 EGB12807.1 - 0.012 15.3 0.6 0.012 15.3 0.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3541) TRAF_BIRC3_bd PF16673.5 EGB12807.1 - 0.019 14.8 0.2 0.019 14.8 0.2 4.8 6 0 0 6 6 6 0 TNF receptor-associated factor BIRC3 binding domain Tropomyosin_1 PF12718.7 EGB12807.1 - 0.087 13.0 36.6 0.065 13.4 4.0 3.9 2 1 0 3 3 3 0 Tropomyosin like Img2 PF05046.14 EGB12807.1 - 0.28 11.5 2.8 6 7.2 2.8 3.2 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) TOPRIM_C PF16898.5 EGB12807.1 - 2.5 8.4 7.4 0.54 10.5 0.4 2.8 2 1 0 2 2 2 0 C-terminal associated domain of TOPRIM Nif11 PF07862.11 EGB12807.1 - 6.8 7.1 7.2 19 5.6 0.1 3.4 3 0 0 3 3 3 0 Nif11 domain UPF0449 PF15136.6 EGB12807.1 - 9.8 6.7 12.7 4 8.0 4.0 3.7 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 Dus PF01207.17 EGB12808.1 - 2.6e-20 72.7 0.1 1e-19 70.8 0.1 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Ank_2 PF12796.7 EGB12809.1 - 5.8e-20 71.7 5.1 3.6e-09 37.1 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB12809.1 - 1.9e-19 69.5 4.1 9.9e-08 32.1 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB12809.1 - 3.7e-16 59.3 2.1 6.8e-08 32.9 0.1 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12809.1 - 5.1e-15 54.1 0.8 0.0023 18.3 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EGB12809.1 - 7.9e-14 51.4 3.2 0.00083 19.7 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Rieske PF00355.26 EGB12810.1 - 1.4e-11 44.2 0.0 2.5e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EGB12810.1 - 7e-08 32.8 0.4 1.4e-07 31.9 0.4 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Myb_DNA-binding PF00249.31 EGB12811.1 - 7.4e-14 51.7 0.1 8.7e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGB12811.1 - 0.018 15.3 0.0 0.022 15.0 0.0 1.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain Ran_BP1 PF00638.18 EGB12812.1 - 2.2e-05 24.7 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Ank_2 PF12796.7 EGB12813.1 - 5.1e-15 55.8 0.1 1.1e-10 41.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB12813.1 - 7.3e-15 54.8 1.7 8.9e-08 32.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12813.1 - 1.4e-14 52.7 0.4 0.00031 21.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGB12813.1 - 2.2e-13 50.4 1.4 6.4e-06 26.6 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB12813.1 - 8.3e-08 32.3 1.4 0.14 12.7 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeat DUF2773 PF10971.8 EGB12813.1 - 0.06 13.5 0.0 10 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) Ion_trans_2 PF07885.16 EGB12814.1 - 1.8e-11 43.8 6.0 2e-11 43.7 6.0 1.0 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB12814.1 - 0.00023 20.5 2.8 0.00024 20.4 2.8 1.0 1 0 0 1 1 1 1 Ion transport protein RAB3GAP2_N PF14655.6 EGB12815.1 - 4.5e-25 88.8 0.0 6.3e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ank_2 PF12796.7 EGB12815.1 - 8.2e-23 80.8 0.0 2e-05 25.1 0.0 5.6 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB12815.1 - 2.8e-18 66.0 5.2 9.4e-06 26.1 0.3 6.2 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12815.1 - 1.9e-13 49.3 1.8 0.65 10.7 0.0 9.3 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 EGB12815.1 - 4.2e-12 46.0 13.3 9.4e-06 25.8 0.3 6.7 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EGB12815.1 - 5.9e-11 42.3 6.0 0.0011 19.3 0.2 7.2 7 0 0 7 7 7 3 Ankyrin repeat O-FucT PF10250.9 EGB12816.1 - 4.9e-37 128.4 0.0 6.3e-14 52.4 0.0 5.2 3 1 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase Arylsulfotrans PF05935.11 EGB12816.1 - 4.5e-10 39.0 0.0 9.2e-09 34.7 0.0 2.0 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) U-box PF04564.15 EGB12816.1 - 0.00052 20.1 0.0 0.00095 19.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain Arylsulfotran_2 PF14269.6 EGB12816.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) 3Beta_HSD PF01073.19 EGB12817.1 - 5.2e-37 127.4 0.0 6.9e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGB12817.1 - 4.8e-27 95.0 0.0 6.7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGB12817.1 - 5.7e-14 52.4 0.0 7.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGB12817.1 - 2e-12 46.9 0.0 4.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EGB12817.1 - 8.2e-12 45.2 0.0 4.4e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGB12817.1 - 1.5e-07 30.8 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGB12817.1 - 2.1e-07 30.3 0.0 4.1e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EGB12817.1 - 0.00019 21.4 0.3 0.00083 19.3 0.3 2.0 2 1 0 2 2 2 1 KR domain NmrA PF05368.13 EGB12817.1 - 0.0046 16.6 0.0 0.031 13.8 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGB12817.1 - 0.006 16.1 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EGB12817.1 - 0.074 13.3 0.0 0.27 11.5 0.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Kelch_5 PF13854.6 EGB12818.1 - 3.1e-06 27.0 0.2 0.00021 21.2 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 EGB12818.1 - 7e-06 26.0 0.3 0.0048 16.9 0.1 3.2 2 0 0 2 2 2 2 Galactose oxidase, central domain NAD_binding_9 PF13454.6 EGB12818.1 - 0.0052 16.8 3.3 0.55 10.2 0.4 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Kelch_3 PF13415.6 EGB12818.1 - 0.0072 16.6 4.9 0.45 10.9 0.0 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain ThiF PF00899.21 EGB12818.1 - 0.087 12.2 0.3 0.18 11.1 0.3 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 EGB12818.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 EGB12818.1 - 0.16 11.2 0.0 0.72 9.0 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGB12818.1 - 0.19 12.0 1.6 0.62 10.3 1.6 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain His_Phos_1 PF00300.22 EGB12819.1 - 5.3e-34 117.6 1.5 2.2e-23 83.0 0.6 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) TAF6_C PF07571.13 EGB12819.1 - 0.042 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain tRNA-synt_2d PF01409.20 EGB12820.1 - 1.2e-83 280.4 0.0 1.6e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGB12820.1 - 3.6e-14 52.8 0.2 9.4e-14 51.4 0.2 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 EGB12820.1 - 8e-12 44.7 0.1 1.5e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 EGB12820.1 - 8.4e-05 22.1 0.0 0.028 13.8 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EGB12820.1 - 0.0019 17.4 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) MarR_2 PF12802.7 EGB12820.1 - 0.0059 16.5 0.0 0.075 12.9 0.0 2.3 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 EGB12820.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Cys_Met_Meta_PP PF01053.20 EGB12821.1 - 3.4e-132 440.6 0.0 3.9e-132 440.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGB12821.1 - 1e-08 34.5 0.2 3.2e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGB12821.1 - 4.4e-07 29.5 0.3 1.4e-06 27.9 0.1 1.9 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGB12821.1 - 5.7e-05 22.4 0.0 9.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 EGB12821.1 - 0.00019 20.4 0.1 0.00049 19.1 0.0 1.7 2 0 0 2 2 2 1 Glycine cleavage system P-protein VP4_haemagglut PF00426.18 EGB12821.1 - 0.023 14.9 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain YHYH PF14240.6 EGB12822.1 - 1.5e-17 64.2 0.0 5.1e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 YHYH protein TIR_2 PF13676.6 EGB12823.1 - 1.5e-07 32.1 0.0 3.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 EGB12823.1 - 3.1e-06 27.1 0.0 4.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 TIR domain Atx10homo_assoc PF09759.9 EGB12823.1 - 0.00054 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Tyr-DNA_phospho PF06087.12 EGB12823.1 - 0.31 9.9 0.0 0.45 9.4 0.0 1.1 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase PFK PF00365.20 EGB12824.1 - 8.3e-57 192.7 0.0 1.1e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 EGB12824.1 - 6e-06 25.9 0.1 6e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EGB12824.1 - 0.00025 20.3 0.1 0.00036 19.8 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase NUDIX PF00293.28 EGB12825.1 - 4.6e-12 46.1 0.1 1.3e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain CysG_dimeriser PF10414.9 EGB12825.1 - 0.0011 18.6 3.4 0.22 11.3 0.2 2.4 2 0 0 2 2 2 2 Sirohaem synthase dimerisation region Inositol_P PF00459.25 EGB12826.1 - 1.1e-41 143.2 0.0 1.3e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 EGB12826.1 - 0.00036 20.1 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NUDIX PF00293.28 EGB12827.1 - 6.6e-17 61.8 0.0 9.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EGB12827.1 - 1.4e-05 24.7 6.7 2.3e-05 23.9 6.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF1451 PF07295.11 EGB12827.1 - 0.0041 17.2 1.5 0.0082 16.2 1.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon containing domain NUDIX-like PF09296.11 EGB12827.1 - 0.032 14.9 0.9 0.083 13.6 0.9 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain DUF35_N PF12172.8 EGB12827.1 - 0.31 10.9 5.6 0.41 10.6 1.4 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Phosducin PF02114.16 EGB12830.1 - 8.5e-21 74.1 0.0 3.2e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EGB12830.1 - 0.00036 20.5 0.0 0.0024 17.8 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Cwf_Cwc_15 PF04889.12 EGB12830.1 - 0.26 11.0 5.9 0.16 11.7 0.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Dynamin_N PF00350.23 EGB12832.1 - 6.3e-20 71.9 0.0 1e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 Dynamin family zf-C3HC4_2 PF13923.6 EGB12832.1 - 2.3e-08 33.8 10.0 4.9e-08 32.7 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB12832.1 - 3.9e-07 29.8 8.4 7.6e-07 28.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGB12832.1 - 6.6e-07 29.3 7.8 9.3e-07 28.8 6.4 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGB12832.1 - 1.3e-06 28.4 9.5 2.8e-06 27.4 9.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGB12832.1 - 1.5e-06 27.9 7.2 3.1e-06 27.0 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB12832.1 - 2.7e-06 27.6 8.6 5.5e-06 26.6 8.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EGB12832.1 - 8.9e-05 22.2 3.7 0.0002 21.1 3.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGB12832.1 - 0.00018 21.4 8.3 0.00037 20.4 8.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain MMR_HSR1 PF01926.23 EGB12832.1 - 0.00027 21.0 0.0 0.001 19.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-RING_6 PF14835.6 EGB12832.1 - 0.0006 19.6 3.3 0.0014 18.5 3.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EGB12832.1 - 0.0028 17.8 5.9 0.0054 16.8 5.9 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 AAA_16 PF13191.6 EGB12832.1 - 0.011 16.2 0.9 0.047 14.1 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain Prok-RING_4 PF14447.6 EGB12832.1 - 0.012 15.5 8.9 0.026 14.4 8.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AAA_28 PF13521.6 EGB12832.1 - 0.097 12.9 0.0 0.34 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGB12832.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system zf-rbx1 PF12678.7 EGB12832.1 - 0.15 12.4 4.4 0.4 11.0 4.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain RHD3 PF05879.12 EGB12832.1 - 0.3 9.2 0.0 0.43 8.7 0.0 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) zf-RING_11 PF17123.5 EGB12832.1 - 7.3 6.4 5.6 16 5.3 5.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Peptidase_S9 PF00326.21 EGB12833.1 - 6.2e-06 25.8 0.0 3.6e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGB12833.1 - 2.4e-05 23.7 0.1 0.026 13.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB12833.1 - 0.00013 21.7 0.1 0.09 12.4 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 EGB12833.1 - 0.0032 17.2 0.0 0.0032 17.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EGB12833.1 - 0.0034 18.0 2.8 0.28 11.8 1.3 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 EGB12833.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 EGB12833.1 - 0.056 13.4 0.0 1.4 8.8 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EGB12833.1 - 0.1 12.4 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 EGB12834.1 - 1.3e-100 337.8 0.2 1.5e-100 337.6 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase NUDIX PF00293.28 EGB12835.1 - 4.2e-11 43.0 0.2 4.8e-11 42.8 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.7 EGB12836.1 - 4.8e-10 39.9 0.0 1.9e-05 25.2 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGB12836.1 - 5.1e-08 33.3 0.2 7.2e-05 23.3 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB12836.1 - 6.1e-07 29.3 0.4 3.4 8.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGB12836.1 - 0.00023 21.4 0.2 0.47 10.8 0.0 2.9 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EGB12836.1 - 0.0026 18.1 0.3 32 5.2 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Sulfotransfer_2 PF03567.14 EGB12837.1 - 0.00042 20.3 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase family Glyco_hydro_43 PF04616.14 EGB12838.1 - 2.7e-11 43.3 0.4 4.5e-11 42.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Beta_helix PF13229.6 EGB12838.1 - 7.1e-05 22.7 1.3 0.0046 16.8 0.0 2.9 3 1 0 3 3 3 1 Right handed beta helix region Ephrin_rec_like PF07699.13 EGB12838.1 - 0.013 15.2 6.3 0.015 15.0 0.7 2.8 2 0 0 2 2 2 0 Putative ephrin-receptor like GYF_2 PF14237.6 EGB12839.1 - 1.7e-20 72.6 11.4 3.7e-06 26.7 0.4 4.1 4 0 0 4 4 4 3 GYF domain 2 SAM_2 PF07647.17 EGB12839.1 - 0.0087 16.1 0.0 0.032 14.3 0.0 1.9 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGB12839.1 - 0.13 12.7 0.2 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF3545 PF12065.8 EGB12839.1 - 1.1 9.3 5.9 18 5.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) End3 PF12761.7 EGB12839.1 - 7.9 6.6 9.7 7.4 6.7 1.2 2.5 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Pkinase PF00069.25 EGB12840.1 - 4.3e-46 157.4 0.0 5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12840.1 - 1.1e-31 110.1 0.0 1.3e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGB12840.1 - 0.00012 21.0 0.0 0.00037 19.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGB12840.1 - 0.0073 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGB12840.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EGB12840.1 - 0.17 11.5 0.0 6.1 6.4 0.0 2.4 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Sulfatase PF00884.23 EGB12841.1 - 1.1e-60 205.6 0.1 1.6e-60 205.1 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGB12841.1 - 5.2e-05 23.0 0.3 0.00036 20.2 0.1 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EGB12841.1 - 0.00033 21.4 0.0 0.00061 20.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Cation_efflux PF01545.21 EGB12842.1 - 2.8e-40 138.2 7.5 4.3e-40 137.6 7.5 1.3 1 0 0 1 1 1 1 Cation efflux family Ank_3 PF13606.6 EGB12843.1 - 0.011 16.2 1.9 2.5 8.9 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat Ank PF00023.30 EGB12843.1 - 0.054 14.0 0.7 3.2 8.4 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 EGB12843.1 - 0.061 13.9 2.1 21 5.8 0.0 4.3 4 1 0 4 4 4 0 Ankyrin repeats (many copies) DUF3397 PF11877.8 EGB12844.1 - 0.12 12.6 0.2 0.12 12.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) DUF373 PF04123.13 EGB12844.1 - 0.13 11.7 3.1 0.19 11.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Beta-lactamase PF00144.24 EGB12845.1 - 2.5e-19 69.7 0.3 2.5e-19 69.7 0.3 2.0 2 0 0 2 2 2 2 Beta-lactamase Asp_Arg_Hydrox PF05118.15 EGB12846.1 - 1.7e-40 138.5 0.1 1.8e-40 138.3 0.1 1.0 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 EGB12846.1 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.4 1 1 0 1 1 1 1 Cupin domain cobW PF02492.19 EGB12847.1 - 5.3e-57 192.2 2.0 6.8e-57 191.9 2.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB12847.1 - 9.7e-21 73.5 0.0 2.6e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 EGB12847.1 - 0.00039 20.0 0.9 0.29 10.7 0.1 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGB12847.1 - 0.00067 19.6 0.1 0.32 10.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EGB12847.1 - 0.012 15.8 0.3 0.057 13.7 0.3 2.1 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGB12847.1 - 0.02 14.0 0.1 0.043 12.9 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EGB12847.1 - 0.02 15.3 0.5 0.047 14.1 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EGB12847.1 - 0.05 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGB12847.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EGB12847.1 - 0.065 13.1 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.9 EGB12847.1 - 0.079 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TsaE PF02367.17 EGB12847.1 - 0.08 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGB12847.1 - 0.081 12.6 0.2 0.54 9.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGB12847.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGB12847.1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EGB12847.1 - 0.1 12.5 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGB12847.1 - 0.12 12.8 0.3 0.23 12.0 0.2 1.5 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 EGB12847.1 - 0.15 12.1 0.9 1.5 8.9 0.9 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase IMPDH PF00478.25 EGB12848.1 - 1.1e-80 271.2 3.9 2.4e-80 270.2 3.9 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGB12848.1 - 0.0006 18.9 3.7 0.00093 18.3 3.7 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase UAA PF08449.11 EGB12849.1 - 4.2e-44 151.0 5.1 5.5e-44 150.6 5.1 1.1 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 EGB12849.1 - 0.00031 19.8 0.8 0.00044 19.3 0.8 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EGB12849.1 - 1.3 9.1 9.6 0.16 12.1 1.6 2.4 2 0 0 2 2 2 0 EamA-like transporter family Ribosomal_L3 PF00297.22 EGB12851.1 - 1.6e-20 73.4 7.6 1.7e-18 66.8 5.1 2.5 2 1 1 3 3 3 2 Ribosomal protein L3 RPN6_N PF18055.1 EGB12852.1 - 2e-20 73.3 0.0 2.9e-19 69.5 0.0 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGB12852.1 - 3.2e-14 53.3 0.0 1.4e-13 51.3 0.0 2.1 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EGB12852.1 - 0.0001 21.9 0.3 0.00031 20.4 0.0 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 EGB12852.1 - 0.068 12.5 9.0 0.046 13.1 2.3 2.1 2 0 0 2 2 2 0 MalT-like TPR region TPR_12 PF13424.6 EGB12852.1 - 0.3 11.4 16.0 0.32 11.3 2.7 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RIBIOP_C PF04950.12 EGB12853.1 - 6.1e-80 268.8 0.0 7.2e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Sulfotransfer_2 PF03567.14 EGB12854.1 - 0.19 11.6 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family F_bP_aldolase PF01116.20 EGB12855.1 - 4.9e-80 269.0 0.0 5.9e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PRORP PF16953.5 EGB12856.1 - 7.6e-33 114.0 0.0 1.4e-32 113.2 0.0 1.3 1 1 0 1 1 1 1 Protein-only RNase P PPR_long PF17177.4 EGB12856.1 - 1.8e-24 86.3 1.4 2.5e-18 66.2 0.2 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 EGB12856.1 - 1.3e-05 25.3 0.1 0.013 15.7 0.0 3.1 1 1 2 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EGB12856.1 - 2.7e-05 24.2 0.0 0.0026 17.8 0.0 2.5 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 EGB12856.1 - 0.0038 17.4 0.3 1.8 9.0 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.7 EGB12856.1 - 0.035 13.8 1.6 5.7 6.7 0.0 3.7 3 0 0 3 3 3 0 PPR repeat DOT1 PF08123.13 EGB12857.1 - 3.8e-08 33.1 0.0 1.1e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 EGB12857.1 - 0.13 12.9 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain V-ATPase_H_C PF11698.8 EGB12858.1 - 1e-39 135.3 0.0 1.1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.23 EGB12858.1 - 2.2e-05 24.4 0.1 0.031 14.3 0.0 2.2 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB12858.1 - 0.0018 18.6 0.0 0.005 17.2 0.0 1.7 1 1 1 2 2 2 2 HEAT repeats DRIM PF07539.12 EGB12858.1 - 0.0033 15.8 0.0 0.0048 15.3 0.0 1.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.22 EGB12858.1 - 0.013 15.7 0.0 11 6.6 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat Arm_2 PF04826.13 EGB12858.1 - 0.021 14.3 0.0 0.025 14.1 0.0 1.0 1 0 0 1 1 1 0 Armadillo-like Cyt-b5 PF00173.28 EGB12858.1 - 0.021 14.9 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Arm_3 PF16186.5 EGB12858.1 - 0.041 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 Atypical Arm repeat Aldedh PF00171.22 EGB12859.1 - 1.8e-138 462.0 0.2 1.9e-97 326.7 0.2 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 EGB12859.1 - 0.2 10.6 5.6 0.19 10.7 2.0 2.2 2 1 0 2 2 2 0 Acyl-CoA reductase (LuxC) HGTP_anticodon PF03129.20 EGB12860.1 - 6.2e-11 42.3 0.2 4.1e-10 39.7 0.2 2.3 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGB12860.1 - 2e-06 27.9 0.0 3.7e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Cation_ATPase_C PF00689.21 EGB12861.1 - 5.8e-36 123.9 4.0 5.8e-36 123.9 4.0 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGB12861.1 - 4.2e-28 98.1 14.0 1.9e-22 79.6 2.4 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 EGB12861.1 - 9.2e-16 57.7 0.0 2.2e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGB12861.1 - 4.3e-11 43.5 5.0 3.9e-07 30.6 1.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGB12861.1 - 4e-08 32.8 0.0 7.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGB12861.1 - 0.0019 18.0 1.5 0.01 15.6 1.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 EGB12861.1 - 6 7.2 12.0 1.3 9.3 2.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Ephrin_rec_like PF07699.13 EGB12862.1 - 4.8e-30 103.1 88.6 4.4e-07 29.6 5.1 9.7 1 1 8 9 9 9 8 Putative ephrin-receptor like WW PF00397.26 EGB12862.1 - 3.3e-17 62.3 4.2 5.9e-08 32.7 1.1 2.7 2 0 0 2 2 2 2 WW domain Cupin_4 PF08007.12 EGB12862.1 - 8.1e-08 32.1 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein CarboxypepD_reg PF13620.6 EGB12862.1 - 0.25 11.6 10.9 2.5 8.5 0.7 4.2 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain MORN PF02493.20 EGB12864.1 - 2.2e-35 118.4 39.6 1.7e-06 27.6 2.6 6.0 6 0 0 6 6 6 6 MORN repeat HA2 PF04408.23 EGB12865.1 - 2.2e-25 89.0 0.0 5.3e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGB12865.1 - 3.5e-23 81.8 0.0 6.9e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGB12865.1 - 4.8e-12 46.2 0.0 1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EGB12865.1 - 6.8e-09 35.9 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 EGB12865.1 - 2.9e-05 24.4 0.0 6.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGB12865.1 - 0.00014 22.2 0.1 0.00034 21.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGB12865.1 - 0.00019 20.6 0.1 0.00038 19.6 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 EGB12865.1 - 0.00072 19.4 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGB12865.1 - 0.00097 18.9 4.3 0.0018 18.0 0.3 2.5 2 0 0 2 2 2 1 AAA domain Microtub_bd PF16796.5 EGB12865.1 - 0.017 15.0 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding Sigma54_activ_2 PF14532.6 EGB12865.1 - 0.026 14.6 0.0 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 EGB12865.1 - 0.081 12.5 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGB12865.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EGB12865.1 - 0.11 12.1 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGB12865.1 - 0.15 12.5 0.7 0.37 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Kinesin PF00225.23 EGB12865.1 - 0.26 10.2 0.0 0.41 9.5 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain FA_desaturase PF00487.24 EGB12866.1 - 2.1e-28 99.9 26.3 2.1e-28 99.9 26.3 1.4 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGB12866.1 - 1.8e-08 34.4 0.1 3.4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EGF_2 PF07974.13 EGB12867.1 - 4e-11 43.1 115.7 0.00044 20.5 4.3 11.0 12 1 1 13 13 13 7 EGF-like domain DinB_2 PF12867.7 EGB12868.1 - 0.0068 16.9 0.7 0.027 15.0 0.2 2.0 1 1 1 2 2 2 1 DinB superfamily Mobilization_B PF17511.2 EGB12868.1 - 0.012 16.0 0.8 0.012 16.0 0.8 1.4 1 1 0 1 1 1 0 Mobilization protein B HrpB2 PF09487.10 EGB12868.1 - 0.035 14.5 0.3 0.12 12.8 0.2 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Spidroin_MaSp PF11260.8 EGB12868.1 - 0.054 13.8 0.4 0.097 13.0 0.4 1.4 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 DUF2959 PF11172.8 EGB12868.1 - 0.095 12.8 0.7 0.21 11.7 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) DUF4164 PF13747.6 EGB12868.1 - 0.13 12.5 3.5 0.14 12.5 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) PRIMA1 PF16101.5 EGB12868.1 - 1.1 9.4 3.7 1.8 8.7 3.7 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EGB12868.1 - 1.2 8.6 9.7 1.7 8.0 5.7 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sulfotransfer_3 PF13469.6 EGB12869.1 - 0.17 12.3 2.4 2.3 8.5 0.0 2.7 2 1 1 3 3 3 0 Sulfotransferase family zinc_ribbon_4 PF13717.6 EGB12869.1 - 0.39 10.7 4.9 0.18 11.7 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain CNOT1_HEAT_N PF16419.5 EGB12870.1 - 0.00011 21.9 0.1 0.46 10.1 0.0 2.2 1 1 1 2 2 2 2 CCR4-NOT transcription complex subunit 1 HEAT repeat AAA PF00004.29 EGB12871.1 - 1.5e-33 116.0 0.0 2.1e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGB12871.1 - 3.7e-10 39.5 2.2 3.9e-10 39.4 0.6 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EGB12871.1 - 0.00013 22.3 0.1 0.00055 20.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EGB12871.1 - 0.00032 20.0 0.0 0.00043 19.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EGB12871.1 - 0.0049 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGB12871.1 - 0.024 14.6 0.0 0.18 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGB12871.1 - 0.028 13.8 0.1 0.58 9.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGB12871.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) XPG_N PF00752.17 EGB12872.1 - 1.7e-30 105.4 0.0 3.1e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGB12872.1 - 1.3e-29 102.4 0.1 2.6e-29 101.4 0.1 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EGB12872.1 - 7.5e-06 26.5 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EGB12872.1 - 0.002 18.7 0.1 0.0067 17.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EGB12872.1 - 0.0052 16.9 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif 5_3_exonuc_N PF02739.16 EGB12872.1 - 0.0069 16.3 0.0 0.034 14.1 0.0 1.9 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain MFS_1 PF07690.16 EGB12873.1 - 1e-26 93.7 39.8 1.3e-26 93.3 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UL17 PF17640.2 EGB12873.1 - 0.086 12.9 0.6 0.17 11.9 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized UL17 WTF PF03303.13 EGB12873.1 - 1.3 8.7 2.4 2.9 7.6 2.2 1.5 1 1 0 1 1 1 0 WTF protein TPR_7 PF13176.6 EGB12874.1 - 0.0036 17.2 8.2 0.12 12.4 0.4 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.7 EGB12874.1 - 1.1 9.1 3.5 1 9.1 0.2 2.6 3 0 0 3 3 3 0 PPR repeat HAD_2 PF13419.6 EGB12875.1 - 3.5e-18 66.3 0.0 9.2e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGB12875.1 - 1.1e-11 45.4 0.2 2.1e-11 44.5 0.2 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGB12875.1 - 3.1e-08 33.6 0.3 6.6e-08 32.5 0.2 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 EGB12875.1 - 0.027 14.9 0.3 0.061 13.7 0.3 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AMP-binding PF00501.28 EGB12876.1 - 9.4e-39 133.2 0.0 1.1e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGB12876.1 - 1.7e-06 28.9 0.3 3.8e-06 27.8 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 EGB12877.1 - 8.8e-46 156.5 4.5 1.2e-45 156.1 4.5 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGB12877.1 - 3.6e-13 49.6 1.1 7.6e-13 48.5 1.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGB12877.1 - 0.0088 15.4 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Herpes_UL43 PF05072.13 EGB12877.1 - 0.085 11.9 1.5 0.84 8.7 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus UL43 protein DUF2499 PF10693.9 EGB12878.1 - 5.4e-35 119.5 6.1 6e-35 119.4 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) Synaptobrevin PF00957.21 EGB12879.1 - 1.9e-14 53.2 0.4 3.4e-14 52.4 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGB12879.1 - 5e-08 32.9 0.0 9.2e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Thioredoxin PF00085.20 EGB12880.1 - 4.8e-21 74.7 0.0 5.4e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGB12880.1 - 0.00036 20.5 0.0 0.00038 20.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGB12880.1 - 0.0023 18.2 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGB12880.1 - 0.0046 17.4 0.1 0.0093 16.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGB12880.1 - 0.014 15.5 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 EGB12880.1 - 0.016 14.9 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 EGB12880.1 - 0.038 13.8 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 EGB12880.1 - 0.16 12.2 0.0 0.68 10.2 0.0 1.9 1 1 0 1 1 1 0 Glutaredoxin Sel1 PF08238.12 EGB12881.1 - 9.2e-28 96.1 8.7 1.4e-07 32.0 0.0 4.1 4 0 0 4 4 4 4 Sel1 repeat DUF977 PF06163.11 EGB12881.1 - 0.099 12.6 0.2 15 5.5 0.0 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF977) Response_reg PF00072.24 EGB12882.1 - 3.4e-09 36.9 0.0 1.1e-08 35.2 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain Dynamin_M PF01031.20 EGB12883.1 - 8.8e-67 225.3 0.0 1.1e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGB12883.1 - 2.8e-49 167.4 0.0 4.2e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB12883.1 - 0.00081 19.5 0.0 0.0043 17.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Tubulin PF00091.25 EGB12884.1 - 1.2e-40 139.8 0.3 1.8e-40 139.3 0.3 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EGB12884.1 - 9e-29 99.6 1.9 9e-29 99.6 1.9 2.1 2 0 0 2 2 2 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 EGB12884.1 - 0.2 11.5 4.7 0.16 11.9 1.3 2.4 1 1 1 2 2 2 0 NAD(P)H-binding cobW PF02492.19 EGB12885.1 - 6.1e-50 169.2 0.2 8e-50 168.9 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB12885.1 - 9.3e-24 83.2 0.0 2.1e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 EGB12885.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 EGB12885.1 - 0.015 14.3 0.5 3.3 6.6 0.0 2.7 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EGB12885.1 - 0.03 14.7 0.1 0.097 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGB12885.1 - 0.04 13.8 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EGB12885.1 - 0.053 13.1 0.1 9.3 5.7 0.6 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 EGB12885.1 - 0.061 13.2 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EGB12885.1 - 0.062 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGB12885.1 - 0.067 13.5 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EGB12885.1 - 0.084 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EGB12885.1 - 0.09 12.9 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EGB12885.1 - 0.093 13.2 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EGB12885.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_transf_17 PF04724.13 EGB12886.1 - 2.2e-09 36.8 0.0 4.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 17 UQ_con PF00179.26 EGB12888.1 - 1.4e-24 86.3 0.0 1.8e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGB12888.1 - 0.034 14.0 0.0 0.069 13.0 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EGB12888.1 - 0.037 14.3 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain Dynamin_N PF00350.23 EGB12889.1 - 1.4e-14 54.5 0.0 6.4e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGB12889.1 - 2.5e-06 27.6 0.0 0.0041 17.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGB12889.1 - 0.00048 20.1 0.4 0.0018 18.2 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EGB12889.1 - 0.0017 18.9 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 EGB12889.1 - 0.014 14.5 0.1 0.031 13.3 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EGB12889.1 - 0.019 15.2 0.4 0.065 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGB12889.1 - 0.042 13.2 0.6 0.091 12.1 0.6 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EGB12889.1 - 0.058 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EGB12889.1 - 0.11 13.1 0.0 0.38 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGB12889.1 - 0.11 13.0 0.5 0.21 12.0 0.5 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGB12889.1 - 0.61 9.7 2.6 0.27 10.8 0.2 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGB12889.1 - 0.61 10.2 0.0 0.61 10.2 0.0 2.7 4 0 0 4 4 4 0 AAA domain SIS_2 PF13580.6 EGB12890.1 - 0.47 10.5 6.9 0.063 13.3 2.1 2.0 2 0 0 2 2 2 0 SIS domain DUF3591 PF12157.8 EGB12891.1 - 2.2e-27 95.8 0.0 3.3e-15 55.7 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 EGB12891.1 - 2.6e-16 59.5 0.0 5.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain E1-E2_ATPase PF00122.20 EGB12892.1 - 1.4e-43 148.6 1.2 1.4e-43 148.6 1.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EGB12892.1 - 7.9e-10 38.3 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EGB12892.1 - 6.7e-05 23.3 0.9 0.00022 21.6 0.9 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Formyl_trans_N PF00551.19 EGB12893.1 - 1.3e-35 122.8 0.0 1.7e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Peptidase_M20 PF01546.28 EGB12894.1 - 1.6e-31 109.6 0.4 2.4e-31 109.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGB12894.1 - 4.8e-08 32.9 0.2 2.4e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain HATPase_c PF02518.26 EGB12896.1 - 0.0021 18.6 0.0 0.0024 18.4 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_1 PF00515.28 EGB12900.1 - 0.00028 20.6 1.0 0.0023 17.7 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGB12900.1 - 0.0031 17.6 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EGB12900.1 - 0.02 15.7 0.5 0.02 15.7 0.5 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB12900.1 - 0.16 12.1 6.4 0.2 11.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGB12900.1 - 4.5 7.6 7.8 0.52 10.5 0.3 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB12900.1 - 5.6 7.0 7.7 0.48 10.4 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGB12900.1 - 9.4 7.1 8.4 0.65 10.7 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat CA_like PF10563.9 EGB12901.1 - 4.5e-55 186.4 6.4 7.7e-55 185.6 6.4 1.4 1 0 0 1 1 1 1 Putative carbonic anhydrase cNMP_binding PF00027.29 EGB12902.1 - 1.2e-16 60.6 0.1 1.7e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 EGB12902.1 - 0.035 13.8 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Cupin domain GAS PF13851.6 EGB12903.1 - 5e-70 234.9 15.2 5e-70 234.9 15.2 3.7 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 EGB12903.1 - 0.032 14.3 8.1 1.6 8.8 1.4 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sod_Cu PF00080.20 EGB12904.1 - 1.4e-23 83.7 0.0 1.5e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SET PF00856.28 EGB12905.1 - 7.6e-08 32.9 0.1 8.4e-08 32.8 0.1 1.0 1 0 0 1 1 1 1 SET domain DUF4097 PF13349.6 EGB12906.1 - 0.0007 19.0 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Putative adhesin Methyltransf_25 PF13649.6 EGB12906.1 - 0.021 15.5 3.4 0.03 15.0 0.3 2.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGB12906.1 - 0.21 11.4 0.0 0.46 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2807 PF10988.8 EGB12906.1 - 4 7.2 10.7 0.22 11.3 3.9 2.3 2 0 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Sulfotransfer_2 PF03567.14 EGB12907.1 - 0.0047 16.9 0.0 0.0091 15.9 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Mon1 PF03164.14 EGB12908.1 - 8.8e-47 160.1 0.0 1.3e-46 159.6 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Tyrosinase PF00264.20 EGB12908.1 - 2.9e-14 53.9 0.1 8.2e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Common central domain of tyrosinase Importin_rep_4 PF18808.1 EGB12908.1 - 0.037 14.3 0.0 0.037 14.3 0.0 4.6 5 0 0 5 5 5 0 Importin repeat eIF3_N PF09440.10 EGB12909.1 - 1.6e-31 109.5 0.0 2e-30 105.9 0.0 2.4 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGB12909.1 - 2.4e-14 53.7 0.0 5.5e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_9 PF13371.6 EGB12909.1 - 0.018 15.2 0.2 0.018 15.2 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EGB12910.1 - 1.4e-18 67.2 0.0 4.8e-13 49.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family cobW PF02492.19 EGB12911.1 - 9.1e-57 191.5 1.1 1.2e-56 191.1 1.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGB12911.1 - 5.8e-18 64.6 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGB12911.1 - 8.4e-05 22.5 0.3 0.5 10.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGB12911.1 - 0.02 15.2 0.0 0.087 13.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGB12911.1 - 0.03 14.7 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGB12911.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EGB12911.1 - 0.098 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EGB12911.1 - 0.11 12.3 0.2 0.36 10.7 0.2 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RPE65 PF03055.15 EGB12911.1 - 0.17 11.1 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein AAA_11 PF13086.6 EGB12911.1 - 0.63 9.8 1.8 29 4.3 0.2 2.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EGB12911.1 - 2.9 8.3 5.8 21 5.5 5.8 2.2 1 1 0 1 1 1 0 AAA domain Pirin PF02678.16 EGB12912.1 - 2e-22 79.2 0.1 4e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGB12912.1 - 1.2e-12 48.1 0.0 2.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGB12912.1 - 0.00011 21.8 0.1 0.13 12.0 0.4 2.4 2 0 0 2 2 2 2 Cupin domain DUF2437 PF10370.9 EGB12912.1 - 0.0018 19.1 0.1 0.16 12.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) KOW PF00467.29 EGB12912.1 - 0.066 13.2 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 KOW motif Ank_2 PF12796.7 EGB12913.1 - 2.9e-05 24.6 1.0 6.6e-05 23.4 0.5 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB12913.1 - 4e-05 23.8 2.1 0.0007 19.9 0.3 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EGB12913.1 - 0.0046 17.4 0.1 0.018 15.5 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EGB12913.1 - 0.0084 16.5 0.0 0.063 13.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGB12913.1 - 0.016 15.8 0.0 0.053 14.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Fer4_14 PF13394.6 EGB12913.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Phage_int_SAM_1 PF02899.17 EGB12913.1 - 0.11 12.9 0.1 0.31 11.4 0.1 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ion_trans_2 PF07885.16 EGB12914.1 - 5.4e-09 35.9 0.4 5.4e-09 35.9 0.4 2.0 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 EGB12914.1 - 2.7e-06 26.8 0.7 2e-05 24.0 0.5 2.1 2 0 0 2 2 2 1 Ion transport protein Sds3 PF08598.11 EGB12914.1 - 0.031 14.3 0.3 0.065 13.2 0.0 1.6 2 0 0 2 2 2 0 Sds3-like DUF2852 PF11014.8 EGB12914.1 - 0.14 12.3 0.1 0.47 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SAP PF02037.27 EGB12916.1 - 0.0022 17.7 1.7 0.0062 16.3 1.7 1.8 1 0 0 1 1 1 1 SAP domain PKD PF00801.20 EGB12916.1 - 0.28 11.1 0.9 35 4.4 0.0 3.3 3 0 0 3 3 3 0 PKD domain LCD1 PF09798.9 EGB12916.1 - 0.53 8.7 2.1 0.76 8.2 2.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Ephrin_rec_like PF07699.13 EGB12918.1 - 0.00026 20.7 41.2 0.0054 16.5 0.5 6.7 4 2 3 7 7 7 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB12918.1 - 1.1 9.7 29.1 0.8 10.2 1.8 6.3 3 1 3 7 7 7 0 TNFR/NGFR cysteine-rich region Peptidase_C2 PF00648.21 EGB12919.1 - 9.5e-25 87.2 0.1 2.3e-24 85.9 0.1 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease HAP1_N PF04849.13 EGB12920.1 - 0.014 14.7 3.5 0.015 14.5 2.5 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region SF1-HH PF16275.5 EGB12920.1 - 0.15 12.4 1.8 0.15 12.4 0.3 1.7 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Endosulfine PF04667.17 EGB12922.1 - 0.062 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region ubiquitin PF00240.23 EGB12923.1 - 2.1e-88 290.1 6.2 1.2e-28 98.7 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EGB12923.1 - 1.8e-37 127.0 6.5 1.2e-11 44.3 0.1 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGB12923.1 - 3.7e-15 56.2 0.8 0.0029 18.0 0.0 3.7 3 1 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EGB12923.1 - 3.4e-12 46.1 0.0 0.0061 16.5 0.0 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGB12923.1 - 3e-09 37.0 0.0 0.026 14.6 0.0 3.9 2 2 1 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGB12923.1 - 3.4e-07 30.8 0.0 0.4 11.3 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGB12923.1 - 3.9e-06 27.1 0.1 1.1 9.7 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-like domain Big_3_3 PF13750.6 EGB12923.1 - 0.012 15.3 0.0 2.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Trypan_PARP PF05887.11 EGB12923.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ubiquitin_4 PF18036.1 EGB12923.1 - 0.016 15.2 6.9 47 4.1 0.1 5.5 4 2 2 6 6 6 0 Ubiquitin-like domain Raf1_HTH PF18579.1 EGB12923.1 - 0.052 13.3 0.2 34 4.2 0.0 3.1 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain EF-hand_8 PF13833.6 EGB12924.1 - 2.8e-10 39.9 0.2 5.9e-10 38.8 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EGB12924.1 - 3.6e-06 27.3 0.3 9.2e-06 26.0 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB12924.1 - 4.8e-06 25.8 0.1 0.0003 20.1 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGB12924.1 - 1.2e-05 24.8 0.2 0.017 15.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB12924.1 - 0.026 14.0 0.0 0.1 12.1 0.0 2.1 1 0 0 1 1 1 0 EF hand Spore_coat_CotO PF14153.6 EGB12924.1 - 0.12 12.4 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Spore coat protein CotO WD40 PF00400.32 EGB12925.1 - 1.4e-27 95.4 7.3 5.4e-10 39.7 0.4 3.0 3 0 0 3 3 3 3 WD domain, G-beta repeat PQQ_2 PF13360.6 EGB12925.1 - 1.6e-05 24.6 1.0 2e-05 24.3 1.0 1.1 1 0 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EGB12925.1 - 7.7e-05 22.9 0.0 0.072 13.4 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGB12925.1 - 9.1e-05 21.3 0.8 0.16 10.6 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF5570 PF17731.1 EGB12925.1 - 0.013 15.6 2.1 0.48 10.5 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5570) BppL_N PF18338.1 EGB12925.1 - 0.035 13.9 0.0 58 3.7 0.0 3.3 3 0 0 3 3 3 0 Lower baseplate protein N-terminal domain eIF3m_C_helix PF18005.1 EGB12925.1 - 0.049 13.3 1.4 9.2 6.1 0.0 3.2 3 0 0 3 3 3 0 eIF3 subunit M, C-terminal helix Ge1_WD40 PF16529.5 EGB12925.1 - 0.07 12.1 0.4 0.42 9.5 0.4 1.9 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGB12925.1 - 0.071 11.4 0.0 3.4 5.9 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 EGB12926.1 - 2.8e-66 217.8 41.0 8.4e-10 39.1 1.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12926.1 - 1.8e-10 41.0 1.3 0.51 10.7 0.0 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGB12926.1 - 2.7e-08 33.7 12.1 0.0052 16.4 1.9 3.9 1 1 3 4 4 4 4 PQQ-like domain DUF1513 PF07433.11 EGB12926.1 - 5.4e-08 32.3 3.0 0.12 11.4 0.1 3.5 1 1 3 4 4 4 3 Protein of unknown function (DUF1513) Nup160 PF11715.8 EGB12926.1 - 3.1e-06 26.1 14.9 1 7.9 0.2 5.9 1 1 5 6 6 6 4 Nucleoporin Nup120/160 BppL_N PF18338.1 EGB12926.1 - 0.00027 20.6 0.3 1.4e+02 2.5 0.0 6.1 6 0 0 6 6 6 0 Lower baseplate protein N-terminal domain Frtz PF11768.8 EGB12926.1 - 0.00077 17.9 0.0 32 2.6 0.0 5.1 2 2 2 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2222 PF09984.9 EGB12926.1 - 0.014 15.3 0.0 36 4.2 0.0 4.4 5 1 1 6 6 6 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) PQQ PF01011.21 EGB12926.1 - 0.014 15.3 0.1 1.4e+02 2.7 0.0 5.3 7 0 0 7 7 7 0 PQQ enzyme repeat IMP2_C PF18591.1 EGB12926.1 - 5.4 7.0 5.3 42 4.1 0.0 4.3 7 0 0 7 7 7 0 Immune Mapped Protein 2 (IMP2) C-terminal domain LBP_BPI_CETP PF01273.25 EGB12927.1 - 0.0036 16.9 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Ham1p_like PF01725.16 EGB12928.1 - 1.3e-53 181.7 0.0 1.5e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Ham1 family DUF285 PF03382.14 EGB12929.1 - 3.8e-38 130.0 11.4 4.1e-38 129.8 11.4 1.0 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 LepB_N PF18640.1 EGB12929.1 - 0.049 13.2 0.4 0.06 13.0 0.4 1.1 1 0 0 1 1 1 0 LepB N-terminal domain EGF_2 PF07974.13 EGB12930.1 - 1.5e-13 50.8 41.0 5.8e-06 26.6 8.7 4.2 4 0 0 4 4 4 4 EGF-like domain S_locus_glycop PF00954.20 EGB12930.1 - 0.00019 21.9 0.5 0.00019 21.9 0.5 2.7 3 0 0 3 3 3 1 S-locus glycoprotein domain EGF PF00008.27 EGB12930.1 - 0.00028 21.1 36.5 0.26 11.6 0.4 4.6 4 1 1 5 5 5 4 EGF-like domain Laminin_EGF PF00053.24 EGB12930.1 - 1.1 9.4 30.1 0.81 9.9 12.3 3.4 2 1 1 3 3 3 0 Laminin EGF domain PCI PF01399.27 EGB12931.1 - 5.2e-17 62.3 0.4 1.4e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 PCI domain UbiA PF01040.18 EGB12932.1 - 7.7e-25 87.6 18.1 7.7e-25 87.6 18.1 2.4 2 1 0 2 2 2 1 UbiA prenyltransferase family DnaJ PF00226.31 EGB12932.1 - 1.4e-19 70.0 0.1 2.3e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain UPF0121 PF03661.13 EGB12933.1 - 1.9e-14 53.7 0.0 4.8e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_2 PF07719.17 EGB12933.1 - 1.8e-11 43.2 8.3 4.3e-05 23.3 3.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12933.1 - 2.9e-10 39.5 9.6 5.6e-06 25.9 2.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB12933.1 - 1.1e-06 28.2 1.7 0.0024 17.5 0.8 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 EGB12933.1 - 1.7e-05 24.7 3.9 0.0024 17.9 0.6 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGB12933.1 - 9.4e-05 23.0 7.6 0.036 14.7 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3808 PF10300.9 EGB12933.1 - 0.0044 15.8 0.2 0.0062 15.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 EGB12933.1 - 0.031 14.8 6.8 1.4 9.5 0.2 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB12933.1 - 0.042 14.0 2.6 0.061 13.5 1.6 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGB12933.1 - 0.047 14.1 1.4 13 6.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB12933.1 - 0.056 14.3 8.6 0.13 13.1 3.8 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB12933.1 - 0.059 13.4 0.4 0.27 11.3 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB12933.1 - 0.58 10.5 8.9 0.48 10.7 3.5 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat ABC1 PF03109.16 EGB12934.1 - 3.1e-20 72.5 0.0 4.8e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGB12934.1 - 0.00024 21.1 4.1 0.00024 21.1 4.1 3.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGB12934.1 - 0.083 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain DNA_pol_phi PF04931.13 EGB12935.1 - 0.082 11.0 3.2 0.18 9.9 3.2 1.5 1 0 0 1 1 1 0 DNA polymerase phi DUF4054 PF13262.6 EGB12935.1 - 0.25 11.4 3.5 0.2 11.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Pox_Ag35 PF03286.14 EGB12935.1 - 9.4 6.0 7.7 3 7.6 2.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein ABC_tran PF00005.27 EGB12936.1 - 5.7e-08 33.4 0.0 0.018 15.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 EGB12936.1 - 0.046 13.5 0.1 8.3 6.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EGB12936.1 - 0.23 10.2 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class ABC2_membrane PF01061.24 EGB12936.1 - 0.43 10.0 10.5 4.8 6.5 5.2 2.3 2 0 0 2 2 2 0 ABC-2 type transporter Glyco_hydro_76 PF03663.14 EGB12938.1 - 1.8e-38 133.0 15.0 2.2e-38 132.8 15.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGB12938.1 - 4.7e-05 22.6 0.4 0.033 13.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EGB12938.1 - 0.026 14.0 0.2 0.06 12.8 0.0 1.6 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 EGB12938.1 - 0.043 12.3 0.0 1.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Pkinase PF00069.25 EGB12939.1 - 3.3e-62 210.3 0.0 4.4e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB12939.1 - 1.1e-36 126.5 0.0 1.7e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGB12939.1 - 1.3e-19 70.4 5.9 1.7e-09 38.0 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB12939.1 - 1.2e-18 65.3 3.4 0.0015 18.3 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGB12939.1 - 1.5e-18 64.8 10.7 9.9e-05 21.6 0.6 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EGB12939.1 - 8.7e-16 57.5 9.5 5.9e-07 29.2 0.3 5.3 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EGB12939.1 - 3.8e-11 42.0 4.8 0.12 12.0 0.0 4.5 4 0 0 4 4 4 4 EF hand Kdo PF06293.14 EGB12939.1 - 7.8e-07 28.6 0.3 1.7e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGB12939.1 - 2.4e-05 23.3 0.0 5.8e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase EFhand_Ca_insen PF08726.10 EGB12939.1 - 3.5e-05 23.8 0.4 0.27 11.4 0.2 2.8 2 0 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_4 PF12763.7 EGB12939.1 - 0.001 19.0 0.3 0.92 9.5 0.0 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGB12939.1 - 0.0012 19.1 0.3 0.53 10.6 0.0 3.0 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 EGB12939.1 - 0.0017 18.4 0.0 0.051 13.5 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGB12939.1 - 0.0035 16.3 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGB12939.1 - 0.0089 15.4 0.0 0.029 13.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like EcKinase PF02958.20 EGB12939.1 - 0.043 13.1 0.3 0.93 8.7 0.0 2.4 2 0 0 2 2 2 0 Ecdysteroid kinase Choline_kinase PF01633.20 EGB12939.1 - 0.075 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF5580 PF17743.1 EGB12939.1 - 0.089 11.3 0.0 2.6 6.5 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Lip_prot_lig_C PF10437.9 EGB12939.1 - 0.11 12.4 0.4 19 5.3 0.0 3.5 2 1 2 4 4 4 0 Bacterial lipoate protein ligase C-terminus PAS_9 PF13426.7 EGB12940.1 - 4.6e-16 59.0 0.0 5.2e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EGB12940.1 - 6.5e-06 26.4 0.0 7.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EGB12940.1 - 2.5e-05 24.5 0.0 2.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EGB12940.1 - 0.018 15.0 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 PAS fold PAS_12 PF18095.1 EGB12940.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.3 1 1 0 1 1 1 0 UPF0242 C-terminal PAS-like domain FKBP_C PF00254.28 EGB12941.1 - 1.3e-17 63.9 0.0 1.4e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_5 PF13202.6 EGB12942.1 - 7.9e-05 22.0 0.4 0.00015 21.1 0.4 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGB12942.1 - 9.9e-05 22.0 0.5 0.00021 21.0 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EGB12942.1 - 0.00016 21.0 0.4 0.0003 20.1 0.4 1.5 1 0 0 1 1 1 1 EF hand MtrD PF04207.12 EGB12942.1 - 0.044 13.5 0.1 0.044 13.5 0.1 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D EF-hand_7 PF13499.6 EGB12942.1 - 0.06 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 EGB12942.1 - 0.092 12.6 0.4 0.18 11.7 0.4 1.5 1 0 0 1 1 1 0 EF-hand domain pair VCBS PF13517.6 EGB12943.1 - 3.1e-23 82.1 35.9 1.7e-11 44.6 6.5 4.3 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGB12943.1 - 5.6e-13 48.8 57.9 0.002 18.2 2.1 6.5 6 0 0 6 6 6 5 FG-GAP repeat DEC-1_N PF04625.13 EGB12943.1 - 8.7e-06 25.0 43.4 0.11 11.5 3.1 4.6 4 0 0 4 4 4 4 DEC-1 protein, N-terminal region BBS2_Mid PF14783.6 EGB12943.1 - 0.028 14.5 0.3 29 4.8 0.0 4.2 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region BBS1 PF14779.6 EGB12943.1 - 0.38 10.1 1.7 14 5.0 0.0 3.9 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 1 Itfg2 PF15907.5 EGB12943.1 - 0.86 8.6 4.0 9.7 5.1 0.0 3.8 5 0 0 5 5 5 0 Integrin-alpha FG-GAP repeat-containing protein 2 START PF01852.19 EGB12943.1 - 7.1 6.0 17.0 9.4 5.6 0.2 5.8 6 0 0 6 6 6 0 START domain FAD_binding_3 PF01494.19 EGB12945.1 - 2.3e-20 73.2 2.7 1.6e-19 70.4 2.5 2.4 2 1 0 2 2 2 1 FAD binding domain Ccdc124 PF06244.12 EGB12945.1 - 2.2e-18 67.0 17.8 4.2e-17 62.9 17.7 2.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Fasciclin PF02469.22 EGB12945.1 - 2e-08 34.5 0.0 3.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain NAD_binding_8 PF13450.6 EGB12945.1 - 1.3e-05 25.3 0.5 5e-05 23.5 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB12945.1 - 4.7e-05 23.1 1.0 4.7e-05 23.1 1.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGB12945.1 - 0.0003 20.1 0.5 0.00065 19.0 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGB12945.1 - 0.0044 16.2 0.9 0.0068 15.5 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DnaJ_CXXCXGXG PF00684.19 EGB12945.1 - 0.0048 17.2 0.3 0.011 16.1 0.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Pyr_redox PF00070.27 EGB12945.1 - 0.046 14.3 3.5 0.15 12.7 2.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HMG_box PF00505.19 EGB12945.1 - 0.07 13.6 0.1 0.07 13.6 0.1 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box AAA PF00004.29 EGB12947.1 - 9.5e-29 100.5 0.0 1.1e-12 48.6 0.0 4.7 4 1 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EGB12947.1 - 1.1e-14 54.3 16.7 8.4e-08 32.3 0.2 4.2 4 0 0 4 4 3 3 AAA lid domain AAA_30 PF13604.6 EGB12947.1 - 1.2e-07 31.7 4.3 0.1 12.3 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 EGB12947.1 - 4.9e-07 30.1 1.6 1.4 9.2 0.0 6.1 4 3 0 4 4 4 1 AAA domain AAA_19 PF13245.6 EGB12947.1 - 2.2e-06 28.1 0.1 0.75 10.1 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EGB12947.1 - 1.6e-05 24.9 0.8 0.7 9.9 0.0 3.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGB12947.1 - 2.7e-05 23.6 0.3 0.38 10.1 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGB12947.1 - 6.7e-05 23.1 1.4 0.32 11.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain CAP_GLY PF01302.25 EGB12947.1 - 0.00025 21.0 0.0 0.00063 19.7 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain RNA_helicase PF00910.22 EGB12947.1 - 0.0033 17.8 0.1 6.6 7.2 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 EGB12947.1 - 0.0041 17.7 1.7 4.4 7.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EGB12947.1 - 0.0066 16.0 0.1 6.7 6.2 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGB12947.1 - 0.013 15.8 2.5 2.4 8.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGB12947.1 - 0.015 15.1 0.5 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 EGB12947.1 - 0.024 14.4 0.0 9.2 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain INCENP_ARK-bind PF03941.15 EGB12947.1 - 0.028 14.4 0.5 0.028 14.4 0.5 3.1 4 0 0 4 4 2 0 Inner centromere protein, ARK binding region Zot PF05707.12 EGB12947.1 - 0.051 13.2 0.9 1.3 8.6 0.0 3.3 4 1 1 5 5 5 0 Zonular occludens toxin (Zot) Guanylate_cyc_2 PF09778.9 EGB12947.1 - 0.14 11.5 0.0 6.9 6.0 0.0 2.6 3 0 0 3 3 3 0 Guanylylate cyclase IstB_IS21 PF01695.17 EGB12947.1 - 0.19 11.5 0.1 26 4.5 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_16 PF13191.6 EGB12947.1 - 0.37 11.2 8.3 24 5.3 0.0 4.7 5 0 0 5 5 3 0 AAA ATPase domain AAA_17 PF13207.6 EGB12947.1 - 1.3 9.4 5.1 5.5 7.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 EGB12947.1 - 1.4 8.1 6.3 47 3.1 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) DUF4611 PF15387.6 EGB12947.1 - 3 8.1 4.5 0.77 10.0 0.2 2.3 3 0 0 3 3 1 0 Domain of unknown function (DUF4611) RINGv PF12906.7 EGB12948.1 - 7.2e-13 48.4 5.3 1.3e-12 47.6 5.3 1.4 1 0 0 1 1 1 1 RING-variant domain BAH PF01426.18 EGB12948.1 - 0.00047 20.0 0.0 0.00083 19.2 0.0 1.3 1 0 0 1 1 1 1 BAH domain FANCL_C PF11793.8 EGB12948.1 - 0.062 13.5 2.9 0.16 12.2 2.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EGB12948.1 - 0.23 11.4 8.9 0.036 14.0 4.8 1.9 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 EGB12948.1 - 0.4 11.0 6.1 0.85 10.0 6.1 1.6 1 0 0 1 1 1 0 Ring finger domain Mg_chelatase PF01078.21 EGB12949.1 - 1.5e-15 57.2 0.2 1.1e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_lid_2 PF17863.1 EGB12949.1 - 3.4e-14 52.4 1.0 8.3e-14 51.2 0.2 2.1 2 0 0 2 2 2 1 AAA lid domain VWA_2 PF13519.6 EGB12949.1 - 5.8e-12 46.2 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activat PF00158.26 EGB12949.1 - 3.4e-07 30.1 0.0 0.0029 17.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain MCM PF00493.23 EGB12949.1 - 6.7e-07 28.6 0.1 6.3e-06 25.4 0.0 2.2 2 1 0 2 2 2 1 MCM P-loop domain Sigma54_activ_2 PF14532.6 EGB12949.1 - 5.2e-06 26.6 0.0 0.033 14.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain VWA PF00092.28 EGB12949.1 - 9.6e-06 25.9 0.0 1.7e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 EGB12949.1 - 1e-05 25.6 0.1 0.0017 18.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) VWA_CoxE PF05762.14 EGB12949.1 - 0.0076 15.7 0.4 0.017 14.6 0.4 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein AAA_7 PF12775.7 EGB12949.1 - 0.01 15.4 0.0 0.45 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGB12949.1 - 0.012 16.0 0.1 0.012 16.0 0.1 2.6 3 1 0 3 3 2 0 AAA ATPase domain DUF444 PF04285.12 EGB12949.1 - 0.017 14.2 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Mito_fiss_reg PF05308.11 EGB12949.1 - 0.14 12.2 5.1 0.23 11.5 5.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_22 PF13401.6 EGB12949.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain 5_nucleotid_C PF02872.18 EGB12950.1 - 1.9e-10 41.2 0.0 3e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Mito_carr PF00153.27 EGB12950.1 - 2.8e-09 36.8 8.6 0.00048 20.0 0.1 4.8 2 2 2 4 4 4 3 Mitochondrial carrier protein Metallophos PF00149.28 EGB12950.1 - 1.9e-06 28.5 0.0 3.6e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 EGB12950.1 - 0.00099 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap MyTH4 PF00784.17 EGB12951.1 - 5.2e-14 52.7 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 MyTH4 domain C2 PF00168.30 EGB12951.1 - 2e-07 31.2 0.0 5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain WD40 PF00400.32 EGB12952.1 - 8.8e-42 140.3 9.0 4.6e-10 39.9 0.9 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB12952.1 - 4.4e-13 49.3 0.1 0.012 15.9 0.0 4.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB12952.1 - 1.1e-09 37.7 5.8 0.0078 15.2 0.1 4.9 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGB12952.1 - 0.00015 21.6 0.0 1.6 8.8 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat SGL PF08450.12 EGB12952.1 - 0.001 18.7 0.8 0.0047 16.5 0.2 2.1 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 EGB12952.1 - 0.037 12.6 0.1 2.1 6.8 0.3 2.4 1 1 2 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.8 EGB12952.1 - 0.067 11.8 7.1 2.1 6.9 0.0 3.9 2 1 2 4 4 4 0 Nucleoporin Nup120/160 DPPIV_N PF00930.21 EGB12952.1 - 0.21 10.3 0.3 17 4.0 0.0 3.0 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1707 PF08044.11 EGB12952.1 - 0.23 11.6 4.8 2.9 8.0 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) DUF1902 PF08972.11 EGB12952.1 - 5.4 7.1 9.5 4 7.5 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) TruB_C PF09142.11 EGB12952.1 - 5.6 6.8 11.1 4 7.3 0.5 4.3 4 2 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal PQQ_3 PF13570.6 EGB12952.1 - 8.5 7.0 10.4 14 6.3 1.0 3.7 4 0 0 4 4 4 0 PQQ-like domain LRR_6 PF13516.6 EGB12953.1 - 5.9e-19 66.5 14.7 0.17 12.0 0.1 10.5 10 0 0 10 10 10 6 Leucine Rich repeat PA PF02225.22 EGB12953.1 - 6.1e-09 35.8 1.1 6.1e-09 35.8 1.1 2.4 2 0 0 2 2 2 1 PA domain LRR_4 PF12799.7 EGB12953.1 - 0.001 19.4 0.0 14 6.3 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) Peptidase_C1 PF00112.23 EGB12954.1 - 3.1e-58 197.4 0.3 3.7e-58 197.2 0.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB12954.1 - 2.3e-07 31.2 0.2 3.3e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB12954.1 - 0.028 13.2 0.7 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family CAP_N PF01213.19 EGB12954.1 - 2.3 7.6 4.2 3.4 7.1 4.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mog1 PF04603.12 EGB12955.1 - 8.8e-25 87.7 0.0 3.3e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 Ran-interacting Mog1 protein Ribosomal_L29 PF00831.23 EGB12955.1 - 2 8.5 8.2 4.4 7.4 0.5 3.5 2 1 0 2 2 2 0 Ribosomal L29 protein bZIP_1 PF00170.21 EGB12955.1 - 6.2 7.0 13.8 2.6 8.2 0.2 3.6 4 0 0 4 4 4 0 bZIP transcription factor NUDIX PF00293.28 EGB12956.1 - 9.9e-17 61.2 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain EF-hand_7 PF13499.6 EGB12957.1 - 5.4e-10 39.6 0.0 4.2e-09 36.7 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain pair 5_nucleotid_C PF02872.18 EGB12957.1 - 1.4e-09 38.3 0.0 3.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain EF-hand_5 PF13202.6 EGB12957.1 - 3.8e-07 29.3 0.0 0.026 14.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 EGB12957.1 - 8e-07 28.2 0.0 0.033 13.7 0.0 2.9 3 0 0 3 3 3 2 EF hand Metallophos PF00149.28 EGB12957.1 - 0.00048 20.7 0.0 0.00095 19.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.6 EGB12957.1 - 0.00088 19.0 0.1 0.36 10.9 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 EGB12957.1 - 0.17 11.8 0.0 0.75 9.7 0.0 2.1 3 1 0 3 3 3 0 EF-hand domain pair EamA PF00892.20 EGB12958.1 - 1.2e-12 48.2 16.9 5.8e-08 33.0 5.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family tRNA-synt_2b PF00587.25 EGB12959.1 - 1.9e-21 76.8 0.0 3.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 EGB12959.1 - 5.7e-19 68.1 0.1 1.2e-18 67.1 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EGB12959.1 - 4.7e-15 55.5 0.0 9.1e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 EGB12959.1 - 0.0004 20.5 5.7 0.0014 18.8 5.7 2.0 1 1 0 1 1 1 1 WHEP-TRS domain Co_AT_N PF12557.8 EGB12959.1 - 3.5 7.7 9.0 9 6.3 9.0 1.7 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal ACP_syn_III_C PF08541.10 EGB12960.1 - 7.8e-37 125.3 0.1 5.1e-36 122.7 0.1 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGB12960.1 - 2e-29 101.3 1.6 2e-29 101.3 1.6 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EGB12960.1 - 5.4e-08 32.5 0.2 2.8e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Chal_sti_synt_N PF00195.19 EGB12960.1 - 0.0019 17.7 1.6 0.0057 16.1 1.6 1.7 1 1 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Thiolase_C PF02803.18 EGB12960.1 - 0.0042 16.7 0.4 0.11 12.2 0.2 2.7 2 1 0 2 2 2 1 Thiolase, C-terminal domain SpoVAD PF07451.11 EGB12960.1 - 0.018 13.8 0.3 0.063 12.0 0.2 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 EGB12960.1 - 0.11 12.5 0.3 3.9 7.5 0.0 3.0 3 1 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain DUF2059 PF09832.9 EGB12961.1 - 0.064 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) HECT PF00632.25 EGB12962.1 - 6.1e-66 223.0 0.0 7.1e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LPAM_1 PF08139.12 EGB12962.1 - 0.71 10.5 4.1 2.5 8.8 4.1 2.0 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site AAA PF00004.29 EGB12963.1 - 2.8e-36 124.9 0.0 3.2e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGB12963.1 - 1.2e-07 32.0 0.0 1.7e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGB12963.1 - 8.7e-07 29.5 0.5 5.4e-06 26.9 0.5 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGB12963.1 - 1e-06 29.1 0.0 0.00019 21.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 EGB12963.1 - 5.3e-06 26.7 0.0 6.9e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGB12963.1 - 1.9e-05 25.2 0.0 2.3e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGB12963.1 - 2.2e-05 24.5 0.1 4.4e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EGB12963.1 - 2.4e-05 24.3 0.0 3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EGB12963.1 - 6.2e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGB12963.1 - 0.00035 20.8 0.0 0.00048 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGB12963.1 - 0.00044 20.6 0.0 0.00063 20.1 0.0 1.4 1 1 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EGB12963.1 - 0.00077 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 EGB12963.1 - 0.0008 19.4 0.0 0.002 18.1 0.0 1.6 1 1 0 2 2 2 1 NACHT domain TsaE PF02367.17 EGB12963.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGB12963.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGB12963.1 - 0.002 18.7 0.0 0.0023 18.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_3 PF07726.11 EGB12963.1 - 0.0038 17.1 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGB12963.1 - 0.0054 16.8 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGB12963.1 - 0.012 15.2 0.6 0.12 12.0 0.0 2.1 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGB12963.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 EGB12963.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EGB12963.1 - 0.03 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 EGB12963.1 - 0.042 13.6 0.1 0.093 12.4 0.0 1.5 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 EGB12963.1 - 0.056 13.9 0.0 0.13 12.7 0.0 1.6 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGB12963.1 - 0.058 13.1 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EGB12963.1 - 0.063 13.1 0.0 0.063 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGB12963.1 - 0.067 12.4 0.0 0.26 10.5 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 EGB12963.1 - 0.11 11.8 0.0 5.5 6.4 0.0 2.3 2 1 1 3 3 3 0 Bacterial TniB protein AAA_24 PF13479.6 EGB12963.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGB12963.1 - 0.25 11.2 0.0 1.4 8.8 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea VCBS PF13517.6 EGB12964.1 - 2.3e-17 63.4 34.9 2e-09 37.9 8.6 3.6 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.18 EGB12964.1 - 0.083 13.1 15.1 6.1 7.1 0.7 4.2 4 0 0 4 4 4 0 Dockerin type I domain TMP_2 PF06791.13 EGB12964.1 - 0.83 9.3 4.0 3.4 7.3 4.0 2.0 1 0 0 1 1 1 0 Prophage tail length tape measure protein EF-hand_5 PF13202.6 EGB12964.1 - 5 6.8 16.8 23 4.7 0.2 3.8 3 0 0 3 3 3 0 EF hand zf-CCHC_4 PF14392.6 EGB12965.1 - 0.0072 16.0 22.8 0.049 13.4 0.1 5.0 4 1 1 5 5 5 3 Zinc knuckle zf-CCHC PF00098.23 EGB12965.1 - 0.0081 16.2 4.7 0.022 14.8 1.4 5.4 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.6 EGB12965.1 - 0.057 13.4 1.1 0.057 13.4 1.1 4.0 2 2 2 4 4 4 0 Zinc knuckle SAP18 PF06487.12 EGB12966.1 - 7.7e-33 113.6 0.0 9.4e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Cpn60_TCP1 PF00118.24 EGB12967.1 - 3.5e-144 481.1 0.1 4e-144 480.9 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.22 EGB12968.1 - 2.5e-19 69.7 0.1 3e-19 69.5 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TPR_2 PF07719.17 EGB12969.1 - 1.4e-05 24.9 8.5 0.12 12.6 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB12969.1 - 1.4e-05 24.7 0.9 0.00013 21.6 0.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 EGB12969.1 - 0.00048 20.7 8.7 0.00048 20.7 8.7 7.2 5 1 2 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGB12969.1 - 0.0011 18.7 6.5 0.12 12.3 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB12969.1 - 0.0021 18.1 1.8 0.18 12.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB12969.1 - 0.011 16.1 0.1 2.4 8.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGB12969.1 - 0.03 14.5 9.0 0.058 13.6 3.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGB12969.1 - 0.033 15.0 1.0 0.033 15.0 1.0 5.3 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGB12969.1 - 0.2 11.7 1.4 0.59 10.3 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGB12969.1 - 0.2 11.9 7.5 0.22 11.8 0.6 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB12969.1 - 0.22 12.0 6.3 0.19 12.3 2.9 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Arylsulfotrans PF05935.11 EGB12970.1 - 1.7e-11 43.7 0.4 3.4e-11 42.7 0.4 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) OTU PF02338.19 EGB12972.1 - 0.00053 20.5 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Rhodanese PF00581.20 EGB12973.1 - 1.2e-09 38.6 0.0 1.5e-06 28.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF4126 PF13548.6 EGB12973.1 - 0.012 15.3 1.3 0.018 14.7 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) DUF442 PF04273.13 EGB12973.1 - 0.13 12.3 1.0 0.34 11.0 1.0 1.7 1 1 0 1 1 1 0 Putative phosphatase (DUF442) HMG_CoA_synt_N PF01154.17 EGB12974.1 - 7.1e-69 231.1 0.0 9.8e-69 230.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EGB12974.1 - 1.6e-59 201.8 0.0 2.2e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 EGB12974.1 - 0.0036 17.4 0.1 0.015 15.4 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal WW PF00397.26 EGB12976.1 - 1.6e-07 31.3 2.7 1.6e-07 31.3 2.7 1.5 2 0 0 2 2 2 1 WW domain WH2 PF02205.20 EGB12976.1 - 0.00018 21.2 0.4 0.00068 19.4 0.4 2.0 1 0 0 1 1 1 1 WH2 motif Sugarporin_N PF11471.8 EGB12976.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension HEAT_2 PF13646.6 EGB12977.1 - 0.0014 18.9 1.2 0.03 14.7 0.1 3.0 2 1 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EGB12977.1 - 0.01 16.3 0.1 0.099 13.2 0.0 2.6 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 EGB12977.1 - 0.019 15.2 0.3 0.25 11.7 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat COX6B PF02297.17 EGB12978.1 - 2.5e-08 34.0 7.3 5.5e-08 32.9 7.3 1.5 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb Glucosamine_iso PF01182.20 EGB12980.1 - 1.7e-27 96.8 1.4 3.7e-18 66.2 0.1 2.0 2 0 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AAA_lid_6 PF17866.1 EGB12981.1 - 1.5e-14 53.9 0.4 3.1e-14 52.9 0.4 1.5 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 EGB12981.1 - 5e-14 52.9 0.0 2.7e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGB12981.1 - 0.0002 21.6 0.5 0.34 11.2 0.3 2.6 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGB12981.1 - 0.00039 19.9 0.4 0.0029 17.0 0.2 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGB12981.1 - 0.00087 19.8 0.4 0.018 15.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGB12981.1 - 0.0034 17.4 0.1 0.0086 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EGB12981.1 - 0.0045 17.3 0.5 0.014 15.7 0.4 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGB12981.1 - 0.0056 16.7 0.0 0.019 15.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EGB12981.1 - 0.0057 16.3 0.1 0.7 9.5 0.1 2.5 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) NTPase_1 PF03266.15 EGB12981.1 - 0.0076 16.2 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 NTPase CbiA PF01656.23 EGB12981.1 - 0.0089 16.1 0.4 0.045 13.8 0.1 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 EGB12981.1 - 0.012 15.8 0.7 0.028 14.7 0.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGB12981.1 - 0.013 15.3 0.1 0.031 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGB12981.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGB12981.1 - 0.02 15.3 0.0 0.047 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.10 EGB12981.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 EGB12981.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EGB12981.1 - 0.043 14.2 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 EGB12981.1 - 0.044 13.5 0.1 0.12 12.1 0.1 1.9 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MazG PF03819.17 EGB12981.1 - 0.055 13.7 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain APS_kinase PF01583.20 EGB12981.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MeaB PF03308.16 EGB12981.1 - 0.083 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 EGB12981.1 - 0.1 11.8 2.8 0.33 10.1 0.9 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 EGB12981.1 - 0.11 11.4 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Ribosomal_L11 PF00298.19 EGB12981.1 - 0.15 12.6 0.0 17 6.0 0.0 3.2 4 0 0 4 4 4 0 Ribosomal protein L11, RNA binding domain AAA_25 PF13481.6 EGB12981.1 - 0.23 11.0 0.7 0.63 9.6 0.3 1.8 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 EGB12981.1 - 0.24 11.1 0.1 0.56 9.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pro_isomerase PF00160.21 EGB12982.1 - 6.7e-27 94.7 0.0 7.9e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NTPase_I-T PF01931.18 EGB12984.1 - 1.6e-49 167.8 0.0 2.9e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF84 Cyt-b5 PF00173.28 EGB12985.1 - 1.3e-12 47.7 0.1 1.5e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PhyH PF05721.13 EGB12986.1 - 4.4e-30 105.5 0.0 5.1e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CDP-OH_P_transf PF01066.21 EGB12987.1 - 2.2e-09 37.9 1.8 2.5e-09 37.8 0.3 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Prion_bPrPp PF11587.8 EGB12987.1 - 0.016 15.0 0.5 0.039 13.8 0.5 1.6 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal EAP30 PF04157.16 EGB12988.1 - 1.9e-22 79.7 0.3 3.6e-22 78.8 0.3 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family Fumble PF03630.14 EGB12988.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Fumble MACPF PF01823.19 EGB12989.1 - 2.2e-19 70.4 0.0 1.1e-15 58.3 0.0 2.1 2 0 0 2 2 2 2 MAC/Perforin domain Ricin_B_lectin PF00652.22 EGB12989.1 - 2.1e-15 57.1 0.7 4.2e-05 23.8 0.1 4.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGB12989.1 - 5.8e-05 23.7 7.0 0.074 13.8 0.2 3.6 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like EGF_2 PF07974.13 EGB12989.1 - 0.0015 18.9 12.4 0.0084 16.5 12.4 2.5 1 0 0 1 1 1 1 EGF-like domain CBS PF00571.28 EGB12990.1 - 7.3e-05 23.1 8.0 0.57 10.7 0.1 4.1 4 0 0 4 4 4 3 CBS domain Peptidase_S10 PF00450.22 EGB12991.1 - 2.1e-111 373.3 0.0 2.4e-111 373.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EGB12991.1 - 0.0016 19.0 6.5 0.35 11.5 6.3 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_M1 PF01433.20 EGB12992.1 - 5.3e-46 156.9 0.0 7.5e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGB12992.1 - 2.6e-32 111.3 0.0 6.7e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGB12992.1 - 7.2e-15 55.6 0.0 1.1e-14 55.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 EGB12992.1 - 0.052 13.3 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Ion_trans_2 PF07885.16 EGB12994.1 - 1.7e-15 56.7 3.9 2e-15 56.5 3.9 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGB12994.1 - 3.9e-11 42.6 0.2 4.1e-11 42.6 0.2 1.0 1 0 0 1 1 1 1 Ion transport protein NAP PF00956.18 EGB12995.1 - 5.9e-65 219.1 0.1 6.8e-65 218.9 0.1 1.0 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DNA_pol_phi PF04931.13 EGB12995.1 - 1.1 7.3 11.5 1.4 6.9 11.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_17 PF00332.18 EGB12996.1 - 6.8e-18 65.3 0.0 7.4e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 PYC_OADA PF02436.18 EGB12997.1 - 2.2e-54 184.2 0.0 3.6e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Conserved carboxylase domain Carboxyl_trans PF01039.22 EGB12997.1 - 3.6e-25 88.6 1.4 1.2e-24 86.9 1.4 1.6 1 1 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.14 EGB12997.1 - 4.6e-22 78.4 0.0 9.6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HMGL-like PF00682.19 EGB12997.1 - 2.5e-21 76.4 0.3 6.1e-21 75.2 0.3 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGB12997.1 - 1.3e-11 44.2 0.5 2.8e-11 43.1 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGB12997.1 - 0.021 14.6 0.3 0.2 11.5 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like DUF1623 PF07785.11 EGB12997.1 - 0.43 10.8 1.3 14 6.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1623) DAZAP2 PF11029.8 EGB12997.1 - 6.3 7.7 7.6 8.7 7.3 3.7 2.8 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) SNARE_assoc PF09335.11 EGB12998.1 - 3.4e-17 63.0 3.1 3.4e-17 63.0 3.1 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein CwsA PF10814.8 EGB12998.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.8 3 0 0 3 3 3 0 Cell wall synthesis protein CwsA XPC-binding PF09280.11 EGB12998.1 - 2.9 7.7 12.2 2.7 7.8 0.0 4.1 5 0 0 5 5 5 0 XPC-binding domain partial_CstF PF15861.5 EGB12998.1 - 5.9 6.8 6.8 6.2 6.7 0.1 2.7 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain DUF1336 PF07059.12 EGB13000.1 - 4.2e-53 180.7 0.0 4.8e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) tRNA-synt_1d PF00750.19 EGB13001.1 - 3.3e-113 378.2 0.0 4.5e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGB13001.1 - 1e-24 87.0 0.5 1.9e-24 86.1 0.5 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGB13001.1 - 6.6e-14 52.3 0.0 1.6e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 EGB13001.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGB13001.1 - 0.0089 14.8 0.0 0.019 13.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGB13001.1 - 0.015 13.6 0.1 0.022 13.0 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) TrpP PF17099.5 EGB13002.1 - 0.025 14.4 0.0 0.074 12.8 0.0 1.6 1 1 0 1 1 1 0 Tryptophan transporter TrpP DnaJ_C PF01556.18 EGB13004.1 - 2e-40 138.3 0.0 2.7e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGB13004.1 - 9.1e-27 93.0 2.1 1.5e-26 92.3 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain Cupin_4 PF08007.12 EGB13005.1 - 7.4e-23 81.5 0.0 1.2e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein TRAM_LAG1_CLN8 PF03798.16 EGB13005.1 - 8.5e-10 38.7 9.9 2e-09 37.4 9.9 1.6 1 0 0 1 1 1 1 TLC domain DUF563 PF04577.14 EGB13005.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Cupin_8 PF13621.6 EGB13005.1 - 0.0034 17.1 0.0 0.039 13.7 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain CitMHS PF03600.16 EGB13006.1 - 2.3e-24 86.1 40.3 2.1e-16 60.0 17.1 2.7 2 1 0 2 2 2 2 Citrate transporter RGS PF00615.19 EGB13006.1 - 3.7e-12 46.6 0.2 6.5e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_25 PF13649.6 EGB13006.1 - 2.7e-08 34.4 0.1 7e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB13006.1 - 3.8e-06 27.4 0.2 1.5e-05 25.5 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB13006.1 - 0.00012 22.8 0.0 0.00042 21.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB13006.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGB13006.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 EGB13006.1 - 0.08 12.7 0.1 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TrkA_C PF02080.21 EGB13006.1 - 0.084 12.7 0.0 0.81 9.6 0.0 2.7 3 0 0 3 3 3 0 TrkA-C domain Cyt-b5 PF00173.28 EGB13007.1 - 2e-09 37.5 0.1 2.2e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CCHC PF00098.23 EGB13008.1 - 1.2e-08 34.6 2.0 1.8e-08 34.1 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGB13008.1 - 1e-05 25.2 2.5 1.6e-05 24.6 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGB13008.1 - 0.00041 20.3 1.1 0.00076 19.4 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EGB13008.1 - 0.0096 15.6 2.1 0.019 14.7 2.1 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Sel1 PF08238.12 EGB13009.1 - 7.6e-46 153.5 46.6 1.3e-08 35.2 0.4 10.6 10 1 0 10 10 10 9 Sel1 repeat TPR_12 PF13424.6 EGB13009.1 - 0.00042 20.5 27.9 0.55 10.6 1.0 6.4 5 1 2 7 7 7 4 Tetratricopeptide repeat MIT PF04212.18 EGB13009.1 - 0.0017 18.4 22.9 0.022 14.8 1.3 5.4 5 1 1 6 6 6 2 MIT (microtubule interacting and transport) domain B12-binding_2 PF02607.17 EGB13009.1 - 0.4 11.1 4.6 11 6.6 0.2 3.8 3 1 1 4 4 4 0 B12 binding domain TPR_6 PF13174.6 EGB13009.1 - 1.2 9.9 0.0 1.2 9.9 0.0 6.5 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB13009.1 - 3 7.8 27.1 0.96 9.4 0.8 6.7 9 0 0 9 9 9 0 Tetratricopeptide repeat FumaraseC_C PF10415.9 EGB13009.1 - 3.4 8.1 6.5 29 5.2 0.1 3.8 4 0 0 4 4 4 0 Fumarase C C-terminus zf-C3HC4_3 PF13920.6 EGB13010.1 - 0.0047 16.8 14.7 0.0075 16.1 14.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGB13010.1 - 0.014 15.7 17.7 0.025 14.9 17.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGB13010.1 - 0.032 14.1 17.8 0.066 13.1 17.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF5571 PF17732.1 EGB13010.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5571) zf-RING_6 PF14835.6 EGB13010.1 - 0.41 10.5 8.5 0.92 9.4 8.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 EGB13010.1 - 0.51 10.3 17.9 0.84 9.6 17.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB13010.1 - 1.7 8.7 17.1 2.1 8.4 16.4 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGB13010.1 - 2.5 8.2 15.4 4.9 7.3 15.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGB13010.1 - 4.5 7.5 19.8 7.9 6.7 19.8 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Enolase_C PF00113.22 EGB13011.1 - 3.2e-124 414.0 0.0 4.3e-124 413.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGB13011.1 - 3.1e-53 179.4 0.1 5.6e-53 178.6 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGB13011.1 - 1.5e-08 34.5 0.0 2.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGB13011.1 - 4.1e-06 26.1 1.6 5.2e-06 25.8 0.2 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus His_Phos_1 PF00300.22 EGB13012.1 - 5.6e-36 124.1 0.0 3.4e-27 95.4 0.2 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Filamin PF00630.19 EGB13013.1 - 2.1e-25 89.5 0.0 2.4e-13 50.8 0.0 3.2 3 0 0 3 3 3 3 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EGB13013.1 - 0.0037 17.5 0.0 0.21 11.9 0.0 2.3 2 0 0 2 2 2 1 Invasin, domain 3 Ig_2 PF13895.6 EGB13013.1 - 0.15 12.4 0.0 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain GOLD_2 PF13897.6 EGB13014.1 - 3.2e-07 30.9 0.0 0.16 12.4 0.0 3.3 3 0 0 3 3 3 3 Golgi-dynamics membrane-trafficking TUDOR_5 PF18359.1 EGB13014.1 - 6.2e-05 22.6 0.6 0.00015 21.4 0.6 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 EGB13014.1 - 0.002 18.5 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 Agenet domain Tudor_3 PF18115.1 EGB13014.1 - 0.004 17.0 0.1 0.017 14.9 0.1 2.1 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 EGB13014.1 - 0.071 12.9 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF2587 PF10759.9 EGB13014.1 - 6 6.4 5.5 27 4.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) Sel1 PF08238.12 EGB13015.1 - 5.8e-06 26.8 3.6 3.5 8.5 0.1 4.8 4 0 0 4 4 4 2 Sel1 repeat 2OG-FeII_Oxy_3 PF13640.6 EGB13015.1 - 8.6e-06 26.6 0.1 1.6e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_7 PF13176.6 EGB13015.1 - 5.4e-05 22.9 2.2 0.039 14.0 0.2 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGB13015.1 - 0.0019 18.2 5.6 0.11 12.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGB13015.1 - 0.0081 16.3 0.1 8.9 6.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB13015.1 - 0.011 16.0 12.6 0.14 12.5 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGB13015.1 - 0.04 13.8 1.1 1.1 9.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGB13015.1 - 0.048 13.4 0.5 0.8 9.4 0.1 2.8 2 1 0 2 2 2 0 TPR repeat TPR_4 PF07721.14 EGB13015.1 - 0.12 13.1 0.1 0.12 13.1 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGB13015.1 - 6.9 7.3 9.5 0.49 10.9 1.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EGB13016.1 - 7.6e-61 205.8 0.0 1.2e-60 205.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EGB13016.1 - 5e-35 119.5 0.2 1.1e-16 60.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGB13016.1 - 1e-30 106.9 0.0 1.5e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGB13016.1 - 0.03 13.4 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Methyltransf_25 PF13649.6 EGB13017.1 - 2.3e-08 34.6 3.1 2.6e-08 34.4 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGB13017.1 - 8.8e-08 32.7 0.2 1.4e-05 25.7 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGB13017.1 - 2.1e-07 30.9 0.0 1.3e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGB13017.1 - 6.5e-05 23.6 0.0 0.0013 19.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGB13017.1 - 0.00086 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGB13017.1 - 0.0021 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Pkinase PF00069.25 EGB13018.1 - 4.1e-43 147.7 0.0 4.9e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB13018.1 - 2.6e-16 59.7 0.0 5.8e-16 58.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB13018.1 - 0.019 14.9 0.2 0.056 13.4 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGB13018.1 - 0.024 13.4 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGB13018.1 - 0.041 13.2 0.1 0.08 12.3 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 EGB13019.1 - 3.4e-10 40.2 1.2 0.0012 19.2 0.3 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB13019.1 - 1.3e-09 37.2 0.0 0.25 11.4 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EGB13019.1 - 5e-09 35.1 0.1 0.0013 18.1 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EGB13019.1 - 0.00017 21.3 0.3 1.6 8.7 0.0 3.6 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB13019.1 - 0.0012 18.3 0.2 0.14 11.8 0.0 3.4 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 EGB13019.1 - 0.027 14.8 0.7 3 8.2 0.2 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGB13019.1 - 0.06 13.3 0.2 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Phage_clamp_A PF16790.5 EGB13019.1 - 0.11 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit ABC1 PF03109.16 EGB13020.1 - 1e-24 87.0 0.0 1.4e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 ABC1 family WD40 PF00400.32 EGB13021.1 - 9e-41 137.1 18.5 2.2e-07 31.4 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB13021.1 - 6.4e-17 61.6 4.3 0.002 18.4 0.2 6.1 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGB13021.1 - 0.0016 17.4 0.8 0.94 8.4 0.0 3.9 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGB13021.1 - 0.46 9.1 3.6 1.9 7.0 0.2 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF3450 PF11932.8 EGB13022.1 - 0.0013 18.1 2.4 0.0015 17.9 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-H PF05837.12 EGB13022.1 - 0.0021 18.5 0.6 0.0026 18.1 0.6 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) FlgN PF05130.12 EGB13022.1 - 0.0037 17.8 2.7 0.0046 17.5 2.7 1.2 1 0 0 1 1 1 1 FlgN protein TMF_TATA_bd PF12325.8 EGB13022.1 - 0.0085 16.3 3.0 0.033 14.4 2.8 1.8 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 EGB13022.1 - 0.072 13.3 2.4 0.11 12.7 2.4 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Glypican PF01153.19 EGB13022.1 - 0.073 11.9 0.1 0.085 11.7 0.1 1.0 1 0 0 1 1 1 0 Glypican DUF16 PF01519.16 EGB13022.1 - 0.092 13.2 0.7 0.14 12.7 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 YkyA PF10368.9 EGB13022.1 - 0.093 12.4 0.9 0.1 12.2 0.9 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein ABC_tran_CTD PF16326.5 EGB13022.1 - 0.14 12.4 6.3 1.3 9.3 2.1 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 EGB13022.1 - 0.17 12.3 0.3 0.33 11.4 0.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 EGB13022.1 - 0.19 11.8 2.7 0.42 10.7 2.0 1.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF3138 PF11336.8 EGB13022.1 - 0.31 9.6 4.1 0.34 9.5 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) REJ PF02010.15 EGB13023.1 - 1.6e-23 83.2 0.0 2.3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 REJ domain GPS PF01825.21 EGB13023.1 - 0.089 13.3 0.9 0.16 12.5 0.9 1.4 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif Peptidase_M14 PF00246.24 EGB13024.1 - 1.2e-14 54.8 0.0 6e-14 52.5 0.0 2.0 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EGB13024.1 - 6.6e-05 23.2 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EGB13024.1 - 0.00032 19.9 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family SNAP PF14938.6 EGB13027.1 - 3.2e-88 295.8 12.3 3.7e-88 295.6 12.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 EGB13027.1 - 0.75 10.8 4.8 11 7.2 0.0 4.3 3 1 0 4 4 4 0 Tetratricopeptide repeat Sulfotransfer_3 PF13469.6 EGB13028.1 - 0.027 14.9 0.3 5.7 7.2 0.0 2.6 2 1 1 3 3 3 0 Sulfotransferase family DEAD PF00270.29 EGB13030.1 - 3.1e-17 62.9 0.0 5.9e-17 62.0 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGB13030.1 - 2.6e-05 24.3 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGB13030.1 - 4.2e-05 23.9 0.0 8.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGB13030.1 - 0.0032 17.8 0.0 0.026 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain ISN1 PF06437.11 EGB13031.1 - 8.7e-97 324.6 0.0 1.5e-94 317.2 0.0 2.0 1 1 0 1 1 1 1 IMP-specific 5'-nucleotidase Cornifin PF02389.15 EGB13032.1 - 0.019 15.2 0.0 0.019 15.2 0.0 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF2917 PF11142.8 EGB13032.1 - 0.043 13.2 7.6 5.6 6.4 2.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2917) CRA_rpt PF07046.11 EGB13032.1 - 1.6 8.9 18.0 8.2 6.7 8.7 2.8 1 1 1 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat RRM_1 PF00076.22 EGB13033.1 - 6.4e-13 48.3 0.0 6.8e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGB13033.1 - 0.018 15.1 0.0 0.027 14.6 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 EGB13034.1 - 4.6e-18 64.8 0.0 4.9e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGB13034.1 - 0.018 15.1 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GST_C_3 PF14497.6 EGB13035.1 - 2e-08 34.3 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGB13035.1 - 3.2e-07 30.3 0.1 5.7e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGB13035.1 - 1.3e-06 28.7 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGB13035.1 - 0.00018 21.7 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGB13035.1 - 0.0013 19.1 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AMP-binding PF00501.28 EGB13036.1 - 8.1e-61 205.9 0.9 1e-39 136.3 0.1 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EGB13036.1 - 8.4e-18 65.1 0.1 8.4e-18 65.1 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Asp_Arg_Hydrox PF05118.15 EGB13038.1 - 4.8e-23 81.7 0.0 7.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_9 PF13371.6 EGB13038.1 - 5.4e-05 23.3 3.9 0.0023 18.0 3.9 3.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGB13038.1 - 0.00056 20.5 6.0 0.00056 20.5 6.0 7.5 7 2 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGB13038.1 - 5.5 7.4 14.8 0.95 9.7 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 EGB13039.1 - 7.4e-24 84.8 5.7 2.5e-10 40.2 1.0 3.9 2 2 1 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGB13039.1 - 9.4e-15 54.6 0.2 2.2e-14 53.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGB13039.1 - 2.1e-08 34.2 11.0 0.00025 20.8 1.8 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGB13039.1 - 4.6e-07 29.3 5.2 8.7e-05 21.8 2.7 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EGB13039.1 - 5.8e-07 29.0 0.4 0.00019 20.8 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGB13039.1 - 7.6e-06 24.9 0.3 0.099 11.3 0.6 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EGB13039.1 - 3e-05 24.5 0.8 0.0019 18.7 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGB13039.1 - 0.00045 19.7 2.2 0.00059 19.3 1.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGB13039.1 - 0.0016 17.7 0.6 0.0024 17.2 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.18 EGB13039.1 - 0.0017 17.0 0.0 0.12 10.9 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor Thi4 PF01946.17 EGB13039.1 - 0.003 16.8 0.1 0.0054 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family MelC1 PF06236.11 EGB13039.1 - 0.02 15.0 0.4 0.058 13.5 0.4 1.8 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Lycopene_cycl PF05834.12 EGB13039.1 - 0.22 10.5 2.9 5.6 5.9 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EGB13039.1 - 0.69 8.9 3.2 1.4 8.0 0.9 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Nucleotid_trans PF03407.16 EGB13040.1 - 1.1e-21 77.8 0.0 1.6e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-C3HC4_3 PF13920.6 EGB13040.1 - 0.012 15.4 3.8 0.027 14.3 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGB13040.1 - 0.019 14.8 3.2 0.039 13.8 3.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGB13040.1 - 0.45 10.5 4.4 0.93 9.5 4.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 EGB13040.1 - 1.2 9.4 5.0 3.7 7.9 5.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGB13040.1 - 1.7 9.0 11.1 0.25 11.7 5.8 2.2 2 0 0 2 2 2 0 Ring finger domain Acetyltransf_1 PF00583.25 EGB13041.1 - 2.2e-08 34.3 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGB13041.1 - 2e-05 24.5 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGB13041.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGB13041.1 - 0.0016 18.8 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EF-hand_8 PF13833.6 EGB13042.1 - 2.1e-05 24.3 0.2 4e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGB13042.1 - 0.0084 15.6 0.1 0.024 14.2 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EGB13042.1 - 0.036 13.6 0.3 0.075 12.6 0.3 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EGB13042.1 - 0.097 13.1 0.4 0.77 10.3 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair PhoU PF01895.19 EGB13042.1 - 0.29 11.6 2.7 8.4 6.9 0.1 2.9 2 0 0 2 2 2 0 PhoU domain LMF1 PF06762.14 EGB13043.1 - 3.6e-77 260.4 5.9 3.6e-38 131.8 2.8 2.7 1 1 1 2 2 2 2 Lipase maturation factor Tubulin PF00091.25 EGB13044.1 - 3.6e-63 213.3 0.0 5e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGB13044.1 - 2.4e-49 166.7 0.0 3.5e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain U3snoRNP10 PF12397.8 EGB13046.1 - 0.1 12.9 1.0 0.37 11.2 0.1 2.3 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 DUF1459 PF07312.11 EGB13046.1 - 6 7.2 6.4 7.2 6.9 1.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) Ribosomal_S4e PF00900.20 EGB13047.1 - 1.8e-31 107.9 0.1 4.2e-31 106.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGB13047.1 - 1.4e-22 79.0 0.2 2.9e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGB13047.1 - 4.3e-20 71.5 6.1 1.2e-19 70.1 6.1 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EGB13047.1 - 5.6e-11 42.0 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EGB13047.1 - 0.00013 21.8 0.8 0.00013 21.8 0.8 2.5 3 0 0 3 3 3 1 KOW motif S4_2 PF13275.6 EGB13047.1 - 0.097 12.5 0.0 0.39 10.6 0.0 2.0 1 0 0 1 1 1 0 S4 domain Patatin PF01734.22 EGB13048.1 - 5.1e-25 88.9 1.6 1.3e-24 87.5 1.6 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2559 PF10832.8 EGB13048.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) EF-hand_7 PF13499.6 EGB13049.1 - 7.9e-05 23.0 2.7 0.021 15.3 1.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGB13049.1 - 0.034 13.7 0.0 4.4 7.1 0.0 2.7 2 0 0 2 2 2 0 EF hand adh_short PF00106.25 EGB13050.1 - 1.7e-29 102.7 0.0 2.6e-27 95.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGB13050.1 - 1.9e-16 60.4 0.6 5.9e-16 58.7 0.7 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGB13050.1 - 2.4e-07 30.9 0.3 4.2e-07 30.0 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGB13050.1 - 2.6e-05 23.8 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGB13050.1 - 0.044 13.2 0.0 0.088 12.2 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGB13050.1 - 0.087 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Adaptin_N PF01602.20 EGB13051.1 - 8.7e-146 486.5 11.0 1.1e-145 486.2 11.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGB13051.1 - 1.8e-63 213.4 6.7 6.5e-63 211.6 0.7 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGB13051.1 - 1.7e-16 60.3 11.8 4.8e-07 30.1 0.6 5.5 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 EGB13051.1 - 9.4e-10 37.9 4.2 0.037 14.3 0.1 5.4 4 0 0 4 4 4 3 HEAT repeat Arm PF00514.23 EGB13051.1 - 2.1e-05 24.4 2.3 0.0021 18.0 0.0 4.1 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 EGB13051.1 - 2.8e-05 24.1 0.1 0.00027 20.9 0.0 2.6 1 1 1 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cnd3 PF12719.7 EGB13051.1 - 3.1e-05 23.3 0.8 0.00059 19.1 0.1 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 EGB13051.1 - 0.00026 21.2 6.3 4.3 7.6 0.5 4.9 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EGB13051.1 - 0.00049 19.7 0.5 2.6 7.5 0.0 3.9 2 1 2 4 4 4 2 CLASP N terminal Arm_2 PF04826.13 EGB13051.1 - 0.0011 18.5 0.4 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 Armadillo-like DUF5578 PF17741.1 EGB13051.1 - 0.015 14.7 2.1 0.34 10.3 0.1 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5578) UNC45-central PF11701.8 EGB13051.1 - 0.019 14.9 0.1 2.7 7.9 0.0 3.3 2 2 1 3 3 3 0 Myosin-binding striated muscle assembly central Dzip-like_N PF13815.6 EGB13051.1 - 0.083 12.9 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal HEAT_EZ PF13513.6 EGB13051.1 - 0.21 12.2 8.8 15 6.3 0.2 5.8 5 1 2 7 7 7 0 HEAT-like repeat Iso_dh PF00180.20 EGB13052.1 - 3.4e-124 414.5 0.0 3.8e-124 414.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TTL PF03133.15 EGB13053.1 - 8.8e-84 281.1 0.0 1.5e-83 280.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Sel1 PF08238.12 EGB13053.1 - 2.4e-19 69.3 10.2 2.7e-06 27.9 0.1 5.1 5 0 0 5 5 5 4 Sel1 repeat zf-MYND PF01753.18 EGB13053.1 - 1.5e-08 34.6 11.9 1.5e-08 34.6 11.9 2.7 2 0 0 2 2 2 1 MYND finger ATPgrasp_YheCD PF14398.6 EGB13053.1 - 1.7e-07 30.8 0.0 0.0021 17.3 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGB13053.1 - 0.00094 18.5 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp zf-RING_2 PF13639.6 EGB13053.1 - 0.0059 16.9 15.2 0.0059 16.9 15.2 2.5 2 0 0 2 2 2 1 Ring finger domain TPR_12 PF13424.6 EGB13053.1 - 5.4 7.4 7.7 1.8 8.9 1.3 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 EGB13054.1 - 2.4e-67 227.3 29.5 1.7e-35 122.8 9.3 2.3 2 0 0 2 2 2 2 Subtilase family Peptidase_S8_N PF16361.5 EGB13054.1 - 9.2e-15 55.4 0.1 4.7e-06 27.1 0.0 3.2 2 1 0 2 2 2 2 N-terminal of Subtilase family PT PF04886.12 EGB13054.1 - 2.5e-13 49.3 79.4 0.0045 16.5 16.1 5.0 2 1 1 3 3 3 2 PT repeat Sec1 PF00995.23 EGB13055.1 - 2.4e-108 363.9 0.0 3.7e-108 363.2 0.0 1.3 1 1 0 1 1 1 1 Sec1 family LCM PF04072.14 EGB13056.1 - 1.5e-32 113.1 0.0 2.9e-32 112.1 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Dynein_light PF01221.18 EGB13057.1 - 2.5e-27 95.0 2.2 2.7e-27 94.9 2.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 SET PF00856.28 EGB13058.1 - 1.5e-23 84.1 0.0 1.1e-22 81.2 0.0 2.1 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 EGB13058.1 - 2.1e-16 60.5 3.3 2.1e-16 60.5 3.3 2.6 3 0 0 3 3 3 1 Pre-SET motif PHD PF00628.29 EGB13058.1 - 0.00013 21.8 4.2 0.00013 21.8 4.2 3.3 3 0 0 3 3 3 1 PHD-finger Ribosomal_S28e PF01200.18 EGB13061.1 - 3.8e-32 110.1 0.2 4.1e-32 110.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DUF3850 PF12961.7 EGB13061.1 - 0.11 12.6 0.0 2 8.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3850) PT PF04886.12 EGB13062.1 - 3.6e-36 122.4 422.9 7.5e-07 28.6 19.9 19.7 8 6 9 17 17 17 15 PT repeat Peptidase_S8 PF00082.22 EGB13062.1 - 2.3e-19 69.8 14.1 4.3e-17 62.3 10.0 2.5 1 1 1 2 2 2 2 Subtilase family Peptidase_S8_N PF16361.5 EGB13062.1 - 9.8e-06 26.1 0.0 7.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal of Subtilase family AMP-binding PF00501.28 EGB13063.1 - 1.7e-64 218.0 0.0 2.3e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGB13063.1 - 1.3e-07 31.8 0.0 5.9e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGB13063.1 - 0.2 12.7 0.3 0.72 10.9 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Nuc_sug_transp PF04142.15 EGB13064.1 - 2.9e-90 302.6 2.2 3.3e-90 302.4 2.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB13064.1 - 1.7e-05 25.0 1.6 1.7e-05 25.0 1.6 2.8 2 1 0 2 2 2 1 EamA-like transporter family CRT-like PF08627.10 EGB13064.1 - 0.00059 18.9 1.7 0.00093 18.2 0.2 1.8 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 EGB13064.1 - 0.11 11.6 6.1 0.019 14.2 2.3 1.7 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Phage_holin_2_1 PF04971.12 EGB13064.1 - 0.25 11.4 3.3 0.75 9.8 0.1 2.9 2 1 1 3 3 3 0 Bacteriophage P21 holin S PPTA PF01239.22 EGB13065.1 - 2.5e-27 93.7 6.2 5.2e-08 32.4 0.5 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat ABC1 PF03109.16 EGB13066.1 - 7.1e-20 71.4 0.0 1.8e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EGB13066.1 - 2.3e-05 24.5 2.7 0.00075 19.5 2.7 3.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family TRAM_LAG1_CLN8 PF03798.16 EGB13067.1 - 5e-14 52.5 7.9 7.7e-14 51.9 7.9 1.3 1 0 0 1 1 1 1 TLC domain p450 PF00067.22 EGB13068.1 - 1.6e-38 132.7 0.0 1.9e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PP2C PF00481.21 EGB13069.1 - 1.3e-35 123.3 0.0 1.9e-34 119.5 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C NAD_binding_11 PF14833.6 EGB13069.1 - 4.3e-32 110.9 0.2 4.3e-32 110.9 0.2 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EGB13069.1 - 8.6e-27 94.2 6.4 1.6e-26 93.4 6.4 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGB13069.1 - 2.6e-06 27.9 0.8 8e-06 26.4 0.8 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGB13069.1 - 0.00074 18.9 0.0 0.0059 16.0 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PP2C_2 PF13672.6 EGB13069.1 - 0.0054 16.4 2.2 0.0054 16.4 2.2 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C GFO_IDH_MocA PF01408.22 EGB13069.1 - 0.014 16.2 0.8 0.41 11.5 0.3 2.8 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold PDH PF02153.17 EGB13069.1 - 0.079 12.0 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase HORMA PF02301.18 EGB13070.1 - 1.4e-22 80.3 0.0 2e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Ala_racemase_N PF01168.20 EGB13070.1 - 0.029 14.0 0.0 0.084 12.5 0.0 1.7 1 1 0 1 1 1 0 Alanine racemase, N-terminal domain bacHORMA_2 PF18173.1 EGB13070.1 - 0.051 13.4 0.2 0.28 11.0 0.0 2.0 1 1 0 2 2 2 0 Bacterial HORMA domain 2 Hpr_kinase_N PF02603.16 EGB13070.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase N terminus Potex_coat PF06184.11 EGB13070.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein PH PF00169.29 EGB13071.1 - 0.014 15.9 0.1 0.03 14.8 0.1 1.5 1 0 0 1 1 1 0 PH domain NB-ARC PF00931.22 EGB13072.1 - 1.2e-09 37.7 0.0 2.7e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain WD40 PF00400.32 EGB13072.1 - 0.00034 21.4 13.1 8 7.5 0.0 8.6 9 1 0 9 9 9 2 WD domain, G-beta repeat Mcl1_mid PF12341.8 EGB13072.1 - 0.018 14.4 0.0 2.5 7.4 0.0 2.6 3 0 0 3 3 3 0 Minichromosome loss protein, Mcl1, middle region CysA_C_terminal PF17850.1 EGB13072.1 - 1.8 9.2 7.0 6.7 7.4 1.0 3.9 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Chloroa_b-bind PF00504.21 EGB13073.1 - 6e-33 114.7 0.4 7.7e-33 114.3 0.4 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TCR PF03638.15 EGB13074.1 - 9.1e-23 80.3 60.5 2.3e-12 47.0 20.0 3.1 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Lung_7-TM_R PF06814.13 EGB13075.1 - 1.9e-47 162.0 11.8 2.1e-47 161.8 11.8 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EGB13075.1 - 0.00061 19.3 10.8 0.00093 18.7 10.8 1.3 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain PUF PF00806.19 EGB13077.1 - 5.7e-54 176.9 0.0 2.4e-07 30.1 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EGB13077.1 - 0.011 16.1 0.0 5.8 7.3 0.0 3.2 2 1 1 3 3 3 0 CPL (NUC119) domain hnRNP_Q_AcD PF18360.1 EGB13077.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Iso_dh PF00180.20 EGB13077.1 - 0.19 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase DUF3636 PF12331.8 EGB13078.1 - 0.07 13.0 1.1 2.1 8.2 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3636) DnaJ PF00226.31 EGB13079.1 - 5.5e-25 87.3 0.8 6.3e-25 87.1 0.8 1.0 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGB13079.1 - 0.094 12.7 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 A repeated domain in UCH-protein NTP_transferase PF00483.23 EGB13080.1 - 5.1e-05 23.0 0.0 6.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Methyltransf_16 PF10294.9 EGB13081.1 - 4.6e-19 68.8 0.0 8.1e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase TetR_C_28 PF17937.1 EGB13081.1 - 0.0034 17.8 1.3 0.013 15.9 1.3 2.0 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF4476 PF14771.6 EGB13081.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Cu_bind_like PF02298.17 EGB13082.1 - 0.0029 17.6 0.2 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 Plastocyanin-like domain HIT PF01230.23 EGB13083.1 - 2.9e-28 98.5 0.0 3.3e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGB13083.1 - 8e-18 65.0 0.0 9.4e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding C2 PF00168.30 EGB13084.1 - 2.5e-65 217.2 0.0 7.2e-18 64.8 0.0 6.8 6 1 0 6 6 6 5 C2 domain FMO-like PF00743.19 EGB13085.1 - 8.7e-28 97.0 0.6 1.2e-27 96.5 0.6 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGB13085.1 - 9.1e-11 41.6 0.1 6.2e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGB13085.1 - 1.9e-10 40.5 0.1 2.5e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGB13085.1 - 5e-10 39.1 0.5 1.4e-09 37.5 0.1 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGB13085.1 - 9.2e-07 29.0 0.6 4e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGB13085.1 - 0.037 13.1 0.1 6.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGB13085.1 - 0.053 14.1 2.3 10 6.8 0.2 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGB13085.1 - 0.062 12.6 0.0 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mqo PF06039.15 EGB13085.1 - 0.079 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Nbas_N PF15492.6 EGB13085.1 - 0.087 12.1 0.3 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Shikimate_DH PF01488.20 EGB13085.1 - 0.12 12.4 0.1 24 5.0 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EGB13085.1 - 0.18 11.0 0.3 14 4.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EGB13085.1 - 0.19 10.4 1.0 0.71 8.5 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein GlcNAc_2-epim PF07221.11 EGB13086.1 - 3.1e-25 89.2 0.2 4.4e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DBR1 PF05011.13 EGB13086.1 - 1.9e-19 70.5 0.0 3.2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EGB13086.1 - 1.8e-07 31.9 0.3 5.3e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGB13086.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain T7SS_ESX_EspC PF10824.8 EGB13087.1 - 2.5 8.6 17.4 0.16 12.4 9.7 3.3 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm CENP-T_C PF15511.6 EGB13088.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB13088.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB13088.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB13088.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB13088.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB13088.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB13088.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGB13088.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 EGB13089.1 - 5.4e-19 68.8 0.4 6.5e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGB13089.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGB13089.1 - 0.0039 17.7 0.0 0.0061 17.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGB13089.1 - 0.054 13.5 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein Myosin_head PF00063.21 EGB13090.1 - 1.2e-206 688.0 0.0 1.5e-206 687.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 EGB13090.1 - 0.0013 19.0 0.0 0.0073 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGB13090.1 - 0.01 16.2 0.3 0.22 11.9 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 EGB13090.1 - 0.064 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 EGB13090.1 - 0.19 11.7 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 EGB13090.1 - 0.2 10.6 0.1 0.75 8.6 0.0 2.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Ephrin_rec_like PF07699.13 EGB13091.1 - 1.8e-41 139.7 103.8 1.1e-07 31.5 5.9 10.5 6 3 4 11 11 11 10 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGB13091.1 - 1.9e-07 31.4 56.1 0.28 11.6 0.4 11.4 5 4 6 11 11 11 8 TNFR/NGFR cysteine-rich region VSP PF03302.13 EGB13091.1 - 0.042 12.7 107.2 0.54 9.0 8.5 5.0 1 1 4 5 5 5 0 Giardia variant-specific surface protein G6PD_C PF02781.16 EGB13092.1 - 2.3e-91 306.0 0.0 3.2e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGB13092.1 - 2e-44 152.3 0.0 2.9e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain EF-hand_7 PF13499.6 EGB13092.1 - 6.6e-07 29.7 1.9 3.1e-05 24.4 0.8 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGB13092.1 - 7.8e-05 22.3 0.4 0.00038 20.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGB13092.1 - 0.00019 20.7 0.4 0.011 15.2 0.0 3.2 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 EGB13092.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.9 EGB13092.1 - 0.043 14.1 0.1 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EGB13092.1 - 0.21 11.5 0.5 0.75 9.7 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair Spermine_synth PF01564.17 EGB13093.1 - 1.5e-09 37.5 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain zf-MYND PF01753.18 EGB13093.1 - 5.3e-08 32.8 9.3 1.1e-07 31.8 9.3 1.5 1 0 0 1 1 1 1 MYND finger Glyco_tranf_2_4 PF13704.6 EGB13093.1 - 2.7e-05 24.6 0.1 7.8e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Rotamase_3 PF13616.6 EGB13093.1 - 7.2e-05 23.3 0.0 0.0002 21.9 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EGB13093.1 - 0.00014 22.8 0.1 0.00067 20.6 0.0 2.2 2 0 0 2 2 2 1 PPIC-type PPIASE domain Spermine_synt_N PF17284.2 EGB13093.1 - 0.022 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain zf-C6H2 PF15801.5 EGB13093.1 - 7.6 6.9 7.8 14 6.1 7.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding GST_N_3 PF13417.6 EGB13094.1 - 7.1e-20 71.2 0.0 9e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGB13094.1 - 1.9e-16 60.1 0.0 2.3e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGB13094.1 - 5e-11 42.8 0.0 6.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EGB13094.1 - 0.16 12.7 0.0 0.21 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Sulfotransfer_1 PF00685.27 EGB13095.1 - 1.3e-29 103.5 0.0 1.5e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGB13095.1 - 3.4e-07 30.9 0.2 0.00043 20.7 0.1 2.1 1 1 1 2 2 2 2 Sulfotransferase family zf_Hakai PF18408.1 EGB13095.1 - 0.054 13.2 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain GP68 PF17469.2 EGB13095.1 - 0.21 12.0 0.6 15 6.1 0.6 2.8 1 1 0 1 1 1 0 Phage protein Gp68 Peptidase_C1 PF00112.23 EGB13096.1 - 4.5e-43 147.9 7.6 8.9e-43 146.9 7.6 1.4 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGB13096.1 - 0.023 13.5 0.8 3.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family TPR_2 PF07719.17 EGB13097.1 - 7.8e-11 41.2 7.0 0.029 14.5 0.2 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGB13097.1 - 8e-09 35.0 2.1 0.11 12.4 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGB13097.1 - 1.2e-08 35.1 12.5 0.00035 20.8 0.3 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGB13097.1 - 2.3e-07 30.5 0.0 0.29 11.5 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGB13097.1 - 8.6e-07 28.5 0.5 0.045 13.4 0.0 4.5 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.6 EGB13097.1 - 3.3e-05 23.6 0.1 0.66 10.1 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGB13097.1 - 5.8e-05 22.4 4.0 0.0074 15.5 1.1 3.0 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGB13097.1 - 8.6e-05 23.0 35.2 0.016 16.0 1.2 7.3 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGB13097.1 - 9.9e-05 22.9 4.5 9.9e-05 22.9 4.5 6.6 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGB13097.1 - 0.00024 21.2 3.9 17 6.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB13097.1 - 0.0011 18.8 13.6 0.7 9.8 0.5 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGB13097.1 - 0.0051 17.3 17.6 0.029 14.9 0.3 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 EGB13097.1 - 0.0085 16.5 7.8 0.0085 16.5 7.8 4.0 2 2 2 4 4 4 1 Bacterial transcriptional activator domain Coatomer_E PF04733.14 EGB13097.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit DUF3245 PF11595.8 EGB13097.1 - 0.33 11.4 1.9 0.62 10.5 1.6 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3245) TPR_9 PF13371.6 EGB13097.1 - 2.5 8.3 22.4 11 6.3 2.7 4.6 3 1 0 4 4 4 0 Tetratricopeptide repeat ArfGap PF01412.18 EGB13098.1 - 1.3e-16 60.7 0.3 1.7e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CxC3 PF18804.1 EGB13098.1 - 0.012 15.5 0.7 0.018 14.8 0.7 1.2 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases ADH_N PF08240.12 EGB13098.1 - 0.42 10.5 3.1 0.7 9.8 3.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain FSH1 PF03959.13 EGB13099.1 - 2.2e-44 151.7 0.0 2.9e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EGB13099.1 - 5.3e-06 26.4 0.0 9.7e-06 25.5 0.0 1.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 EGB13099.1 - 0.0022 17.7 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Sulfate_transp PF00916.20 EGB13101.1 - 7e-45 153.4 17.2 3e-44 151.3 17.2 1.9 1 1 0 1 1 1 1 Sulfate permease family DUF2269 PF10027.9 EGB13101.1 - 0.003 17.6 0.5 0.003 17.6 0.5 2.1 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2269) HCO3_cotransp PF00955.21 EGB13101.1 - 0.42 9.4 8.0 2.8 6.7 2.2 2.6 2 1 0 2 2 2 0 HCO3- transporter family Peptidase_S9 PF00326.21 EGB13102.1 - 1.7e-57 194.3 0.6 3.4e-57 193.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 EGB13102.1 - 1e-51 175.8 0.0 6.4e-51 173.2 0.0 1.9 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 EGB13102.1 - 3.2e-14 53.2 0.9 5.1e-12 45.9 0.8 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EGB13102.1 - 4.7e-07 29.6 0.1 1.2e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EGB13102.1 - 9.9e-06 25.0 0.4 0.001 18.4 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGB13102.1 - 9.4e-05 22.2 0.7 0.00047 19.9 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 EGB13102.1 - 0.018 13.7 0.0 0.029 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 EGB13102.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) BAAT_C PF08840.11 EGB13102.1 - 0.058 13.3 0.0 3.1 7.7 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3141 PF11339.8 EGB13102.1 - 0.08 11.4 0.3 0.12 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) PD40 PF07676.12 EGB13102.1 - 0.11 12.5 0.1 32 4.6 0.0 3.1 4 0 0 4 4 3 0 WD40-like Beta Propeller Repeat Esterase PF00756.20 EGB13102.1 - 0.17 11.5 0.3 0.38 10.4 0.3 1.5 1 0 0 1 1 1 0 Putative esterase PQQ PF01011.21 EGB13102.1 - 0.3 11.1 1.5 15 5.7 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PMSR PF01625.21 EGB13103.1 - 8.3e-51 172.2 0.7 1.1e-50 171.8 0.7 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 EGB13103.1 - 0.097 12.5 0.3 0.52 10.2 0.1 2.2 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr DnaJ PF00226.31 EGB13105.1 - 2.6e-17 62.7 0.0 4.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 EGB13105.1 - 3.1e-16 59.2 0.0 4.8e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin SNF5 PF04855.12 EGB13105.1 - 3.5e-14 53.2 0.0 5.4e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 Thioredoxin_8 PF13905.6 EGB13105.1 - 0.19 12.0 0.0 1.2 9.6 0.0 2.2 2 1 1 3 3 3 0 Thioredoxin-like Ammonium_transp PF00909.21 EGB13106.1 - 2.4e-115 385.5 30.8 2.7e-115 385.3 30.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3188 PF11384.8 EGB13106.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Sel1 PF08238.12 EGB13108.1 - 8.7e-19 67.6 7.1 1.2e-08 35.3 0.0 3.4 3 1 0 3 3 3 3 Sel1 repeat TPR_12 PF13424.6 EGB13108.1 - 0.055 13.8 4.7 2.9 8.3 4.7 3.2 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGB13108.1 - 1.6 9.4 12.0 0.59 10.8 4.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB13108.1 - 9 6.3 12.1 1.8 8.5 0.6 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat APS_kinase PF01583.20 EGB13109.1 - 9e-57 191.4 0.0 1.1e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EGB13109.1 - 0.001 19.3 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGB13109.1 - 0.0022 17.7 0.1 0.0049 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGB13109.1 - 0.0029 18.2 0.0 0.0043 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGB13109.1 - 0.0071 16.9 0.1 0.012 16.1 0.0 1.4 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 EGB13109.1 - 0.0098 15.2 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 EGB13109.1 - 0.026 14.6 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 EGB13109.1 - 0.064 12.9 0.1 0.097 12.3 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KTI12 PF08433.10 EGB13109.1 - 0.26 10.7 0.0 0.37 10.2 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_pol_Rpb1_5 PF04998.17 EGB13110.1 - 1.3e-88 296.9 0.0 1.8e-88 296.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EGB13110.1 - 1.5e-74 251.1 0.0 2.2e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EGB13110.1 - 2.4e-71 239.3 0.0 4.6e-71 238.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGB13110.1 - 4.1e-39 134.0 0.0 7.6e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGB13110.1 - 1.2e-26 92.8 0.0 2.1e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 tRNA-synt_1 PF00133.22 EGB13111.1 - 1.7e-32 112.5 0.0 1.6e-12 46.5 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGB13111.1 - 5.3e-21 74.8 0.0 1e-10 40.9 0.0 3.0 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGB13111.1 - 7.1e-07 28.9 0.0 2.9e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGB13111.1 - 0.06 12.3 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Mito_carr PF00153.27 EGB13112.1 - 1.5e-53 178.6 0.5 6.9e-21 74.0 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein AAA_2 PF07724.14 EGB13114.1 - 2.2e-52 177.7 0.0 1.4e-49 168.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGB13114.1 - 1.3e-25 89.3 0.1 2.6e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 EGB13114.1 - 2.5e-24 86.2 0.1 6.8e-13 49.2 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGB13114.1 - 3.5e-19 69.2 0.0 2.1e-11 44.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 EGB13114.1 - 3.7e-18 65.4 0.2 1.1e-17 63.8 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EGB13114.1 - 1.6e-15 56.9 7.0 1.2e-09 38.1 1.1 3.4 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 EGB13114.1 - 1.5e-09 37.8 0.1 5.9e-07 29.3 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGB13114.1 - 2.3e-08 34.6 11.0 0.0049 17.3 0.1 5.3 6 1 1 7 7 5 2 AAA ATPase domain Torsin PF06309.11 EGB13114.1 - 1.3e-07 31.8 0.0 3.3e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Torsin AAA_22 PF13401.6 EGB13114.1 - 3.2e-07 30.7 0.9 0.014 15.7 0.0 4.0 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 EGB13114.1 - 3.3e-07 30.2 0.1 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EGB13114.1 - 4.5e-07 30.0 0.0 0.001 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EGB13114.1 - 9.3e-06 25.5 0.0 0.58 9.9 0.0 4.1 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EGB13114.1 - 1.1e-05 25.1 0.3 0.0063 16.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGB13114.1 - 1.2e-05 25.3 0.0 0.0058 16.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EGB13114.1 - 1.9e-05 25.2 0.1 0.26 11.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EGB13114.1 - 2.3e-05 24.0 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGB13114.1 - 2.5e-05 23.7 0.0 0.018 14.3 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin TniB PF05621.11 EGB13114.1 - 2.5e-05 23.8 0.0 0.31 10.4 0.0 3.6 3 1 1 4 4 4 2 Bacterial TniB protein ResIII PF04851.15 EGB13114.1 - 0.00019 21.5 0.0 0.092 12.7 0.0 3.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EGB13114.1 - 0.0002 21.7 0.0 1.3 9.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EGB13114.1 - 0.00089 19.4 0.0 0.76 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGB13114.1 - 0.00094 18.5 0.2 0.23 10.7 0.0 2.7 2 1 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGB13114.1 - 0.0017 17.8 0.1 2.9 7.2 0.0 3.1 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGB13114.1 - 0.0023 17.9 0.0 2.4 8.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGB13114.1 - 0.0031 17.4 0.0 1 9.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGB13114.1 - 0.0051 16.7 0.0 2.4 8.1 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase Roc PF08477.13 EGB13114.1 - 0.0084 16.3 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EGB13114.1 - 0.0094 16.2 1.0 9.8 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGB13114.1 - 0.011 15.4 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 EGB13114.1 - 0.049 12.5 0.0 0.12 11.3 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase AAA_17 PF13207.6 EGB13114.1 - 0.05 14.0 0.3 9.5 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EGB13114.1 - 0.056 12.6 0.0 4 6.5 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain ABC_tran PF00005.27 EGB13114.1 - 0.068 13.7 0.0 4.8 7.7 0.0 2.6 2 0 0 2 2 2 0 ABC transporter CbiA PF01656.23 EGB13114.1 - 0.13 12.3 0.8 21 5.2 0.0 3.3 4 0 0 4 4 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DNA_pol3_delta2 PF13177.6 EGB13114.1 - 0.18 11.6 0.0 2.7 7.8 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III, delta subunit Amidohydro_2 PF04909.14 EGB13115.1 - 5.7e-23 82.1 1.3 6.6e-23 81.9 1.3 1.0 1 0 0 1 1 1 1 Amidohydrolase UPF0225 PF17775.1 EGB13116.1 - 6.1e-22 78.3 0.0 7.4e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 EGB13116.1 - 4.1e-06 26.6 3.7 7.2e-06 25.8 3.7 1.4 1 0 0 1 1 1 1 SEC-C motif DUF3394 PF11874.8 EGB13116.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Chloroa_b-bind PF00504.21 EGB13117.1 - 1.3e-31 110.3 0.1 1.7e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein 2OG-FeII_Oxy_5 PF13759.6 EGB13118.1 - 3.2e-19 69.2 0.0 7e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase zf-CXXC PF02008.20 EGB13118.1 - 3.9e-11 42.8 16.1 1.2e-10 41.2 16.1 1.9 1 0 0 1 1 1 1 CXXC zinc finger domain APG6_N PF17675.1 EGB13118.1 - 0.00014 22.4 6.2 0.0066 17.0 0.5 2.7 2 0 0 2 2 2 2 Apg6 coiled-coil region HALZ PF02183.18 EGB13118.1 - 0.0035 17.5 3.2 2 8.7 0.1 2.7 2 0 0 2 2 2 2 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 EGB13118.1 - 1.5 8.8 3.6 6.8 6.7 0.7 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FYVE PF01363.21 EGB13120.1 - 1e-12 48.0 2.5 2.3e-12 46.8 2.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Glyco_transf_90 PF05686.12 EGB13120.1 - 1.2e-06 27.7 0.1 4.7e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_transf_92 PF01697.27 EGB13120.1 - 0.06 13.0 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 Tom5 PF10642.9 EGB13120.1 - 1.1 9.3 2.9 21 5.3 0.0 2.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Pkinase PF00069.25 EGB13121.1 - 1.3e-63 214.8 0.0 1.5e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB13121.1 - 3e-29 102.1 0.0 3.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGB13121.1 - 0.0005 19.5 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGB13121.1 - 0.017 14.1 0.2 0.024 13.6 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain EF-hand_1 PF00036.32 EGB13122.1 - 4e-11 41.6 5.5 0.0016 17.8 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGB13122.1 - 1.6e-10 40.0 2.5 0.0011 18.7 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGB13122.1 - 2.1e-10 40.9 9.9 2.1e-05 24.9 0.9 3.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 EGB13122.1 - 7.4e-07 28.9 4.4 0.054 13.3 0.2 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGB13122.1 - 3.2e-05 23.2 4.5 0.0028 17.1 0.0 3.6 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 EGB13122.1 - 0.078 13.3 0.4 5 7.5 0.0 2.5 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 EGB13122.1 - 0.26 11.2 2.5 3.4 7.6 0.1 3.1 2 2 3 5 5 5 0 Tellurite resistance protein TerB Pkinase PF00069.25 EGB13123.1 - 1.1e-57 195.4 0.0 1.3e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB13123.1 - 2.9e-32 112.0 0.0 3.5e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGB13123.1 - 0.00027 20.3 0.2 0.00066 19.1 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGB13123.1 - 0.014 15.3 2.7 0.1 12.5 0.5 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB13123.1 - 0.016 14.5 0.1 0.14 11.4 0.1 2.1 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGB13123.1 - 0.041 12.7 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SRA1 PF07304.11 EGB13123.1 - 0.073 12.9 0.2 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) TMEM107 PF14995.6 EGB13124.1 - 6.7e-36 123.4 0.1 6.7e-36 123.4 0.1 2.1 2 1 0 2 2 2 1 Transmembrane protein Ank_2 PF12796.7 EGB13124.1 - 6.5e-27 94.0 16.2 0.0061 17.1 0.0 11.3 8 4 4 13 13 13 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGB13124.1 - 2e-14 53.4 27.5 0.003 17.9 0.1 12.1 12 2 1 13 13 13 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGB13124.1 - 1.2e-12 48.1 27.3 4.2 8.1 0.1 15.1 13 3 3 16 16 16 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGB13124.1 - 2.5e-12 45.8 34.6 3.7 8.4 0.0 17.3 19 0 0 19 19 19 2 Ankyrin repeat Ank PF00023.30 EGB13124.1 - 5.4e-11 42.4 49.6 0.67 10.5 0.1 14.8 15 1 0 15 15 15 5 Ankyrin repeat DnaJ PF00226.31 EGB13124.1 - 1.5e-06 28.2 0.3 3.8e-06 26.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain LETM1 PF07766.13 EGB13125.1 - 2.3e-21 76.4 0.0 3.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 LETM1-like protein DUF726 PF05277.12 EGB13126.1 - 1.2e-24 86.9 0.0 1.4e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cupin_2 PF07883.11 EGB13128.1 - 0.00023 20.8 0.4 0.046 13.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain IL4_i_Ig PF18258.1 EGB13128.1 - 0.19 12.0 0.1 0.32 11.2 0.1 1.3 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain Mito_carr PF00153.27 EGB13129.1 - 3.6e-27 94.1 2.3 8.6e-09 35.2 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein PNTB PF02233.16 EGB13130.1 - 7.2e-172 572.4 19.7 7.2e-172 572.4 19.7 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EGB13130.1 - 3.5e-66 222.6 5.6 3.5e-66 222.6 5.6 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EGB13130.1 - 8.7e-38 129.7 0.0 1.7e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EGB13130.1 - 4.3e-27 94.4 6.4 4.3e-27 94.4 6.4 3.5 3 0 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Glu_dehyd_C PF16912.5 EGB13130.1 - 0.0014 18.2 0.4 0.81 9.1 0.1 2.6 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus TPP_enzyme_M PF00205.22 EGB13130.1 - 0.0024 17.6 5.5 0.077 12.7 0.2 3.4 3 1 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 EGB13130.1 - 0.015 15.3 6.2 0.22 11.5 6.1 3.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase FUSC-like PF12805.7 EGB13130.1 - 9.3 5.2 5.5 16 4.4 5.5 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Pkinase PF00069.25 EGB13131.1 - 1e-41 143.1 0.0 2.8e-28 99.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGB13131.1 - 3.3e-15 56.1 0.0 6.1e-15 55.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase U-box PF04564.15 EGB13132.1 - 4.1e-11 42.9 0.0 7.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EGB13132.1 - 0.00034 20.7 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EGB13132.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SET PF00856.28 EGB13135.1 - 3.6e-16 60.0 0.0 1.8e-15 57.7 0.0 1.8 1 1 0 1 1 1 1 SET domain Ion_trans PF00520.31 EGB13136.1 - 2.2e-16 59.8 11.1 3.5e-16 59.2 11.1 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGB13136.1 - 8.5e-09 35.3 2.0 8.5e-09 35.3 2.0 2.1 2 0 0 2 2 2 1 Ion channel IRK PF01007.20 EGB13136.1 - 0.034 14.0 0.9 0.08 12.8 0.9 1.6 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain DUF4116 PF13475.6 EGB13136.1 - 0.066 13.0 0.0 0.99 9.2 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) CPL PF08144.11 EGB13137.1 - 3.8e-11 43.5 0.0 1.3e-09 38.5 0.0 3.0 3 0 0 3 3 3 1 CPL (NUC119) domain MFS_1 PF07690.16 EGB13137.1 - 1.9e-09 36.9 44.5 1.9e-09 36.9 44.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SDA1 PF05285.12 EGB13137.1 - 0.0014 18.1 5.2 0.0021 17.5 5.2 1.2 1 0 0 1 1 1 1 SDA1 FDX-ACB PF03147.14 EGB13137.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain 2OG-FeII_Oxy_3 PF13640.6 EGB13138.1 - 3.6e-15 56.6 0.0 7.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_31 PF01055.26 EGB13139.1 - 1.4e-127 426.6 0.6 2e-127 426.0 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGB13139.1 - 3e-16 59.5 0.1 6.2e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EGB13139.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) DUF16 PF01519.16 EGB13139.1 - 3.4 8.2 6.6 2.5 8.6 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 PAE PF03283.13 EGB13140.1 - 1.7e-10 40.6 0.0 2.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Pectinacetylesterase WD40 PF00400.32 EGB13141.1 - 3e-24 84.8 5.0 3.1e-05 24.6 0.5 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGB13141.1 - 6.9e-17 61.5 0.0 2.1e-05 24.8 0.0 5.2 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGB13141.1 - 7.2e-06 25.5 0.0 1.5 8.0 0.0 3.9 4 0 0 4 4 4 3 WD40-like domain PD40 PF07676.12 EGB13141.1 - 0.00019 21.3 0.5 0.6 10.1 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGB13141.1 - 0.00099 18.2 0.0 0.037 13.0 0.0 2.5 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 EGB13141.1 - 0.025 15.0 4.3 8.5 7.0 0.0 4.6 4 1 1 5 5 5 0 PQQ-like domain PQQ PF01011.21 EGB13141.1 - 0.034 14.1 4.6 0.56 10.2 0.3 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat Ricin_B_lectin PF00652.22 EGB13141.1 - 0.15 12.3 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Glyco_trans_1_4 PF13692.6 EGB13142.1 - 1.2e-09 38.7 1.8 1.5e-09 38.4 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGB13142.1 - 4e-09 36.2 0.0 9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGB13142.1 - 8.4e-09 36.1 9.3 8.4e-09 36.1 9.3 4.7 3 2 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EGB13142.1 - 3.9e-07 30.2 0.4 3.9e-07 30.2 0.4 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 EamA PF00892.20 EGB13142.1 - 2.3e-06 27.8 17.9 9.7e-05 22.6 1.2 3.2 3 0 0 3 3 3 2 EamA-like transporter family NAPRTase_N PF17767.1 EGB13143.1 - 2.9e-38 131.1 0.0 5.3e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 EGB13143.1 - 3.4e-28 98.3 0.0 6.1e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 EGB13143.1 - 0.00012 21.7 0.0 0.026 14.1 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family BAG6 PF12057.8 EGB13143.1 - 0.046 13.4 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 BCL2-associated athanogene 6 QRPTase_N PF02749.16 EGB13143.1 - 0.11 12.6 0.0 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain EF-hand_1 PF00036.32 EGB13144.1 - 8.1e-26 87.6 3.7 1.5e-08 33.6 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGB13144.1 - 2.3e-24 85.6 4.8 5.3e-16 58.8 2.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGB13144.1 - 9.8e-22 75.0 4.1 1.2e-06 28.0 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EGB13144.1 - 1.1e-16 60.4 7.0 4.7e-11 42.4 0.4 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EGB13144.1 - 9.5e-15 54.7 0.0 4.2e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGB13144.1 - 9e-14 50.3 9.9 0.00013 21.3 0.9 3.7 3 1 1 4 4 4 3 EF hand EF-hand_4 PF12763.7 EGB13144.1 - 0.00055 19.9 0.5 0.026 14.5 0.2 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EGB13144.1 - 0.00088 19.2 0.0 4.5 7.2 0.0 3.0 2 1 1 3 3 3 2 Caleosin related protein EF-hand_14 PF17959.1 EGB13144.1 - 0.0074 16.6 0.9 1.3 9.4 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain EcoR124_C PF12008.8 EGB13144.1 - 0.019 14.6 1.2 0.022 14.4 1.2 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal TerB PF05099.13 EGB13144.1 - 0.044 13.7 3.1 6.1 6.8 0.2 2.7 1 1 1 3 3 3 0 Tellurite resistance protein TerB SurA_N_2 PF13623.6 EGB13144.1 - 0.059 13.2 1.5 0.34 10.8 0.7 2.1 1 1 1 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 EGB13144.1 - 0.14 12.5 0.6 0.33 11.3 0.3 1.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DED PF01335.21 EGB13144.1 - 0.22 11.9 3.5 6.4 7.2 0.1 2.6 2 1 1 3 3 3 0 Death effector domain EF-hand_10 PF14788.6 EGB13144.1 - 0.4 10.6 3.3 11 6.0 0.0 2.6 2 0 0 2 2 2 0 EF hand SHOCT PF09851.9 EGB13144.1 - 0.41 10.5 0.1 0.41 10.5 0.1 3.9 4 1 0 4 4 4 0 Short C-terminal domain Thioredoxin PF00085.20 EGB13145.1 - 0.001 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ribosomal_L24 PF17136.4 EGB13146.1 - 5.9e-13 49.0 0.0 9.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EGB13146.1 - 9.7e-07 28.5 3.0 2.5e-06 27.2 3.0 1.7 1 0 0 1 1 1 1 KOW motif PBP_like_2 PF12849.7 EGB13147.1 - 1e-37 130.3 0.1 1.3e-37 130.0 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_6 PF13343.6 EGB13147.1 - 0.066 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein UPF0054 PF02130.17 EGB13148.1 - 1.1e-31 109.3 0.0 2.8e-31 108.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein family UPF0054 GCS PF03074.16 EGB13149.1 - 1.5e-144 481.9 0.0 1.9e-144 481.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 EGB13149.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Aminotran_5 PF00266.19 EGB13151.1 - 5.6e-31 107.8 0.0 4.1e-30 105.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V TTL PF03133.15 EGB13151.1 - 7.2e-18 64.7 0.0 2.9e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family EGF_Tenascin PF18720.1 EGB13152.1 - 0.0014 18.6 15.7 0.0014 18.6 15.7 6.8 6 0 0 6 6 6 1 Tenascin EGF domain Trypan_glycop_C PF10659.9 EGB13152.1 - 0.0015 18.8 24.9 0.0015 18.8 24.9 11.5 7 2 4 12 12 12 6 Trypanosome variant surface glycoprotein C-terminal domain Gal-3-0_sulfotr PF06990.11 EGB13153.1 - 2.3e-09 36.7 2.0 4.3e-08 32.4 2.0 2.2 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase UNC-50 PF05216.13 EGB13154.1 - 7.3e-60 202.3 2.8 1e-59 201.8 2.8 1.1 1 0 0 1 1 1 1 UNC-50 family EF-hand_1 PF00036.32 EGB13154.1 - 2.7e-13 48.4 0.2 7.3e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGB13154.1 - 6.3e-12 44.4 0.4 4.2e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGB13154.1 - 1.3e-11 44.8 0.0 2.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB13154.1 - 3.4e-11 42.1 1.0 0.00011 21.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGB13154.1 - 1.5e-07 31.2 0.1 4e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 EGB13154.1 - 0.00039 20.7 0.0 0.00097 19.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EGB13154.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand IQ PF00612.27 EGB13154.1 - 0.75 9.7 13.8 0.36 10.7 0.5 4.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif eIF-5a PF01287.20 EGB13155.1 - 4.3e-25 87.6 0.2 6e-25 87.1 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGB13155.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Radical_SAM PF04055.21 EGB13156.1 - 9.3e-14 52.1 0.0 2e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Mpv17_PMP22 PF04117.12 EGB13157.1 - 4.8e-17 61.9 3.3 4.8e-17 61.9 3.3 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family DUF563 PF04577.14 EGB13158.1 - 6.3e-19 68.9 0.0 1.4e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DNA_methylase PF00145.17 EGB13158.1 - 0.0015 18.0 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase DUF4576 PF15144.6 EGB13158.1 - 0.029 14.3 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) Acid_PPase PF12689.7 EGB13159.1 - 3.2e-37 128.0 0.0 4.4e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase CSD PF00313.22 EGB13159.1 - 1.3e-07 31.4 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Dynein_light PF01221.18 EGB13161.1 - 8.2e-24 83.8 0.0 9.4e-24 83.6 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Abhydrolase_8 PF06259.12 EGB13161.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase TENA_THI-4 PF03070.16 EGB13162.1 - 7.5e-20 71.7 0.0 9.8e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Myosin_head PF00063.21 EGB13163.1 - 2.1e-192 640.9 0.0 2.6e-192 640.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EGB13163.1 - 2e-06 27.6 0.0 5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EGB13163.1 - 3.9e-05 23.9 0.0 0.0058 16.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EGB13163.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 EGB13163.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 EGB13163.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.17 EGB13163.1 - 0.12 12.1 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 EGB13163.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sulfatase PF00884.23 EGB13164.1 - 1.7e-12 47.4 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EGB13164.1 - 0.00038 19.9 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily AlaDh_PNT_N PF05222.15 EGB13165.1 - 4.6e-27 95.0 0.0 8.4e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGB13165.1 - 0.016 14.5 0.0 0.35 10.1 0.0 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Exo_endo_phos PF03372.23 EGB13166.1 - 6.7e-10 38.9 0.7 7.3e-09 35.5 0.3 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PNK3P PF08645.11 EGB13166.1 - 5.2e-05 23.0 0.0 9.6e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase UBA_4 PF14555.6 EGB13166.1 - 0.019 14.8 0.7 0.019 14.8 0.7 1.9 2 0 0 2 2 2 0 UBA-like domain YbaB_DNA_bd PF02575.16 EGB13167.1 - 1.2e-11 44.7 6.6 2.1e-11 43.9 6.6 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Ion_trans_2 PF07885.16 EGB13168.1 - 7.1e-26 90.0 6.2 5.4e-14 51.9 0.6 2.4 2 0 0 2 2 2 2 Ion channel Exostosin PF03016.15 EGB13168.1 - 1.2e-09 37.9 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Ion_trans PF00520.31 EGB13168.1 - 0.0025 17.1 0.1 0.28 10.4 0.0 2.1 2 0 0 2 2 2 2 Ion transport protein Exostosin PF03016.15 EGB13169.1 - 3.3e-10 39.7 0.0 6.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Myosin_head PF00063.21 EGB13170.1 - 2e-183 611.3 0.0 2.5e-183 611.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EGB13170.1 - 0.00094 19.0 0.2 0.0029 17.4 0.1 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EGB13170.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 EGB13171.1 - 3.3e-05 24.7 0.0 6.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1176 PF06674.11 EGB13171.1 - 3.6 6.9 6.0 6.3 6.1 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Ndc1_Nup PF09531.10 EGB13171.1 - 7.6 5.1 6.7 9.9 4.7 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CENP-T_C PF15511.6 EGB13172.1 - 8.2e-09 35.6 0.0 9.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGB13172.1 - 0.00011 22.5 0.1 0.00014 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGB13172.1 - 0.00017 21.7 0.1 0.00021 21.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGB13172.1 - 0.0026 18.0 0.1 0.0034 17.6 0.1 1.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGB13172.1 - 0.0029 18.0 0.0 0.0029 17.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGB13172.1 - 0.014 15.5 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGB13172.1 - 0.03 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TPT PF03151.16 EGB13173.1 - 3.5e-66 223.5 4.9 3.9e-66 223.4 4.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGB13173.1 - 3.3e-10 40.3 18.4 6.8e-07 29.5 4.2 2.4 1 1 2 3 3 3 2 EamA-like transporter family UAA PF08449.11 EGB13173.1 - 0.072 12.3 4.0 0.09 12.0 4.0 1.2 1 0 0 1 1 1 0 UAA transporter family UCR_14kD PF02271.16 EGB13173.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit EF-hand_1 PF00036.32 EGB13174.1 - 3.2e-10 38.8 1.1 0.0005 19.4 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGB13174.1 - 1.1e-09 37.4 0.6 0.0021 17.9 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EGB13174.1 - 5.5e-08 33.2 2.7 3.3e-06 27.4 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 EGB13174.1 - 4.2e-07 29.2 0.3 0.24 11.0 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGB13174.1 - 4.9e-06 26.3 2.0 0.063 13.1 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGB13174.1 - 0.0055 17.0 0.2 2.3 8.5 0.0 2.6 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region CRAL_TRIO PF00650.20 EGB13175.1 - 2.3e-17 63.1 0.0 3.1e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Pkinase PF00069.25 EGB13176.1 - 1.1e-48 165.9 0.0 1.2e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGB13176.1 - 9e-32 110.4 0.0 9.7e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGB13176.1 - 3.4e-06 27.2 0.0 5.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGB13176.1 - 2.1e-05 24.0 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGB13176.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGB13176.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family OMPdecase PF00215.24 EGB13177.1 - 1.1e-29 103.7 0.1 1.2e-29 103.5 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 EGB13178.1 - 4.2e-17 62.1 1.3 6.3e-17 61.5 1.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EGB13178.1 - 0.0017 18.4 0.2 0.0024 17.9 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 EGB13178.1 - 0.066 12.6 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Arm PF00514.23 EGB13179.1 - 2.6e-70 230.5 15.8 2.1e-09 37.1 0.1 10.0 10 0 0 10 10 10 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGB13179.1 - 5.3e-13 49.2 13.8 0.0058 17.0 0.2 5.0 4 1 1 5 5 5 5 HEAT repeats KAP PF05804.12 EGB13179.1 - 1.4e-06 26.8 0.1 0.3 9.2 0.0 3.1 1 1 0 3 3 3 3 Kinesin-associated protein (KAP) Arm_2 PF04826.13 EGB13179.1 - 1.7e-05 24.4 2.8 0.24 10.8 0.0 3.9 1 1 1 3 3 3 2 Armadillo-like HEAT_EZ PF13513.6 EGB13179.1 - 0.00013 22.4 24.3 0.66 10.6 0.4 6.5 5 1 1 6 6 6 4 HEAT-like repeat Atx10homo_assoc PF09759.9 EGB13179.1 - 0.00037 20.5 2.4 0.21 11.7 0.4 4.4 4 1 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DUF5578 PF17741.1 EGB13179.1 - 0.00039 19.9 2.8 4.2 6.7 0.0 4.2 2 1 3 5 5 5 1 Family of unknown function (DUF5578) V-ATPase_H_N PF03224.14 EGB13179.1 - 0.0012 18.2 1.9 0.21 10.8 0.2 2.9 1 1 1 3 3 3 2 V-ATPase subunit H DUF383 PF04063.14 EGB13179.1 - 0.098 12.3 2.8 4.8 6.8 1.3 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF383) HEAT PF02985.22 EGB13179.1 - 0.62 10.5 27.8 6.4 7.3 0.3 8.3 10 0 0 10 10 10 0 HEAT repeat DnaJ_CXXCXGXG PF00684.19 EGB13180.1 - 2.4e-05 24.6 12.7 0.0094 16.3 2.5 2.4 1 1 2 3 3 3 3 DnaJ central domain DUF1356 PF07092.12 EGB13180.1 - 1.2 8.3 4.3 1.7 7.9 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) DUF5351 PF17302.2 EGB13180.1 - 1.5 9.1 19.2 59 4.0 11.9 4.0 2 1 0 2 2 2 0 Family of unknown function (DUF5351) RRM_1 PF00076.22 EGB13181.1 - 3.8e-20 71.5 0.0 4.1e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sel1 PF08238.12 EGB13182.1 - 2.6e-21 75.6 12.9 3.9e-09 36.9 0.2 4.5 4 1 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 EGB13182.1 - 0.00042 20.9 15.8 0.093 13.4 9.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGB13182.1 - 0.22 11.8 12.4 0.13 12.6 4.5 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGB13182.1 - 0.77 9.7 13.1 0.12 12.3 2.3 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Chloroa_b-bind PF00504.21 EGB13183.1 - 2.1e-39 135.6 0.1 2.6e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Nuc_sug_transp PF04142.15 EGB13184.1 - 5.3e-35 121.1 4.6 6.4e-35 120.8 4.6 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGB13184.1 - 2.2e-06 27.9 2.8 2.2e-06 27.9 2.8 3.1 2 1 1 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 EGB13184.1 - 2.3e-05 23.8 1.0 2.8e-05 23.5 0.5 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 EGB13184.1 - 0.0011 18.6 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 Solute carrier family 35 TPT PF03151.16 EGB13184.1 - 0.017 14.5 0.3 0.03 13.7 0.3 1.4 1 0 0 1 1 1 0 Triose-phosphate Transporter family Dus PF01207.17 EGB13185.1 - 7.7e-37 127.0 0.2 9.2e-37 126.8 0.2 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SpoU_methylase PF00588.19 EGB13186.1 - 1.1e-29 103.4 0.0 1.3e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF3458_C PF17432.2 EGB13187.1 - 1.5e-103 346.5 9.3 2.4e-103 345.9 9.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 EGB13187.1 - 2.2e-52 177.8 0.2 4.8e-52 176.7 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M1 domain NAD_binding_1 PF00175.21 EGB13187.1 - 1.4e-23 83.6 0.0 2.5e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3458 PF11940.8 EGB13187.1 - 1.7e-20 73.2 0.0 3.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold FAD_binding_6 PF00970.24 EGB13187.1 - 3.6e-20 72.2 0.0 7.2e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Peptidase_M1_N PF17900.1 EGB13187.1 - 1.1e-13 51.8 0.0 1.8e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain NAD_binding_6 PF08030.12 EGB13187.1 - 0.0012 19.0 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Peptidase_M61 PF05299.12 EGB13187.1 - 0.0082 16.5 0.2 0.023 15.1 0.2 1.8 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Phage_TAC_6 PF09550.10 EGB13187.1 - 0.04 14.4 0.3 0.16 12.4 0.3 2.1 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC EXS PF03124.14 EGB13188.1 - 7.4e-29 101.1 4.0 8.5e-29 100.9 4.0 1.0 1 0 0 1 1 1 1 EXS family Pro_dh PF01619.18 EGB13189.1 - 6.7e-40 137.5 0.0 9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase CS PF04969.16 EGB13190.1 - 2.3e-08 35.0 0.0 3.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 CS domain Pro_isomerase PF00160.21 EGB13191.1 - 9.8e-12 45.4 0.0 1.1e-11 45.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DHC_N2 PF08393.13 EGB13193.1 - 4.2e-20 72.2 0.1 2e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 HSDR_N PF04313.14 EGB13193.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) JmjC PF02373.22 EGB13194.1 - 3.7e-06 27.3 0.2 6.3e-05 23.4 0.2 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGB13194.1 - 7.3e-06 25.9 0.0 2.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain RPN7 PF10602.9 EGB13195.1 - 9.3e-41 139.4 1.4 1.3e-40 138.9 1.4 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGB13195.1 - 3.5e-13 50.0 0.0 9.6e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain IF-2B PF01008.17 EGB13196.1 - 1.6e-54 185.1 0.0 1.9e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 EGB13196.1 - 0.076 13.0 0.1 2.5 8.0 0.0 2.3 2 1 0 2 2 2 0 DeoR C terminal sensor domain V-SNARE_C PF12352.8 EGB13197.1 - 9.3e-10 38.7 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EGB13197.1 - 0.00036 20.8 1.0 0.0016 18.7 0.8 2.2 1 1 1 2 2 2 1 Vesicle transport v-SNARE protein N-terminus SLAIN PF15301.6 EGB13197.1 - 0.012 14.9 0.2 0.012 14.9 0.2 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family OEP PF02321.18 EGB13197.1 - 0.043 13.6 0.8 0.061 13.1 0.0 1.6 2 0 0 2 2 2 0 Outer membrane efflux protein HrpB7 PF09486.10 EGB13197.1 - 0.051 14.0 6.6 0.02 15.3 3.2 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) zf-C3HC4_3 PF13920.6 EGB13198.1 - 3.1e-12 46.2 17.1 4.9e-09 35.9 5.3 9.1 8 2 3 11 11 11 3 Zinc finger, C3HC4 type (RING finger) Lectin_C PF00059.21 EGB13198.1 - 1.1e-11 45.4 1.4 2.4e-11 44.3 1.4 1.5 1 0 0 1 1 1 1 Lectin C-type domain Ephrin_rec_like PF07699.13 EGB13198.1 - 3.7e-06 26.6 12.8 5.8e-06 26.0 3.1 6.5 9 1 1 10 10 10 3 Putative ephrin-receptor like IBR PF01485.21 EGB13198.1 - 5.2e-06 26.6 0.0 5.2e-06 26.6 0.0 8.0 5 4 2 7 7 7 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGB13198.1 - 0.0067 16.7 6.3 0.0067 16.7 6.3 8.5 5 1 2 7 7 7 4 Ring finger domain zf-RING_UBOX PF13445.6 EGB13198.1 - 0.013 15.5 2.4 0.013 15.5 2.4 6.6 6 0 0 6 6 6 0 RING-type zinc-finger Aminotran_5 PF00266.19 EGB13199.1 - 4.2e-87 292.5 0.0 5.2e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGB13199.1 - 1.4e-06 27.8 0.1 1.9e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGB13199.1 - 0.0012 18.2 0.3 0.0019 17.6 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family STAG PF08514.11 EGB13200.1 - 0.0035 17.2 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 STAG domain Ins145_P3_rec PF08709.11 EGB13201.1 - 1.1e-08 34.5 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 EGB13201.1 - 4.2e-05 23.0 0.1 0.33 10.3 0.0 3.4 4 0 0 4 4 4 2 RIH domain MIR PF02815.19 EGB13201.1 - 0.0037 17.2 0.2 0.1 12.5 0.1 2.4 2 0 0 2 2 2 1 MIR domain Sulfotransfer_2 PF03567.14 EGB13202.1 - 0.0014 18.6 0.0 0.0027 17.6 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase family Isochorismatase PF00857.20 EGB13203.1 - 3.3e-36 125.1 0.1 3.7e-36 124.9 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF711 PF05167.12 EGB13204.1 - 7e-93 311.7 0.0 1.2e-92 311.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) Glyco_transf_41 PF13844.6 EGB13204.1 - 4.8e-22 78.0 0.0 1.6e-16 59.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 41 LtrA PF06772.11 EGB13204.1 - 9.7e-20 71.1 15.0 2.6e-19 69.7 13.5 2.3 2 1 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DSPc PF00782.20 EGB13204.1 - 3.2e-12 46.4 0.0 6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Glyco_transf_25 PF01755.17 EGB13204.1 - 3.2e-06 27.2 0.0 2.6e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NADH_Oxid_Nqo15 PF11497.8 EGB13204.1 - 0.028 14.4 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 SelR PF01641.18 EGB13205.1 - 9.6e-40 135.4 0.0 1.3e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EGB13205.1 - 0.026 14.2 0.1 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein VCBS PF13517.6 EGB13206.1 - 1.7e-23 82.9 53.8 4.4e-07 30.4 10.3 6.3 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Laminin_G_3 PF13385.6 EGB13206.1 - 8.7e-17 61.7 0.2 8.7e-17 61.7 0.2 2.5 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.21 EGB13206.1 - 3.4e-06 27.5 0.6 9.1e-06 26.1 0.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif FG-GAP PF01839.23 EGB13206.1 - 0.00052 20.1 0.8 0.00052 20.1 0.8 8.1 8 0 0 8 8 8 4 FG-GAP repeat Tetraspanin PF00335.20 EGB13206.1 - 0.012 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family Pentaxin PF00354.17 EGB13206.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Pentaxin family Laminin_G_2 PF02210.24 EGB13206.1 - 0.12 13.0 0.0 0.47 11.0 0.0 2.0 1 0 0 1 1 1 0 Laminin G domain PH PF00169.29 EGB13207.1 - 4.7e-06 27.1 0.0 6.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGB13207.1 - 0.037 14.5 0.4 0.86 10.1 0.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Pex19 PF04614.12 EGB13208.1 - 5.1e-29 101.8 3.9 5.9e-29 101.6 3.9 1.0 1 0 0 1 1 1 1 Pex19 protein family BACK PF07707.15 EGB13208.1 - 0.037 14.1 0.2 0.062 13.4 0.2 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch 2OG-FeII_Oxy_3 PF13640.6 EGB13209.1 - 7.4e-14 52.4 0.0 1.5e-13 51.4 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGB13209.1 - 1.3e-06 29.0 0.0 2.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GDYXXLXY PF14345.6 EGB13209.1 - 0.14 12.0 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 GDYXXLXY protein CAP_N PF01213.19 EGB13209.1 - 0.29 10.6 3.0 0.39 10.1 3.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal OAD_gamma PF04277.13 EGB13209.1 - 0.64 10.6 2.1 1.3 9.7 2.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_C1 PF00112.23 EGB13210.1 - 3e-55 187.7 14.3 3.9e-55 187.3 14.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGB13210.1 - 1.5e-10 41.4 1.0 2.2e-10 40.8 1.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGB13210.1 - 0.12 11.1 6.1 2.5 6.8 0.2 2.5 2 1 0 2 2 2 0 Peptidase C1-like family Anoctamin PF04547.12 EGB13211.1 - 1.3e-84 284.7 0.0 1.5e-84 284.5 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel EXS PF03124.14 EGB13212.1 - 2.9e-60 204.3 0.5 4e-60 203.9 0.5 1.2 1 0 0 1 1 1 1 EXS family TPALS PF18178.1 EGB13212.1 - 0.1 12.0 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Sulfotransfer_2 PF03567.14 EGB13212.1 - 0.17 11.8 0.0 4.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase family CRAL_TRIO PF00650.20 EGB13213.1 - 5.9e-08 32.6 0.0 8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Metallophos PF00149.28 EGB13214.1 - 1.3e-39 136.8 0.1 1.7e-39 136.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGB13214.1 - 6.4e-19 68.1 0.2 1.1e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Sulfotransfer_3 PF13469.6 EGB13215.1 - 6.3e-09 36.5 0.0 1.8e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EGB13215.1 - 1.1e-08 34.9 0.0 4.4e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_tranf_2_4 PF13704.6 EGB13216.1 - 2.2e-11 44.1 0.0 6.5e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EGB13216.1 - 3.7e-05 23.5 0.0 0.00018 21.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 92 TPR_2 PF07719.17 EGB13217.1 - 7.9e-13 47.5 0.1 2.1e-07 30.5 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGB13217.1 - 1.1e-11 44.1 0.8 4.7e-06 26.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGB13217.1 - 8.6e-07 28.9 0.2 0.0056 17.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGB13217.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGB13217.1 - 0.00018 21.7 0.0 0.11 12.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGB13217.1 - 0.0012 18.9 0.0 0.0083 16.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGB13217.1 - 0.0033 18.0 0.1 0.06 14.0 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGB13217.1 - 0.004 17.8 1.6 0.3 12.0 0.0 4.0 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGB13217.1 - 0.009 16.5 0.0 0.16 12.5 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGB13217.1 - 0.015 15.5 0.1 0.032 14.4 0.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EGB13217.1 - 0.061 13.4 0.0 1.1 9.3 0.0 2.4 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Pelagophyta/Aureococcus_anophagefferens-v1.0/GCA_000186865.1_v_1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Pelagophyta/Aureococcus_anophagefferens-v1.0/GCA_000186865.1_v_1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Pelagophyta/Aureococcus_anophagefferens-v1.0/GCA_000186865.1_v_1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Pelagophyta/Aureococcus_anophagefferens-v1.0/GCA_000186865.1_v_1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 10:57:43 2019 # [ok]